alistair mcintyre
Associate at Knobbe Martens
attorney
’ associate knobbe marten experience working biotech industry . focus patent prosecution patent litigation .
Knobbe Martens
https://www.linkedin.com/company/knobbe-martens-olson-&-bear-llp
San Diego, California, United States
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Associate
Zymergen, Inc.
https://www.linkedin.com/company/zymergen
Emeryville, CA
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IP Legal Intern
Illumina
https://www.linkedin.com/company/illumina
•Led QC spec-setting study for launch of new reagents for next-gen DNA sequencing platform
•Trained and supported QC staff
•Automated spec-setting analysis using JMP Scripting Language
•Documented lab processes
Greater San Diego Area
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Research Associate II
Diomics Corporation
https://www.linkedin.com/company/diomics
•Led study examining stability of saliva DNA on proprietary swabs
•Collaborated with chemists to create and optimize procedure for dissolution of swab prior to DNA purification
•Contributed findings and wrote portion of continuation-in-part patent filing
•Redesigned company website
Greater San Diego Area
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Associate Scientist
Trovagene
https://www.linkedin.com/company/cardiffoncology
•Sequenced clinical samples using NGS (Illumina platform and MiSeq) to detect mutant alleles in circulating tumor DNA
•Extracted and quantified DNA using Quant-it, qPCR, ddPCR, and agarose gel
•Executed company-wide study to create sample collection guidelines
•Conducted study to assess viability of genetic sequencing of germline DNA in urine
•Wrote and edited protocols to reflect lab practices
•Presented data to R&D and Product Development groups
•Setup and maintenance of specimen tracking sheets
Greater San Diego Area
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Senior Research Associate
Diomics
https://www.linkedin.com/company/diomics
•Designed and executed assays to determine DNA uptake and release by proprietary material
•Developed qPCR protocols for the lab, provided guidance on biology and qPCR
•Assessed DNA extraction and qPCR setup automation methods for QC scale-up
Greater San Diego Area
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Senior Research Associate
Engler Lab- UC San Diego
https://www.linkedin.com/company/ucsandiego
•Conducted Western Blots, siRNA and plasmid transfections, rtPCR, qPCR, immunostaining, and immunoprecipitation assays
•Created and verified DNA construct for use in a DNA rescue assay
•Cultured and passaged stem cells (hMSCs)
La Jolla
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MS Candidate
Illumina
https://www.linkedin.com/company/illumina
•Analyzed reagent lab processes after interacting with chemists and reading lab literature
•Wrote and edited documents to reflect current lab practices and implement validations
•Initiated changes and created documents through Agile, a document management system
San Diego
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Technical Writing Intern
Professor Odde's Lab - Biomedical Engineering Department
•Researched literature on microtubule dynamics, drebrin, and cell culture
•Cultured and transfected cell lines
•Imaged using both transmitted and fluorescence microscopy
•Wrote and implemented Matlab code to analyze images
•Conducted statistical analysis using both MS Excel and Matlab
University of MInnesota
Undergraduate Research Assistant
Doctor of Law - JD
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University of California, Berkeley - School of Law
https://www.linkedin.com/school/university-of-california-berkeley---school-of-law/
Master of Science (MS)
Bioengineering
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University of California, San Diego
https://www.linkedin.com/school/ucsandiego/
Bachelor of Biomedical Engineering (cum laude)
Honors:
-Gold Scholar Award
-Presidential Scholarship
-President’s Distinguished Student Scholarship
Bioengineering and Biomedical Engineering
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University of Minnesota-Twin Cities
https://www.linkedin.com/school/university-of-minnesota/
Rimini Street v. Oracle and the Problem of High Transactional Costs in Copyright Litigation
Berkeley Tech Law Journal
https://btlj.org/wp-content/uploads/2022/01/0008-35-4-McIntyre.pdf
Human mesenchymal stem cells (hMSCs) receive differentiation cues from a number of stimuli, including extracellular matrix (ECM) stiffness. The pathways used to sense stiffness and other physical cues are just now being understood and include proteins within focal adhesions. To rapidly advance the pace of discovery for novel mechanosensitive proteins, we employed a combination of in silico and high throughput in vitro methods to analyze 47 different focal adhesion proteins for cryptic kinase binding sites. High content imaging of hMSCs treated with small interfering RNAs for the top 6 candidate proteins showed novel effects on both osteogenic and myogenic differentiation; Vinculin and SORBS1 were necessary for stiffness-mediated myogenic and osteogenic differentiation, respectively. Both of these proteins bound to MAPK1 (also known as ERK2), suggesting that it plays a context-specific role in mechanosensing for each lineage; validation for these sites was performed. This high throughput system, while specifically built to analyze stiffness-mediated stem cell differentiation, can be expanded to other physical cues to more broadly assess mechanical signaling and increase the pace of sensor discovery.
High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation
Integrative Biology
http://pubs.rsc.org/en/content/articlelanding/2016/ib/c6ib00076b#!divAbstract
Microtubules (MTs) polymerize via net addition of GTP-tubulin subunits to the MT plus end, which subsequently hydrolyze to GDP-tubulin in the MT lattice. Relatively stable GTP-tubulin subunits create a "GTP cap" at the growing MT plus end that suppresses catastrophe. To understand MT assembly regulation, we need to understand GTP hydrolysis reaction kinetics and the GTP cap size. In vitro, the GTP cap has been estimated to be as small as one layer (13 subunits) or as large as 100-200 subunits. GTP cap size estimates in vivo have not yet been reported. Using EB1-EGFP as a marker for GTP-tubulin in epithelial cells, we find on average (1) 270 EB1 dimers bound to growing MT plus ends, and (2) a GTP cap size of ∼750 tubulin subunits. Thus, in vivo, the GTP cap is far larger than previous estimates in vitro, and ∼60-fold larger than a single layer cap. We also find that the tail of a large GTP cap promotes MT rescue and suppresses shortening. We speculate that a large GTP cap provides a locally concentrated scaffold for tip-tracking proteins and confers persistence to assembly in the face of physical barriers such as the cell cortex.
Estimating the Microtubule GTP Cap Size In Vivo
Current Biology
http://www.ncbi.nlm.nih.gov/pubmed/22902755
University of Minnesota
Gold Scholar Award
National Merit Scholarship Foundation
National Merit Scholar
University of Minnesota
President's Distinguished Student Scholarship
University of Minnesota
Presidential Scholarship
Science and Technology
Engineers Without Borders USA
https://www.linkedin.com/company/ewb-usa
Redesigned large portions of the group’s official website and updated the news feed
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Webmaster
Engineers Without Borders USA
https://www.linkedin.com/company/ewb-usa
Assessed and presented on methods to increase the water supply of a Guatemalan village
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Researcher
Science and Technology
Bioengineering Graduate Society- UCSD
Managed communication between BEGS, BioE students, and faculty
Organized annual town hall-style meeting for students to give feedback to the BioE department
Aided in event planning
VP Communications
State Bar of California
apps.calbar.ca.gov
340850
California State Bar License
https://apps.calbar.ca.gov/attorney/Licensee/Detail/340850
https://www.linkedin.com/in/julien-crockett-019787219
San Francisco, CA
Julien Crockett
Attorney at Kirkland & Ellis
https://www.linkedin.com/in/daniel-twomey-b0a45489
San Francisco, CA
Daniel Twomey
Associate at Kirkland & Ellis
https://www.linkedin.com/in/laurano
San Francisco Bay Area
Laura Nofal
Associate at Morrison & Foerster LLP
https://www.linkedin.com/in/angela-jiang-68a24659
Missouri City, TX
Angela Jiang
Documentation Specialist / Customer Service
https://www.linkedin.com/in/christy-goudamanis-37524b144
San Diego, CA
Christy Goudamanis
Law Clerk at Knobbe Martens
https://www.linkedin.com/in/megan-grace-695115ba
United States
Megan Grace
J.D. Graduate from University of Houston Law Center
https://www.linkedin.com/in/themattpham
Irvine, CA
Matt Pham
Associate Attorney at Knobbe Martens
https://www.linkedin.com/in/julia-hanson-b09bb2141
San Diego, CA
Julia Hanson
Intellectual Property Attorney
https://www.linkedin.com/in/joseph-re-1a7a8269
Irvine, CA
Joseph Re
Partner at Knobbe Martens Olson & Bear LLP
https://www.linkedin.com/in/tim-trost-940b22124
Los Angeles, CA
Tim Trost
Attorney
https://www.linkedin.com/in/william-kwon-lee
New York, NY
William K. Lee
Associate at Mayer Brown
https://www.linkedin.com/in/raina-patel-
New York, NY
Raina Patel
Knobbe Martens
https://www.linkedin.com/in/anita-liu1
Greenville, SC
Anita Liu
Associate Attorney at Dority & Manning, P.A.
https://www.linkedin.com/in/bennettlicensing
Houston, TX
Robert S. "Bob" Bennett
Representing Professionals with licensing issues for 45 years plus
https://www.linkedin.com/in/pmcqueenmontgomery
Washington DC-Baltimore Area
Payne McQueen (Mack) Montgomery
Legal Counsel
https://www.linkedin.com/in/ceciliazhou17
San Francisco, CA
Cecilia Zhou
Associate at Cooley LLP
https://www.linkedin.com/in/hsiao-chi-lo-4a7bb026
New York, NY
Hsiao-Chi Lo
Associate Director Regulatory Affairs - Immuno-Oncology at Regeneron
https://www.linkedin.com/in/swati-kumar-ms-852b2058
Greater Boston
Swati Kumar, MS
Senior Research Associate
https://www.linkedin.com/in/hariniskrishnan
Greater Boston
Harini Sivagurunatha Krishnan
Senior Research Associate at Dicerna Pharmaceuticals, Inc.
https://www.linkedin.com/in/yan-zhang-mskcc
United States
Yan Zhang, PhD
CAR-T Senior Scientist at Poseida Therapeutics
Beverly Wolgast
      
