The Body: The Complete HIV/AIDS Resource
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Lipodystrophy and WastingLipodystrophy and Wasting
Rollover images to visit our other forums!
  • Email Email
  • Glossary Glossary

What is it about protease inhibitors anyway?
Dec 7, 2003

Since it seems like protease inhibitors are one big problem in lipodystrophy, what is it that a protease inhibitor does that is good? Also this may be naive on my part but if inhibiting protease is bad, why wouldn't fostering protease be good? Does something about protease encourage or help HIV?

Response from Dr. Moyle

Inhibiting HIV protease, a key viral enzyme drammatically reduces viral load and began the revolution in HIV therapy that has saved so many lives in the developed world. Unfortunately, some members of this drug class interact with essential human enzymes/receptors so there are some side effects. Newer protease inhibitors such as atazanavir don't seem to interact so much with human proteins so may have less side effects Regards Graeme

Problems with using newfill and silkon1000?
TNF Alpha/lipoatrophy and lipodystrophy

  • Email Email
  • Glossary Glossary





Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint