The following is a presentation of TFNN. The TFNN Bull Bear Training Hour. Every training day, live at 10 a.m. Eastern. Call now toll free at<PHONE_NUMBER> or internationally at<PHONE_NUMBER>. The TFNN Bull Bear Training Hour. Now, Tommy and Tommy O'Brien. Welcome, folks. Appreciate your growl and a problem with us out here. We have the Dow Industries up 244. You get the Nasdaq up 35. S&P's up 18.5. Gold contract up $4.20. Trading at $12.97 an ounce. We have Silver trading at $15.04 an ounce. Light Sweet Crude up $0.50. $64.08 a barrel. Notes and bonds. Attend your note down 11 ticks. That's $23.06, 30-year off 19 at $147.04. Now, both of these did break the swing low and they have some volume. Now, they have less volume and it will pull it up as to the strength where they broke out from. But bottom line is that you get some volume on the way down today. King dollar. King dollar down 400 ticks. Trading 96.410. The euro is at $131 to $1.00. The yen is trading out here at a price point of $11.87 and the pound is at $131.15 to $1.00. And where do we start, man? We've got a lot going on on Friday morning. I just heard that update, man. We're going to start with JP Morgan because when you took the... About $30 billion in revenue and about $10.00. In profit. In profit, right? That's intense phones. And the story wasn't even highlighting it because I guess it's just expected, right, that they pulled those kind of margins. But it jumped out at me, man, where I said, first, wow, they made, you know, $9 billion. And each of them, I think, was up 5% too. Profits up about 5% to $9.00 something billion. Revenue up 5% to $29.00. And that's at the parent expenses. To $29.00 something billion, yeah. Not bad. You've taken $30 billion. It only cost you about $20 billion. That's a good business. God, that's a good business. Especially if rates are where they are, right?  So you get JP Morgan. It's taken out at swing point there of the 19th. That swing point's at $108.00. You kind of... It's going to deal with this $111.00. That's your downdraft from December 4th. Okay. $111.60. It's a big number though, man. And then you get Disney. Yeah. So Disney's $7.00 Disney. No, not even. $6.99. The market just loves it. Quite a number. They should. They should because that is quite a number. It's... You know, this is where... You know, it's interesting about this. This is where, you know, some things aren't priced into the market. That was one of them. Yeah. Yeah. I mean, I think it's a brilliant move and that they are not going to be able to compete with Netflix across the board, right? Right. So they're only going to be kids and families. Right. So why are you going to pay the same price when Netflix is going to have children programming too? Sure. So I think they kind of figure that out saying, hey, listen, we might have a little bit less value to provide the Netflix right now, at least, right now. That's right. So we'll price it underneath and who can't afford $7.00 if you have kids and, you know, you're talking about a month. That's... What is that? That's $84.00 for the year. Right. Right. And for a Disney catalog, if you have kids, I'm sure that's worth it because they're going for the hundreds of millions, not the millions of subscribers. Yes. Oh, for sure. That's not what they're going for. I think that, you know, they... The Fox... They said they're going to lose money for five years on this deal. Oh, boy. Okay. Yeah. No, that's... I mean, that's what you're going to have to do if you're going to start competing with Netflix and make an impact across the globe for subscribers too. No, I don't. Yeah. Now, you know, we have the S&Ps up, but I want to go to the NASDAQ first. So if you want... Look at this, folks. So this is going to get really intriguing going throughout the day. And what I'm thinking is that, you know, the NDX, you know, bottom line can't break out of this number. So it's like, okay, why not? You know, we got to 76.65 out here today. You're at 76.43. If we get over and we go into the S&P, which with the S&P broke topside, no doubt about that, man. And the number that you want to keep... Well, I on the futures is going to be this 2900. You're 11 points over it right now. And we were, you know, basically 15 points over it. If we take a look at it, this battle's going to be on here for, I suspect, the first couple hours. And this is the first time we're over that 2900 since October, I think. Yeah. Oh, it's a big number, man. There's no doubt. I mean, that's... When you peak your head up like this, that's a good price spread right now. And, you know, we'll see whether the price spread can hold. But that is definitely a good price spread. We go into the Dow industrials. We take a look at the Dow. Well, interesting, too. Dow hasn't made it yet. So, 26,487. Yes. Yeah. Hey, there's a lot of moving pieces out here. There sure are, man. You got a big oil deal, right? Oh, yeah. Since Chevron by an Anadarko set 33 billion dollars. So, I guess that was a... What was it? Natural gas, liquefied gas type play, I believe? Okay. Yeah. Anadarko. Let's see. ANAD. Well, it's probably right there. What are you looking for the story? No. Oh, just a stock. Okay. Oh, $15. Now, here's the thing, though. Occidental supposedly bid $70. I'm not sure what the exact price tag of Chevron's bid is. Yeah. But I believe that 70 is above what the Chevron number came in at. And the CEO's going to get 64 million payout. Not bad. Let's see. It doesn't seem too astronomical in these days when you sell your company for 33 billion stock shares and, you know, what do we just pop in today as in... Oh, let's go back to Disney. Hold on. Let's do it. Well, you know