Welcome to the Dr. Gundry podcast. Ask almost anyone over the age of 50 what medical condition they most fear and probably all of them will respond with the same answer, Alzheimer's disease. And that's no surprise since it's now the third biggest cause of death in the United States. And depending on estimates over 75 to 90 million Americans are actually genetically predisposed to get it. In fact, I'd wager that almost everyone listening to this podcast knows someone and maybe has a family member who has suffered from Alzheimer's disease. Well, my guest today says there's no reason why Alzheimer's can't be a rare disease, one that we can nearly eradicate. Imagine that the same way we once got rid of scary diseases like polio and leprosy. So I'm joined by my friend and colleague Dr. Dale Bredesen. He's professor of molecular and medical pharmacology at UCLA, the author of the New York Times bestseller The End of Alzheimer's and like I mentioned he's become a good friend of mine through the years. Dr. Bredesen has a brand new book out launching tomorrow the end of Alzheimer's program, the first protocol to enhance cognition and reverse decline at any age. It's all about the lifestyle changes you can make to prevent and even reverse symptoms of Alzheimer's disease. And on today's episode, he and I are going to discuss the APOE-4 gene, what your blood sugar levels have to do with dementia and which diet plan is best for brain health. Dale, happy to have you back on the Dr. Gundry podcast. Hey, great to see you, Stephen. Great to talk with you as always. Alright, so what's new in The End of Alzheimer's program? How is this different from the last book? Yeah, great point. So the first book, The End of Alzheimer's, was really a conceptual book. So this looked at our 30 years of research in the lab, what happened with the transgenic mice, what happened with the bacteria, what happened with the cells. And moving forward, we started with the idea of these diseases, neurodegenerative diseases, as you know, Stephen, have been the area of greatest biomedical therapeutic failure. You know, you did all this great work with hard bypasses and all these wonderful things over the years. We just haven't had anything for neurodegeneration. So whether it's frontotemporal dementia, Alzheimer's, Lewy body, ALS, there just hasn't been anything. So we were looking at, could we understand the molecular basis well enough so that we could begin to fashion the first effective treatments. And as you know, we ended up coming circuitously over these many years of research and realizing, wait a minute, this is not a single drug disease. This is a many different component problem where you actually have to change network function and your network is related to your neuroplasticity in Alzheimer's. So when we published that, a lot of people said, hey, we want more details. What are the URLs? What are the workarounds? What brands do we buy? Where do we go to the store? All these detail issues. So that's, this book is about the details, whereas the first book was about the concept. And so I'm very excited because for the details, I worked with two wonderful ladies. My wife, Dr. Aida Lashine-Bretison, who is a clinician, and with Julie G. And Julie, you know, is a wonderful user and biohacker and someone who's now been on the protocol for over eight years. And perhaps the most important thing is, as you know well, when you get better, you stay better if you're getting at the root cause of the disease. Whereas if you're trying to circumvent physiology with a drug, you just go right back to declining again. And in fact, as you know, article published about a year ago showing that people who were on the drugs actually did worse overall than people who were not on the drugs. So this one is really about the details. How do you do it? It's the program. So, you know, we've talked about this. Why do you think mainstream medicine has failed in this? A lot of money has been thrown at this. Yeah, billions and billions of dollars, as you well know. And this has been the problem, I think. And you know, it's interesting, your career shows it. You had the first part of your career, where you did very standard medicine, as did I as a neurologist. And then you said, wait a minute, there's something else out here that actually works better. And you've devoted the rest of your career with it. You know, you made a fundamental change there. And you know, it's interesting to me, this is exactly what happened to us. We are following the test tube research. And we are following, okay, wait a minute, here we see that amyloid precursor protein is acting like a molecular switch. It can switch you towards synaptoclastic activity when things are bad, you're pulling back. But it can also switch you towards synaptoblastic activity, when things are good. Okay, let's look at what those things are. And in a mouse, we can make a genetic change, change everything.  So we realized to change that network of neuroplasticity in a human brain requires that you evaluate, which as you know, doctors haven't been doing, you evaluate the critical parameters, and then you address each one. The assumption is kind of stuck in 20th century medicine is what classic medicine has been, including all the pharmaceuticals, assuming making a huge assumption that a single drug will cure all of the ills of a complex chronic illness. And it actually makes no sense. No, you're right. In fact, I know we've mentioned this before. A few years ago, I was asked to come to major Alzheimer's University Center and give a lecture. And the head of the program after I was about 20 minutes in, he says, Well, this has nothing to do with drugs. And, you know, everyone knows that drugs are the only hope in treatment of Alzheimer's. And thank you very much, Dr. Gundry, but I don't want to hear any more about this. This is this literally happened. Oh, my gosh. Yeah, it's, you know, it is amazing to me, people will literally stand there, knowing the truth, and just say, you know, this is not what it is. We've got in fact, some of the crazy comments we've gotten are the drug companies will never go for it. You know, the FDA doesn't like a multivariable approach. You can't do a clinical trial with more than one variable. I mean, it's just amazing. In the face of people getting better and being published, we published 100 so in 2018, we published 100 patients with documented improvement, improvement in electrophysiology, improvement in MRI volume metrics, improvement on their quantitative cognitive assessments. But in the face of that, people simply deny it. We're going to go after the drug. And as you know, one large group has said, you know, someday out there, we want to find the first survivor. Well, there are hundreds of them. You're seeing them. I'm seeing them. So many people are seeing them. And they're literally denying the existence of these people. Yeah. All right, so there's a lot of people want to know about the apoE4 gene. Yes. Why do why do so many people carry it? And how is it connected to a higher risk of Alzheimer's? Yeah, Steven, great question. And you know, I think that the apoE story is one of the most interesting stories in medicine. As you know, it impacts your field of cardiovascular disease. It impacts your longevity. It impacts, you can own, you know, people have called it the God gene because it impacts so many things. Of course, it is the most common risk factor for all genetic risk factor for Alzheimer's disease. So to make a many year story very quick, apoE4, as you know, the apoE comes in two, three and four, and you get one copy from your mother or one copy from your father. So for example, I checked myself, I'm a three three, which is kind of the vanilla. It's the most common thing. My wife is an apoE2 three, which actually gives her some decreased risk. So she's very fortunate for that. And so I told her, you know, you're going to be taking care of me, sweetie. And hopefully, if I do the right thing, that won't that won't come to pass. But as you know, the story is fascinating because in our in our forerunners, the simians, the simians had apoE simian basically, which was different. And it underwent a few mutations to become our primordial. The original hominid apoE is apoE4. So for 96% of our evolution as hominids, we have all been apoE4 for the one that is the highest risk. And today, if you have zero copies of four, your chance during your lifetime of getting Alzheimer's about 9%. If you have a single copy, about 30%. If you have two copies, well over 50%. More likely you will develop it then that we will avoid it. Of course, we'd like to make all of those zero by doing the right things. So there is a fundamental difference in these molecules, they look different, they act different. And of course, one of the things about apoE4 is that it increases your your inflammatory response to virtually anything. So just as we've been hearing so much in COVID-19 about the whole issue of cytokine storm and the whole issue of inflammation as being a real determinant, of course, Alzheimer's same story. Inflammation is huge. But what takes decades in Alzheimer's COVID-19 has compressed down to two weeks, as you know. So what happened was, it's only 220,000 years ago that apoE3 appeared. And then 80,000 years ago, apoE2 appeared. Now some believe that apoE3 then thrived because it was after we had fire and things like that. The bottom line is we don't know. But for whatever reason, we have a less pro inflammatory gene. And as Tuck Finch, the professor from USC has pointed out, that inflammation was probably helpful five to seven million years ago when apoE4 appeared, because we were stepping on things, stepping on dung, we came down out of the trees onto the savanna.  So you need a pro inflammatory gene just for survival. We don't need that in the first world today. And by the way, as you know, in the third world, you still need that if you go down to the Chimane Indians in Bolivia, what do you see they in fact do better with apoE4 because they're all they have many, many parasites and things. Exactly. So what what we found, which was really striking, and we published this a number of years ago in the lab, everybody was wondering, how does apoE4 the thing that carries your lipid around? It's it's like your butcher, it carries fats. How does that give you Alzheimer's disease? And what we found really surprising, apoE binds to receptors that had been known. But the surprise was it actually enters the nucleus, not all of it, but a significant fraction of the apoE enters your nucleus. And apoE4 interacts with 1700 different promoters. So it actually changes the programming of your cells to among other things, a more pro inflammatory state. So it affects, for example, things like tumor necrosis factor. So you acting now again, that's great when you need that inflammation. But in the long run, what you want to do is keep that down so that you'll live a longer life without Alzheimer's without cardiovascular disease. So that's why apoE4 gives you that risk. So how do people find out if they carry it? Very simple. You can go on you can either go to 23 and me and check very easily. You can go on mycognoscopy where we do a whole looking at all the different critical pieces that give you risk for Alzheimer's disease. And then one of the many things, in fact, is apoE4. So you get that and you also get your, you know, HHS, CRP, vitamin D, all the things that we know are putting you at risk and are contributing to that beautiful balance that your amyloid precursor protein makes. So I, you know, I check apoE status on all my patients when they walk through the door. And, and some of my patients say, I don't want to know if I have it. What, what say you about this? Yeah, this comes up all the time. I think it's very important for people to know their status. So I'm glad you're checking it. And, you know, the reality is, everything has been upside down in the Alzheimer's field, because it's based on we can't do anything, don't know, don't help put your head in the sand, and it'll happen to you one day, and you won't be able to do anything about it. And it's just the opposite of that now, the truth. So in fact, people tell you, the armamentarium is nothing. There's nothing you can offer that does anything. In fact, the armamentarium is huge.  