Hi you guys! Lindsay here. Welcome back to my channel, Inside the Hymn. Well, just as promised, Simplicity's new winter holiday pattern collection dropped earlier this week and so it is in the queue for today's first impression Friday. I love when things work out in such an organized fashion. Okay, so I'm just going to jump right in because as we know these videos can be a little bit long, but we're starting out with Simplicity 9010 Mrs. Dress with length variation. All right, so it looks like we've got a elasticized waist, some kind of like baggy situation, long skirt. Let's see what other kind of photos we can get. Great color, that emerald green I'm telling you all about and let us not forget that Simplicity still has a very difficult website to manage so bear with me even though it's a little bit clunky in the beginning. Okay, so cool. So we've got this surplus or wrap back which is really beautiful. This looks like a full grown-on sleeve to me. So for those of you that participated in the so-along that I just did, this is pretty much the same thing just worn backwards. So that makes me want to go in my closet and try on that dress backwards. It does have this really beautiful back slit here. The length is notable, the slim skirt. Other than that, yeah, it's a pretty straightforward and simple pattern. Let's see, oh, here's a shorter sleeve which is a nice option and a shorter length. So it looks like they're giving us the reviews which I'm assuming A has like a closed up back. We'll get the line drawings here in a second and then B is what she's wearing and then C has the shorter length and the shorter sleeves. I also want to know what this is for knits just like the so-along was and it can be. Okay, so it's designed for woven fabrics, crepe, crepe to sheen, double georgette, but you can do it in more stable knits like Ponty doesn't have hardly any stretch to it. Even Stretch Velvet has just very little stretch to it. So I guess, all right, fine. It's a woven version of the so-along dress that we just did, but honestly that so-along dress is so roomy. You could do that out of a woven as well, you'd be just fine. All right, so thread, bias tape, I guess for the neckline and then elastic for the waist and then you need a button for view A to close it up in the back and you can see that A is a closed back, B has an open back and C might have like a little tie. I can't really tell that illustration is so small. Here are your fabric requirements and then finish garment measurements for the bust and for the hip, which is really nice. Thank you for doing that, especially because this is a slim skirt and it does look like even though it's slim, this elasticized waist is allowing it to be very forgiving in the hip area because I fit into the middle of the size range where normally in like pencil skirts, I'm like all the way over here somewhere. Okay, so yeah, there's a little tie keeping that closed, which is nice for view C. Lots of great options here and trust me, I can tell you from experience with the so-along dress, this style of dress is very comfortable. Like I want to wear mine every day, but people are starting to question. Okay, so off to it. Pretty good start. It is sort of basic, but I like all the options, which is nice. Okay, so now we've got another grown on sleeve. This has got to be knit. There are like zero seams. I don't even know if there are side seams to be honest with you. No seams. This has got to be a knit dress. Okay, great. Length variations, sleeve variations. Here's another sleeve. Yeah, that's a sweater knit for sure. That's cute in a sweater knit. Uh, easy to sew. Yeah, I'd say so. Still can't tell what's going on. Let's go to the line drawings. Okay, so there is a center back seam and I'm assuming side seams. Yeah, so that you can sew up the sleeve. So, wow. Okay, so three pattern pieces. That's amazing. It looks like you're going to get, wow, this has got to have a ton of pattern tissue. Well, you'd get this and this would all be one and then you'd have like cut here for review A and cut here for review B. And then I'm assuming that this and this are the same. And then D just has the cuff and C has the elastic. That's what I'm guessing. That's still, that's a lot. Knit pullover dress in two lengths with sleeve variations. Size for stretch knits only. Bamboo, jersey, ITY, modal, knit, rib knit. Yeah, very good. Okay, and then fabric requirements. Here's your finished garment measurements for the bust and for the hip. See how this one's a little bit more close fitting. And I think that's because it's designed for knits. So they want it to be kind of hugging the body a little bit. Yeah, not my style, but man, it's going to be a breeze to sew, especially if you have a serger. Pull on slim dresses in two lengths with grown on slaves, choose between a straight gathered or cuff sleeve. Easy to sew can be constructed using a serger. Yeah. Yeah, you just zip that on through and I'm pretty sure that the neckline is just a fold over situation because I don't remember seeing any notions, thread, and some elastic for that one sleeve. So yeah, super simple. Great. And that was 9011. Ooh. Okay, so this reminds me of a Cynthia Rowley dress that came out, gosh, maybe two or three years ago. And again, with that trappy silhouette that I commented on with the Vogue first impression winter holiday collection, this one actually has a neckline that I am obsessing over and ready to wear right now. And it's still utilizing the statement sleeve trend. It comes in letter, alphanumeric sizing. So that's interesting. 9012 Mrs. Dress or top and belt. All right, let's go to the bigger pictures. Let's make this a little bit brighter. That'll help see some of the details. Maybe a raglan sleeve. I'm again, loving this little gathered neckline. Here it is with the belts. I don't know. I kind of like the the wide but short silhouette. I think if you're going to belt it, I would want it to be a little bit longer. And then this sleeve trend is also so fun. I love that. Here it is in a drawing. Yeah, raglan sleeves. That's fun. Here it is as a top. Oh, and it's another Cynthia Rowley. That's so interesting to me. Who remembers that dress from a couple of years ago? I feel like it was like baby blue and had like white bow in the back or something. Anyways, this is very similar to that. But I actually like this one. I never bought that other Cynthia Rowley one. But this one I adore. I just adore this. Cotton lawn, lightweight satin, silky types. Silky types are going to fall much closer to the body. Soft cotton types, soft linen. All of those other fabrics, the cottons, the satin, the linen are going to have a little bit more structure. So they're going to pull away from the body like the sample does. All right, there's your fabric requirements. You need a lot for this much width. And because there's no other seam, it is it will take up a lot of fabric. And then you just have your finished bus measurements, which honestly, that's all that really matters. You could probably even sew a straight size if you normally have to grade. I wouldn't worry too much about grading. I mean, double check of course, but finished bust measurements. Oh, wow, it jumps by four inches each time. Yeah, honestly, colleague, honestly, I don't know how you'd figure out what size to make because it's so roomy in the bust as well. I guess you just go off of the envelope. That's risky. Yeah, I mean, technically, I could make an extra small based on the bust measurement, but I'm never going to do that. Yeah, here are the sizes. 10, 12, 14, 16. So according to the body measurement chart, I'm more of a medium, which makes sense. So yeah, I would just go off of this and then when you get your pattern pieces, check the finished waist and the finished hip, which should be printed on the pattern pieces and just make sure that it's not super extreme. But yeah, there are, if you look at this, like let's just assume you have a 36 inch bust. That's an 11, that's 11 inches of ease in the bust. That has a lot. Did she have that much? I don't know. It's really hard to tell. And now that I'm looking at it, I'm not really in love with all of this. Oh man. I'm worried that this is cute, but people are going to have a lot of fit issues with the ragland sleeve and then all of the gathering situation and the fullness situation. I don't know if she has 11 inches through here. I'm thinking more like six. Let me know in the comments what you guys think. Does this seem right, this fitting chart? 11 inches of ease? That's a lot. Right? Is that a lot? Let's find out. We'll crowd source the comment section. Cynthia Rowley, loose fitting mini dress or top with optional bell, neckline gathered to ruffle, stand up collar, ragland sleeves with tiered frills, lightweight loaves. Okay. Here's another similar design. I think this one's also going to have the ragland sleeves possibly and gathered situation of the neckline, gathered situation of the waistline, maybe a separate band, long sleeves. Yeah, this whole, I don't know, sort of Victorian, sort of nightgown silhouette is definitely having a moment here. Here's the back. Beautiful fit on her. Maxi dress length. There is the line drawing where you can see the neckline gathers. There's also a little slit here, some waistline gathers. And I feel like this is a little bit above the natural waist and possibly curved, which is also nice. I think that adds a beautiful fit. Very slimming. Here it is in a shorter length with a shorter sleeve. Another Cynthia Rowley.  