Hey guys, it's MJ the student's actually and in this video. I'm gonna show you this really cute little website I came on to called wheel of dog Doggie or dog. I don't know how you pronounce it yet, but what it is you choose how many coins you want to bet What your chance is and how much you will win so the minimum that you can win has to be two dogs so I have Because being an actually and very risk adverse of matters highest possible But which means if I lose I lose Everything they lose everything. So anyway, I just I just won this so let's Let's put this as 40 and now how how much can I increase my odds? I can increase it by just a little bit more. Okay, let's spin. Let's spin. We are spinning. We are spinning Whoo, and a one. Okay, let's spin again.  Let's come. Let's come. What's happening here? Whoo, okay, look at that. I'm just So this is how you can make Make dogs online Whoa, that was a close call. Okay, that was a close call. Okay. No wait, let's let's make this interesting. Okay now Let's put it as 52 and now let's make it 95. Oh, no make it 94 0.5 0.7. Okay, 94.7. That's actually a name of a radio show here in South Africa Okay, let's go. Yeah, I won. Okay, let's see what happens. Oh, I Won again. Oh, look at me. I'm winning. Oh Oh No, did I lose? No, that is that is rubbish. No Did I lose? Oh, no, that is that's absolutely terrible. Okay. Well, don't worry. Don't worry like a like You know that whole thing winners don't know when to stop Let's let's try it again. So this is 50. How much do I want to win 90? We can make it 93 0.7 you can make it 94 Let's try 94.7 again. Okay, cool. Well the last time this this destroyed me What I Had like a I had a 94 percent chance of winning though.  So I have okay. I'll put it in so I have 500 dogs but what I'll do is share this video and Just for fun the first five people to share the video and post me the dog chain address I will give you guys a hundred dog coin just for doing that And that's much better than you know that wheel thing eating it all up At least you guys get to get to have fun with it and then you're you can go to that little wheel Where is it over there? Wait, can I actually bet this last bit Whoo, ooh, can I win it all back? Can I win it all back? Let's let's go big Let's go big two eight eight one No, no, no, no, no, no, no, okay. Let's see Oh, no, it has to have a minimum amount of wonder. Oh Oh, this is gonna be such a great classic fun, but what we can't we do it with this last one? With this last one. We've got we've got six left. We've got six left. Yeah Where's the fun? Let's see if we can make it all back Let's see. Oh, no, we have to because the minimum. Yeah, let's just go 50 50 50 50 50.  Look who's back in business. Okay. Um, how much should we bet? Okay, let's make it 20.3 um The chance should we make it 75 yeah, I think 75 is a nice number Oh, okay 70 Anyway, uh, thanks for watching this terrible video Like I said, I do have some dog coins that I am going to be giving away. So the first The first five people to share this video and comment with that We'll get some dog coin And the reason why I want you guys to share it is I am going to be making a whole bunch of videos explaining bitcoin Explaining how cryptocurrencies work. It's going to be a lot of fun So make sure to subscribe and I'm going to be taking on from a bit of an actuarial slant So it's going to be pretty cool.  Cheers


Top Tips for Teaching English in Europe For many people looking to teach English abroad, Europe is the number one dream destination. Whether your dreams involve the romance of Paris, the fine art of Florence, or the night life of Barcelona, the good news is there are plenty of teaching jobs available, even if you have no previous experience. If you are a native speaker of English, there is really nothing standing in your way. If you want to be a successful teacher living and working in Europe, here are the key things you need to know. Get TEFL certified. As mentioned, you don't need any previous experience to get a job teaching English in Europe, but you will need a TEFL certification. As competition for teaching jobs in most countries is increasing year on year, the vast majority of reputable employers will now only seriously consider those who have made the effort to complete a certified teacher training course. Completing a TEFL course will also give you the skills you need to feel confident in the classroom and to provide a high quality education for your students. At HIDTT we offer our four week in class TEFL certification course in many great locations across Europe. We also offer a range of online TEFL courses that are also welcomed by European employers. Prepare to interview in person. Unlike some other regions of the world, employers across Europe tend to interview their prospective teachers in person. Obviously, this means you will have to be prepared to leave home without a guaranteed job in place. Although this might sound a little daunting, the reality is that most people are able to secure a teaching position soon after arrival as the demand is very high in many areas. If you consider that the majority of people only teach for one to two years, it is no surprise that the high turnover of teaching staff ensures there are always plenty of vacancies, particularly during the peak hiring seasons. There are a few exceptions to this rule. Government-run