causes of lymphoproliferative disease
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- The following medical conditions are some of the possible causes of Lymphoproliferative disorders. There are likely to be other possible causes, so ask your doctor about your symptoms. 1  Common variable immunodeficiency. 2  Wiskott-Aldrich syndrome. 3  Ataxia telangiectasia. 4  Severe combined immunodeficiency. 5  AIDS.
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What causes low lymphocytes in the blood? The condition that you are possibly faced with is an infection and is called lymphocytopenia. This simply means that you have a low level of immune system lymphocytes in your blood. This can sometimes occur after a huge infection in which the lymphocytes were used up to destroy the invading pathogens, a result of corticosteroid use, cancer treatments, and, worst of all, HIV infection.
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- Medical conditions such as liver or kidney disease; blood disorders, such as hemophilia, platelet dysfunction, thrombocytopenia, leukemia, and multiple myeloma; connective tissue disorders including scurvy, Marfan's syndrome, and Ehlers-Danlos syndrome may all cause easy bruisability.
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- Mesenteric lymphadenopathy can result from lymphoma, sarcoma, acquired immunodeficiency syndrome (AIDS), tuberculosis, Whipple's disease and post transplant lymphoproliferative disorder (PTLD), of which non Hodgkin's lymphoma is the most common cause.
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Dr. Roach: Low lymphocyte count is cause for concern A partial list of other causes for low lymphocyte count include medications (usually powerful anti-immune-system medicines or chemotherapy), autoimmune diseases such as lupus or rheumatoid arthritis, lymphoma and other cancers, and primary diseases of the immune system, such as aplastic anemia.
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History Edema. 1  Hypoalbuminemia from chronic protein malabsorption or from loss of protein into the intestinal lumen causes peripheral edema. 2  Extensive obstruction of the lymphatic system, as seen in intestinal lymphangiectasia, can cause protein loss. 3  With severe protein depletion, ascites may develop.
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What Causes Lymphocytosis? 1. What is in the differential diagnosis of neutrophilia or neutropenia? 2. What causes eosinophilia? see What Causes Eosinophilia? Related Cases. Disease: Lymphocytosis | Blood and Blood Disorders. Symptom/Presentation: Health Maintenance and Disease Prevention | Rhinitis. Specialty: Hematology | Rhinitis. Age: Toddler. To Learn More
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- The differential diagnosis of lymphocytopenia includes: 1  Infections, acute General acute infections. 2  Immunodeficiency AIDS. 3  Immune Systemic lupus erythematosis. 4  Endocrine ACTH. 5  Lymphatic circulation defects Intestinal lymphangectasia. 6  Medications Corticosteroids. 7  Miscellaneous Renal failure.
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What is a Lymphoproliferative Disorder? In those with a lymphoproliferative disorder, increased lymphocytes in the bloodstream can lead to the enlargement of the lymph nodes and the spleen. Many of these disorders originate from inherited conditions and sometimes are caused by acquired immune system dysfunction.
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Lymphatic disease Lymphedema is the chronic pooling of lymph fluid in the tissue. It usually starts in the feet or lower legs. It's also a side-effect of some surgical procedures. Lymphocytosis. Lymphocytosis is a high lymphocyte count. It can be caused by an infection, blood cancer, lymphoma, or autoimmune disorders that are accompanied by chronic swelling.
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- Abstract. A variety of therapeutic agents may increase the risk of lymphoproliferative disorders/neoplasms. These include those agents used to treat other malignancies (i.e., cytotoxic chemotherapy) and those used to treat or prevent certain diseases (or graft rejection) that alter the immune system. These include lymphoid neoplasms that arise after treatment for other malignancies and a number of distinct lymphoproliferative disorders/neoplasms that develop in the context of therapy used to treat or prevent certain diseases (or graft rejection) that alter the immune system (Table 1). Table 1.
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Meige disease When this fluid builds up abnormally, it causes swelling (lymphedema) in the lower limbs. Meige disease is classified as a primary lymphedema, which means it is a form of lymphedema that is not caused by other health conditions. In Meige disease, the lymphatic system abnormalities are present from birth (congenital), although the swelling is not usually apparent until puberty.
