How many of your PhD students, so the day of your calls is the day you are the smartest you will ever be in the history of your life. And I would also argue that after this week, you might be the smartest that you'll ever be in terms of like breadth of energy in your whole life. And actually, you guys, you know, Arpita and the team putting this together is phenomenal. I know it's a lot of work. I was a PhD student in MIT a decade ago, and we didn't have anything like this. And so when you're trying to find people to go change the world with an energy and climate was really hard to find them. So I think you're in a really great situation. So how many of you are interested in creating a startup in energy or climate out of your Stanford experience? How many of yours didn't join a startup potentially? And how many of you want to be professors? All right, so I think all of you would benefit from taking our course, the energy transformation collaborative. I think there aren't MBA students here, right? So the MBA students, when they see the name energy transformation collaborative, they think that we're doing like drum circles and stuff like that. But I want to be clear to you, this is a hardcore energy ventures class. Or you're going to learn a lot of major skills. You're going to really build a tool set. You're going to learn how to launch new ventures. And if our track record holds true this year, 40% of the teams are going to launch new companies. And so I want to start by introducing our team, our team of instructors. We have a dream team here, starting with Joel Moxley, who's over here if you can raise your hand. Joel and I were contemporaries at MIT. We got our PhDs at the same time, kind of when MIT went through a big focus on energy. And we've had our careers and energy ever since. And Joel's story to me kind of started, he's a consummate entrepreneur. He kind of eats and breathes entrepreneurship every moment of every day. And the kind of the epitome of his story is that when he was a PhD student, this was the early days of data analytics and before Moneyball, he took $300 and turned it into $3,000 and turned it into $300,000 using data analytics to put that on baseball when it was legal, when it was legal. Since then, Joel has been a founder of multiple energy companies and other companies that he's sold and is now also an investor in a number of companies across the spectrum of energy in other areas, including an early investor in a company called Rubicon Global, which is a unicorn that essentially is a multi, a more than billion dollar value company that is kind of like the Uber or Trash collection. And Joel and I are actually work together at Breakthrough Energy Ventures, which I'll say a word about in a second. And then Stuart, we like to call it the silent or quiet assassin. He actually brings a wealth of experience from all the way back like Sun Microsystem. So he's been in Silicon Valley through, I'd say, the multiple generations of advanced technology. So I think he brings a ton of expertise in startups and especially around, I'd say, exponential technology driven startups, like especially around machine learning, AI, data analytics, these kind of areas. And he speaks about 10% of the time and delivers 80% of the value in the course. And then myself, Dave Danielson, I am a managing director of Breakthrough Energy Ventures now, which is a $1.3 billion new investment fund that Bill Gates and Jeff Bezos and 20 other people who add up to about half a trillion dollars of net worth have created to invest in the climate tech game-changing companies of the future. And for that, I was the assistant secretary of energy efficiency and renewable energy at DOE, where I oversaw the nation's clean energy research and development programs and was also a founder of ARPA-E, which is kind of like a high risk, high reward part of DOE that really kind of backs game changer technologies and did my PhD in material science for that. And so, just to tee this up, I think you've probably heard a lot about the problem, but I'll just provide the context once again, is that in my mind, clean energy and climate is the defining challenge and the defining opportunity of our time. If you look at where we are today, energy usage is correlated with human development. And a large part of the world, I say, five or six billion people don't have access to the amount of energy that they need to reach a level of human development that we have in North America, Europe, and other kind of more developed nations. And so, as we go from now to the, let's say the mid-century 2050, it's going to be a great thing for those people to get access to more and more cheap energy so that they can raise their human development index and their well-being. So there are people all over the world who are going to be driving at least a doubling of energy usage out to 2050. At the same time, as I'm sure you've heard a lot about, our scientists are now clear that if we don't reduce our greenhouse gas emissions by 80% or more by the middle of the century, then we're toast. So we've got to double the amount of energy at least over the next 30 years or so, and we've got to reduce the footprint by a factor of five. So it's a 10x kind of problem. This is a huge problem, and it's going to require a lot of work. And so what I also want to give you a little bit of context in is that 2050 can feel far away. Once you have a kid, it doesn't feel far away, but it can feel pretty far away. 2050, so let's say we've got about 30 years, we can kick back a little bit, right? 80% greenhouse gas production by 2050. If you create a disruptive new technology and it's in the market and it's working, it's going to take you, I'd say, aggressively 20 years to get to a meaningful scale, a scale that would make a dent in this problem. And then if you kind of work backward, so that means you've got to get any new product, if you're going to disrupt, if you're going to really solve this problem, you've got to get a new game-changing product into the market by 2030 commercially. And any real hard tech, especially major new technologies, is going to take you 10 years from idea to commercialization. And so if you really think about this and you work backwards, it's really like now and over the next two, three, four, maybe five years that the 2050 impact startups need to be created. And so my view is that you're in a really unique time and unique place where you're in the hub of global entrepreneurship. Also, I'd say one of the leading hubs of energy thought leadership and innovation. And you're also just happening to be here at the time that's essentially the last five years where building a startup is going to affect 2050. So you're at a really important time and place. And that's what this class is all about. We're really at the intersection of energy and climate and the kind of unique entrepreneurial spirit that is really embodied in the Stanford community. And so what we're really all about here is what's interesting is many of you probably tracked there's this clean tech boom bust in the kind of early 2000s, late 2000s, where a whole bunch of money went into these clean energy ventures and there were a massive number of failures. And so what we saw was this big, big boom and then a bust and now we're coming out and funding is coming back and entrepreneurship is coming back. And one thing that we need to be doing and we're doing a breakthrough and that we're doing in this class is we need to together develop a new playbook for how to build these major impact climate tech companies. And so part of what we're doing in this class is we have playbooks of the right way to build these companies and we're continuing through our experience of breakthrough energy ventures and elsewhere to continue to build out what are the playbooks it's going to take and I think working with you in this class we're going to continue to write chapters of the playbook required to build successful clean tech and climate tech startups. The other thing we want to do is put in your hands tools that you can put in your tool belt for the rest of your career that will allow you, I'd say not only to launch new ventures and be successful in startups but also in some sense what I found is non MBAs are kind of getting like a 10 week accelerated MBA in this class and we kind of teach both at a level where if you don't know anything about business you're going to learn a lot and if you're an MBA who's pretty far up the curve you're going to learn a lot as well. And then finally like I said about 40 we have about 40% of our teams over the last two years have resulted in the launch of a transformative new venture and so I think not only are you going to get the tools in the tool belt but there's a reasonable shot that if you join one of these teams a company is going to come out of it. And so just some of the basics we really are focusing on giving you this replicable tool set that allows you to identify interesting opportunity areas to assess to analyze and assess whether those areas are right for a new venture and then to really design and develop a game plan for launching a new venture. And that's a replicable skill set you can apply to any problem over the rest of your career. Every quarter we have about four or five project teams that are on the order of four or five, six people so it's about 20 to 30 students each quarter we run this every quarter. This is project-based so what we do is we recruit embryonic new venture concepts and usually people who have those either it could be someone looking at an intersectional opportunity of two megatrends that haven't been solved. For example, we're running out of cobalt for electric vehicles we want to go look at that and find a venture opportunity or it could be someone coming in I got a technology out of Stanford lab and I want to go create a startup. And so there's a lot of flexibility but we really build around we have four or five embryonic new venture concepts that then we build teams around. And so you can have an idea and lead a team or you can just come in and say hey I want to be involved I want to join one of these teams. And my mainly graduate students and just a few undergrads have been involved I think one thing that's really valuable about the course is it's very multidisciplinary so it's about half MBA students and half non MBA so more technology engineering students and I think you find that you're able to learn a lot from each other and actually do things that you never could have done without each other which I think is exciting. And we're also going to expose you to some of the leaders in the clean energy and climate field. So we've had leaders like Vinod Posla one of the most important venture capitalists in Silicon Valley and in energy. Jagdeep Singh who is a Stanford alum who's created multiple billion dollar companies and is now leading a billion a more than billion dollar valued company developing a next gen solid state battery. And a whole bunch of other interesting people that you're going to get to hear from and get really kind of candid perspectives kind of behind closed doors candid perspectives and kind of hear about their journey their insights and ideas that they have for areas that if they were starting over again they would look to launch new ventures in. And so in terms of just the results that we've seen over the last couple of years is 120 students getting a really exciting new set of tools a new skill set that they are able to apply to other parts of their life and career. You know like I said if you're a professor you may spin out a company or you may have someone spin out a company from your lab. I think you're going to want to understand understand even if you're not going to go leave with the venture if you're going to be involved in it I think you want to understand how that works.  