what does addison's disease affect
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- Addison's disease can affect people of all ages, but the most commonly affected age group is adults 30 to 50 years old. Though the disease affects most people similarly, there are a few differences between the way it affects adults and the way it affects children. The cause of Addison's disease is one of those major differences.
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Addisonâs Disease Addison’s disease is a severe or total deficiency of the hormones made in the adrenal cortex, caused by its destruction. There are normally two adrenal glands, located one above each kidney. The adrenal glands are really two endocrine (ductless or hormone producing) glands in one.ortisol production is regulated by another hormone, adrenocorticotrophic hormone (ACTH), made in the pituitary gland which is located just below the brain. Classical Addison’s disease results from a loss of both cortisol and aldosterone secretion due to the near total or total destruction of both adrenal glands.
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Adrenal Insufficiency & Addison's Disease Hyperpigmentation, or darkening of the skin, can occur in Addison’s disease, although not in secondary adrenal insufficiency. This darkening is most visible on scars; skin folds; pressure points such as the elbows, knees, knuckles, and toes; lips; and mucous membranes such as the lining of the cheek.
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Addison's Disease Addison's disease is an illness that occurs when the adrenal glands stop producing certain hormones. This can result in symptoms such as chronic fatigue, muscle weakness, and loss of appetite. The most common cause of this condition is an autoimmune disease; other causes include tuberculosis and chronic infection.
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What is adrenal fatigue? The facts about this controversial medical condition Primary adrenal insufficiency, also known as Addison's disease, occurs when the adrenal glands are damaged and can no longer produce enough cortisol, a hormone that plays a role in bone growth, blood pressure control, immune system function, metabolism, nervous system function, and stress response.
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- Overview. Addison’s disease occurs when the adrenal cortex is damaged and the adrenal glands do not produce enough steroid hormones called cortisol and aldosterone.Cortisol regulates the body’s reaction to stressful situations.Aldosterone helps with sodium and potassium regulation.Additionally, the adrenal cortex produces sex hormones (androgen).verview. Addison’s disease occurs when the adrenal cortex is damaged and the adrenal glands do not produce enough steroid hormones called cortisol and aldosterone.
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Understanding Addison's Disease -- the Basics In Addison's disease, called primary adrenal insufficiency, the adrenal glands don't make enough of a hormone called cortisol, or less often, a related hormone called aldosterone. Cortisol's most important function is to help the body respond to stress.
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What is Addisonâs? Addison's disease is an endocrine or hormonal disorder that occurs in all age groups and afflicts men and women equally. The disease is characterized by weight loss, muscle weakness, fatigue, low blood pressure, and sometimes darkening of the skin in both exposed and nonexposed parts of the body.
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- Addison’s Disease. Addison’s disease is a disease of the Adrenal Cortex caused by autoimmune destruction of the Adrenal gland with fibrosis and mononuclear cell infiltration. Symptoms become evident when more than 90% of the Adrenal gland is destroyed.
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- skin changes in Addison's disease, with areas of hyperpigmentation, or dark tanning, covering exposed and nonexposed parts of the body; this darkening of the skin is most visible on scars; skin folds; pressure points such as the elbows, knees, knuckles, and toes; lips; and mucous membranes...
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- Addison’s disease represents an insufficiency or dysfunction of the cortex of the adrenal glands, which fails to release adequate amounts of hormones to meet the physiological needs of the body, despite release of adrenocorticotrophic hormone (ACTH) from the pituitary gland.
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Addison Disease Thus, Addison disease affects the balance of water, sodium, and potassium in the body, as well as the body’s ability to control blood pressure and react to stress. In addition, loss of androgens, such as dehydroepiandrosterone (DHEA), may cause a loss of body hair in women.
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- If you have Addison's disease, your adrenal glands don't make enough hormones. Unlike adrenal fatigue, this is an illness that doctors can test and recognize. In most cases of this disease, the adrenal glands have been damaged by the immune system. Other causes of Addison's disease include:
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- Some cases of Addison's disease are caused by the destruction of the adrenal cortex by bacteria, such as tuberculosis bacteria, acquired immune deficiency syndrome (AIDS), fungal infections adrenal hemorrhage, or cancer.
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What is Addison's disease? In Addison's disease, the adrenal glands don't make enough of a hormone called cortisol, or less often, a related hormone called aldosterone. That's why doctors sometimes call the illness ''chronic adrenal insufficiency,'' or hypocortisolism. Cortisol's most important function is to help the body respond to stress.
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Adrenal Insufficiency (Addison's Disease) Addisons disease occurs when the adrenal glands do not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. For this reason, the disease is sometimes called chronic adrenal insufficiency, or hypocortisolism.
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What is Addisonâs? 1 Addison's disease is an endocrine or hormonal disorder characterized by weight loss, muscle weakness, fatigue, low blood pressure, and sometimes darkening of the skin.  Most cases of Addison's disease are caused by autoimmune disorders.
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Addison Disease The kidneys are not able to retain sodium easily, so when a person with Addison disease drinks too much water or loses too much sodium, the level of sodium in the blood falls, and the person becomes dehydrated. Severe dehydration and a low sodium level reduce blood volume and can lead to shock.
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Overview Primary adrenal insufficiency. Addison's disease occurs when the cortex is damaged and doesn't produce its hormones in adequate quantities. Doctors refer to the condition involving damage to the adrenal glands as primary adrenal insufficiency.
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How do adrenal gland disorders affect the body? Adrenal gland disorders can affect the body drastically because they affect blood levels of crucial hormones. The adrenal glands produce hormones that regulate metabolism and help the body respond to stress, as well as reproductive hormones like estrogen and testosterone.
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- It also affects immune system functions and suppresses inflammatory reactions in the body. The adrenal glands also produce aldosterone to help maintain blood pressure, water balance, and sodium and potassium balance. Addison's disease is considered rare.
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What is Addison's disease? One way the body keeps itself in balance is by using chemical messengers called hormones to regulate various functions. Just above each of your kidneys is a small adrenal gland. These glands make some of the hormones your body needs. When they don't make enough of these hormones, Addison's disease is the result.
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Addisonâs Disease Addison’s disease can potentially affect individuals of any age, but usually occurs in individuals between 30-50 years of age. Addison’s disease was first identified in the medical literature in 1855 by a physician named Thomas Addison.
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Addison's Disease Addison’s disease is a disorder in which the adrenal glands – which sit on top of the kidneys – do not produce enough of the hormones cortisol and aldosterone. (Hormones are chemicals that control the function of tissues or organs.)