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Alternative Title: dysrhythmia

Arrhythmia, variation from the normal rate or regularity of the heartbeat, usually resulting from irregularities within the conduction system of the heart. Arrhythmias occur in both normal and diseased hearts and have no medical significance in and of themselves, although they may endanger heart function when coupled with other cardiac abnormalities.

Types of arrhythmias include tachycardia, which is a regular acceleration of the heart rate; bradycardia, a regular slowing of the heart rate; and premature atrial or ventricular beats, which are extra contractions within otherwise normal heart rhythm. While occasional irregularities are normal, prolonged or chronic arrhythmias associated with some forms of heart disease may reduce cardiac output, lowering blood pressure and affecting the perfusion of vital organs with blood, and can precipitate heart failure. Severe arrhythmias can trigger atrial fibrillation or ventricular fibrillation, in which the heart beats ineffectively at many times its normal rate.

Arrhythmias reflect the failure of the sinoatrial node, the normal cardiac pacemaker, to maintain a regular heartbeat, usually because of defects in the various pathways by which electrical impulses are carried to different areas of the heart. Anatomical defects or disease can slow down or speed up the propagation of electrical impulses, causing them to arrive out of the normal rhythm, or can turn the impulses back on their path, short-circuiting the pacemaker. Many arrhythmias can be corrected through physical methods, such as artificial pacemakers, defibrillators, and radiofrequency ablation (the application of radiofrequency energy to the area of the heart that is causing the arrhythmia), or by drugs such as beta-blockers and calcium channel blockers.

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in cardiovascular disease

Rhythm disturbances in the atrium can occur as a result of increased or decreased conduction rate, both of which may potentially compromise cardiac function. The electrophysiologic mechanisms for these changes are important with respect to prognosis and treatment.
Instantaneous cardiac death is usually due to ventricular fibrillation (an uncontrolled and uncoordinated twitching of the ventricle muscle), with total mechanical inadequacy of the heart and erratic and ineffective electrical activity. Sudden death may occur without any previous manifestations of coronary heart disease. It may occur in the course of angina pectoris and causes about one-half of...
...indicative of disease. The heart rate increases in the feverish patient. A weak, rapid pulse rate may be a sign of severe blood loss or of disease within the heart itself. Irregularity of the pulse (arrhythmia) is an important indicator of heart malfunction.
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