can statins cause muscle cramps in legs
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- If therapy is stopped, these benefits will be lost and cholesterol levels will return to pretreatment levels. Statins have several effects on muscle. They can cause muscle and leg cramps, myalgia (muscle pain), myositis (muscle inflammation) and rhabdomyolysis (Muscle breakdown). Rhabdomyolysis is a serious condition that often starts as muscle pain and may result ultimately in kidney failure.
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- Muscle effects. Statins can occasionally cause inflammation (swelling) and damage to your muscles. Speak to your doctor if you experience muscle pain, tenderness or weakness that cannot be explained (for example, not due to physical work).
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Statins and muscle spasms Statins and muscle spasms. Ken_Johnson. I have been taking Simva Statin for the past 3 years to lower my cholestreol which it has done. However I have also suffered from bad muscle spasms in my legs in the evening and at night. I decided to stop the statins and the spasms have gone immediately thank goodness ! I will never take this statin again but I know I have to still control my cholesterol.
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Why Do Statins Cause Muscle Pain? A Side Effect of Statins is Muscle Pain. About 5 to 10 percent of patients taking statins experience clinically significant side effects, which is higher than original reports. Symptoms may appear within the first six months of treatment or appear after several years.
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Could My Medicine Be Causing Excruciating Leg Cramps? The authors report that their analysis “suggest that the use of diuretics, statins, and LABAs promotes muscle cramping in older adults.” Although statins were less likely to cause such problems compared to diuretics or inhaled bronchodilators, they were linked to this problem. This may just be the tip of the iceberg.
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Statin side effects: Weigh the benefits and risks Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-mi-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins. Liver damage Occasionally, statin use could cause your liver to increase its production of enzymes that help you digest food, drinks and medications.
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- Figuring out if these are due to a statin can be tricky. Statin-related muscle problems usually appear within a few weeks of starting the drug. Be aware of muscle pain, cramps, stiffness, spasms, and weakness that can't be explained by arthritis, recent strenuous exercise, a fever, a fall, or other common causes.
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Statin side effects: Weigh the benefits and risks Muscle pain and damage The most common statin side effect is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult.habdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins.
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"Are leg cramps the same as ""muscle pain"" described in Lipitor symptoms?" There are usually other symptoms like weakness with the pain of statins. Statins can cause rhabdomyolosis. If you are having alot of cramping like that, I would definately go to the doc. Cramps can be caused by things like imbalance in electrolytes in your blood. He can probably help you out.
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- A: Statins like Crestor are generally well tolerated. Common side effects include headache, muscle aches, tenderness, or weakness, drowsiness, weakness, dizziness, nausea, vomiting, abdominal cramping and/or pain, bloating, gas, diarrhea, constipation, and rash. Other side effects reported with Crestor include arthralgia (joint pain).
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Overview Tasks that were once simple, such as climbing stairs or walking, may make you uncomfortable and tired while using statins. Muscle breakdown. Rhabdomyolysis, or the breakdown of muscle tissue, is a rare side effect of statins that can also cause muscle pain. This disease can cause life-threatening muscle damage. In addition to severe muscle pain, rhabdomyolysis can lead to liver damage, kidney failure, and, in rare cases, death. According to the FDA, the following statins contain specific warnings on the package inserts about muscle pain and rhabdomyolysis: lovastatin extended-release (Altoprev)
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Overview The development of the condition rhabdomyolysis, or the breakdown of muscle tissue, is rare, but it’s another possible side effect. This disease can cause painful, life-threatening muscle damage. In addition to severe muscle pain, it can lead to liver damage, kidney failure, and, in rare cases, death. Rhabdomyolosis sounds scary, but the average statin user does not have to worry about developing this disorder.
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Managing Muscle Pain Related to Cholesterol Medication Unfortunately, some people may experience muscle pain or weakness while taking statins. The pain may be minor such as soreness or stiffness. However, muscle pain, particularly if severe and accompanied by dark-colored urine, may be an indication of a more serious, life-threatening problem called rhabdomyolysis.