why? This is crazy, folks, that this pop in Disney... I had the number. I think it's... I think it put 24 billion... Oh, there it is. Yeah. It put 23 billion in their market cap. Yeah. And it might even be up more than that right now. Yeah. That was at 9.30. Isn't that wild? Oh, for sure, man. For sure. Oh, my God. 23 billion. Yeah, they're quite a juggernaut, you know? It'll be interesting to see what happens, though, because what's going to happen is, you know, Aggress come out and said, listen, our motion picture, you know, business plan of launching in movie theaters is still going to remain, because we've made, I think you said, $12 billion off of like 12 films, maybe? You know, you add up their big giants with like Star Wars, and who is it, the Avengers or something? I mean, it's a staggering revenue. The audience is right here. So how... So look at this. Studio entertainment. That might be a 10 billion. I'm sure. Sure. And then, you know, you get the pox 24 and media 21. Yeah. So for what we're talking, that's... So they're still going to release those after the fact, right? They'll be that time window where they're going to be in theaters and you'll have your Star Wars launches and all that. They get one... But it'll be interesting because then you're going to have Netflix, though, that's producing huge movies. They're going to come right to streaming service that aren't going to go into the movie theaters. Right. And we know that Netflix covers everything. I mean, there's so many different programs. They have horror. They have drama. They have, you know, intense... Horror rated everywhere. Disney's not going to have any horror, I believe. Right. So if you're an adult, you know, you like good, intense movies. Right. They're not going to be on Disney for you. So I think that reflects in the price. Smart move for the $7. And if you have Netflix, folks, it's a new... It's great. It's our planet. It's amazing. And it's... And what's that about? It's just... It starts with... It just has... It's like a... It's like a National Geographic, right? Okay. Well, that's what I was wondering. Whether it was just a drama or no, it's a National... It just brings you around the world. Nice. Showing you around the world, the animals. Nice. It's... To be like that stuff, it's amazing. Now, since we're staying on... It took them four years. Okay. Because some of the pictures they got, you just can't believe. I'll check that out. What's it called again? Our planet? Our planet. Nice.  They're pushing it. It's the top of the deal, yeah. So staying on the streaming, I know you talked about a little bit yesterday, YouTube TV, right? Yeah. So Google, of course, Alphabet and all of that. $50 is going to be... Now, just for TV, as in just for cable, I say TV, YouTube TV. Right.  They have a great portfolio. I mean, some of my friends have YouTube TV. I think that's how we watch the Super Bowl, going back in January. Yes. So you get, like, local stations.  That's what made me think of it. You know, that they just bought that whole portfolio of discovery. They have Home Shop. National... Home of God. Yeah. Point being, as we go to break, $50. $50. That's a lot of money. I think $40 for high-speed internet. Right. So, boom, you're up to $90. Right. That doesn't include HBO. What if you don't have HBO? That's $100. Then you're at Netflix, $110. Disney Plus, you're at $120. There's your cable bill. I don't know. We'll see. I know. Stay right there, folks. Tell me that. Come right back. We have the dial right now of 225. Nasdaq is trading up 29. S&P's up 17.5. Come right back. The Taz Profile Scanner is the most revolutionary piece of trading software that you will ever try. Wouldn't you like to approach the markets with confidence? As you begin your trading day, it's likely that you'll be faced with lots of decisions. In order to make the best decision, the first thing you'll need is a strategy that will help you minimize your risks. 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You can still visit us at the same TFNN.com URL, but when you do, you'll see a new and improved homepage with a much simpler navigation, whether you're watching Tiger TV live in high definition or just accessing your newsletter subscriptions. We even have new pricing in six months and yearly options. Check out the new TFNN.com now and experience all the upgrades. TFNN.com, educating investors. Call now. Toll free at 1-877-927-6648. Internationally at<PHONE_NUMBER>. TazX up 29. S&P's up 18. Let's go to our man, John and Philly. What's happening, brother? Absolutely. Definitely. Happy Friday. What's going on? You ready for a good weekend? Trying to get rid of this last Midwestern snowstorm that just blew through here in the past couple of days. Man, oh man. It came all the way up to Philly? Oh, my God. I'm in the Midwest right now, Tom. Oh, you are. I see. Checking out the wheat fields. Okay, man. I like it. Spring wheat. He's out there checking out the spring wheat folks that got covered in snow last night. Yes, it did. Yes, it did indeed. I wanted to ask you about the NASDAQ 100, the NQ Futures and the Composite Index, the Cash Index. And just to let you know what I'm looking at or thinking about, so long as the Composite COMP hasn't yet exceeded the 81.30 high set, that was last September, October, as long as that has not yet been exceeded, I am looking for clues of reversals at any time. And I'm not forecasting, and I'm just searching that out, being cognizant that on this light volume kind of slowing rally and abrupt reversal, multi-day trading reversal could occur at any time. So I'm wondering if you can look at your 10-minute chart, Tom, and give us your