Antibodies to the ganglioside GD1b have been reported in various forms of immune-mediated neuropathy  but their clinical relevance for diagnosis and prognosis is unknown We investigated the prevalence of anti-GD1b antibodies in acute and chronic immune-mediated neuropathies  and the clinical presentation and outcome in Guillain-Barré syndrome (GBS) and Miller Fisher-GBS overlap syndrome (MF-GBS)