what is are causes of als
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- Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease that causes muscle weakness and gradually impacts on the functioning of the body, leading to eventual death. It is also referred to as motor neuron disease or Lou Gehrig's disease, named after the famous baseball player who had the condition.
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Overview Amyotrophic lateral sclerosis (a-mi-o-TROE-fik LAT-ur-ul skluh-ROE-sis), or ALS, is a nervous system (neurological) disease that causes muscle weakness and impacts physical function. ALS is often called Lou Gehrig's disease, after the famous baseball player who was diagnosed with it.ALS is a type of motor neuron disease that causes nerve cells to gradually break down and die. In the United States, ALS is sometimes called motor neuron disease. In most cases, doctors don't know why ALS occurs.A small number of cases are inherited.ALS often begins with muscle twitching and weakness in an arm or leg, or sometimes with slurring of speech.n the United States, ALS is sometimes called motor neuron disease. In most cases, doctors don't know why ALS occurs. A small number of cases are inherited. ALS often begins with muscle twitching and weakness in an arm or leg, or sometimes with slurring of speech.
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- Wednesday 1 February 2017 13.08 EST Last modified on Tuesday 14 March 2017 18.42 EDT. A CNN editor has filed a lawsuit against Trump’s travel ban, after being detained at Atlanta’s airport over the weekend because of the controversial executive order. Mohammed Tawfeeq, an Iraqi citizen and US green card holder since 2013, was returning from Iraq on Sunday following a CNN assignment in his role as manager for CNN’s international desk.
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- In the vast majority of ALS cases, no specific cause of the disease can be identified. In about 5 percent of ALS cases, though, the disease is inherited. These familial cases are due to mutations in a number of genes.At this time, researchers have only been able to identify about one-third of the gene mutations responsible for ALS.ost cases of amyotrophic lateral sclerosis (ALS) are not familial and do not run in families. In a minority of ALS cases, though, the disease may be inherited and occur in multiple family members.
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Genetics C9ORF72. This gene, discovered in 2011, is the most common genetic cause of ALS. (Its name refers to the position of an “open reading frame” on chromosome 9). Mutations in this gene account for between 25% and 40% of all familial ALS cases (depending on the population), and also approximately 4% to 6% of sporadic cases.As noted above, these apparently sporadic cases are in fact genetic.utations in SOD1 were first described in 1993, and SOD1 was the first gene known for ALS. It accounts for about 10% of familial ALS, or 1.5% to 2% of all ALS. It is inherited in a dominant manner. How SOD1 mutations cause ALS is unknown.
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- Amyotrophic Lateral Sclerosis (ALS), also commonly known as Lou Gehrig’s Disease, is a progressive neurodegenerative disease that causes muscle weakness, paralysis, and ultimately, respiratory failure. You’ve still got lots more to learn. But before you do, we’d like to ask for your help.
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About 'Get Cured' Logo 1 Dr. B. P. Pranav was ordained as Sramanera with the name of Ven. 2  Sanghapala and was leading a monastic life for the period from 10.07.2009 to 22.07.2009 under the preceptorship of Dr. Bhikkhu Bodhipala the Vibarathipathy, Dharmavijaya Maha Vihara Trust, Kuthadampatti 625218. Dr. B.P. Pranav is a secretary for A tma G nana Y oga S abha of Dr. Pandit G. Kanniah Yogi since 2011. 2  Dr. B.P. Pranav is a Research and Development Director of O rganization for R esearch on D elta P hysics (ORDP) since 2013.
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Lou Gehrig's Disease (ALS) Directory Lou Gehrig's Disease, or amyotrophic lateral sclerosis (ALS), is an incurable neurological disease in which a person loses the ability to move their arms, legs, and other muscles, including those used to eat and breathe. It occurs when nerve cells that control muscles for voluntary movement die.ollow the links below to find WebMD's comprehensive coverage about how Lou Gehrig's Disease (ALS) develops, what the symptoms are, how to treat it, and much more.
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What Is ALS? What Are the Types and Causes? Eventually, people with ALS lose control of their diaphragm, the muscles in the chest that help you breathe. Then they can't breathe on their own and will need to be on a breathing machine. The loss of breathing causes many people with ALS to die within 3 to 5 years after they're diagnosed. Yet some people can live more than 10 years with the disease. People with ALS can still think and learn. They have all of their senses -- sight, smell, hearing, taste, and touch.
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The Effects Of ALS â Lou Gehrigâs Disease ALS affects only motor neurons the nerve cells that originate in the brain or the spinal cord and run to muscle cells to stimulate them to contract. Brain cells that are involved in thought, vision, hearing and other brain functions are not affected.
