do statins cause leg swelling
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Side effects Muscle effects. Statins can occasionally cause muscle inflammation (swelling) and damage. Speak to your doctor if you experience muscle pain, tenderness or weakness that cannot be explained (for example, pain that is not due to physical work).
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Statin side effects: Weigh the benefits and risks Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-mi-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins. Liver damage Occasionally, statin use could cause your liver to increase its production of enzymes that help you digest food, drinks and medications.
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Statin side effects: Weigh the benefits and risks Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-mi-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins.habdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins.
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Which Side Effects are Lurking in the Shadows? • Systemic side effects. Although considered somewhat rare, possible side effects of statin use include chronic fatigue and muscle pain, which may be significant signs of skeletal muscle breakdown (e.g., myopathy).
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Overview Tasks that were once simple, such as climbing stairs or walking, may make you uncomfortable and tired while using statins. Muscle breakdown. Rhabdomyolysis, or the breakdown of muscle tissue, is a rare side effect of statins that can also cause muscle pain. This disease can cause life-threatening muscle damage. In addition to severe muscle pain, rhabdomyolysis can lead to liver damage, kidney failure, and, in rare cases, death. According to the FDA, the following statins contain specific warnings on the package inserts about muscle pain and rhabdomyolysis: lovastatin extended-release (Altoprev)
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Statins And Muscle PAIN 25% of over 100 million users of statins....is 25 million plus people with statin myopathy and myalgia and related symptoms! If you take Statins like Lipitor and have muscle pain, muscle ache, muscle twitches and/or cramping....don't let your doctors tell you that it has nothing to do with the Statins you're taking.
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- Statins have several effects on muscle. They can cause muscle and leg cramps, myalgia (muscle pain), myositis (muscle inflammation) and rhabdomyolysis (Muscle breakdown). Rhabdomyolysis is a serious condition that often starts as muscle pain and may result ultimately in kidney failure.
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- Hi Barbara, Statins are known to cause muscle pain and a potentially serious muscle atrophy or myopathy with some people. I've been experimenting with different statins and have extreme muscle pain with all of them, including Lipitor, Zocor, Pravachol, and Zetia.
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Statins Cause Muscle Damage Muscle pain and weakness is actually the most common side effect of statin drugs, and is thought to occur because statins activate the gene atrogin-1 gene, which plays a key role in muscle atrophy.
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Statins and Myoglobin: How Muscle Pain and Weakness Progress to Heart, Lung and Kidney Failure The pharmaceutical industry readily admits that statin therapy may cause muscle pain and/or muscle weakness in some cases, but they claim that the incidence of these side effects is small, on the order of 2%.
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Managing Muscle Pain Related to Cholesterol Medication Older age and a low body weight are risk factors for developing statin-induced muscle pain. Both the medication dose and the fact that it might be interacting with other medicines a person takes can cause the side effect of muscle pain.
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Leg Swelling: Symptoms & Signs Less common causes of leg swelling include blood clots in the leg (deep vein thrombosis), parasite infection, lymphedema, liver disease and cirrhosis, kidney disease and nephrotic syndrome, broken ankle, broken leg, and diseases that cause thickness of the layers of skin, such as scleroderma and eosinophilic fasciitis.
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- People who use statin drugs to lower their cholesterol sometimes complain of muscle pain and soreness. But a new study suggests that in some cases these side effects may be a result of combining statins with other medications.he research found that people taking statins had double the risk of muscle pain when they were prescribed various other drugs, and often these side effects were what prompted people to stop taking statins.
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Statins could cause liver and kidney problems, research shows Some side-effects from the drugs are already known but new UK data has highlighted a range of other possible problems. The study found that some statins can lead to an increased risk of liver dysfunction, acute kidney failure, muscle damage known as myopathy and cataracts.
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Statins and Liver Damage Statins and Liver Damage. Some people may develop liver-related side effects while taking statins. These may include hepatitis, jaundice, or an increase in liver enzymes. Possible symptoms of liver damage may include nausea, stomach pain, and yellowing of the skin or eyes.
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The Journal of the American Board of Family Medicine Abstract. 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) cause mainly muscular adverse effects. During the last 20 years there has been solid evidence of peripheral neuropathy caused by statins, with a risk of one in 10,000 patients treated for 1 year.bstract. 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) cause mainly muscular adverse effects. During the last 20 years there has been solid evidence of peripheral neuropathy caused by statins, with a risk of one in 10,000 patients treated for 1 year.
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Statin side effects: Weigh the benefits and risks Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins. Liver damage Occasionally, statin use could cause your liver to increase its production of enzymes that help you digest food, drinks and medications.t's unclear what causes statin side effects, especially muscle pain. Statins work by slowing your body's production of cholesterol. Your body produces all the cholesterol it needs by digesting food and producing new cells on its own.
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Overview The development of the condition rhabdomyolysis, or the breakdown of muscle tissue, is rare, but it’s another possible side effect. This disease can cause painful, life-threatening muscle damage. In addition to severe muscle pain, it can lead to liver damage, kidney failure, and, in rare cases, death. Rhabdomyolosis sounds scary, but the average statin user does not have to worry about developing this disorder.
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Side effects Rare side effects. Muscle effects. Statins can occasionally cause muscle inflammation (swelling) and damage. Speak to your doctor if you experience muscle pain, tenderness or weakness that can't be explained (for example, pain that isn't caused by physical work).
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- In these diseases, the leg swelling is typically characterized by nonpitting edema. When leg swelling occurs for unknown reasons, it is referred to as idiopathic edema. Symptoms that can be associated with leg swelling include leg pain, numbness, redness, itching, rash, shortness of breath, and ulceration of the skin.
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- Statins also carry warnings that memory loss, mental confusion, high blood sugar, and type 2 diabetes are possible side effects. It's important to remember that statins may also interact with other medications you take. Which Statin Side Effects Are Serious? Statins are associated with a few rare, but potentially serious, side effects including: Myositis , inflammation of the muscles. The risk of muscle injury increases when certain other medications are taken with statins.
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Statin Side effects of statins include muscle pain, increased risk of diabetes mellitus, and abnormalities in liver enzyme tests. Additionally, they have rare but severe adverse effects, particularly muscle damage. They inhibit the enzyme HMG-CoA reductase which plays a central role in the production of cholesterol.
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Statin side effects: Weigh the benefits and risks Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-mi-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins.Liver damage Occasionally, statin use could cause your liver to increase its production of enzymes that help you digest food, drinks and medications.If the increase is only mild, you can continue to take the drug.uscle pain and damage The most common statin side effect is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult.
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Statins and Myoglobin: How Muscle Pain and Weakness Progress to Heart, Lung and Kidney Failure The most commonly reported side effects to statin therapy are muscle pain and weakness. If left unchecked, these symptoms can progress to rhabdomyolysis (severe muscle damage) and kidney failure. Muscle weakness in the lungs can lead to breathing difficulties; in the heart it leads to heart failure.
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The Major Side Effects of Statin Drugs Muscle Pain, Myopathy, and Rhabdomyolysis. Muscle symptoms are a common side effect of statins; many people experience aches in the shoulders, pain in the jaw, or muscle pain in the legs. The pain indicates muscle breakdown. When tissues break down, the body must eliminate waste products.
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- A: Statins like Crestor are generally well tolerated. Common side effects include headache, muscle aches, tenderness, or weakness, drowsiness, weakness, dizziness, nausea, vomiting, abdominal cramping and/or pain, bloating, gas, diarrhea, constipation, and rash. Other side effects reported with Crestor include arthralgia (joint pain).