which statins give the most muscle pain
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Overview Muscle breakdown. Rhabdomyolysis, or the breakdown of muscle tissue, is a rare side effect of statins that can also cause muscle pain. This disease can cause life-threatening muscle damage. In addition to severe muscle pain, rhabdomyolysis can lead to liver damage, kidney failure, and, in rare cases, death.
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Statin side effects: Weigh the benefits and risks Muscle pain and damage. One of the most common complaints of people taking statins is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult.
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- Muscle pain can often be treated, and might signal a more serious health issue. By Adam Voiland. + More. Most people who take statins suffer no side effects from the cholesterol-lowering drugs. A small but significant number, however, develop mild to crushing muscle pain. In rare cases, the drugs can lead to permanent muscle damage, kidney problems, and death.
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- Statins may affect certain enzymes present in muscle cells that handle muscle growth. This may cause the muscle aches. If you experience muscle pain as a result of taking statins, immediately let your doctor know. There are some things that your doctor can do to help. Your doctor may start by taking you off of the drug for a while to see how your body responds. Your muscle pain could be due to the statin, or it might simply be a byproduct of getting older. There are several statin drug options, so your doctor may prescribe a different drug and see if you have a better reaction.
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Why Do Statins Cause Muscle Pain? A Side Effect of Statins is Muscle Pain. About 5 to 10 percent of patients taking statins experience clinically significant side effects, which is higher than original reports. Symptoms may appear within the first six months of treatment or appear after several years.
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Lipitor and Muscle Pain Lipitor and Muscle Pain. People may experience many different side effects while taking Lipitor, and muscle pain is one of them. In research studies, muscle pain occurred in up to 5.6 percent of people taking the drug. Most people experience no other related symptoms; however, in rare cases, muscle pain could be the sign of serious problems.
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Paget's Disease in the Spine: Not So Easy to Recognize Statin Myotosis: A Not-So-Rare Cause of Muscle Pain. It is not uncommon for patients with muscle pain to end up in a chiropractic office, either by referral from another clinician or by self-referral. There are many conditions including trauma that are associated with inflammation of muscles.
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Managing Muscle Pain Related to Cholesterol Medication Medications called “statins” are the most commonly prescribed drugs used to reduce cholesterol. Some examples of statin medications are Lipitor® (atorvastatin), Pravachol® (pravastatin), Zocor® (simvastatin), Livalo® (pitavastatin) and Crestor® (rosuvastatin). Unfortunately, some people may experience muscle pain or weakness while taking statins. The pain may be minor such as soreness or stiffness. However, muscle pain, particularly if severe and accompanied by dark-colored urine, may be an indication of a more serious, life-threatening problem called rhabdomyolysis.
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Side Effects of Statins When taken at high doses, simvastatin may be more likely to cause muscle pain than other statins. The more common side effects of taking higher doses of this drug also include: dizziness ; fast or irregular heartbeat ; Pravastatin . People taking pravastatin have reported fewer muscle aches and other side effects.
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Side effects Muscle effects. Statins can occasionally cause muscle inflammation (swelling) and damage. Speak to your doctor if you experience muscle pain, tenderness or weakness that cannot be explained (for example, pain that is not due to physical work).tatins can occasionally cause muscle inflammation (swelling) and damage. Speak to your doctor if you experience muscle pain, tenderness or weakness that cannot be explained (for example, pain that is not due to physical work).
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- Muscle pain and damage The most common statin side effect is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult.ost people taking statins will take them for the rest of their lives unless they can achieve normal cholesterol levels through diet, exercise, weight loss and nutritional supplements. This can make statin side effects more difficult to manage.
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Muscle problems caused by statins: Can a genetic test reveal your risk? But here’s the rub: muscle problems can range from mild to serious, and the terms experts use to describe them can be confusing. The StatinSmart website says 29% of people who take a statin develop “statin-induced myopathy,” which they define as muscle aches, pains, weakness, or cramps.
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What to do when you suspect a statin causes muscle pain In any event, your doctor was being pretty aggressive in trying to prevent a first heart attack, which I can understand. Muscle aches on statin drugs like Lipitor are common. Sometimes, but not always, they can cause muscle inflammation as well, with evidence of muscle breakdown in the blood. It's important to emphasize that not all cases of muscle aches due to statins have abnormal blood results. If the muscle aches stop while off the statin, it is likely that the statin caused them.
