what causes cystic fibrosis]
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A to Z List of Neurological Disorders 1 Cystic fibrosis primarily affects the lungs and digestive system. 2  It leads to the production of mucus that is much thicker and more sticky than usual. 3  Cystic fibrosis is a hereditary condition, caused by a defective gene. 4  The cystic fibrosis gene must be present in both parents for a child to have the condition.
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Cystic fibrosis Cystic fibrosis. Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections.
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Everything you need to know about cystic fibrosis Cystic fibrosis is a hereditary disease that causes the body to produce thick and sticky mucus that can clog the lungs and obstruct the pancreas.This genetic disease can be life threatening, and affects an estimated 30,000 children and adults in the US, with around 1,000 new cases diagnosed each year. Cystic fibrosis primarily affects the lungs and digestive system. 2  It leads to the production of mucus that is much thicker and more sticky than usual. 3  Cystic fibrosis is a hereditary condition, caused by a defective gene. 4  The cystic fibrosis gene must be present in both parents for a child to have the condition.
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Cystic Fibrosis Cystic fibrosis (CF) is an inherited life-threatening disease that affects many organs. It causes changes in the electrolyte transport system which causes cells to absorb too much sodium and water. CF is characterized by problems in the glands that produce sweat and mucus.
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Cystic fibrosis CF is caused by a mutation in the gene cystic fibrosis transmembrane conductance regulator (CFTR). The most common mutation, δF508, is a deletion (δ signifying deletion) of three nucleotides that results in a loss of the amino acid phenylalanine (F) at the 508th position on the protein.t is caused by the presence of mutations in both copies of the gene for the protein cystic fibrosis transmembrane conductance regulator (CFTR). Those with a single working copy are carriers and otherwise mostly normal.
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Understanding Cystic Fibrosis: The Basics Cystic fibrosis is an inherited disease. For someone to get cystic fibrosis, both parents must be carriers of the gene that causes it and then pass it on. That means 25% of the children of such parents will have cystic fibrosis.Boys and girls are equally likely to get the disease.About 10 million Americans carry the gene and do not know it.ystic fibrosis is a genetic disease, meaning it is caused by a person's genes. It affects the glands that produce mucus and sweat, causing mucus to become thick and sticky. As the mucus builds up, it can block airways in the lungs. This makes it increasingly difficult to breathe.
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Cystic fibrosis Cystic fibrosis. Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.[1][5] Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections.
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Overview Causes. In cystic fibrosis, a defect (mutation) in a gene changes a protein that regulates the movement of salt in and out of cells. The result is thick, sticky mucus in the respiratory, digestive and reproductive systems, as well as increased salt in sweat.Many different defects can occur in the gene.auses. In cystic fibrosis, a defect (mutation) in a gene changes a protein that regulates the movement of salt in and out of cells. The result is thick, sticky mucus in the respiratory, digestive and reproductive systems, as well as increased salt in sweat. Many different defects can occur in the gene.
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Cystic Fibrosis A defect in the CFTR gene causes cystic fibrosis (CF). This gene makes a protein that controls the movement of salt and water in and out of your body's cells. In people who have CF, the gene makes a protein that doesn't work well.This causes thick, sticky mucus and very salty sweat. Research suggests that the CFTR protein also affects the body in other ways. This may help explain other symptoms and complications of CF.More than a thousand known defects can affect the CFTR gene.The type of defect you or your child has may affect the severity of CF.n people who have CF, the gene makes a protein that doesn't work well. This causes thick, sticky mucus and very salty sweat. Research suggests that the CFTR protein also affects the body in other ways. This may help explain other symptoms and complications of CF.
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Cystic Fibrosis: Prenatal Screening and Diagnosis Cystic fibrosis is a genetic disorder caused by a gene that is passed from parent to child. It takes two genes—one from the mother and one from the father—for a person to have CF. If a person has only one copy of a gene for CF, he or she is known as a carrier.
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Cystic fibrosis It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Those with a single working copy are carriers and otherwise mostly normal. CFTR is involved in production of sweat, digestive fluids, and mucus.
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cystic fibrosis Cystic fibrosis affects the body's ability to move salt and water in and out of cells. This defect causes the lungs and pancreas to secrete abnormally thick mucus that blocks passageways and prevents proper function.
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- Cystic fibrosis is a genetic condition caused by a faulty gene (known as the CFTR gene). The CFTR gene normally creates a protein that moves salt and water out of a cell.If the CFTR gene is defective, it results in a build-up of thick, sticky mucus in the body's tubes and passageways.These blockages damage the lungs, digestive system and other organs, resulting in inflammation (swelling) and, in the lungs, repeated infections.f the CFTR gene is defective, it results in a build-up of thick, sticky mucus in the body's tubes and passageways. These blockages damage the lungs, digestive system and other organs, resulting in inflammation (swelling) and, in the lungs, repeated infections.
