what meds cause hyponatremia
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Overview Many possible conditions and lifestyle factors can lead to hyponatremia, including: 1  Certain medications. Some medications, such as some water pills (diuretics), antidepressants and pain medications, can cause you to urinate or perspire more than normal. 2  Heart, kidney and liver problems.
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- In hypernatremia, the level of sodium in blood is too high. Hypernatremia involves dehydration, which can have many causes, including not drinking enough fluids, diarrhea, kidney dysfunction, and diuretics.ypernatremia typically causes thirst. The most serious symptoms of hypernatremia result from brain dysfunction. Severe hypernatremia can lead to confusion, muscle twitching, seizures, coma, and death. The diagnosis is based on blood tests indicating that the sodium level is high.
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Hyponatremia High volume hyponatremia can occur from heart failure, liver failure, and kidney failure. Conditions that can lead to falsely low sodium measurements include high protein levels such as in multiple myeloma, high blood fat levels, and high blood sugar. Treatment is based on the underlying cause. Correcting hyponatremia too quickly can lead to complications.
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benazepril and hydrochlorothiazide DRUG INTERACTIONS: Combining benazepril with potassium supplements, potassium containing salt substitutes, and potassium conserving diuretics such as amiloride (Moduretic), spironolactone (Aldactone), and triamterene (Dyazide, Maxzide), can lead to dangerously high blood levels of potassium.
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Medicine News Risk factors for the development of hyponatremia with SSRIs include older age, female gender, concomitant use of diuretics, low body weight, and lower baseline serum sodium concentration.
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Which Antidepressants Are Linked to Greater Hyponatremia Risk? the MPR take: Hyponatremia can be a potentially dangerous side effect of certain antidepressant medications. In a recent study published in the journal Psychosomatics, researchers review the incidence and odds ratios for hyponatremia based on antidepressant class.
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Low blood sodium in older adults: A concern? Severe hyponatremia can cause seizures, coma and even death. Hyponatremia is more common in older adults because they're more likely to take medications or have medical conditions that put them at risk of the disorder. These risk factors include: 1  Drugs that make you urinate more (diuretics).
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- The main causes of hyponatremia in hypo-osmolar patients. with high levels of sodium in the urine are syndrome of inap-. propriate antidiuretic hormone secretion, medications, renal. disorders, endocrine deficiencies, and reset osmostat syndrome. The Author.
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Overview Risk factors. The following factors may increase your risk of hyponatremia: 1  Age. 2  Older adults may have more contributing factors for hyponatremia, including age-related changes, taking certain medications and a greater likelihood of developing a chronic disease that alters the body's sodium balance. 3  Certain drugs.
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Lisinopril Side Effects May Include Hyponatremia In two of the cases, patients were reportedly given lisinopril a second time, and their serum sodium levels dropped once again. This led the researchers to conclude that the hyponatremia condition was likely a direct result of the medication, and not other factors, according to Van Amburgh.
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Hyponatremia Medication Used for hyponatremia associated with congestive heart failure, liver cirrhosis, and syndrome of inappropriate antidiuretic hormone secretion. Initiate or reinitiate in hospital environment only. Duration of use is limited to 30 days to minimize risk of liver injury.
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- Hyponatremia may result from excess fluid in the body relative to a normal amount of sodium, or it may be due to a loss of sodium and body fluid. Symptoms are nonspecific and can include: mental changes, headache, nausea and. vomiting, tiredness, muscle spasms, and. seizures.
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- Hyponatremia associated with diuretics can be associated with overt clinical or physiologic evidence of hypovolemia. Since evidence of hypovolemia might be subtle, studies to define physiologic evidence of hypovolemia, such as measurement of the renin angiotensin system, can help differentiate the various causes of hyponatremia.
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- The list of signs and symptoms mentioned in various sources for Hyponatremia includes the 10 symptoms listed below: 1  Low blood sodium level. 2  Nausea - severe hyponatremia. 3  Vomiting - severe hyponatremia. 4  Headache - severe hyponatremia. 5  Malaise - severe hyponatremia.  Confusion - severe hyponatremia.
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Which Antidepressants Are Linked to Greater Hyponatremia Risk? Antidepressant-induced hyponatraemia can cause significant morbidity, complications and mortality. It is mostly associated with the use of SSRIs, but its frequency and class-specificity are uncertain.
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Hyponatremia in Emergency Medicine Clinical Presentation The patient's medication list should be examined for drugs known to cause hyponatremia. Hyponatremia has been noted in patients with poor dietary intake who consume large amounts of beer (called beer potomania) and after use of the recreational drug N- methyl-3,4-methylenedioxyamphetamine (ie, MDMA or ecstasy).
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Samsca Patients should be in a hospital for initiation and re-initiation of therapy to evaluate the therapeutic response and because too rapid correction of hyponatremia can cause osmotic demyelination resulting in dysarthria, mutism, dysphagia, lethargy, affective changes, spastic quadriparesis, seizures, coma and death.
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- Causes of Hyponatremia with hypokalemia: The following medical conditions are some of the possible causes of Hyponatremia with hypokalemia. There are likely to be other possible causes, so ask your doctor about your symptoms. 1  Congenital adrenal hyperplasia. 2  Water intoxication. 3  Gastroenteritis. 4  Inappropriate formula preparation. 5  Pyloric stenosis.
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Learn how UpToDate can help you. As with other diuretic-induced fluid and electrolyte complications, hyponatremia often develops within the first one to two weeks of therapy if diuretic dose and dietary intake remain relatively constant (figure 1) [1,3,11].
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Hyponatremia Hyponatremia is decrease in serum sodium concentration < 136 mEq/L caused by an excess of water relative to solute. Common causes include diuretic use, diarrhea, heart failure, liver disease, renal disease, and the syndrome of inappropriate ADH secretion (SIADH).
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- Hypernatremia typically causes thirst. The most serious symptoms of hypernatremia result from brain dysfunction. Severe hypernatremia can lead to confusion, muscle twitching, seizures, coma, and death. The diagnosis is based on blood tests indicating that the sodium level is high. Hypernatremia is treated by replacing fluids. In all but the mildest cases, dilute fluids (containing water and a small amount of sodium in carefully adjusted concentrations) are given intravenously.
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- Hyponatremia signs and symptoms may include: 1  Nausea and vomiting. 2  Headache. 3  Confusion. 4  Loss of energy and fatigue. 5  Restlessness and irritability. 6  Muscle weakness, spasms or cramps. 7  Seizures. 8  Coma.
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sertraline - oral, Zoloft Older adults may be more sensitive to the side effects of this drug, especially bleeding or loss of coordination. Older adults may also be more likely to develop a type of salt imbalance (hyponatremia), especially if they are also taking water pills (diuretics).