causes of itp
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Overview Immune thrombocytopenia. This type is caused by autoimmune diseases, such as lupus and rheumatoid arthritis. The body's immune system mistakenly attacks and destroys platelets. If the exact cause of this condition isn't known, it's called idiopathic thrombocytopenic purpura.
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Immune thrombocytopenic purpura Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia. It causes a characteristic purpuric rash and an increased tendency to bleed.
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- The initial treatment and prognosis of ITP in adults is reviewed here. Second--line therapies for adults who require additional treatment, and the management of ITP in children, who have a different clinical course from adults, are discussed separately. ●Primary ITP – Primary ITP is acquired thrombocytopenia due to autoimmune platelet destruction, not triggered by an associated condition. (See Immune thrombocytopenia (ITP) in adults: Clinical manifestations and diagnosis.) Subscribers log in here.
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- Bleeding in the brain as a result of ITP is very rare, but can be life threatening if it occurs. In most cases, an autoimmune response is thought to cause ITP. Normally, your immune system helps your body fight off infections and diseases. But if you have ITP, your immune system attacks and destroys its own platelets. The reason why this happens isn't known.
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Thrombocytopenia and ITP Thrombocytopenia can run in families, but you can also get it from many medical conditions. Treating the medical condition may improve ITP. Your body might have fewer platelets because of these causes: Infections. Viral infections, including chickenpox, parvovirus, hepatitis C, Epstein-Barr, and HIV.
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Idiopathic Thrombocytopenic Purpura (ITP) ITP stands for idiopathic thrombocytopenic purpura. Idiopathic means that the cause of the condition is unknown. Thrombocytopenic means the blood doesn't have enough platelets (platelets are also called thrombocytes). Purpura means a person has excessive bruising.
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What is idiopathic thrombocytopenic purpura (ITP)? ITP is a blood disorder characterized by an abnormal decrease in the number of platelets in the blood. Platelets are cells in the blood that help stop bleeding. A decrease in platelets can result in easy bruising, bleeding gums, and internal bleeding.
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Immune Thrombocytopenia  (ITP) Immune thrombocytopenia (ITP) may not cause any signs or symptoms. However, ITP can cause bleeding inside the body (internal bleeding) or underneath or from the skin (external bleeding). Signs of bleeding may include: 1  Bruising or purplish areas on the skin or mucous membranes (such as in the mouth).n ITP, the blood doesn't clot as it should. This is due to a low number of blood cell fragments called platelets (PLATE-lets) or thrombocytes (THROM-bo-sites). Platelets are made in your bone marrow along with other kinds of blood cells.
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Henoch-Schonlein Purpura (HSP) Causes and Risk Factors for Henoch-Schonlein Purpura. The exact cause of HSP is not known. The body's immune system is believed to play a role in targeting the blood vessels involved. An abnormal immune response to an infection may be a factor in many cases.enoch-Schonlein purpura (HSP) is a disease involving inflammation of small blood vessels. It most commonly occurs in children.
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Immune thrombocytopenic purpura ITP is diagnosed by a low platelet count in a complete blood count (a common blood test). However, since the diagnosis depends on the exclusion of other causes of a low platelet count, additional investigations (such as a bone marrow biopsy) may be necessary in some cases.
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What is Immune Thrombocytopenia? By Amber Yates, MD - Reviewed by a board-certified physician. Definition. Immune thrombocytopenia (ITP), formerly called idiopathic thrombocytopenic purpura, is a condition where your body’s immune system attacks and destroys your platelets causing low platelet counts (thrombocytopenia) which may result in bleeding.
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What is Immune Thrombocytopenia? ITP is a result of antibodies that attach to the platelets. The spleen recognizes these antibodies and destroys the platelets. Sometimes doctors are unable to find a cause for the ITP. Viruses: In children, ITP is often triggered by a viral infection.
