Marcus, can you tell us a little bit about the limitations of the PLI method in terms of mechanical limitations? How thin can you slice the data and how do you then you have to appeal to optical approaches? So just talk a little bit about that. Yeah, so the mechanical limitation to date is about 50 micron thickness for the large slices. I think for mice and red we could go down to 30 micron with the PLI stuff. It is important that we have a large signal as large as possible and the thicker the slice, the larger the amplitude is. So this is another technical issue. Clearly from the PLI point of view we would also like to to understand what's within one of these voxels. So we have started collaborations with people from Florence, from Lenz Institute, and they are doing optical fluorescence microscopy to photon microscopy on the same slices so that we start to learn what's even within our small voxels. And there's a lot of work going on towards this direction and it is clear that all these very high-resolution data sets there will not be acquired for the whole human brain. But we would like to understand what's what's within a section thickness of 50 micron still. In addition if you would like to to understand how the cyto architecture looks like in the brain, I mean the the big brain gives us information about the the localization and the size of the of most of the the cells that currently there's also a lot of work ongoing to understand how can we scan through the different virtual sections. So to come up also with a 3D reconstruction of the cells within each section. So there's a lot of dynamics currently in this field. So in your presentation you I'm interested by the computing challenge associated to PNI. In your presentation you focused more on one of computations like you have to do these computations only once in the data set and once they are done you know they are not needed anymore. Do you also foresee that these data these type of data sets would require computing power on a routine basis like if it would be integrated in analysis pipelines for instance or you know if people wanted to register to this data set. Yes so I had one one slide dedicated to the workflow process and I said that we put everything into HF5 like format and this will hopefully give us the possibility to to make this kind of of provenance to provide this kind of provenance information throughout the whole workflows and doing all these so in the end we will have to provide all this data to the people doing MRI and I think the the registration process itself from 3D to 3D this is something which is currently also being targeted by the human brain project and it's not not really currently in our main focus so that was the reason why I didn't focus on that but we try to take care of all these provenance information also to be able to repeat the same type of analysis after changing a single step in our workflow a single software in our workflow so that it becomes more intelligent that we say okay something in the middle changed which type of data which which modalities do we have to change or re-calculate so this is what we are looking for but we have not yet succeeded in implementing something like this. Stephen let's Stephen have a go first. I'm trying to put what we heard in the morning together with what we heard in the afternoon and it strikes me it strikes me that no one really talked about the morning's issues except maybe Nico I guess we can consider matching the modeling generational models to the data as an example of a form of replication. But no one talked about you're all representing the development of new methods and no one sort of talked about reproducibility or replication is this because you don't consider them important as one of the first steps and we heard about some simulations that there'll be something that'll be done later down the road so should we think about these as very early things that would rule a particular methodology out or a particular software implementation out because it hasn't been demonstrated I'm curious to at the intersection issue between lots of new methodologies and those issues we heard about this morning anyone wants to take that on. So I would like to say something about tractography algorithms and how they are compared and how the results are reproduced it's something that started with the people that came up with the fiber cap data set that I showed at the last couple of minutes so that has been extremely useful in the area of tractography because before that paper before the study there were so many tractography algorithms and nobody knew basically which one is better and how they and I think that helped that study helped a lot to they had a competition basically you know for any different algorithms and for a given data set right for a given particular set of connections and otherwise so I think it helps when communities basically agree to do this kind of competitions by the way this kind of competitions happen all the time in machine learning you know the deep learning community and more generally machine learning community basically they have this annual competitions of envisioning different in natural language processing and so on so I think it's not exactly related to reproducibility but it's related to figuring out what works and what doesn't work and which one is better between this large set of methods yeah I I think the reason no one's talking about reproductions is because they're so boring it's sort of nothing you just showing that what you've claimed before is actually true and of course that's really important but it's also not very inspiring right so we have to find ways of making that part of our workflow while still also keeping our focus on conceptual advances and I think competitions are really a great thing they've really boosted computer vision and this rapid breakthrough with neural networks catching on so quickly was probably only possible because of secret held-out sets that needed impossible to cheat on this and therefore very believable because even in computer vision and machine learning there's circularity going on and overfitting right and but but this is the way to really make that impossible with secret held-out sets and neural science have been a couple of attempts in that direction but it hasn't really caught on but I think that should probably be a major thing to think about creatively how we can make that part of our normal normal work and maybe have annual competitions like that with new data being added on major paradigms that are important and people competing with computational models to explain these dates so in the same sort of vein I was looking to pull together the two halves of the afternoon session more imaging versus more statistical and I'm wondering whether or not these new statistical approaches offer us something new to combine electrophysiological MEG type of data with FMRI data towards giving us better spatial resolution this is an imaging session after all we all know about the the problems of logithetus type problems of the neural data is very different from the vascular data that we draw our FMRI signal from but do nevertheless if we ignore that truth and just try it anyway might we see better spatial resolution in FMRI data being built upon incorporating MEG data with these new statistical approaches we've heard about today or is it a bridge too far and the HRF will kill you anyway well I think that's a very complicated issue I mean yeah vascular responses and electrical responses are not the same thing you know as I also pointed out in my talk there is limitations on the degree to which you can use both signals to say something about neural data and even though this is extremely common in FMRI for example most functional connectivity studies make claims about correspondence of neural activity even though the signals that they're measuring are really vascular signals so it might just be similarity and the vascular response between areas that is driving these similarities I don't know I mean maybe higher resolution data will will help something but I think we should really realize that but this is an FMRI at least that this is a vascular signal maybe the future is really there I think that there are interesting things to say about the brain just from the relationship of about about how neural activity relates to vascular responses and there are many clinical situations where this doesn't work well and where FMRI could play a really important role I would say that maybe there is hope with a new method and that one thing that also avoids this problem with vascular and the confusion of the signals is this focus that I think that really started with NEPOS work on sort of representations and information content rather than just all signals themselves but I think then by relating the information content in different signals or the representational geometry I think Nico didn't mention it today but he has a lot of work on comparing the modalities like this or people have used RSA to do it and I hope that with my method also we can do this looking at redundancy between individual time points either of a whole helmet or a single sensor and individual box or responses so I think that by focusing on this information content representation question that holds some promise. So what would we need to be able to see in vivo blubs and interblubs? Nico. I think the additional element that we need to consider is what is the purpose of all this right for me the purpose is understanding computational mechanisms and that means that ultimately we want models that perform the tasks we want models that are AI systems but that also explain neural and behavioral data and those if we take that to statistics those should be our generative models of the data right and constraining our model search to only things that actually can perform the task is an incredibly strong constraint right so then we don't necessarily need as much data from our imaging technology I think it's unrealistic to ask imaging