most common drugs that cause aplastic anemia
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- Chemicals used in insecticides (chlorophe-. nothane), glue (toluene), and Stoddard solvent. (petroleum distillates) have also been associated with. aplastic anemia. Drugs. Chloramphenicol was, at one point, the most. common cause of drug-induced aplastic anemia in the. United States. Anticonvulsant medications, in particular. carbamazepine and hydantoins, are also associated with. the development of aplastic anemia.
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Anemia Anemia and Pregnancy - Learn about the risk factors and symptoms of anemia during pregnancy. Aplastic anemia is a rare form of anemia that occurs when the body stops making enough red blood cells. Common causes include viral infections, exposure to toxic chemicals, drugs, and autoimmune diseases. Idiopathic aplastic anemia is the term used when the reason for low red blood cell production is not known. Hemolytic anemia occurs when red blood cells are broken up in the bloodstream or in the spleen.
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The seven types of anaemia The most common symptoms of aplastic anaemia are. 1  Fatigue. 2  Shortness of breath. 3  Dizziness. Headache.  Coldness in your hands or 1  feet. Pale skin, gums and nail 2  beds. Chest  pains.
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- Overall, the most common symptoms of aplastic anemia include: 1  Significant fatigue or weakness. 2  Bruising or bleeding easily. 3  Shortness of breath.  Recurring infections and/or flu-like 1  symptoms. The appearance of small red dots on the skin that indicates bleeding under the skin. 2  Headache. Fever due to infection.
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Myelophthisic anemia The presence of immature blood cell precursors helps distinguish another cause of pancytopenia, aplastic anemia, from myelophthisic anemia because in aplastic anemia the hematopoietic cells are damaged and immature blood cells are not seen in the peripheral blood.
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Top 20 Doctor insights on: Neglis Aplastic Anemia Symptoms Low blood counts: Aplastic anemia is a bone marrow failure disease. It leads to low white blood cells, red blood cells and platelets. Symptoms can include fatigue, increased risk of infection, bleeding, easy bruising, shortness of breath. It is a life-threatening illness that needs to be treated quickly.
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Secondary Aplastic Anemia Anemia - secondary aplastic; Acquired aplastic anemia. Secondary aplastic anemia is caused by injury to blood stem cells. Normal blood stem cells divide and turn into all blood cell types, mainly white blood cells, red blood cells, and platelets. When blood stem cells are injured, there is a reduction in all blood cell types.
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- The following categories of drugs are known to cause macrocytosis: 1  Folate antagonists (eg, methotrexate 2  ) Purine antagonists (eg, 6-mercaptopurine [6-MP]) 3  Pyrimidine antagonists (eg, cytosine arabinoside [ara-C]) 4  Alkylating agents (eg, cyclophosphamide) 5  Tyrosine kinase inhibitors (eg, sunitinib, and imatinib) 6  Zidovudine (AZT) 7  Trimethoprim.
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Aplastic Anemia About Aplastic Anemia. Aplastic anemia is the medical term for bone marrow failure. We treat patients with aplastic anemia at our Bone Marrow Failures Disorders Program at the Johns Hopkins Kimmel Cancer Center. The bone marrow, a spongy tissue inside the bones, is the factory for all blood cell lines -- red cells, white cells, and platelets.
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Felbatol Aplastic Anemia. THE USE OF FELBATOL® (felbamate) IS ASSOCIATED WITH A MARKED INCREASE IN THE INCIDENCE OF APLASTIC ANEMIA. ACCORDINGLY, FELBATOL® SHOULD ONLY BE USED IN PATIENTS WHOSE EPILEPSY IS SO SEVERE THAT THE RISK OF APLASTIC ANEMIA IS DEEMED ACCEPTABLE IN LIGHT OF THE BENEFITS CONFERRED BY ITS USE (SEE INDICATIONS).
