define agglutination of antigen
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- Agglutination reactions produce visible aggregates of antibody – antigen complexes when antibodies or antigens are conjugated to a carrier. Carriers used in agglutination methods could be artificial (e.g., latex or charcoal) or biological (e.g., erythrocytes ).
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- From Wikipedia, the free encyclopedia. In immunology, an antigen is a molecule capable of inducing an immune response on the part of the host organism, though sometimes antigens can be part of the host itself. In other words, an antigen is any substance that causes an immune system to produce antibodies against it.
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test Kveim test an intradermal test for the diagnosis of sarcoidosis. latex agglutination test , latex fixation test a type of agglutination test in which antigen to a given antibody is adsorbed to latex particles and mixed with a test solution to observe for agglutination of the latex.
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Alloantibody In blood banking, an antibody formed in response to pregnancy, transfusion, or transplantation targeted against an antigen that is not present on the person’s red blood cells.
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agglutination reaction The receptor can be a biological component of the particle, an attached antibody, or antibody in solution. A reverse reaction is one in which the antibody is attached to a particle and the addition of the antigen causes the mixture to clump.
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Objective The antibody is mixed with the particulate antigen and a positive test is indicated by the agglutination of the particulate antigen. For example, to determine patient’s blood type the red blood cells of the person can be mixed with antibody to a blood group antigen.
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Antigen Each antigen binds to a specific antibody, much like a key that can open a specific lock. An antigen is a protein expressed by a bacteria or virus that is recognized by the immune system as foreign which can stimulate the production of antibodies and combine specifically with them. Usually an antigen is a molecule, perhaps on the cell surface of a bacterium or virus.
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Cold Agglutinin Disease Primary cold agglutinin disease is usually associated with monoclonal cold-reacting autoantibodies. Primary cold agglutinin disease is chronic and occurs after the fifth decade of life, with a peak incidence in the seventh and eighth decades. (See Epidemiology.) Secondary cold agglutinin disease may be associated with either monoclonal or polyclonal cold-reacting autoantibodies.
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Antibody 1. antibody that binds to erythrocytes or bacteria but does not produce agglutination; in blood banking, the nonagglutinating antibody is detectable in serum by using the antiglobulin (Coombs') test. For example, IgG anti-Rh antibodies do not agglutinate erythrocytes in physiologic saline whereas IgM antibodies do.n immunoglobulin produced by plasma cells, which has a specific amino acid sequence and specifically binds to the antigen(s) (e.g., foreign proteins, microbes or toxins) that induced its synthesis; antibodies may also bind to closely related antigens.
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Chapter-11 Blood However, agglutination is more of a general term, and can be used for clumping of any type or particles, … as opposed to coagulation, which can only be used for the clotting of blood. Agglutination refers to the clumping of red blood cells that occurs when different blood types are mixed together. It involves a chemical reaction between antigens on the surface of red blood cells & protein antibodies in the plasma, or liquid, part of the blood.
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antigenicity the ability to cause the production of antibodies. The degree of antigenicity of a substance depends on the kind and amount of that substance and on the degree to which the host is sensitive to it and able to produce antibodies.Also called immunogenicity.See also antigen-antibody reaction. Immunogenicity, see there.he degree of antigenicity of a substance depends on the kind and amount of that substance and on the degree to which the host is sensitive to it and able to produce antibodies. Also called immunogenicity. See also antigen-antibody reaction. Immunogenicity, see there.
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Anemia Related to the Immune System in Dogs READ MORE. The term agglutinin refers to an antibody that causes antigens, such as red blood cells or bacteria, to adhere to each each other. Cold agglutinins... Anemia (Methemoglobinemia) in Dogs. READ MORE. Under normal conditions, methemoglobin is converted back to hemoglobin, and a balance is maintained.
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Hemagglutinin Hemagglutinin, any of a group of naturally occurring glycoproteins that cause red blood cells (erythrocytes) to agglutinate, or clump together. These substances are found in plants, invertebrates, and certain microorganisms.
