what is AXL protein
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- 1 The Axl protein is a member of a new family of receptor tyrosine kinases, which the ligand, Gas6, a protein S-related molecule, has recently been identified. 2  We previously clarified the expression of Axl and mitogenic action of Gas6 in thyroid carcinoma cells.AS6, the product of a growth arrest specific (GAS) gene, is the ligand of the tyrosine kinase receptor Axl. GAS6 and Axl are both expressed in endothelial cells, where they are involved in many processes such as leukocyte transmigration through capillaries and neointima formation in injured vessels.
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What is the ACL? What is the ACL? The ACL, or the Anterior Cruciate Ligament, is one of four main ligaments around the knee that connect the femur (thigh bone) to the tibia (shin bone). The ACL prevents the tibia from sliding forward on the femur, and provides stability to the knee with twisting or pivoting activities, such as playing basketball and soccer.
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- Silica is a naturally forming mineral found throughout the world and is the second most plentiful mineral on the earth. While it is plentiful, many individuals end up with deficiencies or problems relating to low silica in the body.
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- The ATXN2 gene provides instructions for making a protein called ataxin-2. This protein is found throughout the body, but its function is unknown.Ataxin-2 is found in the fluid inside cells (cytoplasm) and seems to interact with a cell structure called the endoplasmic reticulum.The endoplasmic reticulum is involved in protein production, processing, and transport. Researchers believe that ataxin-2 may be involved in processing RNA, a chemical cousin of DNA.taxin-2 is found in the fluid inside cells (cytoplasm) and seems to interact with a cell structure called the endoplasmic reticulum. The endoplasmic reticulum is involved in protein production, processing, and transport. Researchers believe that ataxin-2 may be involved in processing RNA, a chemical cousin of DNA.
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- In human anatomy, the axillary artery is a large blood vessel that conveys oxygenated blood to the lateral aspect of the thorax, the axilla and the upper limb. Its origin is at the lateral margin of the first rib, before which it is called the subclavian artery. After passing the lower margin of teres major it becomes the brachial artery.
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axonal ax·o·nal. Pertaining to an axon; most often used to describe the type of underlying nerve pathology responsible for generalized polyneuropathies. In this context, usually used incorrectly, that is, axonal polyneuropathy, rather than axon loss polyneuropathy (to distinguish the disorder from a demyelinating polyneuropathy).
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Human T-lymphotropic virus HTLV-I is an abbreviation for human T-cell lymphotropic virus type 1 , also called human T-cell leukemia type 1 , a virus that has been seriously implicated in several kinds of diseases , including HTLV-I-associated myelopathy , and as a virus cancer link for leukemia ( see adult T-cell leukemia / lymphoma ) .HTLV-1 has six reported subtypes ( ...
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Alpha-keratin Alpha-keratin , or α-keratin, is a type of keratin found in mammals. This protein is the primary component in hairs , horns , nails and the epidermis layer of the skin . α-keratin is a fibrous structural protein , meaning it is made up of amino acids that form a repeating secondary structure.
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National Spinal Cord Injury Association Resource Center Scientists have identified some proteins in the myelin sheath surrounding spinal cord axons which inhibit nerve cell growth. Additionally, other regeneration-inhibiting proteins have been identified on the surfaces of cells that form the nervous system equivalent of a scar.
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- Collagen is a fibrous protein found in vertebrates, the major element of skin, bone, tendon, cartilage, blood vessels and teeth. It forms insoluble fibers of high tensile strength and which contains the unusual amino acids hyroxyproline and hydroxylysine.atrix Collagen Catrix is a new collagen wound-healing powder that has been shown to be effective in the treatment of wounds healing by secondary intent such as pressure ulcers, venous stasis ulcers and diabetic ulcers as well as second-degree burns and post-radiation dermatitis.
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Diffuse large B-cell lymphoma Diffuse large B-cell lymphoma. Diffuse large B-cell lymphoma (DLBCL or DLBL) is a cancer of B cells, a type of white blood cell responsible for producing antibodies. It is the most common type of non-Hodgkin lymphoma among adults, with an annual incidence of 7–8 cases per 100,000 people per year.
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Axillary nerve From Wikipedia, the free encyclopedia. The axillary nerve or the circumflex nerve is a nerve of the human body, that originates from the brachial plexus (upper trunk, posterior division, posterior cord) at the level of the axilla (armpit) and carries nerve fibers from C5 and C6.tructure [edit]. The nerve lies at first behind the axillary artery, and in front of the subscapularis, and passes downward to the lower border of that muscle.
