Aaron M.
Senior Data Engineer, Analytics
Bachelor of Science - BS
https://media-exp1.licdn.com/dms/image/C560BAQFsjvxBDYgQMA/company-logo_100_100/0/1565726655033?e=1655942400&v=beta&t=nXYi4hYyLXLohP0VBXG5NnI4QxWaww9NkbeK6pV-0ns
University of California, Santa Cruz
https://www.linkedin.com/school/ucsc/
Bachelor of Science - BS
https://media-exp1.licdn.com/dms/image/C560BAQFsjvxBDYgQMA/company-logo_100_100/0/1565726655033?e=1655942400&v=beta&t=nXYi4hYyLXLohP0VBXG5NnI4QxWaww9NkbeK6pV-0ns
University of California, Santa Cruz
https://www.linkedin.com/school/ucsc/
Analog Electronics (w/ lab)
EE 171/L
Bioengineering Project
BME 123A/B
Bioethics in the 21st Century: Science, Business, and Society
BME 80G
Computer Systems and Assembly Language (w/ lab)
CMPE 12/L
Computer Systems and C programming (with lab)
CMPE 13/L
Electromagnetic Fields and Waves (w/ lab)
EE 135/L
Introduction To Mechatronics (w/ lab)
CMPE 118/L
Introduction to BioMEMS (w/ project)
EE-212
Introduction to Probability Theory
AMS 131
Logic Design (w/ lab)
CMPE 100/L
Mechatronics (w/ lab)
CMPE-118/L
Molecular Biomechanics (w/ lab)
BME 150/L
Ordinary Differential Equations
MATH 24
Professional Practice in Bioengineering
BME 180
Properties of Materials (w/ lab)
EE 145/L
Protein Engineering Lab
BME 128L
Research Programming in the Life Sciences (w/ lab)
BME 160/L
Sensing and Sensor Technology w/Lab
CMPE-167/L
Synthetic Biology Mentored Research
BME 188A/B
Introduction:

It is well known that the occurrence of a codon in an organism has a direct effect on poly-peptide extension rate. By way of co-translational folding, we have a causal relationship between translation rate. This leads to the notion that an organism’s codon usage can be used to provide structural information about any given non-heterologous protein from said organism. In this study, we aim to use dynamic programming and HMMs to use an organism’s codon usage as guidance for alignment and protein structure prediction. Lastly, a more general aim was to observe the probability distribution of codon occurrence across all organisms to find out the usefulness of codon composition of CDS’ in making inferences about their respective translated protein structures.

Accomplishments

• First research done to answer the question: “ Can codon usage be used to align and predict Protein structures?” • Design of project approved by faculty of UCSC  Department of Biomolecular Engineering • Complete design of HMM for folding determination by codon usage • Successful HTML scraping for codon usage tables  implemented as a codon usage search engine • Software designated for compatibility with Android and iOS • Development of strategy for international, open distribution of structure prediction tool
Codon Usage Powered Guided Protein Alignment via Hidden Markov Models (HMMs) and Dynamic Programming
Product Development
Paint Mixing Device
Accomplishments

• Designed, Built, and Tested a fully-functional autonomous robot to all required specifications in 1-month  • Advanced to 3rd round of competition • Perf boarded IR-sensing module  • No mechanical nor electrical issues lasting more than 12-hours • Only team to implement servo powered ball launching • Daily maintenance  of  webpage • Successful implementation of 4- level deep finite state machine in C  • Successful project management using scrum  • over 50 (20 of them fabricated using laser printer ) new parts and assemblies designed in SolidWorks • Version control and documentation through Dropbox and github.

Video of Droid passing minimum-specification:
https://drive.google.com/a/ucsc.edu/file/d/0B5AhAGdAOehONEdYVTBDVFlvUWs/view?usp=sharing

Project overview and requirements:
https://classes.soe.ucsc.edu/cmpe118/Fall15/Labs/ProjectOverview_SlugWars.pdf
CE-118- Mechatronics "Slug Wars: The Slime Awakens" Droid Competetion.
https://goo.gl/DVsK3p
Project: Design and Build Prototype for microfluidic device for mixing spider silk dope/other fiber substances in order to extrude thin fibers .

Work done: design, fabricate and test microfluidic device to extrude polymeric substances (i.e spider silk, silkworm silk, cellulose acetate fibers) into a fiber of diameter ~50-100um. Conduct research and obtain supporting material from scientific literature. Prepare list and bill of materials for project. Report/present any updates to professor/supervisor, obtain lab space and equipment, develop operating procedure for device, assess impact of device.
Design, Fabrication, and Testing of Microfluidic Spider Silk Extruder
Microbial fuel cells (MFCs) generate electricity via the anaerobic metabolism of certain types of bacteria. Such electrogenic organisms are able to transfer electrons during the metabolism of organic material. With a little bit of design, these bacteria can be used to generate an electric potential in a fuel cell. There is definite possibility that MFCs could be used extensively as a means to collect energy from waste water. Therefore, we have set out to create our own MFC, in a project where life and electronics aggregate together. 

