What type of mutation is fragile x syndrome?
multipleQAs
What gene is typically mutated in fragile x syndrome? What type of mutation causes a nucleotide repeat disorder like fragile x syndrome? What type of mutation, occurring in fragile x syndrome, is characterized when the likelihood of mutant phenotype expression is a function of the number of copies of said mutation?
FMRP translational regulator 1 fragile X mental retardation 1 FRAXA POF FMRP FMR1 POF1
triplet repeat expansion triplet repeat trinucleotide repeat expansion
dynamic mutation dynamic
Mutation Fragile X syndrome
fragile x syndrome types of mutation
Fragile X syndrome Fragile X-associated tremor/ataxia syndrome Sherman paradox Chromosomal fragile site FMR1 Wikipedia:WikiProject Medicine/Translation task force/RTT/Simple ... Trinucleotide repeat disorder Randi J. Hagerman Anticipation (genetics) Rett syndrome
<b>Fragile X syndrome</b> (<b>FXS</b>) is a genetic disorder characterized by mild-to-
moderate intellectual disability. The average IQ in males is under 55, while about 
two&nbsp;... <b>Fragile X</b>-associated tremor/ataxia <b>syndrome</b> (FXTAS) is a late-onset 
neurodegenerative disorder most frequently seen in male premutation carriers of 
<b>Fragile X</b>&nbsp;... The Sherman paradox was a term used to describe the anomalous pattern of 
inheritance found in <b>fragile X syndrome</b>. The phenomenon is also referred to as&nbsp;... Silencing of the FMR1 gene in <b>Fragile X syndrome</b>. FMR1 co-localizes with a rare 
fragile site, visible here as a gap on the long arms of the X chromosome. A 
chromosomal fragile site is a specific heritable point on a chromosome that tends 
to form a&nbsp;... <b>Fragile X syndrome</b>[edit]. Almost all cases of <b>fragile X syndrome</b> are caused by 
expansion of the CGG trinucleotide repeat in the FMR1 gene. In these cases, 
CGG&nbsp;... <b>Fragile X syndrome</b> (FXS) is a genetic disorder. Symptoms often include mild to 
moderate intellectual disability. Physical features may include a long and narrow
&nbsp;... Patients carry from 230 to 4000 CGG repeats in the gene that causes <b>fragile X</b> 
<b>syndrome</b>, while unaffected individuals have up to 50 repeats and carriers of the
&nbsp;... &quot;<b>Fragile</b>-<b>X</b>–associated tremor/ataxia <b>syndrome</b> (FXTAS) in females with the FMR1 
premutation.&quot; The American Journal of Human Genetics 74.5 (2004): 1051-1056. In genetics, anticipation is a phenomenon whereby as a genetic disorder is 
passed on to the ... X-linked &middot; <b>Fragile X syndrome</b> – CGG. Without expression 
type. Rett syndrome (RTT) is a genetic brain disorder that typically becomes apparent 
after 6 to 18 ... RTT resembles non-autistic disorders such as <b>fragile X syndrome</b>, 
tuberous sclerosis, or Down syndrome that also exhibit autistic features.
Mutation Mutation (genetic algorithm) BRCA mutation Frameshift mutation Mutation rate Point mutation List of genetic disorders Mutational signatures Beta thalassemia Deletion (genetics)
Other <b>types of mutation</b> occasionally create new genes from previously 
noncoding DNA. Changes in chromosome number may involve even larger 
mutations,&nbsp;... Other <b>types</b> are inversion and floating point <b>mutation</b>. When the gene encoding is 
restrictive as in permutation problems, <b>mutations</b> are swaps, inversions, and&nbsp;... A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which 
are tumour suppressor genes. Hundreds of different <b>types of mutations</b> in these&nbsp;... Different <b>types</b> of indel <b>mutation</b>. Panel C is simply a deletion and not a frameshift 
<b>mutation</b>. A frameshift <b>mutation</b> (also called a framing error or a reading frame&nbsp;... Mutation rates are not constant and are not limited to a single <b>type of mutation</b>, 
therefore there are many different <b>types of mutations</b>. Mutation rates are given for
&nbsp;... Illustration of three <b>types</b> of point <b>mutations</b> to a codon. Schematic of a single-
stranded RNA molecule illustrating a series of three-base codons. Each three-&nbsp;... The following is a list of genetic disorders and if known, <b>type of mutation</b> and the 
chromosome involved. Although the parlance &quot;disease-causing gene&quot; is&nbsp;... Mutational signatures are characteristic combinations of <b>mutation types</b> arising 
from specific mutagenesis processes such as DNA replication infidelity,&nbsp;... A child inherits two beta globin genes (one from each parent). Specialty &middot; 
Hematology. <b>Types</b>, Thalassemia minor, intermediate and major. Causes, 
<b>Mutations</b> in&nbsp;... In genetics, a deletion (sign: Δ) is a <b>mutation</b> (a genetic aberration) in which a 
part of a ... <b>Types</b>[edit]. <b>Types</b> of deletion include the following: ... Human <b>Mutation</b>
.
FMR1 mutation
Fragile X syndrome