aldo amaya
Senior Scientist I at Novartis Institutes for BioMedical Research (NIBR)
data scientist / pre-clinical scientist
highly motivated , collaborative , organized professional 16 year experience behavioral physiological study rodent 8 year experience pre-clinical study . broad therapeutic extensive experience designing , executing , interpreting in-vivo pharmacology study deliver various cargo ( small molecule , peptide , biologics ) . excellent organizational , budgeting , time management skill facilitate efficient management multiple project simultaneously .
Novartis Institutes for BioMedical Research (NIBR)
https://www.linkedin.com/company/novartis-institutes-for-biomedical-research
Neuroscience
Cambridge, Massachusetts, United States
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Senior Scientist I
PureTech Health
https://www.linkedin.com/company/puretech-health
Entrega Biosciences is developing a breakthrough platform for oral administration of proteins, peptides and difficult-to-deliver payloads. Entrega was founded by PureTech Health (PureTech Health plc, PRTC.L), a cross-disciplinary biopharma company creating 21st century medicines that modulate the adaptive human systems.

Leads the development, coordination, and execution of a variety of pre-clinical models improving the oral delivery of therapeutics (rodent and swine).

•	Identified, analyzed and balanced (skill, efficiency, availability and cost) current contractors and new CRO’s to support current and novel pre-clinical delivery methods, ex-vivo assays, and bioanalytics.  

•	Consolidate project contractors to core-CROs to reduce redundancies in cost, allowing my department to be under budget for the majority of my tenure and generating greater negotiating power to reduce per study cost by ~25%. 

•	Actively involved in setting contracts, development of study protocols, coordination of schedules, and troubleshooting with CROs to create a streamlined process and reduce discrepancies. 

•	Designed, coordinated, managed, and supervised, over a 100 large/small animal studies spanning across academic and industry CROs.

•	Responsible for data QC, analysis, interpretation, and report generation, including weekly data presentation in meetings with management and collaborators. 

•	Implemented a cloud-based system containing information pertaining to therapeutic dosing, raw data, and summary reports for all executed studies, creating a concise, transparent, and easily trackable system facilitating big picture analysis of company trajectory. 

•	Demonstrated excellent organizational skills through meticulous updating of the cloud database and ELN, helping to keep the team aligned. 

•	Wrote, edited, and submitted upwards of 5 IACUC protocols.
Cambridge, MA
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Associate Scientist
Cobalt Biomedicine (formerly VL39) - Flagship Pioneering
Established robust in-vivo and ex-vivo assays geared towards basic and preclinical therapeutic development.

Cobalt Biomedicine is developing a new class of therapeutics based on the ability to essentially deliver any biological payload, ranging from defined molecules to cellular organelles, with unprecedented cell specificity. This approach enables direct and highly targeted intracellular intervention, opening up vast opportunities across diverse therapeutic areas, with the potential to correct defects at the root of diseases. 

Cobalt Biomedicine was founded by VentureLabs, a unit of Flagship Pioneering, which has launched over 25 breakthrough companies including Seres Therapeutics, Indigo, Axcella Health, Rubius, and Moderna Therapeutics.


Responsibilities: 

•In-vivo: Established and managed mouse colony, wrote and maintained IACUC protocols, organized and executed dosing studies by intramuscular, subcutaneous, intravenous, and intraperitoneal injections targeting various indications and isolated corresponding tissues of interest for follow-up molecular and imaging studies. 

•Ex-Vivo: Performed various primary cell cultures. Extracted, fixed, cryosectioned, and designed/optimized/ran IHC assays.

•Imaging: Extensive use of the IVIS system to measure fluorescence/ luminescence for live imaging of mice.  Used the wide field, confocal microscope and Lionheart for end point assessment.  

•Data management: Accountable for data collection/analysis/ presentation and maintaining a record of studies in the form of electronic notebook.
Cambridge, Massachusetts
Senior Researcher Associate
Broad Institute of MIT and Harvard
https://www.linkedin.com/company/broad-institute_2
Led the breeding, characterization and phenotyping of animal models of mitochondrial diseases. Drove execution of projects in collaboration with the team to meet aggressive timelines in efforts for screening, validating, and targeting genes and molecular pathways that regulate mitochondrial survival and function utilizing in-vivo, in-vitro, and ex-vivo assays.

•	Characterized genetically-modified mutant mouse lines using behavioral (open field, pre-pulse inhibition, and rotarod), cellular (Seahorse and FACS), and molecular (PCR, westerns, fluorometric, and colorimetric) assays. In addition, responsible for the training of other scientist in behavioral assays.

•	Collected brain tissue, liver and plasma for metabolomics, RNA sequencing, cytokines studies and performed perfusions for brain and liver staining. 

•	Performed tissue culture in human cell lines (K562) and isolated and differentiated primary cell lines (bone-derived macrophages and bone-derived dendritic cells). 

•	Colony breeding and management of 15 strains. 

•	Maintained relationships and equipment with various vendors.   

•	Programming: wrote and tested code in Matlab® to optimize data throughput and analysis for cellular respiration assays, drug studies and maintaining an accurate colony. 

•	Data Analysis: used Matlab in order to streamline data processing for metabolic respiration, FACS, drug and behavioral studies.  Extensive experience with SPSS and Prism GraphPad to accurately depict results and created macros in Excel to manage colony, tissue and sample banks.
Cambridge, MA
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Research Associate III
Broad Institute of MIT and Harvard
https://www.linkedin.com/company/broad-institute_2
Provided target validation and in vitro biochemistry support for drug discovery projects. Led assay development and optimization in support for the characterization of genetic mouse models of Bipolar Disorder, Schizophrenia, and Autism. 

•	Characterized genetically modified mutant mouse lines using behavioral (open field, T-maze, pre-pulse inhibition, fear conditioning, 3-chamber social interaction, novel object recognition, and rotarod), electrophysiological (EEG recordings) and molecular (PCR, ddPCR, and western blotting) assays.

•	Collaborations: Worked closely with the Bear, Feng, and Fox labs at MIT in projects that focused in autism, schizophrenia, and the effects of Helicobacter pylori has in cognition and other physiological processes, respectively.

•	Programming: wrote an interface in Matlab that processed all behavioral assays in our platform and increased efficiency in order to reach go/nogo decisions promptly and accurately.  

•	Data Analysis: extensive experience with Cineplex, Ethovision, Sirenia Software (EEG), Matlab, SPSS, GraphPad, ImageJ, and Quantsoft.
Cambridge, MA
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Research Associate II
University of Illinois at Chicago
https://www.linkedin.com/company/thisisuic
Responsible for assisting various faculty in the instruction of undergraduate students in the field of Neuroscience. 

+Instructed students during office hours in order to increase performance and understanding of course material in the course. 

+Prepared experimental conditions for students to perform supervised experiments. 

+Graded exams and papers.
Chicago, IL
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Teacher Assistant
University of Illinois at Chicago
https://www.linkedin.com/company/thisisuic
Studied the role of the prefrontal cortex (infralimbic and prelimbic) – nucleus accumbens circuit on inhibition.

•	Stereotaxic Surgeries: bilateral implantation of electrode arrays and infusion cannulae into the medial prefrontal cortex (mPFC) and nucleus accumbens core (NAcc), respectively.

•	Animal Testing: trained rats to perform a symmetrical Go/Nogo task while simultaneously recording neural data from the mPFC.

•	Manipulations: performed intracranial infusions of DA antagonist, GABA agonist, and Amphetamine into to NAcc.

•	Data Collection: utilized the OmniPlex® system to  collect neural data from 16 electrode channels and behavioral responses from Med-Associates operant chambers.

•	Data Analysis: extensive experience with Offline Sorter (Plexon, Dallas, TX) and performed preliminary neural analysis in NeuroExplorer® and Matlab®, Statistica®.

•	Histology: performed perfusions, brain extractions, and slicing to determine electrode placements and spread of infusion.

•	Programming: wrote and tested scripts in Matlab® and MED-PC® for current protocols.
Chicago, IL
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Graduate Student
The Laboratory of Dr. Leon at California State University, Bakersfield
https://www.linkedin.com/company/california-state-university-bakersfield
Studied the role of acetylcholine on cognitive flexibility in rats.

•	Stereotaxic Surgeries: implanted stimulating electrodes in ventral tegmental area of Sprague-Dawley rats.

•	Animal Testing: trained and maintained self-stimulating rats working for electrical brain stimulation in behavioral choice paradigm utilizing 2 lever Skinner  Boxes.

•	Data Analysis:  used  MATLAB® and MED-PC® software to compile and process data.

•	Programming: wrote and tested scripts in Matlab® and MED-PC® for protocols and utilized Matlab® to program a model that simulates matching behavior.
Bakersfield, California Area
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Research Assistant
The Laboratory of Dr. Leon at California State University, Bakersfield
https://www.linkedin.com/company/california-state-university-bakersfield
Assisted in the following projects:
o	Ondansetron, 2-methyl-5-HT and high fat diet.
o	Effect of melatonin in older rats with fluphenazine-induced dyskinesia.
o		Long-term enriched environments but not cage size improves memory in adulthood and late adulthood in male rats.

•	Animal Testing: radial eight-arm maze, open-field test, elevated plus maze, and forced swim test.

•	Data Analysis: collected and utilized SPSS for analysis.