The project's goal was to alter the metabolism of  through gene knock-ins and gene-knockouts Shewanella oniedensis, a known electrogenic bacteria, to both grown thicker biofilms and increase columbic efficiency of the organisms.A thicker biofim allows for greater surface are in contact with the catthode and ultimately higher rate of electron transfer. Increasing the columbic efficiency ensures that the bacteria utilizes its metabolites in a more efficient manner to produce more electrons to be transferred to the cathode. 

Accomplishments

•  Successfully Lead, Organized, and founded Team• Project approved and sponsored by faculty in UCSC Department of Chemistry • Crowd funding, including team video, campaign for materials, registration, and travel cost • Attended, organized UCSC hosted Northern California iGEM meetup • Managed Lab space and materials • Performed experiments and scheduled experiments for team • Well received project presentation (poster and talk) at Giant Jamboree in Boston, MA. • First team to represent UCSC at the jamboree on a world stage • consulted with teams internationally • wiki page created/maintained containing project information and updates • submission of project results to iGEM headquarters in Boston, MA
Increasing Power Output of Microbial Fuel Cells via Metabolic Modification of Shewnella Oidensis
http://2014.igem.org/Team:UC-Santa_Cruz-BioE
Mass production of high-quality, high-strength spider silk fibers has proven itself to be allusive in an industrial setting many times over due to spider silk proteins' complex and precise purification process. In this study we chose Caulobacter Crescentus (CB15) , a gram negative most widely studied for its asymmetric division, to produce a major ampullate spidroin (MaSps) silk protein fragment. CB15 was chosen for its ability to secrete, through a type-1 secretion system,  high amounts a loosely connected membrane protein, RsaA that can be precipitated into the culture medium upon shaking. By creating a fusion protein with our MASP fragment and RsaA, along with a thrombin restriction site between them, we hoped to create a simple spider silk production process with minimal required purification. From this study, we learned that successful secretion in CB15 is heavily dependent on the size of the protein and thus adding a fusing RsaA with our MaSp fragment, or even a smaller YFP protein, creates too large for successful type-1 secretion.

Accomplishments

• Modified an expression plasmid for: extracellular recombinant spider-silk fusion protein expression, thrombin cleavage of fusion protein, promoter for fusion protein, and restriction enzyme sites • completed proof of concept fluorescent fusion protein plasmid • completed design of protocol for expression and purification • Results presented to faculty and peers • Project managed with GANNT chart and google drive
Design and Testing of DNA constructs for high yield expression of recombinant spider silk in Caulobacter Crescentus(CB15).
https://goo.gl/05cdkO
" Fresh water shortages affect half of the world’s population (currently 7 billion persons). In the next 25 years the numbers of people impacted by severe water shortages is expected to increase four fold. Shortage of potable water has been estimated to account for 80-90% of disease and 30% of mortality for humanity. Roughly half of all accessible fresh waters (rivers, lakes and underground aquifers) are estimated to be in use by the current world population. Given only 2.5 percent of the total volume of water is fresh water and this percentage is shrinking with global warming, fresh water is becoming a critical limiting resource for human populations. The goal of this project is to develop an efficient, green, scalable, low cost solution for desalinization of sea water and brackish water. Our solution is creation of a biofilm (biomachine) which uses sunlight to pump sodium chloride across the biofilm for the desalinization of salt and brackish waters, essentially replacing the pump, membrane, and energy source of a reverse osmosis machine. The project also provides a scaffold for possible biofilm cleanup of heavy metals and other toxic ionic pollutants."

Accomplishments

• Project approved and obtained funding by UCSC Department of Biomolecular Engineering • Obtained expression plasmids from Stanford University • Successful fluorescent, polarized biofilm production identified using confocal microscope  • Successful isolation of coding sequences from two ion transport proteins from their respective organisms • Identification of multiple proteins responsible for polarization and spatial organelle coordination • wiki page created/maintained containing project information and updates • submission of project results to iGEM headquarters in Boston, MA. • First iGEM competition entry for UCSC
Water desalination in Caulobacter Crecentus via biomolecular Light and Voltage Gated Ion Pumps and Channels.
http://2013.igem.org/Team:UC-Santa_Cruz/Team
UC Santa Cruz
https://www.linkedin.com/company/ucsc
UCSC's 1st Annual Campus Clean-up!

Excellent opportunity to clean-up our beautiful campus as well as meet new people and gain new perspectives.

