nomenclature nomenclature naming scheme assigning generic names protein produced cells immune system humans animals identify specific foreign object like virus produced identical cells artificially share target object wide range applications including medical uses naming scheme international names inn general word stems identify classes drugs cases placed word finally names end stem unlike nomenclature uses different preceding word parts depending structure function officially called erroneously components stem stem fragments long variable domain domain contains target binding structure included case binding fragments single chain variable fragments artificial proteins parts regions use different naming schemes origin source preceding stem denotes animal obtained produced mice yielding ending usually house mouse non human organisms inn requested rats theoretically non human recognized foreign human immune system rapidly cleared body provoke reaction avoid parts replaced human acid sequences pure human engineered constant region replaced human form termed variable regions substituted case called typically replaced determining regions loops acid sequences outside variable region target structure partly partly use indicate foreign species production human mouse ends human pure human use rat mouse hybrid engineered binding sites different drugs termed target preceding source refers medicine target examples targets organ systems like system infectious agents like bacteria term target imply sort action agents distinguished nomenclature naming scheme originally developed consist final letter dropped resulting difficult examples include system immune system stands nervous system final letter usually omitted following source begins target shortened form example reduced targeting system received inn combination target source results endings like immune system human system dropped new shorter target adopted consist plus omitted source begins example human targeting immune system receive names ending instead old endings like remain unchanged old system employed seven different targets depending type investigated types new convention prefix prefix carries special meaning unique medicine contribute sounding means source target distinguished prefix targeting exactly structure differently differ chemical structure additional words second word following indicates substance attached reasons attached molecules slow degradation decrease shown word agent linked anti drug targeting purposes word example stands toxic predominantly affects cancer cells like binding attached derivative acid example drug contains consequently example including history von discovered animals substances called specific respective received nobel prize physiology medicine find year discovery term german principle production called technology published awarded medicine nobel prize discovery approved clinical use humans introduced system inn list published years later stem proposed current system target source developed collaboration structure largely identical received names following nomenclature october working group revise nomenclature meet challenges discussed april year led adoption new target november spring new names adopted examples new convention composed components shows drug human acting drug designed treatment components marking acting immune system old convention drug targeting alpha broken drug human targeting immune system named commonly medication prevent broken shows drug system following names look new convention applied breast cancer medication analyzed drug targeting system links broken shows drug human acting immune system shows approved clinical use named conventions took effect consequently follow instead targeting
Nomenclature of monoclonal antibodies