programs that recruit teachers to work in public schools generally hire in advance from your home country. The TAPF program in France, the Cultural Ambassadors program in Spain, and the Central European Teaching Program in Hungary are all great options in this category. You may also find jobs advertised online in advance in countries such as Russia and Turkey. If you choose HIDTT for your TEFL training you will receive extensive post-course help with all aspects of the job hunting process. Be aware of each country's requirements. Although teaching experience is generally not necessary in Europe, some countries do have other requirements. In certain countries, you will need a college degree in any subject to work as an English teacher. However, while this is the case for countries such as France and Turkey, there are many others where it is not a requirement, such as the Czech Republic, Italy, and Spain. The other major requirement to consider is a visa. Anyone with an EU passport will have little to worry about as they can legally live and work anywhere in the region. Unfortunately, things are not quite as simple for non-EU citizens. In countries such as Spain and Italy, you can apply for a student visa which also allows you to work a set number of hours a week. Elsewhere it is common for language schools to sponsor you for a work visa or you can apply for a work visa as an independent contractor. Just be aware that an individual country's requirements can change at any time so we advise that you check with an embassy or consulate online or in person for the most up-to-date information. Make multiple job applications and even accept more than one offer. If you have a good quality TEFL certification, don't make the mistake of accepting the first job offer that comes your way. If you apply for as many teaching positions as possible, you can expect to receive multiple offers which will allow you to choose the one that suits you best. In fact, you don't have to simply work for one employer. It is common practice for EFL teachers and you're up to work for more than one language school at the same time. The main advantage of this scenario is that you can pick and choose the lessons that you want to teach. Certain times of the day an or different age groups may well suit you better than others. Take on private lessons in your free time. Another common practice for EFL teachers in Europe is to teach private lessons outside of school hours. This is a great way to top up your earnings and it can even lead to a full-time job where you can decide exactly what hours you want to teach. It will probably require a bit of hard work and patience to build up a client base, but the greater level of flexibility and higher hourly rate that comes with private tutoring usually makes it worth the effort. Experience of teaching when the one students can also help you find employment working as an online tutor, which is an ever-growing field that you can exploit from anywhere in the world. As teaching English in Europe will likely involve a long flight and no paycheck for at least a month, it is an adventure that also needs to be considered from a financial point of view. Once you start earning, your income should be enough to cover all the basic expenses such as rent, transport, and food, as well as enough extra to fund a couple of nights a week on the town and travel on the weekends. However, you will still need to budget enough funds to get you through to that first paycheck. Realistically, you should arrive in Europe with enough funds to support yourself for one to two months. This sum could be anywhere from $1,500, $2,500 US dollars, excluding airfare, depending on where you choose to look for work. Obviously, accommodation and other expenses will be higher in major cities such as Paris or Rome in comparison to a small town in the Czech Republic. Pick and choose your clients wisely. Although some teachers will work from within the same school or institute throughout the week, many teachers in Europe will spend a significant amount of time commuting to various lessons around town. While traveling from A to B in a foreign city might be fun at first, spending 30 minutes getting to a 45-minute lesson several times a day will soon get tiresome. Just remember that you do not have to accept every student that your language school offers you. If possible you should ensure that your students are all in the same vicinity so you can maximize the amount of free time you have away from the classroom. Yes, maximize your free time. Although you will need to work hard to ensure you have enough cash to enjoy your free time away from the classroom, don't forget the main reasons why you chose to teach English in Europe in the first place. For most people, it is to explore the countries and culture that make this region so unique. As the distances are relatively small between countries and major cities, it is quick and easy to visit virtually any of your dream destinations in Europe over a weekend. With this in mind, you might want to say no to that 4 p.m. class on a Friday so you can get a head start on your latest adventure. Are you ready to teach English in Europe? Speak with an ITTT advisor today to put together your personal plan for teaching English abroad. Send us an email or call us toll-free at 1-800-490-0531 to speak with an ITTT advisor today.


