arif rahman , ph.d .
Clinical Research Scientist I at Impact Pharmaceutical Services
clinical research scientist || medical writer || pharmacologist & toxicologist
Impact Pharmaceutical Services
https://www.linkedin.com/company/impact-pharmaceutical-services
Duties/responsibilities:
* Author clinical, scientific, and regulatory submission documents such as study protocols, clinical study reports, subject narratives, clinical investigator brochures, and other documents as assigned.
* Perform quality control review of regulatory submission documents.
Raleigh-Durham-Chapel Hill Area
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Clinical Research Scientist I
Impact Pharmaceutical Services
https://www.linkedin.com/company/impact-pharmaceutical-services
Duties/responsibilities:
* Author clinical, scientific, and regulatory submission documents such as clinical study reports, subject narratives, and other documents as assigned.
* Perform quality control review of regulatory submission documents.
Raleigh-Durham-Chapel Hill Area
https://media-exp1.licdn.com/dms/image/C4D0BAQGCMWGhU7HSxg/company-logo_100_100/0/1519885956434?e=1655942400&v=beta&t=2LZsLv1C3xzNFrhJ-uwHT5_Xq8slh9i-hfmd598ugqc
Medical Writing Fellow
PLOS One
Reviewer
Nature Research (Publishing)
https://www.linkedin.com/company/natureportfolio.
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Reviewer
Environmental Factor
▪ Wrote and edited non-technical stories on the latest scientific discoveries across the NIEHS
▪ Wrote and edited feature stories on special events such as conferences and distinguished lecture series.
▪ Interviewed scientists to highlight the ‘big picture’ aspect of their research for general public.

Sample writing pieces-
▪ https://factor.niehs.nih.gov/2021/1/science-highlights/trainor/index.htm
▪ https://factor.niehs.nih.gov/2020/12/science-highlights/aging-cancer-interplay/index.htm
▪ https://factor.niehs.nih.gov/2020/10/science-highlights/xchromosome-inactivation/index.htm
▪ https://factor.niehs.nih.gov/2020/7/community-impact/reduce-exposure/index.htm
▪ https://factor.niehs.nih.gov/2020/8/papers/dir/index.htm#a1
▪ https://factor.niehs.nih.gov/2020/6/papers/dir/index.htm#a4
▪ https://factor.niehs.nih.gov/2020/5/papers/dir/index.htm#a4
Science Writer
National Institute of Environmental Health Sciences (NIEHS)
https://www.linkedin.com/company/national-institute-of-environmental-health-sciences-niehs-
Used gene coexpression-based network analysis to investigate chemical-induced cardiovascular toxicity.
Data type and tools:
- High-throughput gene expression (e.g. microarray) data
- R & R Shiny
- Partek Genomics Suite
- MySQL/PostgresSQL
- Tableau
- Cytoscape
- JMP
- Ingenuity Pathway Analysis (IPA)



Supervisors: Dr. Scott Auerbach and Dr. Brian Berridge.
Raleigh-Durham, North Carolina Area
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Postdoctoral Fellow
The University of Tennessee Health Science Center
https://www.linkedin.com/company/university-of-tennessee-health-science-center
Research Experience:
* Designed in vitro and ex vivo toxicological/mechanistic study involving CYP enzymes
* Conducted pharmacodynamic and toxicological analysis of novel CYP2E1 inhibitors (lead optimization)
* Studied drug- drug/disease interaction (DDI) involving alcohol-HIV-anti-retroviral drugs
* Conducted in vitro pharmacokinetic analysis of anti-retroviral drugs using LC-MS/MS
* Executed enzyme activity assay using liver microsomes/baculosomes
* Performed screening of enzyme substrate/inhibitor, kinetics study (e.g. Km, Vmax, IC50 determination)
* Studied exosomes biology; isolation, characterization, and downstream effects on cell systems 
* Used exosomes as potential biological carrier for large molecules such CYP enzymes 
* Extensive experience in working in biosafety level (BSL)- 2 & 3 facility
* Gained theoretical knowledge and understanding of Pop PK, PBPK modeling, WinNonlin, NONMEM
* Participated in hands on training and exercises on PKPD of protein therapeutics (Dr. Bernd Meibohm)