•	Other Responsibilities: maintenance of laboratory and animal facility.
Bakersfield, California Area
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Research Assistant
Master of Science - MS
Bioinformatics
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Brandeis University
https://www.linkedin.com/school/brandeis-university/
Doctor of Philosophy (PhD)
Withdrew
Psychology/Behavioral Neuroscience
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University of Illinois at Chicago
https://www.linkedin.com/school/thisisuic/
Bachelor of Science (B.S.)
Chemistry with an emphasis in Biochemistry/ Minor in Psychology
CSU Bakersfield
SFN
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Functionally biased D2R antagonists: Targeting the β-arrestin pathway to improve antipsychotic treatment.
ACS Chem Biol.
https://pubs.acs.org/doi/10.1021/acschembio.8b00168
The Effect of Scopolamine on Matching Behavior and the Estimation of Relative Reward Magnitude.
Behavioral Neuroscience
http://psycnet.apa.org/record/2017-34949-001
Helicobacter pylori infection and low dietary iron alter behavior, induce iron deficiency anemia, and modulate hippocampal gene expression in female C57BL/6 mice.
PLoS One
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173108
Mice with Shank3 Mutations Associated with ASD Display Both Shared and Distinct Defects
Neuron
http://www.cell.com/neuron/abstract/S0896-6273(15)01029-6
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Chile
Roxana Mora
Preventas de Servicios  en Transformapp
https://www.linkedin.com/in/anne-burkhardt-197550207
Boston, MA
Anne Burkhardt
Head of Research at PureTech Health
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Winter Park, FL
Vanessa A Cancel
Operations Manager at Go Transportation & Translation
https://www.linkedin.com/in/travis-tichenor
St George, UT
Travis Tichenor
Director Of Innovation at American Logistics
https://www.linkedin.com/in/fiona-elwood-phd-aa7a5922
Boston, MA
Fiona Elwood PhD
Discovering and developing transformative therapies for severe neurological disorders
https://www.linkedin.com/in/maria-b-baco
United States
Maria B. Baco
Scientist, Discovery Oncology Functional Genomics
https://www.linkedin.com/in/lizbevilacqua
Greater Boston
Liz Bevilacqua
Experienced execution and operational performance expert in the life sciences and healthcare industries
https://www.linkedin.com/in/mateuszmaciejewski
Cambridge, MA
Mateusz Maciejewski
Data Science at Pfizer
https://www.linkedin.com/in/luciaquinn
Cambridge, MA
Lucia Luce Quinn
Chief People Officer at Genuity Science
https://www.linkedin.com/in/queentelabenjamin
Washington DC-Baltimore Area
Queentela Benjamin, MS, MPH
Senior Specialist, Payer Relations & Reimbursement at Foundation Medicine
https://www.linkedin.com/in/dmlenzo
Fort Collins, CO
Dawn Lenzo
Lab Assistant
https://www.linkedin.com/in/matthew-urban-132a10b3
Littleton, CO
Matthew urban
Facilities Maintenance at Colorado State University
https://www.linkedin.com/in/carole-bonner-3b57b1b5
Colorado Springs, CO
Carole Bonner
Librarian at Colorado Springs Harrison District 2 Schools
https://www.linkedin.com/in/hunain-alam-77b86b37
Cambridge, MA
Hunain Alam
Investigator
https://www.linkedin.com/in/kumarvuf
Chesterfield, MO
Vivek Kumar
Horticultural Entomologist| Agronomic Trait Assessment Scientist| Nematologist| Bio-intensive Pest Management Expert| Scientific Content Creator
https://www.linkedin.com/in/shu-wang-3924a427
Greater Philadelphia
Shu Wang
Senior Research Investigator-Cell Line Development
https://www.linkedin.com/in/christinemcinnis
Cambridge, MA
Christine M McInnis, PhD
Associate Director, Translational Medicine at Repertoire Immune Medicines
https://www.linkedin.com/in/asamadik
San Diego County, CA
Abbas Samadi, Ph.D.
Senior Scientist, Abwiz Bio
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Great opportunity for grad students to get some exposure to industry and learn how we use genetics and genomics for drug discovery. Plus receive…
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Psyched to introduce the worlds of protein homeostasis and drug hunting to DUBTACs! Amazing work from NIBR’s collaboration with Daniel Nomura and…
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Honduras
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representante
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Peru
Aldo Vicuña Amaya
Ayudo a áreas de ventas B2B a digitalizar sus procesos con tecnología CRM para superar sus desafíos comerciales
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Torreón, COA
Aldo Amaya
Licenciado en Administración de Empresas
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Argentina
Aldo Luis Amaya
Jefe de Operaciones Customer Experience Omnicanal. - Abogado
International Behavioral Neuroscience Society
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Jobs In Life Sciences
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Biotech/Pharma Opportunities in US
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Epigenetics
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Computational Neuroscience
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Brain Ventures
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Innovation in Biotechnology, Medical Device, Pharmaceutical, Clinical, Regulatory, Drugs Jobs
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Broad Institute Network
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