what causes peripheral neuropathy
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Overview Not a single disease, peripheral neuropathy is nerve damage caused by a number of conditions. Causes of neuropathies include: Alcoholism. Poor dietary choices made by people with alcoholism can lead to vitamin deficiencies.
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Pain arthritis neuropathy Metabolic and endocrine disorders impair the body’s ability to transform nutrients into energy and process waste products, and this can lead to nerve damage. Diabetes mellitus, characterized by chronically high blood glucose levels, is a leading cause of peripheral neuropathy in the United States.
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Foods That Aggravate Peripheral Neuropathy Peripheral neuropathy is a condition in which nerve damage triggers a burning, tingling or numb sensation in your hands and feet. The specific cause can be difficult to pinpoint, but contributing factors include vitamin deficiencies, traumatic injuries, diabetes, alcoholism, infections, kidney disease, tumors and exposure to poisons.
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Pain arthritis neuropathy Peripheral nerves send sensory information back to the brain and spinal cord, such as a message that the feet are cold. Peripheral nerves also carry signals from the brain and spinal cord to the muscles to generate movement. Damage to the peripheral nervous system interferes with these vital connections.n many cases, however, a specific cause cannot be identified. Doctors usually refer to neuropathies with no known cause as idiopathic. Causes of acquired peripheral neuropathy include: Physical injury (trauma) is the most common cause of acquired nerve injury.
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What Causes Peripheral Neuropathy? The peripheral nerves relay information from your central nervous system (brain and spinal cord) to muscles and other organs and from your skin, joints, and other organs back to your brain. Peripheral neuropathy occurs when these nerves fail to function properly, resulting in pain, loss of sensation, or inability to control muscles.
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New clues to causes of peripheral nerve damage The most common cause of peripheral neuropathy is diabetes, which accounts for about half of all cases. The condition also can occur in cancer patients treated with chemotherapy, which can damage nerves. In the body, Schwann cells wrap tightly around nerve axons, the fibers that relay nerve signals.
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Peripheral Neuropathy There are more than 100 types of peripheral neuropathy, each with its own set of symptoms and prognosis. Peripheral neuropathy has many different causes. One of the most common causes of peripheral neuropathy in the U.S. is diabetes.
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peripheral neuropathy Peripheral neuropathy is a widespread disorder, and there are many underlying causes. Some of these causes are common, such as diabetes, and others are extremely rare, such as acrylamide poisoning and certain inherited disorders. The most common worldwide cause of peripheral neuropathy is leprosy.
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Peripheral Neuropathy Explained Updated September 25, 2016. Peripheral neuropathy is a medical condition caused by damage to the peripheral nervous system, the vast communications network that transmits information from the brain and spinal cord (i.e., the central nervous system) to every other part of the body.
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peripheral neuropathy Peripheral neuropathy is a widespread disorder, and there are many underlying causes. Some of these causes are common, such as diabetes, and others are extremely rare, such as acrylamide poisoning and certain inherited disorders.The most common worldwide cause of peripheral neuropathy is leprosy.hen an individual has a peripheral neuropathy, nerves of the PNS have been damaged. Nerve damage can arise from a number of causes, such as disease, physical injury, poisoning, or malnutrition. These agents may affect either afferent or efferent nerves.
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- There are several causes of the nerve damage that can lead to peripheral neuropathy. Alcohol intake could also exacerbate or directly contribute to PN in people with HIV, as can high blood pressure, obesity, smoking, and vitamin B12 or E deficiency.
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- But if you have peripheral neuropathy caused by. 1  Diabetes. 2  Cancer (and you’re undergoing chemotherapy) 3  Shingles. HIV/AIDS or some other immune system disorder.  Exposure to 1  toxins. Gluten sensitivity (also known as celiac disease)  Kidney or liver 1  disease. Hereditary neuropathy.
