myc gene definition
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What does MYCstand for? Myc. Myc is a regulator gene that codes for a transcription factor. A mutated version of Myc is found in many cancers, which causes Myc to be constitutively expressed. This leads to the unregulated expression of many genes, some of which are involved in cell proliferation, and results in the formation of cancer. A common human translocation involving Myc is t which is critical to the development of most cases of Burkitt's Lymphoma. Malfunctions in Myc have also been found in carcinoma of the cervix, colon, breast, lung and stomach.
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FPC A gene on chromosome 5q21-q22 that encodes a tumour-suppressor protein which acts as an antagonist of the Wnt signalling pathway. APC is also involved in cell migration and adhesion, transcriptional activation, and apoptosis. Molecular Pathology. APC mutations cause familial adenomatous polyposis.
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- Chronic myelogenous leukemia. [edit on Wikidata] Chronic myelogenous (or myeloid or myelocytic) leukemia (CML), also known as chronic granulocytic leukemia (CGL), is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood.
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gene gene. the structural unit of inheritance in living organisms. A gene is, in essence, a segment of DNA that has a particular purpose, i.e., that codes for (contains the chemical information necessary for the creation of) a specific enzyme or other protein.
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Chronic myelogenous leukemia Chronic myelogenous leukemia (CML) is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood.
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- The Genetic Code. The Central Dogma (Crick's term) of molecular biology (that is, biological chemistry). 1  DNA is the repository of all of the information necessary for the construction of an organism; that is, DNA is the genetic material. 2  A gene is a segment of DNA that codes for a specific protein or functional RNA.
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genetic code genetic code. the arrangement of nucleotides in the polynucleotide chain of a chromosome that governs the transmission of genetic information to proteins, i.e. determines the sequence of amino acids in the polypeptide chain making up each protein synthesized by the cell. See also genetic code.
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- Use * to search with a root symbol (eg ZNF*) HGNC is responsible for approving unique symbols and names for human loci, including protein coding genes, ncRNA genes and pseudogenes, to allow unambiguous scientific communication.
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- Medical Definition of genetic code. : the biochemical basis of heredity consisting of codons in DNA and RNA that determine the specific amino acid sequence in proteins and that appear to be uniform for all known forms of life.
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- Research the causes of related medical symptoms such as: 1  Swelling (3730 causes). 2  Swelling symptoms (3730 causes). 3  One. 4  Leg. 5  Leg symptoms (2751 causes). 6  Leg disease. 7  Leg disorder.
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TFRC Gene  (Protein Coding) GeneCards Summary for TFRC Gene. TFRC (Transferrin Receptor) is a Protein Coding gene. Diseases associated with TFRC include Immunodeficiency 46 and Gastric Adenosquamous Carcinoma. Among its related pathways are Vesicle-mediated transport and Iron metabolism in placenta.
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Major histocompatibility complex Major histocompatibility complex (MHC) Major histocompatibility complex (MHC), group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances. MHC proteins are found in all higher vertebrates. In human beings the complex is also called the human leukocyte antigen (HLA) system.
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gene gene. n. A hereditary unit consisting of a sequence of DNA that occupies a specific location on a chromosome and is transcribed into an RNA molecule that may function directly or be translated into an amino acid chain. Genes undergo mutation when their DNA sequences change. [German.
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Gene DCC gene (d eleted in c olorectal c arcinoma) a gene normally expressed in the mucosa of the colon but reduced or absent in a small proportion of patients with colorectal cancer. dominant gene one that produces an effect (the phenotype) in the organism regardless of the state of the corresponding allele. An example of a trait determined by a dominant gene is brown eye color. See also heredity. histocompatibility gene one that determines the specificity of tissue antigenicity (hla antigens) and thus the compatibility of donor and recipient in tissue transplantation and blood transfusion.
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Histone code From Wikipedia, the free encyclopedia. The histone code is a hypothesis that the transcription of genetic information encoded in DNA is in part regulated by chemical modifications to histone proteins, primarily on their unstructured ends.
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Hemoglobin C Disease Hemoglobin C (Hb C) is one of the most common structural hemoglobin variants in the human population. Persons with hemoglobin C trait (Hb AC) are phenotypically normal, with no clinically evident limitations or symptoms, while those with hemoglobin C disease (Hb CC) may have a mild degree of hemolytic anemia, splenomegaly, and borderline anemia.
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The major histocompatibility complex and its functions Summary. The major histocompatibility complex (MHC) of genes consists of a linked set of genetic loci encoding many of the proteins involved in antigen presentation to T cells, most notably the MHC class I and class II glycoproteins (the MHC molecules) that present peptides to the T-cell receptor.he major histocompatibility complex is located on chromosome 6 in humans and chromosome 17 in the mouse and extends over some 4 centimorgans of DNA, about 4 × 10 6 base pairs. In humans it contains more than 200 genes.
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Chronic myelogenous leukemia Chronic myelogenous leukemia is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood. CML is a clonal bone marrow stem cell disorder in which a proliferation of mature granulocytes and their precursors is found. It is a type of myeloproliferative neoplasm associated with a characteristic chromosomal translocation called the Philadelphia c
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myc Oncogenic expression of c-myc involves mutations on exon 2, which occur in more than 50% of Burkitt's lymphomas. The typical translocation in Burkitt’s lymphoma is t(8;14)(q24;q23), juxtaposing the c-myc and the immunoglobulin heavy-chain genes.
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Vitamin D-binding protein Vitamin D-binding protein. Vitamin D-binding protein, also/originally known as gc-globulin (group-specific component), is a protein that in humans is encoded by the GC gene. Contents.
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- MYC! is a Creative Youth Marketing cum Advertising Agency that provides a Creative Platform for global brands to engage with the Youth Market. Malaysian Youth Community has a history (since 2000) of developing Young People in Malaysia by involving them interactively with the Creative Branding Programs that we conduct.
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- Circumstances have forced him to move from...Starring: Henry Kelemen, Julianne Nicholson, Ethan Hawke Dark Places 6.3 26% Libby Day, resident of a Kansas farming community, is the sole survivor of a mas...Starring: Charlize Theron, Sterling Jerins, Nicholas Hoult.
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Chronic Leukemias Definition. The chronic leukemias are a group of malignancies involving the hematopoietic system. Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm that arises from a clonal process involving an early progenitor hematopoietic stem cell.
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Genetic Marker: Its Definition, Introduction, Background and Types A genetic marker is defined as a specific gene or DNA sequence that produces a detectable trait with a known location on a chromosome and that can be used to study family and population, identification of cells, species or individual. Introduction:
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gene (jēn) A segment of DNA, occupying a specific place on a chromosome, that is the basic unit of heredity. Genes act by directing the production of RNA, which determines the synthesis of proteins that make up living matter and are the catalysts of all cellular processes.
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APC gene The APC gene provides instructions for making the APC protein, which plays a critical role in several cellular processes. The APC protein acts as a tumor suppressor, which means that it keeps cells from growing and dividing too fast or in an uncontrolled way. It helps control how often a cell divides, how it attaches to other cells within a tissue, and whether a cell moves within or away from a tissue.