Technical skills:
•	Enzyme activity/inhibition assay
•	Metabolic assay using human liver microsomes
•	Molecular docking
•	Flow cytometry
•	Cell viability/cytotoxicity assay
•	ELISA
•	LCMS/MS method development and validation
•	Western blot
•	qRT-PCR
•	DNA/RNA/protein extraction/quantification
•	DNA damage assay
•	Cytokine assay
•	Immunohistochemical assay using fluorescence microscopy
•	Antioxidant activity assay
•	Glutathione assay
•	Lipid peroxidation assay
•	Exosomes isolation/characterization assay
•	Membrane protein extraction assay
•	Nanoparticle uptake assay 

Software skills:
R, GraphPad Prism, SAS, Microsoft Excel

Cell culture experience:
•	Hepatocytes (primary & immortalized)
•	Monocytes & Macrophages 
•	Monocyte-derived microglia
•	HIV infected monocytes (U1 cells)
•	Astrocytes (human & mouse)
•	Neuroblastoma cell
•	Endothelial cells (in vitro BBB model)
•	Human plasma (healthy & patient sample)

https://scholar.google.com/citations?user=l3DM3ysAAAAJ&hl=en
Greater Memphis Area
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Graduate Research Assistant
The University of Tennessee Health Science Center
https://www.linkedin.com/company/university-of-tennessee-health-science-center
As a Teaching Assistant of Pharmacokinetics and Dose Optimization, I helped P2 students with their recitations and grading the exams, quizzes, and assignments.
My responsibility in the compounding lab was to teach the Pharm D students aseptic techniques of administering parenteral compounds.
As a Teaching Assistant of Pharmaceutics, I took care of the grading & uploading the grades in the blackboard as well as updating the students regarding their progress in the course during the semester.
Greater Memphis Area
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Graduate Teaching Assistant
FDA
https://www.linkedin.com/company/fda
* Learnt predictive model development for drug-induced liver injury (DILI)
* Used R, KNN, 5-fold cross validation along with other data mining approaches to build the models
* Learnt data preprocessing, feature scaling, regression modeling, etc. using R
* Gained knowledge on DILIrank, the largest reference DILI drug list developed by FDA
* Studied liver toxicity knowledge base and DILI classification for assessment of human liver injury
Pine Bluff, Arkansas Area
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ORISE Fellow
Incepta Pharmaceuticals Ltd.
https://www.linkedin.com/company/incepta-pharmaceuticals-ltd-
Roles and achievement:
•	Supervised two new team members in their transition into the workplace and helped them planning the marketing strategies for their assigned products.
•	Managed marketing and distribution of 2 major revenue earning products of the company successfully.
•	Prepared annual reports for my team using Microsoft Excel and PowerPoint.
Tejgaon, Dhaka
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Senior Product Manager
Incepta Pharmaceuticals Ltd.
https://www.linkedin.com/company/incepta-pharmaceuticals-ltd-
Roles and achievement:
•	Implemented novel marketing strategies for amino acid preparation and made it the 2nd largest brand nationally (from 6th position) in terms of annual sales value.
•	Re-launched the iron preparation with change in packaging which added around 7.5 million BDT extra to the company’s total monthly revenue.
•	Introduced two new generic medicines into market which added around 5 million BDT to the company’s monthly revenue.
•	Anchored the company’s biggest year-end celebration ‘Annual Conference (2012)’.
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Product Manager
Essentials Drug Company Limited, Bangladesh
I had an unique opportunity to work as an intern in the  country's  only state owned Pharmaceutical Company, Essential Drugs Company Limited. It's main objective is to manufacture quality drugs at an affordable price & supply to the Government Hospital and other Health Institutions. The company is the major  supplier of  Essential Drugs to the Government Hospitals, Civil Surgeon’s Offices, Health Institutions of Government, Non-Government and International (Non-profit makings) Organizations like UNICEF, WHO etc.