read of things. What level, if broken, might signal such an event, please? So, you know, first we get the comp up, and you can see, you know, what's so intriguing here, folks, is that the comp and the NDX100, just on a consistent basis, brings the market up and brings the market down. I mean, that's all the growth stocks. Now, that being said, guess what? The last few months, this thing has been having a hard time. And if you take a look at this on a long basis, you can say, okay, listen, you know, we are right where we were in January of 2018. That's like sitting there, you get three different highs. We're very close to all of them. If we take a look at the futures, what is really unusual out here today, folks, is this, is that the futures themselves, the NQs, this is, the high of the NQs yesterday was 76.61. We got the 76.65, but what the NQs had done yesterday, after they got up there, they closed below it, and they're selling in these NQs. And, you know, that's saying that, yeah, the bottom line is that, you know, the NQs themselves, this baby can drag down the S&P. And the S&P only has to be dragged down like about seven points right now, and you're going to have a monster failure at the high. So I would say that, yeah, if you're, you know, going south, just stay south on the NQs right now and see if, if in fact, as we go through this day, but the NQs drag the S&P lower. You know, we're at, you're at 19. I believe the, the NQ, the S&P has got to get back inside this 2900 to really get a failure going. So, you know, it's, we'll see where the whole thing goes, but it's, it's definitely unusual, and it's showing weakness in the overall market with those NQs not being able to basically just not only get by the high, like blow by the high. Why not? Do you know what I mean?  And, you know, Disney's a lot of it. You got... J.P. Morgan, right? Some of those banks in there. For sure. Wells Fargo, I think is positive on the day. Not like JP, but yeah. Yeah. You got Anadarko up 15, Disney up 10. Versus Netflix pulling back. That's it in the NASDAQ, you know. Right. Yeah.  You know, as we commit to this close, because I, you know, just as we're sitting here talking, this S&P's having a hard time getting more bars. I mean, once you're over high, man, this thing should be plowing on. I mean, there's no reason the S&P couldn't be up 30 points. That's not, you know. Right. Very good. Yeah. Listen, thanks to you both. You all have a good weekend. You too, John. You have a great one, man. Have a safe one. And if we go take a look at some of these... Actually, yeah, let's go take a look at these, because these are big numbers, man. Yeah. These equities are up. I mean, it's a big day in terms of just fundamental news, right? The earnings, you got Disney. You got Netflix. You got the Chevron deal. Right. Yeah. Big numbers. Yeah. You got... So, Interdacos, the big one. 15. Disney's 10. Chevron's the opposite of that. Now, that's down six. Yep. JP Morgan's up four. Yeah. And then, look, Wells Fargo's up a buck right there. You got Bank of America up a buck. Only $30 stock. Yeah. Yep. And Bank of America is going up to the highs out here over the last six months. 30, 30, 14. You're at 30, 04. We... JP Morgan... Yeah, they're still buying it. Yeah.  And we'll get 23 million. You're going against the downdraft of 23 million. Yeah. So, let me just see this on a weekly. This is going to get... On the weekly, you're not going to get it, but let's see. 86 million. No, you need to worry about it. No, we're not going to get it on the weekly, but... You know, there's a... This... That blows my mind, actually, that... The profits that they took to the bottom line. Pretty remarkable, right? Yeah. So, let's see if we can go back. So, here's where we're looking. So, 9.18 billion profit. Right. Rising 5%. Revenue, right in line, 5%. 29.9 billion. And to get down to some of the bigger numbers. So, there's their profit. 265 a share. Yeah. The estimate was only 235. So, quite a beat there. And revenue exceeded by 1.5 billion. Yeah. And net interest income rising, 8% higher rates, of course. And now that's going probably to the earlier side of that quarter. Yeah, I think I saw a number that for the year, they're thinking that they're going to do net interest income at 58 billion for the year this is. Wow. Yeah, I know. It's a wow. Particularly because what you have is that the spread is not that dramatic right now. But guess what? Yeah. It has to do with how much money's out there. There's a lot more. There's a lot of money out there. That's the real bottom line. Lots of B billion numbers in their earnings as I spoke through. Isn't this amazing? I mean, it really is. It's like... Yeah. And that was... So, that's a big number. See that net interest margin? 2.57, that's big. Yes. Yeah. Now, that was the expectation. I'm not sure what they came in. They were just saying, but they're probably either around it or beat it or whatever. Yeah. They get so many numbers in here. Man, it's amazing. I know. Yeah. Let's see. JPM. Maybe that top one might just give you the full breakdown. There you go. Okay. So, that's going to be trading too. Fixed income and commodity, right? What is the fixed income? Yeah. Look at this. Almost every pot. So, investment back in the estimate was $1.63. They did 1... No, 1.63 billion. They did 1.75 billion. Equity, sales and trading, it was 1.73 billion. They did 1.74 billion. And there you are, right above that. There it is. Yeah. Net interest income, at least $58 billion. For the year. Just for the fiscal year. $58 billion. Yeah. Pretty remarkable. And that's the one that you don't have to do anything, folks. It's just what's the cost of money in and when they charge the money out. And so, they did commit it pretty close. 