So we've got 25 project teams over the last three years and 10 new companies have launched from those teams. And four of those have already gotten private investment I think it's probably above three million now of private you know venture investment in addition to probably twice that amount of government funding and grants. And two of these companies already have revenue you know in a very short period of time. And so we've got AI Onyx actually so our our TA is going to be Austin Sendek who's defending his PhD thesis in in two weeks so he's probably not listening to anything that I'm saying. But he's going to be our TA he took the course and out of the he looked at the intersect he was doing research on machine learning applied to battery innovation and ended up doing a lot of exploration and turning over a lot of rocks and ultimately finding a really great business model for starting a new company in this area and has now launched the company and actually has revenue with major parties on the outside. Climate AI is a company that was taking kind of advanced modeling simulation of climate and climate impacts to provide risk mitigation services to the industry and insurance insurance industry and others. Moraine is looking at optimization of charging of autonomous electric vehicles fleets in the future. Safi Analytics is looking at they've actually now launched their company in Kenya and is building a company to do kind of advanced meter and data analytics driven industrial energy management for industrial companies in Africa. And Ferbo I think you may have heard from Tim already on but I wanted to use Ferbo as a really interesting I think case study of what it's like to do a project here. So Tim had come from the auto industry and then was in the shale patch in Texas where he learned a ton about the emerging technology of horizontal drilling and multisonal stimulation and they came to Stanford and was really interested in applying that to geothermal. And so he took our class one quarter and worked on a different project than the second quarter. He launched into a very aggressive effort to explore this intersectional opportunity and was able to recruit a really amazing team of people from you know things that are half MBA half PhD postdocs on this team and it ended up resulting in a couple of these folks going and launching the company but I think everyone else gained an amazing new skill set that now they're applying to other things that they're doing out in the world today. And I think you already heard about this but you know I think this is an example I think of like a potentially game-changing venture and I just saw today that the United States just surpassed oil production of Saudi Arabia for the first time and anyone can remember just in the last month or so and that was because of the shale revolution. Imagine a world where you know when you look at the 2050 everyone thinks there's like zero geothermal but if Tim and his team are successful then we may be looking back and saying holy crap I can't believe that we we didn't realize that geothermal was going to be the next shale boom. So if you're interested please get in touch with us send us a note follow up with us after outside the way we do this is we accept a lot of people's ideas for project concepts that they want to lead and then we select four or five of those project concepts that we think have the most promise to be good projects in our class and then individuals who just want to get involved we invite you to sign up for the class reach out to us and we'll get you connected to the people who are rallying these projects so that you can try to find good fits and join teams that will be a good experience for you and so we'll work hard to get you connected to the right kind of team. If you don't take it this quarter you can take it the next quarter or the quarter after and so thank you for your time you know we we get really excited about investing a substantial amount of our time here because we know how unique students are here and how entrepreneurial they are and so you know we're excited about putting time into you because we really believe that you know if you really invest in yourself and think big here that you can be the people that are actually creating these these companies they're going to solve the 2050 climate crisis so thank you very much looking forward to working with you guys


This video contains a proof of the factorial formula, which says that n choose x is equal to n factorial divided by x factorial times n minus x factorial. I'm going to do this by explaining why ten choose three is equal to ten factorial divided by three factorial times seven factorial. Okay, so suppose that we've got ten Scrabble tiles, three of which are marked with an s, and seven of which are marked with an f. Ten choose three is the number of different words that can be made with three s's and seven f's. So the question we need to answer is how many words can be made with these Scrabble tiles. Now there's an important subtlety that you need to understand from the very beginning. You can rearrange the tiles to make a new word, but not every rearrangement of the tiles produces a different word. For example, in this word here, I can take out the s's and put them back again in a different order. So this is a different rearrangement of the tiles, but it's not a new word. And of course I can also take out the f's and rearrange them. And I can produce another arrangement of the tiles which spells the same word. So when we're asking how many words can be made, we need to understand that the number of arrangements of the tiles is much greater than the number of words. In fact, the total number of arrangements of the tiles is the number of words times the number of arrangements per word. Or, put a different way, the number of words is equal to the total number of arrangements of the tiles divided by the number of arrangements per word. So in order to answer the question how many words can be made, we need to ask two questions. How many arrangements of the tiles are there? And secondly, how many arrangements are there per word? Let's deal with the first question first. How many arrangements of the tiles are there? So let's suppose that we're going to put the ten tiles down one at a time, going from left to right. For the first tile, there are ten options because you've got ten tiles to choose from. We can pick any of these tiles, but just for the sake of illustration, suppose that we pick f3. Next we've got to pick a second tile, but at this stage things are different because there are only nine tiles left. So there are only nine possibilities for the second tile. And this means that overall there are ten times nine possibilities for the first two tiles. Now there are only eight tiles left and only eight possibilities for the third tile. So for the first three tiles, the number of possibilities is ten times nine times eight. You can see that if we carry on in this way, there are seven possibilities for the fourth tile, six possibilities for the fifth tile, five possibilities for the sixth tile, four possibilities for the seventh tile, three possibilities for the eighth tile, two possibilities for the penultimate tile, and only one possibility for the last tile. So in total for all ten tiles, the number of possible ways of putting them down is ten times nine times eight times seven times six times five times four times three times two times one, which is ten factorial. The second question that we need to ask is how many arrangements of the tiles are there per word? So let's look at a word, this is the one that we constructed a moment ago, and see how many ways there are of rearranging the tiles to get the same word. Well what we can do is to take out the S's and put them back in again, seeing how many ways there are of doing this. Well, there are three tiles, so for the first tile that we put back in, there are three possibilities. For the next tile, there are only two possibilities, which gives us a total of three times two possibilities so far. There's obviously only one possibility for the last tile, so the total number of possibilities for taking out the S's and rearranging them is three times two times one. Next we need to take out the F's and see how many ways there are of putting those back into the word. To begin with we have seven F's, so there are seven possibilities for the first replacement. Now though there are only six F's left, so there are six possibilities for the second letter. Now there are five, so there are five possibilities for the third letter, and so on as before. You can see that the total number of ways of rearranging the letters to spell the same word is three times two times one times seven times six times five times four times three times two times one, which is three factorial times seven factorial. We've now shown that the total number of ways of arranging the tiles is ten factorial, and the number of rearrangements for each word is three factorial times seven factorial. This means that the total number of words is ten factorial over three factorial times seven factorial. But remember that the number of words we can make is ten choose three. So we've shown that ten choose three is equal to ten factorial divided by three factorial times seven factorial. Now it's clear that I could go through this explanation using the letters N and X in place of ten and three. And so this proves that N choose X is equal to N factorial divided by X factorial times N minus X factorial. Thank you for watching this video.


