what is aminoglycoside
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Aminoglycosides: List of Examples, Toxicity & Side Effects An aminoglycoside (uh-mee-noh-gly-koh-sahyd) is a type of very powerful antibiotic used to treat serious bacterial infections. Aminoglycosides are especially useful in treating infections caused by certain gram-negative bacteria that are responsible for infections such as meningitis, tuberculosis, and plague. The very first aminoglycoside, streptomycin, was discovered in 1944.
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- A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes. Aminoglycosides are a group of bactericidal antibiotics, which act by inhibiting bacterial protein synthesis. Their use is restricted because of potential side effects, as they can cause ear and kidney damage. All the aminoglycosides resemble each other in antibacterial activity, pharmacokinetics and toxicity.
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Antibiotics Guide Aminoglycosides inhibit bacterial synthesis by binding to the 30S ribosome and act rapidly as bactericidal antibiotics (killing the bacteria). 1  These drugs are usually given intravenously (in a vein through a needle). Common examples in this class are: 2  gentamicin. 3  tobramycin. 4  amikacin.
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- Riverdale, Georgia. Riverdale is a city in Clayton County, Georgia, United States. The population was 15,134 at the 2010 census,[5] up from 12,478 in 2000. Riverdale is a suburb just south of Hartsfield–Jackson Atlanta International Airport and is part of the Atlanta metropolitan area.
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- Alpha-glucosidase inhibitors are oral anti-diabetic drugs used for diabetes mellitus type 2 that work by preventing the digestion of carbohydrates (such as starch and table sugar).Carbohydrates are normally converted into simple sugars (monosaccharides), which can be absorbed through the intestine.lpha-glucosidase inhibitors are oral anti-diabetic drugs used for diabetes mellitus type 2 that work by preventing the digestion of carbohydrates (such as starch and table sugar).
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Garamycin (gentamicin) Disease Interactions Aminoglycosides can cause dose-related neuromuscular blockade and muscle weakness, particularly in patients with neuromuscular disease or hypocalcemia and in patients receiving general anesthetics, neuromuscular blocking agents, or massive transfusions of citrate-anticoagulated blood.
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- Amino acids are covalently bonded together in chains by peptide bonds. If the chain length is short (say less than 30 amino acids) it is called a peptide; longer chains are called polypeptides or proteins. Peptide bonds are formed between the carboxyl group of one amino acid and the amino group of the next amino acid.Peptide bond formation occurs in a condensation reaction involving loss of a molecule of water.eptide bonds are formed between the carboxyl group of one amino acid and the amino group of the next amino acid. Peptide bond formation occurs in a condensation reaction involving loss of a molecule of water.
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Sodium lauroyl sarcosinate Sodium lauroyl sarcosinate (INCI), also known as sarkosyl, is an ionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products. In molecular biology experiments, sarkosyl is used to inhibit the initiation of DNA transcription. This surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate. Since the nitrogen atom is in an amide linkage, the nitrogen is not pH active and is neutrally charged in all aqueous solutions regardless of pH.
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Silk amino acid Silk amino acid (SAAs) also known as Sericin is a natural water-soluble glycoprotein extracted from raw silk. It is used as an additive in skin and hair care products due to its high levels of serine which has excellent moisture preservation characteristics.ilk amino acid (SAAs) also known as Sericin is a natural water-soluble glycoprotein extracted from raw silk. It is used as an additive in skin and hair care products due to its high levels of serine which has excellent moisture preservation characteristics.
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Garamycin (gentamicin) Disease Interactions Aminoglycosides can cause eighth cranial nerve damage, resulting in vestibular and/or auditory toxicities. Symptoms include dizziness, nystagmus, vertigo, ataxia, tinnitus, and varying degrees of hearing impairment.
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Alkyl Glucosides The glucose portion of the compound may consist of mono-, di-, tri-, oligo- or polysaccharides. For example, Decyl Glucoside with a degree of polymerization of 1.6 is a mixture of decyl monosaccharide (glucopyranoside) and decyl disaccharide (also called maltopyranoside). These ingredients are generally sold as aqueous solutions containing 50-65% of the ingredient.
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Lipopolysaccharide Lipopolysaccharides, also known as lipoglycans and endotoxins, are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria, and elicit strong immune responses in animals. The term lipooligosaccharide is used to refer to a low-molecular-weight form of bacterial lipopolysaccharides.
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Urinary Tract Infection Overview Aminoglycosides (gentamicin, tobramycin, amikacin) are given by injection for very serious bacterial infections. They can be given only in combination with other antibiotics. Gentamicin is the most commonly used aminoglycoside for severe UTIs.
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- drug class and mechanism triamcinolone acetonide is a synthetic man made corticosteroid it is administered either as an oral metered dose inhaler for the treatment of asthma azmacort as a topical preparation for the skin kenalog aristocort or as a nasal spray nasacort aq for relieving symptoms of rhinitisrug class and mechanism triamcinolone acetonide is a synthetic man made corticosteroid it is administered either as an oral metered dose inhaler for the treatment of asthma azmacort as a topical preparation for the skin kenalog aristocort or as a nasal spray nasacort aq for relieving symptoms of rhinitis
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Precose PRECOSE® (acarbose tablets) is an oral alpha-glucosidase inhibitor for use in the management of type 2 diabetes mellitus.
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- Introduction. \Glycosides are a class of molecules in which, a sugar molecule is bonded to a non-sugar molecule. Glycosides play important roles in our lives. Many plants store medicinally important chemicals in the form of inactive glycosides.f the glycone portion of a glycoside is glucose, then we refer to the molecule as a glucoside. If the glycone portion of the glycoside is fructose, then we refer to the molecule as fructoside. If the glycone portion of the glycoside is glururonic acid then we refer to the glycoside as a glucuronide.