2.56 percent estimate was 2.57. Return on equity, 16 percent. Assets under management, 2.1 trillion. Trillion. Quite a number, man. Quite a number. Huge. Stay right there, folks. Tommy and I are coming right back. Our phone number is<PHONE_NUMBER>. We have the dial up 223. And that is the cup 34. That's the fees up 19. Come right back. Hi, folks. Tom O'Brien here. If you'd like to get my daily newsletter and market insights, then now is a great time to sign up for a 30-day free trial. Every morning by 9.30, I send out my morning letter to subscribers with market commentary on a variety of markets, currencies and commodities. To keep investors up-to-date on the day's trading action. Included in market insights are specific buy and sell recommendations for stocks, ETFs and even options, which stops and price targets included for every trade in my newsletter. If you'd like to try my newsletter at risk free for 30 days, then head over to the front page of TFNN and you'll find market insights under trading newsletters. 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This segment is brought to you by Think or Swim. For more information, just click the Think or Swim banner on the front page of TFNN.com. Now it's up to $222, Nasdaq's up $36, S&Ps are up $19.5, and Uba. Uba is running to the IPO window. They sure are, man. Like we said, lots going on, stories to cover today. So they came out with their fact sheet last night, right, in terms of really hardcore numbers, what they're doing, in terms of how many billions of dollars they're losing every year. But nonetheless, the founders, quite a payday, they're going to come into. So I'm sure we're all familiar with Travis Kalnick, who was the CEO. Looks like he's going to walk in. I read articles yesterday, somewhere between $7 and $9 billion, maybe. Interesting though, one of his co-founders, not one of, I think, the co-founder, Garrett Camp, he's coming in at, like, maybe $6 billion. And we're a joke in that he's kind of been able to lay low. Now I'm sure he's out there, right? I don't know where he is here, but every lay person might know, not every, right, but you know, maybe you've heard of the CEO as they've caught flak, they had to bring in the new CEO, right? This guy's caught no flak, and he's walking into $6 billion, and Kalnick's walking into $7 billion. Right. And one of the earlier employees walking into about 2.4 Ryan Graves. Big money. Oh, it'd be interesting to see what happens, man. And what happens is that, so, what they're doing out of a dollar, they're basically one of the else to say, and they only get 9 cents out of every dollar to start with, you know. And what do you mean by that? Between the, when you pay the driver, when they're paying for whatever they got to pay. Oh, they're getting 9 cents. 9 cents out of every dollar. Okay. That's a margin, basically. Yeah, so what they're pushing is that they're pushing that this platform is a new platform that we're all going to get used to, and we're going to be selling a lot more food, you know, on this platform. Yeah. So that's basically the promise. Sure. I suspect it's going to be, when you get a market that's up like this, the bottom line is that they're going to get plenty of buyers. The real question is what is going to be the valuation, right? Yeah. Let's just see if we search for Uber. I wanted to see if it comes up. No, it's not. Let's see what they have in here. Let's see if they got anything. Check it out during the break. I wanted to pull up. Well, there's a lot of stuff on it. Yeah. They'll... Because it's a... They're going to start having a symbol and so forth. They'll have an equity up there, right? And this is going to... This will go quicker than you'll see... 10 days or 2 weeks, 7 hours, a week or two. Because once they get everything in place, they get the placeholder. So the placeholder is what they did last night. We're going... And before they even do that, they've already shown all the states you see. Now it's like, okay, everything's in order. Here we go. The broker dealers will be on the road this weekend. Oh, definitely, right? They were on the road yesterday. Yeah, exactly. And you can see... Bottom line is that... So it's making its way. 56 is the ABC down. We hit 57-66 this morning. 50% from the high that we were at. March 29th. That's a staggering number. 50%. We just went from 90-60. 33%. Thank you. That's intense though. Only 33%. It's staggering. The other way to put it, I think my head was getting lost. You have to go up 50% from right now to get back to where you are. That's important to know. That's real. It's $30 off its high and it's trading at 60 bucks. Good luck getting back to 90 as Uber comes to market too. So let's go to this dollar index. Oh, look at that. That's the first time that we've gotten any... Okay, we'll see what happens here. So we get 10,000 contracts. And that's unusual, folks. When I said it's not unusual in the context of how it's supposed to be trading. That's totally unusual compared to what we've been doing. Look at it. All day yesterday, you only did 10,000. The prior day, we did 13. The day before that, you did 9,400. We're at 10,000. And you did break back underneath this February 15th, 96, 685. So this will get interesting out here today, especially on a Friday. Yeah, look at this though. The volume dried up intraday too. Look at that. Oh my God. So the last cell, was that 8 o'clock? Yeah, 810 this morning. So if you wanted to see how these high volumes like to get tested, it was testing that high volume over there from 96,405. Yeah. 96,405. But