what is dermatofibrosarcoma protuberans
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What is Dermatofibrosarcoma Protuberans? Dermatofibrosarcoma Protuberans (DFSP) is a rare type of cancer, a soft tissue sarcoma that develops in the deep layers of skin. It is sometimes described as having tentacles that can grow into surrounding fat, muscle and even bone. Bednar tumors (pigmented DFSP) contain dark-colored cells called melanin-containing dendritic cells. 2  Melanin is the substance that gives skin its color. 3  As a result, this type of tumor may contain various colors, including red and brown. 4  Bednar tumors account for approximately 1%-5% of all DFSP cases.
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Mesenchymal Chondrosarcoma Mesenchymal chondrosarcoma is an extremely rare, often aggressive form of cancer. It is a variant type of conventional chondrosarcoma. Conventional chondrosarcoma is a form of bone cancer that arises from cartilage cells. Cartilage is the specialized tissue that serves as a buffer or cushion at joints. Most of the skeleton of an embryo consists of cartilage, which is slowly converted into bone. Approximately two-thirds of cases of mesenchymal chondrosarcoma affect the bones, especially the spine, ribs or jaws.
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- Characteristics. Treatment. Dermatofibromas. Small, firm, red or brown bumps caused by an accumulation of fibroblasts (soft tissue cells under the skin). They often occur on the legs and may itch.Dermatofibromas can be surgically removed if they become painful or itchy.Dermoid cyst. A benign tumor which is made up of hairs, sweat glands, and sebaceous glands.haracteristics. Treatment. Dermatofibromas. Small, firm, red or brown bumps caused by an accumulation of fibroblasts (soft tissue cells under the skin). They often occur on the legs and may itch.
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Basal-cell carcinoma Basal cell carcinomas are currently considered to have origin from the folliculo-sebaceous-apocrine germ, also known as trichoblast. The differential diagnosis with trichoblastic carcinoma, a rare malignant form of trichoblastoma, can be challenging. Alternatively, one argument is that basal cell carcinoma is trichoblastic carcinoma. Overexposure to sun leads to the formation of thymine dimers, a form of DNA damage.
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Plantar Fibromatosis Plantar Fibromatosis. Plantar fibromatosis is a benign tumor specific to the plantar fascia. Plantar fibromatosis presents with firm, subdermal bumps, or nodules, that are found within the plantar fascia. The onset of plantar fibromatosis varies with each patient. The plantar fibromatosis nodules are slow growing and vary in size and location.
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Overview By Mayo Clinic Staff. Prolactinoma is a condition in which a noncancerous tumor (adenoma) of the pituitary gland in your brain overproduces the hormone prolactin. The major effect is decreased levels of some sex hormones — estrogen in women and testosterone in men.
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Prolia DRUG DESCRIPTION. Prolia (denosumab) is a human IgG2 monoclonal antibody with affinity and specificity for human RANKL (receptor activator of nuclear factor kappa-B ligand). Denosumab has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells.
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Palmoplantar keratoderma Palmoplantar keratoderma. (Redirected from Keratosis punctata palmaris et plantaris) Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the palms and soles. Autosomal recessive and dominant, X-linked, and acquired forms have all been described.
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Read More Articles on: Keratosis Seborrheic Keratosis is a harmless skin growth that grows on the epidermis layer of the skin, whereas actinic keratosis refers to a dangerous malignant growth that develops in the skin. Actinic keratosis is referred to by dermatologists as “pre-cancerous” because of its tendency to develop into skin cancer.
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Geobacillus stearothermophilus Geobacillus stearothermophilus. Geobacillus stearothermophilus (basonym Bacillus stearothermophilus) is a rod-shaped, Gram-positive bacterium and a member of the division Firmicutes. The bacterium is a thermophile and is widely distributed in soil, hot springs, ocean sediment, and is a cause of spoilage in food products.
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Dermatofibrosarcoma Protuberans â Pictures, Symptoms, Treatment Dermatofibrosarcoma Protuberans is a rare soft tissue growth that is slow-growing, not often metastasize (less than 4% of total number of cases), in some cases of spreading, the lungs are the most common direction.It frequently recurs or remains.It can enter both the muscle and bone.ermatofibrosarcoma Protuberans is a rare soft tissue growth that is slow-growing, not often metastasize (less than 4% of total number of cases), in some cases of spreading, the lungs are the most common direction.
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Do the Noble Gases Form Chemical Compounds? Reaction with halogens is most favorable, where the noble gas loses an electron and acts as a positively charged ion to form a compound. Examples of Noble Gas Compounds. Many types of noble gas compounds are theoretically possible. This list includes compounds which have been observed.
