Unable to publish in visual studio 2015
<p>Ever since installing Visual Studio 2015 Professional Update 3,</p>

<p><a href="https://www.visualstudio.com/en-us/news/releasenotes/vs2015-update3-vs" rel="nofollow noreferrer">https://www.visualstudio.com/en-us/news/releasenotes/vs2015-update3-vs</a></p>

<p>I am unable to publish to any target at all. I repeatedly get informed:</p>

<blockquote>
  <p>Could not load file or assembly 
  Microsoft.VisualStudio.ProjectSystem.DotNet.Internal - The system
  cannot find the file specified.</p>
</blockquote>

<p>Has anyone experienced the same issue and managed to resolve it?</p>

<p>I have repaired Visual Studio: No Success
I have reinstalled Visual Studio after deleting all files according to <a href="https://social.msdn.microsoft.com/Forums/vstudio/en-US/435656ba-49df-4af4-b501-27b568fdeae1/unable-to-publish-to-any-target?forum=visualstudiogeneral" rel="nofollow noreferrer">this link</a>, with no success</p>

<p>I have ensured that all updates have been applied to Visual Studio: No Success</p>

<p>Can someone please help me?</p>

<p>Asked in thread below is the installed version of -net and I have not installed anything besides windows  10 and visual studio 15. <a href="https://i.stack.imgur.com/wvtcP.png" rel="nofollow noreferrer"><img src="https://i.stack.imgur.com/wvtcP.png" alt="enter image description here"></a></p>