causes of hepatomegaly and splenomegaly
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Causes of Hepatomegaly Causes of hepatomegaly are classified as conditions and/or diseases that disrupt liver functions to create abnormal swelling. Glycogen storage disease, leukemia and liver cancer are also causes of an enlarged liver. Risk factors of hepatomegaly are smoking, excessive alcohol consumption, STDs such as Hepatitis B, drug use and abuse, diabetes and obesity. The following risk factors can cause hepatomegaly to occur: Alcoholism.
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Hepatomegaly To avoid missing a really big liver, always begin liver palpation in the LIF and work towards the right upper quadrant. The most common causes of hepatomegaly in the UK are alcoholic liver disease, malignancy (particularly metastases) and congestive cardiac failure.
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- A Doctor's View on Enlarged Spleen (Splenomegaly) Causes. The spleen helps your body fight bacteria and infections. Diseases and conditions cause the spleen to become enlarged. Some of the common causes that may enlarge your spleen are liver disease, cancers, infections, inflammation of the heart. Read the entire Doctor's View.
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- The spleen is part of the lymphatic system, which plays a role in immunity and maintenance of healthy blood cells. It is an important organ and is affected by disorders of the blood, liver, and immune system. An enlarged spleen is known as splenomegaly. Although hepatosplenomegaly often produces no symptoms, it is known to cause abdominal pain in the upper portion of your abdomen.
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- What is Hepatopulmonary Syndrome. Hepatopulmonary Syndrome (HPS) is a rare abnormality of the lung which is caused by liver disease. Although not all patients with liver disease get this lung abnormality, patients who do have it can become short of breath and have low oxygen levels.
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Hepatomegaly Hepatomegaly in neonates and children. 1  Infections: TORCH* infections, hepatitis viruses and EBV and malaria. 2  Metabolic: galactosaemia, lipid storage disorders - eg, Gaucher's disease. 3  Neoplastic: leukaemia, lymphoma and hepatoblastoma. 4  Haematological: sickle cell anaemia and thalassaemia.
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Growth Hormone High growth hormone (GH) levels associated with high insulinlike growth factor 1 (IGF-1) levels and normal GH and IGF-1 receptors cause gigantism in children or acromegaly in adults, and it is seen in the following conditions: Pituitary gland tumor (mostly, benign adenoma) Multiple endocrine neoplasia type I (MEN-I)
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- Acromegaly is a rare disease typically caused by a noncancerous tumor in the pituitary gland. Acromegaly is caused by the excess secretion of growth hormone (GH). It can cause noticeable changes in your appearance, such as enlarged hands, feet, and facial features, and increased spaces between teeth.It also can affect your metabolism.cromegaly is caused by the excess secretion of growth hormone (GH). It can cause noticeable changes in your appearance, such as enlarged hands, feet, and facial features, and increased spaces between teeth.
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splenomegaly splenomegaly. enlargement of the spleen. congestive splenomegaly splenomegaly secondary to portal hypertension, with ascites, anemia, thrombocytopenia, leukopenia, and episodic hemorrhage from the intestinal tract.Called also Banti's disease.hemolytic splenomegaly enlargement of the spleen associated with hemolytic diseases of the blood.plenomegaly. congestive splenomegaly Banti's disease; splenomegaly secondary to portal hypertension. hemolytic splenomegaly that associated with any disorder causing increased erythrocyte degradation.
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Acromegaly Acromegaly is a serious condition that occurs when the body produces too much of the hormones that control growth. This causes abnormal enlargement of bone, cartilage, muscle, organs, and other tissues. This abnormal growth can cause serious disease and even premature death.
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Acromegaly Causes The root cause of acromegaly is excessive secretion of growth hormone (GH), caused by either a pituitary tumor or a non-pituitary tumor. Too much GH leads to a cascade of events and the symptoms of acromegaly.
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What Causes Enlarged Spleen? Splenomegaly is a condition that occurs when your spleen becomes enlarged. It is also commonly referred to as enlarged spleen or spleen enlargement. The spleen is a part of your lymphatic system. The spleen helps the immune system by storing white blood cells and helping in the creation of antibodies.
