what is homocysteine level normal range
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- The normal range of homocysteine levels for people up to age 30 is 4.6 to 8.1 micromoles per liter (mcmol/L). Between ages 30 and 59, normal ranges are 6.3 to 11.2 mcmol/L for men and 4.5 to 7.9 mcmol/L for women.
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iron What is the normal iron level in the human body? Normal serum iron level ranges from 60 - 170 μg/dL for men and 30 - 126 μg/dL for women. Lower levels may indicate iron deficiency, chronic gastrointestinal blood loss or menstrual bleeding, or pregnancy. Higher levels may suggest iron overloading, broken blood cells, hepatitis, or vitamin B12 or B6 deficiency.
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- A homocysteine blood test is done to: 1  Help identify vitamin B12 deficiency or folic acid deficiency. But other tests for these deficiencies are available.  Help identify a rare inherited disease (homocystinuria) that causes a deficiency of one of several enzymes needed to convert food to energy.
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homocysteine The level of homocysteine in the blood is influenced by the presence of these substances. Homocystinuria is a rare genetic disorder that occurs in about one in every 200,000 individuals. This congenital metabolic disorder causes large amounts of homocysteine to be excreted in the urine.
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What Are the Health Risks for Elevated Homocysteine Levels? Cysteine also acts as an anti-oxidant. If homocysteine cannot be converted into cysteine or returned to the methionine form, levels of homocysteine in the body increase. Elevated homocysteine levels have been associated with heart attack, stroke, blood clot formation, and perhaps the development of Alzheimer's disease.
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Andrew's Nutritional Health Resources Most labs report a normal homocysteine should be in the range of 5 to 12 or even 15 micromols/L. If your homocysteine level is above 12 micromols/L, you are in serious trouble.
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- A homocysteine blood test is done to: 1  Help identify vitamin B12 deficiency or folic acid deficiency. But other tests for these deficiencies are available. 2  Help identify a rare inherited disease (homocystinuria) that causes a deficiency of one of several enzymes needed to convert food to energy.
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Is Homocysteine Making You Sick? A New Bioactive Form of Folic Acid Can Lower Stubbornly High Homocysteine Levels When Ordinary B-Vitamins Fail. Many people suffering from cardiovascular disease, stroke, migraines, and dementia could be suffering from the adverse effects of elevated levels of homocysteine in their blood.
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- He also had high homocysteine level, due to his MTHFR gene mutation (he is homozygous C677t) and this is now corrected on methyl B12 and FolaPro (5-methyltetrahydrofolate) . ...He takes a high potency B....
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- Supplementation to normalise homocysteine levels. Your homocysteine level is a very good indicator of the amount of certain B vitamins, and other nutrients, you need. Homocysteine can be measured by either your GP or through a home test kit. The chart below shows you the approximate level that is worth supplementing on a daily basis.
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homocysteine Homocysteine is a sulfur-containing amino acid that occurs naturally in all humans. It is broken down in the body through two metabolic pathways. The chemical changes that must occur to break down homocysteine require the presence of folic acid (also called folate) and vitamins B6 and B12.
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Elevated Homocysteine There is no treatment for elevated homocysteine apart from efforts to lower your levels by increasing your intake of B vitamins through the eating of more green leafy vegetables, fruits and more grain-based foods fortified with folic acid.
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MTHFR Mutation Two copies of A1298C are not typically associated with increased homocysteine levels. If the MTHFR mutation test is negative, then the C677T and A1298C mutations were not detected and the tested person's elevated homocysteine level is likely due to another cause.he MTHFR mutation test may sometimes be ordered when a person has elevated homocysteine levels, especially when the person has a personal or family history of premature cardiovascular disease or thrombosis.
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- Figure 3. Sensitivity analysis of the pooled odds ratio coefficients for the differences of serum homocysteine (Hcy) level between diabetic peripheral neuropathy patients and the healthy controls. Figure 4. Funnel plot of publication biases for the differences of serum homocysteine (Hcy) level between diabetic. peripheral neuropathy patients and the healthy controls. a nonprotein amino acid containing sulfur and can function as an intermediate in the metabo-. lism of methionine (Huang et al., 2013).
