what is onabotulinumtoxina
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OnabotulinumtoxinA OnabotulinumtoxinA (Botox®) is a prescription injection approved to: 1  Treat severe underarm sweating that has not responded to other treatments. 2  Treat eyelid twitching or spasms (known medically as blepharospasm) 3  Temporarily improve the appearance of wrinkles between the eyebrows (frown lines) and crow's feet.
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onabotulinumtoxinA What is onabotulinumtoxinA (Botox)? OnabotulinumtoxinA (Botox), also called botulinum toxin type A, is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity. Botox is used to treat cervical dystonia (severe spasms in the neck muscles), muscle spasms in the arms and hands, and severe underarm sweating (hyperhidrosis).
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Overview Botulinum toxin (abbreviated either as BTX or BoNT) is produced by Clostridium botulinum, a gram-positive anaerobic bacterium. The clinical syndrome of botulism can occur following ingestion of contaminated food, from colonization of the infant gastrointestinal tract, or from a wound infection.
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Orexin-A Orexin-A, also known as hypocretin-1, is a naturally occurring neuropeptide and orexin isoform. The orexinergic nucleus in the lateral hypothalamus is the primary orexin projection system in the brain.aking orexin-A also increases arousal, alertness, attention, and muscle tone. Orexin-A has no effect on subjects who are well rested. The most important side effect orexin-A is thought to have is counteracting the effects of narcolepsy.
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A Testing Breakthrough For Hidden Cancers The Oncoblot blood test identifies a specific type of protein in the blood, ENOX2*, which exists only on the surface of a malignant cancer cell. The ENOX2 proteins are shed into the circulation and can be detected in the blood.
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- Botox Injections. Facts on Botox Injections. Botulinum toxin (Botox, onabotulinumtoxinA) is a material that has been known for over a century and used for medical purposes for more than 50 years. Its initial uses were for lazy eye (strabismus), blepharospasm (inability to move the eyelids in certain ways), and wry neck (cervical dystonia).
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- Knowledge center. Botox is a drug made from a neurotoxin produced by the bacterium Clostridium botulinum called botulinum toxin. It is used medically to treat certain muscular conditions and cosmetically remove wrinkles by temporarily paralyzing muscles. Botox is the most popular cosmetic surgery treatment, with more than 6 million Botox treatments administered each year. 2  Botox is a neurotoxin derived from Clostridium botulinum, an organism found in the natural environment where it is largely inactive and non-toxic.
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Myobloc Myobloc®. (rimabotulinumtoxinB) Injection. Distant Spread of Toxin Effect. Postmarketing reports indicate that the effects of MYOBLOC (botulinum toxin type b) and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects.
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Overview Waldenstrom macroglobulinemia (mak-roe-glob-u-lih-NEE-me-uh) is a rare type of cancer that begins in the white blood cells. If you have Waldenstrom macroglobulinemia, your bone marrow produces too many abnormal white blood cells that crowd out healthy blood cells. The abnormal white blood cells produce a protein that accumulates in the blood, impairs circulation and causes complications. Waldenstrom macroglobulinemia is considered a type of non-Hodgkin's lymphoma.
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BOTULINUM TOXIN Botulinum toxin, one of the most poisonous biological substances known, is a neurotoxin produced by the bacterium Clostridium botulinum. C. botulinum elaborates eight antigenically distinguishable exotoxins (A, B, C 1, C 2, D, E, F and G).
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Botulism Botulinum Toxin. Botulism is an intoxication caused by botulinum toxin, which is produced by Clostridium botulinum and, rarely, by other Clostridium species. Seven antigenically distinct toxin types (A, B, C, D, E, F, G) have been identified.ound Botulism. 1  Wound botulism is caused by infection of a contaminated wound with C botulinum and subsequent absorption into the circulation of locally produced toxin. 2  C botulinum is a natural contaminant of soil throughout the United States (Smith 1978).
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BOTULINUM TOXIN Introduction. Botulinum toxin, also called “miracle poison,” is one of the most poisonous biological substances known.[ 1 ] It is a neurotoxin produced by the bacterium Clostridium botulinum, an anaerobic, gram-positive, spore-forming rod commonly found on plants, in soil, water and the intestinal tracts of animals.
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Why Personal Relationships Are Important Healthy relationships are a vital component of health and wellbeing. There is compelling evidence that strong relationships contribute to a long, healthy, and happy life.
