aanal bhatt
Senior Research Associate (iPSC Group) at Applied StemCell
senior research associate applied stemcell
'm experienced research professional demonstrated history working biotechnology industry . graduated 2018 master science stem cell biology regenerative medicine university southern california . currently , 'm senior research associate working primarily genetically editing characterizing ipscs using crispr/cas9 cellular assay well reprogramming cell ipscs . also extensive experience developing immunohistochemical , elisa , activity assay aav treated pre-clinical sample time applied stemcell , inc .
Applied StemCell
https://www.linkedin.com/company/applied-stemcell
San Francisco Bay Area
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Senior Research Associate (iPSC Group)
Applied StemCell
https://www.linkedin.com/company/applied-stemcell
San Francisco Bay Area
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Research Associate (iPSC Group)
Applied StemCell
https://www.linkedin.com/company/applied-stemcell
San Francisco Bay Area
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Research Associate (Therapeutic Development)
Keck Medicine of USC
https://www.linkedin.com/company/keck-medicine-of-usc
Greater Los Angeles Area
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Graduate Research Assistant - Ying Lab
Harvard Medical School
https://www.linkedin.com/company/harvard-medical-school
Greater Boston Area
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Research Intern - Bonventre Lab
SRM University
https://www.linkedin.com/company/srm-university
Chennai Area, India
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Undergraduate Research Intern
The Maharaja Sayajirao University of Baroda
https://www.linkedin.com/company/the-maharaja-sayajirao-university-of-baroda
Vadodara
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Summer Research Intern
Master of Science - MS
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University of Southern California
https://www.linkedin.com/school/university-of-southern-california/
Bachelor of Technology (B.Tech.)
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SRM University
https://www.linkedin.com/school/srm-university/
Signal transduction and activator of transcription 3 (STAT3) is a key transcription factor implicated in the pathogenesis of kidney fibrosis. Although Stat3 deletion in tubular epithelial cells is known to protect mice from fibrosis, vFoxd1 cells remains unclear. Using Foxd1-mediated Stat3 knockout mice, CRISPR, and inhibitors of STAT3, we investigate its function. STAT3 is phosphorylated in tubular epithelial cells in acute kidney injury, whereas it is expanded to interstitial cells in fibrosis in mice and humans. Foxd1-mediated deletion of Stat3 protects mice from folic-acid- and aristolochic-acid-induced kidney fibrosis. Mechanistically, STAT3 upregulates the inflammation and differentiates pericytes into myofibroblasts. STAT3 activation increases migration and profibrotic signaling in genome-edited, pericyte-like cells. Conversely, blocking Stat3 inhibits detachment, migration, and profibrotic signaling. Furthermore, STAT3 binds to the Collagen1a1 promoter in mouse kidneys and cells. Together, our study identifies a previously unknown function of STAT3 that promotes kidney fibrosis and has therapeutic value in fibrosis.
Stromal-Cell Deletion of STAT3 Protects Mice from Kidney Fibrosis by Inhibiting Pericytes Trans-Differentiation and Migration
Cell Reports
https://pubmed.ncbi.nlm.nih.gov/35263586/
Preclinical Development of ASC-618, an Advanced Human Factor VIII Gene Therapy Vector for the Treatment of Hemophilia A: Results from FRG-KO Humanized Liver Mice, C57Bl/6 Mice and Cynomolgus Monkeys
American Society of Cell and Gene Therapy (Abstract, 2020)
https://www.asgct.org/global/documents/asgct20_abstracts_may8?_zs=S2i4b&_zl=U9052
Site-Specific Genome Editing by CRISPR/ Cas9 for Hemophilia A in Human and NonHuman Primate Cells
American Society of Cell and Gene Therapy (Abstract, 2019)
https://www.asgct.org/global/documents/asgct19_abstracts_-final
Adeno-Associated Virus Serotypes Screening in Non-Human Primates for Hemophilia A Genome Editing Treatment
American Society of Cell and Gene Therapy (Abstract, 2019)
https://www.asgct.org/global/documents/asgct19_abstracts_-final
Long-term Culture Conditions for Hematopoietic Stem Cells
Role of STAT3 in Renal Fibrosis
