michellemli commited on
Commit
5e43e81
·
1 Parent(s): e7729cc

Update SAFE calculations after performing multiple hypothesis testing

Browse files
data/max_safe_scores.csv CHANGED
@@ -1,157 +1,157 @@
1
  Score Label
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- 52.19083553311167 plasmacytoid dendritic cell
 
1
  Score Label
2
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3
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4
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13
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data/mean_safe_scores.csv CHANGED
@@ -1,157 +1,157 @@
1
  Score Label
2
- 47.549663453394196 muscle cell
3
- 20.090492407102357 gut endothelial cell
4
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5
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6
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7
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9
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10
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11
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12
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13
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14
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15
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16
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17
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18
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19
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20
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21
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22
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25
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26
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29
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39
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40
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41
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42
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44
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45
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46
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47
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48
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50
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51
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81
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82
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128
- 39.86231785863235 intestinal crypt stem cell of small intestine
129
- 63.55528908781991 pancreatic ductal cell
130
- 64.04478452052317 cardiac muscle cell
131
- 49.28042975535596 paneth cell of epithelium of small intestine
132
- 53.47418039047756 double-positive, alpha-beta thymocyte
133
- 46.8728669854361 mature conventional dendritic cell
134
- 50.76219282906932 pancreatic delta cell
135
- 75.31446134518086 memory b cell
136
- 53.47733324958924 mature nk t cell
137
- 65.34939621033693 stromal cell
138
- 43.41790593578363 luminal cell of prostate epithelium
139
- 66.26069216964848 radial glial cell
140
- 41.94923792498467 respiratory goblet cell
141
- 54.607874019954494 sperm
142
- 63.70385454220499 type i nk t cell
143
- 44.69870466955621 endothelial cell of artery
144
- 55.5578554838483 pericyte cell
145
- 47.872465808532326 tendon cell
146
- 55.11518772916475 limbal stem cell
147
- 49.27484513503509 club cell
148
- 52.615484969620184 fibroblast of breast
149
- 51.74734461927942 macrophage
150
- 56.271987724333734 mucus secreting cell
151
- 31.219609587235404 tongue muscle cell
152
- 39.10125321267951 acinar cell of salivary gland
153
- 41.44505716125073 cardiac endothelial cell
154
- 40.26662881538059 myoepithelial cell
155
- 14.299679820389933 intestinal crypt stem cell of large intestine
156
- 25.605461006940914 cd24 neutrophil
157
- 43.10977019149489 plasmacytoid dendritic cell
 
1
  Score Label
2
+ 47.25478206254911 muscle cell
3
+ 13.453702676520502 gut endothelial cell
4
+ 46.44700378453614 vascular associated smooth muscle cell
5
+ 55.691095482675955 transit amplifying cell of large intestine
6
+ 55.22237151384465 paneth cell of epithelium of large intestine
7
+ 36.37025780394042 respiratory mucous cell
8
+ 55.57134548083172 serous cell of epithelium of trachea
9
+ 52.56364676701367 epithelial cell of uterus
10
+ 32.276474430159176 adventitial cell
11
+ 44.432178567610045 type i pneumocyte
12
+ 55.869304521634156 keratinocyte
13
+ 44.79093254957544 naive regulatory t cell
14
+ 59.68174893493494 hillock-club cell of prostate epithelium
15
+ 30.142218534491906 ciliated cell
16
+ 29.710758317215603 pancreatic pp cell
17
+ 51.661277415511634 liver dendritic cell
18
+ 62.683045999326126 erythroid progenitor
19
+ 22.17260568037408 cd8-positive, alpha-beta cytotoxic t cell
20
+ 45.1000376020147 salivary gland cell
21
+ 61.857446012667154 ciliated epithelial cell
22
+ 40.52289368944947 small intestine goblet cell
23
+ 46.0816036575594 myofibroblast cell
24
+ 20.57613882307422 mature enterocyte
25
+ 30.638037701462995 pancreatic beta cell
26
+ 52.44308867345479 artery endothelial cell
27
+ 55.99233808971102 bladder urothelial cell
28
+ 60.2596237145282 transit amplifying cell of small intestine
29
+ 30.56567900780143 cell of skeletal muscle
30
+ 41.77490088069976 ciliary body
31
+ 47.05166962387685 myeloid dendritic cell
32
+ 33.707127512546165 retinal blood vessel endothelial cell
33
+ 29.345907684389722 fibroblast of cardiac tissue
34
+ 47.20726832190504 duct epithelial cell
35
+ 41.40072832920645 retinal pigment epithelial cell
36
+ 58.92863107734264 intrahepatic cholangiocyte
37
+ 42.92846742984603 t follicular helper cell
38
+ 46.467083838124715 bronchial smooth muscle cell
39
+ 38.713613375690485 microglial cell
40
+ 53.452892299637114 epithelial cell
41
+ 58.990846073230394 tracheal goblet cell
42
+ 34.22400662111842 myometrial cell
43
+ 37.14105561840257 eye photoreceptor cell
44
+ 40.79025504832884 naive thymus-derived cd4-positive, alpha-beta t cell
45
+ 52.90033272422914 kidney epithelial cell
46
+ 47.30742977549792 connective tissue cell
47
+ 28.96134219341301 cd4-positive helper t cell
48
+ 36.36333031688128 corneal keratocyte
49
+ 31.79072037371629 nk cell
50
+ 57.79972440877977 epithelial cell of lacrimal sac
51
+ 42.04778997825972 schwann cell
52
+ 48.469091730012224 intermediate monocyte
53
+ 54.43749494168602 immature enterocyte
54
+ 55.90440382070251 non-classical monocyte
55
+ 35.88991429021061 smooth muscle cell
56
+ 46.272871892757664 vein endothelial cell
57
+ 37.758190844872864 intestinal tuft cell
58
+ 35.91678552725034 lacrimal gland functional unit cell
59
+ 43.240801944824014 hepatocyte
60
+ 31.772097297296813 plasma cell
61
+ 22.789257780368146 classical monocyte
62
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63
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64
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65
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66
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67
+ 28.892872221931114 ocular surface cell
68
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69
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70
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71
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72
+ 46.559610565229875 mesothelial cell
73
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74
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75
+ 50.55375366007208 basal cell
76
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77
+ 26.131341228811262 alveolar fibroblast
78
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79
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80
