Ahmed Gomaa
Project Manager III at Red Hat
Project Manager III, CFO PMO
Experienced PMP with a background in Chemical Engineering and 8 years of experience in management consulting, project management, and strategic planning.
Red Hat
https://www.linkedin.com/company/red-hat
Raleigh-Durham-Chapel Hill Area
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Project Manager III
emendo inc.
https://www.linkedin.com/company/emendo-inc
Supported multinational pharmaceutical clients with the following tasks:
- Senior Project Manager of the fermentation plant qualification project ($1B facility) working with a team of two senior managers, 30+ engineers, and manufacturing associates, responsible for:
-- Developing and maintaining the project schedule, reporting tools, risk, and decision logs
-- Securing structured and systematic project execution 
-- Developing, and managing the escalation process with stakeholders
-- Driving issue resolution
-- Coordinating with cross-functional teams from other departments including automation and production support to provide the support needed for the project success
-- Reporting and presenting on project progress to the steering committee, and the global leadership

- Consultant for the PMO Office at a client facility:
-- Worked with a team of 10 documentation specialists to drive document handover from a major contractor clearing over a year of outstanding backlogs within weeks
-- Developed and executed a process for site-wide project prioritization working with SME’s and engineers from all units to collect, prioritize, and advocate projects ideas to upper management
-- Supported the development of departmental and site-wide annual goals through leading a series of workshops with department directors and the vice president of operations

- Consultant for the global operational excellence department for a multi-national pharmaceutical client:

-- Led a team of three consultants to develop a customized lean training program including over 30 modules (e.g. Kanban, 5S, and Kaizen) for a U.S.A. based production facility of 200 employees
Raleigh-Durham, North Carolina Area
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Project Leader
emendo inc.
https://www.linkedin.com/company/emendo-inc
Led shutdown projects for a pharmaceutical client facility ($1-2M projects), responsibilities included:
- Projects prioritization, scope development, and business case analysis
- Managing risk, decision, and escalation logs
- Monitoring project execution according to a strict timeline
- Schedule, scope, and budget control
- Reporting to the steering committee and maintaining communication site-wide

Led troubleshooting and improvement projects for a pharmaceutical client facility
- Employed technical experience and lean knowledge to run workshops with subject matter experts to address technical and R&D challenges
- Supported a series of improvement projects to the production process increasing yield by 30%
Raleigh-Durham, North Carolina Area
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Management Consultant
North Carolina State University
https://www.linkedin.com/company/north-carolina-state-university
Lead a team of graduate and graduate researchers to develop a delivery vehicle for CRISPR-Cas antimicrobials as a follow-up on PhD research.
North Carolina, United States
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Postdoctoral Researcher
North Carolina State University
https://www.linkedin.com/company/north-carolina-state-university
Beisel research group (https://beisel.wordpress.ncsu.edu/), Chemical and Biomolecular Engineering Department.

- Invented a platform technology for treating multidrug-resistant infections using the CRISPR-Cas3 system

- Demonstrated selective and titratable elimination of bacterial strains based on sequence information using CRISPR-Cas systems, featured in Nature, New York Times, Science News, Wired, and Faculty of 1000

- Published Four research articles with 900+ citations as of July 2021

- Led a team of graduate engineering and business students to develop a business case for the CRISPR-Cas3 antimicrobials leading to the foundation of Locus Biosciences

- Identified essential modules in the single guide RNAs (sgRNAs) responsible for Cas9 orthogonality

- Assisted in developing and teaching genome-engineering in mammalian and bacterial cells using CRISPR-Cas technologies, the first of its kind nationwide. Served as a teaching assistant for four chemical engineering courses

- Delivered talks at 3 national conferences

- Awarded 2 student scholarship awards to present at 2 national conferences

- Won 4 poster awards and 1 oral presentation award demonstrating excellent communication and presentation skills.

Experienced in Genome editing using CRISPR-Cas, Cas9 guide RNA design, recombination, bacterial and mammalian cell culture, cloning, PCR, gel electrophoresis, nucleic acid isolation, protein purification, flow cytometry, RT-PCR, site-directed mutagenesis, recombinant DNA techniques, bacteriophage engineering, plaque assays.
Raleigh-Durham, North Carolina Area
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Graduate Research and Teaching Assistant
Locus Biosciences
- Advised the board of directors on CRISPR antimicrobial research directions

