what is ipilimumab
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NCI Dictionary of Cancer Terms It is a type of monoclonal antibody. Monoclonal antibodies are a type of biological therapy. Ipilimumab is a treatment for melanoma that is advanced. Advanced melanoma means that the melanoma has spread deeply into the skin and cannot be removed or it has spread to another part of the body.You may also have ipilimumab as part of clinical trials for other types of cancer including advanced prostate cancer.ou have ipilimumab into your bloodstream (intravenously). You can have it through a thin, short tube (a cannula) put into a vein in your arm each time you have treatment. Or you may have it through a central line, a portacath or a PICC line.
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Basal Cell Carcinoma Imiquimod Imiquimod (Aldara) is an immune system booster available in a 5% cream that is FDA-approved for the treatment of genital warts, actinic keratoses (pre-cancers of the skin) and superficial basal cell carcinomas (common skin cancers).
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Formulary Drug Review: Ipilimumab (Yervoy) Ipilimumab was dosed at 3 mg/kg IV every 3 weeks for a total of 4 treatments with the vaccine administered immediately after each ipilimumab infusion. The median overall survival at 20 months was 10, 10.1, or 6.4 months for patients treated with the combination, ipilimumab alone, or gp100 alone, respectively.
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Imbruvica This medication is used to treat certain cancers (such as mantle cell lymphoma, chronic lymphocytic leukemia, Waldenstrom's macroglobulinemia). Ibrutinib belongs to a class of drugs known as kinase inhibitors. It works by slowing or stopping the growth of cancer cells.
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COMPANION ARTICLES Recently, ipilimumab was approved by the US Food and Drug Administration for the treatment of metastatic melanoma. We review the literature on managing the adverse effects and kinetics of tumor regression with ipilimumab and provide guidelines on their management.During treatment with these antibodies, a unique set of adverse effects may occur, called immune-related adverse events (irAEs).bstract. Monoclonal antibodies directed against the immune checkpoint protein cytotoxic T-lymphocyte antigen-4 (CTLA-4; CD152)—ipilimumab and tremelimumab—have been investigated in metastatic melanoma and other cancers and have shown promising results.
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- Rasburicase (Fasturtec ®) Rasburicase is a drug given before and during chemotherapy for some types of leukaemia and lymphoma. It can help prevent or reduce a side effect of chemotherapy called tumour lysis syndrome. This information describes rasbiricase, how it’s given and some of its possible side effects.
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- What regorafenib is. Regorafenib is also called by its brand name Stivarga. It is a treatment for. 1  Bowel cancer that has spread to other parts of the body – when other treatments are no longer working or are unsuitable. 2  Gastro intestinal stromal cancer (GIST) – a rare type of soft tissue sarcoma of the stomach or intestines.
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Nivolumab It is used as a first line treatment for inoperable or metastatic melanoma in combination with ipilimumab if the cancer does not have a mutation in BRAF, as a second-line treatment following treatment with ipilimumab and if the cancer has a mutation in BRAF, with a BRAF inhibitor, as a second-line treatment for squamous non-small cell lung cancer, ...
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What Is Alemtuzumab? Alemtuzumab is an antibody made from animal DNA. Alemtuzumab is used to treat chronic B-cell lymphocytic leukemia or relapsing forms of multiple sclerosis. Lemtrada is available only from a certified pharmacy under a special program.
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What Is Dabrafenib? Be the first to review this Drug. Dabrafenib is a cancer medication that interferes with the growth and spread of cancer cells in the body. Dabrafenib is used to treat a certain type of metastatic melanoma (skin cancer that has spread to other parts of the body).
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What is Humalog (Insulin Lispro)? Humalog is the brand name for a fast-acting insulin called insulin lispro. Humalog Mix 75/25, and Humalog Mix 50/50, contain mixtures of insulin lispro along with a second form of insulin called lispro protamine. Humalog is a medication used to treat both type 1 diabetes and type 2 diabetes.
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Icatibant Icatibant is a synthetic peptidomimetic drug consisting of ten amino acids, and acts as an effective and specific antagonist of bradykinin B2 receptors. It has been approved in the EU for use in hereditary angioedema, and is under investigation for a number of other conditions in which bradykinin is thought to play a significant role.
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MetroGel What is metronidazole topical (MetroCream, MetroGel, MetroLotion, Noritate)? Metronidazole is an antibiotic that fights bacteria in the body. Metronidazole topical (for the skin) is used to treat skin lesions caused by rosacea.
