what is idiotypic interaction immunology
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Idiotype The idiotype is based upon the variable region (labeled VL and VH in the diagram.). In immunology, an idiotype is a shared characteristic between a group of immunoglobulin or T cell receptor (TCR) molecules based upon the antigen binding specificity and therefore structure of their variable region.he variable region of antigen receptors of T cells (TCRs) and B cells (immunoglobulins) contain complementarity determining regions (CDRs) with unique amino acid sequences. They define the surface and properties of the variable region, determining the antigen specificity and therefore the idio tope of the molecule.
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Hypocomplementemic urticarial vasculitis Hypocomplementemic urticarial vasculitis: A rare condition characterized by the presence of recurring urticarial vasculitis, arthralgia or arthritis and hypocomplementemia. Hypocomplementemia involves a reduction or absence of blood complement which is a part of the body's immune system which destroying invading bacteria or other pathogens. More detailed information about the symptoms, causes, and treatments of Hypocomplementemic urticarial vasculitis is available below. Symptoms of Hypocomplementemic urticarial vasculitis Click to Check
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immunosuppression 1 the administration of agents that significantly interfere with the ability of the immune system to respond to antigenic stimulation by inhibiting cellular and humoral immunity. Corticosteroids; cytotoxic drugs, including antimetabolites and alkylating agents; antilymphocytic antibodies; and irradiation may produce immunosuppression.
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Epizootic Not to be confused with Epizoic. In epizoology, an epizootic (from Greek: epi- upon + zoon animal) is a disease event in a nonhuman animal population, analogous to an epidemic in humans. An epizootic may be: restricted to a specific locale (an outbreak), general (an epizootic) or widespread (panzootic).
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ReviewPrinciples of vaccine designâLessons from nature Immune responses to vaccination or infection. An antigen-presenting cell (APC) is the link between innate and adaptive immune responses. After engulfment, a pathogen is processed and parts of it are presented by the major histocompatibility complex (MHC) to the T cell receptor (TCR).
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Antigen-presenting cell An antigen-presenting cell (APC) or accessory cell is a cell that displays foreign antigens complexed with major histocompatibility complexes (MHCs) on their surfaces; this process is known as antigen presentation. T-cells may recognize these complexes using their T-cell receptors (TCRs).ntigen-presenting cells fall into two categories: professional and non-professional. T cells cannot recognize, and therefore cannot respond to, 'free' antigen. T cells can only 'see' an antigen that has been processed and presented by cells via carrier molecules like MHC and CD1 molecules.
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- In addition to immune rejection, another concern about xenotransplantation is the risk of transmittingviruses and other pathogens from one species to another. —
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This Is MS Multiple Sclerosis Community: Knowledge & Support A list of immunosuppressant drugs is given on the transplant rejection page. http://en.wikipedia.org/wiki/Immunostimulator. Immunostimulators are the drugs which stimulate the immune system by inducing activation or increasing activity of any of its components.his is typically done using drugs, but may involve surgery (splenectomy), plasmapharesis, or radiation. A person who is undergoing immunosuppression, or whose immune system is weak for other reasons (for example, chemotherapy and HIV) is said to be immunocompromised.
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- OrthoInfo Iliac Apophysitis Page 1 of 3 Iliac Apophysitis INTRODUCTION You have been diagnosed with iliac apophysitis. This is a mechanical overloading injury at the tendons that originate at the front of the pelvis above the hip. This may also be referred to as an avulsion fracture or tendonitis of the anterior thigh muscles. The pain improves with rest and symptomatic treatment. BACKGROUND Iliac apophysitis is one form of several apophyseal injuries, which can occur in skeletally immature patients between the ages of 12 and 18. An apophysis is the anatomic term used to
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- T-cell immunodeficiency, congenital alopecia, and nail dystrophy is a type of severe combined immunodeficiency (SCID), which is a group of disorders characterized by an almost total lack of immune protection from foreign invaders such as bacteria and viruses.-cell immunodeficiency, congenital alopecia, and nail dystrophy is a rare disorder. It has been diagnosed in only a few individuals, almost all of whom are members of a large extended family from a community in southern Italy.
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- While identical to understand its ramification. When your cat shows symptoms by including hyperthyroidism or autoimmune disease that attacks your muscles underactive (hypothyroidism and hyperthyroidism in iodine contains many antioxidant OPC. (Oligomeric Proanthocyanidin) consistency.hile identical to understand its ramification. When your cat shows symptoms by including hyperthyroidism or autoimmune disease that attacks your muscles underactive (hypothyroidism and hyperthyroidism in iodine contains many antioxidant OPC. (Oligomeric Proanthocyanidin) consistency.
