All right, so I'm going to talk about using persistent homology to generate features for drug discovery, but there's sort of, in some sense, it's just one application of persistent homology, and there are other applications, and like, I think you can learn something from this even if you're not particularly interested in drug discovery, maybe you'll learn a little bit about persistent homology, and of course Dimitri is a world expert on persistent homology, if you have any follow-up questions or issues. So what's the context for the problem that we're looking at? So we want to create new drugs to solve diseases, to cure diseases, right, and to do that we have to find new compounds to run through drug trials, right, and before you start just giving people drugs, you test them, you know, in labs, on cultures, on cell lines to to make sure that they inhibit the things you want them to inhibit, and then before you do that, you need to like the space of all possible compounds is too large, so you need to find some way to filter that down to a potential set of compounds to actually try to solve the problem. So you kind of start with this kind of like in the world of all compounds, which are the ones that I want to be looking at. So we're going to be looking at this step here of like sorting through compounds to find potentially promising ones. Now as far as drug discovery goes, in some sense, this is like, this is a part of the problem you can tackle with data science and math and statistics, but it's like, it's a very small, you know, we should understand it's a very small piece of the problem, and that the actual, you know, drug development process is, you know, a decades, multi-decade long process to actually do this for real, but yeah. And then maybe like, I'm going to be kind of dealing with a very constrained data set and a filtering problem, but there's nothing to really stop you from stepping back and doing something on a much larger set of compounds. It's just not, it's just not something that I did in this process. So this step is called virtual screening. So why do virtual screening at all? So actually testing, physically testing compounds is very expensive. So virtual screening is a computational approach. Typically it's going to be based off of like biomedical knowledge. And the reason I say that is that I have no like particular biomedical knowledge. So typically you would have a real expert in some chemistry, biochemistry, etc. Virtual screening, it's a way to reduce costs. And our typical goal will be something like, you know, we would like to get 90% of the potential inhibitors and maybe reduce the, you know, total space of compounds to 10% of the original data set. That's like sort of a ballpark of what you kind of, what you want to do. So there's lots of methods. Again, like, I'm not really an expert here. I did this work in collaboration with an expert. And he told me, these are the methods you should put on your slides for other competing things. And the message is, though, that they're like, they're very detailed calculations, maybe they're quantum mechanical or semi classical or, you know, that there's a lot of input from chemistry and biology, but they're very detailed calculations about particular molecules. And what we're going to do is kind of do something, it's like philosophically a little bit different, which is that we want to organize molecules and extract something about particular molecules from how they sit in the space of all molecules. So rather than kind of getting into the nitty gritty details of a particular molecule, we want to have some sensible way of organizing them so that we can say over there are the antibiotics, over there are the chemotherapy drugs, right? Like that's kind of this like spatial view. And that has to do not just with a particular molecule, but its relationship, right? How it sits relative to other molecules. So that's kind of going to be our approach here. Okay, so again, our goal is to take a database and find the set of relevant bioactive compounds. So we're going to look at the particular, a particular sort of kind of problem, which is a DHFR inhibitor. And the main sort of takeaway from this slide is that DHFR is needed for cellular reproduction. So if you can stop it, right, you can, if you can stop E. coli from reproducing, you have an antibiotic. If you can stop cancer cells from reproducing, you have something to treat cancer, right? So we're going to target a certain thing that's needed for cells to reproduce and try and block that, stop that from happening. So, so yeah, so there's cancer. So the same, the same pathway exists in multiple different kinds of organisms. So it's not just in humans, but you can target, so if you're targeting human cellular reproduction, you're going to be developing a cancer drug. If you're developing bacterial reproduction, you're going to be targeting antibiotics and then you can also target things like malaria. So in general, like this, this method of DHFR inhibitor, it's like a very promising ground because there's lots of potentials for drugs to have applications in a lot of different domains. That said, a particular drug, you really want to do one of these things. You don't want the, when you give someone antibiotics to also be killing them, right?  You don't want like overlap there. And so that's going to kind of, that's a little twist that kind of complicates our story a little bit, is that the, the, the process of inhibiting is very similar across these different organisms, but there's some subtleties that will, that will make a, that distinguish them. And so that's just kind of confounds and makes our problem a little bit different, more difficult. And so, yeah. So in fact, this is sort of, this problem is interesting also, like historically. So methotrexate is a DHFR inhibitor and it's considered the first historical example of successful cancer drug design. Meaning that people really, they, they wanted to go after this particular thing and they designed a drug to go after it. And so on the top we have the, I believe the actual thing and then on the bottom we have the inhibitor that's going to stop this reaction from happening. And I could have that backwards. I actually, since I made the slide, I forgot which order. I'd have to look at the tag and like look at the file name that I'm loading the two pictures. I apologize for that. And then here's one that's like similar, but, but doesn't work. So this kind of design, this like designing drugs to do things is very hard, right? So a lot of knowledge, biological, biochemical and years of work goes into doing something like this. So methotrexate was designed in the 40s and 50s and it's still used today as a, as a, as a drug. It has bad side effects like hair loss, ulcers, right? These are things that maybe if you, you know something, you know, or maybe we all from popular culture know something about chemotherapy like these are all really bad side effects. Why do we use drugs with these side effects? Because it's really hard to design new ones that don't have these side effects, right? So, so the fact that we use something, you know, for many decades with awful side effects is like a testament to the difficulty of this problem. And then there's this, there's this like twist to this story, which, which actually is my favorite part is, is that the design, when they finally were able to, to use x-ray imaging of, of like, of how this compound was actually binding and stopping this reaction from happening, it was doing it backwards from how it was designed to do. So in a certain sense, the whole thing that like this like successful design story ended up being a story about luck, right? That like it, it happened to work, but it just works backwards, right? And, and that's again, like, like this is, this is a hard problem, even when you're successful, maybe you just got lucky. So this is like, yes, yeah, you sound like a more of an expert on this than I am. No, that's, that's right, yeah. But yeah, that's right. Okay, so it's not really to the rescue. It's, this is more of a like, I don't want to oversell this. This is like a slide I stick in here for computational topologists. So they feel good about the work they're doing. In this case, Dimitri's the only computational topologist, so it's, it's a little bit of a pointless slide. I apologize for that. No, his work is so self-evidently valuable. It doesn't need, it doesn't need me calling, you know, calling him out. I mean, I will say there was a period like, you know, computational topology was, I would say it was developed before it had great applications, like, like the applications weren't great. So, so like, it's nice to have good applications. So this, this was, yeah, anyway, I should stop talking about that. So, all right. So for, so for each, so, so what is, what are we going to do? Okay, so for each chemical compound and some database of chemical compounds, we're going to calculate a set of topological invariants called barcodes. Yeah. We're going to take a metric or distance on the space of barcodes to assign a distance to the space of chemical compounds. And then what we want, like what we're hoping to see, and I should be clear that, like, I was like, and this is, by the way, this is like how data science is done. I was like, I have this idea. And like, I hope it works. And the only way is to try it. Like, there's no reason to necessarily believe that it's going to work. So you hope that the compounds with certain, you know, properties, bio, biological properties will be grouped together, sort of physically, geometrically in this space of all compounds. So why, like, can I say, you know, like, retrospectively, like, why did that happen? I don't know, but it did happen, right? So we'll see, we'll see that. And that's how a lot of data science problems go. So, yeah. So, and again, this is, this is a little bit of a different perspective that I'm sort of emphasizing here, because I think it's one of the gains from using these techniques is that we're not just looking at individual compounds, but it's the compounds relative to the other. It's finding the, the, you know, antibiotics grouped together in this compound space that's interesting, not sort of the particular barcodes necessarily of an individual antibiotic. Okay, so we we're using a standard online database of compounds. There's some basic things that we know we need to have that we use to pre-filter the database. And then there's also, we did a literature search to find all the known inhibitors, and those are going to go into our data set as like the outcome that we want to predict on, right? The things that we think know things about are the ones from the literature search. Okay, so persistent homology. So I'm going to tell you now how I make these topological signatures. So, so this year is sort of a technical slide, which is that when you have a series of inclusions of a space, you can track topological information as it sort of passes from one space to the next in the inclusion. So this is like, this is like, this is as technical as we're going to get here, but I'm actually going to like, forget that for a moment, like this is what that means this this issue of the family of inclusion. So here I have a toy, a toy chemical compound. So these dots are the atoms, and I'm going to create now a barcode for you one of these topological signatures from this toy arrangements of atoms. What I'm going to do is I'm going to connect atoms to the nearest neighbors, right, like the ones that are distance, you know, half from each other, the ones that are distance three quarters from each other. And then when I get a complete simplex, so that's like a triangle, when I get all the sides of a triangle filled in all the edges, I'll fill in the triangle as like, as part of the space. So as I've increased this distance parameter, I get I start with the points and then I'm like connecting things up. And what you notice is that as I connect things up, each space is included in the next one along the line. And that's kind of the machinery of persistent homology will then create the barcode for us. So what does this look like? So here we have our atoms. These are the closest atoms. They would be the first ones connected. Then I connect these these ones further out. Notice now I have I have these loops, right? So I started with eight points. Some of those got connected. At the next step, I end up with everything connected and I end up with some loops. And then if I keep going, those loops get filled in. Right? So I'm going to record this information about the connected pieces and the loops. Okay, and I'm going to summarize that with what's called a barcode. Okay, so H naught means connected pieces. So that top barcode is recording information about connectivity. H one is going to record information about the loops. At the beginning, I have eight lines for the eight points, and no loops. So there's nothing on the loop line. I connect that up. Some of those points connect up. So the their connected components die. So I end up with six.  