what gene causes atherosclerosis
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Rare and Common Genetic Differences Contributing to Susceptibility to Atherosclerosis Most of our success in understanding the genetic basis of common forms of atherosclerosis has come from studies of “candidate genes,” genes identified by biochemists and subsequently examined for genetic differences and associations in populations. A good example of a candidate gene is apolipoprotein E (apoE).
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What Causes Achondroplasia? In most cases, this common type of short-limbed dwarfism is related to a genetic mutation in the fibroblast growth factor receptor 3 gene. There are two possible causes of achondroplasia. One possible cause is a genetic mutation in the fibroblast growth factor receptor 3 (FGFR3) gene located on chromosome 4.The other possible cause is that the condition can be inherited from a parent with achondroplasia.here are two possible causes of achondroplasia. One possible cause is a genetic mutation in the fibroblast growth factor receptor 3 (FGFR3) gene located on chromosome 4.
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Atherosclerosis Atherosclerosis is a disease in which plaque builds up inside your arteries. Arteries are blood vessels that carry oxygen-rich blood to your heart and other parts of your body. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood.Over time, plaque hardens and narrows your arteries.oronary Heart Disease. Coronary heart disease (CHD), also called coronary artery disease, occurs when plaque builds up in the coronary arteries. These arteries supply oxygen-rich blood to your heart.
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- This includes underlying blood vessel conditions, such as atherosclerosis or an aneurysm. In atherosclerosis, blood vessel symptoms result when plaque builds up in the arteries that carry blood to the head, organs and limbs. Most commonly, people develop atherosclerosis as a result of diabetes, genetic risk factors, high blood pressure, a high-fat diet, obesity, high blood cholesterol levels, and smoking.
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Egg Consumption & LDL Cholesterol Size Nonmodifiable. 1  Advanced age. 2  Male sex. 3  Having close relatives who have had some complication of atherosclerosis (e.g. coronary heart disease or stroke) 4  Genetic abnormalities, e.g. familial hypercholesterolemia.
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What is atherosclerosis? Atherosclerosis is a disease process in which plaque (a mixture of cholesterol, calcium, and blood-clotting materials) builds up on the inner walls of the arteries. Atherosclerosis narrows arteries and causes them to harden, thicken, and become less elastic.therosclerosis is a medical condition in which a fatty substance called plaque builds up on the inside walls of blood vessels, which can slow or eventually block the flow of blood. When this occurs in the coronary arteries, it is termed coronary artery disease, or CAD.
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Abdominal Aortic Aneurysm Risk factors for atherosclerosis include: 1  Age (older than age 60) 2  Male (occurrence in males is 4 to 5 times greater than that of females) 3  Family history (first degree relatives such as father or brother) 4  Genetic factors. 5  High cholesterol. 6  High blood pressure. 7  Smoking. 8  Diabetes. 9  Obesity.
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New genetic cause of osteoporosis found, rare gene identified Genes are not solely to blame for the cause of osteoporosis; there are other factors as well which can lead to osteoporosis. Osteoporosis is the loss of bone mass. For example, being deficient or not consuming enough calcium can contribute to loss of bone mass, which then contributes to osteoporosis.ew genetic cause of osteoporosis found, rare gene identified. By: Bel Marra Health | Osteoporosis | Tuesday, September 15, 2015 - 17:30 PM. A rare gene – the EN1 gene – has been identified as a potential osteoporosis cause by researchers at McGill University.
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Large Gene Study Links Plaque In Heart Disease To Inflammation email. MNT featured Academic journal. By linking 15 new genetic regions to coronary artery disease, a large international study sheds new light on the underlying causes of this most common form of heart disease, which results from the build up of fatty material or plaque on the insides of the blood vessels of the heart.he 15 new genetic regions brings to 46 the total number of genetic links with heart disease found through genome-wide association studies (GWAS). The researchers found that 25% of the genetic regions were also strongly linked with cholesterol, especially with high levels of of LDL, the so-called bad cholesterol.
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atherosclerosis Arteriosclerosis is a broad term that includes a hardening of the inner and middle layers of the artery. It can be caused by normal aging, by high blood pressure, and by diseases such as diabetes. Atherosclerosis is a type of arteriosclerosis that affects only the inner lining of an artery.It is characterized by plaque deposits that block the flow of blood. Plaque is made of fatty substances, cholesterol, waste products from the cells, calcium, and fibrin, a stringy material that helps clot blood.rteriosclerosis is a broad term that includes a hardening of the inner and middle layers of the artery. It can be caused by normal aging, by high blood pressure, and by diseases such as diabetes. Atherosclerosis is a type of arteriosclerosis that affects only the inner lining of an artery.
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ACE gene The ACE gene provides instructions for making the angiotensin-converting enzyme. This enzyme is able to cut (cleave) proteins. It is part of the renin-angiotensin system, which regulates blood pressure and the balance of fluids and salts in the body.
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Atherosclerosis Atherosclerosis. Atherosclerosis is a disease in which plaque builds up inside your arteries. Arteries are blood vessels that carry oxygen-rich blood to your heart and other parts of your body.Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries.This limits the flow of oxygen-rich blood to your organs and other parts of your body. Atherosclerosis can lead to serious problems, including heart attack, stroke, or even death.rteries are blood vessels that carry oxygen-rich blood to your heart and other parts of your body. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries.