During my internship, I had hands on training on multiple aspects of drug manufacturing such as  R&D, QA/QC, regulatory approval, and marketing and distribution. The experience that I gathered here helped me tremendously to find the proper direction in my career in pharmaceutical industry.
Dhaka, Bangladesh
Intern
Doctor of Philosophy - PhD
Dissertation: "Identification of novel CYP2E1 inhibitor to investigate cellular and exosomal
CYP2E1-mediated toxicity"
Pharmacology and Toxicology
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The University of Tennessee Health Science Center
https://www.linkedin.com/school/university-of-tennessee-health-science-center/
Master of Science - MS
Thesis: "Pharmacokinetic effect of drug-drug interaction between Clopidogrel and Omeprazole in healthy human volunteer"
Clinical Pharmacy and Pharmacology
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University of Dhaka
https://www.linkedin.com/school/dhakauniversity/
Bachelor of Pharmacy (B.Pharm.)
Pharmacy
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University of Dhaka
https://www.linkedin.com/school/dhakauniversity/
American Chemical Society (ACS)
Graduate Student Membership
Student Academic Alliance chapter at LifeScienceTennessee
Member
Society on Neuroimmune Pharmacology (SNIP)
Graduate student member
American Association of Pharmaceutical Scientists (AAPS)
Student Member
Novel elvitegravir nanoformulation for drug delivery across the blood-brain barrier to achieve HIV-1 suppression in the CNS macrophages
Nature Scientific Reports
https://www.nature.com/articles/s41598-020-60684-1
https://doi.org/10.1201/9780429295034
Cytochrome P450 Enzymes for the Synthesis of Novel and Known Drugs and Drug Metabolites
Pharmaceutical Biocatalysis by Jenny Stanford Publishing
https://www.crcpress.com/Pharmaceutical-Biocatalysis-Fundamentals-Enzyme-Inhibitors-and-Enzymes/Grunwald/p/book/9789814800617
Plasma exosomes exacerbate alcohol- and acetaminophen-induced toxicity via CYP2E1 pathway
Nature Scientific Reports
https://doi.org/10.1038/s41598-019-43064-2
Extracellular Vesicles: Intercellular Mediators in Alcohol-Induced Pathologies
Journal of Neuroimmune Pharmacology
https://link.springer.com/article/10.1007%2Fs11481-019-09848-z
In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV replication
Toxicology Letters
https://doi.org/10.1016/j.toxlet.2018.04.023
Novel elvitegravir nanoformulation approach to suppress the viral load in HIV-infected macrophages
Biochemistry and Biophysics Reports
http://www.sciencedirect.com/science/article/pii/S2405580817302145
Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors
Pharmacology Research & Perspectives
http://onlinelibrary.wiley.com/doi/10.1002/prp2.362/full
Specific packaging and circulation of cytochromes P450, especially 2E1 isozyme, in human plasma exosomes and their implications in cellular communications
Biochemical and Biophysical Research Communications
http://www.sciencedirect.com/science/article/pii/S0006291X17315036
Effect of Polyaryl Hydrocarbons on Cytotoxicity in Monocytic Cells: Potential Role of Cytochromes P450 and Oxidative Stress Pathways
PLOS ONE
http://dx.doi.org/10.1371/journal.pone.0163827
Effect of Ethanol on the Metabolic Characteristics of HIV-1 Integrase Inhibitor Elvitegravir and Elvitegravir/Cobicistat with CYP3A: An Analysis Using a Newly Developed LC-MS/MS Method
PLOS ONE
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149225
Advanced SAS
-
Bio-statistics for health science I
-
Bio-statistics for health science II
-
Drug Metabolism
-
Drug stability and chemical kinetics
-
Entrepreneurship in Pharmaceutical and Biomedical Sciences
-
Essentials of Animal Experimentation
-
Fundamentals of SAS for epidemiology
-
Integrity in the conduct of Scientific Research
-
Introduction to R Part I
-
Introduction to R Part II
-
Pharmaceutical Analysis
-
Pharmaceutical Preformulation and Drug Product Development
-
Pharmacokinetics and Dose optimization
-
Pharmacokinetics, Pharmacodynamics and Drug Development (Advanced Pharmacokinetics)
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Population Pharmacokinetics
-
Education
AAPS student chapter
* Represented the Student Chapter for UTHSC at AAPS meetings
* Directed the Student Chapter and presided at its different meetings
* Appointed committee members and committee Chairs as necessary.
Chair
Education
AAPS Student Chapter
Assisted the Chair or sometimes acted as Chair in the absence of the Chair or as necessary in organizing journal club seminars and other workshops associated with American Association of Pharmaceutical Scientists student chapter.
Chair-elect
Education
Graduate Student Executive Committee (GSEC) at UTHSC
To be a part of the GSEC allowed me to be involved in the services of my fellow colleagues at UTHSC in several aspects such as helping in creating platforms for students to show their work in the broader scientific community, resolving issues which are currently hampering smooth progress in the school etc.
Secretary
Social Services
International Students Association at UTHSC
Helped new international students to smoothly start their journey at UTHSC by helping to overcome the culture shock and provide with advice that may guide them to a better graduate life.
President
Social Services
International Students Association at UTHSC
Secretary
Health
IPECS Advisory Committee (UTHSC Inter-professional Student Council)
The IPECS advisory committee acts as a liaison between the student body and the Office of Inter-professional Education and Clinical Simulation. Activities included-

