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Levine Children's Hospital

Levine Children's Hospital

Respiratory Distress Syndrome

What Is Respiratory Distress Syndrome?

Respiratory distress syndrome (RDS) is a breathing problem that affects newborns, mostly those who are born more than 6 weeks early. The earlier or more premature a baby is born, the more likely the baby will develop RDS.

Many babies with milder symptoms get better in 3–4 days. Those who are very premature may take longer to recover.

What Are the Signs & Symptoms of Respiratory Distress Syndrome?

Within minutes or hours of being born, a baby with RDS will have breathing problems. If untreated, these problems get worse over time.

Symptoms of RDS include:

  • fast breathing
  • noisy breathing or grunting
  • a blue tint in the lips, nail beds, and skin from lack of oxygen, called

What Happens in Respiratory Distress Syndrome?



When a baby with RDS tries to breathe:

  • many of the alveoli cave in and can't open
  • oxygen can't get to the blood
  • carbon dioxide can't leave the body

If untreated, in time this can damage a baby's brain and other vital organs.

How Is Respiratory Distress Syndrome Diagnosed?

Health care providers will suspect RDS in a premature baby who has trouble breathing and needs oxygen soon after birth. A chest X-ray of the lungs can confirm the diagnosis.

How Is Respiratory Distress Syndrome Treated?

To help prevent respiratory distress syndrome, doctors can give steroid medicines to pregnant women who are likely to deliver their babies early (before 37 weeks of gestation). Steroids help the baby's lungs mature and make more surfactant before the baby is born.

Doctors will give oxygen to a baby who has signs of RDS and breathing trouble. If breathing problems continue, the baby may need continuous positive airway pressure (CPAP). With CPAP:

  • The baby wears a mask or a  that's connected to a machine.
  • The machine sends a stream of air or oxygen into the lungs through the nose.

CPAP opens the alveoli, supplies oxygen, and prevents the alveoli from collapsing. A baby who continues to have signs of respiratory distress or trouble maintaining a good oxygen level may need more support with a breathing machine or ventilator.

Babies with RDS may need treatment with surfactant. Doctors give surfactant through a breathing tube right into the lungs.

Babies with RDS get treatment in a neonatal intensive care unit (NICU). There, a team of experts cares for these newborns, including:

  • doctors who specialize in newborn care (neonatologists)
  • skilled nurses and neonatal nurse practitioners
  • respiratory therapists, who help with breathing machines

Many babies start to get better within 3 to 4 days, as their lungs start to make surfactant on their own. They'll start to breathe easier, look comfortable, need less oxygen, and can be weaned from the support of CPAP or a ventilator. Some babies — especially very premature babies — need longer treatment until they can breathe on their own.

What Else Should I Know?

Respiratory support with oxygen and a ventilator helps newborn babies with respiratory distress. But long-term use can damage a premature baby's lungs. Some babies born very early need oxygen support for a long time, leading to a condition called bronchopulmonary dysplasia (BPD).

Reviewed by: Ashish O. Gupta, MD
Date reviewed: January 2020