Good afternoon, everyone. Thank you for joining me. I'm Kathleen Bergman, Director of Career Leadership and Professional Development as part of the Academic and Career Development Center here at Fairfield University. Today's session is going to explore the realities of internships and what you can do to encourage your student through the process. So you might ask yourself, are internships important? Yes, they are very important. However, keep in mind that it is challenging for younger students to always get the best internships because they're competing against a lot of older students as well. The point is they really need to be at least trying or in the game. Students need at least one or several relevant experiences before graduating from Fairfield. Even if an experience is not a true internship or related to career goals, it says a lot when the resume shows someone has been industrious throughout their time in college. More and more organizations and grad programs have the expectation that students are out doing things within the workforce. This tells an employer that they have been in professional settings, have gained experiences outside of the classroom, and their minds are really in the game. They want to learn. They want to be doing things. It shows that they've been proactive. Unfortunately, gone are the days when a student could just be a lifeguard the whole four years they're in college. That's my memory of college, but it doesn't work anymore. The good news is 75% of interns receive a full-time offer after interning. The actual conversion rate to full-time is closer to around 50%. Oftentimes, students will be in positions that are great positions, but they realize they don't want to work for that organization. They change their mind, decide they don't want to go into that profession. That's why it's so important to take an internship. This is like an extended interview for the companies, and that's why they oftentimes will make offers to students during the summer. You might ask yourself, where are the jobs and the internships? The reality is the advertised positions only take about 20% of what's out there. There's an actual hidden job market, and that consists of 80% of the opportunities. That's why it's very important for people to network and use the internet and search. The networking is key because that's actually where that hidden job market is located. What should your students be doing? They should be doing all of this. They should be working on the internet, actually taking it on as a job, maybe an extra class, consider it an extra class, and every day spend 45 minutes looking and trying to meet as many people as possible. Networking is a step closer to that hidden job market. It's all about relationship building, collecting information about different careers, about people. It's about developing contacts and access to those people, maybe not right now, but down the road when maybe the time is for a full-time position. Networking is not asking contacts if they have a job or an internship for your child. It's absolutely not easy. It takes time. You need to really build relationships and maintain them, and it's something that's not going to happen overnight. Students really need to understand this. Actually understand all three points because in an age when everyone is looking for immediate results, this isn't going to happen with networking. Slow and steady does win the race. So, why network? Well, the reality is here employers typically hire through referrals. So that's why it's important if you want to get into that hidden job market. The positions never really make it out into the public sector. Think about it, they're hit with thousands and thousands of applications, and if they hear from someone that an individual is a good worker, smart, really in the game, that might help them weed out some of those applications. Of course, they have to do a good job in the interview, but at least you get noticed. Overall, the most influential attributes for internship positions are a student's major, leadership experiences, and the grade point average. It all is factored in. If your child is having a great time at Fairfield, but not really focusing on classes, getting involved, or figuring out what they ultimately might want to do post-grad, they're definitely going to have a more difficult time down the road trying to secure opportunities. It's possible. It's just a little bit more difficult. This is another way things have changed over the years. No longer can someone just hand a slip and say, you go call Mr. Smith, he has an opportunity for you. You really have got to do everything by the book. So where should your child start? Speaking with family members, friends, friends, parents, professors, former school teachers, neighbors, coaches, coworkers, alumni, career services, and LinkedIn. All of these areas should be explored. As I said, times really have changed. If you remember using the want ads in the paper or looking at signs in a window during the summer, you probably looked through binders in your career center to find an internship or a job. Well, those binders are now online and everyone is using some sort of digital device. Finding opportunities really has changed over the years, especially with the technology that's currently in place. And as I said, recruiters get hundreds and hundreds of applications. So it is way more competitive. Our online jobs database where employers who want to hire Fairfield students is stags for hire. It's the first stop for online internship and job posting here at Fairfield. Last year, 2,200 jobs were posted and over 1,700 internships. So there are a significant number of opportunities right there for the taking. Here are some of the general databases that students should look at. They also have a significant number of opportunities. Remember, no one should rely on one job search database. The more you're looking at, the better off you'll be. Because of the technology behind them, it's even more critical to have resumes written for the position your student is going after. Many of these organizations and company sites as well use software that coals out key words so that those resumes that have those words get pushed up to the top. That only increases the importance of working closely with a career counselor. Here are some industry specific databases that they also might want to explore. Students should also look at individual companies. Notice I said companies, multiple companies. They should go to their career or jobs pages regularly because they too post. They should follow companies on LinkedIn. Look at the career site on LinkedIn. Follow companies on Twitter. They need to do all these things. Yes, it's gotten a lot more complicated. So applications submitted at the company websites are actually have a bit of a better odd being seen, but they should be looking at all and applying to all. Other strategies that students can take would be to attend the career fair, which actually occurred here in February, but there are local fairs within their towns and areas. We also have reciprocity with other Jesuit schools. They can get that reciprocity by coming to their career counselor and asking for it. They should follow us at Fairfield AC DC. They should pay attention to notices for career related events, such as alumni panels, industry speakers, company visits. They should be doing all of these different things. Maybe they can't leverage those contacts right away, but if they make those contacts now, remember, networking. Maintain the relationships. Continue the conversation. They actually need to engage in live conversations. That's important. Now, the topic of internships for credit. Why should you consider it? Some companies actually require that students get credit if they are not being paid. This is for legal reasons. So students should actually go and speak with their internship advisor to get this accomplished. They're also important because they can replace traditional elective classes so that students can get credit while they're actually in the job and doing what they think they want to do for a career. Get credit for it. Find out if that's really what they love. And it allows for a little bit more flexibility. Students who do this will get faculty guidance. They will have onsite mentors. And they will be preparing papers. So they really have to think through what they've been doing and be thoughtful about the process. As I said, they should meet with their director of internships or internship coordinator in order to figure out what will best work for them. It's important that they do this before starting an internship in order to get credit. And as you can see, there are specific hour requirements that must be completed and some actual paperwork as well. Students can also do internships for credit. Keep in mind that if your child does this, they will have to pay for the credits. Again, this is something to be discussed with the internship coordinator for their major or their school. It is not included in the academic year tuition. Now, your student has gotten the call. Everyone's excited. You're doing the happy dance. Now what? You want to encourage your child to prepare for the interview. Have them research the company and the position. Make sure they go through some of the most common questions asked in an interview. All of those are located on the academic and career development website. They can meet with a counselor. A counselor can do a mock interview with them. They can use interview stream 24-7 so they can practice online and see what they actually look like in an interview. That too is located on the website free of charge. You want to tell your student and remind them that they need to come up with questions as well. Questions that can't be answered just by looking at the website. Have them print several copies of the resume on actual resume paper so that if in fact people who are interviewing them love them so much, they move them to other people to meet, you want to be able to extend the offer of a fresh copy of the resume. How should students dress? Yes, your student does need a suit. There are industries where people don't wear suits on a daily basis. However, for that initial interview, most of the time they will be required to have one. This even holds true for nursing majors. Occasionally in some of the funkier organizations, maybe a very edgy marketing firm, they won't necessarily need to have a suit, the traditional matching outfit, but they want to have something that is very professional and perhaps somewhat trendy. It amazes me how many students are shocked when I tell them they need to get a suit. They don't need a Brooks Brothers suit to play the part. Nothing's wrong with going to Marshall's or even Goodwill. Goodwill has lots of suits and outfits with the price tags from Nordstrom still on them. Our office actually has started a career closet. So if you find that your child doesn't have a suit or is in a pinch, let the career counselor know. Have them come to our offices and perhaps we have something that might save the day. So your child goes to the interview, they get the position, remind them that when they go to work, they need to dress appropriately at all times. You can look around and see how other people are dressed, but you want to make sure that they're somewhat snappy and remind them of that because they're actually setting a brand. They are establishing a relationship with people and they want everyone to see that they really are top notch. They're there to work and they're taking things seriously. They should pay attention at all times to what they're doing. This is not the time to be on the cell phone, check for texts, listen to headphones, be on Facebook, using Instagram or whatnot. People pay attention to how often students are looking at these things and it's best just to stay focused on the work at hand. If someone provides your student with feedback, be it positive or perhaps negative, they should realize that this is a gift. This is an opportunity for them to correct behavior and actually strengthen their skills. It's not something to really get upset about, they should be thankful. They should always meet deadlines and continuously update their resume at all times. They need to be contributing. Students should be contributing because those that do are actually the ones that are seen as being a great asset. These are the qualities that will turn a summer internship into a full-time hire. Tell them they need to be out there meeting with people, making a name for themselves, not in a bad way, but very quietly go out, introduce yourself, meet people, find out what they do, how they got the positions. They want to establish themselves as being a professional. Remind your child after the internship is over to send a thank you note to the supervisors and anyone else that helped them along the way. Encourage them periodically during the school year to drop them a note, maybe send an email, stop by when they're home for breaks to continue that relationship. Remember, networking, it's critical. Now, we all want to do it. We all have advice. So let me give you a little advice on parental dos and don'ts. Remind your child once again to thank the supervisor at the end of the internship. Encourage them to periodically keep in touch. Advise them to visit the career counselors to update their resumes and any cover letters that they might be doing after the internship. Share information about internship leads that you might have for your student or maybe their friends. Talk to your student about professionalism and how to conduct themselves, workplace, just even the way, you know, gossip's not a positive thing. Things you shouldn't do. Practice asking interview questions with your child. The more they practice, the easier it is. Practice having small talk. It's amazing how many people can go through a meal with their families and not really engage in conversation. This is a perfect way to get used to just having conversations. Offer support during what is a very frustrating time. People get very nervous. They're stressed out. Support knowing somebody's there that has their back. That is significant. Parent don'ts. Do not write your resume or cover letter for your child. Don't make calls on their behalf. Give them the information and let them make the connection. This shows a sign of maturity and somewhat respect on the other end when people hear from them. Do not apply to internships or jobs. In other words, don't go on stags for hire for them.  That is one way to get them branded for sure. Don't go on interviews with your student and don't think that Fairfield is going to find these opportunities. We provide the resources. We provide connections, but it is up to your children to actually make things happen. Most of all, don't forget that this is a learning process which will help teach your child down the road. It's something we all went through as painful as it was and we all need to support our children as they learn how to do this as well. Now, this is kind of a crash course on internships and the do's and the don'ts, but if you have any questions, I'd be happy to answer them at this point. We do have some questions. Our first question is, can a first-year student get an internship opportunity? Absolutely. First-year students can get on to stacks for hire from the day that they step foot in September on campus. Many times, however, companies are looking for students who've had a little bit more education, but there are companies that are more than willing to entertain first-year students and they need to get out there. Every year, I'm surprised at the types of opportunities that first-year students have secured. Keep in mind from one of my previous slides that they're also competing against upperclassmen, but that doesn't mean that they can't do it, so you've got to be in it to win it. Our next question is, if my student does not have a hire than a 3.0 GPA, should they still put their GPA on their resume? Good question. We advise students not to put their GPAs on if it's below a 3.0, but that doesn't mean that they cannot apply for jobs, and we can work with them to make sure that all of their bullet points are robust and showing the skills that they have. We can also work with them on their elevator pitch and also their responses so that if someone were to question their GPA, they can respond in a very upbeat, positive way that shows that maybe I did have a few hurdles, but I'm extremely capable and interested in the position, so don't let that stop anyone. When should my child start going to the career fair? We encourage students to start going to the career fair as early as possible. It might be in the first year where they're just walking around and getting a feel for things, but this is a very intimidating situation where you may have 100 companies in one room all very eager to speak with everyone, and when students walk through the door the first time, they're sort of taken aback because even though they've heard that they were all going to be there, they really are not necessarily prepared. So this gives them an opportunity to see the lay of the land, but it also gives them a chance to start to network. There's that word again. With organizations, practice their elevator pitch, learn what they should be saying, get a better understanding of what companies are looking for. So I say the earlier, the better. And our last question is, when should my child have their high school involvements removed from their resumes? We suggest that all high school involvements should be removed by the end of sophomore year. All of those things help to get them into Fairfield. Now it's important for them to really be as involved as possible, to show what they've done during the four years that they're in college. We also tell students right from day one with their resumes that under the education section, you really have to remove all of your high school information.  If it's a school that you have a lot of alums and you know that you're going to be circulating that resume to some of them and you want that on, put that down at the additional information portion of the resume. So that sums it up, I guess. We've completed all of our questions and I hope this helped to answer some of what you've been wondering about for a while. If you do have any further questions, please feel free to email us at acdcatfairfield.edu and I'd be happy to respond. Have a great day.