But I started with eight connect or sorry, not eight, nine connected components. And now I have seven. So I have two of those bars died. Seven live on. Right? And then at the next step, I get these loops. So all of a sudden in the h one, you see that there's a loop. And then when I keep going, those loops connect up and they die. So those those loop lines are short because they only exist for a certain set of parameters. Right? So I'm tracking these features about loops about connectivity, as I change this distance parameter and connect up the points in the barcode. So this year is a particular this is one particular example, which is filtering by which I'll call that's the rips filtration. And I'm using distance distance to the nearest neighbor to filter the space. But there are lots of other ways I can filter the space. There's the death. So another way is I can say, I'm going to filter from the edge of the compound down towards its middle. Right? So what do I do that? Is that I assign the middle of the compound is two. And then as I move away from there, I have some decreasing function. And now I'm just going to filter by sub level sets of this function. So what does that mean? Again, we look at the barcode. I start with the lowest values, which would just be the things furthest away from the core. And then I add in more points. I still just have two pieces. And then as I continue this process, I still have two pieces. But now I also then I have some loops. And then once I get to the middle, one of those pieces die. So I have one piece, right? So that's why the barcode ends I have one piece. And then those loops kind of live on forever. So they just once I have two loops, they never disappear in this view of coming from the edges in. Right? So so this is this process is that different filtrations give us different barcodes. So what we're going to want to do is now we this is this is sort of like feature generation, feature generation in this context means coming up with filtrations that capture meaningful information about the chemical compounds. So the ones we've already and the thing to note here is that is that this this is not this is not a magic, like dark box that you can't look into different filtrations tell you something that you can like, you can read off information about the chemical compound from these barcodes. Right? So for the first one, right? We learned about the number of atoms, which was the H naught at the beginning. And we learned about the size of the void, right? There's the size of the voids corresponding to the length of this H one bar, right? That that if there were really big circles, those bars would be longer, because they would it would persist over a larger set of parameters distance parameters. So we can learn something by looking at the barcode about the compound, right? And a different function gives a different barcode that reads off something different about the compound. So in this example, we learned that this compound has two kind of flares far away from the center, and sorry, two flares, and that the circles are far away from the center. And we know that because the circles entered the picture long before the compound itself was connected. Right? So we learned that there's like circles away from the center. Right? And now we just we use sorry, we're going to skip these slides. We're going to come up with functions on the atoms, use the filtration, these filtration of these functions to make barcodes, and then use those barcodes to create a space of compounds. So I've explained that how like how sort of we get these barcodes. So we're actually going to end up with a lot of barcodes for every atom, for every molecule. And this is actually this is like a two sided coin. It's, it's nice because it means that that the sort of it's very easy to come up with functions that tell us something about these atoms. But it's bad because we're actually going to have trouble like handling all these different barcodes. And it becomes a little bit of a of a of a mass. But we'll get through it. So one of the ways we get lots of barcodes is that there's more than one notion of distance, floating around. So I said, we're connecting things that are a certain distance away. But there's at least two very natural distances in this problem. One is just thinking of the molecule as being in three dimensional space, there's like the Euclidean distance between the atoms. But there's also you can think of a molecule as like a connected graph with bonds being the edges. And then you the distance is like the distance along this graph. So there's more than one distance floating around. So for every function or for every like, yeah, so so we're going to want to consider both of those different kinds of distances. And now we're going to filter them a different way. So there's the distance filtration we already talked about. But we can also get other kinds of filtration. So the rips filtration is what we we've already really talked to. We already talked about since the centrality fence filtration is also called eccentricity, just like one over or minus or minus one over right depending on your kind of standards. So we've already looked at that in great detail. So some other kinds of filtration you might consider are by atomic mass, where you put in either the heaviest or the lightest, probably heaviest makes more sense the heaviest atoms first, and then you add in sort of progressively lighter ones. And you see how the the molecule connects itself up. There's also you can look at partial charge. So this is how charge is distributed over the the molecule, and you can filter by super and sub level sets of partial partial charge. And and sort of those those are explicit those last two are explicitly chemical, meaning that they sort of explicitly dealing with something about chemistry. But the other ones were also really kind of implicitly chemical, because when you're filtering by distance, this has to do with bond distance, this has to do with how the the molecule has kind of warped itself up twisted itself up in space. So so chemistry kind of is is really permeating all of these different measurements. Then there are some other there are like various parameters that you end up having to choose to kind of do this cut off parameters, what's the underlying complex that you're filtering and and doing sort of trying different parameter choices. So I'm just like trying them all and kind of throwing them into into the ML toolkit leads to this of the proliferation of lots of different barcodes. Okay, so we end up at the end of this process with hundreds of barcodes for each compound. Now what we want to do is is so this is every compound has its collection of barcodes, we want to use this to make a distance between chemical compounds. And there's two very natural distances floating on one's bottle that and one's Wasserstein. And here this is like their representation as formulas. But there may be easiest understood as just edit distances between barcode diagrams. So if I have these two barcodes and I want to match them up, I try and find the best matching, right, where where the best matching is like just alignment of these bars. And then this is the cost for the matching, which is going to be the distance between the barcodes. So this is this is just how they the barcodes kind of mismatch. And the the difference between the two distances for bottleneck, you just take the maximum mismatch. And for Wasserstein, you're just summing up all the mismatches. So so after that process, we we have now a metric space of chemical compounds. So we did the thing we said, which is that we were sort of geometrically organized all these compounds. And what we're looking at now is a visualization of this metric space. And what we want are, like, have we captured something about the bioactivity of the compounds. So what ends up happening is that all of the known so from the literature search, all of the known human inhibitors end up being mostly in that upper upper flare over there with a couple sort of in these these other spots. And I can look at the ones for E. coli, and they're kind of mostly elsewhere. Right so red meanings means that there's a lot of E. coli inhibitors in that region of the space. And you'll see there's kind of a little mixing up at the top. But like mostly the E. coli is very distinct in this viewpoint from the human inhibitors. So this is a visualization, which is nice. We want to quantify, we want to quantify our ability to to separate out, not just visualize the ability to separate out. So this the the space of barcodes form. So what do I need to do? Most machine learning kind of tools require that you you give it vector information. So I need to write. So right now I have this abstract metric space, I have these barcodes, which which consists of, you know, bars, which are just unordered lists of birth and death points. Right. And I want to turn that now into some nice vector representation. So I can feed it to, you know, whatever machine learning method I want. So to do that, I'm going to use the fact that the space of barcodes is itself a geometric object. It's a algebraic variety. It turns out to be like a little bit more the story of like, exactly the details there is complicated because it's an infinite dimensional variety, which is like, as soon as I say the word infinite dimensional, you say, whoa, and that, you know, so it's got some complexity. It's it's singular, which makes it more complicated. But then it turns out when you consider all of the infinite dimensions, like all the singularities kind of paste together, and you end up with something really kind of nice. And the point is, you can just write down its ring of functions, which is just some examples here. These are some sort of simple examples. The thing to notice is that like, so x is the birth of x i is the birth of the ith bar, y i is the death of the life, ith bar, so where it starts and where it ends. And so x i plus y i is not a legitimate function, because when the birth and death go to zero, the function, right, the bar disappears, right, when it has zero length, it's no longer a bar, it's gone. And and I need the function should not have a value on something that doesn't exist. So so anyway, so here are some examples of this ring of functions. And just by taking polynomials up to a certain degree that leave in this sort of specific ring of functions, I can embed now the space of barcodes into some Euclidean space and apply regular machine learning. So in this case, I'm going to use a support vector machine. And so when I do that, this is the confusion matrix between the different classes of compounds. So there's the human inhibitors and the E. coli inhibitors. And then I also have pneumonia and another kind of inhibitor, another kind of target, which I apologize. I briefly slipping my mind and you can see that that so this is the confusion matrix. And the point is most of the weight, most of the value support is on the diagonal. We do a great job separating out humans and E. coli. And you saw that sort of visually in that diagram that that the E. coli and the humans were targeting compounds when different parts of the space for the pneumonia and whatever the other one is, there's like a little bit of a confusion going on there, which you can see. And the point is, is that this ability