hey, this could be a start. That dollar will have a one day wonder of volume as it moves a little bit lower. And what do we add? I think we're getting 4.55%, was that where we're at? Excuse me, 2.55 was going to say 2.54 on the yield of the 10-year. Right, so here, I'm glad you brought this up because this is serious business today, folks. Okay? This is a break of a swing. Now you come into strength, but you can see that's a decisive break. You get a million contracts. So I brought it up when I heard 2.55. I said 2.55. We were just sitting at 2.45, not that long ago. So the swing has about 1.7. This one here, we're this broke. I have to change the actual future because we're rolling over. Okay, you're looking at a previous contract. Do you want to see the volume? Yeah. So you're coming into the strength from the 20th, which is 1.2223. The high of that is that 1.2317. So this is going to be important. Watching how this shakes out right now. You know, when I was talking to John, he was like, I think the S&P is going to have a hard time holding price. I'm going right back to that NASDAQ, man, because it's just a heads up that when that NASDAQ can't hold price. So we'll see how this shakes out. What will start happening, too, is as we get the earnings, though, and news stories, that's where you're going to get some of that diversion, which is what's happening today. You've got a big pullback from Netflix, it's been big, more than the S&P. Huge. And we had a question. Did United Health jump the creek? This is serious business. The health business is under fire, folks. Quite a slide for them. After this, we can get into the intraday. It was quite a slow demise yesterday. It just wasn't one jump. That thing traded lower all day, it seemed like. It did. And it was pounding into these high volume lows. So what are we looking at a week later? Big consolidation. So that puts in play 208.  Look at this. This is crazy, folks. This is a blast to the past. Because the 208 is the high volume low from February night that all the indices went to, but yet United Health didn't. That's what it's going after. IGPO? Look at that yesterday. It's not often this stock trades too quickly. There was just every single 10-minute bar there. They were like, we're going to trade lower all the way up until, what, 230? Then they got a little bit of a pop. And here, you want to see this? This is something simple, ABC down, intraday. You could just take the top of yesterday and be the most conservative. The top of yesterday is 246. Really, 247, if you're going to do it. 232, so we got, what, 15 bucks? Yup. And then 15 off 235. You can do that, yeah. 15, up 236. Yeah, yeah, so. Is that 221? Yeah, yeah. And that's a serious selling. Oh, definitely. Serious. We would just do 250, we're at 228. Watch out. Watch out.  Now that S&P, keep an eye on it right now because this is gonna be the number that bulls and bears gonna fight big time. Come right back. If you are in the CD market and looking for a secure investment, the Tiger First mortgage program may work for you. 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We get the Nasdaq up 25, S&Ps are up 14. Let's go over to the S&P for a second. This is always intriguing, man, when you get a market that there's no reason that it doesn't stay higher and then you just have divergence and this S&P, it's gonna try to get into this 2900. We'll see, it's gonna need more volume. Your first leg down wasn't bad, 29,000 contracts. Right now, you only get two minutes into this bar. Yeah. The Dow, let's just look at that Dow for a second because something's giving it up inside the Dow too. Not necessarily giving it up, but that's... No, they're all off their highs for sure. Actually, that's pulled back pretty good, right? It's off 100 points. And it didn't make its high of last week, folks, which is the 26,487. Can you go into the description for them? Well, bless you. Excuse me. Here it is. And I just wanted to see some of the movers or what. And that's where I mean you see, right? It's like big stories on both directions, all right? So you got Disney putting normal 70 positive points on the upside, all to do with their Disney Plus, not really do with the market, right? And then you got UNH, well, that might have to do with the market in terms of quite a 60 points, but then Chevron, not so much their deal market, not really liking that, putting about 45 negative points. Boeing, getting a little bit of a pop. That's interesting too, because I saw a new story this morning, we can go into Boeing and see what we got on news going with them. Southwest, at least pushing back to August. There, yeah, grounding, there we go. So there, no matter what, Southwest doesn't have them on the schedule at all. Grounding until August. So it's not a good story, right? You know, I haven't heard a good story for Boeing in a while, but none the less of five bucks. Yeah, so Southwest announced on Thursday it's fleet of their 737 MAX. Airlines will be grounded until at least August. They're removed from our schedule through August 5th, 2019. The adjusted schedule already in effect. That's pretty cool. I mean, I like the idea that they did that. Yeah, they're basically coming out because they don't know the FAA could come out in a month and say we're good, right? And they probably made a calculation, man. Do you want to be the gate agent in a month putting people on a 737 MAX? There's executives having those discussions, saying, listen, when they come back and Boeing is gonna come back and say we're good here, what does the airline then do to make sure their passengers feel like they're good? Yeah, and no matter what, they said we're gonna give it some time. Yeah, slightly, slightly. Okay, so let's go to the NQs for a second, NQM nine. Is S&P's gonna be negative in the next 15 minutes by the time we get off there? The NQs are dragging it down, folks. This is pretty wild watching this thing shake out. So the NQs just went from 76.65 to 76.32. Yeah.  