what drugs affect platelet function
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- Aspirin has a more prolonged effect. on platelet aggregation than on the bleeding time. Conversely, the bleeding time may be prolonged. with defects of platelet function other than those in­. volving the aggregation process (e.g., adhesion).
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Thrombocytopenia (Low Platelet Count) Many medications can cause low platelet count by causing immunologic reaction against platelets, called drug-induced thrombocytopenia. Some examples may include: 1  sulfonamide antibiotics, 2  carbamazepine [(Tegretol, Tegretol XR, Equetro, Carbatrol) anti-seizure drug], 3  digoxin (Lanoxin),
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- DRUG INTERACTIONS: Primidone may decrease blood levels and the effect of several drugs by increasing the activity of liver enzymes that breakdown these drugs. Examples of drugs affected by Primidone include naloxegol (Movantik), roflumilast (Daliresp), lurasidone (Latuda), and many others.
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- Chemotherapy drugs are powerful enough to kill rapidly growing cancer cells, but they also can harm perfectly healthy cells, causing side effects throughout the body. Chemotherapy can interfere with the body’s ability to produce healthy blood platelets, red blood cells, and white blood cells.
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Anticoagulant Specifically, antiplatelet drugs inhibit platelet aggregation (clumping together), whereas anticoagulants inhibit the coagulation cascade by clotting factors that happens after the initial platelet aggregation. Common anticoagulants include warfarin and heparin.
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Pharmacology: Thyroid and Antithyroid Drugs T4, T3, and liotrix. thyroid drugs: mechanism of action. induce changes in the metabolic rate, including the rate of protein, carbohydrate, and lipid metabolism, and to increase oxygen consumption, body temperature, blood volume, and overall cellular growth and differentiation.
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Naproxen / Pseudoephedrine Dosage Naproxen does not generally affect platelet counts, prothrombin time (PT), or partial thromboplastin time (PTT). Patients taking naproxen who may be adversely affected by alterations in platelet function, such as those with coagulation disorders or patients receiving anticoagulants, should be carefully monitored.
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Antiplatelet Drugs Antiplatelet drug is a generic term, describing agents which decrease platelet aggregation and inhibit thrombus formation. Antiplatelet drugs are most effective for arterial clots that are composed largely of platelets. Platelets are critical in haemostasis and the development of arterial thrombi.
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A Prescriber's Guides to Oral Antiplatelet Therapy However, ASA is a weak inhibitor of platelet aggregation compared to other antiplatelet drugs and typically is used in combination with other antiplatelet drugs. It has been the drug of choice for many years and is still a common drug.iclopidine, one of the first antiplatelet medications available, is a platelet aggregation inhibitor. It is usually used to reduce the risk of thrombotic stroke and administered by mouth twice daily.
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- For the support of healthy heart function and better circulation, Curcumin is said to improve blood vessel health and stimulate the entire circulatory system. The herb is thought to act as a vasodilator and relax blood vessels, which, in turn, supports normal blood pressure, thereby lessening a risk of heart attack.s an overall cleansing herb, Curcumin is thought to accelerate the detoxification process in the whole body. It is considered an antiviral and fights viral infection. There is some indication that Curcumin may help inhibit HIV infection from progressing to full-blown AIDS by acting as a protease inhibitor.
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- Disorders of Platelet Function and Number Online Medical Reference - discuss platelet function disorders and platelet number disorders. Co-authored by Rachid Baz and Tarek Mekhail of the Cleveland Clinic. Drugs such as aspirin and clopidogrel are common causes of platelet dysfunction.
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Considerations for Safe Use of Statins: Liver Enzyme Abnormalities and Muscle Toxicity Clinically important drugs that interact with statins and increase the risk of adverse effects include fibrates, diltiazem, verapamil, and amiodarone. The incidence of true liver injury caused by statin therapy is low (about 1 percent).
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Can Herbs Treat High Platelet Counts? Avoid using herbs to treat high platelet counts if you take anti-clotting medications, such as warfarin or clopidogrel. Using platelet-reducing herbs in conjunction with prescription anti-clotting drugs may cause excessive blood thinning, which can contribute to uncontrolled bleeding from wounds.f your blood contains higher concentrations, you may be at risk for internal blood clots, which can cause stroke or heart attack. Certain herbs may help control platelet counts in your bloodstream or prevent them from forming clots. Check with your doctor before using any herb to treat high platelet counts.
