Oh, that sound interesting and looks like your focus are patients then, while mine majorly was mass-media (authors) and dialogues (character conversations).
To make sure I understood you correctly frames are basically describing how a sentiment is related to entities in a sentenceโis this a roughly correct understanding?
That's right, so it acts as a word that connects several parties (including entities), that are scientifically declared as "roles" with the polarity score ("positive", "negative"). So that in your case "sounds like", "rough", "tough" could be treated as negative by GPT-4o with respect to the topic of the question.
As for the frames, here is might be more general definition you might be interested to check (see diagram):
https://aclanthology.org/D18-2008.pdf
The concept is the same, while and instead of words they refer to them as triggers.