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Lichen planus The exact cause of lichen planus is unknown. It may be related to an allergic or immune reaction. Risks for the condition include: Exposure to medicines, dyes, and other chemicals (including gold, antibiotics, arsenic, iodides, chloroquine, quinacrine, quinide, phenothiazines, and diuretics)
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- In the majority of cases, the pox marks heal up without scarring. Being an airborne disease, chickenpox spreads easily and rapidly through sneezing and coughing, as well as direct contact with the secretions from the blisters.
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Family Health Guide These include idiopathic thrombocytopenia purpura (ITP), a blood-clotting disorder that may follow a viral illness, or meningococcal disease, which can cause meningitis, a bacterial infection of the lining between the brain and the skull, or meningococcemia, a widespread bacterial infection of the bloodstream.
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Henoch-SchÃ¶nlein Purpura HSP is caused when a person's immune system doesn't fight an infection like it's supposed to. It occurs most often in the spring, usually after an upper respiratory infection, like a cold. HSP occurs most often in children from two to 11 years of age, but it can occur in anyone. Its exact cause is unknown. It might be triggered by bacterial or viral infections, medicines, insect bites, vaccinations or exposure to chemicals or cold weather.
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Alone we are rare. Together we are strong.â¥ Donate Today Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by the abnormally low levels of blood cells called platelets, otherwise referred to as thrombocytopenia.
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Immune Thrombocytopenic Purpura (ITP) At very low platelet levels, ITP can cause different symptoms, depending on the type of ITP. Acute ITP — Symptoms usually begin abruptly. In children, the trigger can be a viral infection, with ITP symptoms appearing one to three weeks after the infection resolves.
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About ITP 1 TPO, a protein made by the liver, controls the production of platelets.11.  When the body functions normally, too few platelets in the bloodstream cause more TPO to be sent to bone marrow cells—boosting platelet production.11 For people with ITP, the TPO level is too low relative to the level of platelets.
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Immune Thrombocytopenia  (ITP) If an autoimmune disease destroys the body's platelets, thrombocytopenia can occur. One example of this type of autoimmune disease is immune thrombocytopenia (ITP). ITP is a bleeding disorder in which the blood doesn't clot as it should. An autoimmune response is thought to cause most cases of ITP.
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- If you have ITP, your treatment depends on how severe a case you have. If it's mild, you may only need to get regular checks of your platelet levels. When you do need treatment, the goal is to get your platelet count to a level that's high enough to prevent serious bleeding in the gut or brain.
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Diagnosis People with mild idiopathic thrombocytopenic purpura may need nothing more than regular monitoring and platelet checks. Children usually improve without treatment. Most adults with ITP will eventually need treatment, as the condition often becomes severe or long-term (chronic) ITP. Treatment may include a number of approaches, such as medications to boost your platelet count or surgery to remove your spleen (splenectomy).
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Diagnosis Your doctor may prescribe one or more of the following medications to treat ITP: 1  Drugs that suppress your immune system. 2  Injections to increase your blood count. 3  Drugs that boost platelet production.  Other immune-suppressing drugs.
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What Are the Common Causes and Treatments for Itching? The causes of itching can be divided into localized and generalized. Areas of itching that are localized on one part of the body are more likely caused by a problem of the skin. The area of the body that itches may give a clue as to the cause of the itch. For example, itching of the scalp is most likely due to seborrheic dermatitis (dandruff), atopic dermatitis, contact dermatitis, psoriasis, or head lice. Generalized itching may be due to various skin diseases, as well as systemic disease.
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Lichen planus Causes. Lichen planus occurs when your immune system mistakenly attacks cells of the skin or mucous membranes. No one knows the exact cause of this abnormal immune response. The condition isn't contagious. In some people, certain factors, such as those below, may trigger lichen planus. Hepatitis C infection; Flu vaccine
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Thrombocytopenia and ITP Causes. Although doctors don't know what causes ITP, they know that it happens when your immune system -- your body's defense against disease -- doesn't work right. Your antibodies, which are supposed to attack infections, instead mistakenly destroy your blood platelets.
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- In general, the main causes of increased CRP and other markers of inflammation are: 1  burns, 2  trauma, 3  infections, 4  inflammation, 5  active inflammatory arthritis, and. 6  certain cancers.