where in the world is sickle cell anaemia most common
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- Sickle cell disease affects millions of people worldwide. It is most common among people whose ancestors come from Africa; Mediterranean countries such as Greece, Turkey, and Italy; the Arabian Peninsula; India; and Spanish-speaking regions in South America, Central America, and parts of the Caribbean.ickle cell disease is the most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans. The disease is estimated to occur in 1 in 500 African Americans and 1 in 1,000 to 1,400 Hispanic Americans.
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Genes and human disease Sickle cell anemia affects millions throughout the world. It is particularly common among people whose ancestors come from Sub-Saharan Africa, South America, Cuba, Central America, Saudi Arabia, India, and Mediterranean countries such as Turkey, Greece, and Italy. In the Unites States, it affects around 72,000 people, most of whose ancestors come from Africa.
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The Global HIV/AIDS Epidemic 1 According to WHO, sub-Saharan Africa is the most affected region, with 24.7 million people living with HIV in 2013. 2  Seventy-one percent of all people who are living with HIV in the world live in this region.3  HIV is the world’s leading infectious killer.he Global HIV/AIDS Epidemic. HIV, the virus that causes AIDS, is one of the world’s most serious health and development challenges: 1  According to the World Health Organization (WHO) ,
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- Sickle cell anemia is a genetic disease with severe symptoms, including pain and anemia. The disease is caused by a mutated version of the gene that helps make hemoglobin  a protein that carries oxygen in red blood cells.People with two copies of the sickle cell gene have the disease.People who carry only one copy of the sickle cell gene do not have the disease, but may pass the gene on to their children. This is a chain of causation. What happens at the DNA level propagates up to the level of the complete organism.NA and Mutations : A case study of the effects of mutation: Sickle cell anemia. The mutations that cause sickle cell anemia have been extensively studied and demonstrate how the effects of mutations can be traced from the DNA level up to the level of the whole organism.
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Modern Human Variation: Distribution of Blood Types Americas, Africa, Asia and Europe.. The A allele apparently was absent among Central and South American Indians. Distribution of the A type blood allele in native populations of the world. The O blood type (usually resulting from the absence of both A and B alleles) is very common around the world. About 63% of humans share it. Type O is particularly high in frequency among the indigenous populations of Central and South America, where it approaches 100%.
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In US, celiac disease diagnosis is most common among patients with Punjabi ancestry 1 Celiac disease was most common among Americans from the Punjab region of India. 2  Celiac disease was significantly less common among U.S. residents of South Indian, East Asian and Hispanic ancestry.  The rate of celiac disease among patients of Jewish and Middle Eastern ethnicities was similar to that of other Americans.
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In US, celiac disease diagnosis is most common among patients with Punjabi ancestry This research gives insights into celiac disease found in the U.S. Among patients who underwent testing for celiac disease: 1  Celiac disease was most common among Americans from the Punjab region of India.  Celiac disease was significantly less common among U.S. residents of South Indian, East Asian and Hispanic ancestry.
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- Sickle-cell disease. Sickle-cell disease (SCD) is a group of blood disorders typically inherited from a person's parents.[2] The most common type is known as sickle-cell anaemia (SCA). It results in an abnormality in the oxygen-carrying protein haemoglobin (hemoglobin S) found in red blood cells.
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Hemoglobinopathy Hemoglobinopathies are inherited single-gene disorders; in most cases, they are inherited as autosomal co-dominant traits. Common hemoglobinopathies include sickle-cell disease. It is estimated that 7% of world's population (420 million) are carriers, with 60% of total and 70% pathological being in Africa. Hemoglobinopathies are most common in ethnic populations from Africa, the Mediterranean basin and Southeast Asia.
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Sickle-cell disease sickle cell disease. Sickle cell anemia, a common form of sickle cell disease, is caused by a particular mutation in the HBB gene. This mutation results in the production of an abnormal version of beta-globin called hemoglobin S or HbS. In this condition, hemoglobin S replaces both beta-globin subunits in hemoglobin.
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Hematology in Children Sickle cell trait Child inherits Hgb S from one parent and Hgb A from another Most common in African American children Can result in: Vasoocclusive crisis (thrombotic crisis), aplastic crisis, sequestration crisis, and hyperhemolytic crisis.