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How to Increase Homocysteine Levels The caffeine found in coffee has been found to raise levels of homocysteine. 1  Decreasing your intake of B vitamins and folic acid in your diet can also cause deficiencies that are linked to other problems, such as neuropathy, or numbness and pain in the extremities, and anemia.tep 1. Determine your homocysteine level. Before you make any adjustments to your homocysteine levels, you need to know your current blood level. Talk with your health care professional to obtain a blood test that will tell you where you need to start.
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Vitamin B12 and Folate B12 and folate levels may be ordered when a complete blood count (CBC) and/or blood smear, done as part of a health checkup or an evaluation for anemia, indicates a low red blood cell (RBC) count with the presence of large RBCs. Specifically, a high mean corpuscular volume (MCV) indicates that the RBCs are enlarged.ther laboratory tests that may be used to help detect B12 and folate deficiencies include homocysteine and methylmelonic acid (MMA) . Homocysteine and MMA are elevated in B12 deficiency while only homocysteine, and not MMA, is elevated in folate deficiency.
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Hyperhomocysteinemia As a consequence of the biochemical reactions in which homocysteine is involved, deficiencies of vitamin B6, folic acid (vitamin B 9), and vitamin B12 can lead to high homocysteine levels. Hyperhomocysteinemia is typically managed with vitamin B6, vitamin B9 and vitamin B12 supplementation.
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Vitamin C Many studies have investigated the health effects of high homocysteine levels and/or having two C677T MTHFR gene mutations. Some studies suggest that an elevated level of homocysteine in the blood is associated with an increased risk for heart disease, including coronary heart disease and stroke.
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- Homocysteine is an amino acid that occurs naturally in your body. In recent years‚ studies have lead researchers to believe that excessively high levels of homocysteine are a sign of—and a possible contributing factor to—many serious medical conditions.
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MTHFR Mutation If a person has two copies (homozygous) of MTHFR C677T, or has one copy of C677T and one of A1298C, then it is likely that elevated homocysteine levels are due to these inherited mutations, or that the mutations are contributing to them.f a person has two copies (homozygous) of MTHFR C677T, or has one copy of C677T and one of A1298C, then it is likely that elevated homocysteine levels are due to these inherited mutations, or that the mutations are contributing to them.
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Hyperhomocysteinemia There is also evidence that elevated homocysteine levels and low levels of vitamin B6 and B12 are risk factors for mild cognitive impairment and dementia. Oxidative stress induced by homocysteine may also play a role in schizophrenia.
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- In cases of suspected malnutrition or vitamin B12 or folate deficiency, homocysteine levels may be elevated. If an individual does not get enough B vitamins and/or folate through diet or supplements, then the body may not be able to convert homocysteine to forms that can be used by the body.
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Andrew's Nutritional Health Resources The higher these levels the greater your risk of having a heart attack or stroke. Most labs report a normal homocysteine should be in the range of 5 to 12 or even 15 micromols/L. If your homocysteine level is above 12 micromols/L, you are in serious trouble.
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Ammonia levels range in blood Read More. The normal ammonia range is 10–47 μmol/L. High ammonia levels and signs of hepatic encephalopathy is a worsening of brain function that occurs when the liver is no longer able to remove toxic substances in the blood due to cirrhosis. Symptoms may be mild at first.
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Homocysteine â What Can High Levels Do To You? High levels of stress can also increase your homocysteine levels and lead to further oxidative damage. A small percentage of patients have a genetic predisposition for elevated homocysteine levels due to a MTHFR mutation. It is still possible to lower the homocysteine levels, however.
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- In a clinical study with more than 1,500 patients, Dr. K. Robinson from the Cleveland Clinic Foundation in Ohio showed that blood levels of vitamin B6, vitamin B12 and folic acid are important in lowering homocysteine levels and decreasing the risk of coronary heart disease.