to separate out compounds by the by the species targeting is basically comparable to state of the art computational chemistry, which is like just the sort of many orders of, you know, five orders of magnitude more compute to do the kind of molecular simulations compared to calculating these barcodes. And that was a made up number five orders of magnitude. It's way more complicated. And it's at least that much more complicated, probably even more. Okay, so what was the like, the goal here is that so from a set of chemical compounds, we, we created this kind of set of barcodes, we used a metric on the barcodes to organize the compounds kind of geometrically into a space of compounds. And then we can use the structure of the space to look for potential new compounds. The reason we think that might work is that for existing compounds, we've managed to kind of group them into distinct groups. Yeah, and so then there's this this piece, which I think is, is maybe a little bit, which I'd like to be more appreciation for, which is that we're using like other compounds to measure, right, like your space in the your spot in this space of compounds has to do with your relationship to other compounds, right. So rather than just thinking about the particulars of a particular compound has to do with its like relationship to the other other compounds, which I think is is really interesting. There's this global space of compounds that you can start to try and understand. So there's like lots of ways that this project is is like, is incomplete. And there's like a lot of work to be done. So there's this. So one of them is that I'm considering these filtrations individually, right? So when I have a function like distance or centrality or partial charge, I'm sort of taking a filtration with just respect to that one thing. But like what how does partial charge interact with centrality? I would like to take both of these filtration simultaneously to understand their interactions with each other. So that's something that on the math side would be called multi dimensional persistence. And the story there is kind of the does a lot of work to be done. It's really still still open how to do that properly. And in the right way. One thing that we really would like to keep, because there's a lot of benefits is, is this idea that when you do have a filtration, you have a bar code some invariant, and you know how to compare invariance from different spaces. And so that was one of the things here that it's a little bit of a subtle point. But the bar codes allowed us to take the topology of each of each different right, the chemical compounds, there's no direct way to like compare the chemical compounds. But the bar code provides a uniform language where I can now compare the topology of differing compounds. And so that that ability to compare invariance is really important. So Dimitri, I know, because he's about to release Dionysus to once his documentation is finished, that he's going to work on this afternoon. So faster, more efficient, persistence calculations, and, and there's lots of work on the chemistry side to what other functions would be useful to measure information about about the the compounds. Yeah, so I think there's like an intriguing idea here that that. So so I don't really work on this at all anymore. But but the reason I go around giving talks on it is like I really want, eventually, I'm going to talk to a chemist who's like, I'm going to do something with this. Right. And I really, you know, what what are like, what are we capturing about the compounds with these, this metric space of persist on on bar codes. And like being able to more directly say, yeah, there's three, you know, in the E. coli group, there were four different groups of of E. coli inhibitors, like what are those correspond to chemistry? A very sort of cursory examination of this question is not completely obvious. There's some subtleties in these bar codes that's causing them to break out into those groups. But I think that that could be really, really interesting. And particularly because the bar codes themselves are so well, for me, at least, they're very intuitive. I understand like maybe maybe like we went a little fast here, but but the point is that like, they're not some weird feature. They're a feature that that that like has direct connection to the geometry of the compound. If you understand them, you can like read information back and forth. And I think that that that itself is having features like that is really interesting. So all right. That's it.


Dear Lana, today I am going to discuss the topic operators and expressions. This topic is from the course computer programming using C-language. Today I am going to discuss mainly the definition of operators, the definition of expressions, what are the different types of operators using C-language and the precedence and associativity of operators. Now, what is operator? Suppose an operator is defined as a symbol that specifies the mathematical, logical or relational operators to be performed. C-language supports various types of operators and now let me discuss what is operator and what is operand.  Now what is expression? An expression is a combination of variables constants and operators written according to the syntax of the language. In C-language every expression evaluates to a value that is every expression results in some value of a certain type and that can be assigned to a variable. Let me write an expression a plus b this is an expression result of these two variables is stored in this variable sum this is an expression it is a combination of operators and operands and sometimes constants. Now I am going to discuss the types of operators C-language supports various types of operators and those are first one is arithmetic operator arithmetic operator next logical operator relational operator, convolutional operator, midrange operator, union operator, size of operator, unary operator, unary operator which includes increment and decrement of operator increment and decrement of operator these are the operators used in C-language. Now let me discuss the arithmetic operators arithmetic operators can be applied to any integer and floating point numbers. The addition, subtraction, multiplication, division these arithmetic operators perform the usual arithmetic operation in C-programs but the modulus operator performs differently. Modulus operator is denoted by the percentage symbol and it gives the remainder of the division and division operator gives the result of a division. Let me discuss with an example this is modulus operator this is an example of arithmetic operator and this is denoted by this symbol percentage. Suppose 5 it gives means it gives the remainder this division operator division operator is denoted by this symbol and suppose 5 divided by 2 it will give 2 result of this one division operator this value and this modulus operator gives this value remainder of a division. So dear learner I have listed all the arithmetic operators in a table let me discuss that. Suppose I have taken 5 in the variable a and 2 in the variable b then the plus operator gives a plus b equal to 7. Similarly the subtraction operator gives m minus b 5 minus 2 equal to 3 multiplication gives a into b that means it will result 10. Similarly division operator gives the result of a division that means 5 divided by 2 it will give 2 and the modulus operator gives the remainder of a of a division a mod b equal to 1. I have written the use of all this arithmetic operators in a simple C-program it is written in this C-program here in this C-program initially I have declared 2 variables n1 and n2 for storing the numbers. Then there are some other variables like sum, sub, MUL, mal then division and mod to store the result of this arithmetic operators. First I have entered the value of 2 variables in the variable n1 and n2 then in the sum variable the addition is stored then in the next next statement the summation is displayed with the help of the printf statement after that sub equal to n1 minus n2 that means the subtraction of the two numbers is stored in this variable sub. After that the difference is displayed with the help of a printf statement like this the multiplication division and modulus is calculated and the output of this program is like this. Here the input numbers are 10 and 3 the sum is 13 the difference is 7 the product is 30 and division is 3 and the modulus is 1. This is a simple example of a C-program where I have shown the all the uses of arithmetic operators. Relational operator can be used to determine the relationship between the operands. A relational operator is also known as the comparison operator. Relational operator returns true or false depending on whether the conditional relationship between the two operands holds or not. True means the value 1 and false means the value 0. Suppose I have taken an expression x less than y if x is less than y it gives true value that means 1. If x is greater than y then it gives false value and that is it will give 0. Here I have shown all the relational operators in a tabular format first one is less than second one is less than or equal to third one is greater than fourth one is greater than or equal to then equal to operator then not equal to operator. Equal to operator is expressed with double equal to sign and with the help of single equal to sign we in C language only assignment operator is expressed. Here I have shown some examples 4.5 less than equal to 12. As 4.5 is small as compared to 12 so it is a true statement so it gives true value that means 1. Similarly minus 6 is greater than 0 it is a false statement because minus 6 is always less than 0 so it will result 0. Similarly 10 less than 7 plus 5 here 7 plus 5 is calculated first 7 plus 5 is equal to 12 10 less than 12 it is true so it will give 1 and in the next statement 4 is equal to 2 it is false so it gives 0 value. Now I will discuss the logical operators. There are 3 logical operators in C language these are logical and which is denoted by this Davoon Apartheon symbol then logical or which is denoted by 5 logical not this is denoted by this negation symbol. These are the 3 logical operators used in C language. Logical and operator is used to simultaneously evaluate 2 conditions with relational operators. If the condition on both sides of the logical operator is true then the whole expression is true. Suppose I have written a statement if A greater than B and A greater than C then I will store the maximum value on this variable max. In this expression this is an expression this is the left hand side of an expression this is the right hand side then of an expression and this is the logical and operator. If both these conditions are true suppose A is greater than B and suppose this is also true and suppose this is also true then only A is assigned to max both conditions should be true in case of logical and if one is false if this condition is false or this condition is true then it will not come to this statement. In logical and operator both conditions should be true and the truth table for logical and operator is like this. Suppose this is the first expression this is the second expression and this is A and B. Suppose first expression is 0 that means false second expression is also 0 then after logical and the result will be 0 first expression is false second expression is suppose true that is 1 then the result will be also 0 first expression is true 1 second expression is 0 then the result will be 0 if both the expressions are true then only result will be 1. This is the truth table for logical and operator. In logical or operator if one or both the conditions on the left hand side and the right side of the logical operator is true then the whole expression is true. In logical or operator if one or both the conditions on the left hand side and right hand side of the logical operator is true then only the whole expression is true. Suppose in this expression I am modifying this with the logical or operator in case of logical or operator only left hand side or right hand side only one condition is necessary to be true. Suppose this is true this is false then max will be sorry the result will be true