Here is the envelope back, cotton lawn, double georgia, silky type, soft weight, linen types. Here's your notions. Here's your fabric requirement. I guess the bodice is lined. That's a nice and then your finished bust measurement. So for comparison, this bust that's 36 inches only has, what is that? Well, this one says this one has seven and a half inches. So compared to a 11, you know, again, though, it doesn't look super full to me, but maybe it is. Yeah, I would love you guys's thoughts on bust ease. I always thought that for like a fitted, like a fitting flair, it was like two and a half inches. So for something that's loose fitting, but not incredibly loose fitting, seven and a half, 11 inches seems like a lot to me. Let me know what you guys think in the comments. Okay. Cynthia Rowley Empire line dresses in mini or maxi links. Bodice is gathered into narrow neckline with front slit. Sleeves have elastic coughs suitable for lightweight woven fabrics. Yeah, it's a really pretty dress. I can see a lot of really beautiful versions. Oh, it's also not a rag one. Like I had said before, it's a set in sleeve. So I feel like I have dresses like this. This isn't really, you know, that new and different to me. But great transitional dress, that one, you could make it for spring, you could make it for fall, winter. All right, here is simplicity 9014 knit tops with variations. Okay, they find the youngest models don't they? All right, so this looks to have some kind of like cowl drop shoulder with a sleeve that's very long, loose, long dress. You know, they're styling with tights and boots here. I don't particularly love a sweater dress. I mean, look at this callee. That can't be how it was intended. Yeah, no slouchy funky back on any of these. I don't know what that's about. I guess her neckline was falling. Maybe this knit is too heavy. That's one of the reasons why it's really hard as a home sew is to like, sort this all out. This is supposed to look like this. Right? That's that's not translating. The neckline is too big. I don't know. This whole like slouchy drapey, I don't know. I'm sure it's comfortable, but it certainly doesn't look like the drawing. This is a different version. I can't really tell how it's different. Here's another one, I guess that's just contrast fabric. And then here's one that's short with no sleeves. Oh, A is longer than B. Okay. Yeah, this neckline, something's not right with that. Size for stretch knit only, interlock jersey, ponty, stretch velvet, sweater knits, tearing it. Okay. Yeah, so this one has, I keep going back to this bust thing. It's just really on my mind. This one has 12 inches of ease. And I mean, that looks a lot roomier than that baby doll dress, right? Okay. You don't need a ton of fabric. Well, I mean, he had two yards for a dress. That makes sense. I don't know if you had like, I don't know, the right perfect kind of fabric. I don't even know what to suggest. I was, I would suggest a rib knit, but this just looks not great. And I don't know what's up with that neckline. It just looks sloppy to me. This one does. I'm sure this is all one piece. So you'd have to kind of fuss with it a little bit, but then because it's a knit, it's wanting to pull down and stretch out. I just feel like concept to execution, something went awry. What happens? Lots of sizes. Double XS to double XL. Loose fitting tunic or tops with cowl necklines, drop shoulders, loose sleeves. Easy to sew. Okay. All right. Now we've got a little coat. Simplicity 9015. Okay. Looks like a shawl collar with one little toggle. Maybe some buttons through here, a belt, pretty long with a slit. Here's the back. I would prefer if this would have become a hood if you could have zipped it. I like those styles. This just looks, what's that show about the midwives, call the midwife, something like that? That reminds me of whatever time period that is. There it is in a shorter length. I just don't know what purpose this provides. Like it doesn't pull up to keep you warmer. Maybe the double layer around your shoulder keeps you warmer. There's no, other than design and it looking different what the point is. And if people honest, I don't love the way this looks in the back. It's cool in the front. But, and then here's one with a contrast inside. So you could do shirling or fur or something like that in there. Which that's cool. I also like it unbelted, like they're showing here. Yeah. So yeah, just a couple different lengths. That's really it. So it's really just one pattern. Side seam pockets. All right. Boiled wall, denim, corduroy, linen types, ponte wool types. Oh, it's a double faced fabric. Such a suede backed sherpa. I didn't even know that existed. Well, I guess leather and suede. They also have some, I want to say it's some kind of wool, but it's like a two tone, almost like a, like a double knit or like a double gauze. It's like a doubled wool where it's like navy on one side and then like, I don't know, some other crazy like orange, the complete opposite on the other side. I remember seeing some, I was in a mood. I can't remember. But yeah, that's a really fun idea. Okay. So one coat snap, one button, a lot of double fold bias tape. I'm assuming that's because it's not lined and they're going to instruct you on how to do Hong Kong seams on the inside. Also kind of cool that it was designed that way. So, but then does that mean that this is just the wrong side of the fabric? No, it looks like there's a, it's stitched. There's a little facing there. I don't know. And then finished bust measurements. This one has nine and a half for reference. Yeah, I don't know. I'd be interested to go to the store and read through the instruction booklet on this just to see how it's constructed. It does seem fairly straightforward, fairly simple for a coat, which are all great qualities. And like I said, I do like this version a lot, especially if you found that really cool fabric, you'd be able to make something that people would be like, I can't believe you made that online wrap coat or jacket and two links all with oversized collar single button or toggle fastening easy to sew. Yeah. That's cool. All right. Next up, we've got some asymmetrical skirt simplicity nine, zero, one, six. Oh, that's fun. So some interesting gathering and this like little overlay sashie thing. Asymmetrical hem. Here it is in the back. Looks like it has, I don't know if that's a facing or itty bitty waistband or what. It does have an element of like circle skirt ishness to it. And I think that they were trying to pull off like, wear this to a holiday event, you know, like this is like a dress up skirt or dress down. Do you know what I mean? Like this tone on tone. But this is reading more like ballerina, you know, leotard and little chiffon skirt, maybe in a different color. I'm thinking if it were black, would that matter or if the top were like sequins or something? The front is super interesting, though. I'm guessing these are all different lengths. Oh, that's cute with a little belt.  So it looks like a little dart here that the stuff is sewn into and then kind of a princess seam here. What's this one saying? I don't know guys. Am I here for maxi skirts? Let's look at the one drawings. And then the back has the one dart and then another princess seam here, side zipper. And I'm assuming this thing goes into the side seam since I'm not seeing it on the back anywhere. I don't know. It's kind of cool. It's kind of like dressy hippie. I'm picturing like when the hippies transformed from like tie dye and like calf dance in the 60s, like what are the hippies? Like the hippies in the 80s, like Goldie Hawn in some of those 80s movies, right? Or like the mom character in the 80s movies. That's what this is giving me. That's what this is reminding me of. Okay, crepe, double georgette, silky type, soft cotton types, lightweight linen, lightweight denim, zipper, twill tape, and a D-ring. Are they trying to tell me that this is twill tape? This little belt is made from twill tape? I don't know. You could use leather strapping. You could use something way cooler than twill tape. All right. Here's your fabric requirements and then your hip finish garment measurements. I wish they would have included the waist here since it is sitting at the waist. I don't know. I think I want to like this. We'll have to see how much I think about it after I'm done looking at everything. A lot of times too, at the end of the video, I'll just try and make note of the ones that I remember, like the ones that stuck out in my mind, and those are the ones that I'll usually add to my list. All right. Very good. Sizing comes in 6 to 14 and then 16 to 24. All right. Here's a cool little top. This is Implicity 9017. This is knit tops, pants, and skirt. So a lot of bang for the buck. I love this top. This is fun. There's also some seam here.  The pants, hard to tell, but cropped, sort of loose fitting. And then styled with bronze duck martins. And then the back has the asymmetrical seam. So interesting. That's cool. Here it is, color blocked. That's also fun, so you can get an idea what the pattern pieces look like. This is like grown on. It's all cut in one piece. Here are the pants. They do have a waistband. Doesn't seem to be elasticized. Maybe the back is. So we're getting away from that, but this is like the perfect ponty pant pattern. And then a little skirt. Give it a let me. Skirt. There we go. Simple, simple skirt. Here are the line drawings for the pants. Yeah, nothing's elasticized and they're pull on. Oh, these are going to be good ponty pants. I had a pair of ponty pants. I've had a couple actually. And they're very comfortable, but they look dressy and they always, like they never pill. They always look pressed. They never wrinkle. They're warmish. Ponty pants are good. All right. So size for stretch knits only. Jersey, ponty, rib knit, stretch velvet. A and B is also in sweater knits. Thread, elastic. Oh, so there is elastic in the waistband, one and a half inch wide, but it's not like pulling the waistband in. It's just kind of, I think, pretty much holding it up and giving you room to pull it on. All right. Here's your fabric. And then they give you bust and hip measurements. Finish garment measurements, I mean. Very good. The sizing is numbers, six to 14 and then 16 to 24. Coordinating top pants and short skirt. Pull on top has grown on sleeves and slanted neckline. Pants and skirt are pull on with elastic waist. All designed for stretch. Yeah. This is a good one. I want to make those pants. I want to make that top. And why not? I'll make the skirt too. Just looks very comfortable, but cool and chic still. Okay. Here is simplicity 9018 Mrs. Pants knit vest, dress or top. So I'm assuming she's wearing the dress, which has a little mock turtleneck. Then this thing is the top, maybe the vest overlay. That's interesting. It's weird to me that they use such young models, but the designs are a little bit older. Like that's a mature outfit. You know what I