what causes a peptic ulcer
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Overview The most common symptom of a peptic ulcer is stomach pain. The most common causes of peptic ulcers are infection with the bacterium Helicobacter pylori (H. pylori) and long-term use of aspirin and certain other painkillers, such as ibuprofen (Advil, Motrin, others) and naproxen sodium (Aleve, Anaprox, others). Stress and spicy foods do not cause peptic ulcers.
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Chest Pain Peptic inflammation is inflammation caused by stomach acid. Inflammation may be in the stomach; in the first part of the small intestine (the duodenum), as acid flows in with food; or in the lower gullet (oesophagus), if acid splashes up to cause reflux oesophagitis. A peptic ulcer is an ulcer caused by stomach acid. An ulcer occurs where the lining of the gut is damaged and the underlying tissue is exposed. If you could see inside your gut, an ulcer looks like a small, red crater on the inside lining of the gut. The duodenum is the most common site for a peptic ulcer.
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Gastric Ulcer Back to TopCauses. Non-cancerous (benign) gastric ulcers are caused by an imbalance between stomach acid, an enzyme called pepsin, and the natural defenses of the stomach''s lining. This imbalance leads to inflammation, which can be made worse by aspirin and nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen.
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Surprising Risk Factors for Stomach Ulcers Prolonged use of non-steroidal anti-inflammatory drugs (NSAIDs) — common over-the-counter medications such as aspirin and ibuprofen — can cause ulcers by inhibiting a special enzyme in the stomach called COX-1.
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- ​A peptic ulcer is a sore on the lining of your stomach or duodenum. People who take NSAIDs such as aspirin and ibuprofen long-term or are infected with the bacteria H. pylori are most likely to develop peptic ulcers.​. Symptoms and Causes of Peptic Ulcer Disease.
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Peptic Ulcers (Stomach Ulcers) A peptic ulcer (stomach ulcer) is a sore on the lining of your stomach or duodenum. People who take NSAIDs such as aspirin and ibuprofen long-term or are infected with the bacteria H. pylori are most likely to develop peptic ulcers.
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- 1 Peptic ulcers are sores in the lining of the stomach or duodenum. 2  Peptic ulcer formation is related to H. pylori bacteria in the stomach and nonsteroidal anti-inflammatory medications (NSAIDs) in 50% of patients.
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- Helicobacter pylori (H pylori) is the name of a bacteria that can cause peptic ulcers. It can infect the stomach lining, dissolving the mucus film that protects it from the highly acidic stomach contents. This causes a burning pain in the stomach.
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Summit Medical Group Web Site It’s also called a gastric ulcer or peptic ulcer. The lining of the stomach normally keeps the stomach from being hurt by stomach acid and digestive juices. If this protective layer breaks down, stomach acids can damage the walls of your stomach and cause an ulcer. You may get an ulcer when: You have bacteria called Helicobacter pylori (H. pylori). These bacteria are the most common cause of ulcers. When H. pylori bacteria infect the stomach, the infection can weaken the lining of the stomach.
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Gastritis and Peptic Ulcer Disease Caused by Helicobacter pylori There is a plethora of literature concerning gastritis and peptic ulcer disease caused by the bacterium Helicobacter pylori. Nevertheless, there is still much to be learned about this bacterium and its effects on the human body.
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Helicobacter Pylori Infections Helicobacter pylori (H. pylori) is a type of bacteria that causes infection in the stomach. It is the main cause of peptic ulcers, and it can also cause gastritis and stomach cancer. About 30 to 40 percent of people in the United States get an H. pylori infection. Most people get it as a child. H. pylori usually does not cause symptoms. But it can break down the inner protective coating in some people's stomachs and cause inflammation. This can lead to gastritis or a peptic ulcer. Researchers aren't sure how H. pylori spreads.
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Peptic Ulcer Peptic ulcers happen when the acids that help you digest food damage the walls of the stomach or duodenum. The most common cause is infection with a bacterium called Helicobacter pylori. Another cause is the long-term use of nonsteroidal anti-inflammatory medicines (NSAIDs) such as aspirin and ibuprofen. Stress and spicy foods do not cause ulcers, but can make them worse.
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- A Peptic Ulcer is an open sore in the lining of the stomach or duodenum (upper intestine). The most common cause of peptic ulcer disease is a bacterial infection (H pylori) in the stomach. Another common cause is taking anti-inflammatory medications (such as ibuprofen, prednisone, and aspirin).Gastritis is an irritation of the stomach lining. It can be acute (recent) or chronic (lasting a long time).he symptoms of gastritis and peptic ulcer are very similar. Both can cause a dull ache or burning pain in the upper abdomen. Other symptoms include nausea, vomiting, loss of appetite, and belching or bloating.