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Aplastic anemia Aplastic anemia. Aplastic anemia is a rare disease in which the bone marrow and the hematopoietic stem cells that reside there are damaged. This causes a deficiency of all three blood cell types (pancytopenia): red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia). Aplastic refers to inability of the stem cells to generate mature blood cells.
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Idiopathic Aplastic Anemia In people with aplastic anemia, this process is disrupted. Stem cells are damaged and too few blood cells are made. Numerous conditions can damage your bone marrow. In people with idiopathic aplastic anemia, the cause of that damage is unknown.
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Aplastic Anemia Causes 1 A viral infection. In some people, aplastic anemia may be related to a viral infection that affects the bone marrow.  Pregnancy. Aplastic anemia may occur in pregnancy, but this is rare. It may be related to an autoimmune problem - the body's immune system begins attacking the bone marrow during pregnancy.
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- Each year, between 600 and 900 people in the U.S. are diagnosed with aplastic anemia. It is generally considered to have no known cause, but is sometimes the result of an autoimmune disorder in which white blood cells attach the bone marrow.
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Anemia If you appear to have a form of aplastic anemia, your doctor may refer you to a hematologist for a bone marrow biopsy to determine the cause of the anemia. Medications and blood transfusions may be used to treat aplastic anemia. Hemolytic anemia occurs when red blood cells are destroyed in the blood stream.
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- Anemia Drugs: Darbepoetin Alfa, Epoetin Alfa, and Methoxy Polyethylene Glycol-Epoetin Beta Page 1 of 14. UnitedHealthcare Commercial Drug Policy Effective 10/01/2016. Proprietary Information of UnitedHealthcare. Copyright 2016 United HealthCare Services, Inc. Anemia Drugs: Darbepoetin Alfa, Epoetin Alfa, and Methoxy.
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Aplastic Anemia People with aplastic anemia have low levels of all three types of blood cells that are normally manufactured in the bone marrow. Aplastic anemia is a problem with cells in the bone marrow called stem cells. Stem cells are the basic mother cells that develop into the three types of blood cells. In aplastic anemia, something either destroys the stem cells or drastically changes the environment of the bone marrow so that the stem cells can't develop properly. Several factors can cause this problem, including:
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Aplastic Anemia Aplastic anemia occurs when your bone marrow doesn’t make enough red and white blood cells, and platelets. A reduced number of red blood cells causes hemoglobin to drop. Hemoglobin is the part of blood that carries oxygen through the body. A reduced number of white blood cells makes you more prone to infection.
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busulfan - injection, Busulfex Drugs & Medications. hydroxyurea. This medication decreases bone marrow function, an effect that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, or cause you to bruise or bleed more easily.
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Alone we are rare. Together we are strong.â¥ Donate Today In acquired aplastic anemia, an almost complete absence of hematopoietic stem cells eventually results in low levels of red and white blood cells and platelets (pancytopenia). Specific symptoms associated with acquired aplastic anemia may vary, but include fatigue, chronic infections, dizziness, weakness, headaches, and episodes of excessive bleeding.
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Aplastic Anemia Treatment & Management Infections are a major cause of mortality in patients with aplastic anemia.Risk factors include prolonged neutropenia and the indwelling catheters used for specific therapy. Fungal infections, especially those due to Aspergillus species, pose a major risk. Patients should maintain hygiene to reduce infection risk.
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Chlorambucil Bone marrow suppression (anemia, neutropenia, thrombocytopenia) is the most commonly occurring side effect of chlorambucil. Withdrawn from the drug, this side effect is typically reversible. Like many alkylating agents, chlorambucil has been associated with the development of other forms of cancer.
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Aplastic anemia Treatments for Aplastic anemia. 1  Varies depending on underlying cause but possible therapies include: blood transfusion, oxygen administration, bone marrow-stimulating agents, bone marrow transplant and immunosuppressive drugs if condition is caused by malfunctioning immune system. 2  more treatments...».