mean? There's the back view. Here's the dress. Very simple, straightforward, set in sleeve, no seams, sort of figure skimming with a slit. Here's the top, which is undoubtedly a great basic to have in your wardrobe little mock turtleneck top. Here's the vest. I don't hate the concept. I just don't know if it's executed very well. Maybe the length of it is what's throwing me off. Maybe the fact that I know that this little doom-a-hick here is incredibly difficult to sew. Maybe that's why I'm like, no. And then our favorite elasticized pant. I just don't know. I just don't know. And I wish that they gave us a picture of her in the dress without the thing so we could get a good look at this. Like what this looks like on the body. Obviously you can also shorten this too. I just don't know if this is giving me enough to jump on buying the pattern. Oh, look at that. That's the, that's how the vest is cut. Yeah, I don't know. I want to like it. I do. But it's not the fabric choice of the samples. I know they did a fine job on that. I think maybe it's just the length. But I can't, I can't convince myself that a shorter length would look a lot better either. So that's why I'm so torn. Maybe if people start making it, I can look at those and decide then. All right. So A, B, and C, the dress, the top, and the best are designed for jersey, velvet, sweater knits. D, the pants are for cotton types, jersey, linen types, silky types, stretch, velvet, sweater knits. Sweater knit pants. Okay. Okay. If you say so. Alpha numeric sizing and finished bust and hip measurements. I also find it a little hard to believe of D's hip, not A. Okay. I was like, I don't see how D and A will have the same finished hip measurement. So I mean, if you're interested in making the pants, this is helpful. But what if you want to make the dress? You know? All right. Any other info down here? Pull on slim fitting pink dress and top. The neck best is pull on and loose fitting pants have elasticized waist. Easy to sew, blah, blah, okay. Next, we have Mrs. and Girls Loungewear. We can take a look at this since they're, they do include Mrs. Ooh, there's gonna be lots of, lots of family fun pajamas this year. This is Simplicity 9019 and the, looks like there's just one size. It looks like a little fleece situation. That's hot. You've got your pants with like a little, maybe a drawstring? I don't know, hard to tell. This little mock turtleneck situation, a little, maybe something happening here. I see a kangaroo pocket. Her little glitter inset heart is really cute. There's the back. I can't tell what's going on there. It looks like a safety pin, be honest. Mom doesn't have it. The backs don't have it. Weird. You think they safety pinned that? And then forgot.  That's cute. I want to make the one with a heart, honestly. Elasticized pants. There's other ones. And then there they are. Fleece, minky fleece, sweatshirt fleece, tearing it. Yep. B, applique and sequin. C, which is the pants. Can be made in cotton types, flannel, or obviously any of this stuff. You have your girl sizes and your missus sizes, finished garment measurements for the bust and the hip. And you really don't need a ton of fabric. So that's good. Cute. Pull on loungewear pants featuring elastic waist, loose fitting tops, have funnel neckline. That's what that's called. Front kangaroo pocket or heart applique. I want the heart. All right. Here's another pajama situation. Simplicity, 90-20, missus sleepwear, knit tops, pants, shorts and accessories. This is fun. So we've got a kind of wide neck, drop shoulder, tunic length, sweater top thing and pants. Here's the back. The pants have a little cuff on the bottom. Here's that top. Here it is short sleeve. Here are the pants. Come on pants. They have side seam pockets and a little patch pockets like a lot of pockets for pajamas. I don't know what you need to be carrying with you to bed, but to each his own. And then here's a little cuff. Here are the shorts. And then you get an eye mask and look at this illustration, a scrunchie. That's funny. Yeah. See, there's this crunchy. That's fun. How fun. Okay. So jersey, interlock, stretch velvet. Wow. Fancy pajamas. A twill tape. Oh, these are all for like the drawstring elastic also for the pants and shorts. What do they give? Oh, they do get finished tip measurements. All right. Not bad. Yep. Yep. Yep. Yeah. They give you everything that this looks pretty good. I like this pattern. This is cute. If I found the right cozy cotton jersey, I think that I would definitely make this for myself. I haven't made pajamas since my Carolyn pajamas. I can even tell you how long ago that was. Look how easy peasy the top is. And I mean, not for nothing, but you could wear that top out. You know, I'd probably make shorts and the long sleeve version though for the weather here. It's cute though. All the sizes come in one. So if you wanted to make it as gifts, you could make, you just trace off the pattern and make it for everybody in your family. Yep. Okay. Cool. That's fun. Thoughtful with the accessories. And then here's the family robe. We'll go through this one quickly. Isn't that the cutest little family? So yeah. One robe. Four sizes. Raglan sleeves. This looks like a really lush robe. All right. Here are the line drawings. So I'm assuming this is, you know, adult and children. Yeah. It's just got a, you know, notched collar, raglan sleeves, cuffs, a belt with belt carriers, patch pockets. It's a robe. And there's the back. This is actually a really nice robe pattern. It has, it's very traditional. Has everything you need. Nothing you don't. So that would be fun. And it looks like everything comes in one size too. That's also nice. Cozy, reversible. That's a fun detail. Wrap robes, feature raglan sleeves, turnback cuffs, belt carriers, and a tie belt. Suitable for flannel, fleece, interlock, terry, or velour. Oh my gosh. Another robe. Okay. Harry Potter robes. I, okay. I never got into Harry Potter. I never read the books. I never watched the movies. Please don't hate me. So I cannot speak to anything that's happening here. I don't know what the colors mean. I don't know what the little Duma Hick means. I don't know any of that. So I'm sorry. But I'll just, these robes do have a hood. That's what makes them different than the last ones. They also have these really funny sleeves, which I'm assuming is like wizardry type sleeve. And I'm also guessing that they are not reversible. So, all right. Fun for the whole family though. And then these are all little kids patterns, which I don't make. Oh, look at these like tween patterns. Also bags. Wow. Look, headbands. Let's go through these accessories. Oh, this website. Um, yeah. So it's like a little fold over, either shoulder bag or a tote. That's interesting. Oh, they're all the same. You know, let's look at this. This is kind of cool. I like this. How the little thing is removable. And then you just have like a, you can hook it here for a tote bag, hook it here for a cross body or just carry with a handle. And then I wonder if these are provided or not provided. But yeah, you buy the flower applique separately. That's interesting. And then also the handles, yeah. It's a little complicated to get all the notions together for bags, but it's still fun. The tassel thing here is kind of cool too. All of them are zip top. Interesting. Okay. And then you've got this headband. I wonder if this will be added to the Cricut library since Simplicity and Cricut have a co-branded situation happening. This is one of those that just, it's just like a one long strip and then buttons or velcros or magnet closure or something is happening here.  And then this other kind of hat. I don't know much about hats, but there they are. What do the hat notions look like? Just really interfacing. Where, which one? The headband? Oh, maybe it's sewn shut. That's got to be really easy. Great gift, especially if you have an embroidery machine. Yeah, oh no, purchase flower applique. That'd be fun. And then these scarves is like the Chewbacca. Chewbacca with a silk bow. That looks like fun. Okay. Yeah, it's kind of hard to tell what's happening here, what the patterns actually look like, but this, why is that? I was about to say this will help, but not really. I don't know. They're kind of cool. I like this one a lot. Maybe not in that fabric, but certainly a good scrap buster, right? And what do we have here? Three eighths, five eighths, three quarters. What's an upper middle and lower? I don't understand that. This one takes three eighths. Yeah, about half a yard for all of them. That's fun. You don't see a lot of other pattern companies doing accessories like that.  We're really getting away from clothes here guys, but I don't know, this crafting stuff is tickling my fancy at the moment. This includes stockings, an advent calendar, and then, is that supposed to be a paw print?  Christmas tree countdown calendar with pockets for treats, dog or cat Christmas applique stockings, and a gift that says for pets. That's hysterical. Okay, an advent calendar for Sunny. What do you guys think? I know what you're, you're already getting to the comments section as we speak. All right, and that's it. This is taking us to the bird of style fall that we've already done. So, yeah, that was kind of short and sweet. I don't know, what did you guys think? They're calling it the winter holiday, but I'm not getting a ton of holiday vibes. Mostly winter vibes, mostly pretty basic stuff here. I do like this one a lot, and I do want to figure out what's going on with this one. And then the shorter jacket version of this was okay, and the pajamas. That's really all that's standing out to me here at the end. But let me know what you guys think. I'm kind of surprised there's only three, six, nine, nine non pajama sleepwear patterns. That's kind of surprising. It seems like not that much, right? Yep. Well, anyways, that's going to do it for the simplicity first impression video on their winter holiday collection. Let me know your thoughts in the comment section below. And if you're not subscribed, please do so. I will have another video just like this one coming out. But yeah, that's going to do it for me today. Thank you all so much for watching. I will see you next time. Bye.