You're right into the, this is going after the lower range. And you know, there's still gonna be a little more volume here. But, well, well. You better talk quick, we're moving fast. Exactly. Because this is what does happen when you get something that doesn't hold like this that, you know, as a technician, you know, a technician's rich to the fundamentalist, right, is basically when you get a break topside like this is that, you know, whether I think it should have gone lower because I think it should have because there's no volume, right, it had every chance to go higher. I mean, it's a break higher. It should go higher. And fundamentally, if you listen to what's going on, it should go higher. And then, so when you put that together though, that they're selling it is like a problem. It says, okay, so you really do have sellers up here. And, you know, so these are unique days when this actually happens, folks, you know, we've been up at this level for a long period of time. It got the break going, you know, it's still a break. I mean, if you're over 2,900 at the end of the day, you're broke topside, you know. But this battle will be on. That's why they call them bulls and bears. And how about Apple pulling back a bit today in light of a positive marker, but Apple down about buck 58. Oh, yeah. Yeah. Yeah. And that's not sure what's really hitting them, but another, while we're on it, I was reading about that YouTube TV. So $50, right? Right. If you pay for YouTube TV through Apple, you build $54.99, basically $55. Pay 10%, basically just as a convenience fee to, like, purchase YouTube TV through Apple. To use money. Yeah. Staggering out there when you start talking about that type of stuff. And one of my buddies was saying, I was like, what is, who is doing that? And he's like, convenience fee. And it's basically all it is. I mean, if you're in that Apple ecosystem and you want to run everything through the Apple Store, you can do that. Maybe it's a little convenient, five bucks, not the end of the world, but when you start talking percentages, man. And that's the battle that Apple's gonna deal with, because who in their outright mind is doing that, okay? So then you shouldn't be going through Apple. So is Apple gonna eventually lose business if they're charging for the same exact product in their ecosystem for 10% more money? And if they're not, then the other, you've already seen it when they're trying to build their streaming where the content providers are complaining, because they're saying you're taking 30%. Right. And that's where they're probably gonna say, well, you have to charge more money if you want to take 30%, right? I mean, that's obviously a discussion that YouTube had and saying, listen, if you want to charge more money then, interesting to see how that plays out in the years they come. It's amazing. Yeah. In that context, I'm gonna bring your way back now. Okay. I don't know if you were born then. Oh boy. Was it TV's or? No, the ATMs, okay? Sure. So when ATMs first started, folks, the bottom line, this is what's pretty amazing, they actually started in New England. Okay. And it started in Boston. And they were wondering then that people would, I think it was 50 cents the first charge. If people would actually go to an ATM, pay 50 cents to get it out. Okay. Well, needless to say, it went from 50 cents to three dollars to six dollars so quick and then another company bought it out, then all the banks got together and did it. But I remember that so well at the very beginning. Sure. And I think that these people, they probably have, even Apple has like, people who used to fees, let's just put it on. Let's see if we'll get it. You know what I mean? But the fees are huge, man. I mean, when you think about the fees, just that we charge these or MasterCod, that's why they make so much money. Yeah. You know, instead of paying cash, you know, we're paying 3% on everything. And that's why we get so much kicked out. Not often do you pay fees on something that you don't have to pay a fee for if you charge it at another website though immediately. Yes, I agree. That's the difference. It's like we are used to fees because they're almost a necessity whereas you fly in an airline, there's no like, do you want to pay for your bag with me or do you want to, yeah. They figure that out. But I don't understand how you're going to charge fees on a consistent basis, going on years, right? Where it's like somebody is eventually going to wake up and say, why am I billing for YouTube TV through Apple? I can just sign up through Alphabet, Google. That's the transit. I don't know how they're going to fight that one. For sure. All right, I can see that. We can definitely see that.<PHONE_NUMBER>. Let's go inside the MDX and see strength versus the weakness. So the strength out here is the check point software. It's up 3.8%. Aluminum is up three. Align is up two. Taken away from it. Netflix, 3.6 down. Monts, the beverage, off two. Regeneron, off 1.3. And Fox, off 1.2. Can we go to Netflix for a second? I want to see what kind of, so Disney popping more than $23 billion in the market cap. Let's see, so Netflix is a $154 billion company, I think I saw there. So 154, yeah, 154. What did we say it was down? 3.5% about, yeah. So 15 billion would be 10%. So you're down about five to six billion off their market cap, maybe a little more. No, not that bad. But in context, Netflix is entirely is only worth 150 billion. Disney just added 25 billion overnight. So that's saying it's going to be a comparison. They're happy in Disney headquarters, too.