technologies even to vote on imaging to give us all the constraints for building our functional model of the brain that's never going to work there's always going to be a reverse engineering challenge where we have to build something that actually works and then if we have you know a limited number of finite set of functional mechanisms then we can use forward models that simulate for example fmri data I mean GUEG data and they lose a lot of information but they retain enough information I think to adjudicate between you know a thousand different deep neural networks that do the task. Is there a role for structural priors big brain or PLI type data within functional and data analysis? Definitely I think we need all the constraints that we can get. I have a follow-up question on the procedure for increasing the temporal resolution of fmri because we've decolored before but how was the experiment performed so there was an example that represented a horse and so was that stimulus repeated again so was it the same stimulus that was repeated every couple of seconds or it was a new stimulus and again it was presented periodically so a person can anticipate that the stimulus is going to be presented so does that affect the results? Yeah that's a good point I mean the experiments were done with different stimuli the idea there is that we are interested in the general process of naming pictures or of language production and so the specific type of stimulus that doesn't matter in a sense it's the standard assumption in all experimental designs where you're comparing two different experimental conditions that are composed out of different stimuli but you're not interested in the real form of the individual stimuli you're just interested in the commonalities between all these stimuli and you know so it's that standard assumption I think that is not strange. But then again in another presentation we saw that there were different responses to different kind of images so if you see a face versus if you see a non-animate object so wouldn't that distort the results? Well I mean there might be small differences in the results in the response to say a horse and an animal or a car but I'm not interested in that difference I'm interested in the general similarities between saying the name of those pictures in this particular data set you know what I mean so if I were interested in saying a horse versus saying car I would have to do separate analyses for these two different types of stimuli but because I'm interested only in naming pictures in general I wouldn't do that. I think it's a standard assumption. I was curious about the models you're using and the data. I think we're close to the point where we will be shipping data somewhere to be crunched by some sort of tools and other sort of analysis and all will be like this in places where you send your algorithms out and you know that's how far in your kind of modeling aspects are you from having somewhere like a science gateway somehow where you could put those models and say and tell people hey if you have data of that kind you can try those models on today and how far are we to construct infrastructures where those models can kind of accumulate and sort of be compared like in almost like in the middle so that competition somehow isn't like real competition it's just like okay see the state of the art I'm trying a new model and I'm pushing that to be this infrastructure and so how fun we are because I don't have very much an idea of exactly what you're doing I'd like to see how far you think we are from that sort of endeavor. Yeah I'm kind of dreaming of a website where you can upload data sets brain activity data sets together with the stimuli so you're uploading essentially images because I'm studying vision so images and brain responses together and you can also upload models that process images and when you upload a new model then it's instantly evaluated with all of the data sets that are on the website in the repository and when you upload a data set and all the scores of all the computational models are updated to reflect additional evidence from that model so this would be I think a dream and how far are we toward that I think there's still a number of steps to go both in terms of agreeing with other people working in my field on the data format you know the practical issues it's certainly easier for the field of vision than for all of neuroimaging early on the national fMRI data center failed in part I think because every experiment is very different and it's very hard to find a standard that encompasses all of cognitive neuroscience I think within vision we have a better shot at that and there is a group of people who have been talking about this for a number of years and who love the idea and I think we just have to get our rack together over the next three to five years to actually build something like that. It would be very interesting to see exactly what's needed for that and also be like a focus on your field and then maybe there's an example for other fields to be like a copy-based and adapt I think that would be a fascinating enterprise. It looks to me like there are no more questions I think people have punched drunk at the end of the day so I'm going to call it a day I'm going to thank all the speakers for a very entertaining session thank you very much.


This is St. Tech, Hawaii. Community matters here. I should join her. And this is cannabis chronicles, a 10,000 year odyssey. And so there's so much to talk about, so much to learn about cannabis. And it's this, what do we say, tell me news of that plant of many resources, which wondered far and wide the ancient plant of food, fuel and fiber cultivated for millennia. 10,000 years or more have passed and 50,000 different products made from this plant and all of the uses. And yet here we are just discovering hemp, cannabis, ashes. We talk about cannabis and religion, cannabis and medicine, cannabis and dear old Uncle Sam. And so that's where our odyssey begins, right here in the state of Hawaii with Senator Willis Barrow, who has been a avid supporter of medical cannabis since, what, 2002? Well, I was here in 2000, when that was my first year in the legislature, when we were the first legislature in the nation to pass medical cannabis, a medical cannabis program for our citizens. And you're right though, hemp has so many uses and going back to the 13 colonies who were required to grow hemp because it was an export crop. And they made paper. Right, and so many other products and now we've come full circle. It took some industrialists, rich millionaires to conspire with fake news to ban a product, cannabis. Congress did that through lies and deceit and just telling the American people false information about marijuana, about cannabis and what it would do to society, which was just not true. First fake news, or some of the first fake news. Then we can depend on. But now we're going to start in 2018, a pilot program for industrial hemp, the State Department of Agriculture. And hopefully that will bear some productive fruit and efforts. It has the opportunity, let me put it that way, to create a whole new industry in Hawaii so that we can have something other than tourism and the military. When you think of 50,000 products that can be made from hemp and you have three crops a year, boy, just think what people can create out of that. You know how many trees it takes to create a roll of toilet paper? Can you imagine? This is mind boggling. If we could concentrate on three areas, a biofuel for our energy needs with our vehicles, a construction material, because there is a home in Maui I believe that is built out of hemp. Yeah, and it's called a hemp creek. And then of course the fiber, the clothing. Why can't we have a line of aloha shirts, hemp aloha shirts? I mean, so many possibilities. It could be our next golden crop. It should be. And when you think of ropes, for thousands of years, the ropes, the lines for ships and boats were made out of hemp. And now just think of the industry alone in Hawaii with all of the boats that we have here. It's just a gold mine if you just begin to think of it. Right. And many, many other countries have a hemp industry and it's about time that the thinking of the past ends. And the United States gets into hemp and eventually adult use. When we look at, like I said, this industry and what it can be, you're right, shed that yesterday's thinking and look forward because yesterday's not going to come again. So if we look forward and what it can be, because there are crops now that things now made like the 3D printer. If you made fuel, the oil or whatever it's called, or 3D printer, the 3D printer didn't even exist 20 years ago. So how would we even think that hemp could be a use in a 3D printer? Exactly. I have knees made on a 3D printer. I have two artificial knees. They were made on a 3D printer. Whoever just thought that we could do that. Technology, exactly. It's incredible. But let's talk about where we are today in the state. With the medical cannabis. With the medical cannabis. And for anybody that's interested, the state did decide to get rid of the word marijuana. And so now everything, the medical products, everything says medical cannabis. And I thought that was a great idea the state came up with because the word marijuana has negative connotations. They decided to reach out and come into the 21st century. Yes. And now this year we've had our first medical cannabis dispensaries selling in a retail establishment. I believe there are three operating and eventually statewide there will be 16. With a breakdown of three licenses on Oahu, two on Big Island, two on Maui and one on Kauai. And there's going to be some trial and error as this new healthcare industry starts to mature and become better. But we have I think approximately 19,000 plus patients. And then it's grown considerably in the last year just because people knowing that the dispensaries are going to be available. And they don't have to grow their own like they're