So one of the things that I can do now that I'm working with a little bit of a spreadsheet I've already built for us is the fact that You notice these titles are starting to go a little further than I really want them to What I can do is say for example, I know why the cage bird sings by Maya Angelou I can double-click on this cell And you're gonna notice that I actually have my cursor now inside of it One of the things I can do while I'm in here is I can say Hold down the alt key and if I press enter Notice what happens it didn't immediately jump to If I just hit enter by itself, it's just gonna immediately jump to the next cell but Holding alt in pressing enter. You notice how it jumps it down now if I hit enter You'll see that the entire row actually gets resized then I'm gonna do this again for reposition yourself reflections Holding alt enter Enter and then once again for interpretation of dreams by Sigmund Freud Now why would I want to do this? Well that allows me to shrink this down a little bit So one of the other things that we can do is let's say for example Let's cut off psychoanalysis if I click on psychoanalysis and I select word wrap up here Notice that'll actually also do it as well. That's pretty nice So one of the things I can do while I'm messing around inside of Microsoft Excel is you can notice I have a price and a quantity for each one of these books Now we started using the idea of cell referencing just a little bit ago so what I can do is I can actually find that sort of a Subtotal if you will and by utilizing cell referencing I start with the equal sign. I can select my G13 times my f13 Even though there's a dollar sign Excel understands that I'm dealing with currency and if I hit enter You see I get the calculated total now as you can guess I probably want to do this for Every one of these I want to do it for the 99 cent thing for the 150 or hundred ten dollar one one of the ways I can do this I can actually click on Sort of my 3990 notice what happens I have a border around my active cell and at the very bottom there I've got this tiny tiny little square right there notice what happened when I moused over it my mouse Changed to this little crosshair effect This is a plus sign. This is a crosshair notice the difference if I click hold and drag downward notice What's happening to my box? It's actually following me and now what will happen as soon as I let go is It's gonna actually take That same math equation notice up here in my address bar my formula bar That's what we typed in g13 times f13 down here g14 f14 Notice what's happening? It automatically was applying sort of the change that we did with it So as I went down it went down pretty nice Now one of the things I can do with this is that obviously I need to make a total and I'll go ahead and add these things together and I will do it the old timey way first equals one Plus two plus three plus four plus five when I hit enter I get Just under the three hundred dollars So one of the things that we're gonna have to factor in is the fact that okay. Well We're in North Carolina. Mr. Fuke is in California, so I'm gonna probably need to do some shipping, you know, so I see that we've got only we've got two digital but we also have Three actual physical copies, so I need to add in a new row One of the things I can do is if I click on row 18, I Can actually come up here to my insert tab. I actually don't even need to it's right there There's the insert tab and if I click on that drop-down menu. You see that I have insert sheet rows And that's actually gonna do exactly that notice what happened. I now have a new row. I can add in Shipping and before I even add in shipping notice my number didn't change this still stayed the same as well It understood that that's pretty nice I type shipping Well, go ahead and add in say maybe I don't know Ten dollars. I know that's a lot now. I do need to effectively add that in so plus H 18 and so now Notice what we've done. We've added in some new little effects


Hello everyone we're live and it's so awesome of you to join me. I know I did advertise this with my practitioner newsletter which is a pretty large group of people so you might be joining me from all over. If you're a practitioner you're in for a huge treat today as you always know with Bob Miller we go deep and we go technical. If you're just a person who found us on Facebook and doesn't know what you're getting into be ready for a ride because this isn't for the lightweight. We're going to go deep into genetic pathways and paryoxynitrate and some really amazing things but I promise you it'll be interesting. So I want to introduce our guest first and then I want to ask him a few basic questions and then we'll dive right in and he actually even has some slides to share because when we're dealing with this kind of stuff it's so much easier to have a visual so I'm excited that he'll be sharing that and telling us more about it. Just a little housekeeping feel free to share as we're live this will be recorded so you can find the recording here on Facebook and you can also find it on my YouTube channel just Dr. Jill Carnahan YouTube that may be a day or so tells us that it will be there as well and I am delighted to introduce my colleague and esteemed friend Dr. Bob Miller. Dr. Bob Miller is trained in a naturopathic specialty and as you know I think I've had more naturopaths on my Facebook lives than medical doctors. I always joke I was born with the heart of a naturopath because I love how we delve into the same things and the solutions there are not just drugs and surgery they're really based on a much more natural approach and I always find I learned so many things from my naturopathic friends they're some of the smartest people I know so I'm delighted to introduce Bob Miller. He actually specializes in the field of genetic specific nutrition. What you're going to love about him is he's going to dive into pathways you've probably never seen before unless you're a practitioner who's studying this stuff but it's so relevant to some of the details and if you're out there listening as a patient Bob is the kind of guy that can help you find kind of hard to to pin down pieces of your puzzle and some of the pieces that might have been missing and your doctor treated you or a nutrient like why did I react to that one so as we dive into that some of that might start to make sense. He earned his traditional degree from Trinity School of Natural Health and is board certified through the ANMA and in 1983 he opened the Tree of Life practice where he served as traditional naturopath for 27 years. For the past several years he's been engaged exclusively with functional nutritional genetic variants and related research specializing in nutritional support for those with chronic Lyme disease so any of you listening out there I know that hits a lot of you and it's sad we'll briefly talk about that at the beginning but Bob I know this is epidemic in its nature and you're in Lancaster, is that right? Yes, Lancaster. Part of Lyme country. Tell me just a little bit about how you got into functional genomics and your pathway even to naturopathic medicine. Sure, well it's an interesting story. Naturopathic traditional naturopathy is my second career. I was in electronics and in the cable TV industry and in my early 30s I came down with a very severe case of ulcerative colitis that's where the colon becomes very inflamed in your bleeding. I was in the hospital for 21 days lost half my blood then I hemorrhaged. Remember vividly the night if it wasn't sure if I was going to make it till the morning and of course the recommendation was take out the colon but you know here in Lancaster County I'm a bit of a stubborn Dutchman. So I thought there's got to be other ways. So I started digging and just became fascinated and haven't turned back yet. So I was second career and of course having an electronics background we think in schematics and pathways. So when I was introduced to genomics it just made so much sense that this is just like an electrical circuit and if you follow the electrical circuit you can go back to where the dysfunction is. So that's that's a little bit of the history. Bob I love this because I had no idea we have some real parallels of our journey. First of all I was bioengineering so all this not electrical but very same idea of pathways and that and I love that's why I love talking to you and then I think you know I had Crohn's disease which is a cousin to ulcerative colitis and I had the same thing my doctor said you're going to need drugs and surgery for the rest of your life there's no other way it's incurable. We ironically have quite a similar journey don't we? Absolutely yes. That's amazing. Well I'd love to talk about what first of all let's go really basic on what is perioxine nitrate and feel free to share whenever you want your slides and get the basics of what are we talking about here and how does that relate to disease? I'm trying to share I'm getting a message at host disabled participants yeah multiple okay I think I just corrected that see if that works. There we go. Sorry. It's like the door locks on the child's room right?  So again our subject today is functional genomics and peroxine nitrate and here's what we hope to learn today and that is you know what's functional genomics what's peroxine nitrate and then we're going to very quickly get into five pathways that peroxine nitrate might be made and of course you know the disclaimer you know we're not a geneticist here we're using functional medicine to help physicians as a clinical assistance tool and of course we're not giving any medical advice here. Now here's the basic premise and that is poor diet and environmental factors when combined with genetic variants in our DNA might cause an increase in toxic substances and then a decrease in critical nutrients and molecules needed for optimal health. So here's functional genomics it's no longer that model of treating or take this for that. So rather than suppressing a symptom we're focusing on either refining a potential nutrient deficiency or an excess of a toxic or harmful compound in the body and you know we think of genetics as where did I come from what diseases might I be susceptible to functional genomics isn't that we're looking at pathways and it gives you clues because genetics is just a pre-disposition as I like to say. So when you see these genetic mutations you use that as to you know where to put your detective hat on and dig deeper with the with labs and then as we compensate for those nutrient deficiencies or support the detoxification the body returns back to homeostasis. Now this is one of my favorite sayings this is a 3d chest game played underwater you know some people like to think oh what snip do I have and what do I need to take for that. I think we're going to find that that's you know way over simplified and it's not quite that simple thinking that you need methyl foley because you have mthfr sometimes