that means 1. If I express this in this truth table for or operator here this result will be sense like this 0 0 it will give false value 0 0 1 that means false and true it will give a true value and true and false it will also give a true value and true true it will also give true value. Only one expression is required to be true in case of logical or operator and the third operator and the third operator is logical not this is noted by this symbol. Suppose a is a number and not a suppose this is the truth table for logical not suppose a is 0 then if only reverse the number it will be 1 suppose a is true it will reverse this like this it will be false this is the logical not operator that is logical not produces a 0 if the expression evaluates to a non-zero value and produces a 1 if the expression produces a 0 value. Now I am coming to assignment operators assignment operators I have already told that the single equal sign is denoted is used for assignment operator and double equal sign is used for equal to sign assignment operator is used to assign a value to a variable suppose I want to assign a value to a variable this is the assignment operator and this is the equal to operator suppose I want to assign a value to a variable suppose I have declared a variable like this integer a suppose a equal to 20 that means 20 is assigned to a the value 20 is assigned to a this variable stores the value 20 similarly suppose I have in the next step when I have written 40 that means 40 is assigned to new value of a is 40 then 40 is assigned to a this is the use of assignment operator the assignment operator equal to and the equality of operator double equal to are definitely distinctly different the assignment operator is used to assign a value to a variable whereas the equality operator is used to determine if the two expression have the same value there are some short hand assignment operators that means we can write a single statement in different way let me show this in a tabular format here a equal to a plus 1 that means 1 is added to a and this value is assigned to the variable a this can be written as a plus equal to 1 in the next statement a equal to a minus 1 is same as a minus equal 1 in the same way the last statement a equal to a mod b in this statement it can be written as a mod equal to b these are shortcut operators assignment operators we can write this statement in a different way like this now let me discuss what is conditional operator conditional operator is a tarnary operator because it uses three operands the syntax of writing a conditional operator is like this let me write the syntax expression 1 expression 2 expression 3 and is this combination of this two statement this is the symbol of conditional operator this is the syntax if this expression or condition is true if this condition is true it will result this way and if this condition is false it will give this way in this way the this conditional operator works here three operands are used this expression and this expression and this expression so it is known as tarnary operator because there are three operands let me take an example a equal to 10 b equal to 15 that means 10 is assigned to a and 15 is assigned to b then in the next statement x equal to a greater than b I have used this question mark then a then colon then b and then after that a semicolon here value of b will be assigned to x because b is 15 and a is 10 a greater than b is false because 10 is less than 15 so it will give the third part that means expression 3 and which is here b the value 15 will be the output of this two statement I have written one example to describe the use of conditional operator here in this program it will display whether the user is eligible for 4 or not if the age is greater than equal to 18 then the user will be eligible for 4 otherwise you will not be able to 4 for this program I have written this main part I have declared first one a variable integer is in this output statement enter your age in years when the user enters his age with the help of this input statement scan f then age will be stored in this variable age after that a conditional statement operator statement is used here in this statement if age is greater than equal to 18 then first symbol is used question mark print f you can vote then I have used one colon print print f you cannot vote if this condition a is greater than equal to 18 if this condition is true then the first part you can vote will be displayed if this condition is false then the second part you cannot vote will be displayed if the user enters suppose 24 as an input then the first statement you can vote will be the output of this program if the he enters suppose 15 that means his age is 15 then you cannot vote will be displayed this is simple program for determining whether a person is eligible for 4 or not in the next class I will discuss unary operator binary operator then bitwise operator comma operator and size of operator after that I will discuss one important topic which is precision and associativity operator thank you


August is hot and so are the savings at Appalachian Wireless where all smartphones are 50% off. Even the 64, 128 and 256 gig models, two-year agreement required, better service, bigger savings. That's today's Appalachian Wireless and East Kentucky Network Company. Today marks the one-year anniversary that the arm drop guy Kent Rose passed away from complications of lung cancer. Kent had a passion for drag racing but it did not compare to his drive to make a positive impact on the children of this region, a drive that was with him until the very end. For as long as I've known him, he's always had a focus on kids and families. Even in his dying days he plotted and planned on ways to help. He talked hours and hours on potential events and benefits and areas that could be impacted with the proper planning. I remember a line that he used to say and post all the time. No matter where he went we'd run into so many kids that were less fortunate and he just wanted to give and do so much for him and he would always post. They had nothing that they gave me everything. Kent's insatiable drive to help the children and families of this area lives on today through the non-profit Kent Rose Foundation. The first step is a scholarship project. Kent wanted for years to do scholarships for kids and he wanted to do it on more of a vocational technical school level to make it more achievable. So we're working now to set up their criteria and that'll be announced soon. But in doing that we're also working with employers to get internships. So we're hoping not only to provide a scholarship but to find jobs for those recipients. For more information on the Kent Rose Foundation visit them at the web address listed on your screen. Reporting from Prestonburg I'm Sean Allen for EKB News.


So I'm here with Chris Ryder, I'm here to pick show Chris, it's from 819 and he's working on OPV. Chris tell us what it is. So we've got some demonstrators in the showcase here where we're showcasing some of the things we're doing in the Internet of Things. In my hand here I'm holding a PV powered iBeacon. So we've got a small area of PV here, just a little demo, we've got some electronics on the back. I've got an app on my phone, it's transmitting some information from the iBeacon to the phone and it can figure out how far the phone is away from the iBeacon. We've got another little demo down here at the bottom, we're harvesting some power, we charge up a capacitor and then when we've got enough we make the LED lights flash. That's this one here, we've got a temperature sensor at the back here and then we have another module here which you can see is a different colour and the reason for that is because it's sensitive to infrared light as well as visible light so some of our customers have been asking for things with infrared sensitivity. So we've got a range of different things we can do, we can customise products for a whole variety of different applications. So what do you see is the main initial applications, which are you proud to do? So we're doing customer dependents. Very much so, so at the moment we're working with lead customers who've got serious big applications which require the things that we can do well. So some element of customisation, flexibility, light weight, robustness, all that kind of thing. Two big areas, one is off grid which is what we've always believed, so portable power and the other one which we've been learning around for the last couple of years really is that there's a lot of opportunity on indoor energy harvesting, internet of things, wireless sensors all that. Great, thanks Chris. You're welcome. Cheers. Cheers.


Welcome back to this channel, we come back again and smx from the next creation. Remember we are still looking at employment laws, we are looking at regulations of the laws in the private sector and we are looking at what does the UAE lebalo says in the private sector, what are some of those articles you definitely know as an individual working in the UAE either working in Abu Dhabi, Dubai or Indonesia in any other Emirates that make up Dubai, what should you know and in today's video we are going to look at yet another article and that is article 27 of the UAE. What does article 27 of the UAE, it boils any company or any individual to make women work at night, women as according to the UAE or lebalo or any other department, women are not supposed to work at night, women are not supposed to work at night, between the hours of 10 p.m. to hours of 7 a.m. remember that they either remember that as according according to the article or according to the article of 27 the UAE lebalo no woman should work at night between 10 p.m. to 7 a.m. remember only if a woman is in what you call an executive role or what you call a mangerio, mangerio role or technical role or a woman who works in an industry such as a healthy sector is only person that will be mandated to move at night or to move anywhere at a given time so definitely you definitely know what we are talking about article 27, we are talking about that article where women are not allowed to work or women are not allowed to work at night remember these will also come to what you call their safety and most of these countries are indulging almost are indulging in such kind of of targets to make sure that they protect their employees. Thank you so much for coming back to Siano by the way it's your first time to come across Siano hit that notification bell. It's mixed from the mixed questions here again


Morning traders, Patrick Menlo here with another tip-nail chart. I want to draw your attention this morning to potential couple of opportunities developing in the sterling dollar on the hourly timeframe. Got some projected channels in play here. What I'm looking for now is the pullback we're seeing to find support into this 3650, 3640 area, 3650 being the symmetry swing versus the last correction and the 3640 being the projected daily range sport. But for this to emerge there I want to see a close back through the five-period VWAP to set long positions targeting a test of the 138 area which is the projected weekly range resistance and I'll be looking to set short positions with bearish reversal patterns in this zone to target and move back to 136. As always traders, plan the trades, trade the plan the most importantly, manage your risk. Until next time, thanks very much.


Actor Krithi Sanon has co-founded the startup The Tribe along with Anushka Nandani, Karan Sani and Robin Bale. The company offers virtual products like workshops and diet specific plans. Now on Twitter, the actor said, 8 years ago I started my journey as an actor in the Hindi film industry with the help of people who believed in me and gave me wings to fly. Today, 8 years later, exactly on the same day, I am thrilled to announce my journey as an entrepreneur as we launch our passion project The Tribe. She also gave more details about the project on Instagram. She said that Robin, Karan and Anushka became a huge part of this journey of mine and made me realize that to stay fit, all you need is motivation, the right guidance and someone who can make workouts fun for you no matter where you are.


