Welcome to the party, here in the room... We have a live instrument from 2010 to 2020. Live from our outdoor studio here in Belen. Last year, we could celebrate the coolest tool of all at Wikimedia in Stockholm. This year, we cannot do that, and that's why we're doing it now. with you from home all around the world and here in Berlin. We're here today to celebrate the work of an amazing technical community at Wikimedia. Tools are super important on the Wikimedia project, and so are the many volunteer developers who are creating tools, for example, to enhance the editing experience, improve the quality of the content, visualize data, and so much more. A couple of weeks ago, the Cools Tool Academy asked for nominations for your favorite tools. Thank you so much for all the nominations. Today, we are awarding tools, but it's not only about the tools, it's about the people behind the tools, the developers who develop the tools, but also the users of tools who test the software, who use it, who report bugs, and much more. Thank you all so much. Let's get started. Let's go through the different categories together. And the first category is editor. Our winner for this category is auto-wiki browser. This is a semi-automated editor that allows you to perform all of the repetitive tasks quicker and easier. Music More about why this tool is so cool and how it works. Hello, folks. What's going on? So today, I want to talk to you about a desktop piece of software that you can use to edit Wikimedia. It's called Auto-Wiki Browser. So Auto-Wiki Browser works for Windows and Linux. So if you are a Lemp Mac user, you can use this alternative right here. The cool thing about Auto-Wiki Browser is that it allows you to do a bunch of edits in no time. For instance, if you want to edit all the articles in a category, you can use Auto-Wiki Browser among other solutions. To be able to use Auto-Wiki Browser, you check the table right here if it says that you have to request the right traded Wikibrowser, as is the case in English Wikipedia. You have first to request permission to use it. To download Auto-Wiki Browser, you go here. After you click on this link right here, you download. When you unzip your download, you click on Auto-Wiki Browser. And there you go. You have Auto-Wiki Browser on your desktop. Because I'm using it for Arabic Wikipedia, the things that are supposed to be on the right are on the left side and vice versa. So in my case, I want to move all the items in one category into another correct category. So when you first install Auto-Wiki Browser, you have to select your project from here. You add here the ISO language code for the Wikipedia you want to use. And then you log in with your account from Wikimedia. Now you can start your edits. So in this case, I will select category and I will write the name of the category I want to move from. You click Make List. And then I will click on Move More and write the category I want to move from and the category I want to move to, the correct one. And then I click on Start here and maybe add a small summary about the edit and then click Start. So as you can see, I can save the edits here. So there you go. I made four edits on few clicks. So let's see if it changes the effect. As you can see, the new category will have the items now right now. So there you go. Enjoy as possible. Okay, so the next category is actually one of my favorite categories, the newcomer category. It's for tools created by new developers or for new tools. And we are really happy to announce that this year's coolest tool award goes to... STC robots! Yay! Congratulations! So let's have a look how it works and why it is so cool. Hello everyone! ST0 Bot is a bot that generates a collection of user space reports that streamlines processes like AFC and MPP by sorting articles by Oris topics and by showing excerpts of the lead section. The bot started operating in 2020 and it has a lot of potential for providing insightful lists and summaries for many use cases and communities. Let's have a look at some of the reports that the bot compiles. On the bot user page, you can see it was called down the list of the reports that the bot is compiling with some other information about what they are and when they run for the last time. Let's look at the first one for example, the most important scripts. Here we see a list of the most important user scripts on English Wikipedia. Here's some details about how the information is compiled. This information is very useful because it's usually super hard to know how much a user script is used. So this is already very insightful information. Let's look at another one. We're going to look now at the second one with the article for creation submissions. Here we can see the report with the pending article for creation submissions, with the date and some other information that is added to the report. So here we can see it was scrolled down, a list of sections with the topics and the articles for creation that are pending submission. It was scrolled down, for example, I like the computing ones. And we can see here a list of articles with some enriched information like the class that Oris predicts the article will be. This may or may not be accurate, so check the disclaimers at the top for more information. If we look at the main page for this specific topic, we can see even more information, which is very, very useful, like the class when it was submitted, the creator and number of edits, all of the article, et cetera, and some other notes. So yeah, here we go. Very, very useful information for certain processes on the Wikis. Finally, let's look at a quote from a user of the bots reports. This tool has made it easier to find AFC submissions, new pages for MPP, articles proposed for deletion, prod AFD, good article nominations, peer review requests, et cetera, where the article subject is of my interest. The short descriptions, the excerpts. The Oris sorting helps editors find articles they are interested in. Before SD0 bot, there did not exist any tool that used the very useful Oris topic prediction service, nor one that listified articles at the various processes. AFC, AFD, et cetera, with excerpts. And that's it. Congratulations to SD0 bot. Our next category is impact. This is about tools that have a broad or deep effect on the Wikimedia projects. And our winner for this category is proofread page extension. This tool made a huge difference on Wikisource. Hi everyone. The proofread page extension is a media wiki extension that can render a book either as a column of OCR text beside a column of scanned images or broken into its logical organization such as chapters or poems by using translation. It allows for easy comparison of the text to the original digitization and it shows the text in several ways without actually duplicating the original text. The proofread page extension is at the heart of the Wikisource project. It was adopted in 2008 and has had immense impact through the years as we can see in the stats page. We dig in. We can see that there's proofreading of pages going up through the years with a huge amount of pages proofread every day. If you want to learn more about proofreading, there's a great manual on Wikisource where you can learn more about it. For example, the pages of a book go through different statuses and we can see here in the documentation that they go through proofreading in different states depending on what the editors do when they proofread the pages. There is also a great beginner's guide where it explains how to proofread for new users. It also suggests getting started with the proofread of the month. This is something that the Wikisource community does every month where they find a new work to proofread and collaborate on. You can see here the proofread of the month and if you scroll down you can also see past collections that were proofread in the past. For the current proofread of the month I check the index and the several works have already been proofread. Yellow as you remember means proofread and green means validated which means that it has been proofread by more than one user. So I found a different work to have a look at the process. You can see here the index which is a very important part and here the pages. We can choose one page to check the proofreading and here we see the actual text that was detected by the OCR and the page of the book. We will click Edit. We will see on the side the page of the book which we can move to read through it and on the left we can see the text that we have to adapt or fix in case there are problems. We have other tools we can make the layout horizontal if that's what we need and there are many other things that we could do. Once you're done proofreading the page of the book with the text that was recognized by the OCR or edited by someone you can head down you put a summary of the changes that you made and change the status of the page if it was fully proofread. For example, yellow would be putting it on the proofread status and then someone else would have to validate it or if there are problems with the page you can change it to the problematic state. Then you would publish the changes and voila, the page has been proofread. As I said before, this extension is at the heart of Wikisource and it's indispensable for the website. Congratulations to the proofread page extension for winning an award on the Impact category. Moving on to a new category, Experience. This is about tools that are especially intuitive or easy to use and our winner in this category is Listen to Wikipedia. A website that is providing different experience on the editing activity on Wikipedia. Let's have a look. Hi, thanks Lea and Brigitte for introducing. Now we are giving a 10-second music break. Do you hear this relaxing and pleasant music? This is the voice of real-time editing to Wikipedia. Each note you hear is another contribution to free knowledge. Let's try to listen to this voice more carefully. All these sweet audiovisual stimuli carry a meaning actually. Bells are additions. This one. Strings are substructions. Now you have just heard it. Green circles are anonymous edits and purple circles are bots. White circles are edits from registered users. This one right here. Bonus. You will see a blue message on the top of the screen when a new user is joined. This is great luck if you ever saw it. Don't forget to welcome them by adding a note to their talk pages. Let's talk about the possible settings of the software. When we scroll down, we will see a list of recent changes that we have just listened to. Right below, there are some settings to hide some elements of the page. For example, we can hide recent changes console if you like to. Next, we have reached the language selection section. We can listen Wikipedia's of some other languages than English. Also, we can listen to wiki data too. By the way, I bet it will be crazy fast music. Let's check. As expected. The last option