Welcome to the class on molecular biophysics. I'm Erik Lindahl and I'm going to be your teacher for the next 12 or 13 lectures. Great to have you here, even though it's only virtually. What I'm going to do with the class is that although there are 13 so-called lectures, each of these lectures is going to be split in between 10 and 20 small concepts where I try to divide things up so that you can rehash a concept until you feel you understand it. If you want the traditional lecture, just view the entire playlist and then go back and repeat each concept until you feel that you master it. Today is a bit special, though, since it's the first lecture and that means that I'm going to start with a slightly longer introductory concept to give you a bit of an overview of what we're going to be looking at in this class and the type of problems we're interested in, both in biophysics in general and in molecular biophysics in particular. So, join me. The first things I'm going to tell you is that biophysics is everywhere around us. I'm sure you've all seen things like an insect being able to walk on water. There's an amazing amount of biology and evolution in this problem, but at the heart of it, this is a physical concept that the surface tension of the water, i.e. the special properties of water, makes it possible to do something biologically, in this case for a very lightweight insect to walk on it. You can have another challenge. Imagine something highly complicated compared to an insect, such as a bird flying over billions of years of evolution. Birds have evolved into being able to flap their wings at the very right point in time to maximize the amount of lift they get relative to the energy they're putting into this. Of course, the bird doesn't know how to do this. It's just mechanically, it does it the right way. Well, I'm not a bird, so I don't know how. But one way or another, they do manage to do it without having taken an advanced degree in physics. Of course, we can calculate this, but biology has somewhat managed to do this through billions of years of evolution. And in the muscles of this bird, we essentially have proteins. And in the brain, you have nerve cells controlling this. We're not going to be looking that much on birds in the particular class, but the concepts will keep coming back and looking at problems. Something else that we're not going to be looking at the class is, say, fish swimming in a school. There is a lot of information you can learn from fish. Sabra fish is used in almost all facilities for molecular life sciences to express proteins. But what about the particular problem of understanding why fish swim in a school? That is, many of them swim together. Well, colleagues of mine who are actually computer scientists and mechanical engineers in Switzerland, they have studied that. And by using supercomputers and fluid dynamics, we can use physics, fluid dynamics to understand that when fish swim together in a school, they actually reduce the total amount of energy needed. And by taking turns of who's swimming in front, that means that they save energy. And that is then a behavior that has been encoded and encouraged by billions of years of evolution. If we're looking at another animal, a modern animal, that is a researcher doing, say, artificial intelligence or deep learning, today we might be doing things like putting cameras and monitoring how fish are swimming. And then we might be administering different type of chemicals, drugs, and then adapting and catching patterns and see how the fish adapt to this and then draw conclusions about the behaviors. So there is a wealth of information you can do, not just on cellular biology, but even organism biology that uses modern methods founded in physics and computer science. That's not going to be this class, though. In this class, we're going to be mostly stuck in the other end. And in the other end of things, we have the molecules, and that's a world that I hope to introduce you to and that you too will see how amazing it is. So biology, in contrast to many provinces, is fascinating because we have so many scales. Looking here, we're starting from a tree where you might have scales of meters or tens of meters, even 100 meters in cases in the world. If we're zooming into that on a leaf, we might first be at centimeters. You're getting to millimeters where we're starting to see internal structures. You're eventually seeing cells below the millimeter level. And then we're starting to see organelles, parts inside cells. A tree is almost as complicated as a human cell, but they have slightly different composition of their cells. And somewhere very deep down, in this case, it's not even a microscope but a molecular model of it, we're having proteins that are at the ends that give these cells their properties and the way the tree works. So here we've probably had things spanning something like nine orders of magnitude in space, which is fairly impressive. We can choose to model this either top-down or bottom-up, depending on what we're interested in. So the top-down studies would be starting from the tree and then going down, but in particular with the advent of modern computers, we're increasingly able to study things starting from the molecules and then understanding how all of these molecules work together. Both approaches are powerful and they complement each other. We can start and make this complicated by doing it two-dimensionally too. So in this diagram on the x-axis, we have the scales, the length scales I talked about. Here we go even further because beyond the symbol three or something, you could think of humans, and in addition to one human, it would be scales of meters. You could even think of going to population dynamics. How does the population all over the world increase or adjust, for instance relative to disease or so? So that would be scales of kilometers even. But then we have corresponding scales here on the y-axis that has to do with scales in time. The fastest motions might then be something moving on nanoseconds, atoms vibrating inside proteins. We're going to spend a lot of time talking about that. But then we have cellular processes, proteins folding, maybe up to a second or so. The life spans of cells, eventually the lifespan of an individual that might be 100 years. And if we're thinking about evolutions, then we might be even talking about billions of years. So here too we have 9, 10 if not more orders of magnitudes that are spanning across both space and time, which I think is quite unique to biology, which it makes it complicated, but that's of course the fun aspect, and that's why we're doing research on it, because we don't know all these things yet. Let me take you down to the molecule level two. This is an example that we're going to get back to later on. So these are a couple of different small proteins, engines sitting in a cell membrane, and they're responsible for the energy turnover in your cells, part of it at least. So the green parts here are so-called ion channels that are fairly simple doors, windows that just open up, and when a door that fits a particular ion opens up, that type of ion will be able to flow through it. So in this case we have two different ones, one that's conducting potassium ions and another one that's conducting sodium ions. We're going to come back to what they do later on when we talk about the nervous system. These channels are fairly simple. So for something concretely to happen here, in a potassium channel for instance, you need to have an excess concentration of potassium on one side of the cellular membrane, and when this channel opens up, ions flow from the side where the concentration is higher to the side where the concentration is lower. That's a completely passive process that doesn't require energy. We're just equilibrating things. But that will of course lead to a nerve impulse. The reason we can do that though is that we're essentially using energy there, right? At some point we're going to need to charge up this energy. And that's done by the simple protein in the middle, which is not a channel, it's a transporter. It's a transporter that is moving both potassium and sodium ions at the same time actually against the concentration gradient. So this one is moving potassium ions from the side where the potassium concentration is low to the side where the potassium concentration is high. That's a process that won't happen spontaneously. And since it won't happen spontaneously, we're going to need to use energy, expand energy to make that happen. This is a very well-known protein and we even have structures of this. Jen's school got the Nobel Prize for this in 1997, I think it was. We even have a complete structure of this one, but before I show you the structure of the protein, I'm going to show you the structure of this. This is the energy. The ATP, adenosine triphosphate. That's typically how we store chemical energy for fast turnover inside the cells. There are some glycogen depots and everything where we store long-term energy. But by taking this molecule and tearing off one of these phosphate groups, we can release some of this energy. And then we turn the molecule into an ADP, adenosine diphosphate. The molecule I talked about, which is the sodium potassium ATPase on the previous slide, that one is using this process and using the energy stored in ATP to transport these ions across the gradient. And oh my God, is it using this a lot? Our bodies are turning over something in the ballpark of 70 kilos of ATP per day. It's of course reusing the molecules. That's why you don't have to eat 70 kilos of food. But there is an insane amount of energy being turned over in this and generated all the time. We'll get back to that. This is another important membrane protein, GPCR, G protein coupled receptor that is responsible for lots of the signaling in our bodies. So we're having different small compounds, drugs attaching here. The entire protein goes through a protein earthquake and this leads to a signal being transmitted to the inside of the cell where we have this G protein connected. This was one of the major advances in pharmaceutical structure determination when Ray Stevens and some colleagues were able to determine the first structures of them. The way we determine those structures is typically done with synchrotron light radiation, x-ray crystallography, that I'm also going to have a chance to talk to you a little bit about today. There are other ways we could do it though. Traditionally we would do this in the experiment but given the speed of computers and models under some conditions we can actually take this into a very fast computer and let the computer solve new terms equations of motions. In this case we're seeing a small ligand binding in a computer and what the computer is then doing on a femtosecond scale we're checking how things evolved and then you're going to see that the protein here actually changes its conformation and eventually there's a large conformational shift and in parallel with these studies we've actually been able to show that that does indeed correspond to the structure of the bound GPCR. So the computer here has been able to not just determine the right structure but actually tell us what's happening in the process which is an amazing new way that we can occasionally use to gain more understanding of biology. Now instead of doing that in the lab you're doing that with custom very large computers. There is a race in there both the US, Europe and China are investing tons of money in so-called excess scale computing that an insane amount of computational operations per second many of them are used for biology many of them are even used for our program, GROMACS and that you're going to be using a bit in labs later in the class. The question though, this is just a model and it's important not to fall in love with your model that's a theme that I'm going to repeat during this class and we need to check is that a correct prediction or an incorrect prediction and the reason I'm showing this one to you is of course that it turned out to be an amazing prediction. Sadly this was not me but the David Shaw group doing this. What you see here in purple the purple molecule here is the one that the computer predicted and the gray molecule is the post that was then later and confirmed in the lab and you see they superimposed perfectly. It's so good that you couldn't tell which one is which this is beyond the resolution of the experimental result. The reason why both academia and companies are investing so much money in this is that this is the way we discover new drugs. We start, well most of them we need to start with the structure of a protein and then we're identifying a small drug that combined and changed the behavior of this protein and just for the GPCR molecules here you have a whole bunch of drugs that have been discovered the last few years and then made it to the market. So while we're talking about this from a research point of view, physics and understanding things, this is very directly saving human lives and improving health all over the world so it's a quite direct way of improving human conditions. Although we're mostly going to stay on the molecular level in the class, occasionally we will go a little bit beyond molecules. So beyond molecules, you're having organization inside cells. Different proteins might go to different parts and compartments of the cell, for instance the nucleus or the endoplasmic reticulum and a few other things that we'll explain later in the class. Beyond individual cells, we also have different types of cells. A heart cell is not identical to a lung cell is not identical to a brain cell is not identical to a cell in the peripheral nervous system. We will talk a little bit about that but probably limited to the part when it influences protein structure. And beyond cells, we even have different types of tissue. So again, my heart tissue has one particular type of muscles that is quite different from the muscles sitting in my biceps and triceps. Another example where this is important is when it comes to drug design because when it comes to drug design, it's not enough to get those drugs into the gPCR receptor, right? Or rather once we are at the gPCR receptor, it's fine but somehow we're going to need to get the drug to the right cell first. That's a whole research area in itself that we will only have time to browse a little bit. Occasionally we can have drugs that we can eat as a pill but sometimes we have drugs that would be digested in your stomach and then we need to find a different way to deliver them. Sometimes we do it with injections but injections are complicated because you need to go and see a doctor and you likely you want to avoid infections is also an infection risk. In some cases we would like to go across membranes. The blood-brain barrier in particular is a very complicated membrane so even if you get the drug into the blood that might not be enough because the brain is not directly communicating with most of your blood. In other cases we would like an even simpler way of administering drugs particularly if you're not gravely ill.  We use them for contraceptives. We use them occasionally for motion sickness and those skin patches are pretty cool because you attach them to your skin and then they're gradually releasing a low dose of a drug over 24 or 48 hours. It's great because you don't get a very large dose immediately and we continuously administer it in a very nice and smooth fashion. The reason why that doesn't work for most drugs is that our skin is meant to protect us. It's not neither water nor oil will go through the skin. So this only works for a few drugs where we've been lucky. We have two very nice people sitting in my lab actually they used to be students and postdocs here but they formed a small company called Erco and they're doing research where they're trying to use computational models like you have here where they have models of skin that they have adapted to images of skin obtaining collaborations with the Carolina Skin Institute and then they're trying to use this to optimize both delivery mechanisms and see what changes the design of the drug to make it more likely for the drug to go through skin. Very advanced research but also an example of how fundamental strong research can somehow lead to obvious commercialization opportunities. I have to confess that I have a special love in the world and this love is membrane proteins so you're going to see lots of things about membrane proteins. This is arguably the world's smallest machine. If we talk about nano technology to be a bit blunt nano technology is what people say that they're using when they have 999 nm machines. This machine is in the ballpark of 10 nm it's just for alpha helices and it's the machine that is responsible for every single heart beat in our body. When the voltage across the cell changes one of these helices moves up and that opens one of those ion channels to let potassium ions through. This is another important machine I have here. This is a ligand gated channel that occurs throughout the nervous system. If you have a glass of wine on Friday what happens to the alcohol is that the alcohol will bind to certain proteins including this one and that will change how nerve cells mediate signals from the end of one nerve cell and how it's transmitted to the next nerve cell. It's not just used for alcohol consumption but also things like anesthetics and the whole use of neuropharmacological drugs that change our nervous system work is likely going to be able to target these molecules. We already know that anesthetics do and until 10 years ago we didn't have structures of them. We couldn't really design and tailor make drugs but today we do because of research. There are many other things that I would love to tell you about. Proteins are important throughout your body. This is a small protein called hemagglutinin which this wine flew a few years ago. You might have seen the name A-H1N1. The H in that formula stands for hemagglutinin and the wine is a particular sequence of that. That is literally the small drill that the virus uses to attach itself to the cell and releases genetic material into the cell. And in similar ways there is a whole wealth of different proteins that are enzymes. If there is anything that's happening in your cell and doing something actively it's virtually guaranteed to be a small protein and we're going to be looking at a bunch of these throughout the class. Another one that I think is worth looking at when I'm recording this which is spring 2021 is this. This is a protein that has become sadly super important the last year. So this is the so-called spike protein of the coronavirus and that's what gives this crown-like shape because it's expressed all over the surface on the virus. The blue part here and the corresponding part in the other monomer there it's a so-called receptor binding domain and that's a domain that attaches itself and binds itself to these domains which are actually not part of the protein but this is the DCE2 domain that is sitting for instance on my blood cells. So this is literally the way how the coronavirus attaches itself to my cells and with them help itself release its genetic material into those cells and a whole lot both of the small compounds we tried to design to combat the virus would try to inhibit this protein and the most of the vaccine candidates work by somehow introducing just this protein not the entire virus in your cells so that your cells would then create antibodies to this protein and if you then get infected with the actual virus the antibodies will recognize the spike protein and kickstart your immune defense system to get rid of the virus. The class here is going to have a number of desired learning outcomes and I would say that there's two or possibly even three there's a bunch of fundamental knowledge I want you to understand how these biomolecules work I want you to be able to reason and explain different parts of protein structure we want you to be able to reason about dynamics we want you to be able to understand the hierarchy of molecular structure I don't think I mentioned drug design there so there are a number of fundamental basic knowledge that it's important for you to know even by heart because if you don't know it by heart you won't be able to have a brainstorm and reason about it and then there is a second part that you need an ability to synthesize information using all these knowledge there is a saying that to be successfully live research anything you need good judgment and you get good judgment from experience and you get experience from bad judgment hopefully I can help you save a little bit of time there so you don't have to gain so much experience through your own bad judgment but that you can borrow the bad judgments of previous generations of scientists but it's important to sit down and think about things and work with it to get to these second parts that enables you to be an independent strong scientist merely knowing things by heart that's important it's necessary but it's not sufficient to be able to perform research or be successful say doing drug development and industry yourself but we will start here and we will gradually get to the abilities later on in the class we are going to be speaking a lot about protein structure we're going to be speaking a lot of protein folding much of this is going to be starting from physics we're going to repeating something called sequence leads to structure leads to function the central dog molecular biology and gradually we're going to be talking a little bit about protein engineering not so much from an engineering point of view there are much better classes to do that from a practical point of view but I'm going to cover the reason why things work and we're going to cover that from a physics point of view going all the way to fundamental concepts such as free energy so the reason I love this not just this class the entire field I'm doing research in is that I find it a beautiful mix of chemistry biology and physics we are going to talk about basic concepts today a lot of it's actually going to be water which is more important than you think we're going to be speaking about DNA and RNA we're going to be speaking a little bit about protein production machinery and protein structure but that we're going to do a separate concepts


Everybody forced here ripping 22 23 select the Liga 4 box number 9 random teams so you'd find these results anytime late sports cars Dot-com we're gonna get right to it Now here's where the here's with the good names are done. There's the the tougher names are Liga Sapphire's breaking next has nine to go. We got to get it filled got to Got to Silver terrace level rookie is Sir Don Bob each For El Maria with a purple rookie or not rookie, but purple mezzanine is Baron Shia It's a 75 for associated No blue mezzanine is Roque Mesa by Adolid Pablo. I'm are on the Valencia auto Let's see out of Pablo. I'm are Paulo That's it, right? 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Yeah Sapphire down to one so dual case is at night to go now to nice We'll see occasion. I got a haircut. I haircut dude So I literally cut my hair No, we never played if we don't Donny night literally cannot play for tonight Yeah, it's like during the day at some point. That's a holiday of forces Purple mezzanine Niko Williams for athletic club. So there's a Neko Williams for Nottingham Forest and Premier League and there's a Niko Williams for athletic club They're both kind of like it's like Neko and then you go. Yeah Okay, so the ease just one of the do it mezzanine rad Moriba for Valencia. I'll generally just one of the do it Just break up the hat now. It's very cold in here now. I read Tara Saville Espino I went with the lowest amount of hair you could possibly have all still having some sort of hair Pretty much the cut Jeremy Pino on the auto for Villa Rial My hats are all loose now.  It's very loose round. We got the pile front Lettico and Zebra All-Sgar Trejo for Viacano to 25 Can't tell the difference Reflections throwing out the white balance That's funny. I'm having a Rio Madrid patch guard. It's like the most fun name to stay in the set Silver Levin Dovsky field level Barcelona Barcelona Levin Dovsky I don't think it works like that actually I think it has to be like that C. Not even like the S. It's like that. It's like the C Silver Tara Silver rookie Fernandez. I'm a Ria and a white mezzanine for a vorham How do you say that? mayoral My mayoral to 20. I believe that's how you say it for get off a illegal said howdy top of the morning Diego Costa let's you go Madrid Jersey card Yeah, there is a likes it So it's a sub rookie yon cuto for Geronimo. You said morning like that I'm so in Brian. I was doing money. Oh, yeah, when he has the disguise for the morning What up you see Thank you. Good luck, man. Silver mezzanine Tony Cruz Real Madrid Tony Cruz is funny to say too You got them ballet Barcelona try color Barcelona and purple come a venga field level again This time is the book end 75 or 75 Real Madrid crushed it.  I had a green show a mani Grats Real Madrid. That's the five on the unstoppable insert early on to a mini relics of Diego Costa come a venga Ferentores morata ferentores pk racket itch autos for a real real was Pino Real Madrid Carvalho and Laudrup Come a venga Real Madrid redemption Pitsite signatures Game-worn patch I don't eat your money on for athletic club the Belgian Atlético redemption David De Gea select signatures La Liga. That'd be a cool. That'd be that's a pretty cool one actually Things what Steve said he's been out of La Liga for like a decade now. That's pretty sick Nice one at let's you call Madrid and Pablo. I'm are on the plenty auto. That's gonna do it Thanks, everybody. We are moving on to baseball


Hello everyone, we're talking about deadlifting safely without hurting your back and today I want to go into a little bit of more of a humility talk, so Don't use too much weight. I You know I my buddy Brandon Brown had this really good slide one time that he gave a kettlebell And this was just for a squat, but he gave a woman a kettlebell to squat with 12 kilograms perfect 14 kilograms round-back city Sometimes the weight is just too much and that is true in the deadlift. It's true in any different movement sometimes You're you know, even though that woman could squat that weight I would argue that it's too much because she cannot maintain good technique while she does it Now you'll get a big comeback that you'll get is One rep max is never really look good, but I would just say that you're not progressing correctly I've I've seen more and more people be able to Hang on to really good positions for a really long time But it took them a long time to learn that they have a lot of reps under their belt That have taught them how to deal with fatigue and how to maintain good positions while they're fatigued so Keep that in mind Don't use too much weight if you can't figure out you're watching one of these other videos in this Lance Goyki playlist that you found and Stuff is not working. See I didn't swear there. That's good. I'm getting better Stuff is not working then consider the fact that maybe you need to take the weight down and Just kind of you know Swallow your humble pill and figure out the positions first Then from there Absolutely add more weight on okay, but you have to demonstrate to me that you can do it Effectively with you know a relatively small amount of weight Before I'm gonna start loading you up before I even you know a good example of this is when I'm teaching this I'm usually teaching a kettlebell deadlift variation because kettlebells only get so heavy But you're gonna need to show me a really good kettlebell deadlift before I move you to a trap bar deadlift or a barbell deadlift One caveat I want to talk about if you have someone who's a little bit fitter And you're trying to figure out how to clean something up Maybe you've been deadlifting a certain way Maybe it doesn't look very good and now you're trying to fix it You might have strength and you might have Fitness, but you might not have the motor pattern and so especially if that person is pretty flexible I might actually increase the weight to make it easier Sometimes you just need a little extra sensation a little extra compression to help you out With a with a you know kettlebell If you get someone who maybe looks like me they obviously work out a little bit, but They're definitely pale. I might give someone like me a 24 kilogram kettlebell most 100 to 90 to 140 pound women I'm giving maybe a 10 kilogram 8 kilogram kettlebell just to start at Anybody who's got back pain. I might be starting you again with you know, like an 8 kilogram Maybe a 12 maybe even a 16 if you look pretty fit And we're gonna dial it in from there If you look like you're not struggling with it You you're not struggling with the weight You just can't figure out the movement then I might go up a little bit But if you look like you're struggling with the weight and your shoulders are collapsing and your weight is shifting forward Then I'm concerned then I'm thinking okay This is maybe too much weight and that is most often the case though as I mentioned sometimes You might need just a little bit more


What's the word, y'all? Now, to be honest with you, I know I say this pretty much every offseason. But this one right here could be legendary. And I and I'll try to convince you of the case because I said this a little while ago to the homies, they were like, who's in this free agency class? We ain't got no Kevin Durant, we ain't LeBron, it's not a free agent. We not going to see no super duper stars, which seem through free agency. But we could see some crazy things happen through trades. We have again, we have free agency, which is there's no big names, super big names out there. But we could see some really, really good player switch teams.  We got the NBA draft, which every single year brings a bunch of drama. And then we got these new rules and basketball that haven't gone under the radar for everybody. If you're a super NBA nerd, you understand the NBA salary cap apron, the second one that was just put in play with the new CBA. But all of these things can make for ridiculous offseason. I'll explain why. After I tell you that the enjoy basketball, Icy collaboration is live for sale right now. Hit the link in the description. Growing up, Icy was something that I had pretty much as often as I could. So to be here with my own brand, collaborating with them is a dream come true. So we got this basketball that I don't know if you would want to take it to the court or you just want to use it as a set piece, which is what I'm going to do. Either way, this ball is perfect. We also got the slurpy slushy cups, which is dope.  