Why don't we start? Well, there's absolutely no doubt that the UK will do whatever the US wants. If you go back to the days of... We've had lots of prime ministers recently, but if you go back to the days of David Cameron, the idea then was a golden era of relations between the UK and China. Well, that golden era is now long gone. Britain caved into American pressure over Huawei. When I say caved in, I mean, that's a pejorative phrase. And I think in the end, probably the security people in the UK were happy to have their arms twisted. But I mean, basically the UK is always going to follow the US lead. And I think that is also true essentially of all the countries in NATO. I mean, the thing, if you look at the China, the People's Republic and the USA, the fact is that the US has lots of allies, but China has lots of trade partners. I was shocked the other day when Carl Bilt pointed out that there are only 20 countries in the UN who name the US as their number one trading partner. So essentially that means Canada, Mexico, a few Caribbean islands and so on. Whereas if you take the reverse, you take how many countries name China as a lead trading partner, that's at least 120. So if you were to look at this sort of rivalry as a potential conflict, then you're tempted to use the phrase, a might is right. Well, how do you define might? Is it economic pressure, economic links, or is it military pressure, military links? Maybe it's something that we can get involved in later. But I think what lies behind your question, Douglas, is if push comes to shove, which way will countries, what choice will countries make? Well, of course, none of the countries want to have that choice. They want to avoid it. And I think common sense should indicate that the choice never has to be made. But that's what we're saying now with the benefit of common sense. Common sense doesn't always work. You have First World War, Second World War, and so on. I think that if you look around the world at the moment, if you take NATO out and say, OK, all the NATO members will follow an American lead, if you look at Africa, there are now something like 10,000 Chinese firms operating in Africa. You've got the Chinese military base in Djibouti. You've got potential bases also. I think China now is developing something like 50 different ports in Africa. That's not necessarily a bad thing. If you take the whole BRI initiative, which is obviously not just Africa, it's Europe, it's Central Asia, and so on, that really does bring real influence to bear. The downside of that, of course, is that you get a sort of debt imperialism. If you take Sri Lanka, for example, there, the Rajapaksa government went into some dodgy deal and suffered for it. But it means that the main port is now basically taken over by China. If you take Greece, where I was in Athens last week, I mean, Pyreas, one of the best ports in Europe, is now Chinese-owned, effectively, and works very, very efficiently, very effectively. So one shouldn't see this in a Manichean way. I mean, there are reasons why countries should accept largesse from China. But if the largesse also does come with some strings attached. I thought it was interesting that Xi Jinping is maybe even now still in Saudi Arabia. I mean, they may be leaving tonight, I'm not sure when. Perhaps he's waiting for the soccer matches to finish in Qatar. But I mean, Xi Jinping is making good friends with Saudi Arabia and really with the whole Gulf Cooperation Council countries. Remember that Saudi Arabia has been a faithful American ally really since the foundation in 1932. So we're talking 90 years. Now that's all up for grabs. I don't want to rub it on too much, but I would think that Africa really does not want to make this choice. And I don't think it really has to. It can be independent. A much more difficult choice, I think, is in Southeast Asia and South Asia. I mean, Pakistan is, I think, really in hawk to China thanks to the CPC, the China-Pakistan Economic Corridor. And if you take the countries of Southeast Asia, they all depend on China for their trading links, their economic growth. The challenge will be over Taiwan and what may happen there. I'm actually fairly optimistic. I don't think Xi Jinping is a madman, nor incidentally do I think Vladimir Putin is a madman. But you can't really meditate too much against what can happen when people make decisions which then lead to other consequences. I think we, I'm talking when I say we, I sort of mean West here, I think we were lulled into complacency in the era of Deng Xiaoping. And that carried on with Jiang Zemin and Hu Jintao. I think with Xi, it's a different ball game and we don't really know how to assess him, how to treat him. And I think that means that the possibility of miscalculation does exist. A final thought, if there were a war, remember that American military really is battle-hardened. So if there were a war between China and the States, regardless of who is on what side, I suspect America would win. But that's sort of a catastrophic concept which I don't think is going to happen. But, you know, one lesson I think that Xi has taken from the UK war is that the American military and NATO in general, but especially the American military, is really very, very good. And I suspect that if you look at the Chinese military, even though it has invested enormous amount into modernizing the military, the Navy is supposedly now bigger than America's Navy. Nonetheless, it hasn't done, it doesn't have much battle experience and what it's had has been pretty poor, for example, in Vietnam. So let me leave it there. Thank you, John. I think there are a number of things I'd like to probe on that. Is China going to be everybody's leading trade partner forever? Is the disposition of forces the way you've described it or has it been changing? Is the debt policy of China undergoing various changes as we heard this morning in other panels?


t jr that is dope i'd say you can bag that and probably the petty so far right what do you think yeah i'm not yeah maybe not the junior for sure junior for sure we've got uh gray gaulding 26 of 49 gray gaulding on the base that is a uh race use sheet metal 72 and 99 chris busher 72 of 99 we've got seven of 25 driver hats chris busher driver hats seven to 25 chris busher this is dope dude race use fire suit 76 and 99 dale earnhardt jr nice now i think they're a little bit more than that i would say shorts there we go base auto ward burton we were talking about 22 caterpillar car there he is is that jeff he said jeff burton's brother brother brother gotcha older brother ward burton base auto midnight shadow box signatures justin hailey nice 23 of 99 justin hailey on the third shadow box we've hit now is it yeah i think so was the gillian one yeah and then 63 of 99 kyle bush on the auto hey three really good autos to end the three boxes so far good stuff and good luck on that one kyle bush what do you say i'm on the right oh gotcha right onto the next pack got a redemption could be nasty uh william byron that is 36 of 49 dope this next one's really dope on the base pretty much i would say greg yes this is sick man 41 and 99 ricky stenhouse jr on the sheet metal names patch three color they turn up 500 winner yes sir it's past year ricky stenhouse jr got race used sheet metal uh chase brisco 61 of 99 61 99 chase brisco chase elliot 5 and 25 driver hats chase elliot that's a solid one too yeah we've got a signatures 28 to 75 michael mcdowell michael mcdowell 28 of 75 on the signatures that is going to be door number signatures number 43 is eric jones 43 of 43 i like that's number to the car number that's sick door number 43 of 43 eric jones that's technically a 101 right there because it's the car number 43 of 43 which is really cool so nice one there and then signature uh redemption prime signatures hollow silver william byron william byron on the redemption good stuff all right we're halfway through the case ladies and gents 24 of 64 richard petty that's sick i haven't seen this insert yet with the number 43 the super bird or the dodge charger detainee no he drove a super uh super bird right that or a uh a barracuda one or the other hello candler nice race used sheet metal bubble wallace 22 and 25 nice oh can we get chris out of here please goodbye chris i'd like i'd like uh seattle seahawks head coach mike michael mcdonnell signature ha ha ha well you're gonna get nothing chris i'm gonna give you three spots away we've got um that is joey legato 71 or 79 of 99 on the race use tires that's dope that is gonna be race use fire soup one of one alex bowman that's dope on the tag could lock on that everybody that's dope so sick one of one alex bowman race use tag let's go so sick man how about this one right here our guy rusty wallace on the auto rusty wallace congrats and good luck on that oh it's so awesome candler it's so fire man rusty wallace we've got a sheet metal signatures uh sam meyer 10 of 25 he's a good he's a really good yeah is it meyer meyer it's meyer sam meyer meyer meyer oh it's meyer sam meyer 10 of 25 oh he raises for junior steam oh that's pretty cool and then the guy on the it's the guy on the thumbnail 63 and 99 carl edwards the backflip baby 63 and 99 carl edwards hell yeah dude that was wild craig here goes i wonder if you could hit a carl edwards you still love to flip right as we had the carl edwards that's insane got a redemption everybody all right starting off with a base that is uh jimmy johnson 10 of 10 not bad nice 10 of 10 jimmy johnson that is going to be ricky stenhouse junior 55 of 99 race use fire soup race use sheet metal tyler retic 2 of 25 showcase swatches brad keselowski 29 of 99 that is going to be race used higher that's race used higher on the acetate that's actually really clean brad keselowski that's really sick in the showcase swatches we've got a tony brenger 21 of 75 on the auto tony brenger brenger thank you they have really good autos for most part let's go my guy that is eight of 10 greg biffle so sick man greg biffle eight of 10 national guard 16 and then we've got a redemption prime signatures red kyle larson oh nice one there that's nice that's really nice that's nice one of i would say the best drivers right now right yeah remember austin dillon is he still race yeah he's just not very good not very good did he drive number three yeah a lot of people don't like it i can imagine a lot of people don't like that yeah that's a whole other thing moving on big biff love great biffle man have a little diecast of the 16 national card uh national guard car i gotta do that i gotta take a picture and i go home next time with all my NAS cards like toys and uh then we can just go through them and like laugh at all the the crazy names that's gonna be martin truex jr 34 of 49 on the base 34 49 34 yeah 49 got raised race used sheet metal uh col custer two of 99 