So everybody should know their status. Now, again, we're told, Oh, don't check your status because there's nothing you can do about it. Yeah, check the 3,500 people on ApoE4.info who are all doing a tremendous amount about it. Yeah. And I think that's the point of this book. And you've done a great job of really saying, Okay, I'm glad you have ApoE4. And because here's the steps that we now know that you can mitigate this. So what Okay, so let's suppose and again, 30% of Americans carry at least one copy. And so this is not a freak little thing. Right. So what give me kind of step us through what can people do who particularly are carrying this gene do you know today with your program where where are the steps? Yes. Great question. And of course, Julie G is herself an ApoE4 force. She's almost like it. And she has taken her own cognition from 35th percentile to the 98th percentile where she remains after eight years and doing just absolutely beautifully. So you know, she's living proof as well as many other people that there is a tremendous amount you can do about this. And so start by saying, Okay, this is not a disadvantage. It's an advantage in certain areas. As you know, you're better at fat absorbing, you're better at dealing with various infections. You know, just this is probably why we did so well with it five million years ago as early hominids.  And so therefore, all you have to do is adjust things to take into account the fact that you have a slightly different programming of your cells. We see people, you know, people all the time just doing exceedingly well with this gene. And again, you know, if they took someone with and without and took the food away, the person without the floor is going to die first before the one who who is with the gene, if you expose them to certain pathogens, the one with the gene is going to do better. So you have advantages and disadvantages. But overall, there's, you know, it's not that one is better in any way than the other. So what you can do is the program that we developed and I know very similar to what you are using, you want to make sure that you have a fasting period. And typically, you know, 14 to 16 hours, maybe you consider time restricted eating, if you are ApoE four positive, very helpful, make sure to heal your gut. You want to minimize your exposure to any sort of inflammogens. If your home is filled with molds, you know, get an army score or a hurts me to score. See where things stand.  And I think again, similar to what you suggest, it is a low carbohydrate, mildly ketotic, ketogenic, plant rich diet. And of course, we're well aware. And I congratulate you for the tremendous work on plant paradox.  Let you know, this is let's be fair. Again, duh, this is life, right? But you've done a great job with showing. So what is it about plants that's not always perfect? And so, you know, life is complicated. And when you've got to look at these neural networks, and you've got to look at the physiology. And as you indicated in your book, some people don't do well with specific plants like nightshades. Other people not so bad. And of course, that's similar to the gluten story. And it's similar to the dairy story. And it's similar to other things that people are sensitized to. So we're all a little different. And I notice again and again, I suspect you do as well. Certain, you know, people that do the best are the ones that are able to kind of go with the flow and say, okay, this is working better for me. This is working a little less for me. I'm going to keep evolving my own personal program. This is personalized precision medicine based on what's driving it. So there are a lot of things you can do to answer your question about ApoE4 starting with an appropriate fasting period, an appropriate food, exercise, critical, beautiful study a few years ago, showing that the magnitude of the effect of regular exercise on your risk for dementia was approximately equal to the magnitude of effect of one ApoE4 gene. So in fact, again, tremendous amount you can do. And then one of the things, Stephen, that we're finding that I was actually surprised by is that the very commonly people who are slipping into dementia have or a high risk for dementia have poor oxygenation at night when they're sleeping. They don't realize it. Their doctors don't check. They say, oh, I don't think I have sleep apnea. I don't snore a lot. Please, everybody check. It's turning out that you have got to support those 500 trillion plus synapses and critical to have the oxygenation. Of course, we're hearing about this with COVID-19. Everyone's checking their oxygenation. Great idea. Please get an oximeter or ask Dr. Gundry or your doctor to loan you one or get a sleep study. And if you're dropping into the low 90s or the high ages, we've had people as low as 71% while they're sleeping. Just unbelievable. And there was a beautiful study that came out about two years ago showing that if you just look at the average oxygen concentration while sleeping, that directly correlates with the volume metrics of multiple nuclei within your brain, including ones that are critical for Alzheimer's disease. So there's this beautiful correlation. If your oxygen is dropping at night, you are increasing your risk and your doctor's not checking it and you're not aware of it. And so it really allows this to sneak up on you. Critical thing to do. So, you know, that brings up a point. We used to have this wonderful test that was available from only one company looking at cardiac tropon in eye in pica grams per milliliter. Most of them are nanograms per milliliter. It was incredibly sensitive. A hundred times more sensitive. And we were using it to look for the subtlest signs of cardiac ischemia. But one of the interesting things we found was it was extremely sensitive for predicting sleep apnea. And yeah, so you're right. The heart was getting ischemic at night. And you couldn't see it on a regular blood test, but we could see it on the super sensitive test. And we'd get sleep studies on these folks. And sure enough, you're right. They may not have had a big history of snoring. They denied it. And some of these guys were the worst ones. And so when we got them on CPAP, or we got them to lose weight on my program, their cardiac tropon in eye normalized. And it was very fascinating. So you're right. Yeah. And you know, this is interesting to me because what you're seeing in the heart, we're seeing in the brain, you are getting these areas. You're just not functioning as well as you should. And I'd say, again, with this idea of you've got to support that brain, you know, it's running like a Maserati. You have really got to support it well. And the other thing that's come up is continuous glucose monitoring. As you know, this has been huge. Not only will people see spikes, which of course are very damaging and helping to give them insulin resistance. But also so many people who are waking up at 2 30 a.m. 3 a.m. 3 30 a.m. So I why am I waking up at night? Well, guess what? Your glucose is dropping to 40 or 45 or 50. You are getting hypoglycemic, also bad for your brain and heart and not realizing it until you got the CGM that showed you. Yes, you're getting this burst of adrenaline in the middle of the night, and it's harming you because you don't have a nice, smooth, high fat diet. You've actually got a too high carb diet and you're getting this reactive hypoglycemia. So these things, again, people don't look for them and they're so critical in our cognitive function. All right now, Dale, as the devil's advocate, somebody's listening to this saying, now, wait a minute, I know that the brain runs on glucose. And so the proper way to avoid Alzheimer's is a high carbohydrate diet. And there are a number of our colleagues, we will call them that, who clearly advocate for a low fat high carbohydrate diet for this very purpose. So what do you think? Yeah, well, I understand that they're trying to say, OK, this is about your vessels. Let's see if we can remove the lipids from your vessels. And unfortunately, as you know, this simply hasn't worked. And so there are multiple publications, you know, everything from Mediterranean diet, mind diet, the stuff that we've published. There's no question, getting into ketosis is critical for support.  OK, you can look at that directly by getting an FDG PET scan. When you get a PET scan, as you know, with someone even 10 years before their diagnosis of Alzheimer's, you see a loss of the ability to metabolize glucose in the temporal and parietal regions. It's a classic signature of Alzheimer's and pre Alzheimer's. So you really got your engine that's now sputtering. You cannot utilize this. So you really have an energy failure, an energy gap. And as you know, Steven Kinane has done very nice work on this and others. The way the best way to bridge that energy gap is with those ketones.  You want to make your own ketones. But for the short period, the first couple of months, just go on exogenous ketones. It's fine. Just just, you know, get rid of that gap.   And of course, that includes making the blood pump in there, doing the exercise, and includes getting the oxygenation and includes making sure that you don't go into significant hypoglycemia. All of these things are playing together just like an orchestra to give you the optimal ability, the optimal function. And by the way, as we mentioned in the book, this is also true for younger people who just want better function. People who are in there, you know, 20-somethings and 30-somethings and early 40-somethings, we used to think of Alzheimer's as a disease of the 60s, 70s and 80s. But guess what? The pathophysiology starts 20 years earlier. So Alzheimer's is really a disease of your 40s, 50s and 60s that gets diagnosed in your 60s, 70s, 80s. So that's a good segue. I've said to whoever would listen, if I had one blood test, the only one, to tell me my fate or my patient's fate, it would be a fasting insulin level. So what does insulin sensitivity have to do with all this? And you speak very eloquently in the book about this. Yeah, this is such a good point. And you know, Professor Ed Getzel from UCSF has published some beautiful studies using neural exosomes, literally taking these little lipid dots that you have, billions in your blood, taking these out and evaluating them because they actually come from the neurons in your brain, little pieces that are coming off of there. And showing that if you look at the insulin signaling, so as you know, the insulin binds to its receptor, the receptor signals largely through a molecule called IRS1. And that IRS1, when you have high insulin, because you've had a high-carb diet for years, your insulin is high. And then what happens is your IRS1 actually gets phosphorylated on specific serines and specific threonines that are basically like putting earmuffs on. So if you've got a son who's playing the drums 24 seven, you've got those earmuffs, okay.  