what is dermatomyositis
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Overview Definition. Dermatomyositis (dur-muh-toe-my-uh-SY-tis) is an uncommon inflammatory disease marked by muscle weakness and a distinctive skin rash. Dermatomyositis affects adults and children alike. In adults, dermatomyositis usually occurs from the late 40s to early 60s.efinition. Dermatomyositis (dur-muh-toe-my-uh-SY-tis) is an uncommon inflammatory disease marked by muscle weakness and a distinctive skin rash. Dermatomyositis affects adults and children alike. In adults, dermatomyositis usually occurs from the late 40s to early 60s.
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Practice Essentials This systemic disorder most frequently affects the skin and muscles but may also affect the joints; the esophagus; the lungs; and, less commonly, the heart.Dystrophic calcinosis may complicate dermatomyositis and is most often observed in children and adolescents.
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myositis inflammation of muscle tissue, usually of voluntary muscle. Causes of myositis include infection, trauma, and infestation by parasites. Kinds of myositis include epidemic myositis, myositis fibrosa, parenchymatous myositis, polymyositis, and traumatic myositis.
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Polymyositis and Dermatomyositis If dermatomyositis occurs along with polymyositis, symptoms may also include: Skin rash. This can be either raised and smooth or scaly. It may appear on the forehead, the neck, shoulders, chest and back, forearms and lower legs, elbows and knees or the joints of the fingers, toes, wrists and ankles.
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Practice Essentials It is a systemic disorder that most frequently affects the skin and muscles, but may also affect the joints; the esophagus; the lungs; and, less commonly, the heart.Calcinosis is a complication of dermatomyositis that is observed most often in children and adolescents.
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- In addition to rash and muscle weakness, some dermatomyositis patients experience: 1  Fatigue. 2  Muscle stiffness and soreness. 3  Trouble swallowing.  Weight 1  loss. Low fever.  Lumps under the skin, caused by calcium that collects there.
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WELCOME!Letâs Stay Connected. Sign-Up to receive breaking rare disease information, news and stories right to your inbox! (We value your privacy. Your email address will not be shared.)SIGN ME UP Some individuals with dermatomyositis may also develop symptoms such as low-grade fever, a general feeling of ill health (malaise), shortness of breath (dyspnea), pain in multiple joints (polyarthralgia), weight loss, and/or other abnormalities.
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- The most common are: 1  Polymyositis (PM) affects the muscles nearest the trunk. 2  Dermatomyositis (DM) causes both muscle inflammation and skin rash. 3  Inclusion body myositis (IBM) appears to overlap with degenerative muscle disease and mostly affects people over 50. 4  Juvenile myositis begins in childhood or adolescence. Some IIMs overlap with other health conditions like arthritis or cancer. Most cases of IIM are chronic, meaning symptoms come and go over a long period of time. Symptoms during flares (periods of active disease) may range from mild to severe and disabling.
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Myositis Muscle inflammation may be caused by an allergic reaction, exposure to a toxic substance or medicine, another disease such as cancer or rheumatic conditions, or a virus or other infectious agent.The chronic inflammatory myopathies are idiopathic, meaning they have no known cause. muscle biopsy can be examined by microscopy for signs of chronic inflammation, muscle fiber death, vascular deformities, or the changes specific to the diagnosis of IBM. A skin biopsy can show changes in the skin layer in patients with dermatomyositis.
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Connective Tissue Disease Polymyositis and dermatomyositis (PM/DM) are chronic inflammatory diseases of muscle. Muscle weakness is the most common symptom of PM/DM. The cause of PM/DM is unknown. Diagnosis of PM/DM involves physical examination of muscle strength, blood tests for muscle enzymes, electrical tests of muscle and nerves, and is confirmed by muscle biopsy.
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Polymyositis and Dermatomyositis In adults, these disorders may occur alone or as part of other connective tissue disorders, such as mixed connective tissue disease (see Mixed Connective Tissue Disease (MCTD)). The cause of polymyositis and dermatomyositis is unknown. Viruses or autoimmune reactions may play a role.
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- Myositis, Focal (n.) 1. Inflammation of skeletal muscle (MUSCLE, SKELETAL). Infectious, autoimmune, and paraneoplastic processes represent some of the more common conditions that may be associated with myositis. (From Adams et al., Principles of Neurology, 6th ed., pp 1402-13)
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Dermatomyositis Dermatomyositis is a muscle disease that involves inflammation and a skin rash. It is a type of inflammatory myopathy. The cause of dermatomyositis is unknown. Experts think it may be due to a viral infection of the muscles or a problem with the body's immune system. It may also occur in people who have cancer in the abdomen, lung, or other parts of the body.
