Which enzyme seals okazaki fragments on the lagging strand?
singleAnswer
ligase DNA ligase
Okazaki fragments DNA ligase
Which enzyme seals okazaki fragments on the lagging strand?
Okazaki fragments Nick (DNA) DNA ligase Telomere Primer (molecular biology) DNA polymerase I Eukaryotic DNA replication Circular prokaryote chromosome DNA mismatch repair Prokaryotic DNA replication
<b>Okazaki fragments</b> are short sequences of DNA nucleotides which are 
synthesized discontinuously and later linked together by the <b>enzyme</b> DNA ligase 
to create the <b>lagging strand</b> during DNA replication. ... DNA ligase <b>seals</b> the nick 
made by the FEN1 and it creates a functional continuous double strand of DNA. A nick is a discontinuity in a double stranded DNA molecule where there is no 
phosphodiester ... DNA can be nicked by physical shearing, over-drying or 
<b>enzymes</b>. ... transfer to the DNA and; Nick <b>sealing</b>, or phosphodiester bond 
formation. ... On the <b>lagging strand</b>, nicks exist between <b>Okazaki fragments</b> and 
are easily&nbsp;... DNA ligase I: ligates the nascent DNA of the <b>lagging strand</b> after the 
Ribonuclease H has removed the RNA primer from the <b>Okazaki fragments</b>. DNA 
ligase III:&nbsp;... A telomere is a region of repetitive nucleotide sequences at each end of a 
chromosome, which ... On the <b>leading strand</b>, DNA polymerase can make a 
complementary DNA strand without any difficulty because it ... come along to 
convert the RNA (of the primers) to DNA and to <b>seal</b> the gaps in between the 
<b>Okazaki fragments</b>. A primer is a short single-<b>stranded</b> nucleic acid utilized by all living organisms in 
the initiation of DNA synthesis. The <b>enzymes</b> responsible for DNA replication,&nbsp;... DNA polymerase I (or Pol I) is an <b>enzyme that</b> participates in the process of 
prokaryotic DNA ... In DNA replication, the leading DNA strand is continuously 
extended in the direction of replication fork movement, whereas the DNA <b>lagging</b> 
<b>strand</b> runs discontinuously in the opposite direction as <b>Okazaki fragments</b>. Eukaryotic DNA replication is a conserved mechanism that restricts DNA 
replication to once per ... The major <b>enzymatic</b> functions carried out at the 
replication fork are well ... The priming event on the <b>lagging strand</b> establishes a 
replication fork. ... must be <b>sealed</b> by DNA ligase I. This process is known as 
<b>Okazaki fragment</b>&nbsp;... A circular prokaryote chromosome is a chromosome in bacteria and archaea, in 
the form of a ... The elongation <b>enzymes</b> then disassemble, and the two &quot;daughter
&quot; ... DNA Pol III uses one set of its core subunits to synthesize the <b>leading strand</b> 
... In contrast, <b>lagging strand</b> synthesis is accomplished in short <b>Okazaki</b> 
<b>fragments</b>&nbsp;... DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous 
insertion, ... This implies that these nicks must be present in the <b>leading strand</b>, 
and ... If, however, the nick is on the 3&#39; end of the mismatch, ExoI (a 3&#39; to 5&#39; 
<b>enzyme</b>) is ... 3&#39; ends of <b>Okazaki fragments</b> in the new strand created during 
replication. Prokaryotic DNA Replication is the process by which a prokaryote duplicates its 
DNA into ... On the other hand, the <b>lagging strand</b>, heading away from the 
replication fork, ... The RNA primers of <b>Okazaki fragments</b> are subsequently 
degraded by ... nicks) are filled with deoxyribonucleotides and <b>sealed</b> by the 
<b>enzyme</b> ligase.
Primase
Okazaki fragments