does more harm than good and we have to be looking at this globally looking at it from a genetic epigenetic and cofactors because there's so many things that come into play. Now in the traditional naturopathic philosophy I had this picture drawn and it says when the house is burning down don't wash the windows and mow the lawn because way too many times I've seen this from practitioners they someone's really inflamed and they start trying to support methylation or trying to get the mitochondria going and it backfires because they're in such a state of inflammation. Now for those who are are new to this we're just going to go very briefly through genetics there are genes is what makes us human and just minor variations makes us unique. Now a gene is nothing but a section of DNA that provides instructions for protein synthesis. You know one of the things I'm amazed with I mean what a miracle we are in our creation we eat fats carbohydrates proteins we drink water we breathe air and we're exposed to sunlight and everything gets made from that I mean I just sit back and just marvel at the miracle of that how that all works well it's the DNA that makes the enzymes that makes that happen and you know many people have heard of SNPs and that stands for a single nucleotide polymorphism and that can make us a little bit unique and it's a variation in a gene and that SNP then can sometimes lower the function of that enzyme as we said enzymes take one substance turn it into another and if we have SNPs that's not optimal. Now this is inherited from mother and father each parent passes on one of their two sets of genes and this is how it works if a father has a gene variant and a mother has a gene variant there's a couple of options that can occur and that's why the same parents can have multiple children and their genetic patterns are quite different and here's another one on a homozygous genome how it gets passed on to the children so that's why sometimes parents can be carriers of disease both parents are fine the child has a problem. Now our genes are not our destiny I didn't coin this phrase but I love it and that is that genes load the gun environment pulls the trigger and I believe that we're being exposed to so many environmental factors that our parents and grandparents weren't exposed to and I believe that's why we're seeing such an increase in so many concerns so epigenetics means the addition to changes in the genetics and that's all the things that were exposed to the plastics the electromagnetic fields the genetically modified foods the growth hormones given to the animals the degassing of some of our materials that we use the lead that we used to put in our gas all of those things are having an impact on us and Bob I can just say a real quick comment gosh I just want to stop here because you know environmental toxicity mold is such a big deal for my patients and I really see this as the elephant in the room so that is the thing that's different from 10 years ago even for sure 50 years ago but I remember when I first started 1520 years ago I'd have a very simple case of Hashimoto's hypothyroid or some other autoimmune disease and it'd be fairly straightforward they get well fairly quickly and nowadays we have this set of very complex infectious load and toxic burden and so I don't want to interrupt you but I wanted to make sure that our listeners know this toxic load if you're wondering well why is it so much worse now why are so many more people getting sick from the virus this is part of the puzzle it's our environmental toxic load is overwhelming our natural immune defenses and we finally got to that tipping point haven't we Bob absolutely yes I concur completely and that's why I will talk about this later I'm having a conference for health professionals September 18 to 20 three days on mycotoxins and I'm like you when we see those people that are having challenges eight times out of 10 they're being exposed to mold and mycotoxins and actually I'm going to be showing you the enzyme that is up regulating that I think will be quite fascinating Bob I can't wait I'll be there and if you're a professional I will talk about this at the end we'll share links but stay tuned for September 18th through 20th because you'll want to be there Bob I wanted to just say to something else the mold is such a big deal I'm the mold expert I deal with mold all the time but even for me I'm always careful to go in with a blank slate with my patient and not assume there's any mold but over and over and over again we get to the end of the puzzle and realize oh my goodness this patient two has a mold exposure so thanks for saying the eight out of ten because it's so common absolutely now this slide is showing us that when we do have that mutation stepping in with compensatory things actually brings you back into balance and this is just a quick study on how riboflavin uh has an impact on the status of homocysteine lowering effect of folate in relation to the mthfr genotype all right to answer your question peroxinitrite this is just one of the many things that puts the house on fire so to speak now what it does there's a very important molecule called nitric oxide and we need that for circulation we'll talk about that and then a rather nasty free radical called superoxide and this has an important role in chronic inflammation immunity and aging and I'll show you how mycotoxins actually stimulate the production of peroxinitrite it's hypothesized to play a key role in various degenerative states and several analysis suggest that selenoproteins particularly the selenium dependent enzyme glutathione peroxidase they have an important role in the detoxification and in illumination I find it interesting uh the symbol for peroxinitrite is oh no love it yes uh broad spectrum antioxidants uh vitamin e melatonin they be a part in preventing the formation of peroxinitrite uh peroxinitrite formation rises 100 fold for each 10 fold increase in superoxide and nitric oxide production so what we're saying here is that superoxide generation is a potential mechanism that disrupts nitric oxide and we'll be talking about that and I've been you know talking about superoxide for probably 10 years probably in the last two to three months that I've just looked at it anew and said this is likely more significant than uh when then we realize right well it's in the sense that the theory that I've been hearing with why the antioxidants like zinc and vitamin c and um even minerals can be so powerful with viral infections is that this anti this free radical state is part of the thing that allows pathogens to proliferate absolutely yeah absolutely I mean that goes back to the traditional naturopathic philosophy 75 to 100 years ago when you know traditional folks at these people are quacks that should be in jail uh but now you know the the science is coming out and proving it to be true we're right all along yeah so nitric oxide I'm sure people have heard of it it's in the cardiovascular and nervous system it has a very short half-life and this actually won the Nobel Prize all the way back in uh 1998 nitric oxide is critical for blood pressure preventing thrombosis preventing leukocyte adhesion to vessel walls increases the flow of nutrients to critical organs and improves the efficiency of waste removal now we're going to talk about superoxide inside the cells sometimes an electron flies off combines with oxygen and that makes what's called superoxide and this superoxide has been hypothesized to be a potent key player in the aging process all right now we're going to start to geek out here so hang on to your hat here we go okay I'm going to get my drawing tool here and uh we're just going to have a great time so one of the things that we need is this nitric oxide that we spoke about and the nitric oxide is down here vasodilator and electron donor now it's quite a complex process to get there we need a substance called bh4 tetrahydroopton now things can go wrong here aluminum can suppress that with or something called the urea cycle in the kidneys that clears ammonia and these are the genes involved in that and if we have any genetic mutations or anything else that goes on that excess ammonia will also use bh4 to be cleared that's why ammonia levels are so important now we're going to talk later about nadph my favorite molecule me too yes nadph combines with bh4 oxygen and something called arginine then the enzyme NOS takes it all and makes nitric oxide unless something goes wrong after bh4 is used it turns into bh2 we can have genetic mutations in these enzymes that don't allow it to come back we're going to talk later about the nadph steel where nadph is used to actually make free radicals you'll notice there's also heme right here heme is a co-factor and there's eight steps that we need to make that heme and look who we have here glyphosate glyphosate can impact the glycine that's needed for this heme cycle wow these are people that often get hangry they're they get very upset and angry if they don't have food on a regular basis so what happens if something goes wrong here oops we make superoxide that combines with that very important nitric oxide for oh no peroxanitrite and guess what that does it further suppresses bh4 and this feedback loop just keeps going and that's why sometimes people will take l arginine thinking that oh i'm going to build my nitric oxide levels and all they do is hurt and get some viral infections so bob i want to just make some a few things things that are a ha's for me clear because i bet your listeners are saying the same thing first of all aluminum sources of aluminum super common right um i can think of obviously cooking in tinfoil aluminum um antiperspirants which is why we should only be wearing deodorants um do you know any other i mean vaccines nowadays they contain a lot of aluminum and again i am not your anti vaccine person but we have to think about load and all this i'm actually checking every patient right now with aluminum levels you would not believe the load i'm finding of aluminum so that's a really big deal ammonia um i know the gut can produce ammonia um some sorts of dysbiosis in the gut especially bacterial and parasitic um any other sources of common for ammonia in patients that you know of well sometimes eating too much protein not chewing well and plus genetic mutations yes in the urea cycle okay and then glyphosate clearly non-organic food if you're not eating organic you're going to get that on and now we know even organic california wines have traces of glyphosate so you can't be too careful with that absolutely and i forgot to point out lead lead inhibits nos and of course we had lead paint many years ago led our gasoline so if you have aluminum and lead your ability to make nitric oxide is compromised this is where people get cold hands and feet renaughts high blood pressure and we'll show later how important nitric oxide is and just arginine is not the solution i just want to reiterate that