define hox genes in biology
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- Hox gene. n. Any of a group of homeobox genes that exist as clusters in animals, especially in vertebrates, and determine the identity and locations of body parts along the anterior-posterior body axis in a developing fetus or larva. [From h(omeob)ox .].
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- EPH. A gene on chromosome 7q32-q36 that encodes a member of the ephrin-A receptor subfamily of receptor tyrosine kinases, which promiscuously bind membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signalling into neighbouring cells. gene on chromosome 7q32-q36 that encodes a member of the ephrin-A receptor subfamily of receptor tyrosine kinases, which promiscuously bind membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signalling into neighbouring cells.
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Aprataxin Aprataxin is a protein that in humans is encoded by the APTX gene. This gene encodes a member of the histidine triad superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants
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chromosomes & human inheritance notes Besides genes that determine sex, sex chromosomes carry many genes for traits unrelated to sex. X-linked gene is any gene located on the X chromosome that are missing on the Y chromosome. X-linked alleles are designated as superscripts to X chromosome. Newly discovered mutant male fruit fly had white eyes.
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- Hox gene. noun. Any of a group of homeobox genes that exist as clusters in animals, especially in vertebrates, and determine the identity and locations of body parts along the anterior-posterior body axis in a developing fetus or larva. From h(omeob)ox.
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- Hox gene. n. Any of a group of homeobox genes that exist as clusters in animals, especially in vertebrates, and determine the identity and locations of body parts along the anterior-posterior body axis in a developing fetus or larva. [From h(omeob)ox 1  .]. Facebook.
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- The growth arrest homeobox gene hereinafter referred to as the Gax gene and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.
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Geneâenvironment interaction Gene–environment interaction (or genotype–environment interaction or G×E) is when two different genotypes respond to environmental variation in different ways. A norm of reaction is a graph that shows the relationship between genes and environmental factors when phenotypic differences are continuous. They can help illustrate GxE interactions. When the norm of reaction is not parallel, as shown in the figure below, there is a gene by environment interaction.
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- The Bax protein is a promoter of apoptosis The p53 gene is activated by DNA damage It is thought toapoptosis. The p53 gene is activated by DNA damage. It is thought to be important in normal cells to slow the cell cycle when DNA is damaged to permit DNA repair before the DNA is replicated.
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- Overexpression of Hox transcript antisense intergenic RNA (HOTAIR), a long non-coding RNA (lncRNA), is associated with cancer cell proliferation, invasion, progression, and metastasis as well as poor survival in a variety of human cancers including breast cancer (BC).
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The 9 Phylums A type of embryonic development in deuterostomes, in which each cell produced by early cleavage divisions retains the capacity to develop into a complete embryo. Hox Genes series of genes that controls the organs and tissues that develop in various parts of an embryo.
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Intro to Cell Biology - Exam 4 (chapters 13, 1 Genotype: the genetic makeup of an organism, or the versions of a gene that an organism has. 2  Heterozygous: having two different versions of a gene. 3  Homozygous: having two identical versions of a gene.
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Hox gene Homeobox (Hox) gene expression in Drosophila melanogaster Drosophila melanogaster is an important model for understanding body plan generation and evolution. The general principles of Hox gene function and logic elucidated in flies will apply to all bilaterian organisms, including humans.
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- Genome Analyzer: PhiX control lane. The phi X 174 (phiX) bacteriophage genome is a circular DNA molecule of 5386 bases. A PhiX library is used as a control lane to validate the quality of each run. The PhiX lane is also used as reference by the GAPipeline base-calling software. The sequence files are provided under solexa fast-q format: @HWI-EAS210R_0001:4:10:890:1010#0/1.
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Chris Lewis at the U of S Defining Homolog, Ortholog and Paralog. Homolog: A gene related to a second gene by descent from a common ancestral DNA sequence. The term homolog may apply to the relationship between genes separated by speciation (ortholog), OR to the relationship betwen genes originating via genetic duplication (see paralog). Ortholog: Orthologs are genes in different species that have evolved from a common ancestral gene via speciation (1).
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HEXA Gene Therapies for Tay-Sachs The HEXA gene is a protein encoding gene that codes for the lysosomal enzyme beta-hexosaminidase. This enzyme, combined with the GM2 activator protein, is responsible for the breakdown of ganglioside GM2 within the lysosome.
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genetic testing Sex-linked disorder. A disorder caused by a gene located on a sex chromosome, usually the X chromosome. Mentioned in: Genetic Testing. 1  Facebook. 2  Twitter.
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BAX BAX expression is regulated by p53, the tumour suppressor, and is involved in p53-mediated apoptosis. Bax. A 21-kD protein encoded by BAX, located on chromosome 19q13.3-q13.4, which has significant homology with Bcl-2, the apoptosis repressor, with which it forms a heterodimer.Overexpression of Bax compared to Bcl-2 signifies apoptosis.ax. A 21-kD protein encoded by BAX, located on chromosome 19q13.3-q13.4, which has significant homology with Bcl-2, the apoptosis repressor, with which it forms a heterodimer. Overexpression of Bax compared to Bcl-2 signifies apoptosis.
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Learning About Turner Syndrome Turner syndrome is a chromosomal condition related to the X chromosome. Researchers have not yet determined which genes on the X chromosome are responsible for most signs and symptoms of Turner syndrome. They have, however, identified one gene called SHOX that is important for bone development and growth.
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Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies Treatment (PDQÂ®)âHealth Professional Version NUP98/JARID1A is associated with a high expression of HOXA and HOXB genes, indicative of a stem cell phenotype, similar to what we reported for NUP98/NSD1. With exception of the RBM15/MKL1-translocated patients, non-Down syndrome AMKL in general has a poor outcome, including the NUP98/JARID1A cases.
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Absinthe It is an anise-flavoured spirit derived from botanicals, including the flowers and leaves of Artemisia absinthium (grand wormwood), together with green anise, sweet fennel, and other medicinal and culinary herbs. Absinthe traditionally has a natural green colour but may also be colourless.he French word absinthe can refer either to the alcoholic beverage or, less commonly, to the actual wormwood plant, with grande absinthe being Artemisia absinthium, and petite absinthe being Artemisia pontica.
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Hox gene Segmentation involves such processes as morphogenesis (differentiation of precursor cells into their terminal specialized cells), the tight association of groups of cells with similar fates, the sculpting of structures and segment boundaries via programmed cell death, and the movement of cells from where they are first born to where they will ultimately function, so it is not surprising that the target genes of Hox genes promote cell division, cell adhesion, apoptosis, and cell migration.
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holo-, hol- holo-, hol-. (Greek: whole, entire, complete) Pertaining to genes that are carried by the Y chromosomes: The holandric genes are produced only through the paternal, or male, and never by the female.. Genes that males have from the Y chromosomes: The Y-linked genes can only be transmitted from a father to his son..
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Developmental biology: Hox gene variation and evolution Developmental biology: Hox gene variation and evolution. Axel Meyer. Both developmental and evolutionary biologists try to explain patterns in the diversity among organisms, and the Hox genes encode a class of transcription factors that have provided ample material for such discussions.