doing now. And hopefully the price point will also come down because the supply is limited, especially with just three out of 16. So you know that there's a big gap that needs to be filled. But I expect that as more dispensaries come online, the price will come down. And it's going to have to come down if it's going to compete with the black market. If it's not cheaper or at least equal, competitively there will be people who just may bypass dispensaries and go to the black market if they can save a few dollars. Which basically to a bill I'm going to be introducing that would allow dispensaries to give away medical cannabis to people who are very poor below the poverty line. And they can't afford it if they want it. So that's one of the pieces of legislation that we'll be drafting in 2018. Oh, very good. So now you belong to an organization that meets quarterly about this whole issue of medical marijuana. What is it called? Well, it's the legislative, medical cannabis legislative oversight committee. Oversight committee. So with an oversight committee, this made up of legislators or the public who is part of the oversight? Well, there are four legislators, two from the Senate, two from the House, and multiple, multiple stakeholders. Another 20 or so. They include law enforcement, the healthcare industry, the owners are represented, patients are represented, the university. So you can see it's a gamut of people and organizations that have different perspectives and views and interests in the cannabis industry. So what do you do exactly? We talk about ideas and recommendations that we will be looking at in the 2018 session. And I do have a list here of some of them because we passed legislation now in 2015, 2016, 2017. And we're likely going to again in 2018 because this is a new industry. It's in its infancy. So we're going to learn some things we can do through legislation, other ways the Department of Health can make changes through rulemaking. Oh. But sometimes legislatively it's quicker than rulemaking, which many people know. Oh yes, the Health Department has what is it, 12 to 1900 new card holders each month. And yet they have empty vacant positions and so they're behind. Right. So anyway, the Health Department is always an issue. Next year the law states that Hawaii can begin a reciprocity system program for tourists who come through Hawaii who have medical cards. So I'm expecting that there's going to be legislation that will allow that and set up a process where we can cater to, you know, the potentially hundreds of thousands if not millions of tourists who may be medical cannabis patients. Because they can't carry it across the state lines.  You mentioned that I can see Hawaii carving out a little niche market for medical cannabis patients who want to come to paradise or looking or looking for a place that is friendly to their needs as medical cannabis patients. Can you see medical cannabis resorts? Let's go there. Yes. You know, let's look at Hawaii as medical tourism. Exactly. A healing place. Yes. A place to unwind, to relax, and to get better mentally and physically. And physically. Exactly. So that's another industry we need to look at. Yeah. Medical cannabis resorts and tourism. I can see somebody getting into that in the future. I know the exact place on Kauai, what is the beautiful place that was damaged 25 years ago in the hurricane? Cocoa palms. Cocoa palms is still sitting there languishing. Wouldn't that be perfect? That would just be perfect. Right, right. Okay. Let's go on. Another big issue in the news has been the opioid crisis, especially nationwide. It's been hitting the mainland, the continent worse than here in Hawaii, but it is a problem. And we're looking at legislation that will allow medical cannabis to be used for helping people with substance abuse. Right. Issues or addictions, and in particular, including opioids. Okay. Because people are dying weekly, if not daily. Yes. Opioid overdoses, but not many people are overdosing on medical cannabis. They don't. Nobody is. Nobody is. That's the point. So we need to take a break. Okay. We'll be back in a minute, and then we will talk about some of these other issues on your extensive list here. Very good. Okay. Thank you, Marsha. This is Think Tech Hawaii, raising public awareness. The process helped people of all abilities imagine the possibilities in their lives. I'm Lucas, host of Hawaii Is My Main Land, here on Think Tech Hawaii Fridays at 3 p.m. Hawaiian Standard Time. We explore environmental issues, political issues, keeping it local any way we can. Aloha. And we are back with Senator Will Esparro, my dear, dear friend for many, many years. I can count on him to talk about medical cannabis. Yes. We were talking about this opiate addiction, and what, I guess, what really bothers me about not the opiate addiction. Well, yes, that too. But in the scheduling, cannabis is scheduled at the very top. Schedule one, yes. Opiates, which are killing people, are number two. So how is it that this opiate, which is written, it's legal, doctors write prescriptions for it all the time, it's killing people, but here we have cannabis that's not killing people, that is a schedule one. And we in the state have the ability to deschedule and we don't. Well, at this time, the big issue with schedule one, everybody sees it as a federal issue and problem. With it being schedule one, we're categorized with heroin. Yes. And schedule one is that there's no medicinal value, and it's highly addictive in particular, which we know cannabis is not. It's not highly addictive, and it does have medical benefits. So the schedule one goes back to what we were talking about in the 40s, where Congress passed bills and laws based on lies, false information. And they got away with it, and that's where we are today in terms of the prohibition on cannabis as recreational, except for the states that have done it. So I know there's people out there that says, why you should change it to schedule two or three or whatever the case? And we haven't. And I think part of the reason is because at this time, unless the federal government does anything- But we don't have, we've already, the Supreme Court already decided that. We're moving 100% forward with our medical cannabis program. Nothing's stopping us. Nothing is in the way, the federal government. Unless and until the federal government says anything, we're just moving forward. No. What I'm getting going with that is that in 2006, the federal government, the United States Supreme Court said the state has the right to control its medical industry. And so that takes this out of the realm of waiting on the feds, because you've already decided that. So what is the holdup of the scheduling? It's not the feds. That's a myth. Well, that's a myth that we've already- The health chairman. The health chairs are the ones that would schedule these hearings. And unless there's a large and big outcry to push for schedule one to schedule two, it just hasn't happened. And so we're still moving on. See, the fact that we have a medical cannabis program states that we disagree with you, state of Hawaii, with the United States. Right. And you've already proven that there's a medical benefit and that no one is addicted to it. And in spite of this, what is it called, gateway drug, which it's not. So nobody, nobody has been killed in an automobile with cannabis. Thousands of people are killed with alcohol. Nobody. So what's the nonsense here? It's all a myth. So what do we need to do with what I'm saying as voters, as people with cards? How do we, what do we need to do with the legislature? Because that's where this is now. To move this, so to de-schedule and move on to the next step. Well, I believe there are some in the legislature who don't think de-scheduling is a high priority right now. And that there are other more important permit issues because no one is threatening our medical cannabis program. The federal government is not. They're not. But having, I mean, you know, they're not using the schedule one issue and closing us or 30 other jurisdictions that are doing this. Medical cannabis is here to stay and.  That's what I'm talking about. When you look at the others, even with the hemp program that the state is supporting. They have certain roles and regulations that go back to the feds. That just shouldn't be. That's all I'm saying is how do we move from that stigma to let's get real, you know. That's the issue. Well, we do. So what do we need to do as ordinary people to move this? What do we do? You're the legislature. You're the senator. What do we need to do? Well, like all bills, contact your legislators and contact your representatives, your senators. And if you have a special interest on any bill, you know, let them know you'd like to see a bill heard or drafted or whatever the case may be. And this the schedule one issue has come up sometimes and we just haven't been able to get legislation passed on it. But it hasn't impeded any movement and improvements on our medical cannabis program. But it is a problem with the hemp program. Well, we do have the pilot beginning next year. But if you read the directions in the pilot project, even that because of the schedule one, which is crazy. Right. But they're basing that schedule one on the federal interpretation. Right. And that's why we need to get rid of that so that we can move this project on without that nonsense. And there's some thinking that, you know, until the feds take action on the schedule one, nothing's stopping Hawaii and our medical cannabis program. Yep. And we're not even talking legalization, at least not anytime soon, I don't think. So the medical cannabis is the area we want to focus on in which we are. So let's finish your list here before we run out of time. Okay. Well, there's a discussion on edibles. We don't have edibles. We do have tinctures, lotions, lozenges. But when we're talking about edibles, we're talking about candies, pastries, cookies, drinks. Well, I would think that if you have a child that has epilepsy, you want something that this child can take, wouldn't you? Well, we're close to... Well, I'm talking about... Medical. I'm talking about if you say that this cannabis can control the seizures. But this is a child. So what do you give? How do you give them? No. Let me explain. I'm sorry. This is edibles to be sold in dispensaries. So right now, you're right, many of the patients, they're growing and they're making edibles. And they're getting oils and whatever else they get out of the plant.  