is afatinib chemotherapy
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- In the afatinib group, the most common treatment-related adverse events were diarrhea, rash/acne, and stomatitis; in the chemotherapy group, they were nausea, fatigue, and decreased appetite. Patient-reported outcomes favored afatinib, with better control of cough, dyspnea, and pain, the investigators say.
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- The most common chemotherapy drugs used to treat colorectal cancer are: 1  5-fluorouracil (5-FU, Adrucil). 2  given by intravenous intravenousWithin or into a vein (a blood vessel that carries blood from tissues and organs in the body to the heart). 3  capecitabine(Xeloda). 4  this is an oral form of 5-FU that is taken by mouth. 5  irinotecan (Camptosar, CPT-11).
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- Glivec (imatinib), which is known as Gleevec in the United States, is a cancer treatment indicated for: 1  Adult and pediatric patients with newly diagnosed Philadelphia chromosome (bcr–abl) positive (Ph+) Chronic Myeloid Leukemia for whom bone marrow transplantation is not considered as the first line of treatment.
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Avastin Â®  (bevacizumab) Platinum-Resistant Ovarian Cancer (prOC) Avastin, in combination with paclitaxel, pegylated liposomal doxorubicin or topotecan, is approved to treat platinum-resistant recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer in women who received no more than two prior chemotherapy treatments.
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Chemotherapy for Pancreatic Cancer Although pancreatic cancer has been classed as a tumour that is largely resistant to chemotherapy, 5-fluorouracil (5-FU) and 5-FU-based combination regimens have been shown to be superior to observation alone or no treatment arms in adjuvant trials, and to best supportive care in palliative therapy trials (Table 1).ancreatic cancer is a common, highly lethal disease that is rising in incidence. Chemotherapy based on 5-fluorouracil (5-FU) has been shown to prolong survival in advanced pancreatic cancer. Gemcitabine improves major symptoms and survival outcomes compared with bolus 5-FU.
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Neulasta This is not a chemotherapy drug. This medication is usually given at least 24 hours after chemotherapy to stimulate the growth of new, healthy, white blood cells (WBC). Pegfilgrastim is a longer acting form of filgrastim and the manufacturer recommends that it should not be given within 14 days prior to chemotherapy.
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Paclitaxel Protein-Bound Generic Name: Paclitaxel protein-bound. Drug Type: Abraxane is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. Abraxane is classified as an plant alkaloid, a taxane and an antimicrotubule agent. (For more detail, see How Abraxane Works section below.) What Abraxane Is Used For: Abraxane is used to treat breast cancer after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy. Prior therapy should have included an anthracycline chemotherapy unless clinically not appropriate.
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- This study has been completed. The goal of the Phase I part of this clinical research study is to find the highest tolerable dose of a combination of dasatinib, cetuximab, and FOLFOX (5-fluorouracil [5-FU], leucovorin [LV], and Eloxatin [oxaliplatin]) that can be given to patients with metastatic colorectal cancer. The safety of these drugs in combination will also be studied.
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Trastuzumab A 2014 Cochrane Review examined the safety and efficacy of trastuzumab-containing combination therapies (with chemotherapy, hormone blockers, or lapatinib) for the treatment of metastatic breast cancer. The overall hazard ratios for overall survival and progression free survival were 0.82 and 0.61 respectively. 2014 Cochrane Review examined the safety and efficacy of trastuzumab-containing combination therapies (with chemotherapy, hormone blockers, or lapatinib) for the treatment of metastatic breast cancer. The overall hazard ratios for overall survival and progression free survival were 0.82 and 0.61 respectively.
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- Currently, taxane-based chemotherapy schedules are a first-line treatment in both early-stage and metastatic breast cancer [3], the most common malignant tumor in women, occurring in one out of every eight women in her lifetime.
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- Afatinib is an oral, once daily targeted treatment which works by irreversibly blocking the ErbB family of receptors. The ERBB3 tyrosine kinase is activated by neuregulins (NRGs) or other ERBB and non-ERBB kinases and it connects to the downstream PI3K/AKT/ MAPK mitogenic pathway.
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- Although imatinib, a BCR-ABL tyrosine kinase inhibitor, is used to treat acute Philadelphia chromosome–positive (Ph +) leukemia, it does not prevent central nervous system (CNS) relapses resulting from poor drug penetration through the blood-brain barrier.entral nervous system (CNS) involvement is a relatively common complication in Philadelphia chromosome (Ph)–positive acute lymphoblastic leukemia (Ph + ALL) and blast crisis-chronic myelogenous leukemia (BC-CML).
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Is a DUI a Misdemeanor or a Felony? whether it is a misdemeanor dui or a felony dui the conviction will appear on your criminal record and will reflect badly on your character when you apply for a job try to rent or buy a place to live or in just about anything where a background check may be involved
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FDA Grants Genentechâs Cancer Immunotherapy Atezolizumab Priority Review for Advanced Bladder Cancer Atezolizumab was granted Priority Review designation based on results of the IMvigor 210 study, which showed the medicine shrank tumors in a type of advanced bladder cancer, and the majority responding to treatment continued to respond after nearly a year of follow up, said Sandra Horning, M.D., chief medical officer and head of Global Product ...
