Hey guys, it's Nate, AKA the Foot Accountant. Welcome back to the channel. Last week on Monday, we had our favorite Footies SPC, the 85x10 released into FIVI 23, but we were disappointed with the price of the SPC and only being able to do it two times per day. Now, today's a massive day for this one because it is actually expiring today and the question is, is it gonna come back? And if it does, will we be able to do it more times per day or will it be cheaper? We're gonna uncover that, talk about upgrade packs in general and what else to expect with also a leak that has been posted about a Footies player upcoming in FIVI 23 today. So if you're excited for the video, drop a thumbs up on it and of course, subscribe if you are new. Let's go over yesterday's content really quickly because we had a player leak yesterday. We thought that player was gonna be our SPC dropped at Sunday content and instead, it was somebody completely different from what we expected. Ryan Cherokee, five star, five star, he had a Future Stars card earlier on this year, left-footed, nice card. I mean, you like the alternate positions there. He can play a lot of different attacking spots to get into whatever formation you're trying to use. Really great passing stats, really solid dribbling stats. He has the stocky body type, which a lot of people like. It's, if you use Payette earlier on in the year, that's kind of a comparison with the stocky body type. But also if you look at the stats, not that amazing, right? 91 composure, 87 reactions, 90 finishing, 80 strength and aggression. That's a little bit low for this day to the game, but along with that does not come a very high price tag. Only 180,000 coins to get this Cherokee done. It's only two squats. If you run a League One team, this could be a player that you put in there or craft with extra fodder maybe this week. If you want to, I just don't think it's that amazing of an SPC, but it's decent and people really liked his Future Stars earlier on this year. So give it some thought. If it works for you, go ahead and do it. But that one for me is just kind of a mid SPC if we're being completely honest. Now, SPCs that were not mid, that were dropped yesterday are these two right here. Don't sleep on these SPCs guys. The daily bronze and silver upgrade, these SPCs right here can actually get you golds to get into player picks, to get fodder, to basically help you craft all the other SPCs that are out in this game right now, whether it's the upgrade packs, like 85 times 10s, 84 times 30, 90 plus icon player pick, or maybe you're trying to go after Ronaldinho. These two SPCs can help you do that. Yes, you're like, Nate, why would a daily bronze and silver like help me with this? It will, trust me guys. Right now, what you get out of this is 24 bronze players, seven rare, or 24 silver players, seven rare. All you have to turn in are three players, right? You turn in three bronze and you get 24 back. You turn in three silver and you also get 24 back. It's incredible value. You can only do it three times a day, but where it gets good is all those players that you get, you're actually gonna end up putting those into the ultimate bronze and silver upgrade, which the ultimate bronze upgrade gives you more silvers, and the ultimate silver gives you gold commons, and those gold commons, you can then rinse into player picks. Now, player picks are expiring today, the 80 plus and the 81 plus. Hopefully, I mean, it's almost a guarantee, right? We're gonna get some sort of upgrade pack or player pick SPC today as a part of content, and that's where the grind is gonna be really, really good. So if you're like, Nate, I don't have a lot of fodder, I can't craft Ronaldinho, any of these other upgrade packs or player SPCs like Kunde that you may be gonna do right now, get involved with whatever you have in your club, start crafting through these upgrade packs, the daily sprints and silver upgrades. You can do three per day, rinse those into the ultimate and boom, you're at gold cards right there, and then you can go into player picks, get some fodder, and take yourself to whatever SPCs you would like to do. So that's kind of the craft, that's kind of the grind there. I wanted to mention that to you guys because if you're like, Nate, I got nothing, that's a way that you can kind of like resurrect your club in terms of fodder on most of this stage of the game. Big W for EA for releasing that. And of course, it does, of course, satisfy one of the weekly XP, 600 XP, and two more completions on that for getting this week of XP done. Now also, we're talking about today's content already with the upgrade packs and stuff. We're gonna get a trophy Titans Torres today, and that is another SPC we have to do. Basically, today, you'll be able to complete this whole section of XP and probably get up another level with the bonus reward because we should be getting a trophy Titans for a new Torres player SPC today, which would have a loan challenge inside of it, and that is gonna give us some XP to finish off this week. So one other SPC to talk about from yesterday, the 84 times, yeah, it's 30 players in one single upgrade pack. We can do it once and then we have to wait a few more days to get it done again. But guys, we have an 85 times 10, and this one for the price, no, 300,000 coins for 84 times 30 upgrade pack, that's risky. That's really risky for me. I like the 85 10 much better than this one, just because you're turning in 44 players, right? This SPC requires four different squad segments. You're turning in 44 players, four squads, to get 30 back. I don't like that much of an investment to get 30 players back, especially when probably 15 of them are gonna be 84 rated. I know you got a lot of specials in packs. I know you got the footies cards, but that's too big of a gamble for me and too many coins and too much fodder to put aside into that to try to get something good and try to get other upgrades for even your fodder cards, right? Upgrading fodder to get better fodder, right? I like the 85 times 10 much better because it's cheaper and you have an 85 minimum rating instead of an 84. So that one right there, definitely expensive. You can see Footbin has an 8% upvote on that one, which may be a little bit harsh. If you're trying to just pack all the footies cards you can right now, whether it's Neymar, Jesus, Alawaren, yeah, that's maybe a pack that you wanna try, but it definitely is a little bit expensive. Now with the SPCs that we had yesterday, guess what? We have some fodder prices going up. Once again, our daily SPC spike at Content Drop happened again yesterday, but as we head into today on Monday, prices are looking a little bit low again, and I would have to say once again, like we say every single day, I feel like on the videos, guys, make sure you're going out and doing a club stock. If you don't have much in your club, make sure you get some because take a look at Parejo. Yes, they Parejo, 8.4K all the way up to 9.2K. These guys, if we get a good 85 times 10 today, if it refreshes, if we get something else alongside with that today, tomorrow, Wednesday into this week, guys, again, it's that middle tier fodder that could do really, really good if we get really good content, and it's what we're going to need to be completing SPCs. So 83s on up look decent to me.  Still waiting for those to rise a bit. Those are gonna help me out probably with the Ronaldinho SPC as well. But again, watch fodder. Now, one thing we have to talk about with fodder is, we mentioned it yesterday on stream, but if you take a look at the Ronaldinho SPC price, it is up a little bit from where it was, but yesterday with squad battle rewards, the Ronaldinho SPC went from 5.9 mil, squad battle rewards got released, and they went all the way down to five million coins to complete this SPC, because so much tradeable supply for fodder was hitting the market, as there's a lot of objectives right now when people are playing squad battles to get that done, and especially with a lot of players in packs, 150 special cards in packs for best of batch two, a lot of players that you saw dropping the most were 92, 93, 94 rated cards, even something like your 88s dropped down really low. They're like this card or minimum price right now, if you will, 11K for a lot of those 88 rated cards. And if you take a look at Ronaldinho's SPC, the reason that it has gotten so cheap is because these higher rated squads, the 92 rated, these were like 300 plus thousand coins when the SPC was five, six million coins on the weekend, and now they're 285 thousand coins a piece to complete. So if you've thought about doing Ronaldinho, prices are down, right? It's cheaper to buy that higher rated fodder. It's cheaper to buy the middle tier as well. Basically everything from 87 rated to 95 rated is down a little bit from where it was over the weekend. Watch this space, watch these prices throughout the week because more and more people are starting Dinho, I believe, especially if we get a good SPC today for an 85 times 10, that's what a lot of the hype is kind of based around today, is that refreshing. You know, you could see some really big price rises on fodder, I like the middle tier the most though, because again, that's the stuff that people have to buy. A lot of people have the high tier, right? 88, 89s and above because that's all that we're packing day in and day out from player picks and from packs and stuff like that. So I would say maybe hop on the market, do a bit of a club stock. I need to get some 84s and some 83s in my club because that's the part of my club right now that is down bad. I actually do have a couple of player picks which we're gonna talk about in a second, but the big SPC at hand, we've mentioned it a couple times already but that's just because there's so much hype in this game and the menus on this game specifically today are dependent around one SPC and it is this 85 times 10.  