Welcome to the show, it's me, John Park, and it is time for another JP's Product Pick of the Week. Here we are. I want to say thank you to everyone for stopping by over in the YouTube chat and in our Discord chat if you are somewhere else and you're wondering where the chatting is. Head to our Discord. You can go to adafru.it slash discord and you'll get an instant invite and you can join in on the live broadcast chat channel. So hello, Mike P, Rich, Sad, Todd, Bot, Zarnlin, OK, Yaron, Jim Hendrickson, Scott, D, B, me up. I never get that name right. And over on YouTube we've got Tackle the World and Antonina Makarova, welcome. And there's probably others and I'm sorry if I didn't call you out, but thanks for coming by. If you want to head over to the page where this week's Product Pick lives, head right there. You can go to this QR code. You can go to this URL. You will see that this very show is happening in a little window inside of the product page and the reason you'll want to be there is for the huge discount that's available right now during the live stream only. That discount just dematerializes after the live stream so you want to fill up your cart with good stuff and get some of this week's Product Pick if it's something you like. I'm not going to force anyone.  So usually what I like to do is go and check out the new Product Pick video that LeMore did for the Product Pick. There wasn't one for this. This was a revision of a board and I don't think there ever was an original. I couldn't find it and I asked around and it just doesn't appear to exist.  This is it right here. It is the USB LiPo LiPoly Lithium Ion Battery Charger. So this is what you need if you want to charge up these types of batteries, right? So we've got a lot of different little batteries, especially some of these bigger ones. You might want a dedicated charger. Some of them you can charge with something like a feather that has a charging circuit. But for other battery projects you need some way to charge these up and this one is terrific. It can charge at up to one amp, usually I think it defaults at 500 milliamp charge rate and one of the great things about this is that has the, let me get the number on it right, what's the, yeah it's the microchip MCP73833 charging management chip on there and what that means is that it charges in three stages. It does a preconditioning, it does a fast charge and then it does a trickle charge. So this is a nice sophisticated charger and it has some pretty great features too. So you'll notice we have these JST connectors at the bottom so you can plug in your battery right down here. So that's the battery you're planning to charge. It has a mini USB which is actually, I love these. I don't know why we ever went to micro. Of course C is terrific too but here is mini USB which is a bigger, bigger than micro as you can imagine and easier to plug it in the right way the first time. So you see here we can charge from USB there. It tells us that we have power with a little red LED here and then this is indicator that is yellow right now that tells me this is charging and then when it gets to a full charge and it's just doing the trickle that LED turns off and we instead get the done or green LED to light up. Now we also have some other extra cool features on here.   So we can plug something in. It will run off of, I think it's whichever is greater if it's the USB or the battery but when you unplug USB you're still, the load is still running. So this is a nice way to build a type of device that allows you to just plug it in, charge it when you need to and then unplug and be on the go. Now for connecting up to devices you can use this load JST but you can also use some of the breakouts that we have here. In fact, let me get a little closer to the board and refocus, oh I passed it, pretty good right there. That looks good. So let me find a little something to point with here. So you'll see here on the left side we have breakouts for the load. So you can plug in one of these little connectors that comes with it. We have a little JST cable, in fact if I show you a little product photo here you'll see. That's what comes with it. So you can plug in that JST connector cable to those load breakouts. We also have breakouts for the status LEDs which I'll show you those are low by default so you'll hook up the cathode side of an LED to each of those, it's the charge and the done and then to power which I would use this plus on the DC inside of it. And then we have a battery connector too. So if you have a battery that you want to have permanently in a project and you don't feel like connecting it in through this JST if you want to cut wires and solder it in you could use that as well. It's pretty nice and compact and you can imagine depending on the type of battery you're using you can make a little holder for it or use some double stick foam tape to connect things up. So something like this could end up being the little package that you have to plug and play with. Now let me show you a little demo of one in action. So here is one where I've soldered on the connector for load so I can charge something up or power something rather. So here I have a circuit playground express and you'll see if I plug a battery in over here let me zoom out just a bit I don't trust the autofocus so I've got to refocus that there we go. So if I have a battery plugged