what is mixed connective tissue disease
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Mixed Connective Tissue Disease Mixed connective tissue disease is a rheumatic disease that has features shared by lupus, scleroderma, polymyosistis or dermatomyositis and rheumatoid arthritis. When symptoms of Mixed Connective Tissue Disease first appear, they may suggest that the person affected has any one of several rheumatic diseases.
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- A connective tissue disease is any disease that affects the parts of the body that connect the structures of the body together. Connective tissues are made up of two proteins: collagen and elastin. Collagen is a protein found in the tendons, ligaments, skin, cornea, cartilage, bone, and blood vessels.Elastin is a stretchy protein that resembles a rubber band and is the major component of ligaments and skin. When a patient has a connective tissue disease, the collagen and elastin are inflamed.ollagen is a protein found in the tendons, ligaments, skin, cornea, cartilage, bone, and blood vessels. Elastin is a stretchy protein that resembles a rubber band and is the major component of ligaments and skin.
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- Mixed connective tissue disease has signs and symptoms of a combination of disorders — primarily lupus, scleroderma and polymyositis. For this reason, mixed connective tissue disease is sometimes referred to as an overlap disease.
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Mixed Connective Tissue Disease (MCTD) Mixed connective tissue disease (MTCD) is a rare connective tissue disorder. MCTD is used to describe what may be an overlapping group of connective tissue disorders that cannot be diagnosed in more specific terms.These disorders include systemic lupus erythematosus, polymyositis, and scleroderma.mportant. It is possible that the main title of the report Mixed Connective Tissue Disease (MCTD) is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
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Connective tissue disease The classic collagen vascular diseases include: Systemic lupus erythematosus (SLE) – An inflammation of the connective tissues, SLE can afflict every organ system. It is up to nine times more common in women than men and strikes black women three times as often as white women.
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mixed connective tissue disease Medical Definition of mixed connective tissue disease. : a syndrome characterized by symptoms of various rheumatic diseases (as systemic lupus erythematosus, scleroderma, and polymyositis) and by high concentrations of antibodies to extractable nuclear antigens.
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Overview The precise cause of mixed connective tissue disease isn't known. Mixed connective tissue disease is an autoimmune disorder. In autoimmune disorders, your immune system — responsible for fighting off disease — mistakenly attacks healthy cells. In connective tissue diseases, your immune system attacks the fibers that provide the framework and support for your body. Researchers are working to identify proteins produced by the immune system that might cause mixed connective tissue disease.
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Connective Tissue Disease Connective tissue diseases are actually a group of medical diseases. A connective tissue disease is any disease that has the connective tissues of the body as a primary target of pathology.
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undifferentiated connective tissue disease An early stage of a connective tissue disease, in which the predominant organ of involvement or clinical form is not yet manifest. Cf Overlap syndrome, Palindromic rheumatism.
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Collagen vascular disease The connective tissue holds bones, ligaments, and muscles together. Collagen vascular disease is sometimes also called connective tissue disease. Some disorders classified as collagen vascular diseases affect your joints, skin, blood vessels, or other vital organs. Symptoms vary according to the specific disease.
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Connective Tissue Disease The autoimmune connective tissue diseases include systemic lupus erythematosus, rheumatoid arthritis, scleroderma, polymyositis, and dermatomyositis. These are considered classic connective tissue diseases. Each of these diseases has a classic presentation with typical findings that doctors can recognize during an examination. Each also has various typical blood test abnormalities and a variety of abnormal antibodies that are commonly found in blood.
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- This condition has many symptoms, including: 1  Pain in two or more joints. Almost all persons with mixed connective tissue disease have this symptom. Three out of four persons with the condition have arthritis and may have the swollen, deformed joints of rheumatoid arthritis.  Raynaud's phenomenon.
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Undifferentiated connective tissue disease Undifferentiated connective tissue disease is type of autoimmune disease, meaning the system of the body that is responsible for preventing infection (immune system) is attacking the body. The exact cause of autoimmune diseases is frequently unknown.
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- A connective tissue disease is any disease that affects the parts of the body that connect the structures of the body together. Connective tissues are made up of two proteins: collagen and elastin.Collagen is a protein found in the tendons, ligaments, skin, cornea, cartilage, bone, and blood vessels.Elastin is a stretchy protein that resembles a rubber band and is the major component of ligaments and skin. When a patient has a connective tissue disease, the collagen and elastin are inflamed.ollagen is a protein found in the tendons, ligaments, skin, cornea, cartilage, bone, and blood vessels. Elastin is a stretchy protein that resembles a rubber band and is the major component of ligaments and skin. When a patient has a connective tissue disease, the collagen and elastin are inflamed.