For more info:
http://sustainability.ucsc.edu/get-involved/student-projects/zerowaste/Campus%20Cleanup%20Day/index.html
https://media-exp1.licdn.com/dms/image/C560BAQFsjvxBDYgQMA/company-logo_100_100/0/1565726655033?e=1655942400&v=beta&t=nXYi4hYyLXLohP0VBXG5NnI4QxWaww9NkbeK6pV-0ns
Waste Removal
Science and Technology
UCSF
https://www.linkedin.com/company/ucsf
Cognitive/Behavioral experiments with EEG and MRI for Neuroscience Study with Gazzaley Lab at USCF Sandler Neuroscience Center.

For more info:
http://gazzaleylab.ucsf.edu/
https://media-exp1.licdn.com/dms/image/C4E0BAQEQLo6jPY08UA/company-logo_100_100/0/1519856120396?e=1655942400&v=beta&t=YiBLeAobJccoJTVpUmKreIbua-z5_Dji498b4lM-O70
Research Subject
Health
Children's Tumor Foundation
https://www.linkedin.com/company/children%27s-tumor-foundation
Hackathon to end NEUROFIBROMATOSIS at Google Launchpad in San Francisco, CA


Project:
Machine Learning techniques and exploratory data analysis for a multi-faceted approach to drug efficacy assessment. Git repo: https://github.com/SVAI/teamone


“The Children’s Tumor Foundation (CTF), the Neurofibromatosis Therapeutic Acceleration Program (NTAP), Sage Bionetworks, and SVAI are excited to announce the second Neurofibromatosis (NF) hackathon that will be held at the Google Launchpad at 543 Howard Street in San Francisco on September 13-15, 2019. This event is in concomitance with the 2019 CTF Patient Forum and NF Conference that will kickoff on September 20 until the 24. The 2019 Hackathon will focus on analyzing diverse datasets including genomic, drug screening, drug-target association, imaging, and other data for all the three conditions of NF (NF1, NF2, Schwannomatosis)”


Event page:
https://sv.ai/neurofibromatosis
https://media-exp1.licdn.com/dms/image/C4D0BAQFyCKaMBmBaGw/company-logo_100_100/0/1519856475300?e=1655942400&v=beta&t=c99huZd8j9AMV3n_Pn1hor0xaG-aA0-uIvkc-NaaFjQ
Hacker
Health
Children's Tumor Foundation
https://www.linkedin.com/company/children%27s-tumor-foundation
Hack for NF (Neurofibromatosis): a global, virtual hackathon to advance research, clinical innovation, and quality of life for NF patients.


Project Pharmacomb:

Collaboration with Professor of Pharmacology Jeffrey Field of Perelman School of Medicine University of Pennsylvania 

A Web-based data visualization tool that provides a database of chemical screens against NF1 and NF2. This tool will support NF1 and NF2 researchers in speeding up the drug discovery efforts.


https://nfhack-platform.bemyapp.com/#/projects/5faeeb187b6579001bf9d85c

Github:

https://github.com/pmacswebteam/drug-data
https://media-exp1.licdn.com/dms/image/C4D0BAQFyCKaMBmBaGw/company-logo_100_100/0/1519856475300?e=1655942400&v=beta&t=c99huZd8j9AMV3n_Pn1hor0xaG-aA0-uIvkc-NaaFjQ
Web Developer
University of Michigan
www.coursera.org
Z43PNJLCU4NL
Using Python to Access Web Data
https://www.coursera.org/account/accomplishments/certificate/Z43PNJLCU4NL
Duke University
www.coursera.org
F8SS3SDUTECY
Programming Foundations with JavaScript, HTML and CSS
https://www.coursera.org/account/accomplishments/certificate/F8SS3SDUTECY
IBM
www.coursera.org
REPRAZCA6BYW
Databases and SQL for Data Science
https://www.coursera.org/account/accomplishments/certificate/REPRAZCA6BYW
University of Michigan
www.coursera.org
KL7XSHF6VBWQ
Python Data Structures
https://www.coursera.org/account/accomplishments/verify/KL7XSHF6VBWQ
Fire Extinguisher Training.com
fireextinguishertraining.com
Fire Extinguisher Training
http://fireextinguishertraining.com
Environmental Health & Saftey, University of California, Santa Cruz
Laser Cutter Training
Environmental Health & Saftey, University of California, Santa Cruz
Laboratory Biosafety and Bloodborne Pathogen Training
Environmental Health & Saftey, University of California, Santa Cruz
Hazardous Waste Management for Laboratory Personnel
Environmental Health & Saftey, University of California, Santa Cruz
Introduction to Laboratory Safety
Environmental Health & Saftey, University of California, Santa Cruz
UC Laboratory Safety Fundamentals
https://in.linkedin.com/in/helix-data-informatics-970486140
Pune/Pimpri-Chinchwad Area
Helix Data Informatics
CRO , Training, Placement in Bioinformatics at Helix Data Informatics
https://www.linkedin.com/in/johnvu86
San Jose, CA
John Le
Business Development Manager
https://www.linkedin.com/in/daniela-bolanos-481507a7
Santa Cruz, CA
Daniela Bolanos
--
https://www.linkedin.com/in/francis-albert-apolinario-286b19132
Chicago, IL
Francis Albert Apolinario
--
https://www.linkedin.com/in/eugenele
Sunnyvale, CA
Eugene Le
Student
https://www.linkedin.com/in/adrianalanderos
Greater Chicago Area
Adriana Landeros
PhD Student at Northwestern University Feinberg School of Medicine
https://www.linkedin.com/in/joannabperez
Clarkston, GA
Joanna Perez
Lab Scientist l Research Assistant I Seeking new role
https://www.linkedin.com/in/jovany-cruz-60a44b61
King City, CA
jovany cruz
Technology and Innovation Manager at Scheid Family Wines
https://www.linkedin.com/in/grant-palmer-458372133
Brooklyn, NY
Grant Palmer
Brooklyn, NY
https://www.linkedin.com/in/samanthasal1
Los Angeles Metropolitan Area
Samantha Salazar
Interventionist at Little Lake City School District
https://www.linkedin.com/in/khanh-nguyen-075012106
Salinas, CA
Khanh Nguyen
Water Conservation Specialist
https://www.linkedin.com/in/jean-le-6666b79
Santa Clara, CA
Jean Le
Principal Member of Technical Staff at Maxim Integrated
https://www.linkedin.com/in/ali-muckadam-msc-7aa2652
San Francisco Bay Area
Ali Muckadam (MSc)
Design, Verification & Validation
https://www.linkedin.com/in/eugene-alejo
San Francisco, CA
Eugene Alejo
An aspiring customer service representative / counselor who is addressing the concerns and needs of various clients.
https://www.linkedin.com/in/amandaspence12
Sunnyvale, CA
Amanda Spence
Current Graduate Student working towards a Masters and a Single Subject Teaching Credential in Math
https://www.linkedin.com/in/vincent-sun-2610648a
San Jose, CA
Vincent Sun
--
https://www.linkedin.com/in/carolvan58795
San Jose, CA
Carol Van
Safety Compliance Manager ( Regulatory Compliance ) at Supermicro
https://www.linkedin.com/in/pavlo-vlastos
Santa Cruz, CA
Pavlo Vlastos
Graduate Researcher
Louis Clark
      
          



            
              
        
              
  

    
        Aaron brought a special combination of coding abilities and instrument communications level understanding to a key position at MBP Titan/Intrexon.  He became the group expert on the Ignition software, handled many data availability problems, and built an API to unify our access.  His main responsibility was integration of a diverse set of microfermentation instruments into our existing continuous fermentation data processing system.  The responsibility was carried out with a large degree of independence and positive feedback from his customers on the lab side.  I found Aaron to be a team asset whose work was exceptionally reliable.
https://uk.linkedin.com/in/aaron-m-23b929173
Manchester Area, United Kingdom
Aaron M.
Contract Recruitment Specialist
https://www.linkedin.com/in/aaron-m-b81b407a
New York City Metropolitan Area
Aaron M
Managing Member at ASM International
https://www.linkedin.com/in/aaron-m-420b01148
Fayetteville, NC
Aaron M
Retiring 2022
https://uk.linkedin.com/in/aaron-mcelhinney
Cumbernauld
Aaron M.
Consulting Engineer at Ping Network Solutions
https://ph.linkedin.com/in/aaronmarasigan
Las Piñas
Aaron M.
Video Editor / Videographer
Current and Former Slug 118'ers
https://media-exp1.licdn.com/dms/image/C4D07AQECjgMG-YQdaw/group-logo_image-shrink_200x200/0/1631365769946?e=1647694800&v=beta&t=XuSfxav3PpwlYcXWtyjqO_K4FM8Oit8DBE8M7GGDfCs
https://www.linkedin.com/groups/4425651
BIOMEDICAL ENGINEERING
https://media-exp1.licdn.com/dms/image/C5607AQEe6s0ggHDaVg/group-logo_image-shrink_92x92/0/1521152554495?e=1647694800&v=beta&t=jkDEDsYKwzw8OrMPTW7vdIAvvEDxlDZ9uSrY5-oHF50
https://www.linkedin.com/groups/1787393
Former MBP Titan Employees
https://static-exp1.licdn.com/sc/h/4h1ldzvvebtszyx75ve7dst1v
https://www.linkedin.com/groups/8927003