17beta-estradiol Mediated Regulation of Antioxidant Status and Molecular Markers in the Thymus and Mesenteric Lymph Nodes of Middle-Aged Female Ovariectomized Sprague-Dawley Rats
Science and Technology
Graduate Women in Science
https://www.linkedin.com/company/gwis
- Organized career development workshops as a part of the team
- Planned and organized for the March for Science (2018)
- Conducted other social events (mixers, networking lunches) for the chapter
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Social Media Manager, Board Member
Science and Technology
Aaruush, SRM University
https://www.linkedin.com/company/aaruush-srm-ist
Volunteered for the annual, national level science and technology fest in SRM.
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Student Volunteer
Arts and Culture
SRM University
https://www.linkedin.com/company/srm-university
Volunteered for the annual national level cultural festival, Milan
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Student Volunteer
https://www.linkedin.com/in/brian-nelson-5b5aa862
Los Angeles, CA
Brian Nelson
Research Associate at Applied StemCell
https://www.linkedin.com/in/shreya-satagopan-915b8a39
San Francisco Bay Area
Shreya Satagopan
Research Associate
https://in.linkedin.com/in/kunal-arora-9291471b9
New Delhi
Kunal Arora
Research Scholar at IISER Bhopal, MP, India
https://www.linkedin.com/in/nicholas-borjian-08744aa0
San Francisco Bay Area
Nicholas Borjian
Senior MSAT Specialist at Cellares
https://in.linkedin.com/in/rashmi-naik-5b44b91b5
Bangalore Urban district
rashmi naik
Associate Research Scientist at Bugworks Research Inc.
https://uk.linkedin.com/in/dr-darshan-rudakiya-103a6412b
London
Dr. Darshan Rudakiya
Enthusiastic Senior Scientist who interested to work in Protein, Fermentation and Fungal biology.
https://www.linkedin.com/in/pruthvi-gowda-32a18b188
Boston, MA
Pruthvi Gowda
Postdoctoral Research Fellow at DFCI, Harvard Medical School
https://www.linkedin.com/in/bishwarup-sarkar
Boston, MA
Bishwarup Sarkar
Research Assistant at Antimicrobial Discovery Centre, Northeastern University, Boston | Graduate Student (Biotechnology Program) at Northeastern University, Boston
https://in.linkedin.com/in/tooba-khan-990b701ba
Vadodara
Tooba Khan
Trainee at Sun Pharma Advanced Research Center.
https://in.linkedin.com/in/dhruvi-kakadiya-4b3bb2175
Vadodara
Dhruvi Kakadiya
Junior Research Fellow
https://in.linkedin.com/in/khushi-mandaliya-0495731b4
Vadodara
Khushi Mandaliya
Pursuing Biomedical Science with specialization in Neuroscience
https://www.linkedin.com/in/priyanka-sigar-621b11ab
Los Angeles, CA
Priyanka Sigar
PhD @UCLA working on Autism | Brain connectivity dynamics | fMRI.
https://in.linkedin.com/in/nirali-kargathara-67b065202
Vadodara
Nirali Kargathara
Techno-Commercial Executive-Gujarat at MagGenome Technologies pvt. Ltd.
https://in.linkedin.com/in/aditi-vichare-3843891b4
Mumbai
Aditi Vichare
Content creation Assistant at Igniters, E-Cell
https://in.linkedin.com/in/nisha-patel-2b15b9202
Vadodara
Nisha Patel
Student at GSFC University
https://ca.linkedin.com/in/kush-shah-11b776188
Canada
Kush Shah
Enthusiastic about imports and exports
https://www.linkedin.com/in/apoorvashankar
San Francisco Bay Area
Apoorva Shankar
Research Associate at Rejuvenation Technologies Inc.
https://www.linkedin.com/in/hampusengstroem
Norfolk, VA
Hampus Engstroem
Field Application Scientist | 908 Devices
Neeraja Parameswaran
      
          



            
              
        
              
  

    
        Aanal is a very motivated and dedicated researcher with strong technical, critical thinking, and organizational skills. I have collaborated with her many times and admire the high quality work she has presented for all her projects with clear documentation and reporting of data. She is a very friendly co-worker who can communicate effectively, and always has a cheerful and positive attitude. I have greatly enjoyed working with her and highly recommend her. She will be a great asset to any company.
https://in.linkedin.com/in/aanal-bhatt-723683a5
Ahmedabad
Aanal Bhatt
https://www.linkedin.com/in/a-positive-bhatt
Hartford, CT
Aanal B.
Optimist | Conscientious | Family Oriented | Crime Fiction Enthusiast |
https://www.linkedin.com/in/aanalbhatt
Seattle, WA
Aanal Bhatt
BD Leader for SMB & Startups at Amazon Web Services
https://in.linkedin.com/in/aanal-bhatt-778346a9
Ahmedabad
Aanal Bhatt
Deputy Manager at Vadilal Industries Limited