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Cystic fibrosis Cystic fibrosis is an inherited disease characterized by the buildup of thick, sticky mucus that can damage many of the body's organs. The disorder's most common signs and symptoms include progressive damage to the respiratory system and chronic digestive system problems.
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- Cystic fibrosis occurs when someone inherits a mutant form of a key gene present in the lungs and in many other tissues—the gene CFTR, which is an acronym for cystic fibrosis transmembrane conductance regulator, a protein that was discovered in the late 1980s.
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Cystic Fibrosis (CF) Cystic Fibrosis (CF) is an inherited disease that causes thickened mucus to form in the lungs, pancreas and other organs. In the lungs, this mucus blocks the airways, causing lung damage and making it hard to breathe.
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Mutations 2. Deletion of one codon causing Cystic Fibrosis. Cystic fibrosis is caused by a mutation in the Cystic Fibrosis Trans-membrane Regulator (CFTR) gene. This gene. Produces a trans-membrane protein that regulates the flow of chloride ions into the cells.
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Cystic Fibrosis A defect in the CFTR gene causes cystic fibrosis (CF). This gene makes a protein that controls the movement of salt and water in and out of your body's cells. In people who have CF, the gene makes a protein that doesn't work well.This causes thick, sticky mucus and very salty sweat. Research suggests that the CFTR protein also affects the body in other ways. This may help explain other symptoms and complications of CF.n people who have CF, the gene makes a protein that doesn't work well. This causes thick, sticky mucus and very salty sweat. Research suggests that the CFTR protein also affects the body in other ways. This may help explain other symptoms and complications of CF.
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Cystic Fibrosis - Topic Overview The life expectancy for people with cystic fibrosis has been steadily increasing. What causes cystic fibrosis? Cystic fibrosis is one of the most common genetic disorders in white children in the United States and Canada. It's caused by a change, or mutation, in a gene. The changed gene is passed down in families.
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Overview Cystic fibrosis is an inherited disorder that causes severe damage to the lungs and digestive system. Cystic fibrosis affects the cells that produce mucus, sweat and digestive juices. These secreted fluids are normally thin and slippery.But in people with cystic fibrosis, a defective gene causes the secretions to become thick and sticky.Instead of acting as a lubricant, the secretions plug up tubes, ducts and passageways, especially in the lungs and pancreas.ystic fibrosis is an inherited disorder that causes severe damage to the lungs and digestive system. Cystic fibrosis affects the cells that produce mucus, sweat and digestive juices. These secreted fluids are normally thin and slippery.
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Cystic Fibrosis - Cause Cystic fibrosis occurs when a child inherits a changed (mutated) gene from both parents. The changed gene causes problems with the way salt and water move in and out of the cells that make mucus, causing the mucus to be thick and sticky. This kind of mucus makes it hard for the body to keep certain organs clean and healthy. Many people don't know they have the changed gene.
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- 1 Cystic fibrosis primarily affects the lungs and digestive system. 2  It leads to the production of mucus that is much thicker and more sticky than usual. 3  Cystic fibrosis is a hereditary condition, caused by a defective gene. 4  The cystic fibrosis gene must be present in both parents for a child to have the condition. It leads to the production of mucus that is much thicker and more sticky than usual. 2  Cystic fibrosis is a hereditary condition, caused by a defective gene. 3  The cystic fibrosis gene must be present in both parents for a child to have the condition.
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What is cystic fibrosis and how do you get it? Cystic fibrosis is a genetic disorder in which certain proteins in the lungs are not functioning properly - you get it from inheriting the genes for the disease from your parents. The malfunctioning proteins result in accumulations of thick, sticky mucus in the lungs which must be coughed up regularly.
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- Cystic fibrosis (CF) is a genetic disorder. It is caused by an abnormal gene that is passed from parent to child. It is a lifelong illness that affects all of the organs of the body and often causes problems with digestion and breathing.
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- cystic fibrosis. Cystic fibrosis (CF) is an inherited disease that affects the lungs, digestive system, sweat glands, and male fertility. Its name derives from the fibrous scar tissue that develops in the pancreas, one of the principal organs affected by the disease.
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What Causes CF Cystic fibrosis occurs because of mutations in the gene that makes a protein called CFTR (cystic fibrosis transmembrane regulator). A person with CF produces abnormal CFTR protein-or no CFTR protein at all, which causes the body to make thick, sticky mucus instead of the thin, watery kind.Cystic Fibrosis affects both males and females, but is not contagious to healthy individuals.Cystic fibrosis is an inherited disease caused by mutations (changes) in a gene on chromosome 7, one of the 23 pairs of chromosomes that children inherit from their parents.Humans have 23 pairs of chromosomes in their DNA. The CF gene is found on chromosome number 7. person with CF produces abnormal CFTR protein-or no CFTR protein at all, which causes the body to make thick, sticky mucus instead of the thin, watery kind. Cystic Fibrosis affects both males and females, but is not contagious to healthy individuals.