- Served as student representatives on IPECS committees
- Provided student feedback on college curriculums and suggested ways to integrate IPE
- Informed IPECS about IPSC activities
Committee member
Toastmasters International
https://www.linkedin.com/company/toastmasters-international
To improve my communication and leadership skill I joined Toastmasters international. In the process, I get to help other members to improve their communication and leadership skill.
https://media-exp1.licdn.com/dms/image/C4D0BAQEPWFTxzFWmPA/company-logo_100_100/0/1631737885617?e=1655942400&v=beta&t=H0uK_-2sN6pjshxDujcYDyps2qgK6kK2tQjWJAykmZY
Member
LinkedIn
www.linkedin.com
Grammar Foundations
http://www.linkedin.com/learning/grammar-foundations
LinkedIn
www.linkedin.com
Digital Transformation
http://www.linkedin.com/learning/digital-transformation-2
LinkedIn
www.linkedin.com
Writing in Plain English
http://www.linkedin.com/learning/writing-in-plain-english
Stanford University
coursera.org
coursera.org/verify/X6CE2K3Y849P
Writing in the Sciences
https://coursera.org/share/76d9383485f7fd912c621c0195a2a3f3
Imperial College London
coursera.org
Introduction to Statistics & Data Analysis in Public Health
https://coursera.org/share/36c2ae4a2ca5f9df1769217596580562
Harvard Global Health Institute
courses.edx.org
Improving Global Health: Focusing on Quality and Safety
https://courses.edx.org/certificates/239429748a074df2899c34c58816dfec
Coursera
www.coursera.org
Network Analysis in Systems Biology
https://www.coursera.org/account/accomplishments/certificate/MYCGQSPQRFVP
Duke University School of Medicine
Certification of Attendance by ORAQ Regulatory Affairs Training Program at Duke University
DataCamp
www.datacamp.com
#10672661
Data Manipulation with dplyr in R
https://www.datacamp.com/statement-of-accomplishment/course/a6e2a84554f4771474e65ddcb5d5f599ce593358
DataCamp
www.datacamp.com
#9547166
Importing Data in R (Part 1)
https://www.datacamp.com/statement-of-accomplishment/course/8e1f0e1668d0ff1d056ae6659d99684c793bbbfe
DataCamp
www.datacamp.com
#9918917
Cluster Analysis
https://www.datacamp.com/statement-of-accomplishment/course/5d2cc13a9b17115ff1b413da55b41fa45460d3de
DataCamp
www.datacamp.com
#9727767
Modeling with Data in the Tidyverse
https://www.datacamp.com/statement-of-accomplishment/course/c6e7247a25c88a4fed0f4ae7ceff9bd9f01f51a3
DataCamp
www.datacamp.com
9293922
Data Visualization with ggplot2 (Part 2)
https://www.datacamp.com/statement-of-accomplishment/course/18a5053c429556254e3dbf53ae9482c8838680c9
DataCamp
www.datacamp.com
#9546382
Exploratory Data Analysis in R: Case Study
https://www.datacamp.com/statement-of-accomplishment/course/b20d4742310619745b3a89bf8925e9a616fb9b61
DataCamp
www.datacamp.com
6506713
Data Visualization with ggplot2 (Part 1)
https://www.datacamp.com/statement-of-accomplishment/course/7da676ed854e41ec32114bbfa3a0a0f8f2408fff
DataCamp
www.datacamp.com
1