that listened to Wikipedia software gave us is the ability to filter by tags in edit summary. I personally find this super helpful when it comes to follow-up change logs of an edit aton. If you are a facilitator of an edit aton, tell everyone to include a tag to their edit summaries and listen to their changes from listen to Wikipedia. Don't forget to grab your popcorn though. Thanks to this super cool project, every edit has a voice in the roar. Remember that every time you make an edit, you release a note to the air. Make sure that you visit atlisten.headnote.com and try this cool tool art. Now we are back to Bridges and Leia. Okay, now we are coming to the category reusable for tools that serve many wikis and projects. We are really happy to announce Global User Page as the winner. Congratulations. Let's have a look why this tool is so amazing and how it works. Hi folks. Global User Page is a media wiki extension that enables global user pages on a wiki form. By default, on each wiki you log in, you can create a user page, a different one that is. This extension allows you to have one single user page that is shared across wikis automatically. At wikimedia, users with an account can create a user page for all wikimedia projects on meta wiki. As you can see in the documentation. Now, let's try it out for my account. I have this account where on ES wiki I have my small user page and for example, on Catalan wikipedia I do not have a user page. I do not want to go to each wiki and create a different user page so I want to create a global user page. For that, I will go to meta wiki. As you can see, we are on meta wiki and now you can see by the red link that I do not have a user page on this wiki, so let's create that one. You'll see the page doesn't exist. I'm going to click create. And here, as you can see, we have a banner saying that we're about to create a global user page, which is exactly what we wanted. There are some links to documentation, which is great. And now, let's create our awesome user page. Cool, this is exactly what I wanted. Let's publish the page. Here we go. Now we have a user page on meta, as you can see. So now, to check that it worked, let's go to German wikipedia, for example, which I haven't been there before. I'll click on my username. And here we go, the user page that we just created is a meta and a link to the global user page. We can do the same thing on Italian wikipedia, for example. And if we check Spanish wikipedia, our existing user page is still the same. To finalize, let's hear some quotes from some users. Global user page is a key and essential feature for the global wiki community. It allows users to keep their user pages in sync, reduces friction and makes coordination across wikis a lot easier. And another user said, I can still remember how it was before global user page became available in 2015. Maintaining user pages across wikis was cumbersome, and mine definitely got out of sync. So congratulations to global user page and let's see the next one. And now let's discover a new category, quality. This is about tools that improve accuracy or completeness of the content or help detecting vandalism. And the winner for this category is abuse filter. You probably know about it, but let's have a look at how cool it is. Hello. I am Fubar4004 and I'd like to complain about abuse filter. This media wiki extension allows to define criteria for edits. And when the criteria match, then an automated reaction happens, which you also defined. For example, your wiki can have a filter which does not allow anonymous users to add external links to a page, or you could block users who try to remove more than 2000 characters from a page. Abuse filter is enabled on a number of wiki media wikis. Are you a vandal, just like me? I love making bad edits on the wikis, but abuse filter made my life harder while it allows you to spend more time on editing content and less time on reverting me. Here is how it works. Global filters are automatically enabled on smaller and medium wiki media wikis. And for your own wiki, you can set up some local filters. Here you can see an example. Now, when I try to make a bad edit, I am stopped by abuse filter. With the help of abuse filter, you reduced my vandalism by 90%. If you are a smaller wiki community, check out the small wiki toolkit starter kit on Meta and learn how you can use abuse filter to stop me. Abuse filter. Congratulations for supporting reliable free knowledge. So we are now coming to the developer category. Tools that primarily serve developers. And I am really happy to announce that PiWikiBots is the winner of this year's Color Student Award. Congratulations! PiWikiBots is a Python library and a script collection supported by a great community. Let's look more into it, what makes the tools so cool and what you can use it for. Hi, everyone. Let's talk about PiWikiBot. PiWikiBot is a Python library and collection of scripts that automate work on media wiki websites. Originally designed for Wikipedia, it is now used throughout the Wikimedia Foundation's projects and on many other wikis. PiWikiBot is a tool for developers, and with it, you can create your own scripts as shown in the documentation. PiWikiBot also comes with many different scripts that you can use that are already built and are very, very useful. You can see them go into the scripts page on the menu and you can run them with this command. Now, let's quickly try PiWikiBot. First, we need to install it. There are multiple options for trying PiWikiBot. You can try it on POS, which is a Wikimedia service that offers Python notebooks. You can install it on your computer and run it. Or you can run it on Toolforge on the Wikimedia cloud services. For our demo, let's build a local script. I've installed PiWikiBot on my own computer, and now let's switch to it. Here's a folder where I've installed PiWikiBot locally with the latest stable version. I've already installed the needed dependencies, generated the user files with my credentials and the projects that I'm interested in, and logged in to my account on Wikimedia. Next, I've written a very small script that we're going to try, based on the example on the wiki. Here, we imported PiWikiBot. Here, we create a site for Spanish Wikipedia, which is where I want to run my script. We grab my user page, and then we replace the text of the page, changing hola with adios. After that, we save the page and give it a summary. Let's run our script. Now, when we run the script, we can see the user page was saved, and if we go to it, from the previous contents that said hola, now we have our new edit, adios. The other way we mentioned of running PiWikiBot is by using the existing scripts. In the case of replacing content, there's already a script that can help us with it. Here, you can see how it can run in place.py, and we're going to run it with Python, by wiki.py, replace, and then we're going to tell it the page that we're going to replace some content on. In our case, my user page. We're going to replace the other way around, adios with hola. So, we're going to run it. Here, we can see it's asking us what the summary of the edit is going to be. It's giving me a nice translated summary. I'm just going to hit enter. It fetched the page from Wikipedia, and it's showing me a diff of the edit that it's going to do. Looks great. So, I'm going to tell it yes to accept the changes. And as you can see, it did the edit. Now, if we head back to my user page and refresh again, we can see the contents are back with the last script run that we did. Let's read some quotes from PiWikiBot users. The value of PiWikiBot is incredible. And the script's available and a strong community behind it. It makes bot development much more accessible for folks with less programming skills. And another one. PiWikiBot is a key framework for developing bots for the Wikimedia projects or any MediaWikiWiki. Its impact is huge. It makes bot development much easier, and it comes with scripts for a variety of tasks. It has an active developer community with a mailing list, IRC channel, and more. It has more than 160 contributors to the code base. Okay, we are coming to our next category, Diversity, for tools that help to include a variety of languages, people, cultures, etc. And this year's winner in the category, Diversity is Lingua Libre. Congratulations. Lingua Libre is an amazing tool. And with Lingua Libre, you can record and upload words and a variety of languages to Wikimedia Commons and use them in other Wikis, like Wikidata and also Wiktionary. Lingua Libre is indeed awesome. Its goal is to gather as many audio files as possible to collect words and phrases in plenty of different languages. It's multilingual, it's cross-weakie, it's uploading files on Commons on your behalf and also improving Wiktionaries and even Wikidata. Lingua Libre is bringing more visibility to plenty of underserved languages. Let's have a look at how it works and how you can contribute. So, I want to start recording my voice. First of all, I need to make a test to try on my microphone. Coolest tool award. Alright. The next step is to give a bit of information about myself. It's important that the contributor indicates the languages that they speak and where they're from because we also take into account the different accents or dialects in Lingua Libre. So, I'm going to say that I speak French as a native language. Language. And I'm also going to add that I live in France because, of course, the sound of French will be pretty different if I would have learned it in Québec, for example. This list is coming from Wikidata, by the way. So, here, I can directly enter the words that I would like to pronounce. I can choose the language and I can also get inspiration from other places, for example. I can get a list. I can also have a look at things that are located nearby and I can directly pick a Wikimedia category. Here is a nice list of the most used words in French. Sounds good. Now, I'm in the Recording Studio. Whenever I'm ready, I can start clicking here and then just read the different words and the system will automatically detect when I'm done and create the fives. Je, tu, il, elle, on, nous, vous, il, elle. That's enough for now. I click on Next. The next step is to listen to the recordings again just to make sure that everything's fine. Then I can select the ones I want and I'm ready to publish on Wikimedia comments. Let's do it. My comments contributions. Indeed, this file was created. It has the title, the description, information about me, everything that people need so they can reuse the file. Oh, look, I'm on the main page now. So, the coolest tool award committee really loved this tool because it's super easy to use, as you could see. And it's supporting all of the minority languages in the world, which is pretty awesome. Thanks to everyone who contributed to the development of Lingua Libre, the community adding content to it and please record