in you'll see that immediately powers up the device so I have a circuit python or circuit playground express running over here. Now if I want to start charging this I can just plug in and it won't interrupt anything you can see the power still running over here there's no hiccups there and now we are driving this either off of available battery power or over the USB it's never going to turn that device off and then on this one I've actually added some headers just to make it easy to play around with external LED. So let me let's unplug this for a second so you'll see here I've got a funny little sort of circuit sculpture of a couple of LEDs and a resistor running to that positive DC power so you can see here I've now extended essentially the charge LED and the done LED I think I have a battery that might be close to fully charged so we should see this one oh what have I done it's it's struggling I think that battery is actually a little loose okay you can see that one go to done so it's now in trickle charge mode the little green LED there as well as my extended LED there is letting me know and the reason you might do this is if you have mounted this inside of a case for a sort of semi-permanent installation then you might want to know on the outside if you have completed your charge or not and then you can unplug and be on the go so let's see let's head on over to the product page here to check it out and these are normally $12.50 let's reload we are now at $6.25 maximum per customer you don't need a coupon code or anything you can just head right here throw it in your cart off you go remember get those before the show is done because then the price will return to normal yeah by the way someone noticed see Grover noticed that I didn't have any yellow LEDs so I put some capton tape over a white LED make make yellow gave me that nice amber thanks for noticing I love amber LEDs are the best LEDs so here you can see this is the product page it talks about some of this the information specifications for this so yes a 500 milliamp charge current which is adjustable using where'd it go here unplug one of these using the little slot there we have we can plug in a you can solder in an LED I think it's a 2k sorry resistor can plug in a resistor there I think it's 2k by default if you plug in a 1k resistor then it will allow up to the full amp and then if you put in bigger resistors you can drop it down to 100 milliamps at the bottom end and the reason you'd want to do that is if you go up to a higher charging current on a battery that allows it so check the battery stats and it's best to use batteries from Adafruit for this or know really well that you're getting the same kind because some especially ones who buy an Amazon may have the polarity reversed on that little JST connector and you don't use those that can be bad but if you look at our batteries you will see some will say that they have a maximum charge current of let's say 1200 milliamps and that's fine to go up to the full one amp on this some will say that they require lower and then you probably want to leave it alone as you go up to higher charge currents you may reduce the life of the battery but of course you're charging it faster so this one here for example this is a 2000 milliamp hour battery I think you can charge this in about four hours with a 500 milliamp current so you could reduce that I don't know if it scales linearly I don't know if it goes in half if you go up to the the one amp but when it gets to that fast charge portion of it it'll be dumping more power into it let's see it also mentions the different connectors you have there's also a support for a thermistor so we just have a resistor soldered in there right now but if you had either a battery that had a thermistor to measure temperature built into it and a separate wire you could plug that in or you could potentially run an external thermistor onto your battery to allow it to monitor temperature and I believe it in the in the chip data sheet which we'll take a look at it it'll let you know at what temperature it will shut it down let's see that's about it yes so then if we click on this little data sheet eagle cat pcb files fritzing objects here in the tutorial you can then click on the data sheet and you'll see here this is the microchip mcp7 sorry 73833 and they mention the typical applications you'll find this chip inside of cell phones cameras bluetooth headsets usb chargers and so on so it's a whole management chip there's no microcontroller on here other than this chip itself this chip does all of the management of the charging and it's a good one uh so let's see any questions over in our discord where did my uh i've lost my discord window i have there you are let me bring that up let's see um i have lots of problems with the connectors on lipo batteries says rich said yeah so you could potentially depending on on the type of thing you're doing you could say the heck with it with these cut that one at a time don't don't bridge that uh and solder those into the battery um pins on the board there so you're not dealing with that you also make things a little more compact than depending on what you're trying to build this into uh let's see yeah it's an early product 25 is it 259 i think that's right yeah 259 so this is version 1.2 so there was a version 1.0 uh that was uh discontinued this was revised so this one goes