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Tularemia Tularemia is caused by the bacterium Francisella tularensis. The disorder most commonly occurs in North America and parts of Europe and Asia. In the US, this disease is found more often in Missouri, South Dakota, Oklahoma, and Arkansas. Although outbreaks can occur in the United States, they are rare.
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Snowdon Snowdon (Welsh: Yr Wyddfa, [əɾ ˈwɨ̞ðva]) is the highest mountain in Wales, at an elevation of 1,085 metres (3,560 ft) above sea level, and the highest point in the British Isles outside the Scottish Highlands.he name Snowdon is from the Old English for snow hill, while the Welsh name – Yr Wyddfa – means the tumulus , which may refer to the cairn thrown over the legendary giant Rhitta Gawr after his defeat by King Arthur.
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- It occurs when a child inherits two sickle hemoglobin genes, one from each parent. About 2,000 babies are born with sickle cell disease each year in the United States. People who inherit only one sickle hemoglobin gene are carriers (sickle cell trait) and do not have anemia or painful sickle cell crises.
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Most common type of anemia Most common type of anemia. Most common type of anemia: Iron deficiency anemia. Iron deficiency anemia is the most common type of anemia. The most common cause of iron deficiency anemia in the United States is blood loss. Therefore, we can say that anemia of blood loss is the most common type of anemia in this country.
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- Tay-Sachs disease occurs most frequently among people whose ancestors come from Eastern and Central European Jewish communities (Ashkenazi Jews), from certain French Canadian communities in Quebec, the Old Order Amish community in Pennsylvania and from the Cajun community of Louisiana.
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- Sickle cell anemia. Sickle cell anemia is another of the most common, inherited, single-gene disorders in African-Americans. About one in 500 African-American babies is born with sickle cell anemia. About one in 12 African-American people carries the gene for this disease.
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Where is scarlet fever mostly found in the world? Scarlet Fever is commonly found in Asia and Europe , mostly England. Be careful of what you drink and cover your mouth and nose when somebody is sneezing or coughing near you.….
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- Anemia resulting from lack of sufficient iron to synthesize hemoglobin is the most common hematological disease in infants and children. It has been estimated that 30% of the global population suffers from iron deficiency anemia (IDA), and most of those affected live in the developing countries.
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Malaria Resistance and Sickle Cell Trait Despite the disease’s lethal symptoms, it protects the carrier from malaria, which is why sickle cell alleles are most common in people of African descent (about 7% of people of African descent carry an allele), and other areas where malaria is prevalent. [3]
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Modern Human Variation: Distribution of Blood Types Americas, Africa, Asia and Europe.. AB + 1 person in 29 or 3.2%. AB - 1 person in 167 or 0.7%. O blood type (usually resulting from the absence of both A and B alleles) is very common around the world. It is particularly high in frequency among the indigenous populations of Central and South America, where it approaches 100%.
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Overview Introduction. Sickle cell anaemia is a serious inherited blood disorder where the red blood cells, which carry oxygen around the body, develop abnormally. The disorder mainly affects people of African, Caribbean, Middle Eastern, Eastern Mediterranean and Asian origin.
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Cuba The current Ebola outbreak that began in March 2014 is the largest in history. The three most affected countries are Guinea, Liberia and Sierra Leone, and cases have also been reported in Nigeria, Senegal, Spain and the United States. Live Science is covering the outbreak; check back for updates on the outbreak.
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Malaria How Common Is Malaria? Forty percent of the world's population is at risk for contracting malaria from infected mosquitoes, primarily in tropical and subtropical regions. Worldwide, there are 300 to 500 million cases of malaria and more than one million deaths from malaria each year.
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Adult T-cell lymphoma (ATLL) Adult T-cell lymphoma (ATLL) is rare in countries such as Australia and North America. It is more prevalent in countries where infection with HTLV-1 is common, such as Japan, China, the Caribbean, South and Central America and West Africa.
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Emerging Treatment Options for Sickle Cell Anemia Published Online: Monday, Dec 15, 2014. Tweet. Sickle cell disease is a rare genetic condition that affects 90,000 to 100,000 Americans, mostly African Americans. A person with sickle cell disease has red blood cells that are hard, sticky, and C-shaped (like the farm tool the sickle).ickle cell disease is a rare genetic condition that affects 90,000 to 100,000 Americans, mostly African Americans.