Even as we have maybe a preseason promo right before EAFC 24 comes out, this 85 times 10 should be a staple of content and it should be refreshed today, right? I'm saying that with like 90% sureness that I expect this SPC to come back today. I don't exactly know how it will. That's the way the questions come in, right? Will they make it cheaper, right? This last week it was an 84 and an 86 rated squad with a team of the week or a team of the season. So it was a little bit expensive, still doable but a little bit expensive and we could do it two times a day. So the question is, are they gonna keep at the same price and allow us to do it more times in the day? Or they're gonna keep it at two different repeatables per day and make it cheaper, a one squad 85 times 10 if you only have to turn in, even if it's like an 87 or an 88 rated squad, if that is all we have to do, that is a W because anytime you can turn in 11 players in one squad to get 10 back, even if you're turning in an 88 rated squad for an 85 times 10, that's fantastic because that means it's so much easier to grind into craft and that would be like one of the most end game parts of footies if we get a one squad requirement 85 10. So I hope it's a little bit cheaper. I also hope that we can do it a few more times because if we can do it a few more times, I'm talking like maybe five times. I mean, I might be a little bit too early but 10 times a day was something they did last year before making it unlimited repeatable. You know, that's a possibility for today. I don't think unlimited repeatable is a possibility but I think anywhere from two to five to 10 times max per day is what they're maybe gonna allow us to do with five probably being a safer bet unless they just make it cheaper and still allow us to do it two times. So that would be massive but alongside of that, how are we gonna get 85 times 10 done if we don't have any fodder? Well, daily bronze and silver upgrades if you're really down bad but like myself, 80 plus player picks and 81 plus player picks are gonna be the place where we will hopefully get some fodder this week and with the 80 plus is going away and me having some gold in the club, I said, let's send a final few for the video and I really hope they just refreshed this 80, the 80 plus player pick I hope is refreshed but I hope it's refreshed with the requirements of the 80 plus from this last week but it's actually an 81 or an 82 plus because man, remember last week on Monday, we were also so mad because the 81 plus player pick came out and it required an 80 rated squad. That was abysmal and also, you know what? Give me the 81 plus player pick because these player picks are not hitting right now, not a special card and all of these, I did seven player picks and we got nothing. Wow, the luck is not in on these at the moment. Last one, can it save this batch, this set? Wow, that was horrific actually. An 84 rated, three of them for my highest rated, not terrible I guess but I was hoping for a little bit more with all the special cards and packs. I hope we get an 81 or an 82 plus player pick today guys that does not have a rating requirement inside of it. Remember the one they dropped a couple of weeks ago? It was like seven golds and it was an 82 plus player pick. Do that again EA, that would be very, very nice but don't shoot there. Don't shoot there, require an 80 rated squad in any of the player picks that you dropped today. Doing that last week was absolutely abysmal. You better not do it again. All right, we're all trying to craft Ronaldinho this week, let us do it. Let us have the fun with an 85, 10 that is repeatable and also an 81 plus player pick that is cheap. So I mean, if those things come out today on this game that's gonna make the menu grind really, really good and it's gonna give me motivation especially because I have started Ronaldinho guys. We have commenced the grind. We are four squads out of 33. I've done the first three and then I did the first 92 rated squad so we are locked in. We're gonna be crafting Ronaldinho this week. We're gonna be getting arguably the most overpowered and biggest flex card on this game. We're gonna go for it because why not have something to grind for a little bit at the end game. I'm excited to get it done. I'm excited to grind it. It gives me something to shoot for this week and I'm hoping that EA allow us to do that semi well. Also for SBCs, like we mentioned that Fernando Torres is gonna be dropping today as a loan. I would also expect as we normally see that he's gonna be getting a regular version of his icon on the market as well. It should be the 94 version for Torres. I mean, if they released a little bro as the actual SBC I think this game would riot but it's probably gonna be the big bro 94 but that is a part of XP once again. So make sure you get yourself that loan version done. Get yourself XP. So I'm expecting those three SBCs today and 80 plus or 81 plus player pick 85 10 and the trophy Titans SBC other than that. I mean, surprise us that 83 times 100 still looming not in the store as far as I've seen. So maybe I should check that really quick because they did add a store pack yesterday. I don't know if they added any more of them. I didn't see anybody talking about it. So I doubt that they did. I think they added another 500 K pack yesterday once again. Just like sad, honestly, like dude, no this footies premium replay pack which is just best of batch two players. Why would I open a 500,000 coins pack right now that does not include the chance of packing footies cards? No, super ultimate pack is the only pack in the store worth opening unless you're just going to full send it. In my opinion, that pack is 100% worth it if you wanna go in on a store pack there. Now let's talk about market a bit which is like Nate, where is your freaking coins, man? You had like three or four million yesterday and that would be true. I did. And right now what I'm doing is I'm trading a little bit. Yeah, trading in August because last week on Monday, this time early morning, Monday hours were really, really good for the market. And a lot of the footies cards, people woke up on Monday, they got their foot champs rewards and prices on the footies cards, especially the rare ones, the most hyped ones moved. They moved a lot, right? So I picked up a couple of Sanchos at his actual minimum price is 300,000 coins. That scares me a little bit that he has such a high minimum on this Sancho card. But I picked up a couple at 300K, hoping that he could go up a bit. He was down a lot from yesterday. Also picked up a couple of Carva Hall. And I do have a Hezeus as well that I bought a little bit earlier in the day for, you know, I might have paid over, I think I paid 1.13. So he's a pretty rare card. I also packed him yesterday. I was very lucky for my first 85 times 10 to hit Gabriela Hezeus, which was mental in its own right. So I'm going to be trying him out today in the cup. But I also bought one of him to try to trade and to make a quick flip out of it because that is the fluctuation that we saw last week. We also saw in week one of footies with those cards is they were very low Sunday night into Monday and they ended up rising a bit into the middle to latter part of the week, as it was just kind of like upgrade pack content on Monday and a little bit slower. Now speaking of the cup, I got to grind the cup this week because it is so worth it to try to go after those 15 wins to get all the packs, to get the players. And I think this is the team that we're going to do it with trying out Parasich. I've got my footies players in there. I'm basically just using my main team in the cup. I used that team in Weekend League with a tall at right back instead of Parasich. Kind of choked it, got 10 wins, but we were in a hurry, just getting the games on as fast as possible. A little bit of a speed run, if you will. And that's why I think that kind of ended up there. Oh, also have to end the video with a little bit of conversation about this leak right here. I don't know if we're going to see this player in the ultimate team anytime super soon. This to me, guys, feels like a player that's going to be in team four. It's almost, I almost said three, but team four of footies. This feels like an impacts card to me, right? We haven't had an Ansu Fati in a while. And the Ansu Fati that we had earlier this year was actually an SBC. I don't know if you guys remember this out of positions Fati card. It was like very 50-50, right? A lot of people loved it. It was a great card, very overpowered. He was kind of released during the lengthy meta and he was explosive, so it was the opposite of that. And some people liked that card earlier on in the year, but he was also pretty expensive for a early November SBC. So he is leaked to get a footies card. This could be an SBC, guys, it could be. But the fact that Sheriff leaked it as non-SBC, he didn't say that or objective. He just said Ansu Fati is coming as a footies soon. This feels to me like it could be a card that is in packs. 96 rated is just a prediction. It's not a guarantee for the rating. But that just seems like maybe the second or third tier card to be in packs, in my opinion. They can make him a 97 and kind of make him like Jesus. Kind of like one of the top three players that would be in packs this Friday, probably alongside like a 99 in Bapay or Erling Holland. You could, I would very easily see a 99 rated Holland or a Bapay or something 99 rated this Friday in packs with a footies team four, which we are expecting because team three is going away. So of course I'm assuming this, this footies promo is not ending, right? Cause the batch two is still in packs for the week. So we're expecting more cards in packs on Friday there. So that's kind of a rundown of what's going on in this game right now. I mean, other thing to look out for this week would be guys, the beta. I mean, we talked about it a little bit, but that's just kind of like some EAFC 24 news. You may want to keep an IL for it and you may want to just be ready to check your email for it. Make sure once again, you've got all your email notification stuff and things turned on in your settings. I think it's actually like account marketing settings or something like that because I think it might be here pretty soon where EA starts to dish out some of those codes. And we start to hear people talking about the EAFC 24 closed beta, which is invite only. So we've made a couple of clips about that in the clips channel. Make sure you check those out. And yeah, guys, it's almost time, right? I mean, we're getting into the middle part of August. We're probably going to have some more news on if I could actually pull this up with EAFC direct. We're going to have some news on deep dives coming pretty soon as well. We just had the matchday experience. Ultimate team, maybe this week, guys, maybe this week. I don't know if they'll like push that back into next week or something along those lines, but we've got three reveals coming in August. We just had the matchday experience last week. So maybe this week for Ultimate team and clubs coming soon as well. So be on the lookout for some of that, of course, with all the news when it comes out. We'll be covering it. We'll be talking about it and going over it here. But the most important thing is today, EA sports. Drop that 85 times 10, repeatable. Either make it cheaper or let us do it more times per day. We need to grind the menus.  So if you enjoyed the video today, guys, drop a thumbs up on a comment down below. If you have any questions, of course, subscribe. If you are new, I'll see you guys in the stream today. Link down in the description if you want to check that out. It's been Nate from Accountants. See you guys there. Peace out.