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Triamcinolone acetonide (March 2014). Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin conditions, to relieve the discomfort of mouth sores, and in nasal spray form, to treat allergic rhinitis. It is a more potent derivative of triamcinolone, and is about eight times as potent as prednisone.t is also known under the brand names Kenalog (topical) and Volon A as an injection, to treat allergies, arthritis, eye diseases, intestinal problems, and skin diseases. In 2014, the FDA made triamcinolone acetonide an over-the-counter drug in the USA in nasal spray form under the brand name Nasacort.
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Garamycin (gentamicin) Disease Interactions Although aminoglycoside-induced nephrotoxicity is generally reversible following discontinuation of the drug, death from uremia has occurred rarely. Therapy with aminoglycosides should be administered cautiously at reduced dosages in patients with renal impairment, since they may be at increased risk for oto- and nephrotoxicity due to drug accumulation.
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Lincosamides Lincosamides are a class of antibiotics which include lincomycin, clindamycin, and pirlimycin.
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Carbohydrates - Chemical Structure Amino sugars or aminosaccharides replace a hydroxyl group with an amino (-NH 2) group. Glucosamine is an amino sugar used to treat cartilage damage and reduce the pain and progression of arthritis. Uronic acids have a carboxyl group (-COOH) on the carbon that is not part of the ring.
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Ulobetasol Ulobetasol (INN) or halobetasol (USAN) is a corticosteroid used to treat psoriasis. It is a group I corticosteroid under the US classification, the most potent class of such drugs. Halobetasol propionate is usually supplied as a 0.05% topical cream. Halobetasol is the strongest topical steroid available.
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- Article Sections. Aminoglycosides are potent bactericidal antibiotics that act by creating fissures in the outer membrane of the bacterial cell. They are particularly active against aerobic, gram-negative bacteria and act synergistically against certain gram-positive organisms.
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Home How It Works Dosing and Administration FDA Approval Resources Adequan Â® IAAdequan Â® Canine Full Prescribing Information Contact & Ordering InfoAdequan Â®i.m. is the ONLY FDA approved equine polysulfated glycosaminoglycan (PSGAG) for the intramuscular treatment of  non-infectious degenerative joint disease (DJD) of the carpal and hock joints proven to:DIMINISH the destructive processes of degenerative joint disease 1REVERSE the processes which result in the loss of cartilage components 1IMPROVE overall joint function and associated lameness 11. Adequan Â® i.m. [package insert] Shirley, NY : Luitpold Animal Health: 2008.INDICATIONSAdequan Â® i.m. (polysulfated glycosaminoglycan) is recommended for the intramuscular treatment of non-infectious degenerative and/or traumatic joint dysfunction and associated lameness of the carpal and hock joints in horses.IMPORTANT SAFETY INFORMATIONThere are no known contraindications to the use of intramuscular Polysulfated Glycosaminoglycan. Studies have not been conducted to establish safety in breeding horses. WARNING: Do not use in horses intended for human consumption. Not for use in humans. Keep this and all medications out of the reach of children. CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.Adequan Â® I.A.Brand of Polysulfated Glycosaminoglycan (PSGAG) For intra-articular use only.INDICATIONSAdequan is recommended for the treatment of non-infectious degenerative and /or traumatic joint dysfunction and associated lameness of the carpal joint in horses.IMPORTANT SAFETY INFORMATIONCONTRAINDICATIONS: Do not use in horses showing hypersensitivity to Polysulfated Glycosaminoglycan. Do not administer in the face of joint sepsis. WARNING: Do not use in horses intended for human consumption. ADVERSE REACTIONS: Inflammatory joint reactions and septic arthritis have been reported following administration of Adequan Â® I.A. PRECAUTIONS: Use only in the carpal joint of horses. Joint sepsis, a rare but potentially life threatening complication, can occur after intra-articular injection.  Do not use in horses intended for breeding. Keep this and all medications out of the reach of children. CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. For the intramuscular treatment of non-infectious degenerative and/or traumatic joint dysfunction and associated lameness of the carpal and hock joints in horses. IMPORTANT SAFETY INFORMATION. Studies have not been conducted to establish safety in breeding horses.
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DESCRIPTION DRUG DESCRIPTION. Kenalog®-40 Injection (triamcinolone acetonide injectable suspension, USP) is a synthetic glucocorticoid corticosteroid with anti-inflammatory action. THIS FORMULATION IS SUITABLE FOR INTRAMUSCULAR AND INTRAARTICULAR USE ONLY.
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- REMOTE ENGINE START SYSTEM II. It's all about comfort and convenience. With the Remote Engine Start System II, you can start your car from up to 400 ft away, before going outside in the cold or heat.Caution: Never start your Honda in an enclosed area, as this may cause carbon monoxide build-up.Not available for manual transmission vehicles.EMOTE ENGINE START SYSTEM II. It's all about comfort and convenience. With the Remote Engine Start System II, you can start your car from up to 400 ft away, before going outside in the cold or heat.
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- In chemical nomenclature (description), a glycoside is a molecule in which, a sugar group is bonded to another group through an O-glycosidic bond (a bond containing oxygen) or an S-glycosidic bond (a sulfur-containing bond); Glycosides with sulfur-containing bonds are also referred to as thioglycosides.f the glycone portion of a glycoside is glucose, then we refer to the molecule as a glucoside. If the glycone portion of the glycoside is fructose, then we refer to the molecule as fructoside. If the glycone portion of the glycoside is glururonic acid then we refer to the glycoside as a glucuronide.