And when we used to, you know, we used to grow neurons in the lab, you had to include insulin, transparent and selenium to get them to live. The insulin is a critical growth factor for neurons. Well now what you've done by eating all the carbs by ramping up your insulin, you have turned off your ability to respond to insulin. So that's the worst thing you can do. You've now got insulin resistance and now it doesn't give you that same sort of kick, either metabolically or trophically, that is so critical. And that's why this is such an important risk factor for Alzheimer's disease. Now you mentioned your program is called the KetoFlex 12-3. Right.  Yeah, so it's 12. 12 hours is the minimum fasting period. And again, if you're ApoE4 positive, you want to make that 14 to 16 hours. If you're ApoE4 negative 12 to 14 hours, good enough. Between finishing your dinner, starting your breakfast, brunch or lunch, it turns out to make a big difference. Of course, it helps with your autophagy. It helps with your ketosis. It helps with cleaning up your brain with the various things that you're developing, the damaged proteins and damaged lipids and carbohydrates, advanced glycation end products, all of these things. So that 12 hour fast is helpful.  And again, same reason. Because if you're not spiking your insulin while you're sleeping because you've just eaten, you're going to have a tendency to get a hypoglycemic episode in the middle of the night, wake you up and mess up your sleep, mess up your sleep stages, all of the above. So this is why we call it KetoFlex123. It's ketotic. It's flexitarian. You can have some fish and meat and things like that. If you want to, you don't have to. You can be, you know, vegetarian if you want. But you want to drive your bio chemistry toward the biochemistry that supports synaptic production and synaptic maintenance. And you want the 12 hours and the three hours to give you the best shot at improving. OK, so all right. And I thank you for mentioning in the book that certain lectins may be problematic. And I, of course, agree with you. But how do pathogens and toxins fit into this Alzheimer's equation? I mean, aren't the ApoE4s protected against these guys? Well, they have a more brisk inflammatory response to them. But this is a good point that you bring up. So again, we're, again, we're agnostic, whatever helps. And of course, as you pointed out in your work, for some people, they're very sensitive to lectins and they're not going to get rid of their arthritis or their other problems until they get rid of those. And so there are specific toxins and pathogens that are associated with cognitive decline. And in general, the pathogens tend to be chronic pathogens. So when you look in the brains of patients with Alzheimer's, what do you see? You see P. gingivalis, which comes from your oral, your dentition, right? And you can actually measure these things now very easily with an oral DNA test. This is the stuff that's giving you periodontitis. We'd like to see low levels of P. gingivalis, low levels of T. denticola, low levels of pre-vitella intermediate, low levels of fuzobacterium nucleotom. All of these things are pathogens. You want to have the good bacteria. So the oral microbiome is absolutely critical, just as the gut microbiome is for neuro degenerative diseases such as Alzheimer's and Parkinson's. You find those very bacteria in the brains of patients with Alzheimer's. You also find herpes simplex from your lip. And there's a beautiful study out of Taiwan showing that people who actually treated their outbreaks had a much lower, less than 50% of the likelihood of developing dementia as those who did treat them. So if you're treating them much better than not treating them as it turns out, and as you know, treating them is pretty simple. And then HHV6A, which appears to be coming in actually through the sinuses, and then various mold species that again come in typically through the sinuses. And then even Candida is found in Alzheimer's disease brains. So part of if you think about the amyloid, the amyloid that is produced in Alzheimer's is a response to insults. And it is actually a part of your innate immune system. So again, just like with COVID-19, cytokine storm bad, adaptive is what you need to get rid of this. Same thing in Alzheimer's. There is a gap between what's coming in in your innate response, which is chronically activated, which is what's giving you that amyloid, and the adaptive response, which should be clearing. And in fact, people with Alzheimer's have a increase in their innate response and a decrease in their adaptive. And that's one of the things to give you better phagocytosis, better antigen presentation. Omega 3s, vitamin D, some of the very things that help reduce your risk for Alzheimer's. No surprise. So this all fits together beautifully. And as you say, toxins and pathogens, the toxins come in three forms. It's metals and other inorganics. As you know, air pollution has turned out to be one of the important risk factors for Alzheimer's disease. So be careful when you're on the 405, right? And then secondly, organics, things like toluene and benzene and formaldehyde and glyphosate. So again, if you're out there burning paraffin candles all the time, please beware you're getting exposed to some toxins, switch over to some beeswax or something like that. And then third group is the biotoxins. So things like trichothesenes and ocarotoxin A and gliotoxin. Of course, these molds are just trying to survive.  Of course, that's where we get penicillin. They're trying to kill the bacteria and survive. And unfortunately, they make toxins that are very damaging to human brains, to human immune systems and to human kidneys and livers and can even increase your risk for cancer. So those are the big toxins. So you want to know if you've got exposure to pathogens or toxins and you want to direct your treatment toward those as part of the overall plan. Well, so how does someone go about finding out all of this about themselves? Yeah, great point. And unfortunately, as you know, at the Alzheimer's centers, they're not checking these things.  We're going to give you a drug. It doesn't work very well. You're going to continue to decline, which really makes no scientific sense. And so the idea is you need to know these various pathogens, toxins, et cetera. And so we set up something we called a cognoscopy. It's a silly word, a kind of corny, but it's it's easier for everyone to understand. We all know when we turn 50, what do we get? We get a colonoscopy. So hey, let's not forget about the brain. So if you're 45 or older, please everyone get a cognoscopy. And it just consists of three things, a series of blood and urine tests, looking at the very things you were talking about, things like fasting insulin, HSCRP, you want to know am I systemically inflamed and looking at things like vitamin D and omega three status and all of these things that are the players that determine whether you are going to get Alzheimer's or if you already have it, why you got it. So that's one second one, simple online cognitive assessment. You're going to do either mocha score, CNS vital signs, that sort of thing. You want to know where do we stand with respect to ongoing cognition takes about 30 minutes, very easy to do. And then if you're completely asymptomatic, you're done. You just need those two things. If you're symptomatic, you're going to also want an MRI with volumetrics. You want to know is my hippocampus beginning to atrophy.  So that's the third piece only necessary if you're symptomatic. When you have those three, we generate, we have an algorithm that's computer based and then we can generate something we call a recode report. It simply says, here are the things. Do you have mostly an inflammatory cause for cognitive changes or risk? Is this mostly a trophic? Is this mostly glycotoxic, vascular toxic? What have you? It'll tell you because as you know, it's different for each person. You want to know what are the things that I have to be concerned about so that I can avoid decline.  I mean, how do you find out about this? Great point. And the easiest thing is just to go on MyCognoscopy.com and you can actually get these directly. You can get the blood test and then you can take the report to your doctor and say, here I got my report. Here's where I stand. Can you help me with this? And we've got, we've trained as you know, over 1500 physicians from 10 different countries now and all over the US. So there are many people who are now doing this sort of thing.  Yeah. And, you know, in congratulations on doing that, I know that's been a labor of love for you to train thousands of healthcare providers now in your methods. So and it is, it's starting to appear. And I, you know, sent some patients who live in various parts of the United States. And sure enough, they have found physicians that you have trained. And so, you know, thank you for doing that. Thank you, Stephen. And we've got new training that's actually coming out next month in August. So recode 2.0 training. And we've got some fantastic things. Dr. Neil Nathan, who's really the world expert on biotoxins talks about his approach and Dr. Chris Shade, who's an expert in chemotoxins talks about his approach. So I'm really excited about that. All right. So we've talked kind of on this in preventing Alzheimer's and cognitive decline. What if you're, you know, you suspect you have it or someone has told you you have mild cognitive impairment or early Alzheimer's, same steps here? Or do we have to go even further? Very good point. And so, as you know, the earlier the easier and the earlier, the more complete, which is why we suggest to everybody, either come in for prevention or come in as early as possible. This idea of Leo, you hear it all the time from doctors, you're not that bad yet and there's nothing we can do anyway. So just come back next year. Terrible idea. You want to get going as early as possible. And yes, you're right. The farther along the more you've got to tweak this, the more you've got to look at all the different contributors and address them. However, the idea is the same.  