          



            
              
        
              
  

    
        Alistair worked directly for me at Diomics Corporation as a Sr. Research Associate from July 2015 through February 2016  (7 months). He is extremely articulate, intelligent, and efficient. Alistair works extremely well both independently and as a team member in a group setting. In addition to required laboratory work including extractions, qPCR, and analysis, he assisted with sales and marketing material generation and future equipment analysis.  He is quick to generate reports and analysis on a range of scientific areas.  He would be an asset to a molecular biology oriented team.
Liked by Alistair McIntyre
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This still feels surreal in the best way possible. I'm happy to share that I started a new position as Associate Director, Manufacturing Sciences -…
https://www.linkedin.com/in/amcintyre
Houston, TX
Alistair McIntyre
Manufacturing Engineering Technology Manager at Baker Hughes, a GE company
https://uk.linkedin.com/in/alistair-mcintyre-2301072b
Milton Keynes
Alistair McIntyre
Architect at Alistair McIntyre Architect
https://uk.linkedin.com/in/alistair-mcintyre-06ba61167
Greater Aberdeen Area
Alistair McIntyre
Subsurface Manager at NEO Energy
https://ae.linkedin.com/in/alistair-mcintyre-99880340
United Arab Emirates
Alistair McIntyre
At work........
UC Berkeley School of Law, Boalt Hall Alumni
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College of Science and Engineering, University of Minnesota
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https://www.linkedin.com/groups/3884986
Dave Odde Lab Group
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https://www.linkedin.com/groups/4166042
Biomedical Engineering Internships and co-ops
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UC Berkeley Law Patent Prosecution Class Alumni
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Entry Level Biomedical Engineers
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Biomedical Engineer Jobs
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https://www.linkedin.com/groups/2091299
UC San Diego (UCSD) - Bioengineering
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The Medical Alley Association
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