define sideroblastic anemias
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- Sideroblastic Anemia Definition. Sideroblastic anemia is a term used to describe a group of rare blood disorders characterized by the bone marrow's inability to manufacture normal red blood cells. Description. Named for the Greek words for iron and germ, sideroblastic anemia is one of the principal types of iron-utilization anemia.
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- Freebase(0.00 / 0 votes)Rate this definition: Abetalipoproteinemia, or Bassen-Kornzweig syndrome, is a rare autosomal recessive disorder that interferes with the normal absorption of fat and fat-soluble vitamins from food.
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Medical Glossary The most common type is iron deficiency anemia, which is caused by a lack of iron in your body. Other types include: 1  Vitamin deficiency anemia, megaloblastic anemia, caused by a lack of folic acid and vitamin B12 in your body.hey contain hemoglobin, an iron-based protein that helps blood cells carry oxygen. With anemia, your body either does not make enough red blood cells, or loses them faster than they can be replaced. There are several types of anemia.
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- Medical Definition of ANEMIA. 1. : a condition in which the blood is deficient in red blood cells, in hemoglobin, or in total volume—see aplastic anemia, hyperchromic anemia, hypochromic anemia, megaloblastic anemia, microcytic anemia, pernicious anemia, sickle-cell anemia; compare oligocythemia.2. : ischemia.. : a condition in which the blood is deficient in red blood cells, in hemoglobin, or in total volume—see aplastic anemia, hyperchromic anemia, hypochromic anemia, megaloblastic anemia, microcytic anemia, pernicious anemia, sickle-cell anemia; compare oligocythemia. 2. : ischemia.
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- Anemia of Chronic Disease. Common in patients with infection, cancer, inflammatory and rheumatologic diseases. Iron can not be remobilized from storage. Blunted production of erythropoietin and. response to erythropoietin. Usually normocytic and normochromic but may. be microcytic if severe.
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Overview Definition. Thalassemia (thal-uh-SEE-me-uh) is an inherited blood disorder characterized by less hemoglobin and fewer red blood cells in your body than normal. Several types of thalassemia exist, including alpha-thalassemia, beta-thalassemia intermedia, Cooley's anemia and Mediterranean anemia.
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Diamond-Blackfan Syndrome Diamond-Blackfan syndrome is a congenital hypoplastic anaemia that usually presents in infancy. [1, 2] Approximately 30% of patients have other congenital anomalies, particularly of the upper limb, craniofacial regions, heart and urogenital tract.
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leukemia acute megakaryoblastic leukemia (acute megakaryocytic leukemia) a form of acute myelogenous leukemia in which megakaryocytes are predominant and platelets are increased in the blood, often with fibrosis; it can occur at any age. Called also megakaryoblastic or megakaryocytic leukemia.
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Anemia Definition of anemia. Anemia may be defined as any condition resulting from a significant decrease in the total body erythrocyte mass. Measurement of total body rbc mass requires special radiolabeling techniques that are not amenable to general medical diagnostic work.
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- Of the many causes of megaloblastic anemia, the most common. are disorders resulting from cobalamin or folate deficiency. The clinical symptoms are. weakness, fatigue, shortness of breath and neurologic abnormalities. The presence of.
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INTRODUCTION Megaloblastic Anemia (MGA), also known as Pernicious Anemia, is a rare blood disorder characterized by the presence of large, structurally and visually abnormal, immature red blood cells (megaloblasts). Decreased numbers and immaturity of white blood cells (leukocytes) and blood platelets (thrombocytes) may also occur.
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- megaloblast. [meg′əlōblast′]. Etymology: Gk, megas + blastos, germ. an abnormally large nucleated immature erythrocyte that develops in large numbers in the bone marrow and is plentiful in the circulation in anemias associated with deficiency of vitamin B 12, folic acid, or intrinsic factor.Effective treatment is the intramuscular injection of vitamin B 12. megaloblastic, adj.egaloblast. [meg′əlōblast′]. Etymology: Gk, megas + blastos, germ. an abnormally large nucleated immature erythrocyte that develops in large numbers in the bone marrow and is plentiful in the circulation in anemias associated with deficiency of vitamin B 12, folic acid, or intrinsic factor.
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- Megaloblastic Anemia: Diagnosis and Treatment. Diagnosis. The complete hematologic picture includes: Large bone marrow precursor cells of neutrophils and erythrocytes (macro–ovalocytes) with an elevated mean corpuscular volume (MCV). Note: An elevated MCV may not be present if iron deficiency is concurrent.