Introduction to the Tidyverse
https://www.datacamp.com/statement-of-accomplishment/course/8ab28248921511d31b2387df0c2e2b4c81fda063
Udemy
ude.my
UC-KJC7CRAO
Introduction to Finance, Accounting, Modeling and Valuation
http://ude.my/UC-KJC7CRAO
Udemy
ude.my
UC-0SCKR91V
Machine Learning A-Z:  Hands-on Python and R
http://ude.my/UC-0SCKR91V
LinkedIn
www.linkedin.com
AfQB1JIvOvzSQ516zTg-mC4Jfw6p
Data Wrangling in R
http://www.linkedin.com/learning/data-wrangling-in-r
University of California San Diego on Coursera
www.coursera.org
3DHCK9YALAK7
Drug Development
https://www.coursera.org/account/accomplishments/verify/3DHCK9YALAK7
DataCamp
www.datacamp.com
6,395,700
Intermediate R Course
https://www.datacamp.com/statement-of-accomplishment/course/8c5e0cb16ba203533f58c6730b89fe76103a39b5
DataCamp
www.datacamp.com
2,090,571
Introduction to R Course
https://www.datacamp.com/statement-of-accomplishment/course/1f71db4ca4b1fa0fa9a8ad854848561999d65ecc
Johns Hopkins Bloomberg School of Public Health
www.coursera.org
YFTPUH723TZY
R Programming
https://www.coursera.org/account/accomplishments/verify/YFTPUH723TZY
Johns Hopkins Bloomberg School of Public Health
www.coursera.org
5YQUR52LB9RT
The Data Scientist’s Toolbox
https://www.coursera.org/account/accomplishments/certificate/5YQUR52LB9RT
Plough Center for Sterile Drug Delivery Systems
The Comprehensive Industrial Course in the Preparation of Parenteral Products
College of Pharmacy, University of Tennessee Health Science Center
app.box.com
Certificate on Pharmacokinetics and pharmacodynamics of protein therapeutics: Concept and Hands on exercises
https://app.box.com/s/81tujdzeziyg4plug7erjy5vn61lkl34
https://www.linkedin.com/in/kasturipuranam
Durham, NC
Kasturi Puranam, Ph.D.
Clinical Research Scientist/Medical Writer
https://www.linkedin.com/in/alicia-carreiro-454a5768
Raleigh, NC
Alicia Carreiro
Clinical Research Scientist I at Impact Pharmaceutical Services
https://www.linkedin.com/in/dominic-luciano-58658578
Durham, NC
Dominic Luciano
Clinical Research Scientist at Impact Pharmaceutical Services
https://www.linkedin.com/in/ryanovercash1983
Raleigh, NC
Ryan Overcash
Owner and independent consultant at Clinsolutions, LLC
https://in.linkedin.com/in/rutuja-lad-383627138
Mumbai
Rutuja Lad
Jr. Research Associate Scientist at Macleods Pharma, R&D Mumbai
https://www.linkedin.com/in/l-alexis-hoeferlin-684a8525
Richmond, VA
L. Alexis Hoeferlin
Clinical Research Scientist II at Impact Pharmaceutical Services
https://www.linkedin.com/in/amritha-kidiyoor-ms-phd-96881a13
Raleigh-Durham-Chapel Hill Area
AMRITHA KIDIYOOR, MS, PhD
Senior Clinical Research Scientist at Impact Pharmaceutical Services
https://www.linkedin.com/in/stephanie-mixson-byrd-ph-d-rac-022bb925
United States
Stephanie Mixson Byrd, Ph.D., RAC
Senior Clinical Research Scientist at Impact Pharmaceutical Services
https://ca.linkedin.com/in/zahid-sadek-chowdhury
Vancouver, BC