<PHONE_NUMBER>,000 up 189. Nasdaq's up 16, S&P's up 13. Come right back. I'm certain you are or strive to be one of the best of the best at everything you do in life. It's the most common trait that we tigers and tigers share. 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Get your two-week free trial to Basel's newsletter of the opening call today by visiting TFNN.com. This segment is brought to you by Think or Swim. For more information, just click the Think or Swim banner on the front page of TFNN.com. ["Think or Swim"] Right now, it's like up 20 S&Ps, up 15, and now the battle's gonna be on here. So your battle's gonna be on about five points in the S&P, folks. You know, we take a look at the NDX just through the queues, and you're gonna see that bottom line's not much happening here. Sideways move, small caps. We go take a look at the small caps. Let's see what... Sideways move also. And the small caps, the only major industry that hasn't hit the high yet. 159.50. Didn't we say the dollar hadn't hit the high yet, too? Oh, I think... What I meant by that is that, see, the dollar takers don't last very long. Oh, the recent one, that's right, okay, yeah, yeah. So the high we're talking about February... Oh, you're right. I'll just get this straight, sure. February, zero. Um, hey, we're in the earnings season now. That's the bottom line. Yeah, and you're gonna see some of this divergent that we're kind of seeing today, and I keep bringing it up, but you are. Yeah, that was a quick turnaround. Yeah, this is Wells Fargo. Market saying Wells Fargo is not exactly J.P. Morgan. They sold that down, so that's... Can we go to the news for them? That's what's going on there. I mean, let's see where...  Right. Oh, here, let's see. Is that gonna go... Well, maybe this is it. Oh, yeah. So sharply after CFO projects that net interest income will decline in 2019. So where is he? The CFO? Is he on the earnings call, maybe? Um, let's see if we go back. I always say it. Just pull it up and see if... see if that earnings call. I love those TD Ameritrade charts. There's your earnings at eight. Look at that. It took them all of... They better get off the phone, man. Is that a five-minute chat? This is a five-minute. So, it took all of... 10.30, it began. Yeah, it took all of 20 minutes. 10.25, yeah. Stay right there, folks. We got Fast Market coming up next. And we got our man, Mr. Basil Chapman, Steve Rhodes, Dave White. I'll be back tomorrow. I won't be back this afternoon. Have a great one, folks. Thanks, man. Well, I'll get them, folks.


So just to check that we're on the same wavelength, I'm going to do a small quiz for us. Me too. Here I have a plain simple helix with some residues there, green, blue. Here I have another plain simple helix boring just polyalanine. Which one of this will go into the membrane when I'm asking the translocon to process it? To make things easier, I'm going to add some charges to those residues. I wish I could do this in person with you, but hopefully you're all going to say that that's not likely to go into the membrane. And that's also what I would have guessed if I was just showing the sequence and didn't know the answer. And yet that is possibly the most important helix in your life. It's the reason you exist. This is part of a voltage-gated ion channels, and in particular the parts that senses the voltage. And those channels are, for instance, responsible for closing the egg once they're first realized. If this didn't happen, you wouldn't exist, and neither would I. It's also responsible for every heartbeat in our bodies. So it's kind of important. Why is that helix a membrane protein helix? Well, beats me, I almost said. This is the entire channel, and this is the helix. There are four copies of it, actually. You will probably hear more about these channels later. But why on earth is this charged? Well, this is a protein that should react in response to a voltage change, and that's an electric field change. It makes a lot of sounds to have a charge, because a charge in an electric field will feel a force. And if you now want to create a machine, getting it to move is the first step. That's, of course, why it helps create all these iron currents that, in turn, leads to nerve impulses and everything. And yet we don't know about that molecular mechanism and how it happens. The first person to realize the importance of the voltage sensor itself, I would argue, is Yasushi Okamura. So Yasushi is a Japanese researcher. He realized that the same type of helices occur in a few small organisms. CO9 test analysis, one of them. But in these organisms, he didn't only see a full voltage gate, the voltage gated ion channel. He saw a small voltage sensor only protein. That is a protein that consisted only of those four helices forming the voltage sensor. Occasionally, they occur in pairs and everything, but that's not so important. But the point is that the large tetrameria I showed you, they had six helices times four. But it turns out that we can cut off just the four first helices of the voltage sensor and it still senses voltage and can conduct EG protons. There is also a peculiar pattern here that the first helix is hydrophobic. Second is, sorry, first helix is hydrophobic. Second is hydrophobic. The third helix, well, maybe halfway. But it goes in because its peers are already there. The fourth helix, definitely not. It's even hydrophilic with all those charges. So somehow the previous