You are restoring neuro plasticity. The later you wait, of course, the more you've lost and so the more you've got to restore that. But again, there is a lot to do. There are stem cell trials ongoing and I think stem cells are going to be an important part of the overall restoration. So you start by removing the problems that are actually causing this, seconds that you want to create resilience, optimize these various factors. And there's so many good things to do now along those things like, you know, whole coffee fruit extract, which helps to increase your BDNF. It helps you with, you know, your exercise, which is also increasing your BDNF and optimizing specific hormones for its specific times depending on whether your hormones are contributory. You can do all these things. And then ultimately, the third piece is regeneration. So you want to now bring back the synapses that have been lost. And this is where stem cells can potentially be so helpful. Some of the ongoing trials of stem cells are just as a monotherapy. This is very much like trying to rebuild a house as it's burning down. So yeah, great. You're throwing that next brick and every time you put anything in, it's now being, it's burning down again, you know, so you've got to get rid of the fire first, get rid of all the contributors. Now rebuilding makes a lot more sense. Now, that's a really good point. I have a number of patients who've had stem cells for arthritis in their knees. And a number of them have had some early benefits. And then six months a year later, they're back to square one because you're right, the underlying process was not treated. Absolutely. Yeah. So yeah, I think they're going to be a marvelous edge on what you got to stop all the other trouble first. And the same goes with drugs. As you know, people are now trying to say, well, take away you, let's take away the amyloid because things will be better if you just take away the amyloid. Well, no, you want to take away what caused the amyloid to be there. I know the thing that's been interesting to me, it's the same thing we're seeing with the reopening in COVID-19. You've got a problem in this case, the virus, and you're saying, okay, the protection from this is a downsizing. It's unfortunate. We've entered a recession because we are protecting ourselves from this virus. This is exactly what we see with amyloid. You are downsizing the brain to protect itself very much like we see it with COVID-19. So then you say, okay, now what we want to do is reopen everything. Everybody start going back. Just just ignore that there's a virus there. This is what happens when you remove the amyloid. You're removing both the downsizing, which is the good part, but you're also removing the protection. And we've seen a number of people now that when they had the drugs to remove the amyloid, they clearly tanked each time they had these administered. So please, remove the insult first, and then I think removing the amyloid is a great idea after you've removed the insult. That's a very important point and probably not recognized by a lot of our fellow practitioners out there, unfortunately. Yeah, important. All right, I've got to let you go. This is a great book not only for the end of Alzheimer's, but it is a one of the best disease preventing books that I've ever read and I was pleased to be able to read it beforehand and give you that blurb. And I mean that sincerely. So I don't care if you're worried about Alzheimer's or not. If you want a lifestyle book to protect yourself from chronic disease, I couldn't recommend this more thoroughly. So Dale, where do people find you? You've mentioned Cognoscopy and what else we got? Yeah, you can go on DrBredesen.com, mycognoscopy.com, on Facebook, DrDale Bredesen, any of those easy to find me and get more information. And please, everybody, stay safe from COVID-19 and let's make sure that we reduce the global burden of dementia. We absolutely can do that now. And Stephen, I know you're doing it every day. Thanks so much for the great work you're doing. Thanks so much for speaking up on lectins. I think this is really important. I think you've got as many arrows in your back as I've got in mind. And thanks so much for the discussion today. Always enjoy talking to you. Always pleasure to see you and write another book and we'll get you back again. All right, thanks, Stephen. All right, take care. All right, stay safe. All right, it's time for our audience question. And this is a perfect Paul S. on YouTube asked, if you have Alzheimer's symptoms and then determine that you have the apo-E4 gene can reducing saturated fats reverse symptoms? Or is it too late at this point? Well, that's a great question. And I think both Dr. Bredesen and I have talked a lot about this. What is happening at this point if in fact you have symptoms is exactly what he talks about. You've got to remove the underlying causes that have brought you to this point. And you've got to get in a position to start having insulin sensitivity. That is, having your brain be able to use ketones as an alternative energy source. And quite frankly, the only way to do that is to practice excuse me, time-restricted eating, which I spend a huge amount of time in the upcoming energy paradox, teaching you how to do that easily and safely. There is a point where saturated fats, particularly medium-chain triglycerides, have a good effect in getting you insulin sensitive. And I've talked about that in all my books, so I'll refer you there. But no, there's far more important things to do than removing saturated fats from your diet. We've got to retrain your cells to be responsive to insulin and retrain your mitochondria, how to use both sugar and free fatty acids, fats, as fuel, like switching from one to another. And about 80% of us have lost the ability, what's called metabolic flexibility, to burn fat as a fuel versus sugar as a fuel and do it instantaneously. And that's actually what the energy paradox is about. And the end of Alzheimer's program is a good starter for that as well. OK, now it's time for our review of the week. This week's review comes from Sabine Schultz, who wrote me an email after our recent episode with Dr. Lisa Mosconi. Dear Dr. Gundry, thank you so much for this podcast. I've been thinking about that topic so much, as my mother suffered from Alzheimer's disease and Parkinson's. And I'm understandably quite concerned about my own health. This podcast is really helpful for me. I always love hearing from you. So remember, you can rate and review us on Apple Podcasts or drop us a comment on YouTube. You can even sign up for our weekly podcast newsletter at drgundry.com. So I can't wait to hear from you soon. That's all and we'll see you next week. Before you go, I just wanted to remind you that you can find the show on iTunes, Google Play, Stitcher or wherever you get your podcasts. Because I'm Dr. Gundry and I'm always looking out for you.


You shoulda teared some of you with this thing. Now, keep your data usage below this thing.  No, well, no. We're actually, like I moved everything to business because the number of phones we have on this plan, a family plan doesn't hold it. So they had to upgrade us to a business plan. To a family business. Mm-hmm, man. You went with the enterprise plan because you have too many members. Yes, said Nabynese, Nabynese plan. Yeah, yeah, we can't, like on a family plan, I think the top, the top number of phones you can have is five. Uh-huh. I think we have seven. Geez. Now we have seven. I know.  You should incorporate your family. LLC. They already are. Corralta LLC. Well, it is. It's under my business, right? Yeah, yeah. Everyone pays into the health plan. And they are now. I mean, I hire them to do stuff every once in a while. So. There you go. How are you not to go for that? The bandwidth gap data cap. On the control when you get a chance. You got it. Contarole. You already have it. Oh, why is it not showing up on me? Dang you. Dang you in your slow bandwidth spectrum. Someone printing something? No, that was just my, every time the air conditioning goes off in my house, the surge protector goes. No. Yeah, I get that. I get a switch on my UPS. It doesn't go off, but it does the, you have a, we have a power sag. Mm-hmm. Yeah. Just clicks. Mm-hmm. Yeah. With little relays. At least I know what's working. Saggy power that leaks. Saggy power. So here there's a Botox can do wonders for that. All right, Dan, you ready? Let's rock it. Have we entertained you sufficiently? Sufficiently entertained. Good. All right. Here we go. Daily Tech News Show is powered by you. To find out more, head to DailyTechNewsShow.com slash support. This is the Daily Tech News for Friday, July 7th, 2017. I'm Tom Merritt joining me today, senior writer for Tech Republic. Dan Patterson in the house. Been too long, Dan. How you doing? Hello, world. Great to talk to you today, Tom. Absolutely. Dan just recently returned from Ukraine at a global cybersecurity summit where you had many adventures it sounds like. Yeah, we did. We learned a lot and talked very serious things about the state of global cybersecurity, but also ran a crazy James Bond movie for a week or so. No kidding. So we're gonna talk a little bit about what was discussed at the summit, but also some of the crazy James Bond things that happened, but let's start with a few tech things you should know about. Court has decided to let Uber depose Alphabet CEO Larry Page as part of that Waymo Uber lawsuit. Waymo pulled three of their patents out of the case, but they still have one in it. And frankly, the main case is about trade secrets anyway. Uber plans to ask Larry Page about why Alphabet shows not to partner with Uber on self-driving. It's not just sour grapes, but Dan, it's probably them trying to show that Alphabet didn't think that Uber was doing something similar to what they were doing. Yeah, we'll see. It's one of those cases where the facts really are going to matter and these two companies, regardless as to what happens with this case, these two companies are on a collision course. So this is kind of the vanguard of news to come. Samsung projects its highest operating profit ever will come in Q2 at 14 trillion won, up 72% year over year. It's $12.11 billion US. Samsung hasn't provided all the details yet, but the analysts looking over everything say it's probably strong sales of the Samsung Galaxy S8 as well as strong sales of chips like RAM, processors and some display components have been selling well for Samsung. It looking very rosy for Samsung right now. Explosive growth. It shows you how short the news cycle is, right? A year ago, we were talking about this is the death of Samsung. How will they ever recover? They did just fine. Yeah, and I remember trying to deflect people saying like, how is this gonna hurt Samsung? And saying, look guys, it's a PR nightmare for them. Maybe it kills the note, although it looks like that's not even the case. They're gonna come out with a new note this fall if everything pans out the way the rumors are going. But remember Samsung does a lot besides phones. So I knew Samsung would do okay. And it looks like they did the right thing with the Samsung Galaxy S8 in getting people to understand, hey, this phone will not explode on you. And the S8 is just a really good phone. It is. The Verge verified a report by the information that Jawbone has entered into liquidation proceeding. So no more Jawbone or is it Jawbone co-founder and CEO Hussain Rahman reportedly started a new company called Jawbone Health Hub, which will focus on health related services and provide support for legacy Jawbone devices. So there's a little bit of a shell game going on here, Dan. Yeah, you know, there's massive growth in the industrial internet of things. In consumer IoT like Jawbone, it's a real heated space right now. And it's nice to see a pivot to help. We'll see if that Jawbone brand can carry in any weight or if they're gonna get trampled by the giants. This is one of those stories that people only read the headline and say, oh, Jawbone going out of business. Well, too bad, goodbye Jawbone. And then a year from now, they see some Jawbone health services things and go, didn't I read that Jawbone went out of business? I'm not gonna believe anything I see