So we're in the end of the home stretch How do I manage the side effects of the treatments that I am taking? Many of you in the audience know Nancy Moldauer who's the nursing director of the kidney cancer program and has been such at UCLA City of Hope and here at Cedar Sinai Nancy Thank You Dr. Ficklin for it was Dr. Ficklin mentioned earlier today Today's program was a series of questions that we feel we wanted our patients to have answers to But the number one question that I'm always asked is how long have I been working with Dr. Ficklin? So just to set everybody straight. It will be 29 years in March Who's counting? So I know you know all the names of these drugs we they were talked about at several time points today and As I know many of you are receiving these medications But what I really wanted to focus on was how we can best prepare you before you start embarking on the treatment So I have about 15 questions. It's gonna go fast and I wanted to throw them out there And as you always do, please let me know what questions I have forgotten that are important to you So I'll start with why is this drug being recommended for me? I think it's important that you know that and that's the number one question As to why your physician is recommending a particular drug and again I think what you've heard today so much evidence as to why one drug over the other what's first line what's second line Which leads us to the second bullet point. What evidence supports the use of this drug? Why am I be why is this drug being recommended for the first time that I'm receiving a targeted therapy? And then of course should I be considered for a clinical trial if yet if yes Which one would you recommend and if not please tell me the reasons why are there any treatment guidelines? Associated with the medication you really need to know what medications you can take with the targeted therapy Which ones are contra indicated? How do these medications work is this chemotherapy? Everyone in the audience today I know knows that this is not chemotherapy, but I can't say that it's true for the rest of the patients that I take care of This is not chemotherapy. It's very different and the mechanism of action is very different Is there a role for combined for combining treatments? We don't get asked that all that often But in the past we used to because in the past we were combining a lot of these agents together But what we found is that there's they're much more toxic when we put Two targeted therapies together and what are the pros and cons of an oral drug versus a drug that's given intravenously? What are the side effects? What can I do to improve them? How long will I be taking this medication? How will I know if it's been successful? Will I be able to travel should I continue working? How will this affect the quality of my life? What financial resources are available to me? Is there any special diet? I should be on can I continue to exercise? How often will I need to see my doctor? When and who do I call if I have a problem? So one of the key items to discuss and I think it's important that you understand what angiogenesis is because it will help You understand the mechanism behind the treatment that you're getting You need to discuss with your health care team a follow-up schedule Just because we give a prescription and we expect everything, you know to like it within a day or two You're going to get your prescription. It doesn't happen that way in our practice We put patients on a very rigid schedule for the first month of treatment and we follow them very closely with monthly treatments monthly follow-up visits You need to share with your physician the past medical history What current medications you're taking and if you're going to receive any elective procedures? One of the side effects with these agents is that they can cause some problems with bleeding So you want to make sure that you stop your medications if you're going to have an elective surgery But not only are the bleeding problems a concern, but we have to be worried about wound healing So sometimes you have to wait up to 28 days even after surgical procedure before you would restart And who do you again? Who do you call for the side effects and how are they going to be managed? What time do I take this medication again? What foods can I should I avoid and? Keep a medication and a blood pressure diary it really helps when you come to have when you see your physician and you can show them either The blood pressures from the previous week the previous month so they can look at the records and they can actually actually see the numbers So for some people and like myself, you know a picture is very helpful in terms of understanding the mechanism of action and then this simplified slide What I just wanted to show you? There's the tumor cell in the center and we know that tumors can Secret factors that actually promote the growth of blood vessels and you can see the the blood vessels kind of opening up towards the tumor and That's exactly what we tried to prevent by giving you these medications that block the growth of blood vessels to the tumor and In the second picture You can see in the red Boxes Here's temporary limus everlimus by the CIVAMED synitinib seraphinib exitinib and fizzopenib and This is a blood vessel This is a tumor cell and you can see where these medications They block all these internal Pathways that lead to cell growth and also the formation of new blood vessels So this is what these drugs do they actually you know They're putting the brakes and as Dr. Figlin often often says it's like putting a block on the dam So that all these internal Growth pathways that the cell knows what to do doesn't get get the signal so the tumor doesn't get the nutrients and doesn't grow it's a bit Challenging and at the same time frustrating in terms of managing the side effects associated with these medications we've been prescribing them for a decade now and I can't say that we better understand the mechanism of action of why You get these particular side effects We have some idea, but it's not a very good explanation as to why they occur So I can lump in the in this column the VEGF Medications that will cause a certain Collection of side effects we talked about the skin changes and well I'll go into that in greater depth increases in blood pressure Fatigue Stornness of the mouth change in bowel habits some laboratory and urine changes loss of hair color Definitely change in appetite and taste and some bleeding and it doesn't necessarily matter if you're on suit tent or Votrient in terms of developing hand foot the way in which we treat it is the same But if you're receiving an mTOR inhibitor on this side Frequently when patients go from The VEGF class to an mTOR It's a much easier transition in terms of the side effects, but I wanted to point out two side effects that The pneumonitis and although rare is something that you need to know about if you're on an mTOR inhibitor and Simply I can describe it as inflammation of the lung tissue and Although rare when it occurs it needs to be promptly recognized and treated and if you develop a cough a fever Some shortness of breath you need to bring this to the attention of your physician right away and The other unique side effect associated with the mTOR inhibitors is that you're going to see some changes in your blood Chemistries elevated glucose lipids and triglycerides again The this class of medication tends to be a little bit better tolerated than the VEGF inhibitors But I just wanted again to point out these two a little bit different class side effects that You do need to know about so we can talk about hypertension and it pretty much is anticipated with all of the TKI's Taking a baseline blood pressure is very important Frequently we initiate or adjust antihypertensive medication We can we would try to monitor blood pressure not always needing to interrupt the dosing of the TKI and if you Bring these if you have a good working relationship with your physician and your team who's taking care of you You don't necessarily have to interrupt the medications because you're prepared to do some dose adjustments of your Routine antihypertensive medications This rarely occurs with the mTOR inhibitors and although we usually see it within the first four weeks of therapy It definitely can happen sooner Which is why we start the medication the blood pressure diaries on the first day of treatment And also as mentioned earlier that hypertension is a biomarker of efficacy in kidney cancer So if your blood pressure increases it may mean that it's working We like to maintain the blood pressure less than 140 over 90 and Again, as I mentioned you you're going to monitor very closely during the initial weeks of therapy There's no specific recommendations as to what antihypertensive to use and also to anticipate blood pressure changes if your dose of the medication is modified or if there's an interruption in in your treatment and there's some Really easy blood pressure of cuffs on the market today This is one that you can wear around your wrist and it does do a very accurate of blood pressure measurement and Perhaps one of the mechanisms that we know about why these medications cause hypertension And that would be the effect actually on the