there's a way bigger pathway here that you're going to explain to us absolutely so here's the potential you know makes i'm not going to read them those are all the things that could go wrong that make it difficult uh the lead aluminum the glyphosate and here's again as we can support function okay sami acid etymothionine and methyl folate or royal jelly can actually help you make more bh4 yucca larch citrulline and alorethine can help that urea cycle interestingly which hazel and rosemary will scavenge peroxanitrite sod will help you neutralize that superoxide so you don't chew it up pomegranate green coffee bean garlic and hawthorn all support the nos enzyme so there's a lot that can go wrong in there and that's why when we do when we train our doctors on how to do this uh looking at this is one of the first things we look at because again cold hands and feet uh there it goes veins early uh hemorrhoids all of those things can be related to that nos uncoupling now i'm going to move over to iron we all know irons critical i mean we don't have iron we don't carry our oxygen life doesn't exist however something can go wrong so let's look here so there are genetic mutations that people have very high in english irish and ashkenazi jewish that caused them to over absorb iron and that was actually adaptive the irish during the potato famines if they absorbed more iron they actually did better but today we don't have famine and we're putting a lot of iron in foods so what can go wrong here again we talked about the body will make superoxide sometimes on its own we need superoxide dismutase to turn that into hydrogen peroxide however then we need something called catalase to turn that into water and oxygen we need glutathione peroxidase to turn it into water and we need triadoxin to turn it into water now glutathione and triadoxin they donate electrons and you'll hear this a lot look who's needed to keep recharging in adph is this where hydrogen can be helpful because that's a donor for either the hydrogen tabs or the inhaled would that be in this absolutely yeah right here we are so what happens is when that iron is in excess or it doesn't even have to be in excess combines with hydrogen peroxide to make what's called a hydroxyl radical which damages protein carbohydrates and DNA so here's where your hydrogen water can come in and neutralize that hydroxyl radical but we need an adph glutathione triadoxin catalase a lot can go wrong in here this is the most common thing I see and actually it's what won me the research award in 2016 at the Helsinki iLADS meeting showing that those with chronic Lyme were five times more likely to have one of the genes that would cause them to absorb more iron now one of the ironies is many times people say well I can't be absorbing more iron because I've always been told I'm anemic well of course if this is happening if this excess iron is coming down here you're making more hydroxyl radicals and then if a well-meaning practitioner says oh I'm going to make you feel better by giving you iron if this is occurring you'll actually make the person worse so what we have to do is get these pathways going then you have all the iron that you need this is called the Fenton reaction named after Dr. Fenton who discovered this in 1895 now what continues to happen here so this OH- will stimulate INOS which is another form of nitric oxide combined with again to make peroxynitrite now on this drawing we showed how this also leads to something called carbonate radical CO3 which oxidizes your DNA this is actually DNA damage that can occur so this is a very dangerous process and that's why as we said hydrogen water those tablets or the air that you breathe or hydrogen machines can be one of the most important things if someone said to me Bob you can only take one thing is the new law that you can only take one thing call it I'd have to say hydrogen water Bob I couldn't agree more if people forget they're cheap they're easy now the inhaling machines which I have in my office I use when I'm doing charts three two three days a week I use it I love it I feel so good that's a five thousand dollar machine not everybody can get that but everybody can afford the hydrogen tabs so I agree I highly recommend those as a an adjuvant therapy and it easily absolutely I was just using my hydrogen machine before the call just to make sure my brain was I love it all right I'm not going to read these but these are all the genetic mutations that can cause this to go arrive again glyphosate hydrogen water skull cap clove alphalipoic acid can support the proper use of iron SOD catalase we'll talk about this later nicotavide mononucleotide supports the production of NADPH and also copper is needed to make ceruloplasm and there's also many times mutations in the beta carotene to vitamin A and we need vitamin A and of course selenium for your glutathione peroxidase now the beauty of looking at the genomics is you can see where you need the support now EMF there's just more and more information coming out about this and I think we're going to look back someday and say oops because good intentions you know I often give the analogy you know think of asbestos what a wonderful thing because the houses didn't burn down and people didn't die but then there's that unintended consequence you know we thought lead would make our world better by making our paint better and making our gasoline more effective oops I'm afraid we're on that same path now what happens is we have membranes that store electrical potential across their membrane in the form of an iron gradient and this stores the electrical potential well what happens when we're exposed to EMF that electrical potential goes up this is a new chart we literally made days ago so here's calcium and there's a gene called CACNA1C and it's responsible for the calcium coming in now once it gets in it turns into calcium calmodulin now I've never seen a genetic mutation more accurate than this one mutations on this I've never seen anybody who didn't have it who didn't tell me that they're sensitive EMF they're more impacted by EMF and this of course creates inflammation on its own but since we're talking about the the peroxanitrite what does the EMF do creates the nitric oxide the superoxide from the EMF and makes the peroxanitrite yet another method to make inflammation inside the cell one of the things I and truly question I don't say this is a fact but Bob Navio has done some great work on the cell danger response and I have to wonder if this is not a factor involved in the cell danger response when the body's just kind of in that half shut down trying to preserve itself because inside the cell all of this is is going on so that's why you know making sure you're not sitting next to your router all day not carrying your cell phone on your body use speaker phone or earbuds not the type that you put the transmitters in your head but like those at least wired or or air ones and I often tell people that who have this is their severe problem you need to make your house very dumb do not have a smart home yes I couldn't agree more and I would say if you if you are sensitive you need to get wired internet of course I still have Wi-Fi I'm actually not as sensitive I probably should a lot of my friends just recently said Jill you know better you need to get wired so I'm probably going to be doing that but right now I have a router cover that protects me and I had a building biologist come to my condo here and check everything out and there's a meter they'll put on your body to see the voltage and then they'll check as they turn switches and check electricity my measured body meter voltage was over 3000 with the on the bed I just laid my bedroom on my bed with the normal no special lights nothing special on when I turn the master bedroom switch off it went to less than 200 that was a shock to me which means I have an appointment to get a master switch with a remote so that at night I can turn off the electricity just in my bedroom by remote and I would highly recommend if you have the resources to get a building biologist to come check your home as well when you say there's a shock to you no pun intended right exactly and Bob the funny thing was I would tell you I'm not really emf sensitive I mean I do wear bioelectric shields I protect myself I do a lot of things but I don't feel physically that ill from it like on the spot however as soon as she turned the breaker my heart stopped fluttering and went still and I didn't even notice it it wasn't like I had tech a card here or anything but I felt the physical sensation of the chain so it's very real absolutely and these teenagers who keep their cell phone under their pillow to hear if a cell by the brain there's glucose metabolism studies that show the the length of distance from your brain absolutely affects brain glucose metabolism and it's exponentially so if you have your phone right next to your head it's a very very bad situation yes I recommend getting like a battery powered alarm clock you know rather than using your cell phone people tell me yes right by my head because I use it in my alarm I think there's going to be serious unintended consequences from that so potential genomics the CACNA1C that we talked about making sure you have enough superoxide dismutase NOS is working okay and you have enough glutathione of course the epigenetics is the the EMF I'll never forget I heard a lecture from Dr. Sinatra and he said if you come to our house we have princess phones on the wall I love it so magnesium witch hazel melatonin rosemary that we talked about and superoxide dismutase and I think you know so many people are using you know they have like Netflix and they stream it to their television I think it's a good idea to have your TV wired rather than streaming it because you're exposed to so much EMF when you do that it just adds up so anything that you can do to decrease and I noticed rosemary is coming up over and over and over again I'm a 20 year 19 year breast cancer survivor that's a big one for breast cancer and there's no doubt there's a connection to this pathway because of DNA damaging effects right oh absolutely because it's taking care of that peroxide nitride now glutathione most people know about this major antioxidant it neutralizes superoxide it neutralizes hydroxyl radicals it's one of the powerhouses of the cell it regenerates vitamin c and e it's involved with detoxification aging and degeneration as we age our glutathione levels go down so we tend to think of glutathione cool the more the better and I'm sure dr jill have you ever given someone glutathione and they had a negative response to it oh yes bob and that's a that's my story and I just had a colleague just talked to us that I was like that for two years so tell us more because I'm one of those people yes well here's what happens glutathione and we just for up here we just show how it's made for fun it's you know anacetyl cysteine up here would be your