- Invented the CRISPR antimicrobial platform and its drug delivery vehicle

- Performed market analysis, product value propositions and prepared the company’s business plan through  the Hi-TEC certificate program at POOLE’s college of management, North Carolina State University
Raleigh, North Carolina
Co-Founder and S.A.B. Advisor
Environics - Egypt
Part-time environmental analyst.
- Prepared Environmental Impact Assessments for new and running industrial plants.
- Prepared Life Cycle Analysis for new products.
Environmental Analyst
Teaching and research assistant
- Conducted a case study to apply Internal Heat Integration Columns Propane/Propylene Splitters.
- Taught Chemical Engineering classes and problem solving sessions including Petroleum Engineering, and Process Control.
Cairo University
Doctor of Philosophy (PhD)
Thesis title: "Programmable killing of bacterial strains using CRISPR-Cas systems”
Chemical and Biomolecular Engineering
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North Carolina State University
https://www.linkedin.com/school/north-carolina-state-university/
Graduate Technology Entrepreneurship and Commercialization Certificate Program (Hi-TEC)
The Graduate Certificate in Technology Entrepreneurship and Commercialization (TEC) at North Carolina State University is a unique interdisciplinary program that provides students the knowledge, skills and tools needed for bringing technology innovations to market. The curriculum is equally valuable for those seeking to start a new company based on an innovative technology and for those working within an established firm to bring new technologies to the marketplace.
https://tec.poole.ncsu.edu/graduate-programs/tec-certificate/
Entrepreneurship/Entrepreneurial Studies
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North Carolina State University Poole College of Management
https://www.linkedin.com/school/nc-state-university-poole-college-of-management/
Master's degree
Chemical and Biomolecular Engineering
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North Carolina State University
https://www.linkedin.com/school/north-carolina-state-university/
Master's degree
Thesis Title: “New developments on Internal Heat Integrated Distillation Column (i-HIDiC) - a Case Study on Propane/Propylene Splitter”
Chemical Engineering
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Cairo University
https://www.linkedin.com/school/cairo-university/
Bachelor of Science (BSc)
Graduated with honors in Chemical Engineering. Designed a modified bubble reactor in my graduation project. Co-founded OneHand Student Organization.
Chemical Engineering
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Cairo University
https://www.linkedin.com/school/cairo-university/
CRISPR-Cas adaptive immune systems in prokaryotes boast a diversity of protein families and mechanisms of action, where most systems rely on protospacer-adjacent motifs (PAMs) for DNA target recognition. Here, we developed an in vivo, positive, and tunable screen termed PAM-SCANR (PAM screen achieved by NOT-gate repression) to elucidate functional PAMs as well as an interactive visualization scheme termed the PAM wheel to convey individual PAM sequences and their activities. PAM-SCANR and the PAM wheel identified known functional PAMs while revealing complex sequence-activity landscapes for the Bacillus halodurans I-C (Cascade), Escherichia coli I-E (Cascade), Streptococcus thermophilus II-A CRISPR1 (Cas9), and Francisella novicida V-A (Cpf1) systems. The PAM wheel was also readily applicable to existing high-throughput screens and garnered insights into SpyCas9 and SauCas9 PAM diversity. These tools offer powerful means of elucidating and visualizing functional PAMs toward accelerating our ability to understand and exploit the multitude of CRISPR-Cas systems in nature.
Identifying and visualizing functional  PAM diversity across CRISPR-Cas systems
Mol Cell, 62(1):137-47 (2016)
http://www.cell.com/molecular-cell/pdf/S1097-2765(16)00175-1.pdf
Two recent publications have demonstrated how delivering CRISPR nucleases provides a promising solution to the growing problem of bacterial antibiotic resistance.
A CRISPR design for next-generation antimicrobials.
Genome Biology 15 (11), 516 (2014)
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-014-0516-x
Ahmed Gomaa, Alexandra Briner, and Paul Donohoue are co-first authors.
The RNA-guided Cas9 endonuclease specifically targets and cleaves DNA in a sequence-dependent manner and has been widely used for programmable genome editing. Cas9 activity is dependent on interactions with guide RNAs, and evolutionarily divergent Cas9 nucleases have been shown to work orthogonally. However, the molecular basis of selective Cas9:guide-RNA interactions is poorly understood. Here, we identify and characterize six conserved modules within native crRNA:tracrRNA duplexes and single guide RNAs (sgRNAs) that direct Cas9 endonuclease activity. We show the bulge and nexus are necessary for DNA cleavage and demonstrate that the nexus and hairpins are instrumental in defining orthogonality between systems. In contrast, the crRNA:tracrRNA complementary region can be modified or partially removed. Collectively, our results establish guide RNA features that drive DNA targeting by Cas9 and open new design and engineering avenues for CRISPR technologies.
Guide RNA functional modules direct Cas9 activity and orthogonality
Mol Cell, 56(2):333-9 (2014)
http://www.cell.com/molecular-cell/abstract/S1097-2765(14)00751-5