We got the hoodies. I'm wearing the hoodie and the t-shirt under the hoodie. Like I'm geeked right now. You know what I'm saying? I might not take this off for a couple of days, but it's a huge back piece that has a polar bear with the enjoy stuff. Again, these things are on sale right now, and it is very, very limited. So I appreciate everybody that's been interested. Get in while you can. I want to say thank you to all of y'all because if it wasn't for y'all selling out in our first, second and third drop, IC brand would have had no interest in collaborating with us. So if y'all show love, man, it could open up so many doors for not just the enjoy brand, but just in general. So I appreciate all the support throughout the years. And this again, this stuff is so very cool to me. Oh, if you do buy something, hit me up on Twitter and Instagram with a screenshot. Please blank out your address because I don't want to dodge you. But I do want to show my love to the people that are also showing love to the brand. So hit me up. All right, where do we start? Where do we start when I when I try to convince you that this office is about to be crazy? Maybe we start at the at the individual teams that I'm the most interested in come off season. The first one being the Los Angeles Lakers. Now, we talked about them a little bit yesterday and this potential offseason. So I won't go too deep into it. LeBron James, before I recorded or after I recorded that video, threatened to potentially retire, which changes a little bit of things. But I've seen a lot of people speculate that that was more ploy to kind of get them to go completely in at his age. Thirty nine year next year. I don't know what's going on in that man's head. So is he actually thinking about retirement or not? I don't know. But this could be an interesting offseason for them, regardless of whether he he retires or not, because they only have Anthony Davis, LeBron James, Max Christian, Jim Vanderbilt under contract right now. Even LeBron James knows that in his post game interview. So he's thinking about what the next iteration of this team looks like. I know they might be interested in some one of the top players in this creative class. I don't know what it looks like, but right now you got four guaranteed contracts and the opportunity to flip the roster again, which is kind of a LeBron James thing. But we, we have a couple of players that we in love with, but everybody else y'all can be gone so we can put in the right pieces here. So I'm excited about what they do. Number two on this list is the Philadelphia 76ers slash Houston Rockets, because right now they attach like this, where I say like every single day I'm going to new update about this potential anonymous general manager, a scout saying that, that James Harder going back to Houston is set in stone already as a guarantee in the Charles Barkley voice. So if he's gone guaranteed and in this, this hypothetical that is a guarantee, the 76ers get nothing. This is not a sign of trade opportunity because why do the Houston Rockets want to help Daryl Maury after what happened between them? Why do they want to send out some assets to, to the 76s to make them a little bit better? They don't have to do that. So James Harder walks completely what's next for the 76ers? I should have low key opened up with this team, the Portland Trailblazers. The Portland Trailblazers have one of the most intriguing off seasons ahead of them. Obviously, they were bad this season and they, they leaned into the tank, ended up with the fifth best odds for the NBA lottery, ended up jumping all the way up to number three. But number three, it's not Victor and Myanmar and they said if they aren't getting Victor and Myanmar or speculated that if they weren't getting Victor and Myanmar, they would be interested in trading that pick and Anthony Simons and whatever to try to bring in some people that can help Dame right now. And when all of this went down, there's a lot of conversations on Twitter about maybe the Portland Trailblazers should accept the reality of Damian Lillard, this not doing it, this and this and this. That's not so relevant to me. I am just excited to see if you are trading three and Anthony Simons or three by itself or Anthony Simons by himself, what is the move that you can convince your fan base is the right move for Damian Lillard to get into contention. Again, I've said many times on this channel over the last year or so, I will not come here and say trade Dame because if Dame don't want to get traded and the front office don't want to trade Dame, I'm screaming into a void if I say trade Dame. So I've accepted the fact that Damian Lillard is going to be a trailblazer until he decides that he doesn't want to be anymore, even if keeping three and potentially moving Dame might be a good, a good thing to do if you want to hit the reset button. But again, that's not what they're thinking right now. So I'm not here to try to make them do it because what, what say, do I have, but in the 2k mode, like if I was going to do something on 2k, the idea of trading Damian Lillard and keeping three is super intriguing, especially if at number two, Brandon Miller goes and now I'm getting to school Henderson. Again, I don't really know. What makes it even tougher that like, like if they decide, if the treblets decide, okay, Dame, we love you for the last decade plus you've been the best player franchise history between you and Clyde's who cares. We're going to see you to your next team. We appreciate all these years. Look around the league as good as Damian Lillard is, and he would be better than a lot. He's bet, the best, one of the best point guards of basketball behind Steph Curry. Um, a lot of teams right now probably feel pretty confident and who their point guard is at the moment. And I'm not saying that these teams wouldn't appreciate Dame's services, but I'm just saying for what the Treblets would potentially want, a lot of the teams that you would want to send Dame to so he could compete for a championship aren't really in the conversation for Dame. Like the 76ers would be interested, but right now they don't really have assets for Dame. So it's like, if we are going to trade Dame, what is the location show, show me the team that has the assets that would they be willing to give up, but also be still good enough where they can convince themselves that Dame is the missing piece because there are a lot of teams that have assets, but you'll be putting Dame in a very similar situation the way he's at. So that's what makes it really tough. And again, I don't envy the people in charge over there, but we'll see very, very soon where their head is that when it comes to that pick and depending on what they do with it and depending on who comes out at number three, whether it is Brandon Miller or school Henderson, we can look back on that trade of five years and say, this team absolutely wanted and this team absolutely lost it. I don't know. And another big team in this is the Boston Celtics, especially, especially if they end up losing this series. I should have mentioned this at the top of the show. Celtics fans, I know you won tonight, which is dope for y'all. I'm not going to be here breaking down the series again until you win game five. Now, if you win game five, you make it a three-two series, then we can start talking about y'all being the first team in NBA history to come back to 0-3, but I'm not looking at this one game and dissecting this one game when you just lost the last three. The reality of the situation is, for the first time in this entire series, you shot the ball like you normally do. That's the reality of the situation. You hit a lot of shots, the Miami Heat did it. Sometimes it's that simple. Now, can you replicate that again and then again and then again to become the best team, the first team to ever do it? Maybe, but until we get close to it, I'm not about to sit here and dissect it because what I had to say is all I had to say. But back to the off-season, if they do end up losing here, and Jalen Brown's made an all-to-be-a-second team, and he's supermax eligible, he can make potentially $300 million. Yes, and Tayden can potentially make $300 million. Do you want to tie $600 million to two singular players? And again, the lesson is Jordan and Pip that's guaranteeing you six of them things, $600 million a lot, and even Jordan and Pip, Pip was making pinnics, pinnics on the dollar. So $600 million is just a lot of money, especially if you have this team. And even though he's 26 and the other one is 24, and they got a lot of room to grow and potentially grow together, it hasn't been able to raise Lario Bryant's trophy yet. So if they end up flaming out and Jalen Brown has his mindset on a different organization, he could be one of the best players moved this off-season. And those are just the teams that I think have a lot going on from this off-season. I didn't even mention the Phoenix Suns have a Chris Paul DeAndre, Aiden and potentially maybe moving on from one or two of those people. I mean, we got teams on a lesser scale that have a lot of systems like the Dallas Mavericks, like the Chicago Bulls. Like these are teams that we don't see as championship contenders, but they have pieces and stuff that can maybe get moved that can shake up the NBA. So that's why I'm saying this off-season has the opportunity to be one of the ones where we look back on the rosters from this year and compare it to this next up and come a season you like, dang, a lot of things have changed. And personally, I love change. My whole gaming channel is about people switching rosters. I built the name on YouTube around that, you know what I'm saying? I love when it happens, especially when you see a move that impacts the team so much that it is the missing piece for them to win a championship or something like that. That's what we're here for. So you let me know what you think. What is the most important decision your favorite team has to make? Go ahead and enjoy some icy, enjoy basketball, merch, and stuff and let me know what you think. And I'll see y'all tomorrow. Peace.


Good morning everyone, I'm Y1 Guilherty, the CFL here at the Naval War College and today for our virtual workout we're going to be doing the upper body. So let's go ahead and get ready to get started. So our first exercise is going to be 4 sets of 10 regular push-ups followed by 5 sets of slow push-ups. So regular push-ups to demonstrate, we want to get down on the deck like so, we put our hands in front of us just like this, shoulder width apart, we'll come up, put our feet together and then come down. Just like this you want to break 90 and again we want to do 10 regular push-ups and then follow up by 5 slow regular push-ups. So just come down just like so and come up and one more time and that's going to be 5. So our next exercise is going to be 4 sets of 10 wide grip push-ups. So you're just going to go on the deck and your hand's probably out this far apart and we're just going to go just like this and again 10 wide push-ups. Alright so our next exercise is going to be 4 sets of close grip push-ups. So for the close grip you want to put your hands down like this on the deck and you're just going to push up and down just like so and again that's going to be 10. Alright so our next exercise is going to be 4 sets of 15 four count jumping jacks. So just like so we start off in an attention spot and we go up and just like in this motion. So the count will go 1, 2, 3, 1, 1, 2, 3, 2. Again we'll do 15 of those. Alright so our final exercise is going to be 3 sets of 30 second push-ups followed by 10 seconds of rest followed by another 30 seconds of push-ups. Again so like we demonstrated just come down on deck like so, go down and break 90. Again that's going to be for 30 seconds, 10 seconds of rest, another 30 seconds of push-ups. Again 3 sets of that. Alright thank you all for viewing our workout, I'm Y1 Guillory, signing out, we'll see you next time.