glutamate your glycine and then the gss enzyme makes your reduced glutathione and then glutathione through glutathione as transferase does what's called phase two glutathione conjugation where we take out toxins and we put them in the stool or the urine and then also glutathione peroxidase neutralizes free radicals so we tend to think the more the better however some people take glutathione and they're like that is the most wonderful thing i've ever had and then other people are like i can't take that i feel horrible when i take that so let's look what happens glutathione does its job donates an electron and it becomes gssg or oxidized glutathione look what oxidized glutathione does you've heard this before combines with the oxygen to make superoxide then choose up more of your nitric oxide to make peroxynitrite oh no and then we have to use some glutathione to deal with that here's why i think nadph is so critical and not enough people are looking at it nadph donates an electron to the oxidized glutathione to take it back to the reduced that and again these are just some of the things that'll make the glutathione i'm sorry the nadph and i'll be talking later about the nadph steel so when you take glutathione and it doesn't recycle you have a problem isn't that fascinating that makes so much sense um i find that when we do give people the donors to make nadph it does help with these pathways so absolutely yeah that's why i believe that we have to learn if somebody has an nadph deficiency and support this before we start putting this in i was just going to say that first piece is often not what you think of like you said with your analogy the house and the fire and what to do first i love that because many practitioners are just this um protocolized thing where it's glutathione and liver support and detox and patients aren't ready for that if they don't have the nutrients in place and with your genetic testing people you can tell exactly what things people might need more of beforehand and the most common thing i see and those that are suffering the most they've got either nas uncoupling or fentanyl reaction along with nadph deficiency most common thing i see so we need to look at some of the enzymes that are involved in making nadph i didn't mention in that chart but there's something called nerf two and keep one that controls all the glutathione and nadph genes gsr i should mention that that is the enzyme that uses nadph so even if you have enough nadph and gsr is not working this isn't occurring double whammy is nadph deficiency and gsr problems so glyphosate again can be a problem ticket to mind mononucleotide polyarco helps nadh to nad plus grape seed extract helps the quinolidic acid move down the pathway and then a few things for nerf two milk this old broccoli seed extract to support nerf two but again if you support nerf two too quickly it can actually put people into inflammation so again sometimes it's like nerf two yes it's so important people support it and they get worse all right now this is probably the most important thing i'm going to talk about nox nadph oxidase my favorite subject and i've been talking about this for two years it's the only enzyme that its sole purpose is to make superoxide and hydrogen peroxide now we tend to think well why would it do that well again the wisdom that god put in the body is absolutely astonishing so when we're hit with a bacteria or some other pathogen the body says oh we got a problem here we need to create some superoxide hydrogen peroxide stimulates a mass cell stimulates some cytokines make some histamine and let's go in for the kill if we didn't have that we die of infection in animal studies where they take it out so this is an important process i give the analogy it's kind of like the military you want a military that protects you but you don't want a military that's turning the guns on the citizens and one of the areas that we're researching is our epigenetic factors stimulating this nox enzyme to start shooting when there isn't an enemy and that's one of the areas that we continue to uh to research now we're really going to bend your mind with this chart and what i'm going to do is i'm going to pull this one over where we can look at it just a little more closely so nox enzyme it's needed to create this cytokine storm and mass cells when when we are faced with uh with an outside invader however histamine will make it go oxalates will stimulate it excess iron will stimulate it glutamate will stimulate it smoking or particulates will stimulate it aldosterone that i'm going to speak about in a minute stimulates it homocysteine dopamine sulfite and something called mTOR stimulates it so when it gets stimulated it gets oxygen from iron and a molecule from nad or a electron from nadph now keep in mind we just learned we need nadph for nitric oxide we need nadph for glutathione we need nadph for thryodoxin so that's why I coined the phrase the nadph steel this nadph is being used excessively to create this storm so then it creates the mass cells and here's mycotoxins here's Lyme disease emf xenobotics the mass cells will then create cytokines stimulate these interleukins tumor necrosis factors and histamine all good things when we're fighting a battle and we have somebody to take care of to take out when it's running amok we have a problem now this is some of the latest research that i think is very exciting we have something in the body called renin and that stimulates angiotensin one the ace enzyme makes angiotensin two that stimulates the aldosterone that then stimulates the dox enzyme and of course we know this is what's behind hypertension there's an enzyme called h-mox that calms this down when people have mutations in h-mox they can't calm this down now there's an enzyme called ace two that takes these pro-inflammatory vasoconstrictive molecules and turns them into angiotensin 1-7 which is vasodilative in anti-inflammatory as a side note COVID-19 comes in using ace two i was gonna say i know where you're going with this because a lot of the side effects we see are from that vasoconstriction correct absolutely so this angiotensin two then stimulates interleukin six which is behind the cytokine storm yes interleukin six stimulates NOx and it goes around but here's what's really exciting just presented this to my doctors last night in a webinar histamine mast cells and peroxanitrite remember whenever you have superoxide you're going to get peroxanitrite hold onto your hat stimulate renin wow and here we have a positive loop that just feeds upon itself high glucose peroxanitrite histamine conflicting information on dopamine but also testosterone stimulate the renin you know this might be one of the mechanisms behind the cytokine storm and so for example if something kicks this off like if a child with you know gets a strep infection and then goes pans pandas or as you said earlier we're not anti-vaxxers but if you get aluminum and the aluminum stimulates this this could be one of the mechanisms that causes that to feed upon itself now what's interesting is that nitric oxide in oxytocin calm down NOx and mast cells and if your nitric oxides being destroyed we don't have it and of course oxytocin the love hormone so go hug somebody or at least to hold your cat or your dog okay we've had social isolation for two months and starting to come back but we're not frequently hugging one another hugging is one of the main mechanisms that's not breastfeeding or sexual that increases oxytocin i've said for months i've said yes i agree with what's happening we need to take precautions but we're not thinking about the fact that social isolation is a huge risk factor for immune dysfunction and now you're telling me it's a huge risk factor because you have less oxytocin production for the blocking of this enzyme absolutely so i'm really excited about this pathway and and clearly there's way too many genes to go in here but these are all the genetic mutations that could contribute to that here's all the epigenetics that could combine to it and then luteolin pea baswellia can calm down the mast cells nettle leaf quercetin can support the histamine response methylation supportive elevated homocysteine and as we said mold remediation so important air purifiers superoxide dismutase we spoke about those before that can support the uh that can support the NOS enzyme so i believe this might be behind why we're seeing such a rise in autism dr. Thea Hardee's from Tufts University believes that mast cells are behind stimulating the hypothalamus that may not be the whole answer but there's the potential that that could be an issue and needs to be uh to be researched so i think for anyone who's doing functional medicine trying to determine if any of these factors is up regulating this is uh critical and now you can see why i call it the 3d chess game. Bob that is a key go back one more time to that slide i want to hear your your contact we have a minute and this is so key i just want to hone in on this i'm having about 101 ahas now as i think about this i think about what we just went through with pandemic and have ongoing and the types of risk people have whether it's predisposition diabetes heart disease has to do with a lot of these pathways and the same cytokine pathway is active with lipopolysaccharide endotoxemia which is a long technical word for leaky gut when you have bacterial coatings leaking into the immune system they stimulate the same isle six pathway as well and i feel like a lot of the risk factors we're seeing with heart disease diabetes um age they're more likely to have some of these things i think already primed and then you just gave us a list on that other slide of uh the allergies and mycotoxins and Lyme disease and these are all likely to lead to more inflammatory states more risk of infection and probably more risk of the virus being an issue. Absolutely and that's why sometimes bodybuilders are those who are trying their best to keep their testosterone and stimulate their mTOR maybe at the highest risk right now. Wow. Yes now one of the things we just heard was that there was a drug that was discovered in England that seems to get people out of the cytokine storm. We immediately researched this and what we found is it inhibits the NOx enzyme. Wow. Yes. Wow. I think you sent me that study. I remember us talking back and forth um and if not I would love to see the research that sounds so familiar because of pereoxynitrate and the cytokine storm because really this is such kind of like the cell danger response it's almost like we're all looking in our areas of the same thing and describing it but it all comes together with such cohesiveness because it makes sense and as we went in the very beginning to pull it back together for a practical takeaway otherwise this is overwhelming. First of all if you can get with the functionalists and doctors especially one that's been trained by Bob they can help you walk through these pathways and I know Bob does