more words in your languages. Let's have a look at the tiny category. The tiny category is for tools that are either small or doing only one thing but doing it well. And the winner for the tiny category is Crop Tool. Congratulations. Crop Tool is a tool that allows you to cut or resize pictures either on Wikimedia comments or on the other Wikimedia projects. And now let's have a look at how it works. Hello, everyone. Here's Crop Tool. Crop Tool has one purpose and it's very good at it. It is a tool for cropping images in the Wikimedia comments and other websites. It supports JPEG, PNG, TIFF files and animated Git files. It can extract single pages from the JVU or PDF files for JPEG cropping. It features automatic border detection and it has login authentication with Auth. It also has other features specific to other Wiki workflows like being aware of certain templates or categories that are present in the images to make smarter decisions and appropriately edit. We can see those on the GitHub repository on the documentation there. You can see an example here with remove border, for example, or watermark. You can also see how much Crop Tool is used. It is a widely used tool on comments and if you look at the recent changes you'll see the amount of edits it has. If you want to try Crop Tool you can try the category images with watermarks as linked in the documentation page of the tool. And here you can see a bunch of images with watermarks that could use some editing which Crop Tool is great at. For example, I'm going to visit special randoming category images with watermarks with the category that we just visited and I'm going to get a random image that we will try the tool on. So I'm going to click on it now and I get this image with this very cool building. As you can see it has a watermark at the bottom. We're going to go and activate Crop Tool from the link in the documentation page and then we'll get a little wizard where we will approve the gadget to be installed in my account and once it's installed it will give us some instructions about how to refresh the page so that you can see the gadget loaded and use it. If we go to our image that we want to edit right now, we refresh and we see the link to Crop Tool is there in the corner and then we just click it it will take us to the tool where we'll have to authenticate. I was already authenticated before so I got directly to the image a little window where we can crop our image very, very straightforward. We can see some numbers up here where we can see the specific numbers for the dimensions and the cropping. We use the magic border locator in this case it just selects the full image as it is because there's no weird borders and we can then crop using the handles on the rectangle. Right now we're cropping using the free method but we can also choose to keep the aspect ratio and it will keep the same size the aspect ratio of the image for example if we wanted to crop it without changing the aspect ratio we could do that and then move it around for this one we're going to keep it as free because I don't think the aspect ratio is very important in this image right now so we'll crop it like this and then we will choose the method of cropping we'll choose the precise method and then we will click and it will crop the image we'll see a preview of the crop's image where we can inspect that everything looks as it should and then we can see if we should select overwrite or upload a new file this is kind of tricky, there's some rules so please check comments over writing existing files for the guidelines so when this is appropriate this will give you some guidance for example if we look at minor improvements one of them is removal of a watermark which is what we were doing and then if you've removed the watermark you can check this checkbox and then you'll get a nice edit summary click upload and then the edit will be performed on your behalf and successful now we can go directly to the result to see how it looks like and we can see the edited image without the watermark looks great, did a great job and you can see the new version with the edit summary that we saw before so yeah congratulations to PropTool for winning the tiny award, cheers okay we are now coming to our last category the egg beater but we hand out four tools that are unused for more than 10 years and the winner the egg beater in the category the egg beater goes to X-Tools cheers congratulations so X-Tools is a series of statistics tools and we are going to look more into that in a second and I'm handing over to the demo hello guys what's good so today I want to talk to you about a tool that has been around for a while now I'm pretty sure many of you have used it before it's called X-Tools so X-Tools allows you to do particularly two basic things it allows you to check the a user's contribution on an article but also the information and the details about an article so if you have X-Tools enabled in your account you can see a line under any article that says number of revisions and date etc so you can click full page details statistics to have more information when you click on that it takes you to a page that has all the information you want to know about the article for instance how many edits it has time based etc and you also have a list of major contributors the editors to the article so when you click on top edits or edit counter it takes you to the page that has the information about the specific user for instance this user has has a lot of edits and you can see here the projects on which the user contributes and a pie chart about the major projects in which they contribute so if you want to activate X-Tools on English Wikipedia you can simply go to gadgets it's under preferences and you scroll down until you find X-Tools you check it and then you click save if you don't use English Wikipedia that much and you want to have it activated on all projects of Wikimedia you can simply go to media wiki the website and go to the page that's titled X-Tools and you scroll down until you find a small piece of code here you copy it and you paste it into this page right here so when you open this page you have your user name and you click on edit source you paste the small piece of code here and you click save and there you go you have X-Tools and pretty much all the Wikimedia projects you can have fun with it ok so last but not least we are coming to the honorable mentions honorable mentions are a really good way to secretly avoid more tools than the important hand categories so let's have a look here we go one of the winners of this category is Listeria Bot by Magnus Manske this tool is a life saver when it comes to generating lists on Wikipedia based on wiki data queries this handy bot is used by brilliant projects like women in reds wiki allows monuments and many more as this user says it is extremely useful for wikipedia projects the other tool that deserves honorable mention this year is heroics copy vio detector by Ben Kertovey no one likes dealing with copyright violations this amazing tool helps detect possible violations for you we've heard this tool is heavily used by our viewers in german wikipedia the third winner of this category is wiki data like sim forms by Lukas Wegmeister in the words of a user of this tool very convenient way to add wiki data as easy as playing Tetris even more it has multiple language support the next winner in the honorable mention category is Convenient Discussions by J.W.V.T.H which allows the user to post and edit comments without switching to a separate page the users of this tool said that they didn't know how they could live without it convenient discussions you are loved have you ever had to use a proprietary poll software? not anymore thanks to our next winner of honorable mention it is a deployment of a free software to schedule events and create polls called from a date on wikimedia cloud toolforge the last winner but not least is entity explosion by Tobi Hudson this tool is a browser extension to discover links and information about the topic of the web page using data from wikidata as one of you wrote taking the power of wikidata with me wherever I go across the web great job entity explosion so that's the end of this award ceremony thanks a lot for joining thanks to everyone who contributed to the tools and thanks to everyone who nominated tools see you next year bye no 9 sat編 no 30 Ulaanál Yotj thank you thanks for the tools for making promos thanks thanks to all theusion oh I hope this video will help you. Thank you for all the tools. I'll give you 15 instruments. Thank you very much for all the tools. Thank you for all the tools. I'll give you 15 instruments.


EU Explorer is a new interactive tool from the IIA created as part of our future of the EU 27 project. This interactive map was developed to build an understanding of the wide variety of views, interests and positions across EU member states. You can use this map to explore each member states vision for the future of Europe and areas of potential policy alignment with Ireland. Explore country by country or by selecting a theme to compare positions across EU member states. EU Explorer, mapping future of Europe.


All right, well, I'm absolutely delighted to be here. In fact, I wore one of my DNA ties to celebrate. I've been told it's kind of humorous on one DNA tie. I'm kind of pathetic to own as many as I do. But I really am so excited about this exhibit, in part because science dominates almost every facet of our life. And genomics is becoming incredibly important to the lives of individuals. We saw recently the kinds of decisions that Angelina Jolie had to make. The food that you eat has so much to do with genomic manipulation and the questions that swirl around that. So it's incredibly important to have an educated populace. And as somebody who does a lot of teaching, I'm acutely aware of the fact that teaching is actually a minority of it is simply imparting facts and imparting knowledge. The most important thing in teaching is to communicate excitement and to inspire students. And I think that this exhibit will do that. I think that it has a leg up on trying to excite people about certain other topics because it not only is powerful, it's not only about you and we're all rather narcissistic. I think that's one reason we like genomic sciences. But because it's beautiful, as really evidenced by the actual structure of DNA, it is an intensely beautiful subject. The human genome is not only beautiful, it's also really big. And everybody has their favorite kind of way of communicating this. But what I would point out to you is that this is about 1 1,000th of the human genome. And if I were to show a slide like this every second, we would still be here 12 days from now and we would have only gotten through the half of your genome that your mom or your dad gave us. So it is a really, really big place. Now, we've learned some things about it. We've learned that it's interspersed with gene fragments and we've got a decent handle on what those genes do. We don't have a very good handle on much of the remaining DNA. And within that DNA are polymorphisms. That is, you have an A where the person sitting next to you has a T. You have a G, 1,000 base pairs later, where somebody sitting next to you has an A. And many of those are meaningless. Some of those influence traits, like what color eyes you have. Some of those influence medically important characteristics and occasionally, people carry very serious changes in their DNA that have dramatic impact on their health. So I think that the long-term legacy of the human genome project, of our burgeoning understanding of life through a genomic lens, will be simply a better fundamental understanding of humans and a better understanding of disease. And that will pay off, okay? It will pay off in the long run and the course of science is stuttering and there's a lot of U-turns. But it is the best way we have found to actually have a dramatic and beneficial impact on patients and on health. But as a physician, I'm impatient and my patients do understand cognitively that yes, research is important for the long-term and they're incredibly generous with their time and they will express to you that I know this may not help me, but I hope it will help somebody in the future. But of course, one can hardly blame them for also wanting some results now and we all want that. So what I wanna do in the next few slides is just explore with you where the near and mid-term reality of genomics is and how it is beginning to help patients now and where we may expect real solid advances in a good timeframe and a favorable timeframe. So new technologies are oftentimes derided with the old adage that when you have a hammer, everything looks like a nail. And God knows, you know, we've been wailing away at every organism we can find with the hammer of genomics. But it's also true that a hammer is a fantastic tool if you hit the right nails. And the question then is in 2013, what are the right nails in sick people and in healthy people to really make a difference in their lives? Well, I think that the nearest term benefit of genomics in medicine will be as an unprecedented diagnostic tool. And we are already seeing this in the genome. And let me give you an example. We're fortunate enough to have one of the CSER grants, the clinical sequencing exploratory research grants. And this is a case of an individual, 47 years old, a female with sudden cardiac arrest. She was resuscitated successfully, thankfully. But on EKG, it looked like she might have a syndrome called long Q2 syndrome. It's actually kind of hard sometimes to judge that by an EKG. It's not a great way to diagnose it. But these individuals are at very high risk for sudden death, which you can well imagine is not a fun thing to be at very high risk for. It is a treatable condition if you know that somebody has it. But it's hard to know that until after they've suffered sudden death. And knowledge of which gene is mutated affects your choice of treatments, all right? So it really has some medical management implications. The problem is that dozens of genes have been implicated in this entity. So until we had massively parallel sequencing at our disposal in a clinical context, we were really unable to define the particular mutation that would be responsible for an individual's long QT. We now are routinely in this project applying this technology to individuals with this syndrome by sequencing a whole panel of genes. We can therefore define the mutation in many of these individuals and not only guide their treatment, but we can also illuminate who else in their family is at considerable risk and needs to see a cardiologist get on medication, perhaps have an implantable defibrillator, et cetera. NHGRI is funding multiple types of investigations into how to apply this. So the thing that I wanna emphasize about genomics is it's like in many ways any other highly complex and wonderful technology in medicine. Think about the MRI for a minute. MRIs are miraculous technology but we don't just go willy-nilly getting MRIs on everybody who walks into our office. That would not only be wasteful, it would be begging for false positives that would do people harm. We need to understand how to use genomics in a targeted and rational way where it will really benefit people. And I think that for the time being it's a subset of patients, very important subset, but nevertheless a subset of patients who stand to benefit in the near term. For example, those patients who have disorders that are caused by mutations in many genes, like the entity I just told you about, LongQT, there are many such disorders. Those with enigmatic conditions but who have clues to suggest a primary genetic etiology, for example, a family history. Progressive neurological disorders seem to be disproportionately caused by underlying genomic issues. And children with multiple malformations. This is a particular interest to me in the sense that many diseases have many different components, but when you think about it, you turned into a human for one reason and one reason only, and that is that you have a human genome. Had you had a bat genome, no matter how you were raised, you would have turned into a bat, okay? So when we see children with birth defects, all right, there's a high probability, many of us suspect, that we will see defects in the genome that have given rise to those. And this is another group in which we're applying whole exome sequencing and beginning to elucidate these problems. It is really thrilling to be able to go to patients as I did twice in the last week and tell them that because of their participation, we actually have elucidated the condition that has caused this problem that you have suffered with for, for example, in one case, 30 years, a woman last week with a neurological problem. And in that particular instance, it led to a recognition of what would be dramatically effective treatment, so it's a real thrill. Eventually, these things will inform our approach to common diseases, but that will come after we've picked off the easier targets of things that are predominantly or almost wholly genomic. I will just spend one quick slide on this because it's been alluded to. The genomic analysis of cancer is an area where even in my somewhat, you know, I try to have a fairly sober view of applications will, perhaps, and I don't use this word lightly, revolutionize the treatment of cancer in the midterm. For over a century, we have defined cancer by its appearance under the microscope and its presumed tissue of origin. We are now, because of genomics, able to dissect tumors in a functional way and really define the specific mutations that are driving the growth of that tumor. That leads to an ability to guide treatment by identifying the Achilles heel of each tumor. And I think that eventually, it's not gonna go away the need to know where a tumor came from. Its appearance under the microscope, I suspect will matter, and there's some interesting new evidence to support that. But I think our categorization of tumors will rely at least as much upon the genomic profile of an individual tumor as on its source. Again, the NHGRI is funding some very important studies to try to exploit this underlying genetic aspect of cancer. So this is the world's happiest colonoscopy patient, Katie Couric. She has a real interest in promoting colon cancer screening because her husband, Jay Monahan, died of colorectal cancer in his 40s. And he almost certainly had Lynch syndrome, a syndrome that causes an extraordinarily high risk of colon cancer, but is very preventable if you know about that risk. And the thing, though, that we have to be careful about as we apply any medical technology to healthy people is it's much trickier than even applying it to people who already have disease. In some ways, people who are healthy have more to lose, right? In some ways, we can only hurt you when we start inflicting medical care upon you. There's also a different relationship between the provider and the recipient, right? Patients come to us for help. They oftentimes recognize the limitations. In a public health setting, we're going to people who aren't patients and saying, hey, we've got a deal for you and we want to do something. That's a very different relationship. The benefits are less obvious. In the public health setting, what you get to say is, hey, I've got good news for you. You didn't get sick, right? And that's a little hard to internalize because not getting sick isn't quite as evident as getting cured of a disease. And the downsides are easy to see. And the point is that every intervention has a downside. I tell the students that there is only one kind of drug that doesn't have side effects, and that's a new drug. Because no matter what, the more experience we get with something, we know that we will see downsides. So we have to be very careful as we start to approach healthy people with our genomic tools. That said, I think there are tremendous opportunities. I think that we will benefit from the preemptive delineation of certain pharmacogenomic variants, variants that influence how you will react to certain drugs. I think we will see it as an adjunct to newborn screening. And indeed, NHGRI is about ready to announce a series of grants that will explore the use of genomics in the newborn screening setting. Pre-conceptual carrier screening is a very exciting arena because the ability to look at many genes is an ability to inform parents as to their risks of having children with very severe diseases. And right now, we are very constrained in the kind of pre-conceptual carrier screening we can do because we've only traditionally been able to look at a handful of genes. And we're going to be able to expand that dramatically. One idea I'm particularly excited about because I think it could be a near to midterm benefit of applying genomics to the healthy if we study it appropriately and the evidence bears this supposition out is what I like to think of as newborn screening for adults. There's me as an infant with one of my DNA ties. The point is that about 1% of people walking around out on the street harbor a mutation that leads to a very high risk of a preventable serious disease. Think for a minute about Lynch syndrome. This is a syndrome that I alluded to a minute ago.  