what is botulinum toxin
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Overview Botulinum toxin (abbreviated either as BTX or BoNT) is produced by Clostridium botulinum, a gram-positive anaerobic bacterium. The clinical syndrome of botulism can occur following ingestion of contaminated food, from colonization of the infant gastrointestinal tract, or from a wound infection.
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All About Bacteria Clostridium botulinum is an anaerobic, rod-shaped sporeforming bacterium that produces a protein with characteristic neurotoxicity. Under certain conditions, these organisms may grow in foods producing toxin(s). Botulism, a severe form of food poisoning results when the toxin-containing foods are ingested.otulism in infants 6 weeks to 1 year of age was first recognized as a distinct clinical entity in 1976. This form of botulism results from growth and toxin production by C. botulinum within the intestinal tract of infants rather than from ingestion of a food with preformed toxin.
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Overview Botulism is a rare but serious condition caused by toxins from bacteria called Clostridium botulinum. Three common forms of botulism are: Foodborne botulism. The harmful bacteria thrive and produce the toxin in environments with little oxygen, such as in canned food. Wound botulism.
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Everything you need to know about Botox 1 Botox is the most popular cosmetic surgery treatment, with more than 6 million Botox treatments administered each year. 2  Botox is a neurotoxin derived from Clostridium botulinum, an organism found in the natural environment where it is largely inactive and non-toxic. Botox is a neurotoxin derived from Clostridium botulinum, an organism found in the natural environment where it is largely inactive and non-toxic. 2  Botulinum toxin is used to reduce fine lines and wrinkles by paralysing the underlying muscles.
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BOTULINUM TOXIN Introduction. Botulinum toxin, also called “miracle poison,” is one of the most poisonous biological substances known.[ 1 ] It is a neurotoxin produced by the bacterium Clostridium botulinum, an anaerobic, gram-positive, spore-forming rod commonly found on plants, in soil, water and the intestinal tracts of animals.otulinum toxin, one of the most poisonous biological substances known, is a neurotoxin produced by the bacterium Clostridium botulinum. C. botulinum elaborates eight antigenically distinguishable exotoxins (A, B, C 1, C 2, D, E, F and G).
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Botulinum toxin Infection with the bacterium causes the disease botulism. The toxin is also used commercially in medicine, cosmetics, and research. Botulinum is the most acutely lethal toxin known, with an estimated human median lethal dose (LD50) of 1.3–2.1 ng/kg intravenously or intramuscularly and 10–13 ng/kg when inhaled.
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Botulism Botulism is a serious illness that causes flaccid paralysis of muscles. It is caused by a neurotoxin, generically called botulinum toxin, produced by the bacterium Clostridium botulinum (and rarely by C. butyricum and C. baratii).otulism facts. 1  The botulism neurotoxin is one of the most potent, lethal substances known. 2  Botulism is a disease caused by this neurotoxin (specifically A, B, E, or F type neurotoxin). 3  The neurotoxin is produced by bacteria called Clostridium botulinum. 4  The neurotoxin paralyzes muscles and can be deadly.
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Botulism Botulism, also known as botulinus intoxication is a serious illness that causes paralysis, caused by the botulinum toxin. The toxin is caused by Clostridium botulinum, a type of bacterium.There are four ways in which the toxin can enter the human body: All types of botulism eventually lead to paralysis, which generally starts with the face muscles and then spreads to the limbs. Adult botulism-by colonization of the digestive tract by Clostridium botulinum in adults. 2  Foodborne botulism-as a result of eating foodstuffs with the toxin. 3  Wound botulism-when botulinum toxin contaminates a wound.
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Preventing Foodborne Illness: Clostridium botulinum 1 Clostridium botulinum is ubiquitous in nature, often found in soil and water. Although the bacteria and spores alone do not cause disease, their production of botulinum toxin renders them pathogenic. Botulinum toxin is a neurotoxin that causes botulism, a serious paralytic condition that can lead to death. There are seven strains of C. botulinum, each distinguished by its production of a serologically distinct botulinum type (CDC 2014).
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FAQs Botulism in the Great Lakes Botulism is a serious neuromuscular illness caused by a toxin that is produced by the bacterium Clostridium botulinum. Avian botulism has been recognized as a major cause of mortality in migratory birds since the 1900s. Human botulism is typically caused by eating improperly canned or stored foods. The bacterium is classified into 7 types (A-G) by characteristics of the neurotoxins that are produced.
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Botulism Botulinum Toxin. Botulism is an intoxication caused by botulinum toxin, which is produced by Clostridium botulinum and, rarely, by other Clostridium species. Seven antigenically distinct toxin types (A, B, C, D, E, F, G) have been identified.ound Botulism. 1  Wound botulism is caused by infection of a contaminated wound with C botulinum and subsequent absorption into the circulation of locally produced toxin. 2  C botulinum is a natural contaminant of soil throughout the United States (Smith 1978).
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Publications Botulism is a rare but serious paralytic illness caused by a nerve toxin produced by the bacterium Clostridium botulinum (klos-trih-dee-um bot-u-li-num) . Human botulism is mainly caused by four of the seven recognized types of Clostridium botulinum bacteria: types A, E, rarely F and possibly G.hese are all symptoms of muscle paralysis caused by the bacterial toxin. If untreated, these symptoms may progress to paralysis of the neck, arms, respiratory muscles, torso and legs. Infants with botulism appear lethargic, feed poorly, are constipated, have a weak cry and exhibit poor muscle tone.
