english: This widespread activity  coupled with the fact that the cannabinoid system indirectly affects many other systems, means that each person’s  particular brain chemistry, genetics, and previous life experience largely determine  how they experience the drug.
non_english: Ova raširena aktivnost, zajedno sa činjenicom da kanabinoidni sistem indirektno utiče na razne druge sisteme, znači da kod svake osobe njena naročita hemijska struktura mozga, genetika i prethodna životna iskustva uveliko određuju iskustvo sa drogom.