arterial walls And it doesn't allow them to dilate as well when you're taking the TKI and the blood pressures What we're measuring is just the force applied to these vessels at every time the heart contracts So we know a little bit about why this occurs But more importantly, it's the management of it that is number one so fatigue is a universal symptom with these targeted therapies and And we have treated so many patients through the years and Have tried to guide patients as they go through this is that the first couple months or the first couple cycles of this medication will probably be the most intense and Although it's very difficult to kind of accept that when you're starting these medications they actually it actually does get better over time and We have patients now who? Beyond years taking these but generally after the fourth and fifth cycle They're beginning to feel that the side effects have subsided They're getting back to their baseline and they're kind of you know feeling better And their bodies appear to be adjusted to the side effect. So the fatigue indeed will improve The way in which we manage it well, we'd like to screen for other causes if it doesn't go away We don't want people to kind of just lie around all day Develop some type of walking in the morning walking in the afternoon If if a hike or a long walk for 45 minutes tires you out then take a 10 15 minute walk twice a day So you can kind of conserve your energy if you're not sleeping at night. Let your health team know When fatigue Is just so overwhelming we will interrupt the dose and make a dose Modification because our goal is to keep you on this medication and we also want to keep you You know have a good quality of life The next area of side effects are the skin toxicities and these can these are really They range from just a dry itchy skin where there may or may not be a rash to a full-blown rash on the skin Handfoot syndrome hair thinning Generally speaking you will not lose your complete set of hair when you're on these medications But thinning can definitely occur. We see changes in the colors where the because you're going to lose your pigmentation Skelp itching and burning that tends to occur kind of in the beginning of the treatment Inflammation of nail beds and a small incidence of some skin cancers have been noted on patients who have been on the TKIs Here's some pictures obviously Handfoot syndrome and what we notice very frequently is that they seem to appear in the creases of The toes and I'll show you the hands on the next slide and these are incredibly painful They seem to occur in the pressure areas like these could be areas of tight-fitting shoes But also you have to be aware that you know it can occur in areas that you may not expect it So it's very important to carefully examine one's feet and Here's pictures of some hands that had developed some hand foot again in the creases very painful and here's a large area of Calcification well it looks like if the skin becomes very Hard and looks like a blister, but there's actually no fluid underneath the skin What's important is to recognize the early signs of a hand foot syndrome. It can be redness pain tingling and It typically can occur as soon as two weeks into the treatment Up to maybe six weeks or into the maybe the you know sometimes a third cycle. I Think we're doing a much better job at managing the side effects only because we are much more proactive and working with our our patients in terms of starting the use of Moisturizers early on and the thicker the moisturizer the better Informing you to avoid streams of temperature pressure friction to the hands and feet and whenever possible use we're really good shoes and The insoles or gel inserts do help with the hand foot other like common sense things if you if you develop Hand foot on your hands avoid wearing rings. We don't want the rings to get caught Avoid wearing tight fitting shoes use gloves if you're going to do housework gardening work You know, it's difficult to limit the amount of exercise that you like to do and the amount of walking But if your feet are beginning to get painful and if you continue to kind of pound the cement or the surface You're going to have an intensification of the hand foot pay attention to signs of infection and always use some block and avoid direct sun exposure and If all these preventative measures that we talked about are not successful then we do have to have a treatment Interruption and sometimes modify the dose I'm happy to provide this as a handout to you. These are all Different type of products that we use to treat this Recently I have we've been using some prescription Ointments that one is called urea cream the other is cobetasol and they seem to have some a little bit more effectiveness in treating some of the very tough Calisteria's on the hands and feet but again a lot of this is our experience and it's anecdotal We don't have any very good research studies to tell you What? Moisturizer is the best so it's a lot of trial and error and here these are all the products that they're over the counter They're not expensive and very helpful in treating this side effect so moving on Lot of patients will complain of or develop some GI side effects associated with these medications the mouth sores Kind of a burning sensation in the mouth heartburn Taste changes decrease in appetite does the vomiting actually minimal It's rare that we ever have to actively treat nausea and vomiting with any type of prescription medications But there's diarrhea constipation although rare can occur and Then some bleeding from the ball again rare. So if you just think of your entire GI tract being Effective by the TKI's You can see how these side effects kind of set in We make recommendations for how to modify your diet I think you're going to be the best person as to know what foods work and what foods will not We recommend always before starting these medications to having over-the-counter Amodium at the house and we give very specific instructions as to how to use it and Also the use of an antacid because there is some heartburn associated with these medications and if we can you can take some over-the-counter And acid that definitely does help and to alleviate that while you're on the treatment and here's just some of the over-the-counter medications that you can you should have at home and In terms of the diarrhea we talked about the Amodium which is easy for you to obtain, but if that is not effective Then we can prescribe some prescription medicine, but the most important thing is that you need to Contact your health care team when these symptoms occur We don't like to hear that these symptoms have been occurring and we don't know about it It's very easy to become dehydrated and It's easy to do this when you're having you know eight to ten episodes of watery diarrhea a day The other area that's very important also related to the GI tract is really the condition of of your mouth and It's becoming more and more frequent that before you actually start these medications that you visit your dentist and and have a Dental hygienist cleaning of your teeth because again We don't like to have to find things out once you're on these medications that you need to have a tooth extracted or you have a gum infection Simple things like avoiding alcohol mouthwash. We can prescribe some Mouthwashers have a little bit of anesthetics to it probably the best Measure is just warm water rinses up to six to eight times a day if you're able to do that Sometimes we have to change to a children's toothpaste that is not as minty or as spicy And there are some prescription things that we can also recommend when the stomatitis just gets so intense that you can't You know, it really affects your eating again. Here's some again over-the-counter easy interventions that you should have at your disposal while you're on these medications so that you can be very proactive in preventing them and Again, this is one side effect that over time will definitely improve the major medicine the major food that should be avoided on most of these medications is grapefruit and The reason is that it can actually affect the the level of the tki Making it a little bit the level a little bit higher and the incidence of side effects greater and Looking at the top section the snitinib everlimus exitinib those could be taken with or without food. It doesn't matter Snitinib generally is taken four weeks on followed by two weeks of rest Everlimus is daily dosing and exitinib is a medication that's actually taken twice a day or every 12 hours When you're dosing with seraphimib or pizopinib, it's a little bit trickier It should be taken one hour before or two hours after a meal. So if you're on other medications You have to kind of fit in when you're going to take this medication in relationship to when your meal is going to be Seraphimib is given taken twice a day and pizopinib once daily Tems serolimus is given as an IV infusion every week and the combination of bevacivin that it interferon The bevacivin is given IV every two weeks. Where's the interferon as a subq injection? some specific side effects associated with the mTOR inhibitors and And the first one really deals with tems serolimus and that's the medication that's given intravenously and