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Chemotherapy Medicines Depending on the characteristics of the cancer, a targeted therapy medicine, such as Herceptin (chemical name: trastuzumab), may be used in combination with some chemotherapy regimens. For example, the TCH regimen includes Taxotere, Herceptin, and carboplatin. Your doctor may talk about certain groups of chemotherapy medicines: 1  Anthracyclines are chemically similar to an antibiotic. Anthracyclines damage the genetic material of cancer cells, which makes the cells die. 2  Taxanes interfere with the way cancer cells divide. Taxol, Taxotere, and Abraxane are taxanes.
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A trial looking at ipilimumab and chemotherapy for small cell lung cancer (ICE) The chemotherapy drugs carboplatin and etoposide are often used to treat extensive small cell lung cancer. But the cancer can start to grow again. When this happens it is more difficult to treat. In this trial researchers looked at a drug called ipilimumab as well as chemotherapy. Ipilimumab is a type of biological therapy called a monoclonal antibody. It targets cancer cells by looking for a particular protein on the surface called CTLA-4. Ipilimumab stops CTLA-4 from switching off part of the immune system.
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- For a complete list, see your enrollment packet or call Customer Service.* * This is not a complete list of medications covered under your plan. This list represents certain common generic medications that are covered in full for HSA-qualified plans and is subject to change without prior notification.
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- What is amifostine? Amifostine a chemoprotectant (KEEM-o-pro-TEK-tant) that can help lessen the side effects of certain cancer chemotherapy medications or radiation treatment. Amifostine is used to protect the kidneys from harmful effects caused by cisplatin when given to patients with ovarian cancer. Amifostine is also used to prevent severe dry mouth caused by radiation treatment of the head and neck, which can affect the salivary gland. Amifostine will not prevent all side effects of chemotherapy medications. However, this medication may help protect your body from some of the serious side effects that chemotherapy can cause. Amifostine may also be used for purposes not listed in this medication guide.
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Basal Cell Carcinoma Imiquimod Imiquimod (Aldara) is an immune system booster available in a 5% cream that is FDA-approved for the treatment of genital warts, actinic keratoses (pre-cancers of the skin) and superficial basal cell carcinomas (common skin cancers).
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Melphalan The normal cells most commonly affected by chemotherapy are the blood cells, the cells in the mouth, stomach and bowel, and the hair follicles; resulting in low blood counts, mouth sores, nausea, diarrhea, and/or hair loss. Different drugs may affect different parts of the body.isplatin is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. Cisplatin is classified as an alkylating agent. (For more detail, see How Cisplatin Works section below).
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- If you have advanced pancreatic cancer, your doctor may suggest chemotherapy. The chemotherapy won't cure the cancer but it might shrink your cancer and so help to relieve some of the symptoms. It may help to slow down the growth of the cancer for a while.But chemotherapy doesn't help everyone with pancreatic cancer.OLFIRINOX combination chemotherapy. For advanced pancreatic cancer, doctors may use a combination of the chemotherapy drugs fluorouracil, irinotecan and oxaliplatin (FOLFIRINOX). You have these drugs every 2 weeks through a drip into a vein.
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Lung Cancer - Non-Small Cell Chemotherapy Drugs and Regimens. Most chemotherapy regimens use platinum compounds, either cisplatin (Platinol) or carboplatin (Paraplatin). The preferred regimen uses two drugs -- one of which is a platinum-based drug. Combinations may include paclitaxel (Taxol) and carboplatin or cisplatin.
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Efudex Efudex is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug.Efudex is classified as an antimetabolite.. (For more detail, see How Efudex Works section below). Efudex side effects are almost always reversible and will go away after treatment is complete. 2  There are many options to help minimize or prevent Efudex side effects. 3  There is no relationship between the presence or severity of Efudex side effects and the effectiveness of the medication.
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- Chemotherapy drugs. The most common chemotherapy drugs used to treat colorectal cancer are: 1  5-fluorouracil (5-FU, Adrucil). 2  given by intravenous intravenousWithin or into a vein (a blood vessel that carries blood from tissues and organs in the body to the heart). 3  injection, either intermittently or as a continuous infusion.
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- The following chemotherapy drugs may be included as part of the treatment regimen depending on the stage of pancreatic cancer: 1  S-1, a new chemotherapy oral agent, may replace gemcitabine (see below) as the most effective chemotherapeutic drug to treat pancreatic cancer.
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Chemotherapy for breast cancer 1 Adjuvant breast cancer chemotherapy: May be used after surgery or radiation therapy to eliminate any remaining cancer cells that may not have been removed during breast cancer surgery and/or radiation therapy. 2  It may also prevent the disease from spreading to other parts of the body.