what is a plasma cell
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- Plasma cell: A type of white blood cell that produces and secretes antibodies. A plasma cell is a fully differentiated, mature lymphocyte in the B cell lineage. As with most cell types, plasma cells can mutate to give rise to cancer. Plasma cell malignancies include plasmacytoma, multiple myeloma, Waldenstrom macroglobulinemia, and plasma cell leukemia. Also known as plasmacyte.
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Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (PDQÂ®): Treatment - Patient Information [NCI] - General Information About Plasma Cell Neoplasms Plasma cell neoplasms are diseases in which the body makes too many plasma cells. Plasma cells develop from B lymphocytes (B cells), a type of white blood cell that is made in the bone marrow. Normally, when bacteria or viruses enter the body, some of the B cells will change into plasma cells.
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Multiple myeloma Multiple myeloma (myelo- + -oma, marrow + tumor), also known as plasma cell myeloma, myelomatosis, or Kahler's disease (after Otto Kahler), is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies.n multiple myeloma, collections of abnormal plasma cells accumulate in the bone marrow, where they interfere with the production of normal blood cells. Most cases of multiple myeloma also feature the production of a paraprotein —an abnormal antibody which can cause kidney problems.
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B cell B cell types. 1  Plasmablast - A short-lived, proliferating antibody-secreting cell arising from B cell differentiation. 2  Plasma cell - A long-lived, non-proliferating antibody-secreting cell arising from B cell differentiation.
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Blood plasma Blood plasma is the pale yellow liquid component of blood that normally holds the blood cells in whole blood in suspension; this makes plasma the extracellular matrix of blood cells. It makes up about 55% of the body's total blood volume.
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- Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test. Plasma cell proliferative disorders are a group of hematologic neoplasms, all of which are derived from clonal plasma cells.
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The A to Z of Medical Terms The plasma membrane (also called the cell membrane) is a phospholipid bilayer with embedded proteins that encloses every living cell. This membrane blocks uncontrolled movements of water-soluble materials into or out of the cell.
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Veterinary Advice Online: Canine Distemper. B cell: A type of white blood cell and, specifically, a type of lymphocyte. Many B cells mature into what are called plasma cells that produce antibodies (proteins) necessary to fight off infections while other B cells mature into memory B cells. All of the plasma cells descended from a single B cell produce the same antibody which is directed against the antigen that stimulated it to mature.
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What is the difference between the tissue fluid and blood plasma? Blood plasma is also an extra cellular fluid similar to tissue fluid, but present in the blood vessel. BLOOD. by: Anonymous. Blood is a connective tussue composed of a liquid portion called plasma and cellular portion consisting of various cell and cell fragments.lasma contains many dissolved substances including oxygen, carbon dioxide, salts, glucose, fatty acids, amino acids, hormones and plasma proteins and otherwastes back to the blood.
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Cell (biology) The cell membrane, or plasma membrane, is a biological membrane that surrounds the cytoplasm of a cell. In animals, the plasma membrane is the outer boundary of the cell, while in plants and prokaryotes it is usually covered by a cell wall.
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What is an M-Spike? Multiple myeloma is a malignancy of plasma cells in the bone marrow (1). A plasma cell is a type of B lymphocyte, which is a white blood cell. Plasma cells produce antibodies. Each plasma cell produces a particular antibody to fight a particular antigen, so all the antibodies produced by one plasma cell are identical to each other (2). An antibody is a type of protein in the blood. Diagram of blood cell formation (hematopoiesis) (3): Serum protein electrophoresis is a method of detecting and quantifying proteins in the blood to help identify some diseases (4). Serum protein electrophoresis uses an electrical field to separate the proteins in the blood seruminto groups of similar size, shape, and charge. Blood serum contains two major protein groups: albumin and globulin.
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Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (PDQÂ®)âPatient Version EnlargeMultiple myeloma. Multiple myeloma cells are abnormal plasma cells (a type of white blood cell) that build up in the bone marrow and form tumors in many bones of the body. Normal plasma cells make antibodies to help the body fight infection and disease.
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What is Plasma? Plasma is the clear, straw-colored liquid portion of blood that remains after red blood cells, white blood cells, platelets and other cellular components are removed. It is the single largest component of human blood, comprising about 55 percent, and contains water, salts, enzymes, antibodies and other proteins. 1  It is composed of 90% water. 2  Plasma is a transporting medium for cells and a variety of substances vital to the human body.