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Connective Tissue Disease Furthermore, the undifferentiated features may, themselves, disappear at which point there is no disease at all. When more than one autoimmune connective tissue disease is present in the same person their condition is often referred to as an “overlap” syndrome of connective tissue disease.
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Connective Tissue Disease 1 Lung disorders. Nearly 80% of the people with mixed connective tissue disease have some involvement of the lungs. Symptoms can include inflammation of the lining that covers the lungs and the inside of the chest, difficulty breathing or pulmonary hypertension.  Kidney disease.
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What is a connective tissue disease? Elastin is the major component of ligaments (tissues that attach bone to bone) and skin. In patients with connective tissue disease, it is common for collagen and elastin to become injured by inflammation. Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissues (autoimmunity). Diseases in which inflammation or weakness of collagen tends to occur are also referred to as collagen diseases.
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Connective Tissue Disease A Patient Overview. The term undifferentiated connective tissue disease (UCTD) is used to describe people who have symptoms and certain lab test results that look like a systemic autoimmune disorder or connective tissue disease.
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- Mixed connective tissue disease has features of three other connective tissue diseases: 1  Systemic lupus erythematosus (SLE) – An inflammatory disease that can affect many different organs. 2  Symptoms include fever, fatigue, joint pains, weakness, and skin rashes on the face, neck, and upper body.ixed connective tissue disease has features of three other connective tissue diseases: 1  Systemic lupus erythematosus (SLE) – An inflammatory disease that can affect many different organs. 2  Symptoms include fever, fatigue, joint pains, weakness, and skin rashes on the face, neck, and upper body.
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- (March 2013). A connective tissue disease is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs.March 2013). A connective tissue disease is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs.
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Connective Tissue Disease However, when a person has mixed connective tissue disorder, the symptoms aren't as severe or as widespread as they would be if the person has lupus, scleroderma, rheumatoid arthritis or other rheumatic disorder. This condition has many symptoms, including: 1  Pain in two or more joints. 2  Almost all persons with mixed connective tissue disease have this symptom. 3  Three out of four persons with the condition have arthritis and may have the swollen, deformed joints of rheumatoid arthritis. 4  Raynaud's phenomenon.
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- A connective tissue disease is any disease that affects the parts of the body that connect the structures of the body together. Connective tissues are made up of two proteins: collagen and elastin. Collagen is a protein found in the tendons, ligaments, skin, cornea, cartilage, bone, and blood vessels.ystemic lupus erythematosus lupus (SLE) —A disease that can cause inflammation of the connective tissue in every organ of the body, from the brain, skin, blood, to the lungs. It is nine times more common in women than men.
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MayoClinic Health Library Definition. Mixed connective tissue disease has signs and symptoms of a combination of disorders — primarily lupus, scleroderma and polymyositis. For this reason, mixed connective tissue disease is sometimes referred to as an overlap disease.In mixed connective tissue disease, the symptoms of the separate diseases usually don't appear all at once. Instead, they tend to occur in sequence over a number of years, which can make diagnosis more complicated.or this reason, mixed connective tissue disease is sometimes referred to as an overlap disease. In mixed connective tissue disease, the symptoms of the separate diseases usually don't appear all at once. Instead, they tend to occur in sequence over a number of years, which can make diagnosis more complicated.
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- Undifferentiated Connective Tissue Disease (UCTD) Undifferentiated connective tissue disorders are autoimmune connective tissue disorders with overlapping features of various other related disorders.
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Connective Tissue Disease In this Article. Connective tissue disease refers to a group of disorders involving the protein-rich tissue that supports organs and other parts of the body. Examples of connective tissue are fat, bone, and cartilage. These disorders often involve the joints, muscles, and skin, but they can also involve other organs and organ systems, including the eyes, heart, lungs, kidneys, gastrointestinal tract, and blood vessels.
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MayoClinic Health Library Definition. Mixed connective tissue disease has signs and symptoms of a combination of disorders — primarily lupus, scleroderma and polymyositis. For this reason, mixed connective tissue disease is sometimes referred to as an overlap disease.In mixed connective tissue disease, the symptoms of the separate diseases usually don't appear all at once. Instead, they tend to occur in sequence over a number of years, which can make diagnosis more complicated.Early signs and symptoms often involve the hands.or this reason, mixed connective tissue disease is sometimes referred to as an overlap disease. In mixed connective tissue disease, the symptoms of the separate diseases usually don't appear all at once. Instead, they tend to occur in sequence over a number of years, which can make diagnosis more complicated.