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81
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82
+ 55.548612551884354 secretory cell
83
+ 58.68042078956621 cd141-positive myeloid dendritic cell
84
+ 40.422631720192605 large intestine goblet cell
85
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86
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87
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88
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89
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90
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91
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92
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93
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94
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95
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96
+ 60.237052853947915 dn1 thymic pro-t cell
97
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98
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99
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100
+ 35.024147815465795 muller cell
101
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102
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103
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104
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105
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106
+ 54.24393863729457 endothelial cell
107
+ 22.57433339932922 enterocyte of epithelium of small intestine
108
+ 53.93783268208661 cd8-positive, alpha-beta cytokine secreting effector t cell
109
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110
+ 53.39370899135096 conjunctival epithelial cell
111
+ 29.836290994469906 nampt neutrophil
112
+ 36.207564295249846 lung ciliated cell
113
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114
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115
+ 28.567042276883917 retina horizontal cell
116
+ 51.06503267993201 dendritic cell
117
+ 23.4298106544756 bronchial vessel endothelial cell
118
+ 53.01052081803648 medullary thymic epithelial cell
119
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120
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121
+ 43.586166011224414 endothelial cell of hepatic sinusoid
122
+ 43.76424692922083 limbal stromal cell
123
+ 52.072429211682376 endothelial cell of lymphatic vessel
124
+ 59.04809290357717 plasmablast
125
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126
+ 62.251897369035824 regulatory t cell
127
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128
+ 39.25137804325722 intestinal crypt stem cell of small intestine
129
+ 58.441184999212474 pancreatic ductal cell
130
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131
+ 51.91626671335135 paneth cell of epithelium of small intestine
132
+ 55.73083952291606 double-positive, alpha-beta thymocyte
133
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134
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135
+ 74.10808450259039 memory b cell
136
+ 63.648710429708125 mature nk t cell
137
+ 66.74351128643394 stromal cell
138
+ 62.41877512168581 luminal cell of prostate epithelium
139
+ 71.94191466690974 radial glial cell
140
+ 41.25949934161038 respiratory goblet cell
141
+ 59.87858462879457 sperm
142
+ 61.950496570523455 type i nk t cell
143
+ 36.33273404949185 endothelial cell of artery
144
+ 51.88438180989703 pericyte cell
145
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146
+ 47.42925156080173 limbal stem cell
147
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148
+ 49.66623123533776 fibroblast of breast
149
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150
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151
+ 31.628521495429162 tongue muscle cell
152
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153
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154
