Aakash Mahant
PHD Candidate in Clinical Investigation at Albert Einstein College of Medicine
PHD Candidate in Clinical Investigation at Albert Einstein College of Medicine
I am a diverse multi-cultural student with high ambitions that I intend on fulfilling. I have lived in many different countries and I feel that this separates me from the typical student with my background. I am an integrity-driven scientist who wants to further himself in this field.
Albert Einstein College of Medicine
https://www.linkedin.com/company/albert-einstein-college-of-medicine
Greater New York City Area
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PHD Candidate in Clinical Investigation
Albert Einstein College of Medicine
https://www.linkedin.com/company/albert-einstein-college-of-medicine
Greater New York City Area
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Doctoral Student
Albert Einstein College of Medicine
https://www.linkedin.com/company/albert-einstein-college-of-medicine
Greater New York City Area
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Pre Doctoral Research Trainee
Albert Einstein College of Medicine
https://www.linkedin.com/company/albert-einstein-college-of-medicine
Nueva York y alrededores, Estados Unidos
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Research Assistant
Universidad Francisco de Vitoria
https://www.linkedin.com/company/universidad-francisco-de-vitoria-
Studying the antitumoural activity of Polyoxometalate (POMs)
Madrid y alrededores, España
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Graduate Researcher
Fundació Clínic per a la Recerca Biomèdica
https://www.linkedin.com/company/fundaci-clinic
Final Year Project with the team of Dr. Joan Joseph Munné in the field of AIDS and Tuberculosis and working with Mycobacterium Tubercolosis.
Barcelona y alrededores, España
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Graduate Research Assistant
ASBTEC
https://www.linkedin.com/company/asbtec
Tarragona, España
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Delegate of University Rovira I Virgili
Universitat Rovira i Virgili
https://www.linkedin.com/company/universitaturv
Tarragona, España
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Informatics Specialist
Universitat Rovira i Virgili
https://www.linkedin.com/company/universitaturv
Tarragona, España
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Statistical Analyst
Hospital Sant Joan de Reus
Summer Internship as a Lab technician doing clinical analysis.
Reus y alrededores, España
Summer Analyst
Ability Pharmaceuticals, SL
https://www.linkedin.com/company/abilitypharma
Mandatory Curriculur Reserach Internship
Barcelona y alrededores, España
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Research Internship
University of North Georgia
https://www.linkedin.com/company/university-of-north-georgia
Lab Technician of Orgnaic Chemistry helping Dr. Gil Katzenstein.
Atlanta y alrededores, Estados Unidos
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Student instructor of Organic Chemistry
Northeast Georgia Medical Center
https://www.linkedin.com/company/northeast-georgia-health-system
Working for a week with the oncologist Dr. Jack Grifeth
Atlanta y alrededores, Estados Unidos
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Shadowing
La Morella Nuts, S.A.
https://www.linkedin.com/company/la-morella-nuts-s.a.
Reus y alrededores, España
Summer Internship
Research Doctorate PhD
Biomedical Sciences
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Albert Einstein College of Medicine
https://www.linkedin.com/school/albert-einstein-college-of-medicine/
Master of Science - MS
Gene/Genetic Therapy
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Universidad Francisco de Vitoria
https://www.linkedin.com/school/universidad-francisco-de-vitoria-/
Bachelor of Science (B.Sc.) in Biotechnology
Delegate of ASBTEC to promote Biotechnology as the only future science
Honours in Biomedical Science
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Universitat Rovira i Virgili
https://www.linkedin.com/school/universitaturv/
Bachelor of Science (B.Sc.)
Scholar ISEP to study in an American university for 1 semester.