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Botulism Botulism is a rare and potentially fatal illness caused by a toxin, produced by the bacterium Clostridium botulinum. The disease begins with weakness, trouble seeing, feeling tired, and trouble speaking. This may then be followed by weakness of the arms, chest muscles, and legs. The disease does not usually affect consciousness or cause a fever. Botulism can be spread several different ways. The bacterial spores which cause it are common in both soil and water. They produce the botulinum toxin when exposed to low oxygen levels and certain temperatures. Foodborne botulism happens when food containing the toxin is eaten.
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Botox: What You Need to Know Botox® is a trade name for botulinum toxin A. In this way, Botox® is related to botulism. Botulism is a form of food poisoning that occurs when someone eats something containing a neurotoxin produced by the bacterium Clostridium botulinum.Botulinum toxin A is one of the neurotoxins produced by Clostridium botulinum. Botulism-Food poisoning usually caused by ingesting the neurotoxin produced by the bacterium Clostridium botulinum; characterized by paralysis; can be fatal. 2  Blepharospasm-Involuntary spasmodic contraction of certain eye muscles. 3  Cervical dystonia-Dystonia of the neck area.
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- Medical Definition of BOTULISM. : acute food poisoning caused by botulinum toxin produced in food by a bacterium of the genus Clostridium (C. botulinum) and characterized by muscle weakness and paralysis, disturbances of vision, swallowing, and speech, and a high mortality rate—see botulinum toxin, limberneck.edical Definition of BOTULISM. : acute food poisoning caused by botulinum toxin produced in food by a bacterium of the genus Clostridium (C. botulinum) and characterized by muscle weakness and paralysis, disturbances of vision, swallowing, and speech, and a high mortality rate—see botulinum toxin, limberneck.
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- Botox is a drug made from a neurotoxin produced by the bacterium Clostridium botulinum called botulinum toxin. It is used medically to treat certain muscular conditions and cosmetically remove wrinkles by temporarily paralyzing muscles.
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Cosmetic Procedures and Botox Introduction. Botox is a brand name of a toxin produced by the bacterium Clostridium botulinum. There are other brand names for botulinum, such as Xeomin. In large amounts, this toxin can cause botulism, which you probably associate with food poisoning.Despite the fact that one of the most serious complications of botulism is paralysis, scientists have discovered a way to use it to human advantage.otox is a brand name of a toxin produced by the bacterium Clostridium botulinum. There are other brand names for botulinum, such as Xeomin.
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Botulism food poisoning Botulism. Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium Clostridium botulinum.otulism. Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium Clostridium botulinum.
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onabotulinumtoxinA What is onabotulinumtoxinA (Botox)? OnabotulinumtoxinA (Botox), also called botulinum toxin type A, is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity. Botox is used to treat cervical dystonia (severe spasms in the neck muscles), muscle spasms in the arms and hands, and severe underarm sweating (hyperhidrosis).
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Cause Botulism is caused by a toxin that affects nerves, and in that sense it is not an infectious disease. The botulism toxin is produced by the bacteria Clostridium botulinum, and is one of the deadliest known toxins. There are 7 different types of botulism toxin labeled A through F. Types C and E are most important in wild birds. While this toxin can also affect humans it is not a zoonotic disease.
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- Definition of BOTULINUM. : a spore-forming bacterium (Clostridium botulinum) that secretes botulinum toxin.— bot·u·li·nal \-ˈlī-nəl\ adjective. a spore-forming bacterium (Clostridium botulinum) that secretes botulinum toxin.
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Translation of Proteins Introduction. Botulism is a rare but potentially fatal condition caused by toxins produced by Clostridium botulinum bacteria.The toxins produced by C. botulinum are some of the most powerful toxins known to science.ntroduction. Botulism is a rare but potentially fatal condition caused by toxins produced by Clostridium botulinum bacteria.
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Clostridium botulinum C. botulinum is a diverse group of pathogenic bacteria initially grouped together by their ability to produce botulinum toxin and now known as four distinct groups, C. botulinum groups I-IV. C. botulinum groups I-IV, as well as some strains of Clostridium butyricum and Clostridium baratii, are the bacteria responsible for producing botulinum toxin.
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Botox Injections Botox Injections. Botulinum toxin, produced by the bacterium 'Clostridium botulinum' used to be best known as the substance that caused the illness 'botulism'. In 1992 a form of the toxin, known as Botulinum Toxin A, was described as being of use in the cosmetic setting.
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Botulism Botulism is a rare and potentially fatal illness caused by a toxin produced by the bacterium Clostridium botulinum. The disease begins with weakness, trouble seeing, feeling tired, and trouble speaking. This may then be followed by weakness of the arms, chest muscles, and legs.
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Botulinum toxin Acetylcholine release by nerve impulses can be blocked by botulinum toxin, a very potent chemical that is produced in food contaminated by the bacteria Clostridium botulinum and is an occasional cause of severe food poisoning (botulism). The most serious effect is paralysis of the skeletal muscle.