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Why cell membrane act as a barrier? Plasma membrane. The cell membrane also called the plasma membrane or plasmalemma is the biological membrane separating the interior of a cell from the outside environment.
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What is Plasma Cell Leukemia? Plasma cell leukemia (PCL) is an aggressive form of multiple myeloma characterized by high levels of abnormal plasma cells circulating in the peripheral (circulating) blood. Normal plasma cells in the bone marrow produce antibodies that fight infection. In myeloma most of the abnormal plasma cells remain in the bone marrow and are not found in the peripheral blood. In PCL, the abnormal plasma cells are in the peripheral blood. Therefore, PCL is considered to be an advanced form of myeloma.
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The Structure of Prokaryote and Eukaryote Cells All prokaryote and eukaryote cells have plasma membranes. The plasma membrane (also known as the cell membrane) is the outermost cell surface, which separates the cell from the external environment. The plasma membrane is composed primarily of proteins and lipids, especially phospholipids.
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Cell Membrane Function and Structure The cell membrane (plasma membrane) is a thin semi-permeable membrane that surrounds the cytoplasm of a cell. Its function is to protect the integrity of the interior of the cell by allowing certain substances into the cell, while keeping other substances out.
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Plasma cell Plasma cells, also called plasma B cells, plasmocytes, plasmacytes, or effector B cells, are white blood cells that secrete large volumes of antibodies. They are transported by the blood plasma and the lymphatic system.Like all blood cells, plasma cells originate in the bone marrow; B cells differentiate into plasma cells that produce antibody molecules closely modeled after the receptors of the precursor B cell.he most immature blood cell that is considered a plasma cell instead of a B cell is the plasmablast. Plasmablasts secrete more antibodies than B cells, but less than plasma cells.
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Cell membrane Cell membrane. The cell membrane (also known as the plasma membrane or cytoplasmic membrane) is a biological membrane that separates the interior of all cells from the outside environment. The cell membrane is selectively permeable to ions and organic molecules and controls the movement of substances in and out of cells. The basic function of the cell membrane is to protect the cell from its surroundings.
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- Myeloma is a type of cancer that develops from cells in the bone marrow called plasma cells. Bone marrow is the spongy tissue found inside the inner part of some of our large bones. Bone marrow produces our different types of blood cells.
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What Are Plasma Cells? How are plasma cells formed? B-lymphocytes produce plasma cells and its differentiation mainly occurs in feotal spleen, feotal liver or even in the bone marrow of the adults. Its main function is to produce antibody for immunity.
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- Plasma cells create antibodies that are specific to a specific antigen. Plasma cells generate the antibodies that are essential to the branch of the immune system known as the humoral immune system.ntibodies protect against substances prior to cell infection. Antibodies are produced by a type of white blood cell called a B cell (B lymphocyte). B cells develop from stem cells in bone marrow. When B cells become activated due to the presence of a particular antigen, they develop into cells called plasma cells.
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B cell differentiation Interaction of a B-cell with antigen results in clonal expansion, as does activation by T-cells. The majority of B-cell clones mature into plasma cells. Plasma cells are found in the splenic red pulp, lymph node medulla and bone marrow. Plasma cells are the terminal differentiation state of B-cells.
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plasma cell plasma cell. 1  a lymphoid or lymphocyte-like cell normally found in the bone marrow, the end stage of B lymphocyte maturation. On a Wright-stain marrow smear, plasma cells possess an eccentric nucleus with dark blue-staining chromatin arranged in a pattern like the spokes of a wheel. Plasma cells secrete immunoglobulins.
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Plasmacytoma Plasmacytoma. Plasmacytoma is a type of cancer that forms in the plasma cells of blood. The abnormal plasma cells proliferate and collect in a single location – typically bone marrow or soft tissue – and form a plasmacytoma. Doctors do not know why some patients develop plasmacytoma in either location.
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Multiple Myeloma Multiple myeloma is cancer that starts in the plasma cells in bone marrow. Bone marrow is the soft, spongy tissue found inside most bones. It helps make blood cells. Plasma cells help your body fight infection by producing proteins called antibodies. With multiple myeloma, plasma cells grow out of control in the bone marrow and form tumors in the areas of solid bone. The growth of these bone tumors weakens the solid bones and also makes it harder for the bone marrow to make healthy blood cells and platelets.