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Does the frequency of virtual particles (creation/annihilation) match with nucleus random paths - known as Quantum Brownian Motion?

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As far as my knowledge goes, the creation and annihilation of virtual particles are just a bookkeeping method for physicists when they model particle interactions. That is, virtual particles aren't actually particles, and it's thus nonsensical to describe the frequency of their creation/annihilation.

This website here explains the concept of virtual particles well.

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So what is the cause of the nucleus random path? –  Hakim Jul 3 '13 at 20:41
NB: The link doesn't work. –  Hakim Jul 3 '13 at 20:41

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