Hey, the time has come for you to get on camera for your Redback webinar right here in our state of the art studios in Sydney. We do things a little differently here at Redback, so in this short video we'll explain how we run our webinars, what will be expected of you and what you can expect from us on the day. Firstly, we are located at level 768-70 Dixon Street Haymarket which is right in the heart of Chinatown and the closest stations at Town Hall and Central. We recommend arriving at least 45 minutes prior to your event to ensure you're fully prepared. Once you and your fellow panellists arrive at level 7, pick up the phone to let us know you're here, then go through some of our social distancing and hygiene practices including a temperature check, signing in and using a hand sanitizer. These steps will help ensure the safety of our customers, guests and team members and yourself. You will then make your way into the studio where you'll be greeted by one of our delivery technicians and you can run through your presentation together. You will be miked up, will be provided with a clicker to move through your slides and will also give you an iPad for taking questions from your online audience. If this is your first time presenting from a studio, don't stress. Our technicians will be with you the entire time so you can focus on what you do best, presenting amazing content. And that just about covers it. If you have any other questions, simply ask your customer success manager. We look forward to having you in the Redback studio soon.


Sorghum is the forgotten grain. The United States is actually the number one producer of sorghum, but it's typically not used to produce food for American consumers instead. It's produced mainly for feeding livestock, or as pet food, or even building materials. But it's actually eaten as a staple in other parts of the world, such as Asia and Africa, where it's been eaten for thousands of years, making it currently the fifth most popular grain grown after wheat, corn, rice, and barley beating out oats and rye. Because sorghum is gluten-free, because it can be definitively considered safe for people with celiac disease, we're starting to see it emerge as actual human food in the US, so I decided to look into just how healthy it might be. Protein-wise, it's comparable to other grains, but since when do we have to worry about getting enough protein? Fiber is what Americans are desperately deficient in, and sorghum does pull towards the front of the pack. The micronutrient composition is relatively unremarkable. Here's how it rates on minerals, for example. Where sorghum shines is on polyphenol content. Polyphenols are plant compounds associated with reduced risk of a number of chronic diseases, including cancer. Cardiovascular diseases, neurodegener, disorders, and even all-cause mortality. And if you compare different grains, sorghum really does pull ahead, helping to explain why its antioxidant power is so much higher. Now, sorghum gets its grainy little butt kicked when it comes to fruits and vegetables, but in terms of compared to other grains, sorghum-based breakfast cereal, for example, might have like eight times the antioxidants than a whole wheat-based cereal. But what we care about is not antioxidant activity in a test tube, but antioxidant activity within our body. If you measure the antioxidant capacity of your blood after eating regular pasta, it goes up a little. If you replace 30% of the wheat flour with sorghum flour, it doesn't go up much more.  See, there are multiple types of sorghum. There's black sorghum, white sorghum, and red sorghum. This is how they look in grain form. There's evidently a yellow sorghum too. And red sorghum, and especially black, have like legit fruit and vegetable level antioxidant activity. The problem is I can't find any of the colored ones. I mean, I can go online and buy red or black rice, purple, blue, or red popping corn, and purple or black barley, but I can't find red or black sorghum. Hopefully someday, but you can find white sorghum for about 4 bucks a pound. I mean, it doesn't have any unique health-promoting attributes. It's promoted as an underutilized cereal whole grain, with the potential to assist in the prevention of chronic disease. But what is the effect of sorghum consumption on health outcomes? An epidemiological study in China found lower esophageal cancer mortality rates in areas that ate more millet and sorghum compared to corn and wheat. But that may have been more due to avoiding contaminating fungus than from the benefit in the sorghum itself. I mean, though it's possible. I mean, just as oats are the only source of avanathomides, which give oats some unique health-benefit sorghum, even white sorghum can attain unique pigments, known as three deoxyanthocyanins, which are strong inducers of some of the detoxifying enzymes in our liver and can inhibit the growth of human cancer cells growing in a petri dish compared to red cabbage, which has just regular anthocyanin pigments. But note that white sorghum didn't do much worse than red or black, which have way more of the unique three deoxyanthocyanin. So maybe it's just a general sorghum effect. I mean, you don't know until you put it to the test. Sorghum was found to suppress tumor growth and metastasis in human breast cancer xenografts. What does that mean? The researchers include that sorghum could be used as an inexpensive natural cancer therapy without any side effects, strongly recommending the use of sorghum as an edible therapeutic agent possessing tumor suppression and anti-metastatic effects on human breast cancer, but xenograft means human breast cancer implanted in a mouse. Yes, the human tumors grew slower in the mice-fed sorghum extracts and blocked metastasis to the lung and did the same for human colon cancer that, again, was in mice, which can't necessarily be translated to how human cancers would grow in humans, since, for example, not only do these mice not have a human immune system, they hardly have any immune system. They're bred without a thymus gland, which is where cancer-fighting immunity largely originates. I mean, how else could you keep the mouse's immune system from rejecting the human tissue outright? But this immunosuppression makes these kind of mouse models that much more artificial and that much more difficult to extrapolate to humans. And that's a lot of what we see in the sorghum literature in vitro data, like in test tubes and petri dishes and rats and mice. There had just been this critical missing piece of the puzzle needed to link laboratory data to actual benefits in humans missing. That is, until now. Thankfully, we now have human interventional studies which we'll explore next. Despite playing a significant role in African Asia as a staple grain, sorghum has only recently emerged as a potential food source in the US. It's not just a principal grain in many parts of the world, but evidently used in folk medicine traditions. What might its health benefits be? There's been some in vitro data from test tubes and petri dishes and in vivo data, meaning within the living and laboratory animals, but only recently have we started seeing human trials. In one study, subjects were asked to eat sorghum pancakes versus corn pancakes for supper for three weeks, and both groups saw huge 20 to 30% drops in their cholesterol, but they were also well told to not eat eggs and other cholesterol-boosting foods, so that may very well have been playing a role. Another study tried biscuits. Those eating sorghum biscuits said they felt more satiated than eating wheat biscuits, but this didn't translate to differences in intake at the subsequent all-you-can-eat meal, so who cares what they subjectively felt if it didn't cause them to eat any less? It's no wonder then, when you put it to the test, those eating sorghum versus wheat biscuits didn't lose any weight. The data is a bit mixed. A recent study concluded that sorghum can be an important strategy for weight loss in humans, though the sorghum group didn't actually lose more weight, but they appeared to be eating hundreds more calories. They yet lost more body fat, perhaps because of their greater fiber consumption or other goodies like resistant starch in the sorghum. The vehicle they used, though, an artificially flavored, colored, and sweet mixture of water, powdered milk, and either sorghum or wheat, may be good research-wise, so you can make a blinded control, but it leaves you wondering what would happen if you actually ate the whole food. The resistant starch is exciting, though. I mean, most of the starch in sorghum is either slow starch or fully resistant to digestion in the small intestine, which offers a banquet bounty of prebiotics for your good gut flora down in your colon. It's not evidently the sorghum starch itself, but interactions with the proteins and other compounds that effectively act as starch blockers, inhibiting your starch-munching enzymes. Sorghum then ends up with the lowest starch digestibility among grains, which is why, traditionally, it was considered an inferior grain, but inferior in the sense of not providing as many calories, but not providing as many calories is a good thing in the age of epidemic obesity. Give someone a whole wheat muffin compared to a sorghum muffin, containing the same amount of starch and see significantly higher blood sugars 45 minutes to 2 hours later, and a higher insulin spike starting almost immediately. Overall, a 25% lower blood sugar response, and the body only had to release a fraction of insulin to deal with less than a half. Same thing with diabetics, lower blood sugar spike with a sorghum pour is compared to grits that the body can deal with with a fraction of the insulin. So, we need to educate people how healthy sorghum is, and develop convenient, tasty products? No, it's already convenient and tasty just the way it is. I mean, one button press on my electric pressure cooker with two parts water, one part sorghum, and it's done in 20 minutes.  But where's the money and people eating the intact whole grain instead? The industry is looking at sorghum for its enormous potential for exploitation into so-called functional foods and food additives. Or, I mean, did you know adding sorghum to pork or turkey patties can decrease their cardboardy flavor? And hey, why just eat it when you can instead use it to make gluten-free beer?  When I was talking about taxpayer subsidies to the sugar, corn syrup, oil, and livestock industry, subsidizing cheap animal feed to help make dollar menu meat, I jokingly asked, you know, when's the last time you sat down to some sorghum? But hey, now that I know how good it is for you, maybe we should be taking advantage of the quarter billion we're spending to prop up the industry and sit down to some sorghum after all.