But if they know about that risk, screening modalities with colonoscopy can reduce that risk of ever being diagnosed with cancer by at least 10-fold. So it's highly preventable if it's known. The problem is that currently this is how we detect people with Lynch syndrome. We wait for several people in their family to get cancer and or die of it. Well, the horse is kinda out of the barn at that point and it's very appealing to think that perhaps we could use our new genomic technology to screen part of your genome at the right time in your life to detect those individuals who carry these serious mutations. If you add up other conditions like Lynch syndrome, what you get is that somewhere around 1% of people have mutations that are conferring upon them a very high risk of a serious but preventable disease and we could benefit millions in the US if we pursue this and if indeed these suppositions turn out correct. And we actually are very excited because we've just gotten a grant from NIH to start on a very small scale to investigate whether this might work and what some of the ethical, legal and social implications of going to healthy people and doing this kind of thing are. There are a lot of challenges as we go forward. I'll name just a few of them. One is accuracy. Most of our next generation sequencing platforms have about 99.99% accuracy. That's really good until you remember how big the genome is. Cause when you multiply that by three billion, it means that you have about 300,000 errors per patient every time you do a whole genome sequence. That's not trivial, right? Interpreting the variants we find, I feel is the single biggest challenge going forward in genomics. We, I cannot tell you how often, every week at our molecular sign out conference, we see a variant. This person has disease X. There's a variant in gene Y that has been associated with this disease, but we don't quite understand how to figure out in many of the cases whether that variant is just a chance event in this person or whether it's causative of disease. And these are tough, tough problems, but I think that that is one of the biggest challenges and one we're beginning to make progress on, but it remains very big. Storage and access in the medical record, I've been treating patients long enough to remember when charts were paper charts and you couldn't read the writing and you'd get a patient and the charts would be this high. Things are a little better now, but could get very ugly when you think about the fact that we all have four million variants. Are we really gonna put those into your medical record? Do we need to put all those into your medical record? How do we retrieve them? We've got to figure those things out. Obviously, education of patients, providers and public is important. Again, I'd emphasize how important this kind of exhibit is in the general public feeling more comfortable with this field and understanding it and hopefully seeing how exciting it is. We have to craft policy regarding the use of genomics and you can't go very far with genetics and genomics without talking about reproduction because that's what it's all about in the end. And this gets to be very, very delicate when one starts to craft policy around those areas. I would also just mention as has been alluded to that you are actually not mostly human, right? Only one out of 10 of your cells in your body is human. Now, most of your weight is human because human cells are a lot bigger, but if you just look at the number of genomes we have, viral, fungal, bacterial genomes outnumber your human genomes by about 10 to one. I think this is a huge area of excitement and with potential for medical application. We aren't there yet. We don't have microbiome clinically ready tests to do, but I think that's coming. And NA and HDRI again has been at the forefront of funding some of these things. I wanna end with just a caution and that caution is that when you analyze a person's genome, you inevitably obtain what we call incidental information, all right? Your genome is not necessarily a warm and fuzzy place. When we do sequencing, say whole genome sequencing on you, we're gonna find things we simply weren't looking for, all right? I think actually LMO needs whole genome sequencing. You notice he only has four digits on each hand. But some of these will be trivial, some will be beneficial, right? I wanna know, it wouldn't make it a good day to be told that I have a Lynch syndrome mutation, but actually I think I wanna know that if there's something preventable that I can do. Some, however, are highly problematic. We're gonna occasionally discover dramatic risks of lethal, untreatable, unpreventable disease. And some people wanna know that or think they wanna know it and some don't. So let me just ask you two questions, all right? I'm gonna show of hands. Think about a few serious but highly preventable diseases that sometimes are highly genetic. I talked about Lynch syndrome. There are four, well, at the Angelina Jolie story with BRCA mutations, certain types of thyroid cancer, aortic aneurysm. If you personally carry a mutation that essentially guarantees you will develop a serious but highly preventable disease, who here in the audience would wanna know that? I would wanna know. Is there anybody who wouldn't wanna know that? Who's willing to raise their hand? Okay, I think that's certainly typical of my experience. But let's turn that around and think about a few really ugly diseases, okay? There are forms of Alzheimer's disease that are essentially totally genetic. You will get Alzheimer's disease if you have inherited one of these rare mutations. One of the more grim, named diseases I'm aware of, fatal, familial, insomnia, everything that sounds like it is. These are diseases that have no prevention, no treatment, and if you carry a mutation for it, you're gonna get it, essentially, 100%. So let me ask you personally, if you carry a mutation that essentially guarantees you'll develop such a severe, unpreventable, untreatable neurological disease, do you wanna know? So who would say yes? Who would say no? Who would say I'm not sure? I think you guys are the ones that are right and I say that because we do have some empiric data and we have these data on people with Huntington's disease in their families and it turns out that individuals, even though many of them say, yeah, I'm gonna be tested, in the end, if you look at who votes with their feet and who gets testing for Huntington's when mom or dad had it, so they really understand the disease, fewer than 20% decide to take the test. I think what that says is denial is a great mechanism we all use every day to get through our lives, but the point is we're going to have to grapple with these kinds of questions as we go forward with an increased understanding of the genome. I'll end with just a few other social challenges for which I don't have any solutions, but we're going to have to grapple with them. Genetic discrimination is a reality, okay? Not in the sense of healthcare because with the genetic information non-discrimination act with healthcare reform, it's really not an issue. And I can tell patients, thankfully, finally, that no, you don't need to worry about losing your health insurance if you get this genetic test. But there are other kinds of insurance that are very important to people. Long-term care insurance, disability insurance, life insurance, there are no laws, all right, there are no regulations that limit discrimination based on your genomic profile for those. If I were the nefarious CEO of a life insurance company, I would be thinking about whether it made sense to start doing DNA sequencing for certain genes on people who applied. And I think we're going to need to figure out how to deal with that. The threat of allealism, okay? I thought that was a little conjectural and hypothetical until I saw this quote in the Washington Post, we envision a new type of community where people will come together around specific genotypes. There is a dark side to that, right? And I'll let you think about that. Gene potting, right? As of today, the Supreme Court has made a ruling that my, you know, I was really delighted to hear what Karen Rothenberg and Larry Brody had to say about it because my initial take is that this will open things up for people who need genetic tests and I think that'll be good. There are real privacy issues. Genomic information is digital, right? That's not a metaphor, it is truly digital. And we live in a digital age where that kind of information is easy to disseminate and increasingly easy to hack. And we're gonna have to figure out how to deal with that. I like Scott McNeely's comment that privacy is dead, deal with it. I think privacy is dead. I mean, if anybody's been following the news lately, we have to figure out how to deal with that, right? And it extends into genomics. One of the major direct-to-consumer companies offering genomics went bankrupt a couple of years ago and one of the envisioned solutions for restructuring was that the data that that company had collected would become the property of a venture capital firm in Cambridge, Massachusetts. That is not probably what the people who spit into a tube and sent it off to that company had envisioned for their data. We're gonna require an educated public and educated policymakers to successfully grapple with how we handle these challenges. And that is probably the biggest reason that I'm delighted that this exhibit is opening and was really, really flattered to be able to play a very small role in it. The Smithsonian's been an inspiration to generations of scientists and I certainly count myself among that group. So thank you and if you have, I don't know if we have time for any questions. I think if we have a burning question for Jim, Dr. Evans, we'd probably want to entertain it. Great. Okay, then I would like to introduce Dr. Lara Rodriguez from the Genome Institute. She runs her division of policy, communication and education and she can wire herself or if you just don't walk around, you can stand at the podium. And Dr. Rodriguez will talk about what do we do with all this data?