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splenomegaly Enlarged spleen Enlargement of spleen for any reason, which is usually a manifestation of underlying disease; the only specific finding in splenomegaly is dragging sensation in the upper right quadrant; megalic spleens may reach 4.0+ kg–eg, in agnogenic myeloid metaplasia.plenomegaly. congestive splenomegaly Banti's disease; splenomegaly secondary to portal hypertension. hemolytic splenomegaly that associated with any disorder causing increased erythrocyte degradation.
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Hepatomegaly Hepatomegaly is the condition of having an enlarged liver. It is a non-specific medical sign having many causes, which can broadly be broken down into infection, hepatic tumours, or metabolic disorder. Often, hepatomegaly will present as an abdominal mass. Depending on the cause, it may sometimes present along with jaundice.
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Enlarged liver URL of this page: //medlineplus.gov/ency/article/003275.htm. Hepatomegaly is swelling of the liver beyond its normal size. If both the liver and spleen are enlarged, it is called hepatosplenomegaly. The lower edge of the liver normally comes just to the lower edge of the ribs on the right side. The edge of the liver is normally thin and firm. It cannot be felt with the fingertips below the edge of the ribs, except when you take a deep breath. It may be enlarged if a health care provider can feel it in this area.
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- The size and weight of your liver increases with your age and body weight. Sex and body shape also influence the size of your liver. Hepatomegaly is the enlargement of your liver. An enlarged liver is a sign that something is seriously wrong with your health. Hepatomegaly is always a cause for medical evaluation, although not all of the underlying conditions that cause it are medical emergencies.
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Enlarged Spleen (Splenomegaly) Enlarged Spleen Causes. The causes of splenomegaly vary widely and range from malignancy (cancers), infections, congestion (increased blood flow), infiltration of the spleen from other diseases, inflammatory conditions, and blood cell diseases. Some of the most common causes of an enlarged spleen include the following: liver disease (cirrhosis due to chronic hepatitis B, chronic hepatitis C, fatty liver, long standing alcohol abuse); blood cancers (lymphoma, leukemia, myelofibrosis);
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A to Z List of Neurological Disorders An enlarged liver and spleen, medically known as hepatosplenomegaly, occur when the liver and spleen swell beyond their normal size.t is an important organ and is affected by disorders of the blood, liver, and immune system. An enlarged spleen is known as splenomegaly. Although hepatosplenomegaly often produces no symptoms, it is known to cause abdominal pain in the upper portion of your abdomen.
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- Many of the symptoms that cause hepatomegaly can impair your liver’s ability function and help your body. While hepatomegaly is always a cause for medical evaluation, not all of the underlying conditions are considered medical emergencies.
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What is Organomegaly? Organomegaly involves the enlargement of body organs. Many different factors may cause such enlargement. While some causes are benign, others are more serious. Heart enlargement, liver enlargement, and spleen enlargement — called cardiomegaly, hepatomegaly, and splenomegaly, respectively — represent three examples of abnormal organ enlargement.
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The Lymphatic and Immune Systems Splenomegaly: Abnormal enlargement of the spleen. Splenomegaly is a sign of an underlying condition, such as severe liver disease, leukemia, or mononucleosis. Patients with splenomegaly should avoid activities that risk trauma to the abdomen, including contact sports, because of risk of bleeding from the injured spleen.
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Enlarged Spleen (Splenomegaly) An enlarged spleen is not normal and occurs as a consequence of another underlying disease. An enlarged spleen is caused by infections (mononucleosis, toxoplasmosis, endocarditis); liver diseases (cirrhosis); cancer; inflammatory diseases (rheumatoid arthritis, sarcoidosis); trauma; and.
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Acromegaly What causes acromegaly? Overproduction of growth hormone (GH) by the pituitary gland over a long period of time causes acromegaly. There are several reasons for overproduction of GH. The most common reason is the presence of a pituitary adenoma, which is a benign (non-cancerous) tumor of the pituitary gland. These tumors produce excess GH.
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Growth hormone The effects of growth hormone (GH) deficiency vary depending on the age at which they occur. Alterations in somatomedin can result in growth hormone deficiency with two known mechanisms; failure of tissues to respond to somatomedin, or failure of the liver to produce somatomedin.
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Hepatomegaly Hepatomegaly is the condition of having an enlarged liver. It is a non-specific medical sign having many causes, which can broadly be broken down into infection, hepatic tumours, or metabolic disorder. Often, hepatomegaly will present as an abdominal mass.