Mobile Site ›

Chronic Granulomatous Disease (CGD)

Clinical Features and Laboratory Testing


Receive notification when new Hot Topics are published:

Mechanisms of Innate Immunity

Slide 6

January 2010

As discussed in the previous slide, the phagocytes and complement are integral components of the innate immune response. The phagocytes can be subdivided into 2 groups - macrophages and monocytes, and neutrophils. Neutrophils typically can be considered the "first responders or EMTs" of the innate immune compartment. However, in submucosal tissue macrophages are the first to encounter pathogens and are later reinforced by neutrophils. Again as mentioned in the previous slide, both macrophages and neutrophils recognize pathogens by means of cell-surface receptors that can distinguish between surface molecules displayed by the host and the pathogen.



Jump to section: