Our next speaker, sorry, our next speaker is Amy Harmon from the New York Times and she will be talking about the public place in personal genomics. Thank you for the introduction and thank you all for being here for this historic event which is also known as my first PowerPoint presentation. I'm a writer. I don't do PowerPoint. So we'll see how it goes. Please be patient. It's an experiment. You guys are used to those, right? Experiments. Talking to scientists. So, okay. I'm going to talk about the public place in personal genomics. So naturally my first slide is of two women in a nail salon getting a pedicure. So if you're wondering why, this is a picture of, oh I know, I have to do, this is also my first use of one of these things. This is a picture of Deb Lindner on the right and her mother Joan and they are getting a pedicure because Deb has inherited Joan's BRCA1 mutation and this is how she wanted to spend the afternoon the day before she went to get prophylaxis mastectomy. I'm going to come back to Deb in her story which I think illuminates both the virtues of the work you do and some of the challenges we all have going forward. But first I want to back up for a minute and address a question that may be in some of your minds since it definitely was in mine as I was preparing for this talk and that is why am I here? Okay. Let's see. This is my first. What do I do? Oh, do I have the wrong one? Okay. The PC one, not the Mac one. See, I'm learning. Okay. So this is a list of some of the speakers at this event, many of whom you've already heard from. I took this from an email that Eric sent around as he was organizing it a few months ago. So you can see if you read down the list that one of these things is not like the other as they say on Sesame Street. So here we have like, you know, the MD, PhD, MD, PhD, MD, PhD, JD. So Eric referred to them this morning as some of the great minds and genomics. And here I am, a lowly newspaper reporter. And not even a real science reporter. I have a BA in American culture. I work for the national staff of the New York Times, not the Science Times, although I am an avid reader of the Science Times. When I write about the social impact of science, which I like to do, I really rely on people like you to explain the science part. I thought of a couple of reasons why I might have been invited. One reason I thought was maybe I was invited because other reporters, like my colleague Nicholas Wade, have written somewhat critically about the genome's anniversary. A decade later, genetic map used few new cures he wrote, and that was one of two parts. And so maybe, NHGRI was looking for a journalist who seemed like she might be a bit more sympathetic to its cause. I didn't actually ask Eric that, but it crossed my mind. I thought that maybe there was a sense of obligation to give a nod to the ethical and social and legal issues on the program, although in my somewhat limited experience at scientific conferences, the LC session often seems like the cue to head to the bar.  And with all due respect to Amy, this presentation was great, and we should all, and I'm gratified to see you all here, but I just thought maybe that was something they needed to do by inviting me. Also, I thought maybe they just wanted me to write something about this 50-new strategic plan, so maybe some good press could help them.  I thought, okay, I'll take Eric at his word. Maybe they really want what he called in his email a community perspective. That was what I was asked to provide. Maybe they want to see what an average reporter like me has learned about the impact of their work on average Americans, because these scientists are often their labs working really hard, and they just don't get to see that for themselves very much. So I thought, all right, maybe, maybe I could make a genuine contribution here. Okay, geneticists. Okay, PhDs and MDs and MD-PhDs.  I'm going to show you some of these pictures, like this one of Samantha Napier and Tegan Lane, who are not related but share a deletion on the short arm of their 16th chromosome that was only deciphered a few years ago with technology that grew out of the Human Genome Project. I'm going to show you these pictures, and then I am going to respectfully suggest that you need to get out of your labs and talk to people more yourself. Not just the people who you've directly impacted, but those who you might impact, pretty much means all of us, I think. Because I have to tell you that there was another question in my mind as I was pondering the invitation to come here today, and that is, why bother? As much as I was personally honored to be asked, this is not my job. The New York Times does not pay me to learn PowerPoint so I can try to communicate with scientists. They pay me to write stories, and they are calling me during the breaks and asking, what have I done for them lately? But there was sort of a selfish, pragmatic reason for me to do this because the kind of stories I like to write depend on a public that is not totally alienated from science and scientists. And I really worry that if this decade does not bring more meaningful and compelling communications between you and the public, that you jeopardize the future of this important work and also the future source of my favorite kind of stories. So I'm here. I'm here both to tell you about some of the personal genomics that I've come across, the personal genomic stories that I've come across, and to try to coax you to tell your own to a broader audience. Many of the speakers here today have outlined a huge amount of scientific work that needs to be done, but I would argue that communicating about this work to your friends and neighbors and local high school students and local journalists should be an equal priority. And maybe, maybe that is why I really was invited, because you knew I'd have something to say along these lines, in which case I'm happy to oblige. So let me go back a minute to these girls, Tagan and Samantha. They live on the opposite ends of Kentucky. A genetic counselor who saw both of them put their parents in touch, and this picture was taken when the two families met at an amusement park in the middle of the state, because even though there is no treatment for Samantha and Tagan's disorder, which includes digestive problems, learning difficulties, head-banging behavior, their parents felt they shared something important. It's like meeting family, Samantha's older sister said on this day, three years ago last summer. The mothers are still in touch and email frequently. What is so striking to me, what draws me to write about this stuff again and again, is how intimately genomics research affects individuals and families. Deb Lindner and her mother, from the pedicure slide, not from this slide, I should really have note to self for future PowerPoint presentations, the slides in a better order, Deb Lindner and her mother really argued over whether she should get that mastectomy. Deb was 33, she had a boyfriend, but she was not married, and her mother felt it was too drastic a measure to take at that time. And Deb told her mother, her mother who was a breast cancer survivor who Deb had watched go through brutal chemotherapy when Deb was a teenager, she said, I have this amazing gift of knowing my risk. You don't know what you would have done if you had the same gift as me. It's intense stuff. Deb refers to having a BRCA1 mutation as a great sorter of men. She had a boyfriend when she got her surgery, but they broke up soon after. He ended up telling her he couldn't deal with it. Now she has a husband who told her after she gave him a certain New York Times article to read after their second date that he thought she was the coolest person he had ever met because of what she had done. So this is Katie Moser, who I met shortly after she tested positive for the mutation that causes Huntington's disease at age 24. Now historically most people at risk of Huntington's have chosen not to get tested because if you're positive you're facing a really, really terrible fate. And for anyone who doesn't know, Huntington's symptoms typically start at middle age and you gradually lose your ability to walk, talk, move, eat, think. Katie is one of a growing number of young people at risk of Huntington's who are deciding to get tested. In large part I think because of the beginning of a more enlightened view of genetics in our society. We now have a law that prohibits discrimination based on genetic information. There is a lessening of stigma. And Katie went through a very tough time for a while after testing positive and I was with her during that time, but she said she never regretted it. She wanted to know and now she's working tirelessly to raise money for research for a cure before she gets sick. And she's also right now in the middle of doing pre-implantation genetic diagnosis so that she can have a child who will not be at risk of Huntington's. So people take genomics personally. Sometimes for very good reasons as we've talked about. Sometimes I think also for sort of irrational reasons. I think it's hard for some people to distinguish between the more innocuous things you can learn from your genetics and the more profound ones. But for whatever reason, our DNA is bound up in our identity. People tend to regard it as the very essence of who they are. And this slide is just a slide that shows, there's one recent study that says Americans are concerned about the privacy of their genetic information. It's nothing new. Kathy Hudson of the NIH has been measuring this and talking about this for years. But I really think that it is in this personal nature of DNA that your challenge lies because the stakes of not communicating the significance of your work are getting higher. This is Carletta Tlusi. She is a council member of the Havasupae Indian tribe. She lived at the bottom of the Grand Canyon, which I got to visit with a helicopter when they were in the middle sort of on the cusp of a settlement that they received from Arizona State University of several hundred thousand dollars last year. It was a long drawn out story, but a genetics researcher at ASU in the early 90s took blood samples for what the tribe understood to be diabetes research and later found out that she had branched into research on their geographic origins and other diseases that they said that they would never have agreed to had they been asked. Havasupae and many other Native American tribes have refused to participate in genetics research for many years. Now, some scientists I've talked to here that have a Havasupae story and they kind of dismiss it as a unique case. They say, well, that was a long time ago. It was a single researcher dealing with an uneducated population at the bottom of the Grand Canyon and also the whole concept of informed consent was sort of in its genesis, informed consent for genetic research hasn't been sort of fully formed yet. But here is a picture of a mother in Texas and this was just last year and she found out that the standard heel prick of blood taken from her newborn that she was told was taken just to make sure that her daughter was healthy was stored in the state database and was being used for different kinds of disease research. And this is what she said when I interviewed her last year. Her name is Andrea Bellino. She's a legal aid lawyer. She said, the irony is if you had asked me I probably would have consented. I would love for there to be a cure for breast cancer which runs in my family. I would love for there to be a cure for diabetes. The way they went about it just made me distrustful. And so she was instrumental in this lawsuit against the state health agency and all of these blood spots that were being used were in the state of AIDS for its millions of them were just destroyed. So, you know, you guys want a one million genomes project. One million genomes. That is huge, right? And you want a budget to support it. And I was glad to see a line in the new strategic plan being introduced today that notes the importance of public education in this massive effort. I cut and pasted it here. Not having the PowerPoint skills to actually take the PDF file and put it in the slide. But I have to say that my editor would not approve of this use of passive tense. Education programs are needed. This is from the nature. So it's spelled in this like English way because it's from the nature article. But education programs are needed to promote lifelong public understanding and awareness of the role of genomics and human health in other areas. Okay, that sounds good. That sounds good. But I have to tell you, in case you haven't noticed, you guys are busy. It is hard to get you on the phone. Your funding depends on publishing papers and not on talking to people like me or on educating friends and neighbors and high school students about personal genomics. So I just want to take this opportunity to really pose the question, how will that public education happen? Who will do it? Is it possible that the NHGRI could require it as part of its grants to investigators? It's just a question, but there's no incentive for you. It's just frustrating to me because every time I talk to a scientist, I am aware that I'm taking his or her a very valuable time. And it just seems like if you really believe in it, they should be paid to do it somehow. You should have to do it. So anyway, since so much of your energy does go into publishing papers and so much of your career depends on it, I wonder also if you might do more in this decade to publish those papers in journals where average citizens could actually read them without paying $15, $30, sometimes $50 for each one. Now, I don't know if anyone in this room has ever run into a screen like this because you all have institutional subscriptions to all of these major journals and you probably just, you can sort of surf them like I surf the web, but I, the Times has fallen on some hard times of late and I don't have a subscription to all of these journals. Maybe Nicholas Wade does. So I run into this all the time. How do I get access? Well, I have to pay. This article, I don't know if you can see, it's called Making Data Maximally Available. So, and this is what happens to my readers, right? So I try to be conscientious and I put links to your papers in my stories. My stories, as I said, I'm not really a science writer. I try to write these human stories, but I want people to be able to get more information about the science.  We want people to, you know, we want to be as open as possible. We want people to be linked to other information, but that's what they get. That's what they get. Now, I understand that these science and nature and self traditionally be considered the prestigious places to publish and your jobs and your tenure and your grants depend on publishing in the most prestigious places. I get it. But if you care about communicating your results to the public, as well as to each other, I don't really see how you can justify it. And I think that Harold Varmus, who I was here today, he may not be here now, former NIH director, now NCI director, had that in mind when he co-founded the Open Access Journal, Public Library of Science. And there are other journals, too, that allow taxpayers to read about the results of the research that they are paying for without paying again. So, you know, again, you invited me, so I think I'm allowed to make these suggestions. But I just think it would be nice if scientists would take advantage of these Open Access Journals and it would be nice NIH leaders who control their funding if you would give them an incentive to do that. Okay, I just want to reiterate the title of this paper, Making Data Maximally Available. Okay, so switching gears slightly here. One of the most riveting personal impacts of genomics research that I have had the privilege of reporting on over the last couple of years is the testing of a molecularly targeted drug for melanoma, which you heard a little bit about from Linda Chin already. The drug still doesn't have a name. It was developed by a small biotech company called Plexicon and acquired by Roche, a pharmaceutical company. It grew out of the discovery that the BRAF gene is mutated in half of melanoma tumors, which in turn grew directly out of the Human Genome Project. And this drug Phase 3 randomized trial was just stopped a few weeks ago because the drug had proven to extend lives beyond the standard chemotherapy, which honestly wasn't that hard since the standard chemotherapy doesn't do anything. So this is Kerry Adams, a young woman in Oklahoma City who was diagnosed with metastatic melanoma, which is typically fatal within nine months. When her tumor tested positive for the BRAF mutation, she joined a clinical trial for the Plexicon drug, and I'm just going to try to do this, which is another PowerPoint thing that I've sort of... Oops, that I may have failed that, but how do I get... How do I... I'm going to try to play a one-minute video for you. Yes. Thank you. Okay. Take the other mouse. Go to the bottom of the screen. Oh, it's not really... It's being weird. Okay. Okay. We'll see if I can play you this video. Maybe make it bigger. Oh, no, play. Oh, there's no sound. The first few times this just took me, you know, 30 minutes to take them all. By the time she began taking the drug a year later, Roche had reworked the formula. She was given a more potent dose. And for two months, Ms. Adams took 28 pills daily. Then she went to her doctor for the first CAT scan results. And he comes in and he says, okay, I think I've got some really good news for you. And I was like, okay, what is it? You know, like, just so excited. You know, he said that the scans showed a significant shrinkage in the size of all of the lesions. You know, he said, I think we found the right drug for you. I think, you know, that we can look at this long term. She was not alone. Across the country, the Phase 1 PLX 4032 patients were responding. Would the responder shared in common with the... You can watch that video on the time to site. I just wanted to give you a little quick flavor. We made this, it ran in conjunction with some of the stories that I wrote on this clinical trial. And now I have to do this. Ideally I would integrate the video into the PowerPoint. I realize that. So I'm learning. Next time. Oh no, now we're at the beginning. Okay, we're going to go through these slides. So these are just a couple more people, pictures of people. Because I'm trying to show you pictures of people on the trial. So that's Kerry. That's Randy Williams. He is a construction worker in Arkansas. This is Mark Bunting, an airline pilot in near Salt Lake City and his family. So this BRAF story doesn't have a really happy ending, at least not yet. It's after an average about seven months patients relapse. But the hope is that that is a model that people responded and that the right people responded to the right drug and that it's rational and that this model can be replicated. And researchers are using the tumor samples of several, including Mark, several samples from patients who have relapsed to try to look at them and understand what's the new driver. And if they can figure that out, then maybe they can find a similar drug that can hopefully block it in a similar way. And the first two papers were actually already, I mean, talking about Linda mentioned, you know, how quickly this is happening compared to how it happened in the past. But so the papers on the resistance mechanism, or potential resistance mechanism were published in nature in December. So that work is moving along. Of course, since they were published in nature, the patients themselves, if they are alive and their families can't actually read the papers without registering and paying for them. So I can't help pointing that out. But I am these stories. I wrote a series of five stories on this clinical trial over the course of a year. And I really, I must just, you guys all do acknowledgment screens, so I just want to say that I am grateful to many of the MDs, PhDs and MD-PhDs who spent a lot of time with me explaining the finer points of cancer genetics and making it possible for me to try to convey the impact of this bit of genomics research to the readers of the times. Okay. Now, we're back to this. And I just, I wanted to just point out that I'm actually here on this slide. You can't really, you see my elbow? So I was forced to get a pedicure too that day in order to really do my job as a reporter. And I was with Deb the day before her. And that stuck to me in the day of it. And now Deb and I do panels together. Sometimes we speak on this issue. And she often reminds me that only 30,000 of an estimated 250,000 women who carry the BRCA1 and 2 mutations have actually been tested for them. Many don't know they're at risk. And I just, if that's the case for this sort of extraordinarily well-known risk genes, risk genes, it seems like there's clearly a long way to go to educate the public about personal genomics. And just as a final note, I sometimes hear that scientists think that they can't talk to the public because they don't know how. But you all have stories. I've heard some great ones today. I think you underestimate yourselves on that front. You're passionate and excited about what you're doing and only you can inspire that passion in the public. And if I could learn to make a PowerPoint presentation to talk to you elite scientists, I am quite sure that you can learn to talk to regular people. I'll do better next time, and maybe you will too.


Hey everyone! Welcome back to Six Sister Stuff. Today we're sharing with you three easy freezer meals to make your mornings a little bit smoother. So my name is Kristen. I'm Camille. And today we're sharing with you three easy freezer meals because really mornings are crazy. You're insane. I love kids and getting them out the door. It's crazy. And I don't like to make my kids eat cereal every single morning.  Exactly. Because mornings are stressful enough so let's instead of making a hot breakfast like have it all ready to go pull it out of the freezer, heat it in the microwave, breakfast is done. Good. All right let's get started. Okay so the first one we're going to make today is actually one of the most popular recipes on our blog. They're called scrambled egg muffins because you make them in a muffin tin but basically it's scrambled eggs with whatever you want to add to it. So I'm going to show you the quick and easy way to do this. I'm just taking some cooking spray. I've got a muffin tin here with 12 cavities I guess. We're just going to spray each one and you want to make sure that you get the spray in the entire cup in the entire tin so that it doesn't stick as you pull them out. You don't want that. No because then it comes out all messy. Yes. Then I'm just using large eggs. I've got 12 here. Do you want to help me crack them? Yes I'll crack them. We're going to crack one in each muffin tin. Now if you have a lot of people in your family you can easily make two of these right and cook them at the same time. You can make as many of these as you want. This is a fun one too to get your kids help with. I mean if they can crack an egg they're good. If you wanted to you could also scramble the eggs in a bowl but this is just an easy shortcut that we're going to show you. It's one less dish that you have to do. I might do it without my children because they'd be eating egg shells for breakfast. Right? Okay so once you get all of them cracked the rest is completely up to you. Whatever you want to add to them we're going to keep it simple today. Just do some ham and cheese but before we do that you just want to take a whisk and kind of whisk the egg yolk in each one. There we go. Yeah these are kind of large eggs. I would probably do a medium sized egg just so you don't mess up the muffin tin it's a little it's going to be a little messy but that's okay. And if you if you like the egg yolk to be a little bit more runny then just leave it whole. Yeah totally leave it as is. You could also use a fork if you don't have a whisk that would work perfectly too. Oh that's a good idea. So just break the yolk in each one give it a little stir. A little swirl. Yep and you'll be good to go. Now seasonings maybe? Yeah totally so whatever seasonings you want to do I keep it simple just do a little bit of salt and pepper on each one and the great thing is too after these cook you can always add more seasonings like if you need more salt and pepper if you need a little garlic powder or whatever you want to do. Okay the next thing that I add I like to add is any type of protein so I mean extra protein in the morning it's awesome. I just bought this pre-cooked ham whatever protein you do you just want to make sure it's pre-cooked so if you're going to do sausage or bacon make sure you cook it first and then you can add it to these egg cups because it's not going to have enough time to fully cook. If you have raw meat in there. Sometimes I like to take my like leftover turkey or chicken and put it in there too. I love chicken in my eggs. It's chicken and egg but it works. I like it. It's a great lean protein great way to start the day. Okay the other thing I like to add is just cheese. Oh sorry I can do that. Kind of scramble eggs without cheese. Right. But from here it really is whatever you want to add and this is where I let my kids join in. Nice. Because they can do we like to do peppers we like to do zucchini we'll do tomatoes. I like mushrooms.  So once you get it all done kind of give it a little mix kind of push that cheese down so it can mix with the eggs a little bit more. Nice. And then you're just going to preheat your oven to 350 degrees. These are going to cook for about 20 to 25 minutes. Perfect. Oh and also like if you don't like the yolks you can also do two egg whites in place of it too. Yeah. Sometimes I like to just do egg whites in the morning. That works great. Okay those are ready to go. Let's put them in. All right so these have just come out of the oven they of couple minutes ago I'm just going to kind of show you how I get one out. So these are ready to eat right now or you can just put them straight in the freezer from this I would let them cool down all the way first before putting them in before putting them in but I do the same thing just fill a big freezer bag like a gallon sized zip lock bag and put these inside and then pull out one or two or three as needed. Perfect. And just heat it up. Yeah just heat it up in the microwave like I love to put salsa on top of mine when I eat it after I reheat it just throw on some salsa you can do some extra cheese. Nice. Want to know my favorite thing on it? Yeah. Cottage cheese. What? I know cottage cheese and eggs. It's so good. Okay I'm learning so many new combos chicken and eggs cottage cheese. I eat a lot of eggs. Awesome. All right all right so the second recipe is instant pot oatmeal. Now you can make oatmeal on the stove and this will still work I just love making it in my instant pot and then the thing I bet you didn't know is that you can freeze oatmeal. I didn't know that. No. So I also didn't know you can make it an instant pot so easily you just told me what it was I was like what? It's my favorite it's my favorite so I'm going to show you what I do. So you're first going to take I like to do two cups of oatmeal okay um to four cups of water so that's the ratio so if you have four cups of oatmeal you're going to need eight cups of water so we're just going to do two today because that will fill up our whole muffin tin exactly so we're going two cups here and then we are all already measured out our four cups of water so let's pour that in oh I missed I missed we're not professional here all right you just want to make sure that you mix the oatmeal so every part of oatmeal is touching water and that is it okay that's I know right so we're just gonna put the lid on now we're going to make sure our little knob is turned to ceiling not venting all right so then we're going to push the manual button or if you have a duo it's a it's the pressure cook button so we're going to do manual and then we're going to go all the way down to one minute so we're just going to cook it for one minute that is it so once you set it for one minute you're going to just wait a few seconds and then it's going to push and then it's going to stay on and you just walk away yeah I used to not know that that's what on meant that it like was coming to pressure I was like no don't be on cook but it is yes it's working all right we'll let this cook and then we'll come back okay so almost finished take off that let's open it up there we go nice so there's still a little bit water can we just mix that in yeah we'll just mix that in and then it will all just be the perfect texture as you do it yeah look at that yeah that's awesome okay so my trick to freezing it can is that you're going to put it in these little cupcake trays and just freeze it just like that okay cool so I like to get like a little um third cup or fourth cup and just make it easy to just pop it right in there so what are these these are like silicone yeah this is a new hand that I had that is so cool I know so then when it's done you just like it just pops it right out so you don't even have to spray this no because it's nonstick or nope it's the silicone and it pops it yep cool so with these I kind of just here I'll let you do it just pat them down really good and then I also I just put the toppings on it right now while it's hot so the brown sugar will mix in so it melts in yes and you can really add whatever you like to put on top you can I mean from raisins to raisins to I love raisins and cinnamon right it's so good but today we're just going to add a brown sugar and a little bit of I will get started on that okay so then I kind of press the nuts down a little bit okay and then I actually just stick it in the freezer just like this even when it's hot even when it's hot I just throw it right in so I wait a few hours and then we'll pull it out okay okay awesome stick in the freezer all right so once they are all frozen ready to go I just popped them out of the things and they are like perfect little circles I love it I love it so then I just put them in a freezer bag now you can do individual bags or you can just put them all in so this is how you warm them up so I do about two or three for me and I put them in a bowl add just a little bit of milk and then I microwave it by minute increments to see how long it will take to melt them and get them all ready so super easy perfect breakfast if you have crazy crazy mornings so our last recipe we're going to show you how to freeze waffles now I wouldn't suggest freezing pancakes like you can you can but when you cook them again lots of times they're soggy they're soggy yeah that's not my favorite so I actually found this cute little waffle iron it's just mini and it makes single servings yes but it makes them the perfect size that you can stick them in the toaster oven yep or toaster yeah and they come out perfect so I make a lot of these and then I freeze them it's like homemade a go waffles yes but they taste so much better and they're better for you so yes so now you can make homemade waffle mix yeah but one of my favorites is the kodiak cakes I don't know if you guys have seen that there's protein in it and so I feel like yeah it's a little bit healthier I'm getting some protein in my kids are getting protein so they're not starving at school right so and it's whole grain like if you read the ingredients on here and this isn't sponsored it's just not true it's my favorite like the ingredient list you can pronounce everything that's on there which is a huge plus to me yes so we're just going to do one cup of kodiak cake and then three fourths cup of water so we're just following literally the instructions that are on sometimes I will add a little bit of cinnamon and vanilla to it as well just to kind of give it a better flavor it's good it really is good it's just a buttermilk flavor but cinnamon and vanilla they make everything taste better I agree okay so you mix that I'm gonna spray this with cooking spray just because it makes my life a little bit easier if it's sprayed it comes out really nicely okay cool all right so so with this I just do about like two scoops full of the batter because you don't want it too full because it comes out the edges so spread it around a little bit sound like you're speaking from experience oh and my kids too oh no you did the waffles by yourself too much but anyways just wait for this little light to go off and it's okay that's the cutest little waffle maker thank you I love it I love it you can use a big waffle maker too definitely use big waffle makers and then freeze all the waffles and then do you just cut them into fours or what to do okay before us like we have some that are like squares so there's four squares but like you said they don't fit quite into the toaster as easily so I do like me even though it might take a little bit longer but this is another one too if you've got big kids like let them they can do it though let's make waffles one day and then stick them on the freezer I love it okay so when it's all done we're just going to open it up that is the cutest little waffle isn't it so cute yep so cute perfect and then you go again yep until your badness is done okay so once you've cooked a few um I just like to stick them in a freezer bag yep perfect you want to make sure they're all the way cooled down yes you don't want to put them in hot no and I just I stick them on top of each other and you too and you can use smaller freezer bags if you want to but I usually fill it all the way up on all your side yep if like and I don't know a dozen of those okay and then I usually just pull one out or two at a time whatever I need and stick in the toaster or even stick in the microwave is fine yeah I've done that too well I hope you guys loved these freezer meals now if you want more freezer meal ideas we have a lot of instant pot and slow cooker freezer meals we just thought it would be fun to do breakfast freezer meals today so if you want to check out those videos there is a video link down below just for you and if you are new to this channel don't forget to subscribe and give us a big thumbs up and we will see you guys next week see you later bye


In fact, IoT uninformed users and the incorrect usage of null references are the hacker's dream trifecta because IoT, these little smart gizmos and gadgets that people like so much, especially people that don't have a lot of infosec knowledge to begin with, those devices are often times running software that is so buggy and insecure that a kid taking his first Java class in high school probably could have done a better job at writing it. So combine that with the fact that these devices are often hard to update and they often require a constant connection to your network and of course the average person that's buying these devices, they don't know how to secure their network, they don't know how to create any firewall rules to restrict what kind of communications these devices can make, and you've got a $20 smart piece of junk that doubles as a backdoor into your home network for any script kitty that's running Kali Linux to exploit. Rooting your IoT device will likely be a piece of cake, there's probably literally guides on the internet for how to do it and he'll be able to add that device and possibly even your whole network to his botnet that he rents out to other hackers for all kinds of nefarious activities. Now luckily for those of us that are living in the real world right now, this news report about three million smart toothbrushes being used in a massive DDoS attack that disrupted the operations of some Swiss company is not true or at the very least there was some kind of information that got lost in the translation from the original article and you know there's a lot of core details from the original articles that were missing like what company was attacked by the DDoS, what kind of smart toothbrushes were used in the attack, what hacker was claiming responsibility and so on. And I'm also a little bit skeptical about this from the very beginning because that many smart toothbrushes being used in a DDoS attack just sounds like too many right like three million devices for one would actually make this one of the bigger botnets to date. So yeah when I first heard about the supposed toothbrush botnet I was really skeptical about it but it also got me thinking about smart toothbrushes today right. How could they be used for some kind of nefarious activity because my first encounter with smart toothbrushes was while I was working at Best Buy. So my store had a couple of the I think it was a Philips Sonicare toothbrush that had Bluetooth functionality right like a pair to an app on your phone that was supposed to show if you're brushing too hard or too soft or for not long enough or whatever and log how often you brush your teeth and all this data is supposed to help you have better oral health or maybe you show it to your dentist and they interpret it for you if you can't read or understand the results.  Now I'm not saying our store never ever sold one okay like obviously somebody's buying this stuff if Best Buy is putting it on their shelves but I had a few customers ask me about that toothbrush over the years that I worked there and the general consensus from just my small sample of Best Buy customers was I would never pay $300 for a smart toothbrush but then I started searching online today for smart toothbrushes right this is this is probably I don't know six or seven years since I've even thought about a smart toothbrush and what do you know the Bluetooth gimmick has been copied and it's made its way into toothbrushes that cost less than $30. Philips even makes a Bluetooth enabled toothbrush for kids electric toothbrushes they may soon go the same route that flat screen TVs went where these days it's not even possible to get a flat screen without so-called smart capabilities right without some kind of usually Android OS built into it right if you just want essentially a monitor right like a display panel flat screen it's not really possible to get that at least not in stores like Walmart and Best Buy. Now some of you are probably wondering still how a Bluetooth enabled smart toothbrush could be used for a DDoS attack because usually these are running some type of Bluetooth low energy right BLE and a BLE toothbrush shouldn't be able to connect to the internet but it depends on how you define connect to the internet so all of the BLE toothbrushes connect to some type of app that's the whole point of the Bluetooth gimmick and if the app has internet access which probably does if it's on your phone then in a way the toothbrush is connected to the internet with the app on your phone acting as a two way proxy that pushes firmware updates and maybe some other data to your toothbrush and then data about you brushing from the toothbrush to the app and then possibly out to some cloud for you know most likely some company to sell to other companies now here's where things get really interesting with this theoretical idea of a toothbrush botnet if a hacker is able to take over the app that is sending communications to and from the toothbrush either through a supply chain attack or tricking a user into just installing a malicious brushing app that's masquerading as the real one then the hacker could push a malicious firmware update to the toothbrush which might be able to enable direct internet connectivity from the toothbrush depending on what kind of chip is handling the BLE connectivity because you see a lot of devices they actually have their Wi-Fi their Bluetooth and like pretty much all their wireless functionality built into a single chip these days and this consolidation of different computer parts into a single chip is a really popular technology trend that's honestly been going on since the beginning and it's a big reason why computers keep getting smaller and smaller yet faster at the same time plus some smart toothbrushes like the oral be since they actually do have the ability to connect to Wi-Fi directly via the smart charger which just like any other smart device any other IOT device it's likely not going to be updated or it might just be running poorly coded vulnerable software from the very beginning and so my predictions about smart toothbrushes going the same route as smart TVs is correct and they become as common as regular electric toothbrushes and they end up having these BLE plus Wi-Fi chips installed in them or their smart charging bases then I think a story like this could not only become real but it could become a very common occurrence where common household items are made dumb by smart features and then hacked so don't be that person that contributes to device sprawl by buying a BLE toothbrush for yourself or loved one I really don't buy into this gimmick that these apps really help you clean your teeth better like one of the more common things I've heard that they help with is to just help you stop brushing so hard but I think a better solution to that is to just brush your damn teeth correctly like seriously how have you not perfected something that you've been doing every single day yourself since the age of three and look I'm no dental expert I don't know how many people are brushing their teeth too hard but I really doubt the proliferation of smart toothbrushes is going to have any noticeable positive impact on humanity's oral hygiene this is just another non solution to a non problem to trick you into spending money on something you don't need if you want to have better oral health then just brush your damn teeth and eat less sweets and maybe less like stuff that's going to be corrosive to your enamel if you want to keep track of your kids brushing their teeth just touch the damn toothbrush to see if it's wet or see if they have bad breath because bad breath is literally nature's built-in indication for people to tell if you're brushing your teeth correctly you don't need an app for that the devs included it in the vanilla build like and comment to heck the algorithm buy my merch on base.win to help support the channel and have a great day


Hi, my name is Andrea with Food and Mentory Adventures in Food and today I'm sharing four quick and easy dinners using one of my favorite pantry staples, rice errone. I'll make sure to leave the recipes in the description box and if you like this video, please make sure to hit like and subscribe. Today, I'm making zesty Spanish beef and rice. So I have one pound of lean ground beef in my skillet. To that I am adding in some onion and bell pepper. I am using frozen just because that's what I have on hand and that's just more convenient for me. So I'm just tossing that in there and then I am going to season the mixture with some garlic salt. This is the brand that I really love, Laurice. And I am just going to let this cook completely. So my meat and veggies are done and I just poured in two cups of water and I am pouring in a can of diced tomatoes undrained. Butter and now I'm going to stir in the contents of the rice errone box. So I'm using Spanish rice and the little seasoning packet as well. And I'm just going to give this a good stir. So I am just going to let this come to a boil and as soon as it does, I'm just going to cover, reduce heat, let this simmer for about 20 minutes or until that rice is ready. Okay, so here is everything all plated up, super quick and easy. And I am serving this with some fresh buttered and salted corn. Today I'm making green chili chicken rice errone casserole. And I am starting off by preparing a box of chicken rice errone according to package directions. I am using the low sodium variety and I have just sauteed my rice mixture in a little bit of butter and now I'm adding in my water and my seasoning package. And then I'm just going to let this cook up. Okay, so my rice errone is fully cooked. Now I'm adding in my cooked chicken and I've got my oven preheating to 350 degrees. Adding in some diced green chilies. Now if you are sensitive to heat or if you're cooking for kiddos, you don't have to add these in, but I'm adding them in and I'm adding in some sour cream, can of cream of chicken soup and some Monterey Jack cheese. I'm sorry pepper jack cheese. Now again, if you are sensitive to heat or if you're cooking for small kids, you can use just regular Monterey Jack cheese instead of the pepper jack. So I'm putting half of it in, I'm going to stir it up and then I'm going to put the other half on top of the casserole. So my casserole is ready to go into the oven. I am using a greased 11 by 7 pan. The recipe calls for you to use a 9 by 13, but I always use the size pan and I don't have a problem with it at all. So I am just going to pop this in the oven and bake it for about 30, 35 minutes. Okay, so here is the casserole. As you can see, it was so easy to make. Here is our plate. I am just serving our dinner tonight with a side salad. So for dinner tonight, I am making rice errone ground beef stroganoff. So in my skillet, I have prepared a box of beef rice errone according to package directions. It's not cooked all the way through. And at this point in the recipe, you're supposed to add in fresh mushrooms. But as you can see, I have sauteed my mushrooms. I just didn't want to put them in there raw.  So I did saute these in butter and I added some garlic salt as well. Of course, that's totally optional. You can just put your raw mushrooms in there. And then it also says at this point, you're supposed to add raw onion and raw green pepper. But I sauteed my onion and ground pepper, I'm sorry, my onion and green pepper with ground beef, as you can see here. And so now I'm just adding that into the rice mixture as well. So I'm going to stir this up, cover it and let that rice continue to cook. Okay, it's been about five minutes and my rice is completely cooked through. Now all I'm doing is stirring in some sour cream.  Just going to stir this in really well. Okay, so here's our dinner, another quick and easy recipe. And we are having side salads with it. So for dinner tonight, I am making Jambalaya, making a couple of modifications to the recipe. One of them is that I'm going to be using chicken rice errone instead of Spanish rice rice errone. So I've got some butter melted in my skillet. And I'm just pouring that in. And it also says the directions also say to add in my bell pepper and my onion at the same time. So I'm just putting that in. And it says to add in some garlic. And I'm just going to give this a stir. And it says to let this get nice and golden brown and then to add in my smoked sausage. But I do want my sausage to have a little bit of color to it. So I'm going to add in my smoked sausage now with everything else so that that can get a little bit brown. So I am just using this smoked sausage that I picked up from Aldi. And I've already cut it up. And I'm just going to put it in the skillet and let it get everything get nice and brown. Alright, so everything is nice and brown. I'm adding in my water, a can of diced tomatoes drained and the contents of the seasoning packet. And I'm just going to give this a good stir, cover, reduce heat and let this simmer for about 20 minutes or until that rice is cooked through. Okay, so here is dinner, another quick and easy meal. And I am serving it with green beans. So I hope you all enjoyed all of the quick and easy rice errone meals this week. If you did, please make sure to give us a thumbs up. And if you have not subscribed to our channel, we certainly love to have you. Thanks so much for watching and we'll see you all next time.