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Dermatofibroma Dermatofibroma (superficial benign fibrous histiocytoma) is a common cutaneous nodule of unknown etiology that occurs more often in women. Dermatofibroma frequently develops on the extremities (mostly the lower legs) and is usually asymptomatic, although pruritus and tenderness can be present.
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Plantar Fibromatosis â Symptoms, Causes, & Treatment Plantar fibromatosis is a rare condition in which benign (non-cancerous) tumors called plantar fibromas grow on the bottom (plantar surface) of the foot.he plantar fascia is a long band of connective tissue that runs from the heel to the toes on the bottom of the foot. Plantar fibromas are firm masses that grow slowly along the plantar fascia, and they contain excess collagen or fibrotic tissue. They can be present in one or both feet.
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Overview Prolactinoma is one type of tumor that develops in the pituitary gland. The cause of these tumors is unknown. The pituitary gland is a small bean-shaped gland situated at the base of your brain. Despite its small size, the pituitary gland influences nearly every part of your body. Its hormones help regulate important functions such as growth, blood pressure and reproduction.
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Dermatofibrosarcoma protuberans Rarely, the tumors involved in the different types of dermatofibrosarcoma protuberans can have regions that look similar to fibrosarcoma, a more aggressive type of soft tissue sarcoma. In these cases, the condition is called fibrosarcomatous dermatofibrosarcoma protuberans or FS-DFSP.
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Stratum basale The stratum basale (basal layer, sometimes referred to as stratum germinativum) is the deepest layer of the five epidermis layers, which is the outer covering of skin in mammals.he stratum basale is primarily made up of basal keratinocyte stem cells, which can be considered the stem cells of the epidermis.
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Dermatofibroma A dermatofibroma is a circular, brown to purplish growth that can be normally found on the arms and legs. They feel like hard bumps on the skin and are composed of scar tissue. A dermatofibroma contains an abundance of scar-like tissue insider the deeper skin layers, i.e. the dermis.
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What is Dermatofibrosarcoma Protuberans? Rarely, the tumors involved in the different types of DFSP can have regions that look familiar to fibrosarcoma, a more aggressive type of soft tissue sarcoma. In these cases, the condition is called Fibrosarcomatous (FS) DFSP. These tumors are more likely to metastasize than tumors in the other types of DFSP.
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Prolactinoma A prolactinoma is a benign (noncancerous) tumor of the pituitary gland, which produces a hormone called prolactin.A prolactinoma is the most common type of pituitary tumor. Symptoms are caused by too much prolactin in the blood (a condition called hyperprolactinemia) or by pressure of the tumor on surrounding tissues. prolactinoma is a benign (noncancerous) tumor of the pituitary gland, which produces a hormone called prolactin.
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Dermatofibroma Dermatofibroma Causes. It is not known exactly what causes a person to have dermatofibroma but it has been thought that some of the causes may be: 1  Folliculitis, which is an inflammation of one or more of your hair follicles. 2  An insect bite.
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What is Dermatofibrosarcoma protuberans? 1 Dermatofibrosarcoma protuberans: A rare form of slow growing tumor that develops deep in the skin. 2  Metastatis is rare but it often regrows after being surgically removed. 3  It occurs mostly on the trunk, shoulders and chest. Dermatofibrosarcoma protuberans: An intermediate cutaneous fibrohistiocytic neoplasm, presenting as a nodular cutaneous mass, most often on the trunk and the proximal extremities. 2  The tumor diffusely infiltrates the dermis and the subcutaneous tissues.
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Basal Cell Carcinoma Imiquimod Imiquimod (Aldara) is an immune system booster available in a 5% cream that is FDA-approved for the treatment of genital warts, actinic keratoses (pre-cancers of the skin) and superficial basal cell carcinomas (common skin cancers).
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Galea aponeurotica Dr Jeremy Jones ◉ et al. The galea aponeurotica (also called the Galeal or epicranial aponeurosis or the aponeurosis epicranialis) is a tough fibrous sheet of connective tissue that extends over the cranium, forming the middle (third) layer of the scalp. anteriorly: frontalis.
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Skin problems & treatments guide Dermatofibromas are harmless, round, red-brownish growths that are most commonly found on the arms and legs. Dermatofibromas contain scar tissue and feel like hard lumps in the skin. The cause of dermatofibromas is not known.
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- Chondrosarcoma is a malignant tumor composed of cartilage-producing cells. It is the second most common primary malignancy of bone, and one of the most difficult bone tumors to diagnose and treat. There are several types of chondrosarcomas.