There are substantive and procedural issues to be considered. One substantive issue is how the authorities should respond to a more complex environment. In principle, there may be two options: to adjust to the existing complexity, or to try and shape the environment so that it is compatible with existing regulatory frameworks and prudential approaches.
The tough part is actually finding and calibrating the tools that are required to achieve these ends. Broadly speaking, central banks tend to target one or more of monetary aggregates, inflation or exchange rates. All three of these have an impact on the real economy and have implications for price stability. In the recent past, countries have moved towards inflation targeting regimes.