three helices help stabilize the fourth helix. I think I have an illustration of the structure of it. Yes, I do. The helix here in the rear, the blue one, is the one that has all those arginine side chains that is responsible for somehow moving up and down. And people fought a decade about this before we eventually converged on models. So one way or another, they will have to change the structure to open the central ion channel. There are a few different models, but we and some others believe that the helix should move roughly straight up and down, maybe rotate a bit. There were people who assumed that there should be a paddle moving straight through the membrane. And there have also been ideas that maybe you just had some sort of tilting mechanism that you don't really move up and down, but you're exposed alternatively either to the inside or the outside. I would argue that we won and the people eventually agreed on our model, but I bet other people will disagree with me. How do we know that that's true? Well, the idea here is that if it's moving that way, those positively charged residues should be stabilized by the lipids, right? That's why it would not work with negatively charged residues because there are much fewer positive charges deeper buried in the membrane. Rod McKinnon came up with a very smart way of testing this. So they took this voltage sensor and then they expressed it in a special membrane that was not the normal mix of all this Twitter ionic lipids, but that you had in particular only a dotap lipid. It's a bit strange lipid with only a single positive charge. And this simple, plain proteins that worked great when expressed in PC head groups, if you just had them in dotap head groups, the protein doesn't work. It can't open. Now, you could argue that might be due to the lipid complete misfolding or something, but the neat test is that if you then just titrate and add a few drops of PC normal head groups to it, it starts working again. So it's the presence of negative charges fairly far down in the lipids that helps stabilize this voltage sensor either in the open upstate or in the closed downstate, which is a remarkably cool biological process. We know much more about this today. People have been able to do neutroscattering studies, molecular dynamics simulations. And in principle, I would argue that we have a pretty darn good consensus about the closed downstate two that we would normally only see when there is a polarized membrane. And you can't really get that in a crystal. We've also have good models for what happens when we say mutate this ratio. We know that this is all electrostatics. So in theory, if I start to alter some loops in the protein, well, if I introduce or remove charges there, I'm going to change the local electrostatic environment. And that means that it's going to be either easier or harder to move my four charges up or down. And that makes sense. If I measure this in electrophysiology, systematically, it bears out exactly where I place these charges. So it's a plain simple electrostatic problem, and yet one of the physiologically most important processes for us. Let's have a second look at what they learned. You already saw this one. Let's look at it from the top. Do you see this helix with the arginines exposed here? Now, you could say that in a real vaulted gaited ion channel, you're going to have the pore domain and stuff here. So this won't really be exposed to water. But remember, Yasocio-Kamura's result that they can exist in isolation, just these one, two, three, four helices. And in that case, you would expose the side chance here to the protein. There is no way that can happen. Sorry, the side chance here to the lipids. There is no way that can happen. The way we solve that is exactly the lipid head groups. So here, the helix is in its upstate. And in the upstate, these two residues up here, in particular, they have to form hydrogen bonds or salt bridges even to lipid carbonyls or even the phosphate groups in the lipids. But that's going to make them quite happy. Maybe the lipids have to stick down a little bit, but they don't have to interact with hydrophobic residues. Essentially, they snort a lot of it. These two other residues here in the middle, they are facing the red residues here, that is aspartic acid. So they form salt bridges and are quite happy. If we now move this entire helix down, they trade places. These residues that were previously out here, they're now going to face the red ones. While the residues that were previously facing the red ones, they are now pointing down and interacting with lipid head groups on the other side. It's a remarkably beautiful example of how lipids stabilize membrane proteins and membrane proteins get their function by moving between different states and using that.


Hello and welcome to the session. My name is Mansi and I'm going to help you with the following question. The question says find the derivative of the following function 3 cot x plus 5 cosecant x. Let's start with the solution to this question. Here fx is given to be 3 cot x plus 5 cosecant x. So f dash x will be derivative of this function so f dash x will be equal to 3 into dy dx of cot x plus 5 into dy dx of cosecant x. Now we know that dy dx of cot x is equal to minus cosecant square x and dy dx of cosecant x is equal to minus cosecant x cot x. So we put these two values here and we get f dash x is 3 into minus cosecant square x plus 5 into minus cosecant x cot x. This is equal to minus 3 cosecant square x minus 5 into cosecant x cot x. So this is our answer to the question. I hope that you understood the question and enjoyed the session. Have a good day.