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Hypogammaglobulinemia Hypogammaglobulinemia is a type of primary immunodeficiency disease in which not enough gamma globulins exist in the blood (thus hypo- + gamma + globulin + -emia). This entails that not enough antibodies exist, which impairs the immune system. Hypogammaglobulinemia is a characteristic of common variable immunodeficiency.
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- Molecular mimicry, also called epitopic and antigenic mimicry, is one of the leading theories that attempt to explain why the immune system turns on its own body in autoimmune diseases such as multiple sclerosis, rheumatoid arthritis and type 1 diabetes.
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- Etymology. Idiot is a word derived from the Greek ἰδιώτης, idiōtēs (person lacking professional skill, a private citizen, individual), from ἴδιος, idios (private, one's own). In Latin the word idiota (ordinary person, layman) preceded the Late Latin meaning uneducated or ignorant person.n modern English usage, the terms idiot and idiocy describe an extreme folly or stupidity, and its symptoms (foolish or stupid utterance or deed). In psychology, it is a historical term for the state or condition now called profound intellectual disability.
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- n acronym for. (Pathology) acquired immune (or immuno-)deficiency syndrome: a condition, caused by a virus, in which certain white blood cells (lymphocytes) are destroyed, resulting in loss of the body's ability to protect itself against disease.
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- Hypersensitivity to valacyclovir or acyclovir. Thrombotic thrombocytopenic purpura (TTP)/hemolytic uremic syndrome (HUS) reported in patients with advanced HIV disease and in allogenic bone marrow transplant and renal transplant recipients.
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vaccine anti-idiotype vaccine. antibody made to antigenic determinants located in the variable domains of immunoglobulin molecules. Proposed as a means of regulating antibody responses and also as a substitute antigen for vaccination.
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Major-Histocompatibility-Complex Class I Alleles and Antigens in Hematopoietic-Cell Transplantation HLA class I antigen mismatches that are serologically detectable confer an enhanced risk of graft failure after hematopoietic-cell transplantation. Transplants from donors with a single class I allele mismatch that is not serologically detectable may be used without an increased risk of graft failure.
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Alexithymia Alexithymia is prevalent in approximately 10% of the general population and is known to be comorbid with a number of psychiatric conditions. The term alexithymia was coined by psychotherapist Peter Sifneos in 1973.
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- Syndrome, autoimmune polyglandular (APS): A genetic autoimmune disease with an extraordinary array of clinical features but characterized most often by at least 2 of the following 3 findings: hypoparathyroidism -- underfunction of the parathyroid glands which control calcium, candidiasis (yeast infection), and adrenal insufficiency (underfunction of ...
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- The autoimmune-like hepatitis that has been described with minocycline has not been linked to doxycycline, despite similarities in chemical structure and similar indications and uses, perhaps because it is used less frequency in a low dose, long term regimen.he cause of the idiosyncratic liver injury associated with doxycycline is unknown, but several features (short latency, recurrence with reexposure) suggest an immunoallergic etiology.
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Stem Cell Therapy for Knees A particularly severe form of the contact injury is called the unhappy triad or O'Donaghue's triad, and involves the anterior cruciate ligament, the medial collateral ligament, and the medial meniscus.Presently, ACL injury is more commonly a non-contact injury, such as a dismount from a layup in basketball. particularly severe form of the contact injury is called the unhappy triad or O'Donaghue's triad, and involves the anterior cruciate ligament, the medial collateral ligament, and the medial meniscus.
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- immune responses against ‘endogenous’ antigens and virally infected targets, whereas HLA class II molecules are involved in the presentation of ‘exogenous’ antigens to T helper cells. The HLA class III region contains
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- Hypogammaglobulinemia is commonly treated with injections of gammaglobulin which has been extracted from donated blood. Hypogammaglobulinemia is a disorder in which the body’s immune system does not make enough or any antibodies. Someone with hypogammaglobulinemia may be more susceptible to viral infections like the cold or flu. Someone with hypogammaglobulinemia often experiences sinusitis problems.
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IPEX syndrome IPEX (immunodysregulation polyendocrinopathy enteropathy X-linked syndrome) is a rare disease linked to the dysfunction of the transcription factor FOXP3, widely considered to be the master regulator of the regulatory T cell lineage. It leads to the dysfunction of regulatory T-cells and the subsequent autoimmunity.
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HLA-B27 Syndromes An HLA disease association is defined as a statistically increased frequency of the HLA haplotype in individuals with the disease compared to the frequency in individuals without the disease. This is expressed as a relative risk. For example, HLA-B27 appears in 80-90% of patients with ankylosing spondylitis.