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Atherosclerosis Atherosclerosis is a disease in which plaque builds up inside your arteries. Arteries are blood vessels that carry oxygen-rich blood to your heart and other parts of your body. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood.Over time, plaque hardens and narrows your arteries.oronary Heart Disease. Coronary heart disease (CHD), also called coronary artery disease, occurs when plaque builds up in the coronary arteries. These arteries supply oxygen-rich blood to your heart. Plaque narrows the coronary arteries and reduces blood flow to your heart muscle.
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Loss of Arterial Elasticity May Accelerate Heart Disease Any disruption of the protein may lead to atherosclerosis by causing growth of smooth muscle cells beneath the arterial wall, Keating notes. Such disruptions could be caused by the stress of high blood pressure or the buildup of cholesterol-rich plaques, which cause inflammation within blood vessels.
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What is Atherosclerosis? Causes of Atherosclerosis: see causes of Atherosclerosis. Causes of Atherosclerosis: It is characterized by a narrowing of the arteries caused by cholesterol-rich plaques of immune system cells (Source: Genes and Disease by the National Center for Biotechnology). Risk factors for Atherosclerosis: see risk factors for Atherosclerosis.
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- Moreover, as the onset of neurogenic hypertension and cerebral atherosclerosis are associated with age (about 35 years), these clinical findings suggest that in the pathogenesis of atherosclerosis, there exist a primary factor and a secondary factor. 10 In my opinion, the primary factor is the main cause of atherosclerosis during the first decades of life; mechanical stresses generated by blood flow provoke a reactive biological response of the intima, ie, atherosclerotic changes.
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Atherosclerosis Atherosclerosis is a narrowing of the arteries caused by a buildup of plaque. It’s also called arteriosclerosis or hardening of the arteries. Arteries are the blood vessels that carry oxygen and nutrients from your heart to the rest of your body. As you get older, fat and cholesterol can collect in your arteries and form plaque. The buildup of plaque makes it difficult for blood to flow through your arteries.
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How Can Diabetes Cause Atherosclerosis? Atherosclerosis is a form of hardening of the blood vessels, caused by fatty deposits and local tissue reaction in the walls of the arteries.Blood supply beyond the affected parts of the artery is usually compromised by the narrowing and, sometimes, occlusion of the artery.he deposits, called plaques, may rupture with disastrous consequences. Diabetes mellitus is a documented high risk factor for the development of atherosclerosis. Heart disease and stroke, arising mainly from the effects of atherosclerosis, account for 65 percent of deaths among diabetics.
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- Mutations in the APOB, LDLR, LDLRAP1, and PCSK9 genes cause hypercholesterolemia. High blood cholesterol levels typically result from a combination of genetic and environmental risk factors. Lifestyle choices including diet, exercise, and tobacco smoking strongly influence the amount of cholesterol in the blood.
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Atherosclerosis Atherosclerosis is a narrowing of the arteries caused by a buildup of plaque. It’s also called arteriosclerosis or hardening of the arteries. Arteries are the blood vessels that carry oxygen and nutrients from your heart to the rest of your body. As you get older, fat and cholesterol can collect in your arteries and form plaque.
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Cause and Mechanisms of Intracranial Atherosclerosis Intracranial atherosclerosis, one of the leading causes of ischemic stroke, is associated with an increased risk for recurrent stroke and dementia. Individuals of Asian, Hispanic, and African American ancestry are especially affected.
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Atherosclerosis Atherosclerosis is a disease in which plaque builds up on the insides of your arteries. Arteries are blood vessels that carry oxygen-rich blood to your heart and other parts of your body. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries.
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WELCOME!Letâs Stay Connected. Sign-Up to receive breaking rare disease information, news and stories right to your inbox! (We value your privacy. Your email address will not be shared.)SIGN ME UP Mutations in the ACADVL gene cause VLCAD deficiency. This gene provides instructions for making an enzyme called very long-chain acyl-CoA dehydrogenase, which is required to break down (metabolize) a group of fats called very long-chain fatty acids. These fatty acids are found in foods and the body's fat tissues.
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Genes Linked to High Blood Pressure May 11, 2009 - A group of genes may raise the risks associated with high blood pressure, such as heart attack and stroke. Researchers found that 10 genetic variants individually explained about 1% of blood pressure variation after accounting for other risk factors, like age, gender, and excess weight.he prevalence of high blood pressure among the participants also increased as the number of implicated genetic variants increased. Researchers found that people who had very few of the associated blood pressure genes had blood pressure levels that were several mmHg lower than those with multiple variants.
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Atherosclerosis atherosclerosis is a disease in which plaque builds up inside your arteries arteries are blood vessels that carry oxygen rich blood to your heart and other parts of your body plaque is made up of fat cholesterol calcium and other substances found in the blood over time plaque hardens and narrows your arteries
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- Several common variations in the SNCA gene have been found to increase the risk of multiple system atrophy, a progressive brain disorder that affects movement and balance and disrupts the function of the autonomic nervous system.everal common variations in the SNCA gene have been found to increase the risk of multiple system atrophy, a progressive brain disorder that affects movement and balance and disrupts the function of the autonomic nervous system.