in the news anymore. And the fact is, yes, this Jawbone as we know it is going under, but it is like you said, it's a pivot where they're saying, look, this enterprise is not working anymore. We're winding it down, selling what assets are worth something to ourselves in this enterprise that we can get going and start fresh with. Smart move. Yeah. Comma.ai launched a toolkit Friday to help car owners access the data from sensors in their car. Toolkit consists of a few different parts. There's a hardware dongle called Panda. You plug that into your OBD2 port and it works with software called Cabana to read out the data. Not just the publicly available data you normally get from the OBD2, but with George Hott's computer magic, he's able to read a lot of the same stuff that the factory could see. It will then store that data in something called the OpenDBC, the Open Database for cars where you can all help each other. Other car owners that have this dongle can look at each other's data and help interpret it. So once it's interpreted for one car, it'll be easy for everybody else that has that same model to interpret it. Comma.ai founder George Hott believes it's the first step toward making any car autonomous. This is his step back from a $1,000 kit that he was going to sell to turn any car into an autonomous car. He ran into regulatory issues. So he has stepped it down quite a bit to this $88 kit that just helps you build the data that you need. That is expected to start shipping in four weeks. It's, you know, everybody's kind of sick of hearing about machine learning this and AI that, but this is really in big data. But this is where the marriage of machine learning and big data is really going to create some practical outcomes. Whether this particular manifestation exists in a year or so we'll see, but really this is where data and machine learning shines. I'm seeing more and more efforts to become the android of car services. So we've seen that from Baidu and George Hott says exactly the same thing. He's like, I just want to make a platform that anybody can build on. He would then stay away from the regulatory issues of having to create car parts and just create a platform that people could build upon with their own car parts. And I don't, like you say, I don't know if this becomes the android of self-driving cars or if it's Baidu or somebody else, but it does seem like we are going to get a few platforms out of this open and proprietary both, just like we normally do with new platforms. This is a signal of the future. Whether it's this company or this platform, who knows, but this is where the future is going. Remember, do you remember when Elon Musk got on Twitter and told the Australian billionaire, I can build you a battery storage for your power grid in a hundred days? I do know. Yeah. Tesla has agreed it's official to build the world's largest lithium ion battery storage facility at Australia's Hornsdale Wind Farm by December 1st or it's free. Tesla Power Packs will have 100 megawatts, 129 megawatt per hour capacity, and they hope to power a maximum of 30,000 homes. Of course, the reason for all of this is South Australia's power grid has suffered frequent outages because of storms and a lack of capacity. So this would allow them to use, among other things, solar energy and store backup power to get them through those outages. Tesla has built a smaller facility like this on Kauai, the Hawaiian Island. So they have a little experience at this point and this will still be their biggest project, though. More of this, please. Anything that pushes power and efficiency of energy storage forward is a good thing. Yeah, and I want it to succeed so that Tesla can do it elsewhere and other people start saying, well, hey, wait a minute, if he could do that, we could do that, too. Yeah. New York Times reports that according to a joint report of the U.S. Department of Homeland Security and the FBI, attackers have been targeting the networks of companies operating U.S. nuclear power plants for the past two months. The Wolf Creek Nuclear Operating Corporation is the only target named in the report, but there's around a dozen that aren't named. It's unclear if the attacks are meant to steal information or disrupt operations. However, attacks have been successful in infiltrating individual computers. They have not reached operations systems or control systems, which are kept separate. Thank goodness. Not yet that we know of. Not yet that we know of. Those are very important words. And hopefully they are kept as separate as this report would like us to believe. This is sadly not an uncommon story. This is not a surprising story these days, is it? We'll be bored to death and sick to death of stories like this soon. This isn't the far off future. This is the right now. And whether the public or consumers care, whether companies care, these types of cyber attacks that target critical infrastructure are going to present not just tactical challenges, but real existential threats when it targets nuclear facilities. And when we couple that with propaganda that's happening, I mean, everybody's tired of the fake news discussion, but social media helps spread this information which keeps the public from focusing on stories that actually do have critical importance like this. Yeah, it's the time where we find out if those scare stories about SCADA systems that had the passwords of one, two, three, four and the like were just scare stories and that these companies have locked those systems down better or if we need something bad to happen before everybody really gets in gear and protects these incredibly important and dangerous systems. Yeah, something bad is going to happen. What we saw happen in Ukraine with the shutdown of the power grid was hackers were able to overwrite the serial to ethernet cables and destroy, eliminate the firmware which prevented defense mechanisms from going into shutting down the attack. When we see something like that happen, we'll see other types of attacks happen here in the West and those type of attacks, sadly, there may have to be some sort of critical event happen, but those type of attacks really indicate a sophistication and an intent to do harm. Well, we're going to talk a little bit more about what's going on in Ukraine and global cybersecurity. So let's wrap this up. If you get all the tech headlines you want each day in about five minutes, you're listening to DailyTechHeadlines.com. That's what we do in our sister show. All the tech headlines quick and efficient for you as a podcast, as an Amazon Echo flash briefing or on the anchor app at anchor.fm that's DailyTechHeadlines, DailyTechHeadlines.com. So the Global Cyber Security Summit in Kiev, Ukraine was very interesting. You got to interview former U.S. Deputy Secretary of State Anthony Blinken about the need for cyber defense. On the one hand, this is governments and officials coming together trying to plan out a strategy, but on the other hand, Dan, it sounds like a lot of the speakers at this conference were saying, we really need governments and NGOs to come together and plan out a strategy. Yeah, so there are a number of cybersecurity conferences as everybody knows around the world, including Black Hat, RSA. This one brought together specifically folks in the government and public space, NGOs and private companies. And that message that you just said, it was exactly right. Everyone agrees that there needs to be public-private partnerships, but those are really hard to do when you have competing interests and you have, for the most part, a cybersecurity community of people who, I mean, let's be honest, we still use the word cyber security. This is an insular community that tends to talk to each other and they don't do a great job of talking to the public. Some of the people who do are like Greg Michaelides from the New America Foundation and others who really do a good job of using not the jargon and instead using common words and common language, but really a fantastic shot. This is an opportunity for a lot of people to talk to each other and kind of step out of the bubble. Excellent. Yeah, so if you're watching the video, you saw that my dog just knocked over the camera because someone was here with mail. We'll fix that in a minute, but you keep talking. I think what's interesting about this to me in a way is that Ukraine, I'm guessing, you didn't have a lot of representatives of Russia attending this Global Cybersecurity Conference. Oh no, no, in fact, we were, I mean, if ever the really interesting thing about these times is that in the age of terrorism, for the last decade and a half or so, you have kind of this amorphous and difficult, it's difficult to point to who the threat actor is and that's very similar to what we have in the hacking age. One difference though is the presence of Russia in terms of a financial underwriter of different types of attacks. Russia really, so Russia behaves in a way that they want to disrupt many of the systems in the West and they target not just IoT systems and computer networks and mobile networks, but they also use propaganda to dissuade people of real facts. One of the things that Blinken said was that we really need to have an emphasis on public-private partnerships. We need to set international norms and standards and we need to work on deterrence. Those three things will kind of slow down what we see in terms of targeted attacks against the West, but we won't ever, we won't get rid of the Russian threat and it's very strange to say this one actor underwrites a lot of the activity around the rest of the world or at least is a spark for a lot of the activity around the world. There aren't, I mean there are anonymous groups of hackers, but we can in this instance point to a group and say this is what they're doing. For example, Russia is fighting a kinetic war in the South in Crimea, but they're also targeting the infrastructure, the power systems in Ukraine. And what that causes is Ukrainians to write ransomware that then attacks the rest of the world so that they can fund the resistance against Russia. So if your company was hit by a ransomware attack, it's likely that this was to help raise money so that Ukraine can fight back. Russia also funds a lot of the organized crime groups in Eastern Europe and they also fund university students to study cybersecurity and study hacking. So it's a real asynchronous attack that's happening against Ukraine and then that's spreading out to the rest of the world. And of course, I mean, you're getting one side of this when you're in Ukraine because you're not getting Russian representatives and I'm sure there is another side of the story that Russia would like to tell about this. But the fact of the matter is, Russia is doing a lot of the things that you're saying and the United States is out there doing cybersecurity attacks on other nations.  