Yes, yes. You can put it in an oil form and then put that oil in food or whatever it may be. That's one way. Okay. So insurance reimbursement working group, what is that? Well, patients, since this is a, in essence, a health care issue, right now patients just paying straight out of their pocket cash for this medicine. Whereas in our system, the way we set it up, forgetting about the schedule one. Right. But if it's a medicine, why shouldn't insurance companies give you a reimbursement? And that's what this issue is about. Oh, very good. That getting all the stakeholders, including the insurance companies, and seeing can we add this into the list of reimbursables. Well, that makes perfect sense. Right. So that would be one thought is a working group to look at that. And a working group to look at the, just to get more specifics and details on the edibles. Because once you're talking edibles, you're talking about a place where these items are going to be prepared, kitchens, Department of Health. Yes. So that really opens up a gamut of rules and regulations that's going to have to be followed. But I'm hoping we could get some edibles available at the dispensaries by 2020. But we'll see on that one. Now, this is a big one here. The patient's inter-island transportation, that is a big one. For me, it seems really... Well, it is and it's not. Because if a patient can now get cannabis on every island or eventually, then there's really no need for them to... No need to. But until then... Well, my understanding, and I think we just need to look at this because it's sort of gray, but my understanding is that TSA has not been taking people with small amounts of medical cannabis. So that's good. But we're going to, I think, just make that language stronger. But if you look above there, that's an area that I like to see UH get involved with. Right now, the university, because of the Schedule 1 problem, doesn't want to get involved in any experimentation research that has to do with growing, touching the plant, the seeds. But what I like to see... So if we did the schedule, then they could get into the research. Well, what we can do now is see if the university can partner with the Department of Health. And we could tell patients to give us your information. This is a voluntary reporting. And we can start collecting. So if someone is a patient, they've got this ailment, they're taking this much product or cannabis in this form or that form, dosage, and start collecting and getting a data bank so that once you see research and development getting the green light from the federal government, then we'd be... So that's when we need to get rid of the federal government. We're back to schedule. Okay, I get it. Now, we're back to schedule. Okay. But we can gather data without the Schedule 1 change. Yeah. We can voluntarily have patients give us information about their dosage and how it's helping them. Well, anybody, any research group could do that. It doesn't depend on federal... No, but it would... We'd have to pass a law. Yeah. Let's see. The university, we'd have to pass a law. I understand. But if you were a researcher and you're not dependent on federal grant, you could do this. Right. But we're... Well, yeah, but I'm talking about getting the University of Hawaii involved. So let's... We have a minute left. Okay. Let's... What is this use outside the home? Well, we had a discussion on that on... Right now, you're only supposed to ingest at home. Uh-huh. Right. But what if somebody... And not smoking, but could somebody take some... On the park, you know... And I guess if you're not being obnoxious and rude and making a... I mean, nobody would even know. But just someone was talking about just clarifying that you could if you wanted to go to the park, go to the beach. But you can't if you're smoking. Right, right. But not... Because I'm smoking anything. Exactly. We have our anti-smoking laws already. Yeah. Right, right. So what is discrimination, adult use? Well, this is an area that the Senate has supported in the past, the decriminalization of the adult use of cannabis. Oh, okay. So people wouldn't be going to jail for small amounts. And this is an area that the Senate has supported, but we've had problems passing it in the house. Oh, okay. And usually in other states, they went from medical cannabis to decriminalization to adult use legalization. That's... Okay. So we are coming up on 2018. You will be back to tell us more how we're progressing with these issues. Yes. And how we can help. Certainly. And... So thank you so much for coming again. We will see you soon. Thank you, Marcia. Happy to be here with you. Aloha. Happy...


Hello Snapchat! My name is Kelly and I'm an IBM Research Almond. We are getting ready to celebrate our 30th anniversary tomorrow. This is our auditorium and tomorrow at this time we'll have our clients, partners and researchers present on their innovative projects to an audience of about 200 people. So excited for tomorrow's Almond's 30th anniversary. I'm going to be talking about how I use sequencing data to save people's supply chain. Hi, this is a selfie. We want people to come in, swap their cheek, we show them the shape of their cells and give them a souvenir. It's the night before our 30th anniversary and the lab is full of people setting up demos. Can't wait to see them all tomorrow. Did I mention we're all buzzing with anticipation? Hope you're going to be here. And with that, preparations are mostly completed for today and I will see you all tomorrow morning bright and early for Almond's 30th anniversary. Good morning Snapchat. It is quite bright and it is quite early in here at the Almond and Lottie. Our guests are starting to trickle in. Today is the day. Here at the IBM Almond Research Center, 30th anniversary. Not looking back, looking forward. Exciting times and having a great time. Hi, I'm Anish Krisman and I won a $20,000 AT&T Havocon and I feel like this event helps people like me prosper. Provides of data or puzzle pieces and distilling those into lists of thousands of microbes or puzzles. I'll never forget those vivid images of a quantum corral where individual xenon atoms were moved on a surface to form a ring. Blockchain, artificial intelligence, data, all contributing to the 30th, one in honor. I think it's very powerful for that. Nemo is one of the many research demos that are being displayed right here in the ad lab. So we have SIDAPI match. We'll take your touch data at the input. So I'll put it in your mind. This SIDAPI is the most similar to the inputs upon that. And here we have Jeff Welzer, who's Twitter is a 92% match with Mike Bloomberg. They are curious, organized, and also very similar to Snoop Dogg. Imagine taking an instance of Watson and literally putting it in the world, giving it eyes and ears and arms and legs. This is in body cognition. So the lab is mostly empty right now as most of our guests have left. Thank you so much for joining me today and celebrating Almond's 30th anniversary with me. Goodbye Snapchat.


up y'all. Oh look out Bowie. So I got a bunch of purple sapphire in and it's one of my favorite colors. So therefore we're doing a purple sapphire geo today. And unlike usual where I always go with a gold accent. I'm actually going to this time. I'm going to do silver. So move some of this and this. Boom. All set. All right. So what's up Shelley? How are you today? I'm going to be pouring on one of our geode freeform shapes. This and the colors I'm going to be using can all be found at artistilldebt.com if you are interested. It's up TGs, Carol at Mac, Sue. You guys having an awesome day? I really super hope so. Okay. I'm going to start with my fire glass as I always do. This is my one inch of fire glass that I have on the website. I also have fourth inch if you're so inclined. This is going to fill in the bottom of my Druzy. I'm going to be teaching these in person in Pasadena at the end of this month. I think I have two seats left if you want to join my class. Details can be found at artistilldebt.com. So okay. So my resin out of my this, my resin mixer, I promise as soon as I know more about, as soon as I know more about the stand and the complete kit for this, I will let you guys know. I know you guys have been waiting patiently for it. It's my new favorite thing. I think I would probably give up my flat iron before I give up my resin mixer and stand. I'm not trying to brag. I'm just saying that as soon as it becomes available that everybody should have one. Oh, key, dokey. We have resin. So let me go over the colors. I'm going to be using Milky Way. I'm going to use Silver Shimmer by Color Obsession. I don't know. I don't know. I don't know what you put in here to make it so magical, but it's in there. Look at that. It's just almost like glitter, but it's not glitter. I don't know. Beautiful pigment. I'm going to be using Titanium White from Just Resin Color Session Purple Topaz Tint. Not going to focus, but you get the idea. And one of my all-time favorite colors has been for Forever. It's purple sapphire from Resinart. Okay. Doesn't look like the most amazing thing right now. Well, it still looks pretty cool because it's a dry paste, not exactly a mica. So it kind of has a consistency of wet coffee grounds. When it gets in a resin, you're going to be like, oh my God, I got to have it. And I have it on my website right now. So it almost just sounded like a wreck outside and it distracted me if I'm on this. Definitely fully distracted me. So we did that video yesterday of the new