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Rhabdomyolysis from statins: What's the risk? Although mild muscle pain is a relatively common side effect of statins, some people who take statin medications to lower their cholesterol may have severe muscle pain. This intense pain may be a symptom of rhabdomyolysis (rab-doe-my-OL-ih-sis), a rare condition that causes muscle cells to break down.The most common signs and symptoms of rhabdomyolysis include:The higher the dose of statins, the higher the risk of rhabdomyolysis becomes. The risk also increases if certain drugs — including ...
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Statin Side effects of statins include muscle pain, increased risk of diabetes mellitus, and abnormalities in liver enzyme tests. Additionally, they have rare but severe adverse effects, particularly muscle damage. They inhibit the enzyme HMG-CoA reductase which plays a central role in the production of cholesterol.
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How Statin Drugs Wreck Your Muscles Statins have been known to cause muscle weakness and pain, but no one knew exactly why. This latest study sheds some valuable information on the subject and adds to your arsenal when discussing whether or not you really need to be taking a statin drug with your doctor.
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9 Types of Medications That Can Lead to Chronic Fatigue The top-selling statins are atorvastatin (Lipitor), rosuvastatin (Crestor) and simvastatin (Zocor); the top-selling fibrate is fenofibrate (Tricor). How they can cause fatigue: Studies show that statins stop the production of satellite cells in the muscle, stopping muscle growth. Some researchers have also suggested that statins interfere with the production of energy at the cellular level in the same way that they interfere with the production of cholesterol.
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Dangers of Statin Drugs: What You Havenât Been Told About Popular Cholesterol-Lowering Medicines By the way, other cholesterol-lowering agents besides statin drugs can cause joint pain and muscle weakness. A report in Southern Medical Journal described muscle pains and weakness in a man who took Chinese red rice, an herbal preparation that lowers cholesterol.
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- A: Crestor (rosuvastatin) is a statin medication used to treat high cholesterol. The most common side effects with Crestor are muscle pain, constipation and sore throat. Other side effects with Crestor include joint pain, and weakness This is not a complete list of the side effects associated with Crestor.ore serious side effects include problems with muscles and the liver. Symptoms that indicate serious side effects from Crestor include muscle weakness, tenderness, and pain; dark-colored urine; unexplained tiredness; and stomach pain.
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Statin However, like most medications, there are potential side effects. Side effects of statins include: 1  muscle pain as the most common side effect.  an increase in production of enzymes in the liver as an occasional side effect.
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Statins and Myoglobin: How Muscle Pain and Weakness Progress to Heart, Lung and Kidney Failure 3. Statins, Muscle Pain and Weakness, and Rhabdomyolysis. Muscle cells have tremendous energy needs, particularly if the person has been put on an exercise regimen as part of their treatment program. The heart, in particular, never rests. It has to keep on beating 24x7 at the rate of at least once every second.
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Statin Drugs Muscle Weakness Can Be a Sign of More Problems Can Be a Sign of More Problems. The problem of Statin Drugs Muscle Weakness and/or muscle pain is a condition that is technically known as 'Statin Induced Myopathy' and occurs in a certain percentage of people that take the Cholesterol lowering 'Statin medications'.f it is not, then the risk of side effects such as Statin Drugs Muscle Weakness, liver problems, muscle pain, muscle damage, poor memory and other Statin Side Effects may not be worth such risks.
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Is there any evidence that different statins are more or less likely to cause muscle pain? As the authors state, One of the most frequently discussed side effects of statins is myalgia...In this analysis...there was a nonsignificant trend toward lower reports of myalgia in statin-treated patients compared with placebo-treated patients...This finding is difficult to reconcile with the observation in clinical practice of the association with myalgias but suggests that the risk was not substantial in patients enrolled in these trials.
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Statin side effects: Weigh the benefits and risks What causes statin side effects? It's unclear what causes statin side effects, especially muscle pain. Statins work by slowing your body's production of cholesterol. Your body produces all the cholesterol it needs by digesting food and producing new cells on its own.
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- If therapy is stopped, these benefits will be lost and cholesterol levels will return to pretreatment levels. Statins have several effects on muscle. They can cause muscle and leg cramps, myalgia (muscle pain), myositis (muscle inflammation) and rhabdomyolysis (Muscle breakdown). Rhabdomyolysis is a serious condition that often starts as muscle pain and may result ultimately in kidney failure.