the thing that you Would want to know about and and the nurses who would be administering this medication to you would be the possibility of allergic Reaction during its infusion and that could be manifested by feeling short of breath having some back pain and these are things that a Nurse would be watching you very carefully and observing you during your first infusion with this medicine Also lab abnormalities. I mentioned the increased blood sugar cholesterol and entry increase in triglycerides These are blood tests that should be monitored about once a month And if you can do it at fasting that that's even better And also as I mentioned to always report the nuance of a cough shortness of breath or a fever because we would want to rule out any type of inflammation To the lung so as always We're trying to improve upon the medications that we have to treat kidney cancer and with that always looking at medications that might have a Side-effect profile that's a little bit better tolerated and at the same time having greater tumor control We're looking for a prolonged progression for your survival for those patients who are on these medications with metastatic disease Continuing to have tailored treatment options for our patients and as you heard earlier today the newer treatments being studied the checkpoint inhibitors or the PD-1 and the vaccines and Maybe in the next year or the year after when these newer medications are approved I'll be able to have some intervention some nursing interventions for how to take care of The side effects associated with these medications as well Any questions time for a few questions by for Nancy You can see that her experience is extraordinary


Hey everybody, this is Derek Christian with Cleaning Business Today and like most you also know a cleaning business owner and it has been a while since we've done a lot of product reviews and we decided we were going to do one on a product we use in a lot of our cleaning services which is the Protein Backpack. Now they've got a new vacuum out that we tried out which was the ProVac FS6. I'm going to throw some literature up so you can kind of see it here in a minute in one of the cups so you can have a little more detail on it. And while it looks a lot like the other vacuums they've had out for a couple of years, we got some really good feedback from our cleaners and there were several things that they liked about it. First of all they all commented how late it was. The vacuum itself is under 12 pounds in weight and one of our cleaners felt like she could do jumping jacks with it on which we thought was a pretty good statement. In addition the new harness seems to pull off an interesting trick where it has an air gap between the body and the vacuum which makes it so it doesn't get as hot and you don't feel the vibrations yet at the same time the cleaners all gave us feedback that it felt like a tighter fit it was more maneuverable and that it has smaller profile on their back and they didn't feel like they'd potentially hit things with the vacuum.  And we've got some comments here from one of the cleaners that we're dropping in. Okay so what about the cushion in the back? I don't feel the motor as much back here. Mm-hmm. Here. No. Okay. So that sits better and there's no more cushion. I don't feel the heat or maybe the vibrations as much on the motor. Straps are comfortable. They look more padded. They do feel like they are padded properly. Up here it doesn't sit on my back. It's sitting on my waist. So that's helpful. Okay. Mm-hmm. Okay. I see. All right. Good. Yeah. As long as you're strapping properly it's comfortable. You might be jumping down. Where did you turn on the power head? Power head turns on here. Okay. On the handle you have to turn on the power first and the cord has to be loaded. Okay. We also got a lot of feedback about how much quieter the vacuum is. And in our video the vacuum is pretty loud because when you record it's always loud but we were testing this at a senior living facility that we cleaned. And we were getting feedback from the residents who lived there that the vacuums were noticeably quieter than the vacuums that we'd been using previously. Which was not something that we expected. No one ever says a vacuum is quiet. So that was also really good feedback to get. We also got good feedback on there's a new power switch and way that the power head connects to the power switch. And we were told that it was easier to activate more logically located and that the prongs weren't as prone to break or hard to connect as it was in the last one. And really interestingly the cleaners who were using this were smaller. One of the cleaners was only five foot one and all of the cleaners who used it said they felt like it was better designed for smaller bodies and for female bodies and like somebody actually designed a harness that was comfortable for women and had women in mind. So that was also really interesting feedback that we got from the cleaners. So overall we were very happy. All protein backpacks have great suction. Have great filtration just like we always expect. They were very quick and easy to maneuver just like we always expect with protein backpacks. But we got feedback that they were lighter, easier to maneuver, more logically located, more comfortable. And like I said, you could even do jumping jacks with them. So if you're in the market for a backpack vacuum, we'd highly recommend you check out the new ProVac FS6. We were pretty impressed with all of those features and we think you will be as well. And as always, follow us at Cleaning Business Today including our YouTube channel. Thank you.


Wel, dyna'r toffi TV, yr ystafell yn 11 ysgol, West Ham United vs Everton 5'30, Saturday night at the London Stadium. I'n gael straight into it. In Gold, Job and Pickford, England's number one. A dde, he's been good, he was good against Chelsea, he'd had a rocky game against Newcastle United but he has come back stronger for Chelsea and obviously played a couple of games for England. He's our number one, there's no-one really to challenge him so that's an easy decision. Right back, Seamus Cullman, again he's another one, Seamus has really picked up. In the last few weeks his form has got better and better. Obviously missed out on the trip to Newcastle which we lost, but a captain d'Island the other day so he's in. At right back, left back, Leucadine, I thought he was going to miss this game but Marco Silva in his press conference saying that Leucadine is training and is in contention for the weekend so if he's fit, he plays for me, he's been fantastic all season and therefore he plays for me. Gold scorer for England, Michael Keane, he's been in much better form this season than last season resulting in him getting called back up for England playing both of England's games this week. Alongside him, Kate Zuma, obviously Gary Mina played well against Chelsea when Zuma couldn't play and we thought we were going to see Mina now till the end of the season trying to stake his claim and long be old he goes away with Columbia and gets injured. Marco Silva has said it's not good for Everton and it's not good for the player. He didn't rule him out for the rest of the season when he was asked that question because Eddon said no, no, but you get the feeling it's probably going to be three to four weeks at least that means it'll be out for so Zuma will come back into the side there. Into midfield, I've gone with Ghana who has been excellent I would say certainly in the last three or four games. Alongside him, Andre Gomez and Guilfee Sigarton ahead of them. Guilfee's scoring in his last game, of course, against Chelsea. He's been in fine form this season, 12 Premier League goals. Off the left-hand side, Bernard has been, again, another one who's improved and I think he will benefit really more than anybody else I would say or maybe with Gomez in having a pre-season. Should Andre Gomez stay, of course, but I think we'll see more from Bernard next season but he's been in excellent form of late as well. On the left, Richard Charleston on the right played both games for Brazil last week on the right-hand side following on for his performances for Everton on the right-hand side and through the middle, Dominic Calvert-Lewin. Dominic has really grasped the opportunity to lead the line for Everton over the last few weeks and insists against Chelsea. It was his header that kept us safe before Richard Charleston scored. I think he's done really well, he's improved so much over the last six months and he deserves to be leading the line. Obviously, Jeng Tolson scored a couple for Turkey in midweek and Marco Silva said that was excellent news for him and for us, of course, as a club but Dominic Calvert-Lewin played well against Chelsea last time so I want to see him really making a nuisance of himself this weekend, running channels, getting in West Ham defenders' faces, putting himself about and if he does that then he'll leave from the front and it'll help Everton achieve a result. That is the team I've gone for. Let me know if you think any differently in the comments below. If you haven't subscribed, please do so. It only takes a second and if you want more videos, get over and join the community over there. Thanks for watching. See you later.