Ευχαριστώ για όλοι και ευχαριστώ για έναν άλλο βίντεο. Σήμερα θα σας διεθνώ την τελευταία εργασία από τα τελευταία εργασία μου. Εδώ είναι η κομμάτι και έχω inside everything that has been released. Αυτό δεν είναι ένα σπόνσορδο βίντεο, δεν πέντω να κάνω αυτή, αλλά έχω σημαίνει τις εργασίες κάθε μήν. Λοιπόν, νομίζω ότι είναι ένα καλύτερο εργασίες για εσείς να παίρνουμε ένα καλύτερο εργασίο σε όλες τις εργασίες και ελπίζω ότι η βίντεο θα πρέπει να σας βγει, πως να φυσικάσουμε ποτέ για εσείς. Λοιπόν, πρώτα να ξεκινήσουμε αυτό. Αυτό αυτό είναι το Λευταία Βιπ. Μεταφέρουν 3 τελευταία. Αυτό που σας διεθνώ ένα με άλλο με ένα γρασί. Και αυτή η λευταία εδώ θα σας βοηθεί να βρεις τελευταία εργασία. Θα σας δείξω ένα παράδειγμα σε αυτό το βίντεο και θα δείτε πώς αυτά τα τελευταία βρήκουν. Και σε αυτή η λευταία έχω έναν άλλο εργασίο. Αυτή η λευταία είναι called Slider Surprise και θα σας βοηθεί να βρεις λίγο λευταία εργασία που μπορείς να βοηθείτε underneath λευταία εργασία or even a gift card. Και θα χρησιμοποιήσω αυτό σε αυτό το βίντεο. Λοιπόν θα μπορείς να δείξεις πώς αυτό λευταία εργασία. Αυτό είναι το Λευταία Βιπ. Μπορείς να βρεις όλες τα τελευταία για να βρεις ένα λευταίο τελευταία. Βρεις ένα λευταίο παρακολουθείο για να βρεις όλες τα τελευταία, ένα λευταίο παρακολουθείο με τα τελευταία σας ή έναν τελευταία. Έχουν μια σχέση όλων των αυτών οπότε πρέπει να το δείξεις στον εξαιρετικό website. Αυτό είναι το Λευταία Βιπ. Έτσι δίνει λευταία, μάτια, γεγόνες, κορσίες, νσί, λευταία και ένα μεγάλο σκέψι. Μπορείς να χρησιμοποιήσεις αυτές κορσίες. Αν έχεις όλες τα τελευταία στον εξαιρετικό website πρέπει να το δείξεις αλλά θα σας δείξω λευταία με τα τελευταία που έχουν δημιουργήσει αυτό το μήν. Ας δούμε την τελευταία. Αυτό είναι ένα μικρό τελευταία που είναι called Well Hello. Έχει αυτό το μικρό τελευταίο και τα μικρά τελευταία που μπορείς να κατασχέσεις. Αυτό είναι ένα από τα τελευταία που εσείς να χρησιμοποιήσεις μετά και μετά και να χρησιμοποιήσεις μετά με αυτές τα τελευταία που δημιουργήσεις μετά και μετά για να μπορείς να κατασχέσεις δύο. Αν σας αγαπείτε μεγάλο σημερινό να κάνετε έναν σημερινό στον εξαιρετικό αυτό είναι για εσείς ειδικά. Θα αγαπείτε μεγάλο σημερινό με τα τελευταία στο μικρό τελευταία να αγαπείτε μεγάλο σημερινό και μετά. Αυτό είναι called Cute Cloud Outlines και δεν χρησιμοποιείται μόνο το κλαού but it also cut out a little border that you can use separately or together. Αν σας αγαπείτε μεγάλο σημερινό με τα τελευταία στον εξαιρετικό then having a die set with clouds is a must have since it gives that extra detail on your sky. Εδώ είναι ένα μεγάλο σημερινό Thank you in a lovely phone script perfect for all those cars where we want the focal point to be the actual sentiment. Our favorite girl is back this month and the stamp set is called Hey Sunshine See is on vacation and I absolutely love this stamp set I will be using this on one of the cars that I will be sharing today. There are also merchandise available that don't come together with the stamp set you have to get them separately I just like to store everything together. If you like creating cute cars for your little friends then this is the set perfect for you it's called Very Good Friends it comes with three little fairies in different positions and lovely sentiments perfect for birthdays as well as friendship cards and there are merchandise available if you want to pop up your images. This is the fish you were here stamp set it comes with lots and lots of fairies as well as sentiments and merchandise available there are little bubbles and you can also combine it with this die set that I showed you earlier to create a lovely underwater scene and I do have another ocean related stamp set in this release which I'm going to show you in a bit but first let's take a look at those flowers this is called Tropical Flowers you get flowers as well as leaves and there are merchandise available it's one of the layering stamp sets where you can stamp one on top of the other to create different effects but of course you can use them separately it is really forgiving I will be using it on one of my cars today but we will see that you don't even need to align these stamps one on top of the other they are really forgiving this is the Friends with Fins stamp set again an ocean themed one and there are merchandise available there are lovely creatures here you will find a narwhal a dolphin a shark a whale and I'm going to show you the other one so you can compare the two together they both give you secretures and sentiments to work with so you can easily create underwater scenes with any of those but the last one has larger images so depending on what you like to do you can choose your favorite and last but not least this is the Picnic Pulse stamp set and there are merchandise available it's one of the Stacey Yakula designs which I absolutely adore and MFD releases one stamp set every month so this month you get three creatures a tree as well as a picnic basket and a watermelon if you love creating little scenes and coloring in stamped images then I'm sure you will absolutely love this one now I'm going to create three cards using many of the products from this new release and you can see them in action I'm starting out by applying some distressed oxide ink on my non-stick craft mat I'm spraying some water and then on top I'm going to apply some watercolor paper the colors I used here are tumbled grass and peacock feeders so I have created a first layer I'm going to make sure that this is completely dry and then I will go ahead and dab this on top of all those splashes just for a more interesting look I'm going to leave this aside to dry and then I'm going to cut it out to be slightly smaller than the standard card but instead of stamping I will stamp my little girl with permanent ink so it's not going to smudge or smear since I'm planning to color it in with my alcohol markers I'm not going to share the coloring since this is not the point of this video and it's going to turn super long so all I did was to use the matching dies to cut it out and I'm putting my card together the sentiment also comes from the same stamp set but the color troubles float away which I'm going to stick on top of my card again with foam tape at the back to embellish my card a little bit more I'm going to add some dots of glue this is my Novo Deluxe glue here and I'm going to stick on top some transparent bubbles I then place this panel on top of a standard card that's 4.25x5.5 and here is my finished card moving on to the second card for today I will be using the slider surprise dynamics so I'm separating the dies here and I'm going to cut out 2 pieces using the 2 dies I cut out everything of white cardstock and once you cut it out you will see that there are 2 score lines in this bigger piece which I'm going to score with my bone folder and make sure that I have a nice crease I have slowed down the speed of the video so you can see exactly what I'm doing I have turned this at the back and at the bottom flap I have added some double sided tape and I'm going to align that second piece with the flap at the bottom so these 2 pieces are only connected at the very bottom and once I turn it on the other side you will be able to see pretty much how this mechanism is going to work I'm going to show you how the mechanism comes together later on so first I'm going to do some stamping and then I'm going to stamp the wings all the stamps here come from the Tropical Flowers stamp set and I'm starting out by stamping the leaves I'm using my MFT ink cubes in various colors and for the leaves I'm mixing up a darker and a lighter shade of green some of the images when they are quite big I do use my misti to stamp them for smaller ones I don't even bother and I go with a small stamping block now all the stamps have a marking so you know which one goes with which one for the layering and also they have a little arrow at the top so you know how to align them but I didn't even bother to align them I just placed the center on the flower and stabbed it it doesn't really matter how you are going to place these flowers together and you can play and create even your own combinations and here they are all ready to go, leaves and flowers I'm going to use the matching dies to cut them out and now I'm going to show you how to put the sliding mechanism together so here are my two cutouts and remember that they are connected only at the very bottom flap now at the back I'm adding some thin foam tape all around the frame making sure that I don't go over the slider so this foam tape is really important because it's going to create kind of a box for that slider to move up and down getting out of place so I'm going to turn it around after I peel off the backing of course and stick it directly on top of my card base and I'm going to show you how this works it's really easy to do, they are just two pieces connected together at the very bottom flap now underneath that slider you can even hide a little gift card you can even stamp your sentiment which is something that I'm going to do today and of course you can decorate the front as I stick my cutouts there to create a flower composition I always keep in mind that this is a moving part and I don't want to block it in any way for the flowers I went with foam tape at the back and now for the leaves I'm going with white glue now if you visit the youtube channel by MFT you will find that video by Stefani it's a really step-by-step instruction video on how to put this slider card together and a completely different idea on how to decorate it now at the top you can stamp the word pull or like I'm doing here just to make it easier for the recipient to open it up I made the mark with a pencil on where I want my hole to be now I'm using my cropped die to create the hole and I'm going to thread some ribbon I'm going to use some white thread to tie a little bow something for the recipient to hold on to while moving the slider up and down I'm going to stamp a little sentiment hidden underneath that flap that says from me to you I'm stamping that with black ink and it comes from the well hello stamp set so when you open it up you can see the little message revealed you can leave the card as it is but since I had this beautiful hello die I just had to use that as well and I'm going to combine a light yellow which is the same cardstock as my card base and I have also cut out the word hello out of white cardstock I'm going to stick those pieces together I'm going to add some glue at the back of a hello piece and stick it at the very bottom of my card making sure that it doesn't block the slider I love interactive cards and I hope this is going to put a smile on the recipient I'm going to finish it off by adding one of my Instagram followers I will make a post there later on today where I'll give all the instructions here are some close up photos on this interactive card and now I will move on and create another interactive card with this unique die set in this set you get 3 dies one is a border of waves the other one is a border of waves the other one is a border of grass and you also get a little piece that is actually the pop-up mechanism for this card today I will be using the waves I will use 2 pieces of cardstock the larger one is 5 ¾ by 5½ and I have a smaller one the width is 5 ¾ and it doesn't matter how high it is since I'm going to use the border die to cut out waves out of this and now it is really important to have your width at 5 ¾ if you want to end up into a standard card size we are going to do some scoring but I'm going to show you everything step by step so here I'm working on the smaller piece and with my blending tool I'm applying some Distress Oxide ink I'm going to combine 2 colors of Distress Oxides this is Salty Ocean and I'm going to add a darker shade which is Faded Jeans I applied some Water Splashes I'm letting them for a few seconds to react with the ink and then I'm going to blot them with a clean paper towel now here are my 2 pieces and I'm going to do some score lines now on the blue one I'm going to do 2 score lines on the left side so here and on the white one I'm going to do 2 score lines on the right side I'm going to place first the blue paper on top of my scoring board and score lines on this side and I have to score at 