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- How Ulcers Form. When H. pylori bacteria do cause ulcers, here's how doctors think it happens: Bacteria weaken the protective coating of the stomach and upper small intestine. Acid in the stomach then gets through to the sensitive tissues lining the digestive system underneath. Acid and bacteria directly irritate this lining resulting in sores, or ulcers.
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Understanding Ulcers Until the mid-1980s, the conventional wisdom was that ulcers form as a result of stress, a genetic predisposition to excessive stomach acid secretion, and poor lifestyle habits (including overindulging in rich and fatty foods, alcohol, caffeine, and tobacco).veruse of over-the-counter painkillers (such as aspirin, ibuprofen, and naproxen), heavy alcohol use, psychological stress, and smoking exacerbate and may promote the development of ulcers, especially in someone with H. pylori. Other studies show that stomach ulcers are more likely to develop in older people.
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What Causes Ulcers? Stomach and duodenal ulcers are usually due to one of two causes: the bacterium Helicobacter pylori or nonsteroidal anti — inflammatory drugs (NSAIDs) like aspirin, ibuprofen, and naproxen. An ulcer, regardless of the cause, can cause abdominal pain, bleeding, or even cause a hole (perforation).An ulcer is maintained by an acid environment in the stomach and pepsin, which is produced in the stomach. Chronic infection with H. pylori causes an increase in acid.irst off, let's not buy into the myth that ulcers are caused by a bacteria called H. pylori. Just not true. Ulcers are caused by the prior use of a medication that destroyed your mucosal lining, thus leaving your stomach tissue exposed to your own digestive acids, which then eat a hole right through the flesh.
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What is the main cause of an ulcer? Acid and Pepsin. Too much acid and pepsin can damage a healthy stomach lining and cause ulcers. Most times the damage is caused by other factors first, weakening the stomach linings protective mucus layer defenses to a point when even an ordinary level of gastric acid can cause an ulcer.
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- The two most common causes of peptic ulcers are: 1  Infection withHelicobacter pylori(H. pylori) bacteria. 2  Nonsteroidal anti-inflammatory drugs (NSAIDs).
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What Is a Peptic Ulcer? In fact, the most common causes of ulcers are: 1  Helicobacter pylori, a type of bacteria that can infect your stomach.  Non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin, Advil or Motrin (ibuprofen), Aleve (naproxen), and others.
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- Most duodenal ulcers are caused by the H pylori bacteria. This bacteria burrows into the lining of the stomach and duodenum, thereby compromising the protective layer. Acid and digestive enzymes then cause the ulcer. Gastric Ulcer. A gastric ulcer is located in the stomach proper and is second most common of the types of stomach ulcers. This ulcer type is also caused by H pylori the majority of the time. Gastric ulcers do have a few differences.
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Peptic Ulcer Peptic ulcers are sores that develop in the lining of the stomach, esophagus, or rarely in small intestine. They are usually caused by H. pylori, excessive NSAID or alcohol usage, smoking, or stomach cancer.
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Top 30 Doctor insights on: Duodenal Wall Thickening The most common cause of duodenal ulcer is a stomach infection associated with the Helicobacter pylori (H pylori) bacteria. Other risk factors for duodenal ulcers include overuse of alcohol, tobacco, and medications such as aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs). duodenal ulcer is a type of peptic ulcer that occurs in the duodenum, the beginning of the small intestine. Peptic ulcers are eroded areas in the lining of stomach and duodenum, which result in abdominal pain, possible bleeding, and other gastrointestinal symptoms.
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Peptic Ulcer Disease Ulcers that do not heal with treatment may indicate a resistant form of H. pylori or the presence of other factors interfering with the healing process like smoking, alcohol or NSAID use. Rare causes of ulcers include extreme overproduction of stomach acid (Zollinger-Ellison syndrome), stomach cancer, or Crohn’s disease.
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- Helicobacter pylori is the cause of most peptic ulcer disease and a primary risk factor for gastric cancer. Eradication of the organism results in ulcer healing and reduces the risk of ulcer recurrence and complications.
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ulcer An estimated 90% of peptic ulcers are caused by infection with a bacterium, Helicobacter pylori, strains of which promote the formation of ulcers by causing an inflammtory response in the cells of the stomach wall, making it more susceptible to the hydrochloric acid secreted by the stomach.