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Lymphoma The exact causes of lymphoma are not known. Several factors have been linked to an increased risk of developing lymphoma, but it is unclear what role they play in the actual development of lymphoma. These risk factors include the following: Age: Generally, the risk of NHL increases with advancing age.
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- Milroy's disease (congenital lymphedema). This disorder begins in infancy and causes lymph nodes to form abnormally. Meige's disease (lymphedema praecox). This disorder often causes lymphedema around puberty or during pregnancy, though it can occur later, until age 35.
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- Lymphatic filariasis, also known as elephantiasis tropica, is caused by parasitic worms of the Filarioidea type.Many cases of the disease have no symptoms. Some however, develop large amounts of swelling of the arms, legs, or genitals. The skin may also become thicker, and pain may occur.ymphatic filariasis, also known as elephantiasis tropica, is caused by parasitic worms of the Filarioidea type.
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lymphocytopenia People at highest risk for lymphocytopenia have one of the diseases, conditions, or factors that can cause a low lymphocyte count. This includes people who have:eople at highest risk for lymphocytopenia have one of the diseases, conditions, or factors that can cause a low lymphocyte count. This includes people who have:
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Hilum Anatomy and Abnormalities 1 Sarcoidosis is the most common cause of bilateral hilar lymph node enlargement.  Other infections such as mycobacteria, viral infections such as infectious mononucleosis, berylliosis, tularemia, histoplasmosis, and coccidiomycosis.
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ASH Home ASH Store ASH AcademyMy Account Sign In This disorder is typically found in young to middle-aged women who smoke, have a high association with HLA-DR7, and show a longstanding lymphocytosis that is polyclonal by flow cytometry, but some genetic abnormalities have been documented. 13 In addition, large granular lymphocytosis, an increased number of similar appearing large granular lymphocytes (a normal component of the blood), may be seen with viral infections, malignancy, after BM transplantation, and after chemotherapy .
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Myeloproliferative Diseases Chronic myeloproliferative diseases. Chronic myeloproliferative diseases are caused by an overabundance of differentiated bone marrow cells that result in the accumulation of erythrocytes, granulocytes, monocytes or platelets. Polycythemia Vera. This condition is marked by an overproduction of RBCs.
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HemophagocyticLymphohistiocytosisHEMOâ¢PHAâ¢GOâ¢CYâ¢TIC LYMPHâ¢Oâ¢HISâ¢TIâ¢Oâ¢CYâ¢TOâ¢SIS HLH has traditionally been divided into genetic forms (Familial HLH or FHLH) or acquired forms which may be associated with infections, autoimmune conditions or cancer. To date, 9 genetic causes of FHLH have been discovered, accounting for about 50% of childhood HLH cases in the U.S.A.
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- It is caused by: 1  Lymphoid tumours. 2  Prolymphocytic leukaemia (PLL) 3  Hairy cell leukaemia (HCL) 4  Lymphomas with leukaemic expression. 5  Large granular lymphocytic leukaemia. 6  Acute lymphoblastic leukaemia (ALL) and chronic lymphocytic leukaemia (CLL).
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- The following medical conditions are some of the possible causes of Lymphoproliferative disorders. There are likely to be other possible causes, so ask your doctor about your symptoms. 1  Common variable immunodeficiency. 2  Wiskott-Aldrich syndrome.
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Lymphogranuloma venereum Written By: Lymphogranuloma venereum, also called lymphogranuloma inguinale or Nicolas-Favre disease, infection of lymph vessels and lymph nodes by the microorganism Chlamydia trachomatis. Like chlamydia, which is also a disease caused by C. trachomatis, lymphogranuloma venereum is usually sexually transmitted. The disease produces swollen lymph nodes, ulcerations, enlargement of genital organs, and rectal stricture. Lymphogranuloma venereum occurs throughout most of the world, especially in tropical and subtropical areas.