3.25 and at 1.5 and of course I'm doing the scoring at the back since that was the only way I could neatly align it on my scoring board and now on the white piece I need to score again at 3.25 and at 1.5 now I'm going to place them next to each other I have the folds and I'm going to use my bone folder and make sure that I fold this really nicely you need to create 2 z folds on both those pieces and once you fold it you will see that this now is a standard card size so that's 4.25x5.5 and I'm going to do the exact same thing on the blue piece once you fold this part it's going to be 4.25 and here is kind of a preview of how you are going to put those things together so you know where I'm going for now there are 2 score lines on the popup mechanism which I'm going to reinforce with my bone folder and if you want step by step instructions on how to put these popup cards together you can also go to the MFT youtube channel they have great instructions on how to put these cards together how to use the dies and that's the instructions that I follow for creating my own card as well as the focal point for my card I'm going with a whale and this comes from the friends with fins stamp set I'm going to stamp it with permanent ink and color it with my alcohol markers and I will use the matching dies to cut it out now this is going to be my focal point and at the same time the little image that is going to pop up with my mechanism I have a very thin strip of white cardstock that I have cut out this can be an acetate and I'm going to connect those 2 pieces together with some double sided tape and that's my mechanism this is where I'm going to stick the whale on the other end but I'm going to make sure that this is not going to show at any point at the front of my card now I'm going to stick the other end with my mechanism at the fold of the wave so you can see how this is going to align at the fold and once you put that in place you can kind of see how this is going to work so now I'm going to turn it around and check where this sticks out I need to make sure that this doesn't show at all so I'm going to cover up as much as I need to with my whale stick the whale there and just chop off the excess I don't know if it looks complicated but it really isn't once you make one of them you will see that they come together really easy and also make sure to see the good instructions at the MFT website now all I have to do is to put together the waves with a white card base for that I'm using some double sided tape on the flaps I'm going to peel off the backing and stick those 2 pieces together they should align perfectly now here I have everything folded and trying to align it but here is a good tip if you lay both those pieces completely flat like I'm going to end up doing here you will find that it's super easy to do and this card is really fun I can keep on playing with it so anyway I'm going to add some finishing touches to it so I have some splashes that come out of the top of the head of my whale for that I'm going to make sure that I know exactly where she's going to go and then stick those splashes at the top and just next to those splashes I'm going to stamp my sentiment the sentiment comes from the same stamp set as the whale I'm going to do some double stamping so first I'm using salty ocean and then I'm going to switch to faded jeans which I'm going to apply only at the very base of the lighter so I'm touching only the bottom edge I'm going to stamp that and I will end up having a nombre look on my sentiment and of course the colors that I used for the sentiment are the same that I used for the ocean now all I have to do is to stick this panel on top of a standard card that's 4.25x5.5 and it's going to fit nicely inside an envelope and although when you open up this card it looks quite dimensional just like a shadow books or one of those diorama cards you see that inside the envelope it looks completely flat once you get the hang of it and since you have the grass as well you can create so many different scenes with many different cutouts popping from the pack it looks very simple but it's really fun to play with so here are all the 3 cards that I made for today you will find all the links down below in the description area as well as on my blog I hope that you had fun that you got inspired and if you did don't forget to leave me a comment to like and subscribe if you haven't done so already thank you all so much for watching and I'll see you all next time


What's up everyone it's your girl Kenzie here from Layton Sports Cards, and I'm ripping a couple personal boxes for Jeffrey H We've got three of the new release 2022 penini prism footballs. All right Jeffrey here. We go good luck Hold a manga yesterday Justin Jefferson I like the what are they called profiles this year I haven't pulled one of those and have a thing glass or a color blast and that's those are hard I've only pulled like one or two color blasts ever very hard pulls Exactly Greg absolutely explains it Too much going on on my head. We've got a hype of Javante Williams hyper to 175 Tyler Algier Falcons Garrett Wilson rookie and Evan Neil Childbirth that is very true. Let me tell you pregnancy brain continues after you have the baby It really does Silver rookie of Charles Cross who got a purple power up next to 49 is gonna be a Mike Evans for the butts 35 of 49 Pierre Strong Jr. and Roger McCrary got all out silver of Joe I have to do like short ones or else how he's gonna make fun of me again Chris Johnson on the green scope to 75 Trayvon Walker rookie and Drake Jackson rookie nice Cooper. That's cool Yeah, zappy stuff is might be a hole. You know, you know, never never know Merchant Skymore blue wave DJ more sick color match here Carolina the 199 Brian Cook and Khalil Shakir Again y'all we got basketball and baseball release this week gold label and Origins basketball gold label baseball origins basketball. We have purple ice of Leroy Kelly Browns to 225 Traylon Burks and Prison break silver of Jamar Chase Orange Tom Brady, you know Bucks 215 of 249 some nice bucks cards coming your way Jeffrey Trey McBride and Evner Fireworks rookie of Johan Dotson Purple Garrett Wilson nice one there for you Jeffrey. That one is 122 of 125 Purple Wilson Kenny Pickett and Chris a lot of a rookie. It's up a lawn. Oh man six kids. Yeah Hopefully it doesn't get worse as as More kids come along. I got silver Josh Jacobs Red wave of Rashawn Gary to 149 Charles Cross and Hassan Haskins. All right, come on silver chase young. All right. We got our first auto Here we go. It's like a Patreon Mathis for the commanders on the rookie auto Patreon Mathis they kind of went back to like 2017 2017 Prism where all the autos are silver kind of like all the rookies were silver country and Aidan Hutchinson Which is nice Yeah, definitely gives me a select feel a brilliant Jonathan Taylor Blue ice Danny Dimes to 99 40 million dollar contract Skyler Thompson Johan Dotson I know a lot of Giants fans that were not happy about that Silver and Kwan Bolden and your last I don't pull from the back. You're a latte Taylor We've got a Derek Stingley Jr. It does look like the foil is lifted on the back right there. I can tell already We'll send a box here with you Jeffrey Show us a big hit. Come on They can't ooh to 149 I'm Ole Miss. It's gonna be a Mac Corral on the red rookie wave auto Here you go, Jeffrey. Nice Corral To 149 again, it was a bit lifted right there in the bottom middle So we will send a box with you on that one Silver rookie fireworks Kenneth Walker the third hyper to 175 Ken Anderson I'm Malcolm Rodriguez and a Drake London box to And y'all thanks for tuning in to the Sunday daytime personal stream you're ripping till about three o'clock So about three fours will be live at five for group breaks Some Sunday fun day stuff going on AJ Dylan silver blue ice of Jamal Adams for the Seahawks to 99 Jameson Williams rookie and David Bell You have any questions? Let me know tons of stuff up on the site including some new releases from this week As well as some older product that a rich order for Some fun Eli Mitchell silver. We have Washington auto again this time a Curtis Samuel for the commanders Curtis Samuel Frisker and woolen of Mike of Parsons Purple Brandon I for the Niners to 125 Carson strong rookie and Jake Ferguson. Yeah, that's a big upset to Arkansas beats Kansas. Yeah by one point man Silver rookie for the rave or I'm sorry orange rookie for the Ravens Isaiah likely to 249 So we're white and loose sign Black silver hype of Devonte Smith I brought a 175 mile Sanders Romeo Dobbs and Troy Anderson brilliant Jalen waddle Purple ice of Roger Stalback for the Cowboys to 225 Isaac Pacheco Pacheco and Dylan Devon Lloyd No Cooper. Yeah, just the empty box and wrapper so he can take it up with panini They usually ask for a wrapper and whatnot. Sometimes silver rookie Alec Pierce Purple ice of West West Walker to 225 Skyler Thompson and Johan Dotson rookie silver all out of Cordell Patterson Blue Wave Troy Anderson Falcons to 199 Derek Stingley Jr. and Elanti Taylor Emergent rookie Aidan Hutchinson orange DJ Moore to 249 Malcolm Rodriguez and Drake London Silver of Devon Singletary next auto up. We've got to 149 a Garrett Wilson on the red wave auto. There you go, Jeff nice hit 75 of 149 we'll make this one for you Jeffrey Very nice hits Juanmu and Isaiah Spiller back to back boxes the nice red wave auto got silver rookie emergent of George Pickens Purple powered a 49 Michael Gallup Cowboys Logan Hall and a Calvin Austin the third Last box to here We've got blue ice hype Devonte Smith to 99 Love the look of these cards Purple ice of Fadrian Mathis for the commanders to 225 Jack Jones and a Barack Purdy Joshua, how's it going? Do you watch the rest of those Bowman best breaks yesterday? All right, last box here for you Jeffrey. Oh, wow Got brilliance Jamar Chase red wave rookie of Jordan Davis Eagles to 149 Tyler Algear and Desmond Ritter rookie There you go. Yeah, Joshua. You had a great last break What's up Josh, how's it going? That's silver rookie Chris Olavi Purple ice of Ronnie lot to 225 Greg Doolitch and Ekbeke Got silver lockdown Micah Parsons orange Terry McElorn commanders to 249 Sauce and Nick Benito Fireworks Russell Wilson a red wave David Carr 149 Kobe Dean and Kyle Phillips Yeah, yeah, Dylan's here. Yeah, I don't know if you're a fan of Gold label, but that comes out Wednesday You've got prism or a hyper of shackle entered for the Colts to 135 Wanda Robinson and Trent McDuffie Like the gold frame Fireworks silver Patrick Mahomes Hey, Gary. How's it going blue wave J Jeff? 199 George Pickens and my face Merchant rookie Malik Willis we have a purple power Rookie Tyler Algear nice one there Falcons 5 of 49 Yo Jeffrey nice purple power there Booth Junior and Snoop Conner. Yeah, that sounds about right Silver Davis Mills. We've got orange Max Crosby for the Raiders to 249 Malik Willis and Jeremy Ruckert Silver Fletcher Cox We have to 149 a Sensational signatures auto of Gus Who's this free rot for Roddy for Roddy I've never never heard of him. He's a little Little for my time. I believe What is that every box we pulled a Washington auto out of yeah, that's kind of crazy. Yeah, that's true Redskins throwback there James Cook and Kyle Hamilton rookie for rock Thanks crumb Let's say that first. I said for Rod or for Roddy that he always trips me up at the end You never know when you're supposed to pronounce it or not Kenny pick it prism break orange wave to 60 Brian burns Panthers Mantra Washington and Christian Watson No, the original TV 12 is Terry Bradshaw He looks like he may have played during the Bradshaw Maybe a little after You got silver Kyler Next auto here. Oh my gosh another Washington auto a rookie auto of Jahan Dotson It's a nice one there though Jeffrey three boxes for Washington autos. My goodness Jordan Davis anti-quant-thorton last factor And if this was a group rate whoever would have the commander spot would be loving it We've got silver brilliance of Aaron Rogers purple Zach Wilson Jets to 125 Rashad whites and a Kyler Gordon Alright, that will do it for your boxes there Jeffrey again Show you your autos that you had Johan Dotson the Gus Fura Curtis Samuel Mathis rookie auto Matt Corral to one 49 on the red again We will be sending a card as the bottom down here It was a little lifted then the red wave rookie auto of Garrett Wilson to one 49 Nice hit there Jeffrey. Thanks as always for all your support. Congrats on the hits. We'll get them right out to you


