Pro-inflammatory cytokines secreted by macrophages and other cell types are implicated as intraovarian factors affecting different aspects of ovarian function including follicle and corpus luteum ‘turnover’  steroidogenesis and angiogenesis Here  we compared granulosal (GC) and thecal (TC) expression of TNF  IL6 and their receptors (TNFRSF1A  TNFRSF1B and IL6R) during bovine antral follicle development  all five mRNA transcripts were detected in both GC and TC and statistically significant cell-type and follicle stage-related differences were evident