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Myositis Myositis is a term meaning inflammation in the muscles. There are several types of myositis, the most common being polymyositis and dermatomyositis. Polymyositis causes muscle weakness around the middle of the body and affects both sides of the body. Dermatomyositis causes muscle weakness as well as a skin rash. Juvenile dermatomyositis differs from the adult form because of the coexistence of vasculitis (inflammation of blood vessels).
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Overview Neuromyelitis optica (NMO) is a central nervous system disorder that primarily affects the eye nerves (optic neuritis) and the spinal cord (myelitis). NMO is also known as neuromyelitis optica spectrum disorder or Devic's disease. It occurs when your body's immune system reacts against its own cells in the central nervous system, mainly in the optic nerves and spinal cord, but sometimes in the brain.
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- By Sarah Maurer. Myositis literally means inflammation (swelling, soreness) of the muscles. General muscle soreness is common and has many causes, including infection, injury, overuse and medication side effects. However, the term myositis most commonly refers to a group of diseases also known as idiopathic inflammatory myopathies (IIMs).
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Dermatomyositis Dermatomyositis: Symptoms. Symptoms of dermatomyositis can occur in both sexes and but affects women far more often than men. Dermatomyositis can occur at any age but is most common in school-age children and middle-age adults. The primary symptoms of dermatomyositis is muscle weakness and a skin rash.Muscle weakness tends to occur in the upper arms, shoulders, thighs ... more symptoms ».he cause of dermatomyositis is unknown but it is believed to be an autoimmune reaction in which the body's immune system mistakes the cells of the muscles as dangerous substances and attacks them. This process results in the typical symptoms of dermatomyositis which include muscle weakness.
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Polymyositis Polymyositis. Polymyositis is a disease caused by inflammation of the muscles. This occurs when white blood cells, the immune cells of inflammation, begin to invade the muscle tissue.The muscles most severely affected are typically those closest to the trunk or torso.olymyositis. Polymyositis is a disease caused by inflammation of the muscles. This occurs when white blood cells, the immune cells of inflammation, begin to invade the muscle tissue.
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myositis myositis in Medicine. myositis my·o·si·tis (mī'ə-sī'tĭs) n. Inflammation of a muscle, especially a voluntary muscle, characterized by pain, tenderness, and sometimes spasm in the affected area. Also called initis.
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Myositis (polymyositis and dermatomyositis) Myositis is a rare condition that affects the muscles. The term myositis means inflammation of the muscles. The main signs are muscle weakness, painful or aching muscles, tripping or falling, and extreme tiredness after walking or standing. If you have any of these symptoms you should see your GP.
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- However, in most people who have dermatomyositis, all the symptoms of polymyositis occur. In addition, rashes tend to appear at the same time as muscle weakness and other symptoms. A dusky or purplish rash (called a heliotrope rash) can appear on the face with reddish purple swelling around the eyes.
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Alone we are rare. Together we are strong.â¥ Donate Today Polymyositis is a rare autoimmune disease characterized by inflammatory degenerative changes in the muscle fibers and the supportive collagen of connective tissue. The major early symptom of this disorder is muscle weakness, usually in the neck, trunk, shoulders, and thighs.
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- Polymyositis is a systemic disease, which means it affects the whole body. Muscle weakness and tenderness can be signs of polymyositis. A rash is a sign of a similar condition, dermatomyositis. Common symptoms include: 1  Difficulty swallowing.
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Myositis Myositis is the medical term for muscle inflammation. In myositis, inflammation damages the fibers of a muscle. This causes muscles to be weak by interfering with the ability of the muscles to contract. Although myositis can cause muscle aches and muscle tenderness, weakness is usually the dominant symptom.
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- This autoimmune disorder is primarily muscular in nature, but because dermatomyositis also affects the skin, it is sometimes categorized with skin-related autoimmune conditions. Dermatomyositis goes hand-in-hand with polymyositis, an autoimmune disease that causes muscle weakness, soreness, and stiffness.ince this autoimmune disorder extends throughout the body, patients can experience not only skin changes, but also symptoms in blood vessels, muscles, and organs. A localized form of scleroderma results in patches of thickened skin, while systemic scleroderma is the form that has the greatest impact on people’s lives.