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Why Do Statins Cause Muscle Pain? The Reason Why Statins Cause Muscle Pain. Previous studies show that the gene atrogin-1 turns on at the beginning stages of the breakdown of muscle (muscle wasting), which is associated with illnesses such as cancer, sepsis, and AIDS. When the atrogin-1 gene is not active, muscle wasting does not occur.
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Statin side effects: Weigh the benefits and risks Muscle pain and damage The most common statin side effect is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult.ery rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-mi-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death.
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How Can I Avoid Leg Cramps When Taking Cholesterol Medicine? Have your physician test your vitamin E levels. A 2010 review published in Medical Hypotheses suggests that statin use can cause a lowering of vitamin E levels in the blood that could result in statin myopathy, or muscle cramps. If your levels are low, your physician can advise you on taking a vitamin E supplement, which might help relieve your leg cramps.
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- Statins have several effects on muscle. They can cause muscle and leg cramps, myalgia (muscle pain), myositis (muscle inflammation) and rhabdomyolysis (Muscle breakdown). Rhabdomyolysis is a serious condition that often starts as muscle pain and may result ultimately in kidney failure.
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- Treating Statin Muscle Pain. The reason statins cause muscle pain is not known. A lot of research and studies have been conducted. The Journal of the American Physical Therapy Association published a study that highlights statins and muscle pain and attempts to correlate them.his disease can cause painful, life-threatening muscle damage. In addition to severe muscle pain, it can lead to liver damage, kidney failure, and, in rare cases, death. Rhabdomyolosis sounds scary, but the average statin user does not have to worry about developing this disorder.
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Statin side effects: Weigh the benefits and risks Muscle pain and damage The most common statin side effect is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult.
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Muscle Problems With Statins If the muscle-related symptoms consisted only of pain and perhaps a small elevation in CK blood levels, and if continued statin therapy is deemed to be important, there are a few approaches that may allow the successful resumption of a statin.
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Side Effects of Statins Common side effects of all statins. Side effects reported by some people include muscle pain and digestive problems. Muscle pain is the most common side effect caused by statin use. A 2005 study found that over 10 percent of people taking high-dose statins had muscle pain. Muscle pain can be uncomfortable.
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Zetia However, myopathy and rhabdomyolysis are known adverse reactions to statins and other lipid-lowering drugs. In clinical trials, the incidence of creatine phosphokinase (CPK) >10 × ULN was 0.2% for Zetia vs. 0.1% for placebo, and 0.1% for Zetia coadministered with a statin vs. 0.4% for statins alone.
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What to do when you suspect a statin causes muscle pain Muscle aches on statin drugs like Lipitor are common. Sometimes, but not always, they can cause muscle inflammation as well, with evidence of muscle breakdown in the blood. It's important to emphasize that not all cases of muscle aches due to statins have abnormal blood results. If the muscle aches stop while off the statin, it is likely that the statin caused them. In that case, it would be worth a try of the medicine again. If they came back on, I would not recommend taking it further.
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- Statins may affect certain enzymes present in muscle cells that handle muscle growth. This may cause the muscle aches. If you experience muscle pain as a result of taking statins, immediately let your doctor know. There are some things that your doctor can do to help. Your doctor may start by taking you off of the drug for a while to see how your body responds. Your muscle pain could be due to the statin, or it might simply be a byproduct of getting older. There are several statin drug options, so your doctor may prescribe a different drug and see if you have a better reaction.
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Statins and Myoglobin: How Muscle Pain and Weakness Progress to Heart, Lung and Kidney Failure Rhabdomyolysis is a condition where the muscles rapidly disintegrate due to an injury, often, for example, physical trauma following an accident. But Rhabdomyolysis is also a rare side effect of statins -- essentially where the muscle pain and weakness are extreme. Some people react immediately to statin therapy with severe rhabdomyolysis, and it is often fatal, due to acute renal failure (ARF).