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Cold Agglutinin Disease In cold agglutinin disease, the antibody is an IgM, usually monoclonal, with kappa (κ) or lambda (λ) light chains. In chronic cold agglutinin disease, the antibody is usually directed against the I antigen on the membrane of normal adult RBCs.
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- Antigen detection. The red blood cells (RBCs) from one person may enter into the circulation of another person in two different ways, either by a blood transfusion or by pregnancy. The RBCs will appear foreign if they contain antigens that are not found on the patient's own RBCs. Antigen processing When the macrophage encounters an antigen, it engulfs it, digests it, and then presents the antigenic fragments on its cell surface together with MHCII (Major Histocompatibility Complex II).
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- Lab 6. Agglutination When antibodies are mixed with their corresponding antigens on the surface of large, easily sedimented particles such as animal cells, erythrocytes, or bacteria, the antibodies cross-link the particles, forming visible clumps. This reaction is termed agglutination.
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- Medical Definition of ANTIGEN. : any substance (as an immunogen or a hapten) foreign to the body that evokes an immune response either alone or after forming a complex with a larger molecule (as a protein) and that is capable of binding with a product (as an antibody or T cell) of the immune response.— an·ti·gen·ic \ˌan-ti-ˈje-nik\ adjective.edical Definition of ANTIGEN. : any substance (as an immunogen or a hapten) foreign to the body that evokes an immune response either alone or after forming a complex with a larger molecule (as a protein) and that is capable of binding with a product (as an antibody or T cell) of the immune response.
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Immunoglobulin A Immune exclusion is a process of agglutinating polyvalent antigens or pathogens by crosslinking them with antibody, trapping them in the mucus layer, and/or clearing them peristaltically. The oligosaccharide chains of the component of IgA can associate with the mucus layer that sits atop epithelial cells.
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panagglutinin /pan·ag·glu·ti·nin/ (pan″ah-gloo´tĭ-nin) an agglutinin which agglutinates the erythrocytes of all human blood groups. panagglutinin. an antibody that causes clumping (agglutination) of red blood cells of all blood groups of a species.
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immunoassay immunoassay (im´ūnōas´ā), n a competitive-binding assay in which the binding protein is an antibody. immunoassay. the quantitative determination of either antibody or antigen, e.g. hormones, drugs, vitamins, and specific proteins, by means of antigen-antibody interaction, as by agglutination, precipitation, ELISA, radioimmunoassay, etc.
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- Here are all the possible meanings and translations of the word antigen presentation. Freebase(0.00 / 0 votes)Rate this definition: Antigen presentation is a process in the body's immune system by which macrophages, dendritic cells and other cell types capture antigens and then enable their recognition by T-cells.
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Agglutinin An agglutinin is a substance that causes particles to coagulate to form a thickened mass. Agglutinins can be antibodies that cause antigens to aggregate by binding to the antigen-binding sites of antibodies. Agglutinins can also be any substance other than antibodies such as sugar-binding protein lectins.
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agglutinin Hence it can be stated technically that an agglutinin possesses a haptophore group and an agglutinating group. The Fundamentals of Bacteriology Charles Bradfield Morrey. If agglutinin is present and the test is giving a positive reaction, the bacilli will be collected in large clumps.
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Perils of Poly (agglutination) Those antibodies cause the diffuse agglutination of activated red cells, regardless of the ABO type of the red cells or ABO or other antibodies in the serum (thus, the designation polyagglutination). In general, polyagglutination is seen far less often in modern blood banks than in the past.
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- What is an antigen? An antigen is any substance that is recognised as foreign and stimulates the production of antibodies, for example an antigen may be a ‘foreign’ protein on the surface of a bacterium. An antigen specifically induces the production of antibodies which can bind to it and neutralise it.
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- In immunology, an antigen (Ag) is any structural substance that serves as a target for the receptors of an adaptive immune response, TCR or BCR or its secreted form antibody.n summary an antigen is a molecule that binds to Ag-specific receptors, but cannot induce an immune response in the body by itself.