consults himself and but mainly do you mostly teach doctors Bob do you do? Yeah mostly we we have online certifications for the doctors and I do a lot of one-on-ones with doctors where they'll they're like Bob I need help with this and I'll you know walk them through it to give them the the guidance they need and I can just say if someone is a doctor and they're interested in the software there's the website dnsupplementation.com Yvonne Lucasi is the executive director she can help and if someone wants to contact our office there we are Tree of Life Health there's our phone number and our and our website and then also there'll be links there to our conference September 18 to 20 and I have an online certification course for doctors that walks them through like we have probably around 30 hours of instruction that step by step takes them through that NOS uncoupling the glutathione the the the mass cell activation so if doctors want to learn this we have a resource for them to to learn this. Excellent and Bob I'm going to share this with my practitioner list and I'm going to ask you guys if you're listening if you have a doctor you know you know I'm on Facebook or another medical provider or someone who is in the functional medicine realm please share this information share this lecture with them I think everybody should get to know Bob Miller he is one of the brightest stars out there and what I love about Bob is you can tell he's brilliant I love talking pathways but even more than that he's got a really great heart he really cares about people he cares about finding solutions and I just every single time we talk Bob I learned something new I am so grateful for minds like yours and hearts like yours that are out there just continuing to do the science because this is the kind of thing that really pulls it together and as we both know this is the only real thing that's going to change our system a drug itself might be a potential solution but a drug is not going to help the hundred percent of the population because of these genetic variations so we have to have solutions that are more personalized. Absolutely and let me also say I think the world is very fortunate that you're out there leading the way and helping educate so many doctors I think when the books on functional medicine will be written there'll be a large part talking about Dr. Carnahan and you know you have a beautiful heart as well that you want to help people get well and so the utmost respect and admiration for you. Thank you so much Bob this has been a real treat please be sure and share I'm going to include in the links the things that you saw on the slide as well so if you missed it you can also watch this again but I'll be sure and include that all thank you


Hey, this is Brett, and this 2012 Ford Mustang Roush conversion package, Stage 3, is stock number 12879Z. We're here at Summit Automotive in Fond du Lac, Wisconsin, near New and use sports car headquarters. This 2012 Ford Mustang Roush Stage 3 conversion has the 5-liter V8 supercharged engine that puts out 540 horsepower. This car has been fully-safetyed and inspected by our service shop per the state of Wisconsin inspection process. It has a fresh oil and filter change, all the fluids have been checked and topped off. And this car is 100% ready to go. We're going to go all the way around in this video, inside, start it up, take a look under the hood, go over all the options on it as well. In-git silver is the color. We shoot all of our videos in 4K, so if you have HD capabilities on your computer, tablet, smartphone, or television, I highly recommend turning them on right now, because it is your best way to check out the quality, condition, options, and cleanliness of the vehicle before seeing it in person. And if you like the video and how we do things here at Summit Automotive, consider clicking the subscribe button to our YouTube channel in the lower right-hand part of the screen. And then click the bell notifications, you'll get updates every time we do videos here at Summit Automotive. This one comes with the Roush chromed alloy rims. These are 20-inch rims, and it has Sumitomo, HTR Z3 tires. These are 275, 35, ZR20s in the front. And I would say these tires have roughly about half the tread left on them. You get these slotted rotors and the Roush calipers. Front fender is in excellent condition, I didn't see any major dents or dings on there. Front bumper and lower valance are in really nice shape. You can see it's never been drilled into on the front bumper. It does come with the HID headlamps. And the hood is in excellent shape as well. I didn't see any dents or dings on there. Passenger side front fender is in really nice condition too. And the passenger side rim, no major scuffs or scrapes on there. As you go down this side of the car, take note of how clean the body is, how reflective and mirror like the paint is on this 2012 Roush Stage 3. We take these HD videos so if you are far away, or even if you're close by, you just cannot make the trip down, but you're still interested in purchasing the car. You can see the car, hear the car, and have confidence in the vehicle that you're looking at before you even get here, so that when you do get here, there's absolutely no surprises and you can make a smart and informed buying decision from wherever you're at. And if this video helps you make the buying decision, let your salesman know that you saw the video, that it was helpful, and that Brett sent you. Has these slotted rotors in back as well. And there you get a better view of how much tread is on those tires. Underbody is pretty clean on this car. And I did want to show you the Roush sticker, so this is a Stage 3 2012. In 2012, they made 365 Stage 3s. This is your serial number on this car, so 12-0-1-6-7 is the Roush serial number for this car. Pass and receipt is nice and clean. And once again, they made 365 Stage 3 coupes in the United States. Coming around to the back, the rear bumper and lower valance are in excellent shape. I didn't see any dents, stings, scuffs, or scrapes back here. You get that matte black finish on the rear of the trunk, 540 horsepower. Stage 3 logo. Take a look inside the trunk here. Very clean back here. And this one comes with a spare tire. Really like that deck lid spoiler on here. The trunk lid itself is in excellent condition. I didn't see any dents or dings on there. And coming around to the driver's side of the car, just as clean as that passenger side. No major dents or dings on the rear quarter. And for full disclosure, this back rim is in fantastic condition as well. Down the rest of this side of the car, the doors look really good. I didn't see any dents. I didn't see any dings. Really nice. Has the power mirrors with the blind spot mirrors. This one has the black leather interior. There are no rips or tears on the seats. They are in very nice condition.  Black seats are in excellent condition as well. And it does come with the latch child safety system back there. If you want to try and get car seats back there, that is definitely up to you. We'll hop inside, check out the miles, the radio, and everything that this car has to offer on the interior. And then we're going to start it up and take a look under the hood. And check out everything that this car has, and just take a look under the hood. Listen to it as well. This car has 20,904 miles, and yes, we will be putting some gas in this car right after this video. You can see the instrument cluster, the special roush instrument cluster, looks really good. Comes with the leather wrap steering wheel, audio controls on the right, information center controls on the left. Comes with the AM, FM, and serious satellite radio capabilities, CD player, climate controls, stability control, that's your obviously your hazard lights and your trunk popper, sync so you can connect it to your Bluetooth cell phone. And then you get the roush stage three badge right there as well. So 540 horsepower, 465 foot pounds of torque. You get the roush shifter on here as well. And then you get the roush plate on the center console opener there. Ambient lighting inside with the cup holders, passenger side format and seat are in excellent condition. This car smells very clean inside, I don't think it's ever been smoked in. And the headliner is in fantastic condition as well. You do get map lights up there and home link buttons for your garage door security systems and lighting systems. All right, we'll start it up, listen to that exhaust and then take a look under the hood. Sounds really good, no check engine lights or anything like that. And like I said, we're going to be putting some fuel in this car right after the video. Let's first go take a listen to that exhaust. This part of the conversion package is the roush exhaust on here. Sounds really good. It's one of my favorite aftermarket exhausts on these 5L is the roush exhaust. And I would personally like to thank you for checking out the video today and hopefully from this HD video, you've been able to verify the quality, condition, options and cleanliness of this car all the way around inside and out. Under the hood, we have the 5L V8 engine, the roush, supercharger on there. Engine base is very clean, runs very smooth. Once again, this car has been fully safe and inspected by our service shop as a fresh oil and filter change. All the fluids have been checked and topped off and this car is 100% ready to go. There is your stage 3 plate right there. You also get one over here. You can see it was built by Matthew Czensinski right there. And then your emission sticker is right there. And like I said, this car is 100% ready to go. I would highly recommend this 2012 Ford Mustang Roush Stage 3 conversion in Inget Silver Metallic from a quality and condition standpoint. Really nice car. And to see more pictures of this car, we're going to run our other 450 new and used cars, trucks, SUVs, minivans, wranglers, halftones, circular tons, one-tons, you name it. We got it. Mustangs, Corvettes, Challengers, Chargers, GT500s. You name it. We got it. Go to that website right there, summitauto.com. You can find descriptions of every single vehicle from two locations all at summitauto.com. And if you'd like to check out more HD videos, you can go to youtube.com slash summitauto. Remember to like, subscribe, and share on this video and all the videos that you see there. Click the bell notifications. You'll get updates on the videos we do each and every day here at Summit Auto. In fact, in a second you'll see a link to subscribe to our YouTube channel on the upper left. A link to more Mustang videos like this one on the upper right. A link to this vehicle on our website on the lower left. And a link to one of our latest YouTube videos on the lower right. Click those. Check us out. I'm super excited to help you with this Ultra Clean 2012 Ford Mustang Roche Stage 3 in Inget Silver Metallic. Thanks again for checking out the video. Remember to like, subscribe, and share.