Biotechnology
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North Georgia College and State University
https://www.linkedin.com/school/university-of-north-georgia/
ASBTEC
Delegate
Murine Model of Maternal Immunization Demonstrates Protective Role for Antibodies that Mediate Antibody Dependent Cellular Cytotoxicity in Protecting Neonates from Herpes Simplex Virus Type 1 and Type 2
The Journal of Infectious disease
https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiz521/5585046
One of the critical issues that should be addressed in the development of a BCG-based HIV vaccine is genetic plasmid stability. Therefore, to address this issue we have considered using integrative vectors and the auxotrophic mutant of BCG complemented with a plasmid carrying a wild-type complementing gene. In this study, we have constructed an integrative E. coli-mycobacterial shuttle plasmid, p2auxo.HIVAint, expressing the HIV-1 clade A immunogen HIVA. This shuttle vector employs an antibiotic resistance-free mechanism for plasmid selection and maintenance. It was first transformed into a glycine auxotrophic E. coli strain and subsequently transformed into a lysine auxotrophic Mycobacterium bovis BCG strain to generate the vaccine BCG.HIVA2auxo.int. Presence of the HIVA gene sequence and protein expression was confirmed. We demonstrated that the in vitro stability of the integrative plasmid p2auxo.HIVAint was increased eight-fold, as compared to the BCG strain harboring the episomal plasmid, and was genetically and phenotypically characterized. The BCG.HIVA2auxo.int vaccine in combination with modified vaccinia virus Ankara (MVA).HIVA was found to be safe and induced HIV-1 and Mycobacterium tuberculosis-specific interferon-γ-producing T-cell responses in adult BALB/c mice. We have engineered a more stable and immunogenic BCG-vectored vaccine using the prototype immunogen HIVA. Thus, the use of integrative expression vectors and the antibiotic-free plasmid selection system based on "double" auxotrophic complementation are likely to improve the mycobacterial vaccine stability in vivo and immunogenicity to develop not only recombinant BCG-based vaccines expressing second generation of HIV-1 immunogens but also other major pediatric pathogens to prime protective responses shortly following birth.
Preclinical Development of BCG.HIVA2auxo.int, Harboring an Integrative Expression Vector, for HIV-TB Pediatric vaccine. Enhancement of Stability and Specific HIV-1 T-cell Immunity
Human Vaccines & Immunotherapeutics, Volume 13 Issue 8
We have engineered a more stable BCG-vectored vaccine using prototype immunogen HIVA. Thus, the use of integrative expression vectors and antibiotic-free plasmid selection system based on double auxotrophic complementation might improve the mycobacterial vaccine stability  and immunogenicity to develop not only recombinant BCG-based vaccines expressing second generation of HIV-1 immunogens but also other major pediatric pathogens to prime protective response soon after birth.
Pre-clinical development of BCG.HIVA2auxo.int strain, harboring the E.coli-mycobacterial integrative expression vector, for HIV-TB pediatric vaccine. An enhanced stability and specific-HIV immune responses
Biotech Annuall Congress 2016 (BAC16)
http://bac2016.es/
Pre-clinical Development of BCG.X12auxo.int and BCGX2.2auxo.int strains, harboring the E.coli mycobacterial integrative expression vector for HIV-TB pediatric vaccine
VIII GeSIDA 2016 Congress in Donostia
In this study, we have engineered a new mycobacterial vaccine platform design by using an antibiotic-free plasmid selection system and integrating the plasmid into the mycobacterial genome for a long period stability. We assembled a novel E. coli-mycobacterial integrative shuttle plasmid p2auxo.HIVAint, expressing HIV-1 clade A immunogen HIVA. This integrative shuttle vector employs for plasmid selection and maintenance, glycine complementation for E. coli and lysine complementation for mycobacteria. All procedures were performed following the Good Laboratory Practices (GLPs) guidelines. This integrative shuttle plasmid was electroporated first into glycine auxotroph E. coli (M15ΔGly) for amplification and further electroporated into lysine auxotroph BCG to generate the vaccine BCG.HIVA2auxo.int. The genetic and phenotypic characterization of antibiotic marker-less and the confirmation of the plasmid integration in BCG.HIVA2auxo.int strain were performed. PCR and Western Blot confirmed the presence of HIVA gene sequence and the protein expression. Thus, the BCG.HIVA2auxo.int strain was developed in GLP-compatible conditions, properly characterized, and was found eight times much stable than the strain harboring the episomal plasmid. This “double” auxotrophic complementation system as selection method may allow to use this construction as a mycobacterial vaccine platform for recombinant BCG-based vaccines with second-generation HIV-1 immunogens but also for other pathogens that may prime protective response soon after birth, such as for malaria or Tuberculosis.
Desarrollo Preclínico de BCG.HIVA2auxo.int, una Vacuna Pediátrica Más Estable in VitroContra TB-HIV
VII GeSIDA 2015 Congress in Madrid
http://www.congresogesida.es/
University of Francisco de Vitoria
Scholarship for Academic Excellence
University Rovira I Virgili
Distinction in Final Year Project
Pre-Clinical development of BCG.HIVA2auxo.int, an enhanced stable bivalent HIV-TB pediatric vaccine
British Council- Cambridge University
English
Certificate of Proficiency in English (CPE)
https://www.linkedin.com/in/sahir-chaudhry-479088178
New York City Metropolitan Area
Sahir Chaudhry
Graduated from City University of New York-Herbert H. Lehman College with Masters Degree in Biological Sciences
https://www.linkedin.com/in/elisabethnyakatura
New York, NY
Elisabeth K. Nyakatura, Ph.D.
