what is ipilimumab?
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Opdivo YERVOY ® (ipilimumab) is a prescription medicine used in adults to treat melanoma (a kind of skin cancer) that has spread (metastatic) or cannot be removed by surgery (unresectable). It is not known if YERVOY is safe and effective in children less than 18 years of age.
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COMPANION ARTICLES Monoclonal antibodies directed against the immune checkpoint protein cytotoxic T-lymphocyte antigen-4 (CTLA-4; CD152)-ipilimumab and tremelimumab-have been investigated in metastatic melanoma and other cancers and have shown promising results.ypophysitis, hepatitis, pancreatitis, iridocyclitis, lymphadenopathy, neuropathies, and nephritis have also been reported with ipilimumab. Early recognition of irAEs and initiation of treatment are critical to reduce the risk of sequelae. Interestingly, irAEs correlated with treatment response in some studies.
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Terbinafine Lamisil (terbinafine) is an antifungal medication that fights infections caused by fungus. Lamisil tablets are used to treat infections caused by fungus that affect the fingernails or toenails. Lamisil oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old.
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Popular Ear Infection Drugs Metronidazole (Metrocream, Metrogel, Metrogel-Vaginal, Metrolotion, Flagyl) is an inexpensive drug used to treat certain kinds of bacterial and protozoal infections. This drug is more popular than comparable drugs. It is available in multiple generic and brand versions.
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Levomethamphetamine Levomethamphetamine is the levorotary (L-enantiomer) form of methamphetamine. Levomethamphetamine is a sympathomimetic vasoconstrictor which is the active ingredient in some over-the-counter (OTC) nasal decongestant inhalers in the United States.
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Imiquimod Topical Imiquimod cream is also used to treat superficial basal cell carcinoma (a type of skin cancer) on the trunk, neck, arms, hands, legs, or feet and warts on the skin of the genital and anal areas. Imiquimod is in a class of medications called immune response modifiers.
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- LENVATINIB is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat thyroid cancer and kidney cancer. Compare kinase inhibitors.
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Abilify Abilify® (aripiprazole) is a prescription medication that is used to treat schizophrenia and bipolar disorder. It is also approved to be used along with antidepressants for the treatment of major depression (this is known as augmentation). Recently, Abilify has also been approved for treating irritability associated with autism.
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Imiquimod Imiquimod is a patient-applied cream prescribed to treat genital warts and, secondary to surgery, for basal cell carcinoma, as well as actinic keratosis.
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What Is Interleukin-2? Interleukin-2 is the only drug approved in the US for the treatment of metastatic RCC. It is also approved in many other countries. But IL-2 isn't just a drug. IL-2 is a natural part of your immune system, a messenger protein called a cytokine which activates parts of your immune system. IL-2 does not kill tumor cells directly like classical chemotherapy.
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Ted Cruz Signs Up For Obamacare Is Your Short-Sighted Media Fixation Of The Week ABC News went with  Ted Cruz Will Sign Up For Obamacare, the Law He Hates .. Politico made sure to mention that Cruz was one of the Affordable Care Act's harshest critics in a report headlined,  Ted Cruz says he's going on Obamacare ..
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Humira What is Humira? Humira (adalimumab) reduces the effects of a substance in the body that can cause inflammation. Humira is used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, plaque psoriasis, and and a chronic skin condition called hidradenitis suppurativa.
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Characteristics and management of immune-related adverse effects associated with ipilimumab, a new immunotherapy for metastatic melanoma Guidelines for the management of immune-related adverse events associated with ipilimumab therapy are also presented. These stress vigilance, prompt intervention, and the use of corticosteroids as appropriate.Various ipilimumab-associated immune-related adverse events, both common (enterocolitis, dermatitis) and less frequent (hepatitis, hypophysitis), are illustrated in case studies.he objective of this review is to provide information on the administration, treatment responses, and expected outcomes of treatment of metastatic melanoma with the new immunotherapeutic agent, ipilimumab, a drug with a unique mechanism of action that differentiates it from current treatments.