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Everything You Need To Know About Shirodhara According to Ayurveda, shirodhara is beneficial for Vata and Pitta dosha. When out of balance, Vata dosha exhibits as fear, insecurity, worry, racing thoughts. Out of balance Pitta dosha exhibits as anger, irritability, frustration, judgment.
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Axid Axid is a competitive, reversible inhibitor of histamine at the histamine H2-receptors, particularly those in the gastric parietal cells. Antisecretory Activity—1. Effects on Acid Secretion: Axid significantly inhibited nocturnal gastric acid secretion for up to 12 hours.
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Background Acute promyelocytic leukemia (APL) is a unique subtype of the acute leukemias. It has distinct cytogenetics, clinical features, and biologic characteristics. APL is caused by an arrest of leukocyte differentiation at the promyelocyte stage.
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Lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) is a substrate of cathepsin-F, a cysteine protease mutated in type-B-Kufs-disease 1. The lysosomal integral membrane protein type-2 (LIMP-2) is an abundant protein of the lysosomal membrane and has been identified as a mannose-6-phosphate-independent lysosomal transport receptor for β-glucocerebrosidase (GC) [1] .
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RELA Gene  (Protein Coding) RELA (RELA Proto-Oncogene, NF-KB Subunit) is a Protein Coding gene. Diseases associated with RELA include Ependymoma and Reticuloendotheliosis. Among its related pathways are RANK Signaling in Osteoclasts and AGE/RAGE pathway.
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Why is pot called pot? And now, when people talk about “pot,” they mean the dried leaves of marijuana or any other substance or drug that contains marijuana. Marijuana is sourced from the leaves and flowers of the hemp plant. The flowers and leaves are then dried for a variety of uses. Most marijuana is abused for its addictive and/or psychogenic effects. Many people have even become addicted because of the supposed “feel-good” effects of this particular substance.
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- Dermaxyl is scientifically known as Palmitoyl Oligopeptide, a tripeptide commonly found in animal tissues. Peptides, in general, are nothing but short chains of Amino Acids. Amino Acids, in turn, may be understood as the basic building blocks of proteins and other different types of organic molecules.
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MDACC Chapter 3 & 4 CLL and CML CLL is a clonal B-cell lymphoid leukemia. Morphologically, CLL cells resemble small mature lymphocytes arrested in an intermediate stage of the B-cell differentiation pathway. The hallmark of CLL cells are that they express CD5, an antigen commonly found on T cells.
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Neutrophil elastase Neutrophil elastase (EC 3.4.21.37, leukocyte elastase, ELANE, ELA2, elastase 2, neutrophil, elaszym, serine elastase) is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity. Secreted by neutrophils and macrophages during inflammation, it destroys bacteria and host tissue.eutrophil elastase hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils.
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- This new abnormal chromosome is known as the Philadelphia chromosome. The Philadelphia chromosome is found in the leukemia cells of almost all patients with CML. The swapping of DNA between the chromosomes leads to the formation of a new gene (an oncogene) called BCR-ABL.This gene then produces the BCR-ABL protein, which is the type of protein called a tyrosine kinase.This protein causes CML cells to grow and reproduce out of control. In a very small number of CML patients, the leukemia cells have the BCR-ABL oncogene but not the Philadelphia chromosome.It is thought that the BCR-ABL gene must form in a different way in these people.his new abnormal chromosome is known as the Philadelphia chromosome. The Philadelphia chromosome is found in the leukemia cells of almost all patients with CML. The swapping of DNA between the chromosomes leads to the formation of a new gene (an oncogene) called BCR-ABL.
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Introduction The anterior cruciate ligament (ACL) is a band of dense connective tissue which courses from the femur to the tibia.The ACL is a key structure in the knee joint, as it resists anterior tibial translation and rotational loads.he anterior cruciate ligament (ACL) is a band of dense connective tissue which courses from the femur to the tibia.
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Treatment of Philadelphia chromosomeâpositive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate Imatinib mesylate, an inhibitor of the Bcr-Abl tyrosine kinase, has modest activity in refractory/relapsed Philadelphia chromosome (Ph)-positive acute lymphocytic leukemia (ALL). Use of concurrent chemotherapy and imatinib mesylate in newly diagnosed Ph-positive ALL was explored.
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What Is The Anterior Cruciate Ligament? The anterior cruciate ligament (ACL) is one of the most important of four strong ligaments connecting the bones of the knee joint. It is often injured. Ligaments are strong, dense structures made of connective tissue that stabilize a joint. They connect bone to bone across the joint.
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ADAM10 gene From NCBI Gene: Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.