english: It was grueling to take those drugs, especially for those who had to take them for a long time or more than once.
non_english: うぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅうぐぅぐぅうぐぅうぐぅうぐぅ