custer baby a bunch of patches on that i don't think ricky craven is in this that guy was a stud he drove 30 that's who i was thinking of for 25 25 got ricky craven well he drove 32 right the tide 32 and he embraced um hurt bush for like it was like one of the closest finishes ever yeah whoa that's insane race use tire christopher bell 61 and 99 that's a big name too yeah that's a big yeah that's massive dude yes christy bell tire holy cow man one of one jumbo patch ross chastain s5 manufacturer certified that is so awesome one of one our second one of one man he is a he's good too he's a big ross chastain holy hell man that's so sick he's a big that is disgusting yeah who's uh somebody else said the wall rider yeah he did do that this one's dope we were just talking about him too ryan blaney ryan blaney on the base auto i was going to say it's gotta yeah imagine a ass dude uh we've got another one of the die cut signatures that is going to be 21 of 50 at daniel suarez that's so dope too dude daniel suarez on the die cut still 360 yeah it's gonna have to be 60 and sticking out i know that happened a while ago with the pumps we pulled the dominy wilkins pump and how about 13 of 50 bill elliot on the auto the red prime auto congrats and good luck on that one they banned that i remember seeing that they did ban it bill elliot 13 after he did it he said no more bill elliot all right last box here everybody this has been a really good case two one-to-ones in this game which is kind of ridiculous in my opinion what they banned the wall rider like why got a redemption that is hall of fame martin martin 24 or 49 the guy the boy right there mark martin 24 or 49 we've got a chase brisco 22 of 99 uh racy was sheet metal i used to drive bobby labani in the nascar game hell yeah candler he's in this he's gotten auto in this i think i have not pulled that he was known for the joe gives 18 yes race use fire suit tyler retic 95 of 99 wow another nice one dude that's sick i see it that's dope they say the last name castle this one there we got another prime jumbo patch of landon castle 22 of 24 w it's a w card right there w card w card w card uh next up base auto of natalie decker uh you got you i think you got a candler decker base auto next up again big biff let's go baby uh 750 is that actually the red m&m what no no i want to be the m&m right now no castle races i think in the uh prime signatures hollow gold number to 10 ty gibbs on the redemption that's a nice one too that's a nice one number to use a rookie last year you did really well in xfinity ty gibbs is he related to joe yeah he's the grandson grandson of joe gibbs he was the son of oh he's the he passed away the uh the son he the the dad uh he was like a coach of the red washington i think too forget his name though something gibbs yeah i swung that all right we'll do a little bit of uh editing here all right so the pet the richard petty is the best base by a mile that's gotta go with what you think the lowest hit is okay zane smith's coming up he's had some talks of getting some xfinity rides and stuff i would probably hold ty gibbs is nasty though ty gibbs i would think is probably a um a contender for the championships i'm gonna put the bowman with the uh bullet joy ty relic kyle larson with the Alex bowman suit relic again i'm just really going with the stuff number to 99 outside of the like under earnhardt i wouldn't put it anything with i would do the busher sheet metal with uh with the gallding or the petty galling galling uh what number you're looking for the worst one you theoretically whatever it would be for just for the pet because the petty is the nicest for sure probably cold custer is with the petty all right that with the petty the cold custer oops yeah joe gibbs nfl yeah yeah joe gibbs thank you thank you joe gibbs yes no but he had a son that had ty gibbs i forget his name he passed away this past year he raced a little bit the Byron i'll put with the um the briscoe sheet metal cool jimmy johnson we'll go with the that's freaking awesome which one the chastain chastain's disgusting he's from around he's from is he really he's close to where i'm from truex and then who is he really a watermelon farmer that's i know he's watermelon so sick all right we got them all everybody those guys are they rookies the two of them prisen uh was it bonciniere prisen who bonciniere bon what justin bon sig nore where uh where chris said it my why in chat because it wasn't from this it was from oh oh i don't know who bonciniere is brian priest he was he was up and down from the cup and xfinity like he's on the fringe that makes sense all right we got 48 participants everybody we got 48 hits and hit uh combos now let's roll the dice we're going seven times one two three four five six and seven john s down to christopher j seven times on all your hits everybody one two three four five seven right yep uh six and seven the chase briscoe sheet metal and william byron base down to the chris busher sheet metal and uh gray galling base all right i got john s with the briscoe and william byron uh robert r with the um uh cori la joy jason w ricky stenhouse junior sheet metal and rickard petty auto 99 jake obama to daniel suarez auto uh andrea natalie decker auto matt h with the ricky stenhouse junior fire suit relic john s tyler retic fire suit and martin truex junior base uh lucas with the ryan newman hat relic josh h tyler retic sheet metal 25 dogless b with the alex bowman suit relic in the uh kyle arson base 10 not bad matthew w with the chastain one-on-one fire suit nice uh snell with the tie gibbs redemption lucas b with the cori la joy tyer relic and the alex bowman base brandon are with the greg biffle to 10 felix and with the eric jones auto 243 chris receive with the riley herb sheet metal uh erin o with the ryan blaney auto davam kyle bush auto to 99 chris receive with the ryan priest shadowbox to 50 matthew w chris for bill tyer relic and jimmy johnson base to 10 uh erin o with the chase briscoe sheet metal and mark martin base to 49 joe h with the rusty wallace brandon are carl edwards to 99 uh snell with the jimmy johnson tyer relic uh nice there you go shorts with the kyle arson redemption uh chris s with the uh dale junior suit relic to 99 uh we've got felix n with the sim mayor patch auto to 25 shane c with the chris busher hat relic uh robert r with alex bowman fire suit one-on-one congrats bobby brandon are with the bill elliot auto to 50 scott h eric jones hat relic matt h dale jr auto to 75 lucas with the keselowski showcase swatches uh chris s with the jerry cook base auto dan c with the chase elliot hat relic uh felix edward burton auto um john s with the tony bride injure auto to 75 greg t with the william byron auto redemption chris c with the legano tyer relic snell with the kohl custer and the ritchard petty base to 64 very solid john s justin hailey uh shadowbox auto joe and the michael mcdowell auto to 75 greg t with the bubble wallace sheet metal and chris verge with the todd gillland patch auto joe h with the land and castle jumbo relic zachary s with or snell with uh big biff auto to 50 and chris verge with the chris busher sheet metal 299 and the gary gaulding base auto 299 uh that will do it for the break everybody thanks again to the field up next is person yes kyle arson is very good shorts very good very good shorts one in championship in 21 championship contender jacob and ryan both picking up spots for tomorrow probably the best driver and andrew here's your guys is linked to the results and c dog grease let's go hell yeah enough enough hit the dill junior auto let's go enough said go that's nasty hell yeah baby i need to get one for my collection man need to get one so bad dill junior yeah i want to start collecting i picked up uh i said i think i sent you i picked up two jeff burton autos a while back probably six months ago but i thought they were dope elliott sadler that's another guy i've got enough are you matthew or no are you not matthew oh you're matt h matt h that's my bad matt each got you got you got you let's say because the other matthew hit the um hit the chastain i was like damn if you had the dill junior and the chastain that'd have been nuts yeah i'm gonna get the anime for you don't worry uh the junior yeah yeah for sure yeah we'll get the anime i appreciate that uh we'll still send it to you uh but it's just because we kind of have to uh to to properly like um um prime signature is red i'm not sure what that is on the checklist i think it's the 50 is it my guess would be the 50 because that's what the biffle is the 50 and it's also the red and then the gold would be the 10 i believe it'll be uh to um that would make sense to 50 let me grab the first batch of personals here again i'm not gonna get to everybody tonight i apologize but i probably will not no no recap on it because jake has to type everything in um so i don't do it i don't do a read i don't do a recap on any of the random hit styles i didn't get to apologize man no you're good no it's not your fault too i'm currently trying to get them all sleep in tabloid yeah there's not really like a very efficient way to do that to be honest all right be right back everybody i'm gonna send you guys through a commercial number three of five five taj bradley frozen fracter that is an expose rookie jordan walker cardinals number to 50 nice sp there we go oh good few boxes here the yanks one of one green oswald foradza nice congrats on that one yankies going to uh if i could find them that would be sick uh daniel c congrats daniel good stuff dude that's awesome big poppy jersey autograph five of ten rod red socks heck yeah boss and love this one that's greg m greg has a lot of the work teases now too and colas josh chesum and dual auto mets to 15 bread baby david right heck yeah let's see a duel on card auto already from brian g and the mets we're gonna get this one in a mag that's pretty here everybody randy and rosa reina one of one logo man edward s in the rays come on baby jake just missed it wow dude one of one randy rakes i'm sure we're for the red sox there he is blue refractor rookie auto holy yeah dude maricio in seattle 68 of 150 and a red one of one corbin carol rookie autograph a monster oh my god christ dude one of green green david ortee two that he's pulled oh two that he's pulled um game use patch card red sox that's a second mama mia that hurts kershaw and hosay out to bay one of one go into the astros one of last teams taken momentous material jumbo patch auto wow what a box man fire i'd say pumpkin pie can eat the most of sweet potato pies just give me a bunch of cool it book it's the atelier autograph booked at 25 of ronald acuna jr christopher w with the braves refractor protector to 10 and it is a gold and it is adley rutchman oh my god what of 10 baltimore wow dude josh will are with a big time adley