I've been wondering about this since I started my Death Note reactions. What if I want to write an animal's name in my Death Note? Not that I would. I love animals.  So my Death Note would be all humans. But I'm just sayin'. Say a cat comes through my window. I'm on like the sixth floor. I don't know what I meant by that. Say a cat climbs up to my window and bites me and I want it dead. And what if I caught a glimpse of his dog tag? I'm just wondering. Let me know down below in the comments. Anyways, today we're doing the Unraveling, which is one of my favorite anime songs that was from Tokyo Ghoul. So I'm guessing there's a crossover in this episode. If not, I'm gonna be very disappointed. Let's get to it. Nick, don't do that. That's an anime thing. Yeah? Guess what?  Too far, too far. Okay. Let's do this. Unraveling. Oh my god. You're gonna start an episode like that? All you foot-freaks out there. I don't judge anybody's fetish. Do you? If you fetishize toenail clippings, it's not bothering me. So go ahead and swallow those things.   He's a human being!  You know what I mean? I think he knows all your names already. I think he knows your entire backstory.  What? It's like he put that together already. He's not a human. No human looks like this. Is that eye shadow or is he just as slept in a month? They're about to pull out their Walkmans and their flip phones. Cause this was in the 1960s, apparently. Look, they do have flip phones. El? Dude, I'm more like El than Light. I'm renaming my channel, Nikolas El. Before you leave, I gotta use the Men in Black stabilizer thing to erase your memories because Light can get into your head somehow. They're like, The way he's sipping it from a 360 degree angle coordinates how he's gonna attack Light and then Light is gonna retaliate with the use of the Death Note. But then El, by the 360 degree angle in which he drank the coffee, he studied the way the liquid was moving in a 360 degree angle, confusing his brain.   I don't think that's safe. Oh, El's not gonna survive.  Wait till Light hears that. Damn, Mr. Yagami already called him Ryuzaki. This is why Mr. Yagami is gonna live. That's true, man. That's when I knew Light was psychotic. Once he did that, then he went after Rape Hember. Kind of reminds me of the lizard.  You don't need their help.  The whole world is my hostage.  El is just thinking of everything.  He just doesn't want you to die. That's why he's around you. Man, do you hear this music? Whoever did this, you need to hit me up and make like, intro music for me. Don't be so excited. Exactly!   They could be like, Those would be a Pokemon thing where it goes from screen to screen.  He's like, I'm too smart to hold a pen the way everybody else does. I hold a bite the tip. My god. Go to sleep, El! Look at him! His eyes have been open so long, he lost his eyelashes. Why? Why show him? I still feel bad that he's dead. Oh, we gotta deal with his wife now. Who's probably gonna die, too? I think the light needs to starty. Oh my god. Dude said fuck's cool. Look, he's doing quadratic equations right now with integers, integers. See, I don't even know the word.  Who does this? The clinically insane do. They're both crazy.  I'm telling you guys. Imagine their baby. Ellen likes baby.   We couldn't think of that. Man, I don't even gotta watch this show. I could just close my eyes and just bump it, man. I'm about to pull up Death Note episodes at the gym and just be like this. They added the drum track and everything. They know what they're doing, man. They're like, our show's so good, you don't even gotta watch it. Oh god, why are you so excited? Do you know? Excitement leads to death. I've learned that. I don't get excited anymore. I just think I'm gonna die because life isn't anime, apparently. Keep taking those sugars and I don't think you're gonna win at all, bro. You might be dead by the next episode. He looks like a happy fry. Like you know those smiley fries? That's what he looks like right now.   He definitely gets down, bro. Two kids? Oh, I bet he wants another one. Better hurry up before light kills you. He's gonna jump out the window. I wouldn't trust him by a window, man. Look at them. Ooh, I love that connection, man. The way they do that. Oh my god, I thought it was Aaron Yeager.  You know what, man? You should kill her so she could be with Ray. Go actually just do it. You already know her name. Man, I just realized that. What if you kill a girl? And I don't think he's done that yet. But what if you do? Like, would their name philosophically changes once they become married or something? Like, you can't put their maiden... or do you have to put their maiden name? No, I actually want to see how he kills her. That sounds crazy, doesn't it? Man, I feel like I'm becoming light. The light is coming through in my name. Does Ryuk sleep when he sleeps? Or does he go back to Shinigami, bro? No, in Japan, in anime, they will answer that somehow. I bet I'll know Ryuk's sleeping pattern by the end of the anime. What are you doing? Girl, what are you doing? That's your brother! She better not be talking to light right now.  What are you doing? Y'all knew exactly what you were doing with this shot right here. She's like four years old, man. Come on! Can y'all hold back for a minute? Fuck, I can't get my water. There we go. What are you doing? She's like four. Why do you have her like that? She looks like a dog. I feel like...  I bet... I think she likes you, light. I'm still trying to wrap my mind around how we knew how to do that.  What are you trying to do to me?   On the train, moving. Thinking about her dead husband. She's my type. I love girls that were all black like that. Little emo girls. Ooh. That sounded completely weird. Little emo girls. By little, I meant like... Not like age-wise. I meant like smaller than me, okay?  What a coincidence. He always looks stunned. Ryuk is literally me watching anime. Damn, girl!  Talking about Kira out in public? Like he's not right behind you.  Why are you just saying his name casually? Like, write their names in the book.  Light, what are you trying to do? You just killed her husband. Now you're trying to get in her shorts? Probably can.  Yagadik. Y'all are saying Kira and you just said he helped you on a murder investigation. Now you're saying, Shhh, don't say that. Light, you are a sus, man. You're supposed to be like in sixth grade, Light. Why does he do that, man? His voice is always like, Hello, my name is Light Yagami. And then when he's talking to someone else, he's like, Hi. Hi.  Who's this cheery guy? Yo, imagine he sleeps with her before he kills her. God damn, Light. He's gonna lean over to her while they're sleeping together.   He timed it to the moment he climaxes.  Oh, no. Why is he laughing? You know something. You know too much. You're definitely dead now. You know too much. You won't live to tell the tale, woman. Good luck you making home from his walk. I don't like this. Light's way too good at lying, man. Is she like hiding things from him? Because she sucks? Oh my god, girl.  Where are you an FBI agent? Bro, that's why Japanese is so much better than English. Like, in terms of like anime. Imagine them translating that, Ray Pember. Ray Pember. But Light was like, Pember. Like, it just adds that dramatic tense to it when it's said in Japanese. I bet you're sorry.  She knows too much. She's dying. Very soon.  He became a Sith. Why are you letting him walk behind you?  We don't do that in America. We don't walk behind people while we jog. That's us. Who knows what this guy's doing behind you? Oh my god, bro. She is banging, though. Damn. Oh, black with the boots and everything, man. It's hard in this show to hit somebody. Bro, you better have had action that night, man.  But yeah, you better have gave him something before he died. Or my dude is in heaven right now just crying tears. That's gonna be the rain tonight. It's gonna be raised tears. He's having alcohol too, bro. He just got it on. Oh. This is gonna be the first woman that life kills. And I'm so intrigued.  Oh no, not the light death music. Would he change her hair color into death? No, his hair's red. That's so mean. Oh no, she's dead in the next one, definitely. For the first time ever, I'm gonna watch the preview for next week's episode next week. Next time I react, let's see. Let's see what happens next week.  She's sus of him.  Wow, so that was an episode. I like this girl, man.  I know she's acting out of revenge because her fiancee died. I understand. That conflicts with her intelligence at times. So she'll spew things risky without caring what happens because she wants to come to the bottom of this. I understand that, but she's hot, man. I love that old black fit.   What I'm mostly interested in is seeing how he's gonna kill her with the whole thing that I mentioned. How... Like a woman changes her name when she gets married. Most of the time. Sometimes they keep their name, but what if she does? Like, how does that work in a death note? Do you have to write their maiden name or whatever? I'm sure one of the middle title cards said that. I just didn't read it. Nick, you're supposed to read it.  Anyways, I love you guys so much.   I'd literally kiss you on the cheek because if I said anything else, I'd probably get mass reported. But yeah, that's gonna be it for today's video, guys. I love you so much, and I will see you all in the next video. Do...