North Korea obviously has been suspected of doing cybersecurity attacks. The point of the matter I think isn't so much to point it at Russia or China or the US in particular, but to say, hey, wait a minute, we've got the Wild West right now and all you're gonna do is escalate it if you say, well, that country is doing all of this stuff. So now we have to do stuff too. I think one of the best messages that I heard coming out of the conference that you went to was, we all need to agree on these standards of practice, these norms and standards so that we as governments, we're not even talking about terrorist agencies or anarchist collectives or the ones who won't participate in this. Governments should be talking to each other saying, hey, we should all be fighting against the criminals, shouldn't we? Let's figure out some ways to deal with this. And part of that is to reduce the incentives. So if you reduce the financial component, then you can in theory reduce the threat actors and the various agents. And you're right, it is not just Russia behaving in a manner that find threatening, everyone is doing this. And this is an existential challenge because if there are vulnerabilities, there are agents who will exploit those vulnerabilities. And because we have critical infrastructure that civilians rely on, we have to treat every vulnerability as though it is high risk vulnerability. And it's hard to tell the state actors from the state supported actors from the independent actors as you sort of found out in practice just getting off the plane in Ukraine. Yeah, it's what's very interesting. So to share a couple of stories, we were initially hit with a stingray by Stropel Airport, the international airport in Kyiv, has been the target of cyber attacks since December, 2015. And there certainly are stingrays there. You can tell, we've written a few stories in tech republic about how the tactics are used, but you can tell if your phone tries to connect to a network and it just spins and spins and spins without providing any data. We were also- That used to be called Verizon and Marina del Rey, but that could also mean a stingray, yeah. And AT&T in New York City. Yeah, right, right. Right. So the other attacks we saw, and I think that probably your listeners are most likely to experience brute force attacks. And one of the things that you can do to make yourself more secure right now is to change your passwords and use a password manager like LastPass. You don't have to use LastPass, but it's a secure embedded application. One password is great too. Enable two-factor authentication on every site that offers it. And let's be honest, every site should offer two-factor authentication. When I took the stage to do a panel moderation at GCS, literally the moment I took the stage, my phone buzzed and didn't stop buzzing with emails that came in from different social networks saying, hi, we're Facebook. We noticed a login attempt from this IP address from every single account. Those were coupled with phishing attempts that looked almost exactly like, say, an audible email, but it came in from an audiobooks.com. One of the things that you can do that's real practical is to A, never click on links that come to your email, but B, double-check those domains. Often you see a domain attack where a typical misspelled domain. Also check the JavaScript that the redirect in hover over the link in an email and double-check that that redirect is actually going to the domain that it says and not forwarding you to some strange place. Often you don't have to enter your credentials. You can simply click on a JavaScript link and it'll pull in from your key chain, all kinds of information. So it's strange to take the stage and then immediately get hammered in profile as though we're coloring, we don't know what you look like, but we're gonna color in the lines around you. When that starts happening, you realize, okay, these attackers are real and they do want to at least send a message. And that is the James Bond stuff you're talking about, unless you were also chased through the streets of KL. Oh, we were, yeah, we were followed. Yeah, we were followed by, each day the attack stepped up. So a colleague of mine had, after room service came in, he had half, nobody's drinking glasses of water, he had a half full glass of water placed right next to a bed with a note that said, privet hello in Russian. And as soon as I heard that, I asked a room for, when was the last time? You know, I've been in and out all day, I forgot when was the last time I was here and I knew I'd not been there all day. And they said, well, 1235. All right, that's the last time. All right, definitely somebody has swiped into my room, let's change rooms. By the third day, I would sit and have a bottle of water in a courtyard, which was right next to the FSB, it's a Russian secret service. And these two goons sat like satellites on either side of me, one in a crisp white shirt, the other with tattoos and he was a big burly dude. And they, I mean, they make themselves known, they stare right at you and then followed us as we walked. And then we did the James Bond thing and kind of made weird corners and they're still following us. And it's just to send a message, but that's one thing that the Russians in particular are very good at doing, make you feel as though, I didn't know it was in a rabbit hole and I'm not sure where this ends. In fact, the final day we were there it was at the central bank conducting interviews and on the way home, we had strange emails show up in our accounts that simply warned that maybe we should back off a little bit and be quiet. I think one of the emails said, just change this topic of conversation. So. Yeah, and you know, that's the kind of intimidation that is meant to keep you from possibly inflaming passions around particular issues which Ukraine and Russia are fighting a border war by proxy in the West or yeah, I'm sorry in the East part of Ukraine as well as the dispute over Crimea which Russia now has under its control. So that doesn't surprise me that people are putting the pressure on you but it doesn't help the problem of look you guys need to talk to everyone else as much as we need to talk to you. And that's the climate that needs to be changed if we're gonna make it safer for everybody on the internet. Yeah, that's exactly right that there needs to be bilateral conversations. Yeah. Well, I'm glad you made at home safe. I'm glad you had a good experience at least, you know, informationally and would you go back again? I would. There are some other things that happened there. I would under some certain conditions. The people of Ukraine are fantastic. Yeah, absolutely. Well, thanks to everybody who participates in our subreddit, you can submit stories and build on them at dailytechnewshow.reddit.com not only stories, but you can submit guest ideas all kinds of things. People are in there chatting about the different stories as well. So go check that out. Got a couple of messages of the day regarding our discussion yesterday about Amazon and Dish having conversations about partnering up. Now, the sources that the Wall Street Journal and others have talked to say that Dish it wants to have Amazon fund the rollout of a wireless network because Dish has a bunch of spectrum and that Amazon has talked about some kind of connection with internet of things and Amazon Prime. That got us thinking along the consumer end, but anonymous person, although an Amazonian I don't have special knowledge of relevant products. I'm just guessing based on my understanding of how the company values and thinks, but he or she actually don't know which way it is is not representing the company anyway. This anonymous person says Amazon may make more internet of things devices, but I really don't think that's the main play. Interesting scale comes from being a platform for others. I think we want the things to succeed in an internet environment that includes Amazon web services so we can sell cloud resources to those who manage the things. Relevant IoT connectivity through Dish would be a compelling part of such an AWS solution. I'm sure we'll also happily run the shop where you buy the IoT services and hook them up. I think our sales assistants and facilities managers may already be in your house. But yeah, tying in IoT as a service to Amazon web services makes perfect sense. And then from our YouTube channel, Brandon added, Dish also does on-demand sell repair. They have sell parts in their trucks now, and I don't know if you've noticed, but Amazon services also offers on-demand sell repair. So maybe there's a partnership there as well. Dan, what do you think of these ideas? I think that's, I bet cash money, that's the direction Amazon goes. Making IoT devices is a lot less lucrative than making the networks that those IoT devices run on. Well, and now that I'm thinking about it, our theory had been, they'll sell more Amazon Echo-like devices for your home, for your smart home, maybe some doorknobs, et cetera, cameras, which they now have, right? In the Amazon Echo Show and the Amazon Echo Look, they both have cameras.  Well, yes. And they could probably provide serious backend, even if they do that for other enterprise services, other Internet of Things providers, and allow them to tap into that same network alongside of the Amazon Internet of Things devices. So yeah, I think our anonymous Amazon employee here is perfectly right. This would fit well into the AWS model. They probably would be considering all of those, don't you think? I think Amazon makes, I think that they want to make a lot of money from the scale here. So yeah, that makes a lot of sense. And as Microsoft and Google are chasing them in the enterprise web service and big data service, Internet of Things is kind of the next big field of play that Amazon wants to go put a stake in the ground first and maintain their leadership position. All right, well, let's check in with Len Peralta, who has been illustrating this episode and is very excited about Spider-Man Homecoming coming out this week. What do you got for us, Len? Yeah, I tried to shoehorn this into the idea. I mean, the discussion was incredibly fascinating. But I've got Spider-Man on the brain here. So I did take something here. This is actually an informative piece of art here. There's three components you mentioned on the show, but there are really four components for cyber defense on a global scale. One, of course, private public partnerships, international standards, deterrence. And number four would be, of course, Spider-Man. Oh yeah, Spider-Man is like, yeah. He's like, and Spider-Man's saying, oh geez, I wrote this. That's like totally untrue. And really, Tom's dog might be the best defense, though. You got to be on the right there. Tweet that to Blinken, he'll love it. Yeah. I think Ray may have been acting as an agent of a foreign power when she, when... Right. That's quite possible. Actually, it was Sawyer who knocked down the camera on Ray, but still, for purposes of... Yeah, yeah. But she made it in there. So, or he made it in there, I should say. Is Ray a boy or a girl? Ray is a girl, yeah. She made it in there. Like Ray from... Yes, there you go. So yeah, so this is available right now at my online store, lennparaltstore.com. You can also become one of my Patreons at patreon.com.ford slash Len. And back me at the DTNS Lover level and you get each one of these things that I draw every week as a digital download. So go ahead and do that. That'll be awesome. Thank you. So, wait a minute. Dan, so this has Ukrainian hackers, Spider-Man and my dog. It's perfect, right? I mean... Yeah. This is the future of cyber defense. Yes. I feel safer now. Thanks, dude. With Spider-Man, I do. Yeah, for sure, man. All right, once again, lennparaltastore.com. If you want to just look at it, and of course, you can order a digital or a physical print while you're there. Thank you again, Dan Patterson, for