there we go up won't stop kind of 30 bar and bucks thing and then rpa uh four of 10 gunner henderson my gosh man three colored game used rpa gunner henderson all right you guys ready for the one-on-one booklet ready ready both uh whoa one of one kyle schwarber dude what a patch on that i'm assuming that's from the second eye because that's the loop of the l that's a loop loop of the second l with the star from the eye that's so nasty oh my god man wow david orteez tristan cost is dual autograph boston 14 of 15 there we go yeah michael c yep vaughn i am uh we're going through the same emotions currently heart beating faster breathe oh my god look at that on card and everything come on man that's beautiful uh i don't uh whoa oh my god yeah 28 of 75 shohei otadi that's huge finest intimidators auto going to the al west thomas gay that's huge holy hell man that is awesome you get like that is a rookie taj bradley frozen fractor number three of five three of five taj bradley frozen fractor that is an expose rookie jordan walker cardinals number 250 nice sp there we go good few boxes here the inks one of one green oswald foradza nice congrats on that one yankies going to uh if i could find them that would be sick uh daniel c congrats daniel good stuff dude that's awesome big poppy jersey autograph five of ten rod red socks heck yeah boss and love this one that's greg m greg has a lot of door teases now too and colas josh chisum and dual auto mets to 15 bread baby david right heck yeah let's see a dual on card auto already for brian g and the mets where you get this one in a mag that's pretty here everybody brandy arosa reina one of one logoman edward s in the rays come on baby jake just missed it wow dude one of one randy rakes i'm sure before the red sox there is blue refractor rookie out of who yeah dude maricio is seattle in a red one of one all right sticky i'm gonna stay here sticky oh good nice did it did finish any fun nice nice does that look okay ah looks good yeah that's fine all right trip it sealed rocky's gone thank you to mr erin says well good luck here evan let's do it buddy going on everyone sam here with late in sports cards we've been one box of 23 phoenix football hobby uh for evan watch good luck here evan let's do it buddy phoenix phoenix phoenix edit josh jacob's down gino smith purple to 99 and jk davids playing bebop playing bebop dealing carter davan arching to 199 on the rookie jumbo jersey azea foskey or no not azea foskey kendre miller teal and tony dorset silvers rice young rice young fired up auto derrick car that is six of 20 on the orange auto for the saints jordan adison what i guess it's gonna go in two pages that's fine silver to uh pink jimmy g to 175 and base truly below two tirey kill to at 175 and derrick car playing with fire nick chubb tony dorsett to at 150 hot rods of monro all orange dalton concave to 99 and rake one slaba canine red adin o'connell 250 erin junes color verse to monro st brown for the lions fire nice john slifard rookie to 50 and rice young red pink del silver fire our uh lava to 175 trevor lorns and avante smith it's a patch of some sort uh new schoonmaker three of ten nice rpa for the cowboys i like the entire rainbow of this basically at this point cool shield yeah it's a nice one there congrats evan good stuff buddy and rice young rookie that's where let's do it for your break there mr evan thanks again for the sport buddy get right out to my man you got three art of sport solos up now which is good though awesome awesome make sure to drive on the right side of the road when you get home jake hey appreciate that vaughn i'll appreciate you looking out for me man appreciate that eight ton but seriously vaughn hope you have a good one too man thanks for hanging out yeah have a good one vaughn this one do you want your personal to go tomorrow vaughn or do you want it to go tonight it's up to you do you want to watch it because you ordered them to get ripped right justin didn't have a chance to go tonight oh i mean you're gonna go in a little bit do you want to do you want to do it tomorrow or do you want me to do it tonight it's up to you man up to you it was okay never mind i'm not leaving i'm not leaving all right good luck here justin going on everyone sam here with late sports cards we're in two boxes of 23 leaf art of sport solo edition for justin s so good luck here justin here we go so am i vaughn so am i consignment time shoot us an email shorts all right starting off with a john mackin row that's dope 24 to 25 well tennis action there 24 of 25 game used or match used i should say then all into the second that is nice anthony edwards eight of nine yeah eight of nine for the teawolves good stuff there justin congrats buddy i'll do it for your break there justin thanks again for the sport buddy get him right out to my man youth a lot uh art of sport merlin and late good luck try youth a lot here we go buddy going on everyone sam here with late sports cards there's been two i don't know three boxes for chai toa l we got one leaf art of sport solo 123 merlin and 123 bowman university chrome delight so start with the merlin good luck everybody yeah shoot us an email shorts shoot us an email about that shoot us an email uh and so for nanda it's the 150 on the wave auto and i start there gondosi olympic anthony osilva 350 las ro martinez las ro martinez refractor arnaud colomondo go to gotpo fagioli refractor root fagioli fagioli give me the formula that there you go cabryl marinelli where they like they're like 25 point uh like 25 point they give me between what a 35 and 55 yeah alex larry that's uh matia sule juventus on the vintage merlin lataro martinez luke modric so 299 desredoia ranae Luis figo he's just out of me a young uo for Celtic on the refractor root uh luke sucic and green to 99 and tonio silva for benfica is bowman u chrome uh university of delight to 299 to 399 elijah martin f a 299 rj jones 399 jeremy fears and a 99 jared mccain first refractors of jeremy fears rice hopkins taryn shannon ronnie james on the sharpshoes got boppa miller first base auto get some church pants there it is first base auto jordan dingle for jane johns and riley google to 250 for the flora gates and then one leaf art of sport solo edition deluxe shahid oh really george kirby's birthday birthday george kirby birthday george kirby happy birthday man hope you have a good year you have a solid year right now that is chris weber one of 12 um on the game use jerseys nice one there shahid what part of the fab five very nice that was a great break there mr shahid what thanks again for the sport getting right out to buddy really hope that becomes a thing but they go to the race there's no way see i don't do that that was terrible that's tom c up next icons so weird when we flip over to uh what's it called um no 3000 uh to uh flip over to 300 000s for the orders because they're at 200 000 right now you guys are all psychos i don't see as a crowd i it's a real crowd good luck here tom let's do a buddy going on every old buddy sam here with lint sports cars we're in one box of 23 tops diamond icons baseball hobby uh four tom c good luck tom let's do some icons baby 23 see a big cut come out of here big cuts that gibson was probably the nicest cut up so far something thick in here it's a really thick card we had last time it was a mic shot oh that's right jumbo yeah like eaters yeah that was dope i remember all right starting off 7 of 15 big poppy not too shabby there's 7 of 15 david orteez uh yes yes it will uh shorts that is 9 of 25 uh chipper jones on the diamond auto have a go in shorts see your shorts three of 25 god mark maguire that is one of 10 on the silver ink auto big mac j ram that is three of 10 for the guardians i've seen him in this i know yeah not a ton of jay ram interesting i've seen a couple of beaver there's 10 of 25 trey turner i don't think i've seen him too he was perfect perfect decent we've got andy pettit that is five of 10 for the inks purple ink andy pettit paul goldschmidt there we go one of one on the gold diamond auto congrats on that one there uh tom very nice tom one of one paul goldschmidt continues to hit icons man oh yeah just continues to hit and icons eight of 10 is that's sick um andre dawson eight of 10 the hawk that's a pretty cool name too awesome this one's dope give it to me one of nine salvador perez on the cleat relic jumbo cleat relic salve congrats on that salvador perez and then we're gonna end it pretty solid here as well that is going to be five and 25 mic trout okay mic trout congrats on that one there tom very good buddy that'll do that'll do a fair break there tom thanks as always for the sport buddy get him right out to my man another trout like tom's collect yep goodness man how much are his icons like four grand or something three three it's over three grand three something they're over four i think they're like three some three six maybe i know salve going to dh roll not super shocking right yeah i'm jay melendos man all right vaughnster with uh some stadium club this man yeah there's some good hits right there's right the show for show good luck vaughnathan going on everyone sam here with late sports cards have been three boxes of 23 top stadium club baseball for vaughn beat good luck here vaughn i appreciate you staying in here claudio i'm glad you're enjoying the show i love it claudio that's the you know that's what we're here for riley green oversized box toppers riley green if you haven't liked the stream yeah make sure to drop a like subscribe if you haven't you have not already for sure you are enjoying it be on the lookout for future breaks tomorrow oh yeah chrome of brett baby my giant toppers are all the way over here now the tox awesome love it yo hall frank thomas redfoil the chanager cow michael rookie auto nice one there for the uh parts got some on nick prado and chris sale logano hoppy yep they definitely yeah photos and these are awesome man gladi jr you say gladi jr oh is it senior senior mike trout senior sorry dude my bad my bad man messing with you refractor of brian bao bonds offended nice one there that is a james outman dave winfield redfoil uh brex harper andre mccutcheon redfoils i could see it bao sion that'd be dope i wouldn't hate that to be honest lute gary i wouldn't mind it either he's actually pretty good i'd fail hate that he's a red sock why do i have a soft spot for a red socks picture 199 that's kind of shocking to be honest park is upon the school and all the red sox fans are pretty good ready to res nice i was one peraza rookie order for the yankees yeah let's go terrible we want red sox only now we want yankees yeah we want red sox only that is brice harper right now i keep pulling on the Yankees stuff yeah boo boo this man boo and chrome of shane beaver it's a swing and a miss right there look at that that's a swing and a hit