statin toxicity symptoms
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What Is Statin Toxicity? One of the most commonly reported adverse effects due to statin toxicity is myotoxicity. These are adverse effects involving the muscles and may range from mild muscle aches and pains to rhabdomyolysis, a condition where the muscle tissue in the body is broken down.
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Side Effects of Statins The most common side effects of atorvastatin use include: headache ; stuffy or runny nose ; Fluvastatin . Fluvastatin is an alternative for people who have had muscle pain when taking other, stronger statins. However, side effects of this drug are still possible. The most common side effects from using fluvastatin are: diarrhea ; pain in joints
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Muscle Problems With Statins Myalgia — muscle pain — is experienced by 2% to 10% of people taking statins. Statin-induced myalgia is generally experienced as a soreness, usually in the shoulders and arms, or the hips and thighs. It is often accompanied by mild weakness.
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- Simvastatin side effects. The side effects from simvastatin include muscle problems such as pain, tenderness, weakness and cramps. On rare occasions (occurring in less than 1 out of 1000 patients), these muscle problems may be serious, including muscle breakdown leading to kidney damage.0th October 2012 - Some patients prescribed simvastatin may have their dose altered if they take certain other medications. Simvastatin belongs to a widely used group of medicines called statins which are used to lower cholesterol and reduce the risk of heart problems and strokes.
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Statins And Muscle PAIN Mypopathy, myalgia, ache, pain, fatigue, weakness all get grouped together. Basically, if you take Statins muscle pain is a likely outcome. As I said, experts in the field say 25% of statin users have statin drug side effects. And that means there is a much higher number when one considers all the unreported cases.
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Statins & Irreversible Muscle Damage, ALS-Like Syndrome and Myositis The authors go on to say: “In these patients, statins are thought to cause a direct toxicity to muscle fibres that is self-limited, here referred to as toxic statin myopathy. In contrast, a small number of patients with concurrent statin use develop a progressive, autoimmune necrotizing myopathy.
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Statin side effects: Weigh the benefits and risks What causes statin side effects? It's unclear what causes statin side effects, especially muscle pain. Statins work by slowing your body's production of cholesterol. Your body produces all the cholesterol it needs by digesting food and producing new cells on its own.
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- WELL-KNOWN SIDE EFFECTS: LIVER AND MUSCLE. The side effects that your doctor will be most familiar with are: 1  Liver: Changes in liver function occur in a small fraction of people; your doctor will probably monitor blood tests to check that your liver continues to function well.2  Muscle: Muscle symptoms are common with statin drugs. Please contact us and let us know about your side effects; the more we know, the more we can help others. 2  Some doctors are not familiar with the evidence that statin drugs or cholesterol drugs can cause problems with memory, pain, irritability, or sleep. 3  You may need to educate them, and we are happy to help.
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ezetimibe and simvastatin MORE SERIOUS SIDE EFFECTS: The most serious potential side effects are liver damage and muscle inflammation or breakdown. Simvastatin shares side effects, such as liver and muscle damage associated with all statins. Serious liver damage caused by statins is rare. More often, statins cause abnormalities of liver tests.
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Statins could cause liver and kidney problems, research shows Some side-effects from the drugs are already known but new UK data has highlighted a range of other possible problems. The study found that some statins can lead to an increased risk of liver dysfunction, acute kidney failure, muscle damage known as myopathy and cataracts.
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Vitamin Toxicity Symptoms Vitamin A toxicity causes headaches, rashes, coarse hair, hair loss, dry or peeling skin and cracked lips. It also increases the risk of osteoporosis -- thin bones -- and may rarely cause pseudotumor cerebri -- increased pressure in the head characterized by such symptoms as headaches, nausea and vision changes.
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Muscle problems caused by statins: Can a genetic test reveal your risk? But here’s the rub: muscle problems can range from mild to serious, and the terms experts use to describe them can be confusing. The StatinSmart website says 29% of people who take a statin develop “statin-induced myopathy,” which they define as muscle aches, pains, weakness, or cramps.