joining us. Where should folks go if they want to find more of what you're doing these days? Hey, thank you guys. You know, my Twitter at Dan Patterson is probably the easiest. We have a long tech republic URL, but I have the most recent story about hacking in Ukraine at the top of my Twitter at Dan Patterson. Go follow him now. Thanks to everybody who gives a little value back to this show for the value they get from the show, including Leonidas Vraknis, Ben Love, Chris Hunter, and many, many, many more. We thank each and every one of you for making this show possible. Our goal every month is to just have one more patron than we had last month. So if you've been thinking about joining, now's a good time. Patreon.com slash DTNS. Our email address is feedbackdailytechnewshow.com. We're live Monday through Friday, 4.30 p.m. Eastern, 2030 UTC at alphageekradio.com and diamondclub.tv. We're at facebook.com slash dailytechnewshow. And our website is dailytechnewshow.com. Back on Monday with Veronica Belmont. Talk to you then. Show is part of the Frog Pants Network. Get more at frogpants.com. Bob hopes you have enjoyed this brover. We did it, even with my camera going down. So Sawyer has a hurt paw, so he has the cone on, which is I think why he would knock the camera down because he was running to the door and didn't judge the distance properly. What kind of dog is he? He's a border collie mix. Interesting. Yeah. Awesome. Maybe not gonna be down here during the show until the cone comes off. Excellent. Well, thank you guys very much. I really appreciate it. Oh yeah, no, thank you, Dan. I appreciate you sharing the stories with us. Oh, anytime. And braving going to Ukraine to get the story in the first place. Ukraine is fantastic. We had some, I almost didn't make it out of the country. At the airport. There's a couple of stories that just are better, like not shared publicly at the airport. We had... Well, we're still live, so just be, you know. Yeah, yeah, definitely. We'll see, the next one will be fantastic. There's AK-47s and crazy hackers. You know, the AK-47 just had its anniversary of it going on sale for the first time. It did. It's like, you know, the most popular brands in the world are like AK-47 and Samsung. Those things you see everywhere. Yeah. Two great tastes. Two great tastes. They go well together. Awesome. Thanks guys, I do appreciate it and we'll talk to you soon. All right, thanks, Dan. Take care, bye. See you guys. So, Roger, what do we got for titles? Samsung's exploding sales. Yeah, exploding sales. Blame the dog. This episode was filmed in front of a live studio animal. Samsung with dollar signs replacing the S. Jawbone is dead. Long whip Jawbone. Dan's got a bad feeling about this. Wopper of a fishing tail. Get it, Wopper? That's the computer that controls the SDVMs in war games. Dan speaks in Kiev. Kiev goes fishing. I like that one. So without their hacking occurs with a Russian Ukraine on my parade. I like that one. I'm going to click on that just because I think it's funny. The insecurity of cybersecurity. Cyber attacks going nuclear. Was that one the insecurity of cybersecurity? That one's good. Yeah, the insecurity of cybersecurity. I like that one. Well, keep going, but I kind of like that one. Powered six months or it's free. Something's going to happen and they'll probably have to pay. Take some of it in. Digital meltdown, nuclear hacking. Cyber attacks going nuclear. Nuclear, nuclear, nuclear, nuclear energy. Samsung and the AK-47. Newt Jell-O says one has killed millions and the other is the AK-47. Then he says, sorry. Samsung hasn't killed millions. Maybe under a million. Probably not. Yeah, it's a conglomerate. Many of its various arms may have been out of it. Yes, it's pronounced nuclear. Nuclear, nuclear, nuclear, nuclear, nuclear. Nuclear. Nuclear. Nuclear. So I actually didn't see Sawyer knocked. I was like, I thought the dog was on Dan's side. Dan touched us. Oh, really? Yeah, cause I was drawn and then I heard the dog and I'm like, oh man. And then all of a sudden I look up in your sideways. Yeah. Somebody dropped a package off at the door and he went running over to the door to defend me. Days like that, it's like, you just want to like toss him out the window. Was it this week or late last week when my LEDs fell off in the middle of the show? One of those weeks, summertime. I've done that. This week is a weird week. I think it's because of the 4th of July holiday. In fact, my parents were here. Yeah, it's been a really weird week. We had guests all this week and so it feels like I was sort of on vacation but not really because I was still upstairs working. Yeah, look, I'm sorry for yawning, yonzer. It's not the company, it's the hour. It's the company and the hour. It's the company hour. The insecurity of cybersecurity is my vote. Yeah, I'm with you. Let's use that. Well done, KV. Done. Exportin'. Done, exportin'. At least I have a long enough cable that I can walk over there and still hear. That's my internet still crappy. Dang it, Spectrum. I pay you your introductory rate for a reason. Oh, so we have a home line. I don't even know why we have it anymore. I've been meaning to try to get rid of it because all we get is just junk on there. No one ever calls us. They always just call our cell phone or they text us or whatever. So what I've been doing is I've actually been answering every call that comes in and doing a voice that says, hello, this call is being answered by a robot. And I just keep saying that over and over and over again until they hang up. Hello. You know, you do what you gotta do, right? It's fun. I'm like, oh, the phone, because it used to be like all the phone rings. Now you get excited. Now I get excited. Oh, I get, I'm gonna do this.  What do I do? I normally just, I used to just answer the phone and say, yup, and then people who knew me would know what to say. And people who didn't wouldn't. And I said, all right. Do it this way next time, Rhett. Rhett, try this one. So say, hello. And as soon as they start talking, the call you're trying to complete cannot be completed as dialed. Please hang up and dial again or ask the operator for assistance. Yeah, I wanted to come up with a really good script, you know. No, the thing is you wanna make it, your call cannot be completed as dialed. Hello, your call cannot be completed as dialed. But the pause, you pause. Hello, and then as soon as they start talking, your call cannot be completed as dialed. I'll do that one. Hello, your call cannot be completed as dialed. Please hang up and try the number again. No, just hang up. It's great. But I don't know if that will deter them, you know. What if they call back? They'll just keep calling back. That's okay. And then just do it again. Hello. No, no, you should have like, scripts are completely different.  Another one, you're like, you know, like you're just different people. Yeah, yeah, my brother-in-law, when he answers the phone, he says, hello, Sajja Maloney from the fraud department. And they just don't know what to do. Just start saying, thank you for calling. Your call is very important to us. Please hang on. And the next available operator will take. Did you read about that story about that guy who had this, he wrote a script to call back these scammers? Yeah. He made it call them back 28 times a second. Oh, yeah, I did hear about that. So it jammed their line so they couldn't make any calls out. That was great fun. Thank you for calling Len Peralta. Your call is very important to us. Please hang on the line. And the next Len Peralta will help you in the order in which your call was received. The next Len Peralta will call you. If you still had a voice fax modem, you could just plug your landlines to that and then set up your computer. Oh, yeah, there you go. And then just do what Kramer did on Seinfeld. Welcome to Moviefone. Please state the name of the movie you would like to see. Why don't you just tell me the name of the movie you want to see. Please press one for Len Peralta. Gladiator is also playing it. I bought tickets through Moviefone back in the day. Felt like living in the future. And it's so funny now that we would never call something to buy a ticket. Well, didn't Moviefone just become Fandango? I mean, that's all it became, right? Well, AOL bought it. So I don't think it became Fandango directly. But yeah, Fandango pretty much replaced it. Yeah, Fandango was the thing. Full disclosure, my wife works for Fandango. Yeah. Fandango is way better than it ever was. Full disclosure, this is my opinion. I love, I love Fandango. Yeah. I love Fandango's health plan. You're like that. And the paycheck my wife gets from them. You ever see that Twilight Zone where the, where that Billy Mummy like wishes people in the cornfield? He's like, it's called It's a Good Life. I love Fandango. That's real good. Right, Fandango's real good. Biocass says he got a sales call once and just started talking over them every time they started talking and then blamed it on delay. I remember, you could try answering the phone and then just pretend to break up. Hi. I can't just answer. Yeah, yeah. That brought the, I love. Interesting. Oh, I think I would, yeah. Reception. Oh, okay. Yeah. Really, all you need to do is just play the jerky boys over the phone. See, okay. All of these are funny until you realize that the person you're torturing with this is like a minimum wage employee who doesn't want to be there. Unless, unless you get those calls. See, every once in a while you get that jackpot call from Microsoft. We want to fix your. Oh yeah. Now if it's the fraudsters then they'll hold to Bard. Hello, this is Microsoft. I have found a virus on your computer. I told you about that. They called the other day and I was so excited. And I picked up by it because it came through with no caller ID and I was actually expecting a call from a client who has no caller ID. So I picked it up. Just thinking, yeah. And it was, hello, I'm calling from Microsoft. I'm like, oh, it is on. So, so, so all I did, I just kept calling, I just kept talking like I didn't speak English. Like I was just like, hey, okay. And I kept saying yes to everything. Yes. It's the wrath of Tagalog. They're just like, so, did you, is this okay? Can we, can we work with you now? Okay. What do you see on your computer? Puppets. And I just kept saying puppets over and over again. He's like, what are you seeing? Puppets. Yeah. Puppets. What were they trying to get you to do?  