colors that I have. And you guys loved all of them so much that I underestimated the number of individual units that I need of each color. So I have more on order already. So let's start mixing colors. That's going to be my purple sapphire. And I want a good sized purple topaz. Whoops. A white, the silver. So weird for me to say silver instead of gold. What else do I have left? The Milky Way. And I have a little bit left in my cup unless, nope, just in case there's something else that I want to mix up, which almost always happens that I want to mix up something a little bit more. So we're going to mix my favorite color first. I'm going to use one of my handy dandy stir sticks feelable on our website as well. It's such a fun texture. It's almost like wet sand. I don't know what kind of magic she puts in it that makes it a dry paste instead of just a regular mica, but it's in there. Something's definitely different. Some kind of binder. No idea. Also, don't judge me, but I always overload my powders. Dry paste or otherwise. Look at this color. Just wake up. How easily is dry paste mixed into resin without puffing up in your face? And now I have this awesome, like neon-y violet purple color. When you get a second, I want you to come tell me what you think of this color. It's almost like velvety looking. Not going to focus because that's my life, but or don't look amazing. I saw that from 20 feet away. That looks like a candy, candy, purple. It almost looks a velvety. That doesn't look like that, but that's what it is. Purple sapphire. Love that color. I just wanted justification on the fact that that's a bomb color. So thank you. Come back soon. Now let's do the silver shimmer. And this looks like I've melted down aluminum and put some kind of glitter in it. But this is just how the paste comes. And I love it so much. So is Jeff going to do some airbrush tutorial? I got an airbrush for my birthday last month and I want to try it out. Yes, he actually is going to be doing that soon because he just made a bunch of stencils and something else. Oh, yeah, he got a bunch of hats to do. So that will be happening soon. So stay tuned for that. Okay, so the next color I'm going to do is titanium from just resin. It's my favorite white for oceans. And a lot of other just white things of all of the whites that I use this one I think has the most titanium base in it because it stays or has stayed wider longer than my other whites that I have on paintings on my wall in my house. It's very heavy. So it sinks really well if you like to create lines and things, which I'll do in this video, but it's super opaque as well. Love it. I need some Milky Way. That's too much. It's too much. Oh, wow. Just may not be as translucent as I wanted it to be. Or maybe we'll just put our leftover. I left over clear in it. This is what happens when you use too much of it. It's you almost can't even. Well, you really can't see through it that well, but you can see the super sparkle on it since my camera won't focus. It almost looks oystery. Got that in that. And then lastly is the purple topaz, which is a translucent tint. So I only put very little amount in here. And if I were to put more it'd be a deeper shade, but it would still be translucent, which is one of my favorite things about it. So that I think is going to be a great see through complimentary color to the purple sapphire. It's almost the same. Luckily I have a backup. I don't know why I keep dying. Not that old. Anyways, I don't know if you heard me, but the cradle board is from our website. And it comes with the center already cut out and inset. It's like this. And so I fill it with my fireglass. And then yeah, so it's really not easy to cut out the hole and patch the bottom and fill it on your own. So we try to sell these already prepped. Oh, you fell in love with the Milky Way. You weren't expecting the results you got when you mix it with resin. It was more sparkle than you plan, but you weren't upset about it. How can you listen sparkles always an option? In my opinion, anyways. Okay, so which one do we want to put in the center? I think I'm gonna put silver in the center.  So I'll order some other I'll have these on the website this weekend. I must always start with a metallic in the center, whether it's a gold or silver, copper, etc. Also, my process for geodes is to put the color down and then fill in the areas like between the colors or for this one, it's going to be just fill in this void. And that is because when you lay a resin out, especially if it's colder or it's a thicker resin, it's going to want to lay out at like a quarter inch. But resin likes to level off at an eighth inch. So if you just poured color out and just filled every gap, then it's going to self level a lot of what you did off of the piece. But if you just put the color down and fill in between the colors, then you don't really have to worry about that because it'll self level at thickness or height that's closer to an eighth inch than what it would have been if you just left it at pouring a line and a line and a line. I hope that makes sense. If I can zoom you all in a little bit. Hey Evelyn. Okay, so the next color I can't wait. I'm going to have to go with the purple sapphire. As you can see, I poured separate from my first color and I'm just going to fill it in. This will save me on resin and frustration from when the resin goes to self level. If I put too much resin on, it's going to find its way off.  It just is the science. And so it's going to find its way off in just one area. And so everything that you've done will have stretched only to that one area. Very frustrating. I only speak of my own experiences. So to circumvent that, I started just doing this and it's worked out really well. Also very proud of myself for using the word circumvent. I also lay my colors down and kind of an accent to the shape of the board that I'm using. So I've come up higher here because this part is taller. And then I'm going to come out more down here for the same reason. I'm also going to vary the thicknesses of my lines because that's going to look more natural. Okay, I'm trying to decide if I want to do the translucent purple next or if that will be too much purple next to each other. I don't feel like it will be but what do y'all think? I know this purple is one of my favorite purples of ever. I haven't even done anything to it yet and it just looks good just because. Yeah, I was thinking white as well. Probably need a balance on color. I'm going to do a thin line of white. But even when I do just thin line I'm going to pour the line out a little bit separate from the color before it so that I can fill that in. Also this table is not level. So I anticipate some color traveling before I'm ready for it too. I got a little bit of purple on my glove and it kind of moved out right here but that's okay. Because I'm going to manipulate the colors after I get them down anyways. I think. A lot of times I'll do a full swipe but I don't know if I'm feeling that on this one. I'll probably wait till I'm done adding the resin before making that decision but what do you guys think? Should I do a full swipe or just use a heat gun? Don't forget that next month we're starting our pour with us kits and very excited about that. The first one we're going to do is a white and gold marble since so many people liked the marble videos that we've been doing lately. I think I'm going to have to make more of this color. This is the translucent purple. The tint. I don't know what's going on with my stream today and yesterday but I appreciate you guys telling me in the chat what's happening. I'm glad that the video righted itself before I got another angry text from damp saying that something was wrong with the feed because that happens when something's not right. I hear Jeff's phone go off. That's how I know to check stuff because that means vamp or Clara is messaging about something not being right. Have an awesome day Donna. She's in the future. Hope I made enough resin for this. I only made six ounces. Okay so I'm going to do actually I'm going to need I think I need a darker purple so I'm going to mix up another color. I'm just saving some of the clear so I need a darker color. Let me see what we got here. I was going to grab an abrogene abrogene abrogene. Nobody can help me ever say that word because I can't say it. Abrogene I don't know but I'm going with berry from color passion. A little bit different tone of purple. It looks a little bit dusky compared to everything else so I think I'm going to add just a little bit of ooh I have some Jackie Shimmer over here that I'm going to add a little bit to this. It's going to deepen my purple in theory. If we don't like the color we're just not going to use it. Yeah I think that Jackie cooled it off enough. In any case we're going to use it. I'm going to go with it. I just need something just a little bit darker here. Kind of excited about how long I pulled this line for. I'm just going to scoot it all to the front of my cup and pour it out because it would take way too long to stretch that line that far. Again right all right all right all right. I should make some Milky Way into solid purple. I'm going to give you guys a close-up of this in just a second because you can see it's really neat the sparkle of the Jackie Shimmer from color passion. You can see it in this dark purple that we just added. I don't know if it's going to be visible on camera but we're going to find out. Oh yeah you can see it that Jackie Shimmer sparkle nice. All of the colors that we sell on our site all 800 of them can be mixed interchangeably super cool.   