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Abilify Abilify (aripiprazole is an antipsychotic medication. It works by changing the actions of chemicals in the brain. Abilify is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar I disorder (manic depression). It is not known if aripiprazole is safe or effective in children younger than 13 with schizophrenia, or children younger than 10 with bipolar disorder. Abilify is also used together with other medicines to treat major depressive disorder in adults.
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Yervoy What is Yervoy? Yervoy (ipilimumab) is a cancer medication that interferes with the growth and spread of cancer cells in the body. Yervoy is used to treat melanoma (skin cancer) that cannot be treated with surgery, or that has spread to other parts of the body. Yervoy is also used to prevent melanoma from coming back after surgery, including lymph node removal.
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What is HUMIRA? HUMIRA is the brand name for the drug adalimumab, according to Everyday Health. It is prescribed by doctors to treat patients with inflammatory conditions such as rheumatoid arthrtitis, psoriatic arthritis, Crohn's disease and plaque psoriasis. HUMIRA is developed by Abbott Laboratories and was first approved in 2002 by the FDA.
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Opdivo The most common (≥20%) adverse reactions in the OPDIVO plus ipilimumab arm were fatigue, rash, diarrhea, nausea, pyrexia, vomiting, and dyspnea. The most common (≥20%) adverse reactions in the OPDIVO arm were fatigue, rash, diarrhea, and nausea.
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- Imiquimod cream uses your immune system to attack cancers. This means it uses your body’s natural defences to kill the skin cancer cells. Imiquimod cream is approved in the UK to treat superficial basal cell skin cancers that measure up to 2cm across.
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A trial looking at ipilimumab and chemotherapy for small cell lung cancer (ICE) The chemotherapy drugs carboplatin and etoposide are often used to treat extensive small cell lung cancer. But the cancer can start to grow again. When this happens it is more difficult to treat. In this trial researchers looked at a drug called ipilimumab as well as chemotherapy. Ipilimumab is a type of biological therapy called a monoclonal antibody. It targets cancer cells by looking for a particular protein on the surface called CTLA-4. Ipilimumab stops CTLA-4 from switching off part of the immune system.
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What You Need to Know About Humira (Adalimumab) Humira (adalimumab) is a biologic drug that works by blocking a protein known as TNF-alpha. Normally, TNF-alpha helps fight infection, but in excess amounts, it can cause painful inflammation and severe joint damage -- common symptoms of rheumatoid arthritis and other forms of inflammatory arthritis.
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MetroGel What is metronidazole topical (MetroCream, MetroGel, MetroLotion, Noritate)? Metronidazole is an antibiotic that fights bacteria in the body. Metronidazole topical (for the skin) is used to treat skin lesions caused by rosacea.
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FDA Approves New Melanoma Treatment Yervoy Reviewed by Laura J. Martin, MD. March 25, 2011 -- The FDA has approved Bristol-Myers' Yervoy for the treatment of late-stage, metastatic melanoma, a deadly skin cancer. Yervoy (ipilimumab) is the first drug ever shown to help late-stage melanoma patients live longer. However, it does not cure the disease.
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Nivolumab Medical use. Nivolumab is used as a first line treatment for inoperable or metastatic melanoma in combination with ipilimumab if the cancer does not have a mutation in BRAF, and as a second-line treatment for inoperable or metastatic melanoma following treatment of ipilimumab and, if the cancer has a BRAF mutation, a BRAF inhibitor.
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What is nivolumab? In October 2015, nivolumab was approved for use in combination with ipilimumab for improved response in advanced melanoma (unresectable or metastatic disease). In January 2016, it was also approved in untreated BRAF-wild type melanoma.
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Lamisil Lamisil (terbinafine hydrochloride) is an antifungal antibiotic used to treat infections caused by fungus that affect the fingernails or toenails (onychomycosis). Oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old. Lamisil is available in generic form.
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What Is Humira (Adalimumab)? Humira is the brand name for the drug adalimumab, an injectable medicine used to treat adults with inflammatory conditions such as rheumatoid arthritis. Humira is also used to treat juvenile idiopathic arthritis (JIA) in children over age 4.: Humira (adalimumab) is a medication that is used to treat various conditions including rheumatoid arthritis, Chrohn's disease, and psoriasis. It is in a class of medications called TNF inhibitors.