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- Anemia is a frequent occurrence in systemic lupus erythematosus (SLE), affecting most patients at some time in the course of their disease.
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Hypochromic anemia Hypochromic anemia is a generic term for any type of anemia in which the red blood cells (erythrocytes) are paler than normal. (Hypo-refers to less, and chromic means color .) A normal red blood cell will have an area of pallor in the center of it; it is biconcave disk shaped. In hypochromic cells, this area of central pallor is increased.
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- Megaloblastic anemia is suspected in anemic patients with macrocytic indices. Diagnosis is usually based on peripheral smear. When fully developed, the anemia is macrocytic, with MCV > 100 fL/cell in the absence of iron deficiency, thalassemia trait, or renal disease. The smear shows macro-ovalocytosis, anisocytosis, and poikilocytosis. The RBC distribution width (RDW) is high.
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Hydrops fetalis Rh disease and ABO incompatibility disease are caused when a mother's immune system produces antibodies against the red blood cells of her unborn child. The antibodies cause the baby's red blood cells to be destroyed and the baby develops anemia.rythroblastosis fetalis refers to two potentially disabling or fatal blood disorders in infants: Rh incompatibility disease and ABO incompatibility disease.
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NCI Dictionary of Cancer Terms A gene formed when pieces of chromosomes 9 and 22 break off and trade places. The ABL gene from chromosome 9 joins to the BCR gene on chromosome 22, to form the BCR-ABL fusion gene. The changed chromosome 22 with the fusion gene on it is called the Philadelphia chromosome. The BCR-ABL fusion gene is found in most patients with chronic myelogenous leukemia (CML), and in some patients with acute lymphoblastic leukemia (ALL) or acute myelogenous leukemia (AML).
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Myeloproliferative Neoplasms Myelofibrosis (MF) Is a rare bone marrow cancer. It is one of a related group of blood cancers known as “myeloproliferative neoplasms (MPNs)” in which bone marrow cells that produce the blood cells develop and function abnormally.
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Hypochromic microcytic anemias Hypochromic microcytic anemias. Hypochromic microcytic anemias, characterized by the presence in the circulating blood of red cells that are smaller than normal and poorly filled with hemoglobin, fall into two main categories.
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hypochromic microcytic anemia hemorrhagic anemia anemia caused by the sudden and acute loss of blood; called also acute posthemorrhagic anemia. hypochromic anemia anemia in which the decrease in hemoglobin is proportionately much greater than the decrease in number of erythrocytes. hypochromic microcytic anemia any anemia with microcytes that are hypochromic (reduced in size and in hemoglobin content); the most common type is iron deficiency anemia.
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normocytic anemia microcytic anemia anemia characterized by microcytes (erythrocytes smaller than normal); see also hypochromic microcytic anemia and microcythemia. myelopathic anemia (myelophthisic anemia) leukoerythroblastosis. normochromic anemia that in which the hemoglobin content of the red blood cells is in the normal range.ypochromic microcytic anemia any anemia with microcytes that are hypochromic (reduced in size and in hemoglobin content); the most common type is iron deficiency anemia.
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anemia Switch to new thesaurus. refractory anaemia. sideroblastic anaemia, sideroblastic anemia, siderochrestic anaemia, siderochrestic anemia - refractory anemia characterized by sideroblasts in the bone marrow. anemia, anaemia - a deficiency of red blood cells.
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Hemolytic Disease of the Fetus and Newborn (HDFN) Hemolytic Disease of the Fetus and Newborn (HDFN) Hemolytic disease of the fetus and newborn (HDFN), often called erythroblastosis fetalis, is a blood disorder that occurs when the blood types of a mother and baby are incompatible. For reference, “Hemolytic” means breaking down of the red blood cells and “Erythroblastosis” refers to the making of immature red blood cells.
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Myelophthisic anemia Myelophthisic anemia. Myelophthisic anemia (or myelophthisis) is a severe type of anemia found in some people with diseases that affect the bone marrow. Myelophthisis refers to the displacement of hemopoietic bone-marrow tissue [1] either by fibrosis, tumors or granulomas.
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A Guide to Anemia Symptoms Anemia of Folate Deficiency. Folate deficiency is the lack of folic acid (one of the B vitamins) in the blood, which can cause a type of anemia known as megaloblastic anemia.nemia of Folate Deficiency. Folate deficiency is the lack of folic acid (one of the B vitamins) in the blood, which can cause a type of anemia known as megaloblastic anemia.