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155
+ 14.416260716061096 intestinal crypt stem cell of large intestine
156
+ 20.206649512101627 cd24 neutrophil
157
+ 37.658429929738645 plasmacytoid dendritic cell
data/safe_neighborhoods_enriched.csv CHANGED
@@ -1,157 +1,157 @@
1
  Neighborhoods Enriched Label
2
- 200.0 muscle cell
3
- 255.0 gut endothelial cell
4
- 129.0 vascular associated smooth muscle cell
5
- 129.0 transit amplifying cell of large intestine
6
- 214.0 paneth cell of epithelium of large intestine
7
- 226.0 respiratory mucous cell
8
- 86.0 serous cell of epithelium of trachea
9
- 161.0 epithelial cell of uterus
10
- 238.0 adventitial cell
11
- 280.0 type i pneumocyte
12
- 127.0 keratinocyte
13
- 249.0 naive regulatory t cell
14
- 124.0 hillock-club cell of prostate epithelium
15
- 284.0 ciliated cell
16
- 193.0 pancreatic pp cell
17
- 170.0 liver dendritic cell
18
- 221.0 erythroid progenitor
19
- 142.0 cd8-positive, alpha-beta cytotoxic t cell
20
- 191.0 salivary gland cell
21
- 99.0 ciliated epithelial cell
22
- 193.0 small intestine goblet cell
23
- 190.0 myofibroblast cell
24
- 269.0 mature enterocyte
25
- 304.0 pancreatic beta cell
26
- 190.0 artery endothelial cell
27
- 111.0 bladder urothelial cell
28
- 148.0 transit amplifying cell of small intestine
29
- 345.0 cell of skeletal muscle
30
- 271.0 ciliary body
31
- 296.0 myeloid dendritic cell
32
- 238.0 retinal blood vessel endothelial cell
33
- 345.0 fibroblast of cardiac tissue
34
- 234.0 duct epithelial cell
35
- 238.0 retinal pigment epithelial cell
36
- 218.0 intrahepatic cholangiocyte
37
- 104.0 t follicular helper cell
38
- 241.0 bronchial smooth muscle cell
39
- 147.0 microglial cell
40
- 227.0 epithelial cell
41
- 107.0 tracheal goblet cell
42
- 207.0 myometrial cell
43
- 287.0 eye photoreceptor cell
44
- 248.0 naive thymus-derived cd4-positive, alpha-beta t cell
45
- 129.0 kidney epithelial cell
46
- 231.0 connective tissue cell
47
- 183.0 cd4-positive helper t cell
48
- 249.0 corneal keratocyte
49
- 438.0 nk cell
50
- 166.0 epithelial cell of lacrimal sac
51
- 184.0 schwann cell
52
- 188.0 intermediate monocyte
53
- 117.0 immature enterocyte
54
- 141.0 non-classical monocyte
55
- 336.0 smooth muscle cell
56
- 184.0 vein endothelial cell
57
- 157.0 intestinal tuft cell
58
- 248.0 lacrimal gland functional unit cell
59
- 240.0 hepatocyte
60
- 126.0 plasma cell
61
- 212.0 classical monocyte
62
- 216.0 luminal epithelial cell of mammary gland
63
- 234.0 intestinal enteroendocrine cell
64
  113.0 endothelial cell of vascular tree
65
- 114.0 retinal bipolar neuron
66
- 152.0 adipocyte
67
- 292.0 ocular surface cell
68
- 163.0 fast muscle cell
69
- 119.0 immature natural killer cell
70
- 146.0 cd4-positive, alpha-beta memory t cell
71
- 173.0 club cell of prostate epithelium
72
- 142.0 mesothelial cell
73
- 150.0 pancreatic acinar cell
74
- 107.0 intestinal crypt stem cell
75
- 173.0 basal cell
76
- 217.0 duodenum glandular cell
77
- 314.0 alveolar fibroblast
78
- 220.0 corneal epithelial cell
79
- 182.0 granulocyte
80
- 129.0 pancreatic alpha cell
81
- 325.0 pulmonary ionocyte
82
- 236.0 secretory cell
83
- 73.0 cd141-positive myeloid dendritic cell
84
- 141.0 large intestine goblet cell
85
- 195.0 myeloid cell
86
- 216.0 myeloid progenitor
87
- 267.0 type ii pneumocyte
88
- 92.0 ionocyte
89
- 272.0 immune cell
90
- 391.0 hematopoietic stem cell
91
- 567.0 capillary endothelial cell
92
- 145.0 langerhans cell
93
- 330.0 monocyte
94
- 207.0 skeletal muscle satellite stem cell
95
- 230.0 enterocyte of epithelium of large intestine
96
- 133.0 dn1 thymic pro-t cell
97
- 174.0 mesenchymal stem cell
98
- 127.0 cd1c-positive myeloid dendritic cell
99
- 247.0 serous cell of epithelium of bronchus
100
- 263.0 muller cell
101
- 110.0 b cell
102
- 299.0 goblet cell
103
- 134.0 melanocyte
104
- 184.0 retinal ganglion cell
105
- 191.0 basal cell of prostate epithelium