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All about amyotrophic lateral sclerosis (ALS) ALS, or Lou Gehrig's disease, is the most common type of motor neuron disease. Learn about the other types, and how they can affect your muscles. Skip to main content
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Smooth Muscle amyotrophic lateral sclerosis. At least 200 mutations in the SOD1 gene have been found to cause amyotrophic lateral sclerosis (ALS), a condition characterized by progressive muscle weakness, a loss of muscle mass, and an inability to control movement.
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What are Muscle disorders? Amyotrophic lateral sclerosis (ALS) is a disease that breaks down tissues in the nervous system (a neurodegenerative disease) of unknown cause that affects the nerves responsible for movement. It is also known as motor neuron disease and Lou Gehrig's disease, after the baseball player whose career it ended.
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What Is ALS? What Are the Types and Causes? ALS is short for amyotrophic lateral sclerosis. You might also have heard it called Lou Gehrig's disease, after the baseball player who was diagnosed with it in the 1930s. A French doctor named Jean-Martin Charcot discovered the condition in 1869. ALS is a progressive disease, which means it gets worse over time. It affects nerves in your brain and spinal cord that control your muscles. As your muscles get weaker, it gets harder for you to walk, talk, eat, and breathe.
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Amyotrophic Lateral Sclerosis (ALS) Early Symptoms, Causes, and Prognosis ALS belongs to a wider group of disorders known as motor neuron diseases, which are caused by gradual deterioration (degeneration) and death of motor neurons. Motor neurons are nerve cells that extend from the brain to the spinal cord and to muscles throughout the body.
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Amyotrophic Lateral Sclerosis (ALS) Amyotrophic lateral sclerosis (ALS) is often referred to as Lou Gehrig's Disease and is named for a famous baseball player who had the disease. It is a disease that affects the nerve cells in the spine and brain and causes your neurons (which transmit impulses from your spinal cord to your muscles.
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James A. Haley Veteransâ Hospital - Tampa, Florida Amyotrophic lateral sclerosis or ALS is a disease of nerves in the brain and spinal cord that allow you to control your muscles (motor neurons). There is damage to the motor neurons which causes muscle weakness and loss of muscle (atrophy). ALS can affect any voluntary muscle group.
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Causes of ALS Still, for the majority of ALS cases, we do not know what causes the disease. Researchers haven’t been idle, however, and several attractive theories exist on what could cause or contribute to the death of motor neurons in ALS. Laboratory scientists are focusing on these pathogenic theories.
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- Sporadic and Familial ALS. Most cases of ALS are “sporadic,” meaning they are due to no known cause. Approximately 5-10% of cases are due to known genetic mutations. In most of those cases, another family member also has ALS or a related disease (see C9ORF72 below).9ORF72. This gene, discovered in 2011, is the most common genetic cause of ALS. (Its name refers to the position of an “open reading frame” on chromosome 9). Mutations in this gene account for between 25% and 40% of all familial ALS cases (depending on the population), and also approximately 4% to 6% of sporadic cases.
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- Amyotrophic Lateral Sclerosis ». Amyotrophic lateral sclerosis (ALS) is a disease of unknown cause characterized by slowly progressive degeneration of upper motor neurons (UMNs) and lower motor neurons (LMNs). Read More on Medscape Reference ».
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Amyotrophic lateral sclerosis Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) and Lou Gehrig's disease, is a specific disease that causes the death of neurons which control voluntary muscles. Some also use the term motor neuron disease for a group of conditions of which ALS is the most common. ALS is characterized by stiff muscles, muscle twitching, and gradually worsening weakness due to muscles decreasing in size.
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Common Cause of Lou Gehrig's Disease Found Aug. 22, 2011 -- Researchers from Northwestern University are reporting a major breakthrough in understanding of the cause of amyotrophic lateral sclerosis (ALS), the fatal disease also known as Lou Gehrig’s disease.nly about one in 10 ALS patients have the inherited form of the disease. Because no cause had been identified in people without a family history, researchers have not been certain that different forms of ALS were actually the same disease.
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About Familial ALS What we do know is that in about 2 in 10 families with ALS, the disease is caused by a change in the superoxide dismutase, or SOD1, gene. Genetic changes in genes such as FUS and TDP-43 are the cause of ALS in an even smaller number of families with ALS, each accounting for approximately 1 in 20-25 families.
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Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosis (ALS), also referred to as Lou Gehrig's disease is a disease of the motor nerve cells in the brain and spinal cord. ALS is caused by progressive loss of motor nerves in these areas and affects approximately 1 out of 100,000 people.
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What causes ALS? Although the cause of ALS is unknown, heredity plays a role in 5% to 10% of cases. A fraction of all cases of familial ALS (that is, inherited ALS) is believed to be caused by a defective gene that prevents the body from producing a normal amount of an enzyme called superoxide dismutase.
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- Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive, neurodegenerative disorder that causes muscle weakness. It is incurable and eventually fatal.