It acts as a glue and also it helps to allow my glitter glasses I'm going to add to stick. Milky Way like candy bar like a color I like the galaxy all the things of Milky Way and since it's still a bit translucent you're going to be able to see that dark purple that we made under the Milky Way if it shifts over it which it probably will because my table is not level. I got some purple in my Milky Way but that's okay. Nothing in nature is perfect and honestly once I realized that doing geodes were a lot more fun because I got really caught up on it being perfect. I'm going to do some more of this banging color. I'm just going to use my finger for this one because I already have purple all over my fingers. I'm going to make this the last color all the way around to kind of frame it in that very vibrant purple color. If I had like a chocolate mixed up I would do that for the outside edge but since I don't I'm gonna just enclose it with this color. All right I'm going to put some of this Milky Way into the silver because I'm going to need more silver than I will Milky Way and the Milky Way is mostly clear and this silver with a rainbow sparkle in it would be kind of beautiful probably anyways so let's just see. Yep just as pretty but now with a rainbow sparkle I may do this all the time. I'm going to just put this down on the rim of this lip because I want it to run down into the glass so that you can't see the color of the wood there. And I'm going to save the rest of this to put a line of silver after we decide what we're going to do with the rest of it. So hello Angela, hello everyone. I agree it does need more silver and I will be putting more and more silver in just a moment. So now I need to decide what I'm going to do. Should I full swipe? It's kind of what I'm thinking. Doing a full swipe just it's easy to do and I don't have to overthink it and it just melds all the colors without stressing about like fluidity and making sure everything that I'm doing makes sense for the piece as a whole but what do you guys think? I should have just spray painted this inside silver but live and learn. Well I'm glad you're here Emily. Angela I do sell the geoboard but I may be out of some of the sizes but yes and I'm getting some more in this weekend. Hi Jerry. Okay I think I'm gonna full swipe. I need a swiping paper. Found one. So I'm going to just heat with my torch. Pop all the bubbles and make my resin just a little bit more fluid because cold resin doesn't like to move but I'm not trying to liquefy everything because then all my lines are going to get fuzzy. So essentially when the bubbles are done popping now you can see the little bubbles pop in the surface. When that's done you're ready to go. Yes uh the middle is hollowed out but it does have a base to it but it's not a hole it's just it was a hole but there's backing on it and that's how it comes yes. Okay so I'm gonna just tear this down a little bit because the less amount of paper I have to control the better.  It's a little bit more difficult on a piece like this because the size of the piece varies so you're always adding some of your swiping paper going off the board or coming back on. I'm not adding any pressure I'm just keeping it intact.  I love adding a little scallops like this but up to you. What do you guys think? I'm gonna hit it with some heat not too much I don't want to melt and move everything too much. Now I'm gonna add another line of silver I'm just draping it as I go so that it kind of accents the design we already have going on. Ooh I pulled that all the way around I am proud of that. I think I'm gonna add a rim of white as well just a thin one oops man I can't wait to get you guys up close for for this there's so many interesting things happening up close that you guys don't even know about yet. I think I'm good with how that looks I just need to add some glitter glass which you can get from me on my website artistalldebt.com or from Meyer Imports. I have a code somewhere down in the description for Meyer Imports but also I have a sale on my website right now using the code RESTOCK this weekend will get you 10% off. And the glitter glass is just super fine shards of glass but because they're so fine and they lay in all different ways it gives a sparkle because it's kind of faceted. How sharp is the glass it it will cut you but if you respect the glass and aren't easy with the glass you don't have to worry about it but it is glass and if you get crazy I wouldn't recommend petting it how about that I think I love it I'm gonna give you guys an up close before my phone dies because I think that may be some of the issue okay about that all right so here is the board with the artwork on it I don't know if you guys can see these subtle cells you can kind of see the scallop of them on that edge but because we did a full swipe we have that like gradient ombre between the colors there's some more of them and as this piece settles and self-levels just on its own oh look there's more I can see um the cells will grow that looks so pretty what's up JJ and then the glitter glass on top of the fire glass just gives a bunch of extra sparkle down there and I love it I'm teaching this and Jerry I don't think I don't think so well touching or torching torching will make the cells grow a little bit because you're thinning the top area but I usually don't want too many cells in my geodes but anytime you guys request cells I'll make it happen we'll put some right there how about that right there so I'm teaching this class in Pasadena or the spinach geodes in Pasadena at the end of the month I have on the website all the class information and if you're interested in these colors they were silver shimmer from color obsession titanium white from just resin the vibrant purple here is purple sapphire from resin art the dark purple is berry and jackie from color passion and the super rainbowy sparkle is a milky way I also used a small geode board and one inch fire glass and the large size glitter glass all of which are available on my website artisttilldeath.com and I love it what do you guys think comment down below Julie I reshipped your parcel I don't know why the other one went rogue but anyways let me know what you guys think of this geode if you like the video and think it's worth sharing please do so subscribe if you haven't because I mean you're here watching so you must like it a little bit those cells are so fun and these ones that we put down here so yeah you guys are amazing I am going to go plug my phone in before it dies but I'll let you say hi to Bobo before we go go beep beep beep and also we're doing the pour this class at the end of next month I already have the first one live it is going to be a marble you want to join us you can use your own materials or you can purchase the all together kit that we have available on our website and yeah we'll see you guys on the next video till then be kind to one another because you never know what someone's going through and always remember we do the test so you don't have to yes my precious little boy I'm an amazing little pupper all right you guys see you guys next time bye he said bye


Hello, this is Doja Cat. You gotta see this setup, okay? You think I'm a professional by now? This is being held up by a great Amazon Prime box right now. Hi bitches My name is 45 degree angle today. Some of y'all last week said that my hair color turned out purple instead of silver. Bitch Try me.  What is this video? Like I don't know why you still watch me. I don't know why my professors watch me, too Like what do you think of my videos of me? Also, there is an update to the merch website You probably saw a few months ago. I tweeted about it and I made a video sort of about it I was trying to draw some sticker designs for you guys and I don't have them with me But here they are because they're still being made right now I'll be able to show them on Instagram at some point so you can see them if you don't want to buy them Immediately, but it's just another alternative to getting merch in case you don't want to spend more on a hoodie I know everyone has different price ranges So hopefully this gives a variety of things another thing There are still some less than three pins that are being discounted for like $7 right now And lastly, I got a few comments saying that they wish they could buy the digit hoodie But it's a little bit too expensive So I asked my amazing manager and he lowered the price and I also asked him to drop the other ones But he said those already dropped as far as we can go Frederick stop dropping it Hopefully that helps some of you guys out TikTok I unironically watch it now I don't say that proudly and honestly I would not have made this video if my friend did not buy this wig right here because the moment she bought it I was like that is that's doge a cat, but I just wanted an excuse to wear a wig in a video Yeah, I'm gonna turn to an eagle even though Jenna Marbles has done it and some other people that I don't feel like naming have done it I've turned to an e-boy before and I'm not gonna watch a tutorial on how to turn to an eagle because I see them on my for you page every goddamn day I see them around the streets every day They they all look at the same and I don't mean that as an insult I think the look is cute, but somebody all got a shop at different stores like come on Like I'll give some credit some credit to the e-boys they at least can dress differently even though they all still look bad but e-girls I They're kind of wearing the same outfits and I think you should change it change it up Please so the first step is to have clear skin and I'm not putting on foundation because I don't want to and plus my skin's been I'm peeking honestly. Okay. I'll just say that this is the best my skins look in a while But I am going to first start off with the eyes their eyebrows I don't really want to glue them down, but they typically do like a straight brow They cut off the tail and just shoot it straight up like it's like it's a rocket going into space So I'm gonna see if it's possible to make this eyebrow go diagonally. We're also gonna There I need to glue that part down. Don't I let's just ruin my face or here might as well and only glue this one down All right same to the other side I'm not shaving this off because my eyebrows are one of my favorite things about myself And I'm not willing to sacrifice them for the sake of a video yet We're getting there. All right, we're gonna do like three layers of glue Why don't I just like take a chunk see that I'm just gonna take that big chunk put it right there same thing right here Okay, before that dries you have to powder this down and just powder those ends. Oh that already looks oh Yeah Hi mom once you've powdered you put on foundation. Oh my pants. Oh god. It's actually working Oh, why did you have to work then you powder it again back to foundation and let that sit and while we're waiting I'm gonna take five minutes to sit back and contemplate my decision for ever doing this video All right while that foundation sits on top of my skin like icing on cake. I'm going to Do my eyelashes. I don't have mascara because I Abore the feeling of it. So I just have eyelash curlers Yes, it's from Muji and I'm gonna see if I can make myself have eyelashes guys I've been using castor oil on them every day So if these don't become visible I will make a video about getting eyelash extensions because I just want to know I don't know what it's like to be able to feel my eyelashes on my lid. Ow. Ow Am I a pretty girl yet? Okay other side ow ow. Oh my god. Oh My god not gonna lie kind of wish I had eyelashes still so this foundation has set take a look back What would you like this look on me? All right now?  