US Air Force Airmen, assigned to Alaska Air National Guards Arctic Guardians from 176th Wing. To conduct the, air drop of a multi-purpose wheeled vehicle, from a Boeing C-17 Globemaster 3 takeoff. During the Joint Pacific Multinational Readiness Center, Atowahu, Hawaii, November 4, 2023. Joint Pacific Multinational Readiness Center, is the Army's newest combat training center and generates readiness, in the environments and conditions, where our forces are most likely to operate in. Joint Pacific Multinational Readiness Center, includes over 5,300 training participants from across the US Joint Force, New Zealand, the United Kingdom, Indonesia, and Thailand.


I appreciate you and now let's go a little Q&A. Nice, Tisha Rao, is that a true classic? It is a true classic, T, thank you. It is, and my back's feeling really good. Shout out to Lenny for guiding me to an acupuncturist here in Puerto Rico. Man, I feel pretty good today. And I just had an MRI, if you don't know, I've got a herniated disc that's killing me, but they feel pretty good. I'm actually able to stand up. I mean, for a long, like over 30 minutes and not thinking about passing out, it's pretty good. Ah, hey, Rob, can you put me somewhere where I can throw against the quiche? I want to take it off the exchange. Here's an option. Well, first of all, you can stake it if you really want to, but what I have it on right now, not the best option, but it's a better than a crappy centralized exchange, which they'll go down and who knows if they rug your, who knows if they take your money like FTX or something like that. You can put it on MetaMask. Now, there's different ways to do it because with MetaMask, you have the Ethereum chain, you have the BNB chain, you have the polygon chain, you have all these different chains that you have to use. So it's a little bit difficult. What I need to do is make a video on how to open up all those different chains and then you can bridge them through without getting scammed out. So that's where I have most of them right now on a hot wallet. Not the best option, cold storage wallet's the best, but that's just honestly what I'm doing. James, James is the chartist, check his predictions where I was the realist. Yeah, I mean, look, everybody's got their idea of where things are going. I don't know where things are going. And I love all those graphs and the TA people. It's very fun. It's very fun to watch. But at the end of the day, you just got to take a look at and go, if they're wrong, what am I missing out on? And if they're right, is this the time to actually go all in? And do I want to put everything that I have into a chartologist? Some people are really good at it, I miss not. That's why I dollar cost average. That's it, Rob money. Yeah, and I will, this probably won't be a very popular opinion, but there's this website. And people who have been on my channel for a long time know what I say. There's this website. It's called Dan Teaches Crypto and it's 100% free and I don't even spam you. I just tell you when I upload some videos that are in the members area. But there's this post that I did on September 23rd, 2020. And I talk about before you make your crypto millions and I read it again and it is the same advice I'd give today. And what this, if you don't know, like I retired all the way back in like 2015, six, I don't know, the years kind of rolled together. And when you have a lot of a good amount of money where you don't have to go to work, you don't have to trade your time for work, it's great at first. And then the thing becomes this, what do I do now?   So I know some people will say, Rob, I know what I'm gonna do.  I live in Puerto Rico.  So read that blog post and hopefully it'll kind of put you in the right direction before you make it all and lose it all. Just like the NFL players, right? Those young kids that come in, you know what NFL stands for? Not for long, because it's a statistic that most of those guys lose anyhow. CASPA, yeah, CASPA much while. CASPA will probably be a top 10 crypto at some point. And yeah, it looks good. I haven't done a deep dive into it. I am so deep into other different ones. But yeah, see CASPA and CASPA, who knows if it is or not? I'm just guessing like everybody else. Good strategy. No, Ben's chair is here. I sell using volatility on the caters and loaded timeframe so far, so good. It's a good one to do. Some people will like to use just few ingredient index. Works out pretty well for them. I mean, it works out great for buying. The selling parts, Ben actually did a video on this. It was pretty interesting about how when you hit extreme greed, I think it was, he was talking about Ethereum or Bitcoin.  So, you know, you could, I think the example was you could have sold it like 250 or 300 or when I hit over $1,200 because it was all extreme greed all the way up. So it's one of those things really, I don't know. Hey, Biggie, it's been some time, man. Always good to see people come back. And remember, everybody, once this hits, once these indicators hit, I tell you when I sell and you know I'm leaving this channel. So I'm not not leaving for good, but the channel will, I'll probably play some, a couple of videos on loop, which will be like this video where I talk about don't make these mistakes. Second loop would be when I sold 80% of my crypto and I won't come back until the bear market.  I don't wanna deal with that.  But once that happens, I'm just gonna step away for a while and maybe hopefully people will be like, hey, that guy Rob sold, maybe I should think about doing that before I ride all the way up and all the way down. I'll be back at some point, but I'm not sticking around for the craziness. Zap says, I'll make some music videos. See, if it gives you purpose, that's all it is. Improve yourself and those around you. DR says, Rob would really like your penny. Do you think USDT is now safe enough to go into when it's time for the next bear market? I always get these things confused. Are we talking about Tether or is this, I'll just get this one. Because on different exchanges, yeah, it's Tether. Okay, so I'm gonna make sure. On different exchanges, it's different. So USDT, I will tell you one thing. I have thought for the longest time since 2019 that there was something wrong with Tether, that there was some issue going on. And of course, they were in the BDI, the British Virgin Islands and they had these audits and it was kind of sketchy and didn't really know what was going on. However, if you look at the timeline, how long have they been around? How many things have collapsed that you know of? Well, I know of four different exchanges that have collapsed. I also know of many a project that either rug pulled or just totally screwed everybody over or just collapsed themselves. Yet, Tether is still around. So while I say that Tether is like the greatest thing to put into everything, no. It's the same thing with cold storage wallets. You know, I have three cold storage wallets. I have a ledger, I have an ellipal and I have a tandem.  So I split it all up. The same thing would be for your stables. I would say that if you want to put things in stables, maybe do USDT, maybe do USDC, then also Tron's stable coin. Hey, well, that is Tether because it's Tether on the Tron rails. But yeah, that's what I would do. Can you get a Benjamin Barrett indicator for alls? Hey, we're doing the NFA live show tomorrow. It should be a good one. It's on Guy's channel. Great questions. We already got them. It's got a fair amount of say. There's a good one about the greater fool theory. I really want to dig into that. That nail. Dan, I have sold my crypto at 25K. Should I buy now? Cause it's going up or should I wait until it goes down to 15K and you're not giving me a financial advice? If it was me, you know what I would do? I would probably dollar cost average because it's like, there's two schools of thinking. And a lot of people say, no, no, no, you gotta lump sum cause lump sum is, it gives you outsized returns. You got to do it now. The thing is with that is when you put it all in, let's say we do get some blacks one event. Who knows? Maybe World War III breaks out. Maybe, I don't know. There's a double spend that happens with Bitcoin. I know these things sound a little bit far fetched, but you never know. Do we ever think that FTX was gonna go down?  