Controlling the composition of microbial populations is a critical aspect in medicine, biotechnology, and environmental cycles. While different antimicrobial strategies, such as antibiotics, antimicrobial peptides, and lytic bacteriophages, offer partial solutions, what remains elusive is a generalized and programmable strategy that can distinguish between even closely related microorganisms and that allows for fine control over the composition of a microbial population. This study demonstrates that RNA-directed immune systems in bacteria and archaea called CRISPR-Cas systems can provide such a strategy. These systems can be employed to selectively and quantitatively remove individual bacterial strains based purely on sequence information, creating opportunities in the treatment of multidrug-resistant infections, the control of industrial fermentations, and the study of microbial consortia.
Programmable removal of bacterial strains using genome-targeting CRISPR-Cas systems
mBio 5, e00928–13 (2014)
http://mbio.asm.org/content/5/1/e00928-13
Education
ESA: Egyptian Student Association
https://www.linkedin.com/company/esa-egyptian-student-association
Had the pleasure to lead the Egyptian Student Association - North Carolina State University Chapter for 3 years. Throughout this experience, we served a large number of incoming international students, helped them settle in the city and network. We also represented Egypt in a number of cultural events sponsored by the Office of International Services at NCSU.
Finally, we networked with a number of other organizations to organize social events to celebrate a number of our holidays with the community providing several chances for interactions and networking.
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President
Social Services
Alnoor Islamic Center
Chief Executive Officer
Project Management Institute
2642969
Project Management Professional (PMP)
North Carolina State University - POOLE College of Management
tec.poole.ncsu.edu
Graduate Technology Entrepreneurship and Commercialization Certificate Program (Hi-TEC)
https://tec.poole.ncsu.edu/graduate-programs/tec-certificate/
https://www.linkedin.com/in/tracy-wilshire-1073196
Durham, NC
Tracy Wilshire
Principal Business Analyst at Red Hat
https://www.linkedin.com/in/eric-rollins-a111527
Raleigh, NC
Eric Rollins
Manager, QA Critical Systems at APP Pharmaceuticals
https://ca.linkedin.com/in/siribaber
Toronto, ON
Siri Baber
Senior Incentive Analyst
https://www.linkedin.com/in/ingridbarton1
Raleigh, NC
Ingrid Barton
Operations Professional looking for new and exciting opportunities.
https://www.linkedin.com/in/mabdelh2
Raleigh-Durham-Chapel Hill Area
Mostafa Abdelhamid
PhD candidate at North Carolina State University
https://www.linkedin.com/in/jacqueline-bidlack-6b6246127
Raleigh, NC
Jacqueline Bidlack
Consultant at emendo inc.
https://www.linkedin.com/in/sam-ayoub-0728807
Raleigh, NC
Sam Ayoub
Principal at 962 Properties
https://www.linkedin.com/in/ali-talaat-548b9410b
Charlotte, NC
Ali Talaat
PM & superintendent
https://www.linkedin.com/in/mohamed-beshr-506a1371
Charlotte, NC
Mohamed Beshr
Senior Engineer, Virtual Technologies at Trane Technologies
https://www.linkedin.com/in/clayton-hubbard-b092415b
Cary, NC
Clayton Hubbard
Sr. Automation & Systems Engineer at Steady State Engineering
https://www.linkedin.com/in/david-erhart-0781788
Greensboro--Winston-Salem--High Point Area
David Erhart
Sr. Process Engineer at Aimmune Therapeutics
https://www.linkedin.com/in/dave-lev-07963572
Greater Chicago Area
Dave Lev
I’m retired mostly.   I mean if you have an interesting thought.  I’d listen....
https://www.linkedin.com/in/alan-jonhson-46552389
Raleigh, NC
Alan Jonhson
Technical Writer at Fresenius Kabi USA
https://www.linkedin.com/in/joshuazwarren
Boston, MA
Joshua Z. Warren, M.D.
Vice President, Private Equity at BPEA
https://www.linkedin.com/in/stuti-agrawal-93183246
San Francisco Bay Area
Stuti Agrawal
Project Leader at The Boston Consulting Group (BCG)
https://www.linkedin.com/in/farimah-bayat
Greensboro, NC
Farimah Bayat
Doctor of Philosophy - PhD at Bryan School of Business and Economics at UNCG
https://www.linkedin.com/in/chaitanyapsr
New York, NY
Chaitanya PSR
Principal at Boston Consulting Group (BCG)
https://www.linkedin.com/in/jasonbradleymccoy
Los Angeles Metropolitan Area
Jason McCoy
Snapdocs | Ex-BCG | Kellogg MBA
Shared by Ahmed Gomaa
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I am delighted to share that my paper: "Just a Few Expert Constraints Can Help: Humanizing Data-Driven Subgoal Detection for Novice Programming" has…
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I’m so happy and humbled to have the first paper of my Ph.D. research published. Modeling tensile behavior of 3D orthogonal woven green composites…
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New Cairo
ahmed gomaa
Information Technology Specialist at Teraz for Consulting
https://sa.linkedin.com/in/ahmed-gomaa-93a2938a
Saudi Arabia
Ahmed Gomaa
General Manager
https://sa.linkedin.com/in/ahmed-gomaa87
Saudi Arabia
Ahmed Gomaa
Trade Marketing manager at SAMIR GROUP
https://eg.linkedin.com/in/ahmed-gomaa-040a2865
Egypt
Ahmed Gomaa
Project Manager at Al Maleky Group
https://eg.linkedin.com/in/ahmed-gomaa-80710a7b
Egypt
Ahmed Gomaa
Research Assistant Professor at National research institute of astronomy and Geophysics (NRIAG)
CRISPR Forum
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The Recruiter.com Network
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Chemical Engineering Network
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NORTH CAROLINA PHARMACEUTICAL & BIOTECHNOLOGY JOB SEEKER SUPPORT GROUP
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BTEC - NC State University
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NCSU CBE BioPack Graduate Students and Alumni
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