They wanted me to go to my, they said there was a virus on my computer that is causing my computer to slow down. And they needed me, they needed to take over there. They were calling from Microsoft and they needed to take care of my computer. So they needed me to go to a website, type in a URL and then, then from that URL, they would be able to gain control of the computer. Yeah. My dad just calls me and I take over control of his computer. That's like Christmas day when you get one of those calls because. Puppets. I love that. Puppets. Yeah. I was. Did you say puppets? Yeah. Because I own a home. I get a lot of the, I get all of the telemarketers who want to sell me solar panels. Oh yeah. Tell me all the advantages. It's like, I know. It's like, oh really? It's like, so, so would you be considering investing? It's like I could be. And then at the very end, I just tell them I'm renting. It's like, oh. Oh yeah. I mean, it's not a lie because I am renting, but I go to that right away when I see people like that. I'm just like, oh yeah, I'm rent. Oh, nevermind. Bye. Occasionally they'll be like, how do we get in touch with the odor? I'm like, I don't know. I don't know. He lives on the boat. I just have an address. I have a PO box to send my rent to. I wrapped my check around the pigeon's leg. He's somewhere in the Caribbean. I was supposed to be paying for this? What? I just like, I just walked in here. I'm just squatting. I'm squatting here. Oh man. Yeah, I think the guy that had the scammers that were calling that one guy, I've gotten those before. They'll say that there is a judgment against you and the cops are coming to arrest you. And so he was like, this is wrong. Like, you know what I mean? Like they're basically going after people who don't understand what's happening. And so catch them in a vulnerable position. Right. So yeah, for sure, man. I love the fact that he kept, called them 28 times a second. That's awesome. Jam their phone lines. Man. Be a douche, die by oh, I shouldn't say that. See, Roger, you've got to think about what you're reading. This is the lesson of fake news right there. I'm not reading. Are you reading JollyRogerTelco.com? No. I'm just reading stuff. I'm just reading Newsarama and a couple of the things. There you go. T, told you. Newsarama. What's Newsarama? I was thinking about something else. It's another Arama, but it's not Newsarama. All Arama? No, I don't know how I can't remember what it was now. It was sort of like, it was sort of like a low, like a, I want to say a low rent Boing Boing, but it was like a, it was like Boing Boing. It was just a compendium of links. It was Boing Arama. It's called Booboo. Boing Boing. It was something Arama, I don't forget what it was. It's just called Boing, because they can only afford the one Boing. It was a fun sight though. I don't remember who it was now. Boy. Man, you know what? I haven't actually looked in my bookmarks in forever. Oh, yeah. And these are, I have a delicious folder. Delicious. There's only one thing in it though. That's sad. So these aren't up to date. I have identica.ca still in my bookmarks for some reason. All right. Hey, did you send me, Tom, did you send me something from Peach the other day? Maybe, I may have, yeah. It was a while back. Like maybe a couple weeks ago. Yeah, it was a couple weeks ago. Yeah, yeah, I did.  Like what the hell is Tom Peach for? I was going through my phone, getting rid of apps that I don't use anymore. And I saw Peach, so I'm like, hey, that'd be still in there. So I opened it, I'm like, is it even work? So I opened it up. And of course, you were at the top of the list. It was like the most recent activity was like, Len shared a thing. And it was like, you know, 110 days ago or whatever. Yeah, 370 days ago. And so I was like, oh, I must wave back to Len. I don't want to leave him hanging for more than a couple of years. Right, so I went back. I'm like, oh, I don't even know how to do that. I'm like, you hasn't even logged in for like a year. I'm like, how am I gonna wave to him? He hasn't even logged in. So then I thought, well, maybe someone's, maybe let someone hack my Peach account or something. That happens a lot. You hear that a lot of people having their Peach hacked. Oh, the Peach hacks. They're the worst. Peach hacks. Yeah, remember that? That's hashtag Peach hack. So I went to my Yahoo to see if my bookmarks were still synced and they're not anymore. I was gonna look through my old bookmarks. I guess I'd have to pull up Firefox then. I have my old bookmarks. Cause apparently the bookmarks didn't, sir, didn't, bio cow, bio cow just sent me a yo but yo was one of the apps I deleted when I was cleaning up my phone. I'll never get it. That's so sad. I'm gonna have to go and install yo so I can get your yo by okay. Yeah, I thought I had synced all my old Firefox bookmarks. Oh, there they are. Right? What is this? It's Lenny calls? What is that? Don't know what that is. Royalty free music for YouTube. Arena Paladin tier lists for Black Rock Mountain. Well, that's old. And recipes. Recipes. Yeah. Well, the recipes I actually use all the time. I keep recipes in Chrome bookmarks so I can get to them from my phone. All right. Well, thank you all for spending time with us today. I hope you have a lovely weekend. Yeah.


Hey guys, welcome back to The Novi Show, it's your host International Nova and in today's episode we got some cool music news, a freedom partner spotlight and some beat music label updates. So let's get right to it. Now some of you guys know Beat is our music label here at Freedom and we are happy to announce that we have a brand new logo for Beat. Now you guys can head over to our official YouTube channel youtube.com forward slash Beat and check it out. We have the brand new logo, a brand new banner and very soon we'll also be having original content on the channel. We have also updated our Facebook page and our Twitter page to now have the new Beat logo and banners. We've also launched a brand new SoundCloud page which you guys can go ahead and follow at SoundCloud.com forward slash Beat MCM. Some of the other cool features we're working on is Beat Radio which will be a 24x7 online radio station that we'll be using to promote our beat artists and music as well as a brand new artist dashboard for our partners and artists. Now if you guys want some more information on the Beat label please leave a comment below, subscribe to our official YouTube channel as well as Twitter and Facebook the links are below. Now we're also looking for new partners to partner into our Beat MCM so if you guys are currently not with a network and would like to be with one again go ahead and leave a comment below and we'll give you more information. Now in today's news according to a report from App Analytics firm AppAnnie spotifies now the number one streaming app in the world. Now this past year Spotify has moved up in the streaming game when it comes to active users revenue and app downloads. In other news the new Tupac movie is now looking for a new director. Rumor has the legendary music video director Benny Boom is in negotiations to direct the new Tupac movie that should be set to start shooting in 2016. Now for those of you who don't know Benny Boom is a legendary music director who is one director of the year awards for his past work with Little Wayne, Nicki Minaj, Rick Ross, Drake and so many others. Now in other news Lovin' Hip Hop star Mandeces has been sentenced to eight years in federal prison for drug trafficking. Now as part of his plea deal Mandeces has also agreed to pay the courts over $171,000 he has earned from the Lovin' Hip Hop show as well as his Audi R8 sports car. Now in other news there's a huge rumor that Apple will not be including a headphone jack and it's news version of the iPhone, the iPhone 7. Now according to the rumor the headphone jack is supposed to be replaced by lightning connection earbuds. So we'll see how this goes. Hey guys we're back in my home studio and today's Freedom Partner Spotlight goes to a producer slash DJ by the name of Overdrive Music. Let's go ahead and check them out. Now regarding your music I would recommend adding more videos to your page as right now you only have a handful of songs or videos and I would love to hear some more music from you. Now regarding the music itself it's actually pretty good. One of the few things I would recommend though is listening to these songs I could tell that it needs a lot of punch, it's lacking clarity and right now it's pretty unbalanced. So one of the things that we definitely recommend is balancing out your beats, adding some punch, picking up the kick, adding some clarity by raising up your mids and your high frequencies and this will definitely add some punch and some clarity to your production. In the past I've actually spoken on the use of panning and the use of reverb to adding presence to your mix and your sounds and your production can definitely use some of this. You seem to keep everything right in the middle which is okay but I like to experiment, add some panning, add some reverb, give some really cool effects and that's going to grab your listeners attention a lot more than having a beat that's just kind of plain kind of dull and doesn't have any punch to it. Now I did notice that your latest video does have some vocals on it which is actually pretty cool but it seems pretty rough not mixed and doesn't have any attention paid to it when it comes to mixing these vocals and your production. So off the bat I would definitely recommend throwing an EQ, throwing some compression, adding some reverb and using some delays to give that vocal a nice effect going with your production. Now going forward on the Nova show and on the Beaton YouTube channel we will be having a lot more mixing tutorials to help you guys out when it comes to mixing and production and getting your songs to sound as best as possible. Now aside from that I would love to see your progression as a producer and as a DJ so please keep us updated when it comes to your music, please keep commenting and supporting the Nova show like you normally do. Now that's it for today's episode of the Nova show, please tune in on Friday for the next Beaton Partner Spotlight, until then you guys take care.


And today's little video is- I am so sorry. Polytechnic life tends to be like that. But you know what? It doesn't even matter. I am here in my room, this is my background, so it's all good. Bad hair days and how they affect our mental state. Now once upon a time I had long hair.  Pretty much every single day. And because of that I never really felt like I had a bad hair day. Up until last November when I decided that I wanted a change after my national exam so I got a haircut. It's been a year since I cut my hair.  I wouldn't say that I'm part of the 23%, mainly because if I was having a bad hair day I would just tie up my hair and pin up my fringe. Or if I really don't care I wouldn't do anything. I just let my hair down, go about my day, and then when I come home I would wash my hair. We're given the message that appearance is really important. Now the researchers at Yale University found that bad hair days impact self-esteem, increase self-doubt, and have a higher likelihood for personal criticism. An interesting thing to note is that we perceive our capabilities to be significantly lower when experiencing a bad hair day. The ladies say that they experience feelings of shame and embarrassment while the men say that they have low confidence and increased nervousness. Oh but it's not just social anxiety effects. People say that they start to criticize their personalities as well. So what do you guys think? Does having a good outward appearance affect our mental health? I definitely feel more confident and tend to be in a better mood if my hair felt great. Somehow I really think it does. What do you guys think? Comment below letting me know if you think that having a good outward appearance would affect your own mental health. And that is my time. Thank you so much for watching this video. The link to the article is in the description box below. Be sure to follow us here on our YouTube page as well as Tumblr and Twitter. If you'd like to follow me you can find a link or two to my sites in the description box as well. Thank you so much for watching this video and I will see all you beautiful people next time.