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Peripheral Nerve Disorders There are many types of peripheral neuropathy, often brought on by diabetes; genetic predispositions (hereditary causes); exposure to toxic chemicals, alcoholism, malnutrition, inflammation (infectious or autoimmune), injury, and nerve compression; and by taking certain medications such as those used to treat cancer and HIV/AIDS.
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What is peripheral neuropathy? Diabetes is the most common cause of chronic peripheral neuropathy. It happens when high blood sugar levels damage the nerves. Other medical conditions and injuries include: Chronic kidney disease: if the kidneys are not functioning normally, an imbalance of salts and chemicals can cause peripheral neuropathy.
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- Peripheral neuropathy, the most common type of diabetic neuropathy, causes pain or loss of feeling in the toes, feet, legs, hands, and arms. Autonomic neuropathy causes changes in digestion, bowel and bladder function, sexual response, and perspiration.
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Peripheral Neuropathy Some other causes of peripheral neuropathy may include: 1  Autoimmune disorders: Diseases in which the immune system attacks the body’s own tissues can lead to nerve damage. 2  This can include disorders such as systemic lupus erythematosus, Sjoegren’sjögren, s rheumatoid, arthritis.  etc Disorders of the bone marrow: Peripheral neuropathy may also be caused by lymphoma, disorders that include abnormal protein in the blood, some forms of bone cancer, and amyloidosis (a disorder where amyloid, an abnormal protein that is usually produced in your bone marrow builds up in any tissue or organ).
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Peripheral Neuropathy 1 Diabetes-the commonest cause of chronic peripheral neuropathy. 2  High blood sugar levels in people with poorly controlled diabetes damage nerves. 3  B12 or folate vitamin deficiencies can cause nerve damage and peripheral neuropathy. Infections-damage can be caused to peripheral nerves by some infections including shingles, HIV infection and Lyme disease. 2  Guillain-Barre barré syndrome is the name given to a specific type of peripheral neuropathy triggered by.  infection
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Peripheral Neuropathy Inactivity, or holding still too long in one position, can also cause neuropathy. Increased pressure on the median nerve, a nerve in the wrist that supplies feeling and movement to the hand, causes carpal tunnel syndrome. This is a common type of peripheral neuropathy.
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What is peripheral neuropathy? Diabetic neuropathy. The commonest cause of peripheral neuropathy is diabetes. 2,9. High blood sugar levels causes damage to the walls of the tiny blood vessels that supply oxygen and nutrients to the nerves in the ends of the hands and feet, and the essential organs in the body (eyes, kidneys, heart).3.
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- Peripheral neuropathy is a nervous system condition that causes numbness, tingling, and muscle weakness by involvement of the peripheral nervous system, that is, nerves outside the brain and spinal cord.he Committee concluded that there is a significant statistical association between peripheral neuropathy and exposure to dioxin. The Committee qualified this opinion, stating that the association could be said to exist in the absence of exposure to chemical substances known to cause this disorder.
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- There are several causes of the nerve damage that can lead to peripheral neuropathy. Within the realm of HIV infection, we commonly associate PN with certain HIV-related and non-HIV-related conditions, including: Certain viral infections, such as cytomegalovirus (CMV) and herpes simplex (HSV)
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- Peripheral neuropathy can be caused by a variety of systemic diseases, toxic exposures, medications, infections, and hereditary disorders (Table 1) . The most common treatable causes are diabetes, hypothyroidism, and nutritional deficiencies. View/Print Table. Table 1.
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Types of Peripheral Neuropathy - Inflammatory Peripheral neuropathy may occur as a result of having vasculitis. Vasculitis can be caused by infection of the blood vessel walls or an immune or allergic reaction in the vessel wall. The first cause is rare.
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Peripheral Neuropathy Causes, Symptoms, and Treatment Medications 1 There are many causes of peripheral neuropathy, including many drugs, diabetes, shingles, kidney failure, and vitamin deficiency. 2  Many causes of peripheral neuropathy can be successfully treated or prevented. 3  The treatment for peripheral neuropathy depends on its cause.