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Botulism 1 Clostridium botulinum is a bacterium that produces dangerous toxins (botulinum toxins) under low-oxygen conditions. 2  Botulinum toxins are one of the most lethal substances known.  Botulinum toxins block nerve functions and can lead to respiratory and muscular paralysis.
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Dysport Botulinum toxin type A, the active ingredient in Dysport® (abobotulinumtoxinA), is a purified neurotoxin type A complex produced by fermentation of the bacterium Clostridium botulinum type A, Hall Strain. It is purified from the culture supernatant by a series of precipitation, dialysis, and chromatography steps.
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Dysport Dysport for Injection (abobotulinumtoxinA), also called botulinum toxin type A, is made from the bacteria that causes botulism and is used to treat cervical dystonia (severe spasms in the neck muscles). It is also used to temporarily lessen the appearance of facial wrinkles.
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Tuberculosis The tuberculin skin test (TST), also called Mantoux skin test, shows if a person has been infected. QuantiFERON- TB test is a blood based test for diagnosing latent tuberculosis (TB) infection (LTBI). However, it is not useful yet for many people and is not used frequently.
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Clostridium botulinum From Wikipedia, the free encyclopedia. Clostridium botulinum is a Gram-positive, rod-shaped, anaerobic, spore-forming, motile bacterium with the ability to produce the neurotoxin botulinum.. botulinum is a diverse group of bacteria initially grouped together by their ability to produce botulinum toxin and now known as four distinct groups, C. botulinum groups I-IV.
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- An example of a neurotoxin is the toxin secreted. by Clostridium botulinum, the most poisonous substance known. The fatal dose of botulinum toxin A by. injection or inhalation is about 1 nanogram (billionth of a gram) per kilogram.
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Clostridium botulinum From Wikipedia, the free encyclopedia. Clostridium botulinum is a Gram-positive, rod-shaped, anaerobic, spore-forming, motile bacterium with the ability to produce the neurotoxin botulinum.
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Purified protein derivative (PPD) skin tests A PPD test involves injecting small amounts of protein from the mycobacteria that cause tuberculosis into the skin. PPD stands for 'purified protein derivative', indicating that the substance injected is non-infectious. This is known as the Mantoux-method TST (tuberculin skin test) . PPD is only recommended in people who have not had a prior positive test. It should be repeated annually in anyone who is at high-risk of acquiring TB.
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- Botulinum toxin type A, the active ingredient in DYSPORT® (abobotulinumtoxinA), is a purified neurotoxin type A complex produced by fermentation of the bacterium Clostridium botulinum type A, Hall Strain. It is purified from the culture supernatant by a series of precipitation, dialysis, and chromatography steps.
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Toxins Bacterial Toxins. Botulinum toxin, produced by the bacteria Clostridium botulinum, is the most poisonous substance known. The bacteria grows on, e.g., poorly preserved food and causes a severe form of food-poisoning (botulism).hey usually consist of an amino acid chain which can vary in molecular weight between a couple of hundred (peptides) and one hundred thousand (proteins). They may also be low-molecular organic compounds. Toxins are produced by numerous organisms, e.g., bacteria, fungi, algae and plants.
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Botulinum toxin Infection with the bacterium may result in a potentially fatal disease called botulism. Botulinum is the most acutely lethal toxin known, with an estimated human median lethal dose (LD50) of 1.3–2.1 ng/kg intravenously or intramuscularly and 10–13 ng/kg when inhaled.
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- The Test Sample. Thyroglobulin is a protein produced by the thyroid gland. This test measures the amount of thyroglobulin in the blood. The thyroid gland helps to regulate the rate at which the body uses energy. It is a small butterfly-shaped organ that lies flat against the windpipe in the throat and is composed primarily of very small, ball-shaped structures called follicles that produce and store thyroglobulin (Tg). Thyroglobulin then breaks down as needed into the thyroid hormones T4 (thyroxine) and T3 (triiodothyronine).
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Botox Botox (onabotulinumtoxinA), also called botulinum toxin type A, is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles. Botox is used to treat cervical dystonia (severe spasms in the neck muscles). It is also used to treat muscle spasms (stiffness) in the upper limbs (elbows, wrists, fingers) or lower limbs (ankles, toes). Botox is also used to treat severe underarm sweating (hyperhidrosis).