Yes, just like that this line up bro Okay, not not Terrible. Oh god. How do you end it? I just don't know sir. No, no ma'am Let's just make it ten times worse. It's a liner. It has some hair strokes into here. You know, we're microblading now Oh god. All right, let's keep going. You know my roommate walks in on this and then he decides Frederick I don't think we can room anymore. I wouldn't blame him. I would not be able to put up with this All right brows done sort of oh Oh my god, when I move on hi, I'm mad 24-7. What's your name? Okay onto eyeshadow in my experience They always go for purples or dark pink we're gonna first start off with a transition shade and by the way I'm not gonna try to make this amazing if you wanted a tutorial You could have easily gone to any other beauty guru channel. This is just meant to be fun We're gonna start off with a base shadow of just pink We're also gonna take that pink and just put it next to my sideburn anyways because it's gonna go that far Don't lie. You've seen this that could be a good blush now They think about it when do a reflection across the y-axis on this side only reason I'm talking like that is because I just took a physics quiz Which by the way our teacher is so oblivious to these two Chinese students in the back who just speak the answers to each other in Mandarin and um, I will admit I do listen sometimes because they they do give the right answers in Chinese Honestly, not too mad about that.  Have I caught myself that yet? Oh, I want to add that to the list. Alright, let's talk about tiktok though I talked about e-boys in the past and I still stand by my opinion on them I don't hate the looks they do it's just the cringy shit that comes with the look like I feel like every time I see an e-boy they're either rolling their eyes or biting their lips It's like a circus act like I get the same thing every time this purple shade is terrible Honestly, I would not expect it to be good though because this is this is elf and this is also probably expired And I'm not a makeup artist, so don't expect me to do anything good By the way if you're watching this video the day comes out I should be a u-pen right now doing an art workshop for one of their classes It's sort of like having a motivational speaker except they asked me to not just speak but do something fun I was like, I don't know what to do What do you want me to do play piano for them? Like I'm not gonna teach them to paint because I can't even do it that well and then my friend said Oh, try acrylic pouring because it's easy.  That was not a right choice. I regret my decision to put black in this look I just realized it's patching up here because that's where my eyebrow should be. Okay, whatever. I don't care too much All right, we're gonna keep going.  I like that look To an extent because this is my glossy blush.  Who wants to go out looking like this way too much guys Y'all putting way too much on okay. You do not need this much. This doesn't look like I'm sick It looks like I'm being doused in Cheeto puff powder. It's not just one blush. It's two. Okay. It's uh, BAM BAM am I exaggerating this for the sake of getting my point across hell Yes, but have I also seen e-girls who genuinely look like this?  Why not? I also wonder like how long are people gonna look like this? What year are we gonna look back and say? Maybe we shouldn't have done middle parts. You guys keep thinking I'm gonna do eyeliner by the way You guys keep saying that in my last week's video you thought that the middle part looked good Maybe my generation is different from this tick-tock generation even though it shouldn't be because we're the same exact age Unfortunately, but we made fun of middle parts in our school. Like if a boy had a middle part That's you before a glow-up that happens girls with middle parts Yeah, it's normal like no one cares about that but guys with middle parts Everyone always said like oh they would look so much better without it and now y'all like the look and maybe it's because I have this Internalized fear of getting bullied in middle school again that I don't have a middle part like I don't want to do it again Next you're gonna put a star under your eye because stars are very hot and I'm Burning hot this Kelvin temperature burning. This is my favorite part of the look I actually think it's kind of cute. I genuinely was debating going to school with a star under my eye at some point like Honestly so close to doing this in high school. Next you're gonna do the mistake of putting freckles on your face I'm debated trying kind of freckles You let me know if you think this look is passable for me because like it kind of looks like acne scars And I just got rid of all of mine and I've yet I have yet to see someone do it naturally Like the best way to do it is to literally close your eyes and do it because then you're gonna just place them in Strategic areas and that's not the goal of freckles.  They just take the same blush and Okay, you know what this also looks like those tiktoks when they do got a secret can you keep it kind of gives me that vibe Let's put on the wig. All right, don't judge how I put my wig on.  Why don't you say so? Didn't even notice this is not me making fun of doujikai. By the way, I'm so sorry.  Yeah, so this is it. Um, somebody we're gonna get off to this Ready, we've snatched. I'm gonna should I could put a shake into the full outfit I should get into the full outfit. Hold on. I got my turtleneck on. I got my rings. I am a cancer rising I'm chinese. I like pandas. Here we go. This kind of looks like the rock and then A mistake. Oh my god, people are watching from outside. Oh my god. Oh my god. Oh my god Don't worry guys. I'm just making a tiktok. Don't don't why don't you say so Didn't even notice vogue secrets Hello, this is doja cat Okay, I gotta take this. I gotta take it off. I gotta take it off If you enjoy this shittiest video, make sure you give it a like leave a comment down below about what video I should do next week Subscribe because only 50% of y'all subscribe and that is what?  All right. I love you guys and everything is less than three


The Tiger financial news network update. Good morning folks. This is Steve Rhodes coming to your live from the shores of sunny Delray Beach, Florida. This is your 9 a.m. update. Oh, let me get the charts out here. Sorry about that. This is your 9 a.m. update. And currently we have U.S. equity futures trading to the downside. You've got the Dow futures off about 100 and 209 points. Nasdaq futures down 178. S&P futures off 40. Russell's down 15. You've got gold off 3 bucks. Silver's up 13 pennies. Platinum's down about 2 bucks. Copper's up a nickel. You've got natural gas up 3 pennies. 30-year Treasury is printing out at 109.10. That's off. Two full points out there. The bond crash continues its way lower out there. And you've got the U.S. dollar index. It's up right now. Let's go take a look at what all this means or what to be paying attention to watch today. The first level is going to be the E.S. minis. We take a look at our 9-panel market update chart. $4253.50. That's the key level. That is a buy the D-point pattern. If price closed below that, inside the E.S. minis, we are headed lower. Spot Boltonix is still above its 50-day exponential moving average. It's always dangerous for the bulls out there because it gives sellers the edge. The NQ, now the E.S. and NQ are the only two daily equity future contracts that have bottom patterns. The NQ has got a TD9 count bottom. That key level of support is $14586. If price closed below $14586, we're going to see an A to B equal CD to the downside pattern form inside of the NQ. What will give things conniptions? That would be the U.S. dollar index. It's got a rose minted indicator top. Price has pulled back so far. It's found support at the top of that daily profile. The key for the markets to really rally, for metals to really rally, should be a U.S. dollar index that closes below $10610. If it doesn't close below that, well, then we have a neutral signal because price will have held support with a top. In the case of gold, you want to see it close today above $1830.90. That's a TD9 count bottom. Price closed below that, gold headed lower. Silver has a wave seven and a TD9 count bottom. Its level of watch is $2085. If you close below that, you're headed lower. Lights we crude should target its daily breakout level, and that's at $7894. Natural gas should target its daily breakdown level, and that's up at $343. In the 30-year treasury, we're at lows out here. It got China just dumping treasuries left and right out there. Folks, stay tuned. Tommy O'Brien is up next. Have a fantastic Friday, and I'll see you Monday, 11 a.m. sharp. Take care, folks.