back a ways i'm not sure when the 1.2 came out actually that could be part of the problem why i couldn't find a a new new new video uh let's see uh any limits on the incoming power pads i believe six volts uh it's is is the maximum yeah it's designed for um essentially the five volts of usb but it can be a little higher so i believe the limit on this is um the uh six volts which is i think indicated in the pinout of the um product page as well as here on the data sheet so you can check there and see what the the maximum is uh yeah seven volts is the maximum on the chip that may be a little lower or we might just be um helping you be cautious about it here so uh yes but it is designed for for uh usb as the incoming thank you for the question dave smith uh all right well i think that's going to do it this is um my favorite little charger for keeping these types of batteries going i have a couple of them around the workshop i keep batteries plugged into them and they are also great for integrating into a project where you want to have power recharging uh mobile usb to plug it in and keep the thing topped off or just run it directly off of the usb when the battery is low uh so there it is that is the usb lipo battery charger and i put a hanger on in advance this time how about that uh all right that's going to do it for this week thank you everybody so much i will see you next time bye bye


So I'm from the National Institute of Environmental Health Sciences and I'm going to give you just a really brief run through of the NIH roadmap epitomics program, which in many ways is kind of the complementary program to encode. So as many of you know, there's lots of different epitomic changes that have been implicated in many human diseases. A lot of these changes occur through normal developmental processes and there's also lots of external influences and environmental exposures that can impact the epigenome as well. So the NIH epitomics roadmap program is really a comprehensive program, a common fund program that has a lot of different complementary components. It's really trying to accelerate the understanding of epitomics in human health and disease through a lot of different new research tools, data sets, and infrastructure. And this is listing a lot of the different components of the roadmap epitomics program. So there is a large research component. Those are mostly R01 grants that are focused on different disease outcomes. There's a discovery of novel epitomic marks. There's a computational analysis component. There's also a technology development component that includes a lot of in vivo epigenomic imaging. And then the reference epigenome mapping consortium is kind of the public resource of the human epigenomics data. And this has really leveraged a pipeline that includes a lot of next generation sequencing technologies to map DNA methylation, histone modifications, chromatin accessibility, and RNA transcripts. And I have down there, I've listed the different mapping center components and the coordination center. So the mapping centers have made epigenomic profiles of many different primary cells and tissues. And this includes the heart, the GI tract, the lung, many brain components, many blood components. And this is in both adult and fetal tissues. And they've also looked a lot of different derived embryonic stem cells as well. And these areas that were selected were carefully trying to represent as many of the normal counterparts of many tissues and organ systems that are frequently involved in human disease. So from these studies, many questions have now been answered about how different human cell types and tissues do differ epigenetically. And there's lots of uses, of course, of this epigenomic information. And I know many of you are using it in many different ways. And it's been encouraging at ASHG to see a lot of uses of the roadmap data. I just wanted to highlight a couple that I think do complement especially the encode use of the data. And one is the marking of functional genomic elements. So along with encode, the roadmap data has really assisted in annotating a lot of different areas of the genome and different cell types. And then the other one is interpreting GWAS hits. And Mike already kind of alluded to this. But we've learned that a lot of the GWAS hits are really in coding regions, non-coding regions, regulatory regions rather, and that a lot of them are in or near enhancer or promoter elements. And that's really impacted the types of functional follow-up studies that a lot of investigators have used and have focused on in recent years in order to interpret the GWAS data. And then I also just wanted to mention that it's been used in recent years to try to better identify different cell types that are involved in particular diseases. So for this particular example in this paper, they were able to show that a number of different immune cells were implicated in Crohn's disease. And so finally, I just wanted to mention that we had a big issue of nature earlier this year that had a lot of different publications, including an integrative analysis reference aptidgenome paper. And I really encourage you to take a look at this issue if you haven't already. It kind of gives you a good idea of the breadth and the depth of this program, and there were a number of other publications in nature-associated journals as well. With that, thank you.