Zahid Sadek Chowdhury, Ph.D.
Cybersecurity Specialist Trainee | Research Scientist | Pharmaceutical industry | Let's connect!
https://www.linkedin.com/in/caroline-drucker-98ab568
Durham, NC
Caroline Drucker
Medical Writer
https://www.linkedin.com/in/l-e-beth-wiener-drph-33079a93
Durham, NC
L.E. Beth Wiener, DrPH
Research Statistician at RTI International
https://www.linkedin.com/in/palak-patel-843969216
Merrimack, NH
Palak Patel
--
https://www.linkedin.com/in/bernicehuang
Germantown, TN
Bernice Wolen
Senior Medical Writer at Cardinal Health Regulatory Sciences
https://www.linkedin.com/in/danielle-garver-68a578138
Chapel Hill, NC
Danielle Garver
Student Intern at Impact Pharmaceutical Services
https://www.linkedin.com/in/christopher-del-corral-pharmd-18850877
Westwood, NJ
Christopher del Corral, PharmD
Director, Clinical Development and Sciences at Legend Biotech
https://in.linkedin.com/in/krisha-shah-633837121
Mumbai
Krisha Shah
Cancer Research Scientist
https://ca.linkedin.com/in/varunkatoch26
Toronto, ON
Varun K.
Masters In Regulatory Affairs at Northeastern University | Medical Devices | ICT Mumbai, 21 | Pharmaceutical Engineer
https://www.linkedin.com/in/kristen-moore-ph-d-24b75632
Durham, NC
Kristen Moore, Ph.D.
Epidemiology | Infectious Disease | Women's Health
https://www.linkedin.com/in/aschneibel
Knoxville, TN
Andrea Schneibel
Science Writer at Oak Ridge National Laboratory,
Fusion and Fission Energy and Science & US ITER
Narasimha Midde
      
          



            
              
        
              
  

    
        I have worked closely with Arif for more than two years. He is an excellent team player and a pleasant person to be around. The most striking thing about Arif is his ability to interact with people from diverse backgrounds and create an amicable atmosphere to move forward with any projects that he is involved in. I believe that Arif will be a great addition to any team either in the industry or academia. Ehsan Aziz
      
          



            
              
        
              
  

    
        Mr Arif Rahman is a very intelligent individual who takes keen interest in his work. 
His presence of mind and strong commitment to doing the right thing is much appreciated by his colleagues. 
His ability to go through issues at hand and develop clear concepts showed him to be an excellent candidate for future leadership. 
A significant portion of his work during his tenure at Incepta involved studying pharmacological aspect of different molecules so that he can identify and build on strategic advantages of each and promote these focal points. 
I believe he will be an asset to anyone who would like to involve him in their endeavor. 
https://www.linkedin.com/in/arif-rahman1538
Honolulu, HI
Arif Rahman, Ph. D.
Founder@ HIL>>Postdoctoral Fellow⇨Space Health⇨Energy Enthusiastic>>Micro/Nanorobotics» RF & Biotechnology developer ⇨Archer & Marathon runner