amyloidosis definition
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- Amyloidosis is a rare and serious disease caused by accumulation of proteins in the form of abnormal, insoluble fibres, known as amyloid fibrils, within the extracellular space in the tissues of the body.
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Overview 1 Dialysis-related amyloidosis develops when proteins in blood are deposited in joints and tendons — causing pain, stiffness and fluid in the joints, as well as carpal tunnel syndrome. 2  This type generally affects people on long-term dialysis. 3  Symptoms. 4  Risk factors.
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MEDLINE Abstract 1985; 3(2):173-80 (ISSN: 0392-856X) Husby G. In spite of an apparent decrease in its occurrence during the last 2-3 decades, amyloidosis associated with rheumatoid arthritis is a significant cause of increased morbidity and early death in both juvenile- and adult-onset rheumatoid arthritis (RA).
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Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig's Disease) Medical Definition of Amyotrophic lateral sclerosis (ALS) Amyotrophic lateral sclerosis (ALS): A classic motor neuron disease. Motor neuron diseases are progressive chronic diseases of the nerves that come from the spinal cord responsible for supplying electrical stimulation to the muscles. This stimulation is necessary for the movement of body parts.
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- Amyloid protein can be deposited in a localized area and may not be harmful or only affect a single tissue of the body impairing its function. This form of amyloidosis is called localized amyloidosis. Amyloidosis that affects many tissues throughout the body is referred to as systemic amyloidosis.
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amyloidosis Definition of amyloidosis. : a disorder characterized by the deposition of amyloid in bodily organs and tissues.
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Amyloidosis Amyloidosis. Amyloidosis is a clinical disorder caused by extracellular and/or intracellular deposition of insoluble abnormal amyloid fibrils that alter the normal function of tissues.
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Keloid Keloid, also known as keloid disorder and keloidal scar, is the formation of a type of scar which, depending on its maturity, is composed mainly of either type III (early) or type I (late) collagen.
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Amyloidosis Amyloidosis is a condition in which an abnormal protein called amyloid builds up in your tissues and organs. When it does, it affects their shape and how they work. Amyloidosis is a serious health problem that can lead to life-threatening organ failure. Causes and Types of Amyloidosis
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- Amyloidosis is a disease that leads to the buildup of protein in vital organs, which causes these organs to become damaged. Treatment includes chemotherapy and steroids. Appointments 866.320.4573
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Amyloid Congo red stain. 1  The classical, histopathological definition of amyloid is an extracellular, proteinaceous deposit exhibiting beta sheet structure. 2  A more recent, biophysical definition is broader, including any polypeptide that polymerizes to form a cross-beta structure, in vivo or in vitro.
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- Cardiac (Heart) Amyloidosis. Amyloid deposits in the heart can make the walls of the heart muscle stiff. They can also make the heart muscle weaker and affect the electrical rhythm of the heart. This condition can cause less blood to flow to your heart. Eventually, your heart will no longer be able to pump.
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Stroke Caused by Amyloid Angiopathy Amyloid deposits may accumulate inside the walls of blood vessels in the brain. This is referred to as amyloid angiopathy. The accumulation of amyloid may cause blood vessels to deteriorate over time, until they eventually break down and bleed.
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Protein Structure amyloidosis. collection of D characterized by protein precipitation & aggregation of misfolded proteins; diff types lead to diff protein precipitates; precipitates often rich in beta sheets; can lead to organ failure; 2 types are AL amyloidosis & Alzheimer's D.
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- Read the Travelers' Diarrhea: What You Need to Know article > >. Amyloidosis : A group of diseases that results from the abnormal deposition of a protein called amyloid in tissues and organs. Bezoar: A clump of food or hair in the digestive tract. Bezoars can cause obstructions in the stomach that keep food from passing into the small intestine.
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- Definition of Problem. The keloid is defined as an abnormal scar that grows beyond the boundaries of the original site of skin injury. Keloids have the clinical appearance of a raised amorphous growth, as in the first 2 images below, and are frequently associated with pruritus and pain.
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acidosis Medical Definition of acidosis. plural. acidoses. \-ˌsēz\play. : an abnormal condition of reduced alkalinity of the blood and tissues that is marked by sickly sweet breath, headache, nausea and vomiting, and visual disturbances and is usually a result of excessive acid production—compare alkalosis, ketosis 1.
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WELCOME!Letâs Stay Connected. Sign-Up to receive breaking rare disease information, news and stories right to your inbox! (We value your privacy. Your email address will not be shared.)SIGN ME UP Secondary amyloidosis (AA) is caused by the inflammatory disease process that is part of the underlying disease. Approximately 50% of the people with secondary amyloidosis have rheumatoid arthritis as the underlying disease.
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Amyloidosis AA Amyloidosis AA usually begins as a disease in the kidneys, but other organs can be affected such as the liver and spleen. Medical or surgical treatment of the underlying infection or inflammatory disease can slow down or stop the progression of this condition.
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- Amyloidosis is rare, affecting about 8 persons per million annually. Its cause is not known, but there is a definate link between indoor fungal exposure and this afflication. It can affect anyone, but the majority of people who get amyloidosis are over the age of 40. Primary amyloidosis is not contagious or inherited. It is not known how many people have this disease. About 10 percent of patients who have multiple myeloma (a form of bone marrow cancer), develop amyloidosis.
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AMYLOIDOSIS AMYLOIDOSIS Dictionary entry overview: What does amyloidosis mean? • AMYLOIDOSIS (noun) The noun AMYLOIDOSIS has 1 sense: 1. a disorder characterized by deposit of amyloid in organs or tissues; often secondary to chronic rheumatoid arthritis or tuberculosis or multiple myeloma Familiarity information: AMYLOIDOSIS used as a noun is very rare.
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- Primary amyloidosis can occur with a bone marrow cancer of plasma cells called multiple myeloma (fewer than 20% of AL patients). Primary amyloid is not associated with any other diseases but is a disease entity of its own, conventionally requiring chemotherapy treatment.
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- amyotrophic lateral sclerosis. (ā'mī-ə-trō'fĭk, -ə-trŏf'ĭk, ā-mī'-) A chronic, progressive neurologic disease marked by gradual degeneration of the neurons in the spinal cord that control voluntary muscle movement. The disorder causes muscle weakness and atrophy and usually results in death.
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- Familial amyloidosis (ATTR, AApoAI, AApoAII, AGel, ALys, AFib) is a rare form of inherited amyloidosis. It is more common in African-Americans. The amyloid deposits in most familial amyloidosis are composed of the protein transthyretin, or TTR, which is made in the liver.