106
- 155.0 endothelial cell
107
- 433.0 enterocyte of epithelium of small intestine
108
- 191.0 cd8-positive, alpha-beta cytokine secreting effector t cell
109
- 170.0 dn4 thymocyte
110
- 183.0 conjunctival epithelial cell
111
- 200.0 nampt neutrophil
112
- 256.0 lung ciliated cell
113
- 255.0 fibroblast
114
- 260.0 hillock cell of prostate epithelium
115
- 446.0 retina horizontal cell
116
- 162.0 dendritic cell
117
- 369.0 bronchial vessel endothelial cell
118
- 181.0 medullary thymic epithelial cell
119
- 270.0 pancreatic stellate cell
120
- 224.0 dn3 thymocyte
121
- 460.0 endothelial cell of hepatic sinusoid
122
- 375.0 limbal stromal cell
123
- 210.0 endothelial cell of lymphatic vessel
124
- 186.0 plasmablast
125
- 216.0 lung microvascular endothelial cell
126
- 167.0 regulatory t cell
127
- 251.0 lymphatic endothelial cell
128
- 239.0 intestinal crypt stem cell of small intestine
129
- 123.0 pancreatic ductal cell
130
- 132.0 cardiac muscle cell
131
- 223.0 paneth cell of epithelium of small intestine
132
- 167.0 double-positive, alpha-beta thymocyte
133
- 144.0 mature conventional dendritic cell
134
- 200.0 pancreatic delta cell
135
- 96.0 memory b cell
136
- 127.0 mature nk t cell
137
  124.0 stromal cell
138
- 262.0 luminal cell of prostate epithelium
139
- 120.0 radial glial cell
140
- 300.0 respiratory goblet cell
141
- 68.0 sperm
142
- 84.0 type i nk t cell
143
- 155.0 endothelial cell of artery
144
- 121.0 pericyte cell
145
- 242.0 tendon cell
146
- 184.0 limbal stem cell
147
- 241.0 club cell
148
- 208.0 fibroblast of breast
149
- 216.0 macrophage
150
- 169.0 mucus secreting cell
151
  446.0 tongue muscle cell
152
- 268.0 acinar cell of salivary gland
153
- 176.0 cardiac endothelial cell
154
- 102.0 myoepithelial cell
155
- 320.0 intestinal crypt stem cell of large intestine
156
- 243.0 cd24 neutrophil
157
- 251.0 plasmacytoid dendritic cell
 
1
  Neighborhoods Enriched Label
2
+ 183.0 muscle cell
3
+ 276.0 gut endothelial cell
4
+ 225.0 vascular associated smooth muscle cell
5
+ 175.0 transit amplifying cell of large intestine
6
+ 172.0 paneth cell of epithelium of large intestine
7
+ 233.0 respiratory mucous cell
8
+ 82.0 serous cell of epithelium of trachea
9
+ 184.0 epithelial cell of uterus
10
+ 259.0 adventitial cell
11
+ 282.0 type i pneumocyte
12
+ 110.0 keratinocyte
13
+ 288.0 naive regulatory t cell
14
+ 133.0 hillock-club cell of prostate epithelium
15
+ 248.0 ciliated cell
16
+ 243.0 pancreatic pp cell
17
+ 139.0 liver dendritic cell
18
+ 147.0 erythroid progenitor
19
+ 127.0 cd8-positive, alpha-beta cytotoxic t cell
20
+ 193.0 salivary gland cell
21
+ 92.0 ciliated epithelial cell
22
+ 224.0 small intestine goblet cell
23
+ 201.0 myofibroblast cell
24
+ 240.0 mature enterocyte
25
+ 281.0 pancreatic beta cell
26
+ 224.0 artery endothelial cell
27
+ 144.0 bladder urothelial cell
28
+ 147.0 transit amplifying cell of small intestine
29
+ 399.0 cell of skeletal muscle
30
+ 230.0 ciliary body
31
+ 257.0 myeloid dendritic cell
32
+ 188.0 retinal blood vessel endothelial cell
33
+ 261.0 fibroblast of cardiac tissue
34
+ 128.0 duct epithelial cell
35
+ 209.0 retinal pigment epithelial cell
36
+ 146.0 intrahepatic cholangiocyte
37
+ 119.0 t follicular helper cell
38
+ 257.0 bronchial smooth muscle cell
39
+ 156.0 microglial cell
40
+ 198.0 epithelial cell
41
+ 126.0 tracheal goblet cell
42
+ 348.0 myometrial cell
43
+ 332.0 eye photoreceptor cell
44
+ 252.0 naive thymus-derived cd4-positive, alpha-beta t cell
45
+ 137.0 kidney epithelial cell
46
+ 275.0 connective tissue cell
47
+ 136.0 cd4-positive helper t cell
48
+ 331.0 corneal keratocyte
49
+ 446.0 nk cell
50
+ 151.0 epithelial cell of lacrimal sac
51
+ 258.0 schwann cell
52
+ 260.0 intermediate monocyte
53
+ 128.0 immature enterocyte
54
+ 115.0 non-classical monocyte
55
+ 256.0 smooth muscle cell
56
+ 150.0 vein endothelial cell
57
+ 149.0 intestinal tuft cell
58
+ 361.0 lacrimal gland functional unit cell
59
+ 158.0 hepatocyte
60
+ 166.0 plasma cell
61
+ 308.0 classical monocyte
62
+ 227.0 luminal epithelial cell of mammary gland
63
+ 224.0 intestinal enteroendocrine cell
64
  113.0 endothelial cell of vascular tree
65
+ 157.0 retinal bipolar neuron
66
+ 138.0 adipocyte
67
+ 477.0 ocular surface cell
68
+ 195.0 fast muscle cell
69
+ 131.0 immature natural killer cell
70
+ 156.0 cd4-positive, alpha-beta memory t cell
71
+ 126.0 club cell of prostate epithelium
72
+ 92.0 mesothelial cell
73
+ 121.0 pancreatic acinar cell
74
+ 118.0 intestinal crypt stem cell
75
+ 159.0 basal cell
76
+ 198.0 duodenum glandular cell
77
+ 300.0 alveolar fibroblast
78
+ 143.0 corneal epithelial cell
79
+ 148.0 granulocyte
80
+ 112.0 pancreatic alpha cell
81
+ 367.0 pulmonary ionocyte
82
+ 174.0 secretory cell
83
+ 75.0 cd141-positive myeloid dendritic cell
84
+ 202.0 large intestine goblet cell
85
+ 188.0 myeloid cell
86
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87
+ 207.0 type ii pneumocyte
88
+ 110.0 ionocyte
89
+ 280.0 immune cell
90
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91
+ 493.0 capillary endothelial cell
92
+ 144.0 langerhans cell
93
+ 334.0 monocyte
94
+ 132.0 skeletal muscle satellite stem cell
95
+ 261.0 enterocyte of epithelium of large intestine
96
+ 143.0 dn1 thymic pro-t cell
97
+ 144.0 mesenchymal stem cell
98
+ 132.0 cd1c-positive myeloid dendritic cell
99
+ 219.0 serous cell of epithelium of bronchus
100
+ 244.0 muller cell
101
+ 67.0 b cell
102
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103
+ 120.0 melanocyte
104
+ 239.0 retinal ganglion cell
105
+ 150.0 basal cell of prostate epithelium
106
+ 167.0 endothelial cell
107
+ 407.0 enterocyte of epithelium of small intestine
108
+ 179.0 cd8-positive, alpha-beta cytokine secreting effector t cell
109
+ 145.0 dn4 thymocyte
110
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111
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112
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113
+ 312.0 fibroblast
114
+ 239.0 hillock cell of prostate epithelium
115
+ 518.0 retina horizontal cell
116
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117
+ 264.0 bronchial vessel endothelial cell
118
+ 182.0 medullary thymic epithelial cell
119
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120
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121
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122
+ 242.0 limbal stromal cell
123
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124
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125
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126
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127
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128
+ 215.0 intestinal crypt stem cell of small intestine
129
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130
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131
+ 203.0 paneth cell of epithelium of small intestine
132
+ 168.0 double-positive, alpha-beta thymocyte
133
+ 115.0 mature conventional dendritic cell
134
+ 97.0 pancreatic delta cell
135
+ 92.0 memory b cell
136
+ 97.0 mature nk t cell
137
  124.0 stromal cell
138
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139
+ 104.0 radial glial cell
140
+ 280.0 respiratory goblet cell
141
+ 76.0 sperm
142
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143
+ 199.0 endothelial cell of artery
144
+ 148.0 pericyte cell
145
+ 325.0 tendon cell
146
+ 201.0 limbal stem cell
147
+ 203.0 club cell
148
+ 235.0 fibroblast of breast
149
+ 244.0 macrophage
150
+ 157.0 mucus secreting cell
151
  446.0 tongue muscle cell
152
+ 303.0 acinar cell of salivary gland
153
+ 175.0 cardiac endothelial cell
154
+ 112.0 myoepithelial cell
155
+ 383.0 intestinal crypt stem cell of large intestine
156
+ 235.0 cd24 neutrophil
157
+ 330.0 plasmacytoid dendritic cell