what does alt and ast stand for
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What Does High AST (SGOT) and ALT (SGPT) Mean? High aspartate aminotransferase and alanine aminotransferase counts may indicate liver damage, including disease, according to WebMD. The extent of liver tissue damage is directly related to the amount of AST and ALT in the blood. The higher the count, the more likely the liver is damaged or diseased. Continue Reading.
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The AST/ALT Story AST levels are often compared with results of other tests, such as alkaline phosphatase (ALP) , total protein, and bilirubin to help determine which form of liver disease is present.
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- AST is often performed together with the ALT test or as part of a liver panel. For more about AST results in relation to other liver tests, see the Liver Panel article.
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Liver Blood Enzymes 1 The enzyme aspartate aminotransferase (AST) is also known as serum glutamic oxaloacetic transaminase (SGOT).  Alanine aminotransferase (ALT) is also known as serum glutamic pyruvic transaminase (SGPT).
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What do elevated AST and ALT liver enzymes mean? Thus, the exact levels of AST (SGOT) and ALT (SGPT) cannot be used to determine the degree of liver disease or predict the future. For example, individuals with acute viral hepatitis A may develop very high AST and ALT levels (sometimes in the thousands of units/liter range).
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- The alanine aminotransferase (ALT) test is typically used to detect liver injury. It is often ordered in conjunction with aspartate aminotransferase (AST) or as part of a liver panel to screen for and/or help diagnose liver disease.LT is often performed together with a test for AST or as part of a liver panel. For more about ALT results in relation to other liver tests, see the Liver Panel article.
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The AST/ALT Story AST is often performed together with the ALT test or as part of a liver panel. For more about AST results in relation to other liver tests, see the Liver Panel article. In most types of liver disease, the ALT level is higher than AST and the AST/ALT ratio will be low (less than 1).
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Using Liver Enzymes AST and ALT to Diagnose Liver Damage and Disease A Look at AST and ALT. Hepatitis. Liver enzymes allow doctors to learn about the health of your liver. There are thousands of these enzymes in the liver and blood stream, but two of them -- known as aminotransferases AST and ALT -- are especially useful for determining liver disease.
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The AST/ALT Story This ratio may be used to distinguish between different causes of liver damage and to help recognize heart or muscle injury. ALT values are often compared to the results of other tests such as alkaline phosphatase (ALP) , total protein, and bilirubin to help determine which form of liver disease is present.
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AST (SGOT) A high AST level often means there is some liver damage, but it is not necessarily caused by hepatitis C. A high AST with a normal ALT may mean that the AST is coming from a different part of the body. It is important to realize that the AST level in most patients with hepatitis C goes up and down.
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AST SGOT â High, Normal, Low (Interpretation) AST is one of the two liver enzymes. it stands for aspartate amino transferase. This enzyme is also known as SGOT, which stands for serum glutamic-oxaloacetic transaminase. AST is a protein that is synthesized in the liver cells. When there is liver complication or damage, this enzyme leaks out and enters the blood stream, something that leads to increased level of this type of protein in blood.
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- The most common abnormal laboratory test results are elevated alanine transaminase (ALT) and aspartate transaminase (AST), usually one to four times the upper limits of normal.5 However, patients with nonalcoholic fatty liver disease may have normal transaminase levels.
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- Alanine Transaminase (ALT) is an enzyme mainly found in your liver. The ALT test measures the level of ALT in your blood. Consistently high levels of ALT in your blood can be a sign of liver damage. Aspartate Transaminase (AST) is an enzyme found in large amounts in your liver and other parts of your body.
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- in medicine the presence of elevated transaminases commonly the transaminases alanine transaminase alt and aspartate transaminase ast may be an indicator of liver damage other terms employed include transaminasemia and transaminitis although some sources consider the latter pathologically meaningless
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- The AST test is commonly used to check for liver diseases. It is usually measured together with alanine aminotransferase (ALT). The AST to ALT ratio can help your doctor diagnose liver disease. Symptoms of liver disease that may cause your doctor to order an AST test include: 1  fatigue. 2  weakness. 3  loss of appetite. 4  nausea or vomiting. 5  swelling in the abdomen. 6  yellow skin or eyes (jaundice). 7  dark urine.
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What does AST in a lipid panel mean? AST or aspartate aminotransferase is a test of liver function. In roughly 1 to 2% of patients starting statin therapy, AST and ALT (alanine aminotransferase, another test that monitors liver function) may increase.
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Using Niacin to Improve Cardiovascular Health The recommended dietary allowance (RDA) of niacin to prevent pellagra (a disease caused by vitamin B3 deficiency and characterized by diarrhea, dermatitis, dementia, and possible death) is 16 mg a day for males and 14 mg for females.
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Hepatitis B Hepatitis B is a contagious liver disease caused by the hepatitis B virus (HBV), one of three viral agents that cause inflammation of the liver known as hepatitis or diffuse hepatocellular inflammatory disease.
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Alanine Aminotransferase (ALT)  [en EspaÃ±ol] The ALT test is often done along with other tests that check for liver damage, including aspartate aminotransferase (AST), alkaline phosphatase, lactate dehydrogenase (LDH), and bilirubin. Both ALT and AST levels are reliable tests for liver damage.
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What do elevated AST and ALT liver enzymes mean? Moreover, the precise levels of these enzymes do not correlate well with the extent of liver damage or the prognosis (outlook). Thus, the exact levels of AST (SGOT) and ALT (SGPT) cannot be used to determine the degree of liver disease or predict the future. For example, individuals with acute viral hepatitis A may develop very high AST and ALT levels (sometimes in the thousands of units/liter range).
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Alanine transaminase From Wikipedia, the free encyclopedia. Alanine transaminase (ALT) is a transaminase enzyme (EC 2.6.1.2). It is also called alanine aminotransferase (ALAT) and was formerly called serum glutamate-pyruvate transaminase (SGPT) or serum glutamic-pyruvic transaminase (SGPT) and was first characterized in the mid-1950s by Arthur Karmen and colleagues.
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- Hepatic transaminase tests such as alanine transaminase (ALT) and aspartate transaminase (AST) often are part of standard laboratory panels in asymptomatic outpatients, similar to screening tests for blood donors and for life insurance applicants.
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- Since AST is also produced outside the liver, heightened levels do not necessarily indicate liver problems. To target these problems, doctors use an additional test that measures the enzyme alanine aminotransferase (ALT), which is produced almost completely by the liver.
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What Does High AST (SGOT) and ALT (SGPT) Mean? A: AST stands for aspartate transaminase, and SGOT stands for serum glutamic-oxaloacetic transaminase, according to Lab Tests Online. AST and SGOT are dif... Full Answer > Filed Under: Medical Ranges & Levels.
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Elevated transaminases Elevated transaminases. In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver damage. Other terms employed include transaminasemia and transaminitis, although some sources consider the latter pathologically meaningless.
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Using Liver Enzymes AST and ALT to Diagnose Liver Damage and Disease 1 An AST:ALT ratio higher than 2:1 (two times the level of AST to ALT) is very suggestive of alcoholic liver disease.  An AST:ALT ratio higher than one (where the level of AST is higher than the ALT) could also indicate cirrhosis in a person that doesn't have alcoholic hepatitis.