Yes, hello.  I'm going to tell you about something I did about a year ago, but which, as far as I know, has actually been used. That's the comment from the commit. The idea is that if you want to compare saves of some document as ODF, you want to avoid differences that aren't relevant and don't see the actual semantical differences, if any, because you can use that for instance for regression testing to check that if in two versions of LibreOffice that shouldn't have any semantical differences in ODF output that there actually also are no differences, or check for what changes have been made to the actual contents of some document or something like that. Avoid irrelevant stuff, because normally when we say ODF, some parts with are pretty random, even if you have the same document and just save it using an identical way. To turn on this, you set this horribly named environment variable and as you see the one way is supposed to give you a hint that an ODF save display is not supposed to be used anymore to load into LibreOffice because I'm not quite sure if it actually is total legal ODF or it might have other problems. The two things that this environment variable turns on are it changes the automatic style names because those normally are, I don't remember exactly anymore, but if you check the commit comment it says what the problem is to them and the other one are some IDs in the ODF that are like typically totally random numbers because they need to be because they can be copy pasted into other documents and that's why they need to be more or less unique. So the patch just told the switch turns on that instead it uses just sequential int yards for them and if you want to get more instructions just look and give the log for the commit add. It has a fairly long description what it does and that's all. Questions? No questions so thank you.


Hello and welcome to the session. In this session we discuss the following question which says without using trigonometric tables evaluate the following cos x square 90 degrees minus theta minus tan square theta upon 4 into sin square 52 degrees plus sin square 38 degrees plus 2 tan square 45 degrees into cos x square 52 degrees into cos square 38 degrees upon cos x square 70 degrees minus tan square 20 degrees. Let's proceed with the solution now. We need to evaluate cos x square 90 degrees minus theta minus tan square theta upon 4 into sin square 52 degrees plus sin square 38 degrees plus 2 tan square 45 degrees into cos x square 52 degrees into cos square 38 degrees this whole upon cos x square 70 degrees minus tan square 20 degrees. First let's consider this expression that is cos x square 90 degrees minus theta minus tan square theta upon 4 into sin square 52 degrees plus sin square 38 degrees. Let us first evaluate this expression. Now this is equal to in the numerator we have sin square theta minus tan square theta upon 4 into sin square 90 degrees minus 38 degrees plus sin square 38 degrees. Since we know that cos x 90 degrees minus theta is equal to sin theta so cos x square 90 degrees minus theta can be written as sin square theta also we have written sin 52 degrees as sin 90 degrees minus 38 degrees and sin square 52 degrees can be written as sin square 90 degrees minus 38 degrees. Further this is equal to 1 upon 4 into cos square 38 degrees plus sin square 38 degrees. Since we know that sin square theta is equal to 1 plus tan square theta so from where we get that's x square theta minus tan square theta is equal to 1 so in the numerator we have got 1 then again we have that sin 90 degrees minus theta is equal to cos theta so sin square 90 degrees minus theta is equal to cos square theta so sin square 90 degrees minus 38 degrees is equal to cos square 38 degrees. So this is equal to 1 upon 4 since we know that sin square theta plus cos square theta is equal to 1 so sin square 38 degrees plus cos square 38 degrees is equal to 1. So therefore we have got cos x square 90 degrees minus theta minus tan square theta upon 4 into sin square 52 degrees plus sin square 38 degrees is equal to 1 upon 4. Now consider the other expression which is 2 tan square 45 degrees into cos x square 52 degrees into cos square 38 degrees this whole upon cos x square 70 degrees minus tan square 20 degrees. Now this can be further written as 2 into 1 since we know tan 45 degrees is 1 so tan square 45 degrees is 1 into now we can write cos x square 52 degrees as cos x square 90 degrees minus 38 degrees into cos square 38 degrees this whole upon cos x square 70 degrees can be written as cos x square 90 degrees minus 20 degrees minus tan square 20 degrees this is further equal to 2 into sex square 38 degrees into cos square 38 degrees upon sex square 20 degrees minus tan square 20 degrees since we know that cos x 90 degrees minus theta is equal to sex theta so cos x square 90 degrees minus 38 degrees is written as sex square 38 degrees and also cos x square 90 degrees minus 20 degrees can be written as sex square 20 degrees so now this is further equal to 2 into 1 upon cos square 38 degrees into cos square 38 degrees this whole upon 1 since we know that sex square theta is equal to 1 plus tan square theta so sex square theta minus tan square theta is 1 and also we know that sex theta is equal to 1 upon cos theta so we have written sex square 38 degrees as 1 upon cos square 38 degrees so we are left with 2 upon 1 that is equal to 2 thus we get 2 tan square 45 degrees into cos x square 52 degrees into cos square 38 degrees this whole upon cos x square 70 degrees minus tan square 20 degrees is equal to 2 so this is the given expression this would be equal to value of this expression which was 1 upon 4 plus the value of this expression which is 2 so 1 upon 4 plus 2 this is equal to 9 upon 4 so 9 upon 4 is our final answer this completes the session hope you have understood the solution of this question


When you mean banking, I find that sometimes it's not only payment system. You think that there are lending and other stuff on banking, not only payment system. So you think bank can still add value trust on the layer of payment system on Bitcoin? For now, yes. But I think a much more fundamental change is happening in lending. Fundamentally, and this may come as a shock to people, banks don't lend money. They certainly don't lend their money. They lend your money. For that privilege, they give you 0.0001 APR while they charge the borrower 29% compounded. That's a nice business to be in if you're an intermediary. I think lending itself is changing, not just because of Bitcoin, but Bitcoin and other currencies will accelerate it. I think we're going to see the emergence of massively global peer-to-peer lending. I think that type of peer-to-peer lending will require a lot less intermediation. Will banks still have a role to play? Absolutely, I think they will. They can act, especially at first, in their transition period, as guarantors, as underwriters, as providers of reputation metrics, and things like that, that are required in the early days of the system. Over time, their power will be diminished, and their profit margins will be greatly diminished. Until what comes out at the other end doesn't look anything like what we understand to be bank-based lending today. But it might still be a bank. It just won't look like a bank. Just like firm companies today are internet service providers. I don't have to pay five euros to call my family for ten minutes on a payphone. They didn't go away, but they lost a lot of their power, a lot of their profit, and a lot of their control in the process of transforming themselves into what they are now, which is unrecognizable in some ways from what they were then. Their business model is not a pay-by-the-minute anymore. It's a monthly rental basis. They have a lot more competition. That competition is getting global. Some of the biggest providers today are companies that weren't firm companies in the past, Google, Apple, etc., that have a lot of control. We may see, for example, in the future banks will exist. They will offer a lending function. It will be a very different lending function. They will be competing with companies that were never in that space. Maybe Google, Apple, Facebook, or maybe one of the companies incubated in one of these startups.