johnny bench swing a bomb right there right out the short nice a bomb right there really nice dude really got a hold of that one black foil of one sir brian hayes redfoil the redemption redfoil keith ornandez face card autograph of ronald akunya jr there we go vaughn oh he said almost as many yankees on their ir and may dude okay well guess you're not getting this then buddy sorry really nice one though vaughn congrats i guess we can mag that one red foil nice let's go vaughn hell yeah vaughn we're gonna mag that 40 of man getting palmer black foil i have not seen much lane pulled the one-on-one that's like all we've seen of akunya each euro triumph ritz yeah nice one there vaughn congrats buddy kuna juna yeah akuna juna hey red foil uh about josh smith red foil ir judge arson judge arson judge heading to the giants so we're gonna miss hayman you bought four giants fans we got them trolled twice and matt swarmer jake's boy all right last box here one pretty solid uh second one for sure that is a pete lanzo with bobby witt g1 bay black foil i know arson judge dude so stupid i gotta be first i gotta be first i gotta be first i gotta be first i gotta be first yeah and then you blew it absolutely blew it dude really really blew that does he not proofread no really not team team asa takayoshita congrats vaughn short front of a red sock very nice dude you can pull red socks i guess so hell yeah well i pulled them he had the red socks in a uh case of this the other day i pulled him a paedro auto really don't pay really really cool paedro um insert auto was a braille ezekiel doran rookie auto for the uh rangers technically i did pulled one another Yankee with him because he was a Yankee and we traded him for joey gala yeah i like how they made beam teams sps as well posey and oswaldo cabrera red foils red furls one soto triumph ritz 79 o peachy that's a big one garrick coal on their factor yeah that's a young garrick coal right there sigh young drew waters thank god you pulled the red sock ryan sandberg rice terrain orange rookie to 199 it's an orangutan so alvarez christian yellich that was lame that was that lame that's fire yeah i would say you'd probably make money on it uh claudia if you sold the case yeah got it than india vaughn come on man you know it was good you know it was good you should say it's an orangutan instead of an orangutan like that it's just then it just now uh charlie glavin george curby happy birthday happy birthday whoo base and base that'll do if you break vaughn thanks again for the support buddy good amount to my rain to rain here you go does it work now really thank you hon just please help me all right we'll grab some more i'll be right back 68 of 150 bang a rang and a red one of one corbin carol rookie autograph a monster that's you oh my god chris dude one of green green patch card red socks that's a second mama mia kershaw and jose al-tube one of one go into the astros one of last teams taken momentous material jumbo patch auto wow what a box man fire i'd say pumpkin pie can eat the most sweet potato pies just give me a bunch of cool it and pumpkin pie and i'm good book it's the atelier autograph booked at 25 of ronald acunia jr christopher w with the braves that's oh refractor protector to 10 and it is a gold and it is adley rutchman oh my god one of 10 baltimore how do josh will are with a big time adley there we go up won't stop had a 30 bar and bucks thing and then rpa uh four of 10 gunner henderson my gosh man three colored game used rpa gunner henderson all right you guys ready for the one-on-one booklet ready ready bofa whoa one kyle schwarber dude what a patch on that i'm assuming that's from the second eye because that's the loop of the l that's a loop loop of the second l with the star from the eye that's so nasty oh my god man wow david orteez tristan cost is dual autograph there we go 14 of 15 there we go yee haw michael c yep vaughn i am uh we're going to the same emotions currently heart beating faster breathe oh my god look at that on card and everything come on man that's beautiful oh my god yeah 28 of 70 games true yeah true we're not trash but over but all right everybody good luck jeffrey i don't it does say lean on it i don't know if we sell them i don't know if we can to be honest i don't know if that's like theoretically legal good luck here jeffrey and everyone sam here with late in sports guards been two boxes of 23 bowman draught baseball sapphire edition and won 23 prism football for jeffrey h good luck here jeffrey 23 bowman draught sapphire here we go start that step shaw back for them i are they on i don't think so anderson mattshaw yellow brady smith to 75 the doors so i'll stand jacob wilson yeah these are nice i like this stuff marcus brown orange adrian santana for the raise the 25 all right well it's christian napsick it's a hundred brand thing i can imagine brock vradenberg to 199 first auto for the marlins we got jeffrey not too shabby montgomery jace berofen yellow eric paton t to 75 for the brew crew gravy and based gold connor burns the 50 nice one there on the gold sapphire first sava cool and jake cunningham yellow sabon sabios first to 75 that's better and ty pete to 199 nice one there on the first sapphire auto congrats jeffrey orange cj kafis the 25 for the guardians this one there javish shears and coli on you gotta watch that movie yesterday marvin jones to 175 jay and brice young what is it uh no i've not justin feels 249 no it's a good one jaden reid and kenny macintosh rookies no it's far paton tune silver rookie to at 75 larmy tonsil a chain and demarvion overshown that is zack charbonate at 149 on the uh auto congrats there jeffrey donald and luke musgraff this rpc goes to the sports car jake come on man 230 in the morning to 149 von miller i'll be some slack rpc silver josh palmer nice blue wave puke up to 199 good stuff there jeffrey paybanks and don tavion wicks chad with some uh nc spots thank you buddy silver auto beckham orange justin shorter nice one there treat it taller forest camo jaden reid to 15 that we're on the same page here you rpc zay flowers you appreciate it man it's all jokes oh yeah silver lockdown chase young blue wave jamis the 199 dtr and israel abinaconda you can tell me i suck at singing you know uh redemption is kenry miller rookie uh patch autograph prism silver to 99 congrats on that one the erison cam smith a jalen hurts to at 99 to 275 is uh no 225 colisec here van ness collager cancy and last pot for you jeffrey good luck buddy an orange daniel jones to 249 chase brown and kendre miller that'll do it for your break there buddy thanks again for the sport get i'm gonna ask you my friend ring of fire ring of fire down now i just i put the wrong initial in one of the randoms now you're come on man all right benjamin l have a good one enough we'll go enough perhaps on the junior auto that's nasty that was dope that was nasty that was sweet good to hear good to hear glad you uh got something out yeah that's awesome man good luck going on everyone sam here with late sports car dripping five boxes of 23 leaf art of sport solo edition for benjamin l it's good luck benjamin let's do it buddy turn off with a triple auto early holland kareem benz moholy and alvarez that's insane one of three congrats on that one buddy great start great start pretty gross that's so cool man hard to top that one for sure man that is an ejiro exhibit uh three of five bunch of uh pinstripes nice one there congrats on that it's gotta be yanky yanky ejiro i don't know i don't think you didn't wear 51 with the yanks though they're probably it yeah it has to be though you're right there's no way i can see that alessandro del piro one of five congrats on that one there uh ben some trippin alessandro del piro unless it's like uh japanese sort of yeah it's gotta be yanky jersey but i know for a fact if not we're 51 with the yanks we're like 30 something with the yanks did he i think he did yeah we were like 33 or something maybe 31 yeah something like that uh tyree kill for a 15 on the auto good stuff there uh benjamin i don't think we're allowed yeah not not tonight we're not gonna run the risk not do not tonight we're not gonna run the risk of uh sam being in trouble and you getting in trouble or me getting in trouble mainly sam yeah i don't want you to get in trouble well you'd get more trouble around there because you would be the one letting you do it yeah i got a lot of trouble exactly unfortunately man hey trey young damien lillard dual auto six to seven that's great great five boxes dame time very nice congrats on that buddy i'll do it for your break there my friend thanks again benjamin get him right out to you buddy i'll probably be ripping some tomorrow i would guess you probably uh i'll probably be ripping some tomorrow after brute breaks i would guess probably uh if you're here tomorrow matthew i'll be uh ripping some too no promises but you know how to have a solid man the hauling spends a month that one's nuts dude all right good luck here at brandon one say i'm here with late in sports cards over three boxes for brandon r we got two 20 uh 23 top star wars chrome black and 123 gold standard so good luck buddy is he in there where does he play for i thought he was uh baraco or whatever no i thought he i thought he was uh netherlands because he was from aruba like same thing with bogart well i mean these guys are it's it's wonderful you can play i guess i can be there's literally in the 125 the mandalorian like they go down there and play and 50 is size noodles we got a handmade in agira uh the base auto nice one there uh brandon congrats buddy newt gunray padme amadala and then a gold eath koth 25 of 50 nice one there oh koth padu shared nice one there as well congrats on that brandon that is a chat market and then a 23 gold standard 23 gold standard 2023 gold standard good luck buddy 23 gold standard it is in fact what is it 2023 gold standard car over onto you shan over the 49 sam la porta shan over car see you 75 is uh nick chubb i don't see it dude i don't see it dude unreal tyler algear at 83 out of 299 i'm at forecast and i hear it unreal congrats on that one uh brandon we got a nick chubb gold mine to 299 that is a kenjray miller rookie jersey autograph double that i'll have two uh patch windows for the saints got a jack cambell six of 24 nice one there for the uh lions and then to finish it up it is going to be a dtr doran thompson robinson 99 out of 199 that'll do it for your break there brandon thanks again for the sport buddy get him right out to me okay all right that's going to do it everybody uh here's your link to the break schedule tomorrow there you go um i'm off tomorrow uh you got kyle in the morning kyle and shan with personals in the morning and then um jake and forest starting tomorrow night at 6 p.m so thank you all again do appreciate it i'll see you guys again