Well, then it did. You think Mike Novogratz, when he was getting that sweet tattoo on his shoulder was like, you know what, maybe this thing will collapse. Nobody was thinking that. So for me, what I would do, I sold my crypto at 25K. I would just say, well, you know, I think I'd probably want a dollar cost average because guess what? Just like yesterday is gonna be dips and it's not gonna be dips. Maybe you could do this. Maybe I would think about doing this instead of dollar cost averaging every single day. Maybe do what's called value cost averaging. Ever heard of that? That's where you'd say, let's say you got, I don't know, 10,000 bucks. And he said, okay, on the first of the month I'm putting 2500 bucks in on these crypto or this one crypto. Then two weeks later, 2500 bucks. And then two weeks later, 200 bucks. And that's value cost averaging instead of dollar cost averaging which is like every single day until infinity. So one of those would work for you. I don't know which one, because that's what I would do. I'd probably value cost average at this point. Well, thank you. I didn't know I had it in me. I've been married for like 20 plus years. All right. Selling most of my alts, holding my Bitcoin. Yeah. And remember, that's usually how it goes, right? So we get Bitcoin. Everything starts with Bitcoin. And again, if you watch that video, which again, links in the description, looks like this. Why when I'm selling ever selling my crypto? Which gets a lot of views. But this one, don't make these crypto mistakes has like 25% of the views that this video has. I don't understand why. Probably cause people don't care about the mistakes. But it's not how much you make it's how much you keep. So, you know, for this one, and I talk about this, everything starts, it flows into Bitcoin. Take a look at these PyCycle Top, these MBRVZ scores, these Pell multiples, and start to realize that things are gonna flow into alts. When they flow into alts, then we take a look at these different indicators, and we can see when we sell those. And you're not gonna nail it. If you get within 60% of the top, consider yourself lucky in this move from there. So that's what I would do. That's me though. Hello. You can turn off live chat comment while continuing to post a video. Yeah, I could. But then I'm gonna get a bunch of questions and like this, then I wanna do that. I just wanna have people just, here's the information and you do what you want with it. Because then people are gonna ask me like, hey, Rob, there's this sweet, you know, new crypto out. Maybe I could, I can just ignore those questions. Rob, do I need to say Rob before I sell my questions or is that a million questions? There's a lot of questions. I'm feeling pretty good. Like if this, usually like on this point around 36 minutes is when my back starts to give out. And I have to stop, but still doing it. I feel great today. Ah, the road to recovery. Which leads me, remember this, a healthy person has a thousand wishes and a sick person only has one. And just remember that if you have your health, you pretty much have everything. Because when you don't, it makes things exponentially more difficult. So be thankful. What's your favorite cold storage advice wallet? It's a tangent by far. As a matter of fact, I just got the new ones here, which is pretty cool because now you can have a seed phrase that you can write down a mnemonic phrase or you can just have it plastered into the card itself. I just like having in the card itself. And if you are trying to figure out what a tangent, the tangent card wallet, Jesus, so it looks like this. That's it. And then I just put that, I mean, if I wanted to carry it around, just goes in my phone. So like, I think this is gonna onboard a heck of a lot more people for cold storage devices because if your significant other parents, grandparents, if they know how to use a debit card and maybe have an app on their phone, they can use a tangent with ledger, a little bit more difficult and that's it. And then of course the other people, like Michael Saylor says, the banks will custody their crypto. And I'm just, I'm not gonna debate them on that one because there's the way things should be and the way things that are gonna be. And the way things should be is everybody should cold storage their crypto because I don't wanna give it to a bank and let them a fraction of reserve lend all my different crypto and make Bitcoin paper out of it or whatever they wanna do, just like they do with my money. I wanna have that in storage. That's the way it should be. How it's gonna be is that the majority of people coming in will tell them all these lessons, will tell them about Mt. Gox, will tell them about Celsius, will tell them about Voyager, will tell them about FTX and BlockFi and everything else. They'll be like, well, that was a year ago. There's no way that could happen again. Here you go, bank. And of course you get Bitcoin and crypto at the price you deserve. You also can only learn from pain and that's really what it's gonna come down to. So long answer for me just to say I like the engine. Oh, John Louise. Hey Rob, Commerce Bank needed two years to obtain their license for crypto deposits. Do you have any info about other banks in the same process? No, but I remember covering a story about NIDIG and they were working with the medium to larger, actually mostly the small to medium sized banks to give them or to get them licenses so they could actually custody crypto. And I said, this is a great move for banks because they need the revenue to come in in this way because they are losing the brick and mortar stores. I didn't really hear too much about it. That of course is in the United States which we got our guy Gary on the job and he's doing a great job protecting you from nothing. So it just takes a little bit more time. All right, that's good. I guess guys short YouTube hysterical the crypto prone his wife. Oh, I did, I missed that one. I'll ask him about it tomorrow. Now here's a good question. Rob, have you tried Heineken Silver, Greenlight Bureau, City Still Holder, have faith in V-Chain? I do have V-Chain somewhere. And on Sundays when I talk about the different things that I'm dollar cost averaging, it's like 10 different cryptos, maybe 12, I forget but that's just the ones I'm actively dollar cost averaging.  Avalanche, I bought Solongo and just didn't really sell as much as I was supposed to and a host of other things. V-Chain and EOS and God knows what else I have in there. So I still have faith in V-Chain. I think it's a decent project.  It is like, oh, numbers go up and that's it. So that's what I'm out of here. Oof, Nas, who is a new moderator? Congratulations, Nas. I'm still feeling crushed. My wife disappearing and leaving, learning of her affair. I thought she was from my purse and would have children found together. Well, thank God you didn't.  So be thankful because when you find the right one you want to deal with that nonsense. Yeah, mind us too. Ben's chair. You should know, Ben. What time is NFA? I have to make sure Ben gets his scat. For it's 9 a.m. Eastern time and 6 a.m. Pacific and 10 a.m. AST, Atlantic Center time here in Puerto Rico. Bobby, you don't need a hardware wallet. Yeah. Agree to disagree. He was taking cold showers. Yeah. Yeah. I mean, it worked out, I guess. Don't sell your alts. Yeah, don't sell your alts. Not yet. Remember though, wouldn't hurt to take some profits. I'm not talking like 50% but just remember to take profit so you remember what it feels like to sell something. And also that helps a lot. It greases the wheels and kind of gives you muscle memory because again, when you get into this historic, this hysteria stage, have you noticed something in the last week or so? How bullish everybody else is? How bullish everybody is? And we only talk about the bullishness. I try to bring in some of the bearishness into the kind of temper of expectations but you take that and rush it up to 100 when you get into the next bull run.  Bitcoin will never go down. Diamond hands. Hold forever. Never sell. And a million dollar Bitcoin coming. Guarantee. I can almost guarantee you're gonna hear that. Now price predictions, I have no idea. And it's up to you to decide what you think is best for you. But I personally think that the technology has not caught up to Bitcoin for a mass adoption for everybody to use it and to maintain the massive price appreciation we're gonna see. I just don't see it. And I was wrong on a recession this year and I was wrong on September. I called it's a September. It didn't happen. So, you know, no listen to me. That sounds good all the time. Keep the chat clean, please. Do your best. Thank you, mods, for doing what you do. I appreciate you guys. Hello, Mark. Wish coin you like most that I have, Excel, AMP or Spotlight, AMP. I had Tyler on, nice guy. It's a great project. See how it works out. Is Carano good? Carano is great. Especially with midnight coming in. Apparently it's going to be some kind of like midnight and their token dust and that'll be like some kind of privacy coin that they're working on. And if you're on the DNews Steakful because we have our Steakful for Carano we'll work diligently to give you that airdrop whenever they create that token and make it work. Rob, how rich you want to become? I'm already there. I don't, more money is not gonna change my life at all. I mean, that's not true.   