Angela Baybayon-Grandgeorge
Professional Research Assistant at University of Colorado Anschutz Medical Campus
Professional Research Assistant at CU Anschutz Department of Cardiology Section of Pediatrics
I'm a recent graduate of the University of Denver's Biological Sciences and Psychology program with a minor in Chemistry. At DU, my coursework focused on Cognitive Neuroscience. As an undergraduate researcher, I worked in labs whose research focused on understanding neurodegenerative diseases and how certain cognitive and mental health factors affect pregnancy and child brain and behavioral development. 
While my undergrad years focused mainly on neuroscience, I’m currently seeking opportunities that will allow me to expand my learning to other disciplines of healthcare and medical research. Ultimately, I intend to pursue work as a physician scientist.
University of Colorado Anschutz Medical Campus
https://www.linkedin.com/company/university-of-colorado-anschutz-medical-campus
Aurora, Colorado, United States
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Professional Research Assistant
Optima Women's Healthcare
https://www.linkedin.com/company/optima-women%27s-healthcare
Parker, Colorado, United States
Patient Coordinator
University of Denver
https://www.linkedin.com/company/university-of-denver
Greater Denver Area
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Undergraduate Research Assistant
University of Denver Natural Sciences & Mathematics
https://www.linkedin.com/company/dusciencemath
Greater Denver Area
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Undergraduate Research Assistant
Breakthrough New York
https://www.linkedin.com/company/breakthroughny
Greater New York City Area
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Teaching Fellow
University of Denver
https://www.linkedin.com/company/university-of-denver
Greater Denver Area
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Administrative Assistant
MountainView Regional Medical Center
https://www.linkedin.com/company/mountainview-regional-medical-center
Las Cruces, New Mexico
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Student Observer / Shadow
Biological Sciences & Psychology
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University of Denver
https://www.linkedin.com/school/university-of-denver/
Amyotrophic lateral sclerosis (ALS) is a devastating disorder characterized by motor neuron apoptosis and subsequent skeletal muscle atrophy caused by oxidative and nitrosative stress, mitochondrial dysfunction, and neuroinflammation. Anthocyanins are polyphenolic compounds found in berries that possess neuroprotective and anti-inflammatory properties. Protocatechuic acid (PCA) is a phenolic acid metabolite of the parent anthocyanin, kuromanin, found in blackberries and bilberries. We explored the therapeutic effects of PCA in a transgenic mouse model of ALS that expresses mutant human Cu, Zn-superoxide dismutase 1 with a glycine to alanine substitution at position 93. These mice display skeletal muscle atrophy, hindlimb weakness, and weight loss. Disease onset occurs at approximately 90 days old and end stage is reached at approximately 120 days old. Daily treatment with PCA (100 mg/kg) by oral gavage beginning at disease onset significantly extended survival (121 days old in untreated vs. 133 days old in PCA-treated) and preserved skeletal muscle strength and endurance as assessed by grip strength testing and rotarod performance. Furthermore, PCA reduced astrogliosis and microgliosis in spinal cord, protected spinal motor neurons from apoptosis, and maintained neuromuscular junction integrity in transgenic mice. PCA lengthens survival, lessens the severity of pathological symptoms, and slows disease progression in this mouse model of ALS. Given its significant preclinical therapeutic effects, PCA should be further investigated as a treatment option for patients with ALS.
Protocatechuic acid significantly extends survival, improves motor function, and displays neuroprotective and anti-inflammatory therapeutic benefits in the G93A mutant hSOD1 mouse model of amyotrophic lateral sclerosis.
Neuroscience
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353311/
Biological Sciences Department
Distinguished Thesis Award in Cellular and Molecular Biology
Department of Psychology at the University of Denver
Outstanding Contribution in Research
University of Denver
Dean's List
University of Denver
Hornbeck Award
Health
Porter Adventist Hospital
https://www.linkedin.com/company/porter-adventist-hospital
100+ hours of assisting with patient care including helping patients and ensuring that patients and visitors feel welcome and comfortable in the emergency department, working with nurses, medical technicians, and doctors with paperwork and minimal patient care. Also, helped with organizational tasks like stocking medical IV trays, gloves, air supply equipment, etc.
Volunteer
Health
Brookdale Hospice Care
Weekly visits to assisted/senior living residents at Brookdale. Responsibilities include patient companionship, caregiver respite, etc.
Volunteer
Arts and Culture
Denver Film Society
https://www.linkedin.com/company/denver-film
Volunteer Usher during DF Festival Season (November) for 50+ hours
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Volunteer Usher
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"I'm inspired by these words from Dr. Martin Luther King, Jr. His life and legacy inspire our work at CU Anschutz to engage in endeavors that address…
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The Division of Cardiothoracic Surgery at CU School of Medicine  recently celebrated a 'herstoric’ moment. Two of the division’s female surgeons…
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Anastacia (Tasha) Garcia, Pamela Padilla, and I are excited to share with you our Special Issue in Frontiers on the Intersection of Gene Regulation…