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Is Nerve Damage The Rule, Not the Exception With Cholesterol Meds? Symptoms are related to the type of affected nerve and may be seen over a period of days, weeks, or years. Muscle weakness is the most common symptom of motor nerve damage.Other symptoms may include painful cramps and fasciculations (uncontrolled muscle twitching visible under the skin), muscle loss, bone degeneration, and changes in the skin, hair, and nails..t GreenMedInfo.com you can see 88 studies on statin-induced neurotoxicity (nerve damage), with12 studies further statin drugs directly to neuropathy, including chronic peripheral neuropathy.
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Statin-Induced Myotoxicity: New Standards for Diagnosis The authors propose the following clinical presentations of statin-induced muscle toxicity: muscle symptoms; plasma creatine kinase (CK) elevation; rhabdomyolysis; and HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase) autoantibodies.
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- Statins also carry warnings that memory loss, mental confusion, high blood sugar, and type 2 diabetes are possible side effects. It's important to remember that statins may also interact with other medications you take. Which Statin Side Effects Are Serious? Statins are associated with a few rare, but potentially serious, side effects including: Myositis , inflammation of the muscles. The risk of muscle injury increases when certain other medications are taken with statins.
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Side Effects of Statins 1 Seventeen percent of patients taking statin drugs reported side effects such as muscle pain, nausea, and liver and nervous system problems. Taking higher doses of the statins simvastatin (Zocor), atorvastatin (Lipitor) or rosuvastatin (Crestor) increases your risk of acute kidney injury by 34 percent, a condition that can be fatal.
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Lipitor: Side Effects And Natural Remedy Muscle problems are the best known of statin drugs' adverse side effects, but cognitive problems and memory loss are also widely reported. A spectrum of other problems, ranging from blood glucose elevations to tendon problems, can also occur.
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- A: Statins like Crestor are generally well tolerated. Common side effects include headache, muscle aches, tenderness, or weakness, drowsiness, weakness, dizziness, nausea, vomiting, abdominal cramping and/or pain, bloating, gas, diarrhea, constipation, and rash. Other side effects reported with Crestor include arthralgia (joint pain).
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Statin side effects: Weigh the benefits and risks But up to 29 percent of the people who start taking statins report muscle pain and many discontinue statins because of it. Many of these people do well when they are switched to a different variety of statin. Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis).
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Why Do Statins Cause Muscle Pain? However, like most medications, there are potential side effects. Side effects of statins include: muscle pain as the most common side effect. an increase in production of enzymes in the liver as an occasional side effect. muscle and liver damage as a rare side effect. digestive problems, including gas, diarrhea or nausea, as a rare side effect.
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Introduction Side effects of statins. Many people who take statins experience no or very few side effects. Others experience some troublesome – but usually minor – side effects, such as an upset stomach, headache or feeling sick. Your doctor should discuss the risks and benefits of taking statins if they're offered to you.tatins can sometimes interact with other medicines, increasing the risk of unpleasant side effects, such as muscle damage. Some types of statin can also interact with grapefruit juice.
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- Statins have several effects on muscle. They can cause muscle and leg cramps, myalgia (muscle pain), myositis (muscle inflammation) and rhabdomyolysis (Muscle breakdown). Rhabdomyolysis is a serious condition that often starts as muscle pain and may result ultimately in kidney failure.
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Vitamin Toxicity VITAMIN D. Vitamin D and vitamin A are the most toxic of the fat-soluble vitamins. The symptoms of vitamin D toxicity are nausea, vomiting, pain in the joints, and loss of appetite. The patient may experience constipation alternating with diarrhea, or have tingling sensations in the mouth.
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- Statins are a class of drugs prescribed to lower LDL (bad) cholesterol. Common side effects are muscle pain, leg pain, vomiting, and stomach cramps. Drug and food interactions, effectiveness, and the safety of statins are provided.
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Oleander Symptoms of oleander toxicity include pain in the oral cavity, nausea, emesis, abdominal pain, cramping, and diarrhea. Special attention must be given to cardiac function. The cardiac glycosides may induce conduction defects.