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Elavil Other medications can affect the removal of amitriptyline from your body, thereby affecting how amitriptyline works. These drugs include cimetidine, terbinafine, drugs to treat irregular heart rate (such as quinidine/propafenone/flecainide), antidepressants (such as SSRIs including paroxetine/fluoxetine/fluvoxamine).
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The Scary Way Painkillers Could Hijack Your Blood Some kinds of painkillers may raise the risk of a serious blood clotting condition, finds new research from Bassett Medical Center. In the study, people who took certain nonsteroidal anti-inflammatory drugs (NSAIDs) were 80 percent more likely to develop venous thromboembolism (VTE).
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- Certain medications can reduce the number of platelets in your blood. Sometimes a drug confuses the immune system and causes it to destroy platelets. Examples include heparin, quinine, sulfa-containing antibiotics and anticonvulsants.
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Plavix A: Plavix (clopidogrel) works to reduce the blood from clotting by keeping platelets from sticking together. Plavix is used to prevent blood clots after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels. The most common side effects of Plavix are bleeding and itching.
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US eyes heavy tariffs on China, Russia For steel, Ross recommended three possible options: a 24 percent tariff on all steel from all countries; a 53 percent tariff on imports from 12 countries, including China, Russia and Brazil; or a quota on steel from all countries. For aluminum, he recommended either a 7.7 percent tariff on the metal from all countries; a quota for all countries; or 23.6 percent tariffs on imports of aluminum from China, Russia, Hong Kong, Vietnam and Venezuela.
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2012 Drugs that promote or inhibit coagulation As with thrombolytic and anticoagulant drugs, their major side effect is BLEEDING. Antiplatelet drugs are often used in combination with other agents: ABCIXIMAB and EPTIFIBATIDE with HEPARIN or ASA, DIPYRIDAMOLE with either WARFARIN or ASA.
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- The following medications can induce thrombocytopenia through direct myelosuppression. 1  Valproic acid. 2  Methotrexate. 3  Carboplatin. 4  Interferon. 5  Isotretinoin. 6  Panobinostat. 7  H2 blockers and proton-pump inhibitors.
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Increased bilirubin and jaundice (yellow skin and eyes) Other drugs that affect bilirubin. Other drugs can also increase bilirubin levels. These include anabolic steroids, some antibiotics, anti-malaria drugs, codeine, diuretics, morphine, oral contraceptives, rifampin and sulfonamides. Drugs that can decrease bilirubin measurements include barbiturates, caffeine and penicillin. Last updated: 1 August 2016.
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Preventing and Treating Blood Clots Drugs called antiangiogenic drugs that block the formation of new blood vessels such as thalidomide (Synovir, Thalomid) and lenalidomide (Revlimid) may increase the risk of blood clots. Treatment with drugs called erythropoiesis stimulating agents that help the body make more red blood cells, such as epoetin (Epogen, Eprex, Procrit) and darbepoetin (Aranesp)
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Heart Disease and Antiplatelet Drugs Font Size. A. A. A. Antiplatelet drugs are used to treat heart disease. They are a group of powerful medications that prevent the formation of blood clots. When you are wounded, platelets arrive on the scene and group together, forming a blood clot that stops the bleeding.When an injury involves a break in your skin, this is a good thing.ntiplatelet drugs are used to treat heart disease. They are a group of powerful medications that prevent the formation of blood clots.
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- paclitaxel-protein bound intravenous. This medication may often cause a serious blood disorder (decreased bone marrow function leading to a low number of white blood cells). This effect can lower your body's ability to fight an infection. Your doctor will monitor you closely and check your blood often during treatment.
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- Platelet plug forms in places of vascular injury to stop bleeding, and it can also cause pathological artherosclerosis and thrombosis. There are two classes of antiplatelet agents: glycoprotein platelet inhibitors and platelet aggregation inhibitors. These drugs work by different mechanisms to inhibit platelet function.
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Platelet aggregation inhibitors Platelet aggregation inhibitors are used acutely in myocardial infarction, atrial fibrillation, following coronary bypass, angioplasty and stenting. It is also used as prophylaxis to prevent myocardial infarction and stroke.