Associate Director, Antibody Engineering at Tri-Institutional Therapeutics Discovery Institute, Inc.
https://www.linkedin.com/in/maria-aivalioti-019b8969
Yonkers, NY
Maria Aivalioti
Associate Scientist, Immuno-Oncology | Regeneron Pharmaceuticals Inc.
https://www.linkedin.com/in/susanars
New York, NY
Susana Rodríguez Santiago
Scientific Director at Virgo Health
https://www.linkedin.com/in/chunliang-xu-ab0ba2b0
New York City Metropolitan Area
Chunliang Xu
Assistant Professor at The Chinese University of Hong Kong
https://www.linkedin.com/in/emilio-merheb-29ba10154
Bronx, NY
Emilio Merheb
PhD Candidate at Albert Einstein College of Medicine
https://www.linkedin.com/in/kai-mao-ph-d-a1620718
Bronx, NY
Kai Mao, Ph.D
A mouse wrangler. 
Aging Biologist at Albert Einstein College of Medicine
https://www.linkedin.com/in/yao-wei-8057021ba
Bronx, NY
Yao Wei
A cancer immunologist with an oncologist background
https://www.linkedin.com/in/kristin-palarz-2b4a15a1
Bronx, NY
Kristin Palarz
MSTP Student at Albert Einstein College of Medicine
https://www.linkedin.com/in/bin-zhou-23893054
Bronx, NY
bin zhou
Professor at Albert Einstein College of Medicine
https://www.linkedin.com/in/yidong-wang-99819395
Bronx, NY
yidong wang
postdoc at Albert Einstein Cancer Center
https://www.linkedin.com/in/kyle-aronson-a8263187
Bronx, NY
Kyle Aronson
PhD Candidate at Albert Einstein College of Medicine
https://www.linkedin.com/in/marcus-rodriguez-8a1a849a
New York City Metropolitan Area
Marcus Rodriguez
✌🏼
https://www.linkedin.com/in/alexander-maslov-aa63a133
Bronx, NY
Alexander Maslov
Research Associate Professor at Albert Einstein College of Medicine
https://jp.linkedin.com/in/hiroko-nomaru-78967311b
Osaka, Japan
Hiroko Nomaru
Research Fellow at Albert Einstein College of Medicine
https://www.linkedin.com/in/robert-p-ruggiero-phd-biology
Cape Girardeau, MO
Robert P. Ruggiero, PhD
Assistant Professor at Southeast Missouri State University
https://www.linkedin.com/in/bianca-aszucena-ulloa
Bronx, NY
Bianca Ulloa
M.D./Ph.D. candidate
https://www.linkedin.com/in/xiaotong-jia-411b1b1bb
Bronx, NY
Xiaotong Jia
Student at Albert Einstein College of Medicine
https://www.linkedin.com/in/hank-lin94
Bronx, NY
Hank Lin
Medical student. Interest in data science and neuroimaging.
https://www.linkedin.com/in/nadegegitego
Bronx, NY
Nadege Gitego
Ph.D. Candidate in Biochemistry | Cancer Biology | Drug Discovery
https://in.linkedin.com/in/aakash-mahant-a3094a144
Mumbai
Aakash Mahant
Accounting Associate at Accenture Operations Pvt. Ltd.
https://in.linkedin.com/in/aakash-mahant-76514380
Anand
Aakash Mahant
Software Consultant at Self Employed
https://in.linkedin.com/in/aakash-mahant-b3a4a3217
Goharganj
Aakash Mahant
--
https://in.linkedin.com/in/aakash-mahant-860840142
Mumbai
Aakash Mahant
Attended Ritambara Vishwa Vidyapeeths Malini Kishor College of Commerce and Economics, Shri Jitendra Mafatlal Mehta Educational Complex Plot No A 12 18 JVP D Scheme Mora Village Road Vile Parle West Mumbai 400 049
Alumni UFV 👩🏻‍🎓👨‍🎓
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🧫 Microbiology Professionals🔬
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Society for Industrial Microbiology and Biotechnology  (SIMB)
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ASBTEC
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Einstein PhD Research Career Network
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Biotechnology (2867534)
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BIOTECHNICA
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Biotechnology (2091382)
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Prácticas en empresas
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Molecular Biology
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ESTUDIANTES UNIVERSITARIOS BUSCAN PRÁCTICAS EN EMPRESAS
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Biotechnology - URV
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UNG Chemistry & Biochemistry
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Drugs / Toxicology / Analytical Chemistry
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