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Ipilimumab (Yervoy Â®) Brand Name: Yervoy®. Ipilimumab is used in the treatment of melanoma, a type of skin cancer. Ipilimumab is a type of monoclonal antibody. This medicine is designed to boost the immune system. Normally, a protein called CTLA-4 helps to regulate the immune system by keeping its cells in check. Ipilimumab blocks the activity of CTLA-4, which frees the immune system to act against melanoma cells in the body.
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- DRUG CLASS AND MECHANISM: Diflunisal is a nonsteroidal anti-inflammatory drug (NSAID) that is effective in treating fever, pain, and inflammation in the body.Other members of this class include ibuprofen (Motrin), indomethacin (Indocin), nabumetone (Relafen), naproxen (Anaprox, Naprosyn, Aleve) and several others.r. Charles Pat Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ.
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Abilify Abilify® (aripiprazole) is a prescription medication that is used to treat schizophrenia and bipolar disorder. It is also approved to be used along with antidepressants for the treatment of major depression (this is known as augmentation). Recently, Abilify has also been approved for treating irritability associated with autism.
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Elmiron ELMIRON® is a prescription medication used to treat the bladder pain or discomfort associated with interstitial cystitis (IC). It is not known exactly how ELMIRON® works, but it is not a pain medication like aspirin or acetaminophen and therefore must be taken continuously for relief as prescribed by your doctor.
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Terbinafine Lamisil (terbinafine) is an antifungal medication that fights infections caused by fungus. Lamisil tablets are used to treat infections caused by fungus that affect the fingernails or toenails. Lamisil oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old.
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What Is Humira (Adalimumab)? A: Humira (adalimumab) is a medication that is used to treat various conditions including rheumatoid arthritis, Chrohn's disease, and psoriasis. It is in a class of medications called TNF inhibitors. TNF is a chemical in the body that is involved in inflammation and immune system responses.umira is a type of medication called a tumor necrosis factor (TNF) blocker, or anti-TNF drug. TNF blockers help reduce inflammation and slow the progression of inflammatory conditions by targeting TNF, a substance produced by the immune system that causes inflammation in the body.
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- Occasionally, the side effects of ipilimumab are life-threatening. It’s important to tell your doctor or nurse as soon as possible if you have moderate or severe side effects. During office hours, you can contact the clinic or ward where you had your treatment.
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Terbinafine What Is Terbinafine? Terbinafine hydrochloride (Lamisil®) is a prescription medication that is used to treat fingernail or toenail fungus. A new form (oral granules) has also been approved to treat a fungal infection called tinea capitis (also known as ringworm of the scalp).
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Birth Control Pills and Antibiotics Medications that Reduce Oral Contraceptive Effectiveness. Rifampin (other possible brand names include Rifampicin, Rifamycin, Rimactane, Rifadin, Rifamate) is a medication used to treat tuberculosis-a potentially serious infectious disease that usually affects the lungs but may also affect other parts of the body.
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meropenem (Merrem) Meropenem is an antibiotic. It fights bacteria in the body. Meropenem is used in the treatment of infections of the abdomen, such as appendicitis and peritonitis, bacterial meningitis (infection of the lining of the brain), and skin infections. Meropenem may also be used for purposes other than those listed here.
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- A drug called interferon is a type of immunotherapy. It is sometimes used to treat advanced squamous cell skin cancers. Basal cell skin cancers may be treated with imiquimod cream. This cream stimulates the immune system to attack the cancer.hotodynamic therapy (PDT). This is a relatively new type of treatment. It is another alternative to surgery. PDT uses a drug that makes skin cells sensitive to light. The area of skin that needs treating is exposed to a special type of light, and the cancer cells are destroyed.
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- Firdapse® is amifampridine phosphate or 3,4-diaminopyridine phosphate (3,4-DAP). It has received an orphan drug designation in the U.S. and orphan medicinal product designation in the European Union for the treatment of Lambert-Eaton Myasthenic Syndrome (LEMS).
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- Inositol hexaphosphate may be useful in reducing side effects from chemotherapy. Inositol hexaphosphate (IP6) is a molecule found naturally in cells, where it performs important messenger roles and affects numerous cellular processes. In laboratory experiments, it inhibited events involved in blood clotting.