It'll change my kids' lives and my grandkids' lives probably to a point. But there's only so many real estate properties that you can buy. There's only so many indoor pools you can buy. There's so many 2018 Dodge Grand Caravan that you can buy. I roll that deep right now. And I don't really see it. I think the only thing it'll change is the more amount that I actually probably give to charities. That's about it. Big protectors, great charity here in Puerto Rico. And also Amigos de la San Amalas and Caza PR. Those types, those three right there, probably, I know. I know me and my wife. That's good. That's probably about it. What about Apex? Oh, we call, we call, we talk about this. Apex is gonna do great, especially with the gaming sector. How old are you? I'm pretty old. I mean, if you can see this beard is not a touch of darkness in it. It's all white. Where are you? I'm in Puerto Rico. I like the nanger. I like the ledger now too. It's just, I just find that the tangent I think is gonna be great for the noobs. And that's why I'm trying to get them to do it. I just want them to do cold storage before they make my screw up mistakes, which would be leaving on Voyager, leaving on Celsius, believe those people and then get screwed over like we all did. Like myself, health and poor. I made a lot of decisions because soon I have only $700 in it. Holy smokes. Good for you, man. $700 in, 25K hour. Excellent job. Ethiopia. Yeah, so I know this is a lot. I still use ledger, but I have second thoughts. I have second thoughts, but I've had the CTO on from ledger. A gentleman from France, smart guy, nice guy, made a lot of sense. I know that we hate the fact that now they can for a fee, mind you, $10, they can split up your mnemonic phrase and it goes to three different companies. Ledger being one of them and it pulls out.  Well, it is.  But I thought about it. I'm like, it's not a bad idea actually because that's revenue for them and they can make updates. And maybe we can actually get on with that stacks ledger and actually produce that so people can actually buy it. And if you don't want it, they don't split up your private keys. So I'm like, it's a win-win. And but people will always say that now that's not how it is. If they can do it, then they can screw you and they can get it. But I don't think it's gonna be the end all be all. But who knows?  And also DAP radar just became one of their node operators. So on top of Google who's, excuse me, Validator. Google is one of their enterprise validators and now DAP radar is in the running as well. I thought it was pretty interesting. It's like these crypto companies all coming together. Like Cardano is teaming up with Polkadot and Polygon and near are coming together to make a faster layer two solution for a finality for Ethereum. I'm like, I take a look at these things. I'm like, this is how it should be. Like there's competition but they can still work together to make a better product. And that's what I like to see. And you'll see that quality attracts quality I think. I still a little dash. And nothing wrong with that. Probably go up to later, Pat. That's funny. That's funny, Bobby. Okay. Let's see what else we've got. 49 minutes and my back's still on a little bit but I'm okay. Favorite ISO 2002 Ducoyne XRP, you believe it is? So, yeah. Which maybe that's the chosen one for Elon Musk. All the rails and payments for X or what was called Twitter. Yeah, I need to. You don't have to. But maybe the community would appreciate a bit of how to migrate Matic to pull. I don't believe you have to do that. Let me take a look. I remember we talked about this. I guess I was wrong. Let's take a look. That's my thing of something else. How to make our Matic tokens to pull upgrade. Pull tokens be migrated to a one-to-one ratio from existing Matic, well, Matic tokens by using a migration project. Since all Matic tokens are gonna be incompatible. Sure, I'll do a video. Must've been something else I've read. Great question. I've heard guys talk a lot about SWE. Do you think it really kills soul at all this run? Anything's possible. I don't know. Guys, the team from SWE over in Korean Blockchain Week. Real good guys. And the project looks pretty great. As far as TPS, it's up there. It's up there with Solana and Near. So it could be. But again, it's just, we'll see who actually adopts it and how far it can go. It's kind of difficult to say because now we're getting crowded with a lot of these later ones. Asus is here. Asus, I got a funny story. So today I went to the acupuncturist here in Puerto Rico.  And I'm like, oh, I'm from Texas. They go, that's why, because you have a Mexican accent. I was like, oh, I didn't know I had a Mexican accent. Of course, I was speaking Spanish. So I'm like, I guess I do. Cause they're like, yeah, we know you're not from here. I was like, ah, all right. Asus, if you don't know, formally of Classy Games does a great job with everything that's going on in web three and blockchain gaming. And that's the guy. It's always, it's always him, Kagey, Johnny Hussle and Stash, when I need to know about all the new stuff, just follow those guys. Always good. And of course they called every single call that they had so far for the gaming has nailed it. I have 43,000 doge coins, is that probable? It will be Rocky, it will be. So doge coin says, by default, it doesn't ledger a software wall cause you have to log on to access your money. You have to sign transactions and you have to do it that way. But there's, it's air gapped. It's a cold storage device because it's not a hot wall which means it's not always on the internet. So it'd be the same thing with like, with like this, like when I want to send a transaction, I have to use the app on the phone and I have to tap this to authorize the transaction. So at some point you're gonna have to interact with the internet to make it actually work, but it's not on all the time like say, like your MetaMask wall or some other kind of wall like that. Hmm, Jay says, hey Rob, what would you advise any friends interested in altcoins at this point? Ah, I've learned my lesson on this one. You can try to give advice to people, but it's a losing battle and they're gonna say, what's this next great one? What's this great one?  And these days, I just tell, if I'm gonna tell anybody anything I say like this, look crypto, Bitcoin is the safest, is the safest asset and the most volatile asset class you can get. And it'll probably go up, it's gonna take some time. And this is why I talk about that. Altcoins, I say, you can make massive gains or you could lose everything. One of those two things is usually gonna happen. So if you lose everything, don't come crying to me. And that's pretty much what I say. Whereas before I like try to like get them into it. Now I'm just like, eh, do it. Good luck and go from there. Yeah, even my family. Yeah, open source. Yeah, ledgers, they're moving. And this is the thing, people are complaining about ledger fat. They go, why aren't you open source? Why aren't you open source? And they'd say like, well, we don't want to open up everything because that exposes us to hackers. Now they go into open source and people are like, why are you doing that? Because you're exposing yourself to hackers. So it's like, I don't know. Ah, good point. Rob, please don't you have to be careful which link you use for that video. The address could be fake. Yeah, there's so many different fakes out there. That's why I gotta do it myself. Let's just take a look here. Alley gone. I could have sworn you didn't have to. I'll find out later. Okay. What did I miss? And Cue, they told me to shush because I had an accent, American accent that gave me cheaper stuff. Yeah. Is it in Texas, in Mexico or the same? No. There's a big difference between going to Austin and say, what is? Mr. Mister says, Rob, is Puerto Rico tax haven safe? You can minimize taxes, but you're gonna always pay taxes. There's a video I did. It's called, All My Mistakes from Moving to Puerto Rico, One Year After. And you can check that out. Just type in digital asset news Puerto Rico. Shoot, the first one that comes up. Ken Pazza says, I wanna know if Georgia asked you to fight in this dumb crypto fight. No, nobody asked me. Thank God. Because first of all, I'm at that point where I'm like, I just wanna be healthy. I don't need to do any of that stuff. I know Crypto Crows fighting, good for him.  Best of luck, but no. And these last like a month and a half, I could barely even walk. So, now, good luck to all those guys. It's better. Exactly. Not your dad. Bitcoin is ripping now back up to 37.5. I think that's it guys. I think we're coming up in an hour. This is a long time. Hey, we did it. I did it. This is my new time frame. Pretty happy about this. And lastly, military days are, yeah. Good eight years or so. So, that's it for today. So, look, you liked today's video. Give it a thumbs up. Consider subscribing. Let me talk about his time sensitive. That's it for today. Thanks so much. Looks like the dog's having a good time. And we'll see you guys on the next one. Thanks for stopping by. I do appreciate it. Adios.


My research is about how Dutch entrepreneurs are adapting their business models to cope with the corona crisis and, more importantly, what they are making to be resilient after the crisis. The most important finding is that in order to help entrepreneurs, public agencies really need to provide practical advice to these entrepreneurs that they can implement next day with immediate impact on their business models. The impact of my research is that it really invites everyone, public agencies, entrepreneurs and government, to think about how can we really help entrepreneurs and think of alternative ways. For example, how can we provide mass-terrorized advice to entrepreneurs that is suitable to their needs. There are two next steps. The first one is to develop the website Colbebray. This is a self-help desk that was developed as part of this study. The second is to start a new research about collaboration among micro and small enterprises in the Netherlands so that we get a better understanding of how they adapt to a crisis.